Saltar al contenido principal
Elsevier

Libros en Neurociencia

  • Evolutionary Neuroscience

    • 1 Edición
    • Jon H. Kaas
    • Inglés
    Evolutionary Neuroscience is a collection of articles in brain evolution selected from the recent comprehensive reference, Evolution of Nervous Systems (Elsevier, Academic Press, 2007). The selected chapters cover a broad range of topics from historical theory to the most recent deductions from comparative studies of brains. The articles are organized in sections focused on theories and brain scaling, the evolution of brains from early vertebrates to present-day fishes, amphibians, reptiles and birds, the evolution of mammalian brains, and the evolution of primate brains, including human brains. Each chapter is written by a leader or leaders in the field, and has been reviewed by other experts. Specific topics include brain character reconstruction, principles of brain scaling, basic features of vertebrate brains, the evolution of the major sensory systems, and other parts of brains, what we can learn from fossils, the origin of neocortex, and the evolution of specializations of human brains. The collection of articles will be interesting to anyone who is curious about how brains evolved from the simpler nervous systems of the first vertebrates into the many different complex forms now found in present-day vertebrates. This book would be of use to students at the graduate or undergraduate levels, as well as professional neuroscientists, cognitive scientists, and psychologists. Together, the chapters provide a comprehensive list of further reading and references for those who want to inquire further.

  • Advances in the Study of Behavior

    • 1 Edición
    • Volumen 39
    • H. Jane Brockmann + 4 más
    • Inglés
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect full-text online from volume 30 onward.

  • Molecular Mechanisms of Hormone Actions on Behavior

    • 1 Edición
    • Anne M. Etgen + 1 más
    • Inglés
    A single volume of 31 articles, Mechanisms of Hormone Actions on Behavior is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinologica... information assembled to date (AP June 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinologica... topics, approaching the subject from the perspective of the mechanisms which control hormone actions on behavior. Female, male and stress hormones are discussed at the cellular, behavioral and developmental level, and sexual differentiation of the development of hormone-dependent neuronal systems, neuropeptides/neurom... and steroid-inducedneuro... are addressed. There is simply no other current single-volume reference with such comprehensive coverage and depth.Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 175 figures (over 50 in color). A collection of articles reviewing our fundamental knowledge of the mechanisms of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.

  • Hormone/Behavior Relations of Clinical Importance

    Endocrine Systems Interacting with Brain and Behavior
    • 1 Edición
    • Robert H. Rubin + 1 más
    • Inglés
    A single volume of 41 articles, Hormone/Behavior Relations of Clinical Importance is an authoritative selection of relevant chapters from the Hormones Brain and Behavior 2e MRW, the most comprehensive source of neuroendocrinologica... information assembled to date (AP July 2009). The study of hormones as they impact the brain and, subsequently, behavior is a central topic in neuroscience, endocrinology and psychiatry. This volume offers an overview of neuroendocrinologica... topics, approaching the subject from the perspective of hormone-brain function, hormone-behavior relations, sex differences, and the impact on various diseases/pathologies... Many basic human behavioral functions are subject to the influence of hormones - sexual orientation, the experience of pain, fertility, immunity - as are clinical conditions such as diabetes, substance abuse disorder, eating disorders, PTSD, TBI, pain, Alzheimer's, stress/anxiety, affective disorders, and more. There is considerable commercial clinical potential in the study of hormones - drug companies are currently developing a Cholecystokinin (hormonal peptide) booster to reduce appetite in those who suffer from sever obesity, and catamenial epilepsy (features seizure exacerbation in relation to the menstrual cycle) is resistant to treatment by standard antiepileptic medications, but may be hormonally controlled. These issues and more are covered, and there is simply no other current single-volume reference with such comprehensive coverage and depth.Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 150 figures (50 in color). A collection of articles reviewing our fundamental knowledge of neuroendocrinology, the book provides an essential, affordable reference for researchers, clinicians and graduate students in the area.

  • Language, Memory, and Cognition in Infancy and Early Childhood

    • 1 Edición
    • Janette B. Benson + 1 más
    • Inglés
    Language, cognition, and memory are traditionally studied together prior to a researcher specializing in any one area. They are studied together initially because much of the development of one can affect the development of the others. Most books available now either tend to be extremely broad in the areas of all infant development including physical and social development, or specialize in cognitive development, language acquisition, or memory. Rarely do you find all three together, despite the fact that they all relate to each other. This volume consists of focused articles from the authoritative Encyclopedia of Infant and Early Childood Development, and specifically targets the ages 0-3. Providing summary overviews of basic and cutting edge research, coverage includes attention, assessment, bilingualism, categorization skills, critical periods, learning disabilities, reasoning, speech development, etc. This collection of articles provides an essential, affordable reference for researchers, graduate students, and clinicians interested in cognitive development, language development, and memory, as well as those developmental psychologists interested in all aspects of development.

  • Diseases and Disorders in Infancy and Early Childhood

    • 1 Edición
    • Janette B. Benson + 1 más
    • Inglés
    Currently, there are two types of pediatric disorder books available: high level technical books geared toward pediatric specialists, and self-help books for parents. The technical books cover diagnosis and treatment, while the self-help books cover general problems, are single authored, and speak little to the research of any given disorder. This volume consists of focused articles from the authoritative Encyclopedia of Infant and Early Childhood Development that cover the research information on common disorders in age 0-3. Topics include those most typically occurring, making them of great interest to both specialists and nonspecialists. Disorders and dysfunction of a variety of types are discussed, whether cognitive, social, emotional, or physiological. Coverage includes asthma, allergies, colic, bedwetting, diarrhea, genetic disorders, SIDS and learning disabilities, and provides an essential, affordable reference for researchers in developmental psychology, as well as allied health fields.

  • Genetic Dissection of Neural Circuits and Behavior

    • 1 Edición
    • Volumen 65
    • Inglés
    Genes interact with the environment, experience, and biology of the brain to shape an animal’s behavior. This latest volume in Advances in Genetics, organized according to the most widely used model organisms, describes the latest genetic discoveries in relation to neural circuit development and activity.

  • Handbook of the Neuroscience of Aging

    • 1 Edición
    • Patrick R. Hof + 1 más
    • Inglés
    A single volume of 85 articles, the Handbook of the Neurobiology of Aging is an authoritative selection of relevant chapters from the Encyclopedia of Neuroscience, the most comprehensive source of neuroscience information assembled to date (AP Oct 2008). The study of neural aging is a central topic in neuroscience, neuropsychology and gerontology. Some well-known age-related neurological diseases include Parkinson's and Alzheimer's, but even more common are problems of aging which are not due to disease but to more subtle impairments in neurobiological systems, including impairments in vision, memory loss, muscle weakening, and loss of reproductive functions, changes in body weight, and sleeplessness. As the average age of our society increases, diseases of aging become more common and conditions associated with aging need more attention by doctors and researchers. This book offers an overview of topics related to neurobiological impairments which are related to the aging brain and nervous system. Coverage ranges from animal models to human imaging, fundamentals of age-related neural changes and pathological neurodegeneration, and offers an overview of structural and functional changes at the molecular, systems, and cognitive levels. Key pathologies such as memory disorders, Alzheimer's, dementia, Down syndrome, Parkinson's, and stroke are discussed, as are cutting edge interventions such as cell replacement therapy and deep brain stimulation. There is no other current single-volume reference with such a comprehensive coverage and depth. Authors selected are the internationally renowned experts for the particular topics on which they write, and the volume is richly illustrated with over 100 color figures. A collection of articles reviewing our fundamental knowledge of neural aging, the book provides an essential, affordable reference for scientists in all areas of Neuroscience, Neuropsychology and Gerontology.

  • Pharmacology

    Principles and Practice
    • 1 Edición
    • Miles Hacker + 2 más
    • Inglés
    Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research.

  • Encyclopedia of Neuroscience, Volume 1

    • 1 Edición
    • Floyd E. Bloom + 4 más
    • Inglés
    The Encyclopedia of the Neuroscience explores all areas of the discipline in its focused entries on a wide variety of topics in neurology, neurosurgery, psychiatry and other related areas of neuroscience. Each article is written by an expert in that specific domain and peer reviewed by the advisory board before acceptance into the encyclopedia. Each article contains a glossary, introduction, a reference section, and cross-references to other related encyclopedia articles. Written at a level suitable for university undergraduates, the breadth and depth of coverage will appeal beyond undergraduates to professionals and academics in related fields.

  • Hormones, Brain and Behavior Online

    • 2 Edición
    • Donald W. Pfaff
    • Inglés
    Hormones, Brain, and Behavior, Second Edition is a comprehensive work discussing the effect of hormones on the brain and, subsequently, behavior. This major reference work has 109 chapters covering a broad range of topics with an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. To truly understand all aspects of our behavior, we must take every influence (including the hormonal influences) into consideration. Donald Pfaff and a number of well-qualified editors examine and discuss how we are influenced by hormonal factors, offering insight, and information on the lives of a variety of species. Hormones, Brain, and Behavior offers the reader comprehensive coverage of growing field of research, with a state-of-the-art overview of hormonally-mediated behaviors. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Available online exclusively via ScienceDirect. A limited edition print version is also available.

  • Handbook of Reward and Decision Making

    • 1 Edición
    • Jean-Claude Dreher + 1 más
    • Inglés
    This book addresses a fundamental question about the nature of behavior: how does the brain process reward and makes decisions when facing multiple options? The book presents the most recent and compelling lesion, neuroimaging, electrophysiological and computational studies, in combination with hormonal and genetic studies, which have led to a clearer understanding of neural mechanisms behind reward and decision making. The neural bases of reward and decision making processes are of great interest to scientists because of the fundamental role of reward in a number of behavioral processes (such as motivation, learning and cognition) and because of their theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders (schizophrenia, Parkinson's disease, drug addiction, pathological gambling, ...)

  • Neurobiology of Dementia

    • 1 Edición
    • Volumen 84
    • Alireza Minagar
    • Inglés
    With recent advances of modern medicine, more people reach the “elderly age” around the globe, and the number of dementia cases are ever increasing. This book is about various aspects of dementia and provides its readers with a wide range of thought-provoking sub-topics in the field of dementia. The ultimate goal of this monograph is to stimulate other physicians’ and neuroscientists’ interest to carry out more research projects into the pathogenesis of this devastating group of diseases.

  • Encyclopedia of Basic Epilepsy Research

    • 1 Edición
    • Philip A. Schwartzkroin
    • Inglés
    As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy.

  • Mind and Motion: The Bidirectional Link between Thought and Action

    Progress in Brain Research
    • 1 Edición
    • Volumen 174
    • Markus Raab + 2 más
    • Inglés
    This volume investigates the implications of how our brain directs our movements on decision making. An extensive body of knowledge in chapters from international experts is presented as well as integrative group reports discussing new directions for future research.The understanding of how people make decisions is of central interest to experts working in fields such as psychology, economics, movement science, cognitive neuroscience, neuroinformatics, robotics, and sport science. For the first time the current volume provides a multidisciplinary overview of how action and cognition are integrated in the planning of and decisions about action.

  • Neuromodulation

    • 1 Edición
    • Elliot S. Krames + 2 más
    • Inglés
    Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs.The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices.All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come.

  • Diffusion MRI

    From quantitative measurement to in-vivo neuroanatomy
    • 1 Edición
    • Heidi Johansen-Berg + 1 más
    • Inglés
    Diffusion MRI is a magnetic resonance imaging (MRI) method that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion, providing an effective means of visualizing functional connectivities in the nervous system. This book is the first comprehensive reference promoting the understanding of this rapidly evolving and powerful technology and providing the essential handbook for designing, analyzing or interpreting diffusion MR experiments.The book presents diffusion imaging in the context of well-established, classical experimental techniques, so that readers will be able to assess the scope and limitations of the new imaging technology with respect to techniques available previously. All chapters are written by leading international experts and cover methodology, validation of the imaging technology, application of diffusion imaging to the study of variation and development of normal brain anatomy, and disruption to the white matter in neurological disease or psychiatric disorder.

  • From Molecules to Networks

    An Introduction to Cellular and Molecular Neuroscience
    • 2 Edición
    • Ruth Heidelberger + 3 más
    • Inglés
    An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. From Molecules to Networks provides the solid foundation of the morphologic, biochemical, and biophysical properties of nerve cells. All chapters have been thoroughly revised for this second edition to reflect the significant advances of the past 5 years. The new edition expands on the network aspects of cellular neurobiology by adding a new chapter, Information Processing in Neural Networks, and on the relation of cell biological processes to various neurological diseases. The new concluding chapter illustrates how the great strides in understanding the biochemical and biophysical properties of nerve cells have led to fundamental insights into important aspects of neurodegenerative disease.

  • Psychology of Learning and Motivation

    Moral Judgment and Decision Making
    • 1 Edición
    • Volumen 50
    • Inglés
    This volume presents a variety of perspectives from within and outside moral psychology. Recently there has been an explosion of research in moral psychology, but it is one of the subfields most in need of bridge-building, both within and across areas. Interests in moral phenomena have spawned several separate lines of research that appear to address similar concerns from a variety of perspectives. The contributions to this volume examine key theoretical and empirical issues these perspectives share that connect these issues with the broader base of theory and research in social and cognitive psychology. The first two chapters discuss the role of mental representation in moral judgment and reasoning. Sloman, Fernbach, and Ewing argue that causal models are the canonical representational medium underlying moral reasoning, and Mikhail offers an account that makes use of linguistic structures and implicates legal concepts. Bilz and Nadler follow with a discussion of the ways in which laws, which are typically construed in terms of affecting behavior, exert an influence on moral attitudes, cognition, and emotions. Baron and Ritov follow with a discussion of how people's moral cognition is often driven by law-like rules that forbid actions and suggest that value-driven judgment is relatively less concerned by the consequences of those actions than some normative standards would prescribe. Iliev et al. argue that moral cognition makes use of both rules and consequences, and review a number of laboratory studies that suggest that values influence what captures our attention, and that attention is a powerful determinant of judgment and preference. Ginges follows with a discussion of how these value-related processes influence cognition and behavior outside the laboratory, in high-stakes, real-world conflicts. Two subsequent chapters discuss further building blocks of moral cognition. Lapsley and Narvaez discuss the development of moral characters in children, and Reyna and Casillas offer a memory-based account of moral reasoning, backed up by developmental evidence. Their theoretical framework is also very relevant to the phenomena discussed in the Sloman et al., Baron and Ritov, and Iliev et al. chapters. The final three chapters are centrally focused on the interplay of hot and cold cognition. They examine the relationship between recent empirical findings in moral psychology and accounts that rely on concepts and distinctions borrowed from normative ethics and decision theory. Connolly and Hardman focus on bridge-building between contemporary discussions in the judgment and decision making and moral judgment literatures, offering several useful methodological and theoretical critiques. Ditto, Pizarro, and Tannenbaum argue that some forms of moral judgment that appear objective and absolute on the surface are, at bottom, more about motivated reasoning in service of some desired conclusion. Finally, Bauman and Skitka argue that moral relevance is in the eye of the perceiver and emphasize an empirical approach to identifying whether people perceive a given judgment as moral or non-moral. They describe a number of behavioral implications of people's reported perception that a judgment or choice is a moral one, and in doing so, they suggest that the way in which researchers carve out the moral domain a priori might be dubious.

  • Introduction to Quantitative EEG and Neurofeedback

    Advanced Theory and Applications
    • 2 Edición
    • Thomas H. Budzynski + 3 más
    • Inglés
    The study of Quantitative EEGs and Neurofeedback offer a window into brain physiology and function via computer and statistical analyses, suggesting innovative approaches to the improvement of attention, anxiety, mood and behavior. Resources for understanding what QEEG and Neurofeedback is, how they are used, and to what disorders and patients they can be applied are scarce, and this volume serves as an ideal tool for clinical researchers and practicing clinicians, providing a broad overview of the most interesting topics relating to the techniques. The revised coverage of advancements, new applications (e.g. Aspberger's, music therapy, LORETA, etc.), and combinations of prior approaches make the second edition a necessary companion to the first. The top scholars in the field have been enlisted and contributions will offer both the breadth needed for an introductory scholar and the depth desired by a clinical professional.

  • Stroke Part I: Basic and Epidemiological Aspects

    • 1 Edición
    • Volumen 92
    • Marc Fisher
    • Inglés
    This volume provides a vital and comprehensive resource on stroke, including research, diagnosis, prevention, and treatment modalities. Practitioners in these fields will find invaluable information in this handbook, from basic mechanisms of the disease, to enhanced diagnostic and therapeutic capabilities for patient care. With the field of cerebrovascular disorders, including stroke, making rapid advancements, clinicians will find illuminating and insightful chapters on the pathophysiological basis of this disorder. Advances in our understanding of the biochemical background of strokes, coupled with an examination of breakthroughs in epidemiology, genetics, neuroimaging, interventional radiology, surgery, and even clinical psychology are also explored, giving researchers and clinicians a profoundly altered way to approach stroke research, diagnosis, and patient treatment and care.

  • Stroke, Part III: Investigation and Management

    • 1 Edición
    • Volumen 94
    • Marc Fisher
    • Inglés
    This volume provides a comprehensive exploration of stroke, from basic mechanisms of disease to enhanced diagnostic and therapeutic capabilities. The ongoing efforts within the neurological community are also highlighted, bringing a better understanding of the pathophysiological basis of this disorder. Clinicians will find invaluable information that can be used to enhance the lives of an aging global population. Covered topics include the functional anatomy of the brain itself, as well as advancements in the understanding of the biochemical background of strokes. Related fields and their dramatic impact on stroke research are also included, with findings in the fields of epidemiology, genetics, neuroimaging, and interventional radiology thoroughly explored. In addition, great attention is paid to therapeutic avenues, including investigation, prevention, and patient management.

  • Stroke, Part II: Clinical Manifestations and Pathogenesis

    • 1 Edición
    • Volumen 93
    • Marc Fisher
    • Inglés
    This volume provides a comprehensive guide to the manifestations and pathogenesis involved with stroke, including advancements in research and a newfound understanding of the biochemical background of this cerebrovascular disorder. This intensive handbook is meant to give clinicians a source reference that will enable them to gain a thorough knowledge and understanding of the clinical features and management of the many neurological manifestations of stroke disorder. In addition, practitioners, clinicians, and researchers will gain a better understanding of highly studied topics, including amongst others, the medical complications associated with stroke, chapters on anterior circulation and hemorrhagic stroke syndromes, stroke related psychiatric disorders, and other rare causes of stroke disorder.

  • The Spinal Cord

    A Christopher and Dana Reeve Foundation Text and Atlas
    • 1 Edición
    • Charles Watson + 2 más
    • Inglés
    Many hundreds of thousands suffer spinal cord injuries leading to loss of sensation and motor function in the body below the point of injury. Spinal cord research has made some significant strides towards new treatment methods, and is a focus of many laboratories worldwide. In addition, research on the involvement of the spinal cord in pain and the abilities of nervous tissue in the spine to regenerate has increasingly been on the forefront of biomedical research in the past years. The Spinal Cord, a collaboration with the Christopher and Dana Reeve Foundation, is the first comprehensive book on the anatomy of the mammalian spinal cord. Tens of thousands of articles and dozens of books are published on this subject each year, and a great deal of experimental work has been carried out on the rat spinal cord. Despite this, there is no comprehensive and authoritative atlas of the mammalian spinal cord. Almost all of the fine details of spinal cord anatomy must be searched for in journal articles on particular subjects. This book addresses this need by providing both a comprehensive reference on the mammalian spinal cord and a comparative atlas of both rat and mouse spinal cords in one convenient source. The book provides a descriptive survey of the details of mammalian spinal cord anatomy, focusing on the rat with many illustrations from the leading experts in the field and atlases of the rat and the mouse spinal cord. The rat and mouse spinal cord atlas chapters include photographs of Nissl stained transverse sections from each of the spinal cord segments (obtained from a single unfixed spinal cord), detailed diagrams of each of the spinal cord segments pictured, delineating the laminae of Rexed and all other significant neuronal groupings at each level and photographs of additional sections displaying markers such as acetylcholinesterase (AChE), calbindin, calretinin, choline acetlytransferase, neurofilament protein (SMI 32), enkephalin, calcitonin gene-related peptide (CGRP), and neuronal nuclear protein (NeuN).

  • Neurogenic Inflammation in Health and Disease

    • 1 Edición
    • Volumen 8
    • Inglés
    Morphological and functional studies revealed a complex system of primary sensory neurons that parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel that transmits pain.

  • Glaucoma: An Open-Window to Neurodegeneration and Neuroprotection

    • 1 Edición
    • Volumen 173
    • Carlo Nucci + 3 más
    • Inglés
    Glaucoma is one of the main causes of blindness throughout the world. It is characterized by death of the retinal ganglion cells, which is associated with loss of the axons making up the optic nerve. Recent studies have demonstrated support for the classification of glaucoma as a degenerative disease of the central nervous system (CNS), leading researchers to look at identifying neuroprotection strategies for the treatment of this disease, like those used for other degenerative diseases of the CNS. This book will provide an in-depth examination of the most recent findings regarding glaucoma, including risk factors, diagnosis, clinical monitoring, treatment, and above all, the need for treatment based on the concept of neuroprotection. A large part of the book is devoted to research related to this new approach to the treatment of glaucoma.

  • MATLAB for Neuroscientists

    An Introduction to Scientific Computing in MATLAB
    • 1 Edición
    • Pascal Wallisch + 5 más
    • Inglés
    MATLAB for Neuroscientists: An Introduction to Scientific Computing in MATLAB is the first comprehensive teaching resource and textbook for the teaching of MATLAB in the Neurosciences and in Psychology. MATLAB is unique in that it can be used to learn the entire empirical and experimental process, including stimulus generation, experimental control, data collection, data analysis and modeling. Thus a wide variety of computational problems can be addressed in a single programming environment. The idea is to empower advanced undergraduates and beginning graduate students by allowing them to design and implement their own analytical tools. As students advance in their research careers, they will have achieved the fluency required to understand and adapt more specialized tools as opposed to treating them as "black boxes". Virtually all computational approaches in the book are covered by using genuine experimental data that are either collected as part of the lab project or were collected in the labs of the authors, providing the casual student with the look and feel of real data. In some cases, published data from classical papers are used to illustrate important concepts, giving students a computational understanding of critically important research.

  • The Neurology of Consciousness

    Cognitive Neuroscience and Neuropathology
    • 1 Edición
    • Steven Laureys + 1 más
    • Inglés
    Understanding consciousness is the major unsolved problem in biology. One increasingly important method of studying consciousness is to study disorders of consciousness, e.g. brain damage and disease states leading to vegetative states, coma, minimally conscious states, etc. Many of these studies are very much in the public eye because of their relationship to controversies about coma patients (e.g. Terry Schiavo case in the US recently), and the relationship to one of the major philosophical, sociological, political, and religious questions of humankind.This is the first book to summarize our current understanding of the neuroanatomical and functional underpinnings of human consciousness by emphasizing a lesional approach offered via the study of neurological patients. The selected contributors are all outstanding authors and undisputed leaders in their field.

  • Concise Learning and Memory

    The Editor's Selection
    • 1 Edición
    • John H. Byrne
    • Inglés
    The study of learning and memory is a central topic in neuroscience and psychology. Many of the basic research findings are directly applicable in the treatment of diseases and aging phenomena, and have found their way into educational theory and praxis.Concise Learning and Memory represents the best 30 chapters from Learning and Memory: A comprehensive reference (Academic Press March 2008), the most comprehensive source of information about learning and memory ever assembled, selected by one of the most respective scientists in the field, John H. Byrne. This concise version provides a truly authoritative collection of overview articles representing fundamental reviews of our knowledge of this central cognitive function of animal brains. It will be an affordable and accessible reference for scientists and students in all areas of neuroscience and psychology. There is no other single-volume reference with such authority and comprehensive coverage and depth currently available.

  • Animal and Translational Models for CNS Drug Discovery: Neurological Disorders

    • 1 Edición
    • Robert A. McArthur + 1 más
    • Inglés
    Neurological Disorders is written for researchers in both academia and the pharmaceutical industry who use animal models in research and development of drugs for neurological disorders such as neurofibromatosis, Alzheimer’s disease, Parkinson’s disease, Huntington disease, ALS, and the epilepsies. Neurological Disorders has introductory chapters expressing the view of the role and relevance of animal models for drug discovery and development for the treatment of psychiatric disorders from the perspective of (a) academic basic neuroscientific research, (b) applied pharmaceutical drug discovery and development, and (c) issues of clinical trial design and regulatory agencies limitations. Each volume examines the rationale, use, robustness and limitations of animal models in each therapeutic area covered and discuss the use of animal models for target identification and validation. The clinical relevance of animal models is discussed in terms of major limitations in cross-species comparisons, clinical trial design of drug candidates, and how clinical trial endpoints could be improved. The aim of this series of volumes on Animal and Translational Models for CNS Drug Discovery is to identify and provide common endpoints between species that can serve to inform both the clinic and the bench with the information needed to accelerate clinically-effective CNS drug discovery. This is the second volume in the three volume-set, Animal and Translational Models for CNS Drug Discovery 978-0-12-373861-5, which is also available for purchase individually.

  • Serotonin-Dopamine Interaction: Experimental Evidence and Therapeutic Relevance

    • 1 Edición
    • Volumen 172
    • Giuseppe Di Giovanni + 2 más
    • Inglés
    This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and behavioral data of the serotonin (5-HT)-dopamine (DA) interactions. Central serotonergic and dopaminergic systems play a critical role in the regulation of normal and abnormal behaviors. Moreover, recent evidence suggests that the dysfunction of the DA and 5-HT neurotransmitter systems contribute to various mental disorders including depression, schizophrenia, drug addiction and Parkinson’s disease. This extremely important topic is of wide interest within the scientific community, with relevance not only to specialists but also to general practitioners and students. The book provides a valuable contribution to the debate on new pharmacological approaches for several psychopathological states, with contributions from expert neuroscientists and pharmacologists who comprehensively survey the most significant currently active areas of dopamine/serotonin interactions.

  • Epilepsy in Women

    The Scientific Basis for Clinical Management
    • 1 Edición
    • Volumen 83
    • Barry Gidal + 1 más
    • Inglés
    This volume guides the practitioner in the current management of women with epilepsy, in a comprehensive and scientifically informed manner. Many chapters are devoted to the various aspects of pregnancy management for women with epilepsy, from reducing the risks of medication exposure to breast feeding. All female age groups are discussed and chapters on issues important for adolescents and the mature women are also included. The editors have included internationally recognized experts as contributors, to bring together a body of knowledge unparalleled in previous settings. This book should be a guide to management for women with epilepsy for years to come, due to its solid scientific basis and the comprehensive vision of the contributors.

  • Puzzling Cases of Epilepsy

    • 2 Edición
    • Dieter Schmidt + 1 más
    • Inglés
    Epilepsy is one of the most common neurological disorders, and original observations in the field are often the key to diagnosis and successful treatment. Physicians new to the field as well as seasoned practitioners will benefit from more than one hundred case vignettes that explore the universe of epilepsy as it presents in daily practice. Some of these cases challenge long-held views about epilepsy and others bring the reader to the limits of our understanding of epilepsy, both in clinical and basic science. To improve the interface of clinical and basic science in epilepsy, basic scientists comment on the potential mechanisms underlying clinical observations, and clinicians assess the potential impact of recent results of experiments in the laboratory. Puzzling Cases of Epilepsy highlights the importance that original observations have in inspiring both new treatments and continued research.

  • Handbook of Episodic Memory

    • 1 Edición
    • Volumen 18
    • Ekrem Dere + 3 más
    • Inglés
    Episodic memory is the name of the kind of memory that records personal experiences instead of the mere remembering of impersonal facts and rules. This type of memory is extremely sensitive to ageing and disease so an understanding of the mechanisms of episodic memory might lead to the development of therapies suited to improve memory in some patient populations. Episodic memory is unique in that it includes an aspect of self-awareness and helps us to remember who we are in terms of what we did and what we have been passed through and what we should do in the future. This book brings together a renowned team of contributors from the fields of cognitive psychology, neuropsychology and behavioural and molecular neuroscience. It provides a detailed and comprehensive overview of recent developments in understanding human episodic memory and animal episodic-like memory in terms of concepts, methods, mechanisms, neurobiology and pathology. The work presented within this book will have a profound effect on the direction that future research in this topic will take.

  • Using Eye Movements as an Experimental Probe of Brain Function

    A Symposium in Honor of Jean Büttner-Ennever
    • 1 Edición
    • Volumen 171
    • R. John Leigh + 1 más
    • Inglés
    This volume of Progress in Brain Research is based on the proceedings of a conference, "Using Eye Movements as an Experimental Probe of Brain Function," held at the Charing Cross Hospital Campus of Imperial College London, UK on 5th -6th December, 2007 to honor Professor Jean Büttner-Ennever. With 87 contributions from international experts – both basic scientists and clinicians – the volume provides many examples of how eye movements can be used to address a broad range of research questions. Section 1 focuses on extraocular muscle, highlighting new concepts of proprioceptive control that involve even the cerebral cortex. Section 2 comprises structural, physiological, pharmacological, and computational aspects of brainstem mechanisms, and illustrates implications for disorders as diverse as opsoclonus, and congenital scoliosis with gaze palsy. Section 3 addresses how the cerebellum transforms neural signals into motor commands, and how disease of such mechanisms may lead to ataxia and disorders such as oculopalatal tremor. Section 4 deals with sensory-motor processing of visual, vestibular, somatosensory, and auditory inputs, such as are required for navigation, and gait. Section 5 illustrates how eye movements, used in conjunction with single-unit electrophysiology, functional imaging, transcranial magnetic stimulation, and lesion studies have illuminated cognitive processes, including memory, prediction, and even free will. Section 6 includes 18 papers dealing with disorders ranging from congenital to acquired forms of nystagmus, genetic and degenerative neurological disorders, and treatments for nystagmus and motion sickness.

  • The Prefrontal Cortex

    • 4 Edición
    • Joaquin Fuster
    • Joaquin Fuster
    • Inglés
    This is the fourth edition of the undisputed classic on the prefrontal cortex, the principal "executive" structure of the brain. Because of its role in such cognitive functions as working memory, planning, and decision-making, the prefrontal cortex is critically involved in the organization of behavior, language, and reasoning. Prefrontal dysfunction lies at the foundation of several psychotic and neurodegenerative disorders, including schizophrenia and dementia.

  • Quantitative EEG, Event-Related Potentials and Neurotherapy

    • 1 Edición
    • Juri D. Kropotov
    • Inglés
    While the brain is ruled to a large extent by chemical neurotransmitters, it is also a bioelectric organ. The collective study of Quantitative ElectroEncephaloGrap... (QEEG-the conversion of brainwaves to digital form to allow for comparison between neurologically normative and dysfunctional individuals), Event Related Potentials (ERPs - electrophysiological response to stimulus) and Neurotherapy (the process of actually retraining brain processes to) offers a window into brain physiology and function via computer and statistical analyses of traditional EEG patterns, suggesting innovative approaches to the improvement of attention, anxiety, mood and behavior.The volume provides detailed description of the various EEG rhythms and ERPs, the conventional analytic methods such as spectral analysis, and the emerging method utilizing QEEG and ERPs. This research is then related back to practice and all existing approaches in the field of Neurotherapy - conventional EEG-based neurofeedback, brain-computer interface, transcranial Direct Current Stimulation, and Transcranial Magnetic Stimulation - are covered in full. While it does not offer the breadth provided by an edited work, this volume does provide a level of depth and detail that a single author can deliver, as well as giving readers insight into the personl theories of one of the preeminent leaders in the field.

  • Advances in the Study of Behavior

    • 1 Edición
    • Volumen 38
    • H. Jane Brockmann + 5 más
    • Inglés
    Advances in the Study of Behavior was initiated over 40 years ago to serve the increasing number of scientists engaged in the study of animal behavior. That number is still expanding. This volume makes another important "contribution to the development of the field" by presenting theoretical ideas and research to those studying animal behavior and to their colleagues in neighboring fields. Advances in the Study of Behavior is now available online at ScienceDirect — full-text online from volume 30 onward.

  • Handbook of Cognitive Science

    An Embodied Approach
    • 1 Edición
    • Paco Calvo + 1 más
    • Inglés
    The Handbook of Cognitive Science provides an overview of recent developments in cognition research, relying upon non-classical approaches. Cognition is explained as the continuous interplay between brain, body, and environment, without relying on classical notions of computations and representation to explain cognition. The handbook serves as a valuable companion for readers interested in foundational aspects of cognitive science, and neuroscience and the philosophy of mind. The handbook begins with an introduction to embodied cognitive science, and then breaks up the chapters into separate sections on conceptual issues, formal approaches, embodiment in perception and action, embodiment from an artificial perspective, embodied meaning, and emotion and consciousness. Contributors to the book represent research overviews from around the globe including the US, UK, Spain, Germany, Switzerland, France, Sweden, and the Netherlands.

  • Human Learning: Biology, Brain, and Neuroscience

    • 1 Edición
    • Volumen 139
    • Aaron S. Benjamin + 3 más
    • Inglés
    Human learning is studied in a variety of ways. Motor learning is often studied separately from verbal learning. Studies may delve into anatomy vs function, may view behavioral outcomes or look discretely at the molecular and cellular level of learning. All have merit but they are dispersed across a wide literature and rarely are the findings integrated and synthesized in a meaningful way. Human Learning: Biology, Brain, and Neuroscience synthesizes findings across these levels and types of learning and memory investigation.Divide... into three sections, each section includes a discussion by the editors integrating themes and ideas that emerge across the chapters within each section. Section 1 discusses general topics in human learning and cognition research, including inhibition, short term and long term memory, verbal memory, memory disruption, and scheduling and learning. Section 2 discusses cognitive neuroscience aspects of human learning. Coverage here includes models, skill acquisition, declarative and non declarative memory, age effects on memory, and memory for emotional events. Section 3 focuses on human motor learning.This book is suitable for cognitive neuroscientists, cognitive psychologists, kinesthesiologists, and graduate courses in learning.

  • Animal Models in Eye Research

    • 1 Edición
    • Panagiotis Antonios Tsonis
    • Inglés
    The eye is a complex sensory organ, which enables visual perception of the world. Thus the eye has several tissues that do different tasks. One of the most basic aspects of eye function is the sensitivity of cells to light and its transduction though the optic nerve to the brain. Different organisms use different ways to achieve these tasks. In this sense, eye function becomes a very important evolutionary aspect as well. This book presents the different animal models that are commonly used for eye research and their uniqueness in evaluating different aspects of eye development, evolution, physiology and disease.

  • The Senses: A Comprehensive Reference, Volume 5

    • 1 Edición
    • Allan I. Basbaum + 3 más
    • Inglés
    This book presents the most current scientific understanding behind most common pain disorders. Clinical scientists involved in pain science will gain a basic understanding of the causes of many types of pain and will be able to discuss various therapies with patients. Researchers new to pain science will gain an overall understanding of pain pathophysiology and targets for pain treatments. Covering every major aspect of pain science, from molecular and cellular pathways of pain to pain disorders and their treatments, Science of Pain bridges basic and clinical research like no other book on the topic. Edited by world-renowned pain scientist and Editor-in-Chief of the journal PAIN, Allan Basbaum, this book is an in-depth reference for basic and clinical scientists in pain research who must understand the basic science of pain, and help develop new treatment strategies for pain disorders.

  • Neuromuscular Junction Disorders

    • 1 Edición
    • Volumen 91
    • A. G. Engel
    • Inglés
    This volume provides concise and comprehensive information on neuromuscular disorders, including rapid advancements in the understanding of the neurobiology of neuromuscular transmission. In addition, clinicians will find timely discussions on the various forms of these disorders that have been discovered due to increased study within the field. New observations into the immunopathogenesis of myasthenia gravis, and the molecular mechanisms underlying the links between activity and patterns of gene expression, particularly in muscle, are also explored, along with novel information on the understanding of the pathophysiology of the heterogeneous group of peripheral nerve hyperexcitability syndromes. Each of these valuable insights, and their accompanying explanations, provides a framework on which new therapeutic strategies can be built to aid in the enhancement and restoration of normal function in neuromuscular junction disorders.

  • Advances in Vasopressin and Oxytocin - From Genes to Behaviour to Disease

    • 1 Edición
    • Volumen 170
    • Rainer Landgraf + 1 más
    • Inglés
    Vasopressin and oxytocin are the key hormones of the hypothalamo-neurohyp... system, and are well-known to be critically involved in antidiuresis, labor, and milk ejection. This book highlights the latest research on vasopressin and oxytocin, covering multiple biological aspects. The capacity of both hormones to regulate various aspects of social behaviours including pair-bonding, aggression, maternal love, and sexual behaviour, is a main focus, as are their interactions with a variety of other neuromodulators and transmitters. Moreover, the book illustrates the recent development of vasopressin and oxytocin agonists/antagonists as potential drugs to treat not only disturbances of body fluid homeostasis, but also mental disorders, including social phobia, autism, anxiety, and depression. The promising combination of basic and clinical research, comprising physiology, neuroendocrinology, behavioral biology, pharmacology, imaging and molecular genetics makes this book an essential addition to both experts and scientists new to the field alike.

  • Neurobiology of the Parental Brain

    • 1 Edición
    • Robert Bridges
    • Inglés
    This book presents cutting edge research on the basic neurobiology of parental behavior as it relates to behavioral disorders, including postpartum depression, anxiety, and inadequate parental bonding to infants. Internationally recognized basic and clinical researchers present new research findings in humans and animals that elucidate the roles of the brain, physiological state, genes and environment in maternal and paternal care. By bridging the gap between basic and clinical research, new understandings of how the biology of the brain and the reproductive state of the parent impact their mental health and the successful rearing of young emerge.

  • The Hypothalamus-Pituitary-Adrenal Axis

    • 1 Edición
    • Volumen 7
    • Inglés
    The hypothalamic-pituita... axis controls reactions to stress and regulates various body processes such as digestion, the immune system, mood and sexuality, and energy usage. This volume focuses on the role it plays in the immune system and provides substantive experimental and clinical data to support current understanding in the field, and potential applications of this knowledge in the treatment of disease.

  • Psychiatric Controversies in Epilepsy

    • 1 Edición
    • Andres Kanner + 1 más
    • Inglés
    Psychiatric Controversies in Epilepsy addresses controversial clinical issues of the psychiatric aspects of epilepsy. The book explores the reasons behind the poor communication between psychiatrists and neurologists and suggests potential remedies to this important problem, and two chapters are devoted to examining whether psychiatrists and neurologists are properly trained to recognize and treat conditions that both disciplines commonly encounter in clinical practice. Identification of the causes behind the high rate of comorbidity between epilepsy and mood, anxiety, psychotic and attention deficit disorders is given high priority in the volume, and a specific review of the evidence of common pathogenic mechanisms that may be operant in epilepsy and these psychiatric disorders is included. Recently identified bidirectional relationship between mood disorders and epilepsy and its implication in the course and response to treatment of the seizure disorder are also explored. Several chapters are devoted to rectify common misunderstandings of the use of psychotropic drugs in patients with epilepsy, including the use of antidepressant and central nervous system stimulants. Finally, one chapter explores the possibility of organic causes of psychogenic non-epileptic seizures.

  • Mathematical Difficulties

    Psychology and Intervention
    • 1 Edición
    • Inglés
    This book examines the mathematical difficulties in typical and atypical populations. It discusses the behavioural, educational and neuropsychological characteristics of people with mathematical difficulties, and educational interventions to prevent, diagnose, treat or ameliorate such difficulties. The book brings together studies from different disciplines, including developmental psychology, neuroscience and education, and includes perspectives from practicing teachers.The book is divided into three major sections. The first includes chapters about the nature and characteristics of mathematical difficulties in the population as a whole, in relation to both psychology and education. The second deals with mathematical difficulties in children with other problems such as specific language impairment and dyslexia. The third discusses methods of interventions aimed at preventing, treating or ameliorating mathematical difficulties, and will include discussions of assessment and diagnosis.

  • Dementias

    • 1 Edición
    • Volumen 89
    • Charles Duyckaerts + 1 más
    • Inglés
    This volume provides a comprehensive understanding of the biology of dementias, including information on advancements in the way these disorders are perceived and studied. From earlier assumptions that cognitive deficits were simply age related, this handbook progresses into complex discussions of the diseases that affect the cortex of the human brain. Clinicians will find extensive diagnostic and research perspectives on a variety of interesting topics, including neuropathology, physiopathology, biology, clinics, and imaging information on all, or most, of the dementing disorders currently known. In addition, chapters devoted to legal and ethical issues give practitioners and health care workers an informative view on complex dementias and the way these disorders affect patients and families. Clinicians in all levels of expertise will find useful and synthetic information.

  • Disorders of Consciousness

    • 1 Edición
    • Volumen 90
    • G. Bryan Young + 1 más
    • Inglés
    This volume encompasses a variety of topics pertaining to patients with altered levels of consciousness, including valuable differences between disorders. Neurologists, researchers, and clinicians will find a comprehensive accounting of the distinctions between disorders that cause these altered states. Beginning with basic concepts of consciousness and neurobiology, this handbook progresses into more targeted and complex areas of discussion, including important technological advancements that have occurred in neuroimaging. Neurologists who are frequently called upon for prognostication and to guide management of patients with these disorders will find invaluable information, including chapters discussing comatose states in children and pregnant women, encephalopathic patients, nutrition disorders, and vegetative and minimally conscious states. In addition, chapters devoted to philosophical backgrounds and ethical implications involving patients with impaired consciousness, are thoroughly presented.

Temas relacionados