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Elsevier

Libros en Neurociencia

  • Mental and Neurological Public Health

    A Global Perspective
    • 1 Edición
    • Vikram Patel + 4 más
    • Inglés
    Colin Mathers who leads the Global Burden of Disease group in WHO has confirmed that, in the 2004 GBD, 13.1% of global Daily Adjusted Life Years are attributable to mental or neurological disorders. While the proportions vary very widely from about 10% in low income countries to over 25% in high income countries, it is clear that there is a need for understanding how to address this issue. This volume aims to provide a comprehensive overview of the public health principles of mental and neurological disorders. This vast range of health conditions affects people across the life course, from developmental disabilities in childhood, to schizophrenia and substance abuse in adults, and dementia in old age. Despite this diversity, they all share many features: they are mostly mediated through brain dysfunction or abnormalities, are often chronic in course, typically benefit from multi-component interventions, and are amongst the most neglected conditions in global health. The volume will bring together chapters from the Psychiatry, Neurology, Substance Abuse and Child Development sections of the Encyclopedia of Public Health. The volume will be the first comprehensive text on a public health approach to this diverse group of health conditions and has no obvious competitor.

  • Practice Management in Neurology, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 28-2
    • Orly Avitzur
    • Inglés
    In the fast-paced world of health care clinical effectiveness relies not only upon medical, but also administrative competence. This issue of Neurologic Clinics features 14 articles from experts in their respective areas of office management. Articles include practice and compensation models; negotiating with payers; using benchmarks; web based neurology resources (clinical); web based neurology resources (practice management); use of electronic health records in neurology practice; hot topics in risk management; HIPPA and other regulatory issues; ethical issues; new concepts in residency and fellowship training; using evidence based medicine; P4P and PQRI; patient education; and the future of neurology.

  • The Psychology of Learning and Motivation

    • 1 Edición
    • Volumen 52
    • Inglés
    The Psychology of Learning and Motivation series publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 51 includes chapters on such varied topics as emotion and memory interference, electrophysiology, mathematical cognition, and reader participation in narrative.

  • Cognition, Brain, and Consciousness

    Introduction to Cognitive Neuroscience
    • 2 Edición
    • Bernard J. Baars + 1 más
    • Inglés
    Cognition, Brain, and Consciousness, Second Edition, provides students and readers with an overview of the study of the human brain and its cognitive development.It discusses brain molecules and their primary function, which is to help carry brain signals to and from the different parts of the human body. These molecules are also essential for understanding language, learning, perception, thinking, and other cognitive functions of our brain. The book also presents the tools that can be used to view the human brain through brain imaging or recording.New to this edition are Frontiers in Cognitive Neuroscience text boxes, each one focusing on a leading researcher and their topic of expertise. There is a new chapter on Genes and Molecules of Cognition; all other chapters have been thoroughly revised, based on the most recent discoveries.This text is designed for undergraduate and graduate students in Psychology, Neuroscience, and related disciplines in which cognitive neuroscience is taught.

  • Handbook of Basal Ganglia Structure and Function

    • 1 Edición
    • Volumen 24
    • Heinz Steiner + 1 más
    • Inglés
    The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiologic... mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction.

  • Bacterial Infections of the Central Nervous System

    • 1 Edición
    • Volumen 96
    • Karen L. Roos + 1 más
    • Inglés
    Bacterial Infections of the Central Nervous System aims to provide information useful to physicians taking care of patients with bacterial infections in the central nervous system (CNS), which can lead to morbidity and mortality. The increased number of patients suffering from this infection has led to the development of vaccines and antibiotics. Comprised of four chapters, the book explains the general approach to patients with bacterial CNS infection. It also discusses various CNS infection concepts and terms. These include the characteristic neuroimaging appearance of specific bacterial infections, the limitations of neuroimaging, the cerebrospinal fluid analysis, the pathogenesis and pathophysiology of bacterial CNS infections, the developments of specific adjunctive strategies, and the principles of antimicrobial therapy. It also includes discussions on various diseases that target the CNS, such as meningitis, focal CNS infections, neurological complications of endocarditis, suppurative venous sinus thrombosis, infections in the neurosurgical patient, and CNS diseases caused by selected infectious agents and toxins. This book will serve as a guide for clinical physicians who have patients suffering from bacterial CNS infection.

  • Neurology and Systemic Disease, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 28-1
    • Alireza Minagar
    • Inglés
    This issue of Neurologic Clinics features 17 articles that address the neurologic implications of systemic illnesses. Articles include neurologic presentations of infective endocardititis; neurologic presentations of acid-base imbalance, electrolyte abnormalities, and endocrine emergencies; neurologic presentation of renal disease; neurologic manifestations of systemic lupus erythematosus in children and adults; neurologic complications of respiratory disease; neurologic presentations of nutritional deficiencies; neurologic presentations of gastrointestinal disease; neurotoxicity of radiation therapy; neurologic presentation of lyme disease and syphilis; neurologic aspects of drug abuse; neurologic manifestations of transplant complications; neurologic presentations of sarcoidosis; neurologic presentations of fungal infections; neurologic presentations of cardiac disease; neurologic presentation of AIDS; neurologic presentation of systemic vasculitis; and neurologic presentations of hepatic disease.

  • The Brain and Host Defense

    • 1 Edición
    • Volumen 9
    • Inglés
    It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune systems.Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included with particular reference to the role of the hypothalamus, which is also the main director the hormonal regulation of immune/inflammatory. Gender-related differences in immune responsiveness, circadian modulator of immune responses, and evidence that behavioral conditioning (e.g. reward) of immune responses is possible are used as examples to reinforce the notion that the neuroendocrine system exerts a fundamental and complex regulatory influence on the immune system.

  • Nanoneuroscience and Nanoneuropharmacology

    • 1 Edición
    • Volumen 180
    • Hari S. Sharma
    • Inglés
    This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience. All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.

  • Handbook of the Behavioral Neurobiology of Serotonin

    • 1 Edición
    • Volumen 21
    • Christian P. Muller + 1 más
    • Inglés
    Serotonin (5-hydroxytryptamine... often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders.

  • Cultural Neuroscience: Cultural Influences on Brain Function

    • 1 Edición
    • Volumen 178
    • Juan Y. Chiao
    • Inglés
    This volume presents recent empirical advances using neuroscience techniques to investigate how culture influences neural processes underlying a wide range of human abilities, from perception and scene processing to memory and social cognition. It also highlights the theoretical and methodological issues with conducting cultural neuroscience research. Section I provides diverse theoretical perspectives on how culture and biology interact are represented. Sections II –VI is to demonstrate how cultural values, beliefs, practices and experience affect neural systems underlying a wide range of human behavior from perception and cognition to emotion, social cognition and decision-making. The final section presents arguments for integrating the study of culture and the human brain by providing an explicit articulation of how the study of culture can inform the study of the brain and vice versa.

  • Genetic Models of Schizophrenia

    • 1 Edición
    • Volumen 179
    • Akira Sawa
    • Inglés
    This is a well-established international series that examines major areas of basic and clinical research within neuroscience (as well as emerging and promising subfields): neuroanatomy, neurophysiology, neuroimaging, neurobiology, neuropharmacology, neuroendocrinology, neuropathology, neuropsychiatry, and neurobehavior. This volume provides a thorough treatment of gene models of schizophrenia, presenting articles from leading contributors in this important area.

  • Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders

    • 1 Edición
    • Volumen 89
    • XIAO-HONG LU
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of articles covering Novel Approaches to Studying Basal Ganglia and Related Neuropsychiatric Disorders. Topics covered include molecular profiling of direct and indirect striatal medium spiny neurons, the role of epigenetics in development and function of basal ganglia and transgenic animal models for Parkinson's disease.

  • New Concepts of Psychostimulants Induced Neurotoxicity

    • 1 Edición
    • Volumen 88
    • Hari Shanker Sharma
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. With recent advancements in new knowledge, it has become evident that psychostimulants and related drugs of abuse are influencing our central nervous system (CNS) remarkably and could alter their function for a longtime. This volume is the first to focus on substance abuse induced brain pathology in the widest sense as it covers alterations in neuronal, glial and endothelial cell functions under the influence of acute or chronic usage of substance abuse.

  • Handbook of Mammalian Vocalization

    An Integrative Neuroscience Approach
    • 1 Edición
    • Volumen 19
    • Stefan M Brudzynski
    • Inglés
    Handbook of Mammalian Vocalization is designed as a broad and comprehensive, but well-balanced book, written from the neuroscience point of view in the broad sense of this term. This well-illustrated Handbook pays particular attention to systematically organized details but also to the explanatory style of the text and internal cohesiveness of the content, so the successive chapters gradually develop a consistent story without losing the inherent complexity. Studies from many species are included, however rodents dominate, as most of the brain investigations were done on these species. The leading idea of the Handbook is that vocalizations evolved as highly adaptive specific signals, which are selectively picked up by the brain. The brain serves as a receptor and behavioural amplifier. Brain systems will be described, which allow vocal signals rapidly changing the entire state of the organism and trigger vital biological responses, usually also with accompanying emission of vocalizations. Integrative brain functions leading to vocal outcome will be described, along with the vocalization generators and motor output to larynx and other supportive motor subsystems. The last sections of the Handbook explains bioacoustic structure of vocalizations, present understanding of information coding, and origins of the complex semiotic/ semantic content of vocalizations in social mammals. The Handbook is a major source of information for professionals from many fields, with a neuroscience approach as a common denominator. The handbook provides consistent and unified understanding of all major aspects of vocalization in a monographic manner, and at the same time, gives an encyclopaedic overview of major topics associated with vocalization from molecular/ cellular level to behavior and cognitive processing. It is written in a strictly scientific way but clear enough to serve not only for specialized researchers in different fields of neuroscience but also for academic teachers of neuroscience, including behavioural neuroscience, affective neuroscience, clinical neuroscience, neuroethology, biopsychology, neurolingusitics, speech pathology, and other related fields, and also for research fellows, graduate and other advanced students, who widely need such a source publication.

  • Coma Science

    • 1 Edición
    • Volumen 177
    • Professor Laureys
    • Inglés
    This serial is firmly established as an extensive documentation of the advances in contemporary brain research. Each volume presents authoritative reviews and original articles by invited specialists.This volume concentrates on coma and consciousness science. presenting articles from leading figures in the area on the clinical and ethical implications of work in this field. The book provides a thorough review of the various aspects of coma science from a review of the concepts, questioning of recent advances, case studies, through to where research in the field is heading.

  • Essential Bioimaging Methods

    • 1 Edición
    • P. Michael Conn
    • Inglés
    Need a tested, reliable method that works? Put Essential Bioimaging Methods to work for you. Editor Michael Conn has hand-picked the most robust methods from his previously-published volumes in the Methods in Enzymology series. Many of these methods have been briefly updated by the authors that created them and use them in their research, and this book further refines and organizes existing content and focuses on methods that work, including MRI, fMRI, PET, Microscopic optical imaging and other. Part of the Reliable Lab Solution series, this volume provides clear advice and explicit protocols, providing updates to classic, tried-and-true methods and an essential addition to the bookshelf or workbench of any researcher in the field.

  • Developmental Neurobiology

    • 1 Edición
    • Greg Lemke
    • Inglés
    Developmental Neuroscience is one of the six core disciplines in Neuroscience, and yet no single volume, non-textbook reference exists on the market that provides researchers with more in-depth, high-level information on developmental neurobiology. Currently, anyone interested in the field at a higher level must sift through review articles published frequently and the more specific handbooks that focus on aspects of development rather than the field as a whole. This reference is the first of its kind to fill this need. It pulls together the relevant articles on the topic from the 10-volume Encyclopedia of Neuroscience (Academic Press, 2008) and serves as an affordable and immediate resource for scientists, postdocs, graduate students with an interest beyond the basic textbook materials on the subject.

  • Intercellular Communication in the Nervous System

    • 1 Edición
    • Robert Malenka
    • Inglés
    Intercellular communication is part of a complex system of communication that governs basic cellular activities and coordinates cell actions. The ability of cells to perceive and correctly respond to their environment is the basis of growth and development, tissue repair, and immunity as well as normal tissue homeostasis. Errors in cellular information processing are responsible for diseases such as cancer, autoimmunity, diabetes, and neurological and psychiatric disorders. There is substantial drug development concentrating on this and intercellular communication is the basis of much of neuropharmacology. By understanding cell signaling, diseases may be treated effectively and, theoretically, artificial tissues may be yielded. Neurotransmitters/re... synaptic structure and organization, gap junctions, neurotrophic factors and neuropeptides are all explored in this volume, as are the ways in which signaling controls neuroendocrinology, neuroimmunology and neuropharmacology. Intercellular Communication in the Nervous System provides a valuable desk reference for all scientists who consider signaling.

  • Mechanisms of Memory

    • 2 Edición
    • J. David Sweatt
    • J. David Sweatt
    • Inglés
    This fully revised second edition provides the only unified synthesis of available information concerning the mechanisms of higher-order memory formation. It spans the range from learning theory, to human and animal behavioral learning models, to cellular physiology and biochemistry. It is unique in its incorporation of chapters on memory disorders, tying in these clinically important syndromes with the basic science of synaptic plasticity and memory mechanisms. It also covers cutting-edge approaches such as the use of genetically engineered animals in studies of memory and memory diseases. Written in an engaging and easily readable style and extensively illustrated with many new, full-color figures to help explain key concepts, this book demystifies the complexities of memory and deepens the reader’s understanding.

  • Stress Science

    Neuroendocrinology
    • 1 Edición
    • George Fink
    • Inglés
    Stress is a universal phenomenon that impacts adversely on most people. This volume provides a readily accessible compendium that explains the phenomenon of stress, the neural, endocrine and molecular mechanisms involved, the clinical effects, and the impact on individuals and society. Clinical attention focuses on disorders of the stress control system (e.g. Cushing’s Syndrome: Addison’s Disease) and the adverse impact of stress on human physical and mental health . Detailed reviews address disorders such as PTSD, anxiety, major depression, psychoses and related disorders such as combat fatigue and burnout. The work covers interactions between stress and neurodegenerative disorders, such as Alzheimer’s disease and Parkinson’s disease, as well as stress-immune-inflam... interactions in relation to cancer and autoimmune and viral diseases. Emphasis is also placed on the role of stress in obesity, hypertension, diabetes type II and other features of the metabolic syndrome which has now reached epidemic proportions in the USA and other countries.

  • Guide to Research Techniques in Neuroscience

    • 1 Edición
    • Matt Carter + 1 más
    • Inglés
    Neuroscience is by definition a multidisciplinary field: some scientists study genes and proteins at the molecular level while others study neural circuitry. A single topic such as the auditory system can be studied using techniques from genetics, imaging, biochemistry, or electrophysiology. A young scientist must learn how to read the primary literature and then develop their own experiments. This book offers that scientist an overview of mainstream research techniques, provides guidelines on how to choose one technique over another, offers tips on analyzing data, and provides a list of references for additional detailed study. This book can also assist an experienced scientist understand published studies conducted outside their own subfield.

  • The Psychology of Learning and Motivation

    Advances in Research and Theory
    • 1 Edición
    • Volumen 51
    • Inglés
    The Psychology of Learning and Motivation series publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter thoughtfully integrates the writings of leading contributors, who present and discuss significant bodies of research relevant to their discipline. Volume 51 includes chapters on such varied topics as emotion and memory interference, electrophysiology, mathematical cognition, and reader participation in narrative.

  • Principles of Behavioral Genetics

    • 1 Edición
    • Robert R.H. Anholt + 1 más
    • Inglés
    Principles of Behavioral Genetics provides an introduction to the fascinating science that aims to understand how our genes determine what makes us tick. It presents a comprehensive overview of the relationship between genes, brain, and behavior. Introductory chapters give clear explanations of basic processes of the nervous system and fundamental principles of genetics of complex traits without excessive statistical jargon. Individual chapters describe the genetics of social interactions, olfaction and taste, memory and learning, circadian behavior, locomotion, sleep, and addiction, as well as the evolution of behavior. Whereas the focus is on genetics, neurobiological and ecological aspects are also included to provide intellectual breadth. The book uses examples that span the gamut from classical model organisms to non-model systems and human biology, and include both laboratory and field studies. Samples of historical information accentuate the text to provide the reader with an appreciation of the history of the field. This book will be a valuable resource for future generations of scientists who focus on the field of behavioral genetics.

  • The Neuroscience of Sleep

    • 1 Edición
    • Robert Stickgold + 1 más
    • Inglés
    Sleep is the natural state of bodily rest, common to all mammals and birds and also seen in many reptiles, amphibians and fish. For most species, regular sleep is essential for survival, yet the specific purposes of sleep are still only partly clear and are the subject of intense research. This volume is comprised of the editors’ selection of the most relevant articles on sleep from the Encyclopedia of Neuroscience, resulting in the first comprehensive collection of introductory articles on the neuroscience of sleep. Articles explore sleep’s impact on neural functioning, sleep disorders, the relation between sleep and other clinical disorders, a look at sleep from a developmental perspective, and more.

  • Attention

    • 1 Edición
    • Volumen 176
    • Narayanan Srinivasan
    • Inglés
    This well-established international series examines major areas of basic and clinical research within neuroscience, as well as emerging and promising subfields. This volume explores interdisciplinary research on Attention and interaction of Attention with other cognitive processes including perception, learning, and memory. The papers cover major research on attention in Cognitive Neuroscience and Cognitive Psychology. The volume presents recent advances on attention including binding, dynamics of attention, attention and perceptual organization, attention and consciousness, emotion and attention, development of attention, crossmodal attention, computational modeling of attention, control of actions, attention and memory, and meditation.

  • Neurotherapy

    Progress in Restorative Neuroscience and Neurology
    • 1 Edición
    • Volumen 175
    • Joost Verhaagen + 6 más
    • Inglés
    This book focuses on the exciting recent progress in restorative neurology and neuroscience. The book includes chapters on major neurodegenerative disorders of the brain and the visual system, including Parkinson's disease, Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, macular degeneration, retinitis pigmentosa, glaucoma, spinal cord trauma, and multiple sclerosis. The primary goal of the book is to give an overview of new developments in translational research and in potential therapeutic strategies, including stem cell therapy, immunotherapy, gene therapy, pharmacotherapy, neuroprostheses and deep brain stimulation.

  • Physiology and Pathology of Chloride Transporters and Channels in the Nervous System

    From Molecules to Diseases
    • 1 Edición
    • F. Javier Alvarez-Leefmans + 1 más
    • Inglés
    The importance of chloride ions in cell physiology has not been fully recognized until recently, in spite of the fact that chloride (Cl-), together with bicarbonate, is the most abundant free anion in animal cells, and performs or determines fundamental biological functions in all tissues. For many years it was thought that Cl- was distributed in thermodynamic equilibrium across the plasma membrane of most cells. Research carried out during the last couple of decades has led to a dramatic change in this simplistic view. We now know that most animal cells, neurons included, exhibit a non-equilibrium distribution of Cl- across their plasma membranes. Over the last 10 to 15 years, with the growth of molecular biology and the advent of new optical methods, an enormous amount of exciting new information has become available on the molecular structure and function of Cl- channels and carriers. In nerve cells, Cl- channels and carriers play key functional roles in GABA- and glycine-mediated synaptic inhibition, neuronal growth and development, extracellular potassium scavenging, sensory-transduction... neurotransmitter uptake and cell volume control. Disruption of Cl- homeostasis in neurons underlies pathological conditions such as epilepsy, deafness, imbalance, brain edema and ischemia, pain and neurogenic inflammation. This book is about how chloride ions are regulated and how they cross the plasma membrane of neurons. It spans from molecular structure and function of carriers and channels involved in Cl- transport to their role in various diseases.

  • Essays on Peripheral Nerve Repair and Regeneration

    • 1 Edición
    • Volumen 87
    • Stefano Geuna + 2 más
    • Inglés
    Interest in the study of peripheral nerve repair and regeneration has increased significantly over the last twenty years and today the number of nerve reconstructions performed is progressively increasing due to the continuous improvement in surgical technology and to the spread of microsurgical skills among surgeons worldwide. This volume of International Review of Neurobiology providdes an overview of the state of the art knowledge in peripheral nerve repair and regeneration by bringing together a number of reviews that critically address some the most important issues in this biomedical field.

  • Advances in Neuropharmacology

    • 1 Edición
    • Volumen 85
    • Giacinto Bagetta + 3 más
    • Inglés
    This volume provides a broad overview of important new advances in the field of Neuropharmacology. In 20 chapters, a selection of international contributors discuss topics including endocannabinoid function, pain, stress, astrocytes etc, and new possibilities for treatments of neurological diseases with neuropharmacological approaches.

  • Human Motor Control

    • 2 Edición
    • David A. Rosenbaum
    • Inglés
    Motor Control is a complex process that involves the brain, muscles, limbs, and often external objects. It underlies motion, balance, stability, coordination, and our interaction with others and technology. This book is a comprehensive introduction to motor control, covering a complex topic in an approachable way encompassing the psychological, physiological, and computational approaches to motor control. Human Motor Control, 2e cuts across all movement related disciplines: physical education, dance, physical therapy, robotics, etc. This second edition incorporates advances to the field, and integrates throughout the book how research harkens back to four critical questions: how do we select our actions of the many actions possible? How are these behaviors sequenced for appropriate order and timing between them? How does perception integrate with motor control? And how are perceptual–motor skills acquired? As before, the book retains its signature organization around activity systems. These activity systems include walking, looking, reaching, drawing and writing, keyboarding, speaking and singing, and smiling. Chapters here exemplify rather than encompass all the behaviors related to them. Hence smiling discusses physical and neural control of the face used in other expressions besides smiling, as well as the origins of emotional expression, and the importance of emotion expression in social interaction. These chapters on activity systems are preceded by chapters on basics, with an introduction and information on the physiological and psychological foundations of movement. The last section discusses integration of movements, individual differences, theories of motor control, and the contributions of both genetics and technology to motor control. Special features of the second edition:Organization by major activity systems New: brain imaging, social action, embodied cognition, advances in genetics and technology Detailed treatment of motor neuroscience Further Readings section added to each chapter

  • Evolutionary Neuroscience

    • 1 Edición
    • Jon H. Kaas
    • Inglés
    Evolutionary Neuroscience is a collection of articles in brain evolution selected from the recent comprehensive reference, Evolution of Nervous Systems (Elsevier, Academic Press, 2007). The selected chapters cover a broad range of topics from historical theory to the most recent deductions from comparative studies of brains. The articles are organized in sections focused on theories and brain scaling, the evolution of brains from early vertebrates to present-day fishes, amphibians, reptiles and birds, the evolution of mammalian brains, and the evolution of primate brains, including human brains. Each chapter is written by a leader or leaders in the field, and has been reviewed by other experts. Specific topics include brain character reconstruction, principles of brain scaling, basic features of vertebrate brains, the evolution of the major sensory systems, and other parts of brains, what we can learn from fossils, the origin of neocortex, and the evolution of specializations of human brains. The collection of articles will be interesting to anyone who is curious about how brains evolved from the simpler nervous systems of the first vertebrates into the many different complex forms now found in present-day vertebrates. This book would be of use to students at the graduate or undergraduate levels, as well as professional neuroscientists, cognitive scientists, and psychologists. Together, the chapters provide a comprehensive list of further reading and references for those who want to inquire further.

  • Advances in the Study of Behavior

    • 1 Edición
    • Volumen 39
    • H. Jane Brockmann + 4 más
    • Inglés
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect full-text online from volume 30 onward.

  • Molecular Mechanisms of Hormone Actions on Behavior

    • 1 Edición
    • Anne M. Etgen + 1 más
    • Inglés
    A single volume of 31 articles, Mechanisms of Hormone Actions on Behavior is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinologica... information assembled to date (AP June 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinologica... topics, approaching the subject from the perspective of the mechanisms which control hormone actions on behavior. Female, male and stress hormones are discussed at the cellular, behavioral and developmental level, and sexual differentiation of the development of hormone-dependent neuronal systems, neuropeptides/neurom... and steroid-inducedneuro... are addressed. There is simply no other current single-volume reference with such comprehensive coverage and depth.Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 175 figures (over 50 in color). A collection of articles reviewing our fundamental knowledge of the mechanisms of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.

  • Hormone/Behavior Relations of Clinical Importance

    Endocrine Systems Interacting with Brain and Behavior
    • 1 Edición
    • Robert H. Rubin + 1 más
    • Inglés
    A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinologica... information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinologica... topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies... Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth.Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.

  • Language, Memory, and Cognition in Infancy and Early Childhood

    • 1 Edición
    • Janette B. Benson + 1 más
    • Inglés
    Language, cognition, and memory are traditionally studied together prior to a researcher specializing in any one area. They are studied together initially because much of the development of one can affect the development of the others. Most books available now either tend to be extremely broad in the areas of all infant development including physical and social development, or specialize in cognitive development, language acquisition, or memory. Rarely do you find all three together, despite the fact that they all relate to each other. This volume consists of focused articles from the authoritative Encyclopedia of Infant and Early Childood Development, and specifically targets the ages 0-3. Providing summary overviews of basic and cutting edge research, coverage includes attention, assessment, bilingualism, categorization skills, critical periods, learning disabilities, reasoning, speech development, etc. This collection of articles provides an essential, affordable reference for researchers, graduate students, and clinicians interested in cognitive development, language development, and memory, as well as those developmental psychologists interested in all aspects of development.

  • Diseases and Disorders in Infancy and Early Childhood

    • 1 Edición
    • Janette B. Benson + 1 más
    • Inglés
    Currently, there are two types of pediatric disorder books available: high level technical books geared toward pediatric specialists, and self-help books for parents. The technical books cover diagnosis and treatment, while the self-help books cover general problems, are single authored, and speak little to the research of any given disorder. This volume consists of focused articles from the authoritative Encyclopedia of Infant and Early Childhood Development that cover the research information on common disorders in age 0-3. Topics include those most typically occurring, making them of great interest to both specialists and nonspecialists. Disorders and dysfunction of a variety of types are discussed, whether cognitive, social, emotional, or physiological. Coverage includes asthma, allergies, colic, bedwetting, diarrhea, genetic disorders, SIDS and learning disabilities, and provides an essential, affordable reference for researchers in developmental psychology, as well as allied health fields.

  • Genetic Dissection of Neural Circuits and Behavior

    • 1 Edición
    • Volumen 65
    • Inglés
    Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

  • Handbook of the Neuroscience of Aging

    • 1 Edición
    • Patrick R. Hof + 1 más
    • Inglés
    A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008). The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers. This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology.

  • Pharmacology

    Principles and Practice
    • 1 Edición
    • Miles Hacker + 2 más
    • Inglés
    Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research.

  • Encyclopedia of Neuroscience, Volume 1

    • 1 Edición
    • Floyd E. Bloom + 4 más
    • Inglés
    The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

  • Hormones, Brain and Behavior Online

    • 2 Edición
    • Donald W. Pfaff
    • Inglés
    Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available.

  • Neurobiology of Dementia

    • 1 Edición
    • Volumen 84
    • Alireza Minagar
    • Inglés
    With recent advances of modern medicine, more people reach the “elderly age” around the globe, and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians’ and neuroscientists’ interest to carry out more research projects into the pathogenesis of this devastating group of diseases.

  • Handbook of Reward and Decision Making

    • 1 Edición
    • Jean-Claude Dreher + 1 más
    • Inglés
    This book addresses a fundamental question about the nature of behavior: how does the brain process reward and makes decisions when facing multiple options? The book presents the most recent and compelling lesion, neuroimaging, electrophysiological and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of neural mechanisms behind reward and decision making. The neural bases of reward and decision making processes are of great interest to scientists because of the fundamental role of reward in a number of behavioral processes (such as motivation, learning and cognition) and because of their theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders (schizophrenia, Parkinson's disease, drug addiction, pathological gambling, ...)

  • Encyclopedia of Basic Epilepsy Research

    • 1 Edición
    • Philip A. Schwartzkroin
    • Inglés
    As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy.

  • Mind and Motion: The Bidirectional Link between Thought and Action

    Progress in Brain Research
    • 1 Edición
    • Volumen 174
    • Markus Raab + 2 más
    • Inglés
    This volume investigates the implications of how our brain directs our movements on decision making. An extensive body of knowledge in chapters from international experts is presented as well as integrative group reports discussing new directions for future research.The understanding of how people make decisions is of central interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. For the first time the current volume provides a multidisciplinary overview of how action and cognition are integrated in the planning of and decisions about action.

  • Neuromodulation

    • 1 Edición
    • Elliot S. Krames + 2 más
    • Inglés
    Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs.The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices.All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come.

  • Diffusion MRI

    From quantitative measurement to in-vivo neuroanatomy
    • 1 Edición
    • Heidi Johansen-Berg + 1 más
    • Inglés
    Diffusion MRI is a magnetic resonance imaging (MRI) method that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion, providing an effective means of visualizing functional connectivities in the nervous system. This book is the first comprehensive reference promoting the understanding of this rapidly evolving and powerful technology and providing the essential handbook for designing, analyzing or interpreting diffusion MR experiments.The book presents diffusion imaging in the context of well-established, classical experimental techniques, so that readers will be able to assess the scope and limitations of the new imaging technology with respect to techniques available previously. All chapters are written by leading international experts and cover methodology, validation of the imaging technology, application of diffusion imaging to the study of variation and development of normal brain anatomy, and disruption to the white matter in neurological disease or psychiatric disorder.

  • From Molecules to Networks

    An Introduction to Cellular and Molecular Neuroscience
    • 2 Edición
    • Ruth Heidelberger + 3 más
    • Inglés
    An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease.

  • Psychology of Learning and Motivation

    Moral Judgment and Decision Making
    • 1 Edición
    • Volumen 50
    • Inglés
    This volume presents a variety of perspectives from within and outside moral psychology. Recently there has been an explosion of research in moral psychology, but it is one of the subfields most in need of bridge-building, both within and across areas. Interests in moral phenomena have spawned several separate lines of research that appear to address similar concerns from a variety of perspectives. The contributions to this volume examine key theoretical and empirical issues these perspectives share that connect these issues with the broader base of theory and research in social and cognitive psychology. The first two chapters discuss the role of mental representation in moral judgment and reasoning. Sloman, Fernbach, and Ewing argue that causal models are the canonical representational medium underlying moral reasoning, and Mikhail offers an account that makes use of linguistic structures and implicates legal concepts. Bilz and Nadler follow with a discussion of the ways in which laws, which are typically construed in terms of affecting behavior, exert an influence on moral attitudes, cognition, and emotions. Baron and Ritov follow with a discussion of how people's moral cognition is often driven by law-like rules that forbid actions and suggest that value-driven judgment is relatively less concerned by the consequences of those actions than some normative standards would prescribe. Iliev et al. argue that moral cognition makes use of both rules and consequences, and review a number of laboratory studies that suggest that values influence what captures our attention, and that attention is a powerful determinant of judgment and preference. Ginges follows with a discussion of how these value-related processes influence cognition and behavior outside the laboratory, in high-stakes, real-world conflicts. Two subsequent chapters discuss further building blocks of moral cognition. Lapsley and Narvaez discuss the development of moral characters in children, and Reyna and Casillas offer a memory-based account of moral reasoning, backed up by developmental evidence. Their theoretical framework is also very relevant to the phenomena discussed in the Sloman et al., Baron and Ritov, and Iliev et al. chapters. The final three chapters are centrally focused on the interplay of hot and cold cognition. They examine the relationship between recent empirical findings in moral psychology and accounts that rely on concepts and distinctions borrowed from normative ethics and decision theory. Connolly and Hardman focus on bridge-building between contemporary discussions in the judgment and decision making and moral judgment literatures, offering several useful methodological and theoretical critiques. Ditto, Pizarro, and Tannenbaum argue that some forms of moral judgment that appear objective and absolute on the surface are, at bottom, more about motivated reasoning in service of some desired conclusion. Finally, Bauman and Skitka argue that moral relevance is in the eye of the perceiver and emphasize an empirical approach to identifying whether people perceive a given judgment as moral or non-moral. They describe a number of behavioral implications of people's reported perception that a judgment or choice is a moral one, and in doing so, they suggest that the way in which researchers carve out the moral domain a priori might be dubious.

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