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Elsevier

Libros en Neurociencia

  • Emission Tomography

    The Fundamentals of PET and SPECT
    • 1 Edición
    • Miles N. Wernick + 1 más
    • Inglés
    PET and SPECT are two of today’s most important medical-imaging methods, providing images that reveal subtle information about physiological processes in humans and animals. Emission Tomography: The Fundamentals of PET and SPECT explains the physics and engineering principles of these important functional-imaging methods. The technology of emission tomography is covered in detail, including historical origins, scientific and mathematical foundations, imaging systems and their components, image reconstruction and analysis, simulation techniques, and clinical and laboratory applications. The book describes the state of the art of emission tomography, including all facets of conventional SPECT and PET, as well as contemporary topics such as iterative image reconstruction, small-animal imaging, and PET/CT systems. This book is intended as a textbook and reference resource for graduate students, researchers, medical physicists, biomedical engineers, and professional engineers and physicists in the medical-imaging industry. Thorough tutorials of fundamental and advanced topics are presented by dozens of the leading researchers in PET and SPECT. SPECT has long been a mainstay of clinical imaging, and PET is now one of the world’s fastest growing medical imaging techniques, owing to its dramatic contributions to cancer imaging and other applications. Emission Tomography: The Fundamentals of PET and SPECT is an essential resource for understanding the technology of SPECT and PET, the most widely used forms of molecular imaging.

  • The Rat Brain in Stereotaxic Coordinates - The New Coronal Set

    • 5 Edición
    • George Paxinos + 1 más
    • Inglés
    The preceding editions made The Rat Brain in Stereotaxic Coordinates the second most cited book in science. This Fifth Edition is the result of years of research providing the user with the drawings of the completely new set of coronal sections, now from one rat, and with significantly improved resolution by adding a third additional section level as compared to earlier editions. Numerous new nuclei and structures also have been identified. The drawings are presented in two color, providing a much better contrast for use. The Fifth Edition continues the legacy of this major neuroscience publication and is a guide for all students and scientists who study the rat brain.

  • Development, Dynamics and Pathology of Neuronal Networks: From Molecules to Functional Circuits

    • 1 Edición
    • Volumen 147
    • J. van Pelt + 5 más
    • Inglés
    This book is about neuronal networks within the brain. With roughly 100 billion nerve cells the human brain contains about 3.2 million kilometers of 'wires' to make a million billion of connections between these nerve cells. Nerve cells exchange electrical and chemical signals through these connections and the dynamical patterns of electrical/chemical signals are the basis of all our thinking, memories, consciousness, and control of our behaviour. How do these networks develop their specific connectivity, what are the patterns of electrical activity that serve such a fundamental role in our cognitive abilities, how can it go wrong in these networks resulting in different types of brain pathologies, such as mental retardation, Alzheimer’s disease, epilepsy or schizophrenia? These questions are among the most fundamental ones in neuroscience and are addressed in this volume. The chapters in this book cover both state-of-the-art broad reviews and in-depth studies of topics selected in order to bridge different levels of neurobiological organization, from the molecular, cellular, neural network to the cognitive level. An excellent example of such a 'red thread' is given by the chapters devoted to the visual system, illustrating the advanced state of understanding of network development, plasticity and functioning of the visual system. Other chapters illustrate how scientific advances are driven by technical developments as shown for multi-electrode recording and life imaging techniques that enable the study of electrical activity simultaneously in many nerve cells.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 62
    • Ronald J. Bradley + 2 más
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

  • From Neuroscience to Neurology

    Neuroscience, Molecular Medicine, and the Therapeutic Transformation of Neurology
    • 1 Edición
    • Stephen Waxman
    • Inglés
    The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson’s disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders.

  • DNA Arrays in Neurobiology

    • 1 Edición
    • Volumen 60
    • Inglés
    DNA array technology is a technique for studying gene expression by comparing samples of different genes. The result is an enormous amount of data that must be carefully analyzed in order for it to be useful and meaningful. This book examines both data analysis and techniques for ensuring optimal experimental conditions. The array approach has applications in a number of model systems, including development, learning and drug abuse. In addition, the technique has applications in a number of neurological disorders such as Alzheimer's disease, schizophrenia, multiple sclerosis, and neurological cancers.

  • Principles of Hormone/Behavior Relations

    • 1 Edición
    • Donald W. Pfaff + 2 más
    • Inglés
    This text introduces underlying principles of the endocrine regulation of behavior in animals and humans. Every chapter begins by stating a principle, followed by specific examples of hormone actions derived from scientific experiments and clinical observations, and concludes with a few challenging unanswered questions. The reference source Hormones, Brain & Behavior identified this field as rapidly expanding within neurobiology and endocrinology. Now, this well-illustrated and referenced text will serve students from undergraduate school to medical school as they learn this new discipline.

  • Introduction to Psychoneuroimmunology

    • 1 Edición
    • Jorge H. Daruna
    • Inglés
    Psychoneuroimmunolog... investigates the relationships between behavior, psychosocial factors, the nervous, endocrine, and immune systems, and disease. Each system affects the others, enhancing and/or inhibiting processes elsewhere in the body. Research in this field has grown tremendously in recent years as science better understands the checks and balances of these interdisciplinary systems and processes. Introduction to Psychoneuroimmunolog... provides the first introductory text for this complex field.Beginning with a discussion of immune system basics, Introduction to Psychoneuroimmunolog... explores endocrine-immune modulation, neuro-immune modulation, the relationship between stress, contextual change, and disease, as well as infection, allergy, immune activity and psychopathology, and immune function enhancement. This text provides a sound introduction to the field and will serve as a valuable overview to what is otherwise a complex interdisciplinary subject at the junction of molecular biology, genetics, the neurosciences, immunology, cell biology, endocrinology, pharmacology, biochemistry, and the behavioral sciences.

  • The Neuroendocrine Immune Network in Ageing

    • 1 Edición
    • Volumen 4
    • R.H. Straub + 1 más
    • Inglés
    The book describes the mechanisms involved in the maintenance of neuroendocrine-immun... interactions in ageing. The lack of this maintenance leads to the appearance of age-related diseases (cancer, infections, dementia) and subsequent disability. The capacity of some hormones or nutritional factors in restoring and remodelling the neuroendocrine-immun... response during ageing is reported presenting possible new anti-ageing strategies in order to reach healthy ageing and longevity.

  • Representation in Mind

    New Approaches to Mental Representation
    • 1 Edición
    • Volumen 1
    • Hugh Clapin + 2 más
    • Inglés
    'Representation in Mind' is the first book in the new series 'Perspectives on Cognitive Science' and includes well known contributors in the areas of philosophy of mind, psychology and cognitive science.The papers in this volume offer new ideas, fresh approaches and new criticisms of old ideas. The papers deal in new ways with fundamental questions concerning the problem of mental representation that one contributor, Robert Cummins, has described as "THE problem in philosophy of mind for some time now". The editors' introductory overview considers the problem for which mental representation has been seen as an answer, sketching an influential framework, outlining some of the issues addressed and then providing an overview of the papers. Issues include: the relation between mental representation and public, non-mental representation; misrepresentation; the role of mental representations in intelligent action; the relation between representation and consciousness; the relation between folk psychology and explanations invoking mental representations

  • Neuromimetic Semantics

    Coordination, quantification, and collective predicates
    • 1 Edición
    • Harry Howard
    • Inglés
    This book attempts to marry truth-conditional semantics with cognitive linguistics in the church of computational neuroscience. To this end, it examines the truth-conditional meanings of coordinators, quantifiers, and collective predicates as neurophysiological phenomena that are amenable to a neurocomputational analysis. Drawing inspiration from work on visual processing, and especially the simple/complex cell distinction in early vision (V1), we claim that a similar two-layer architecture is sufficient to learn the truth-conditional meanings of the logical coordinators and logical quantifiers. As a prerequisite, much discussion is given over to what a neurologically plausible representation of the meanings of these items would look like. We eventually settle on a representation in terms of correlation, so that, for instance, the semantic input to the universal operators (e.g. and, all)is represented as maximally correlated, while the semantic input to the universal negative operators (e.g. nor, no)is represented as maximally anticorrelated. On the basis this representation, the hypothesis can be offered that the function of the logical operators is to extract an invariant feature from natural situations, that of degree of correlation between parts of the situation. This result sets up an elegant formal analogy to recent models of visual processing, which argue that the function of early vision is to reduce the redundancy inherent in natural images. Computational simulations are designed in which the logical operators are learned by associating their phonological form with some degree of correlation in the inputs, so that the overall function of the system is as a simple kind of pattern recognition. Several learning rules are assayed, especially those of the Hebbian sort, which are the ones with the most neurological support. Learning vector quantization (LVQ) is shown to be a perspicuous and efficient means of learning the patterns that are of interest. We draw a formal parallelism between the initial, competitive layer of LVQ and the simple cell layer in V1, and between the final, linear layer of LVQ and the complex cell layer in V1, in that the initial layers are both selective, while the final layers both generalize. It is also shown how the representations argued for can be used to draw the traditionally-recogn... inferences arising from coordination and quantification, and why the inference of subalternacy breaks down for collective predicates. Finally, the analogies between early vision and the logical operators allow us to advance the claim of cognitive linguistics that language is not processed by proprietary algorithms, but rather by algorithms that are general to the entire brain. Thus in the debate between objectivist and experiential metaphysics, this book falls squarely into the camp of the latter. Yet it does so by means of a rigorous formal, mathematical, and neurological exposition – in contradiction of the experiential claim that formal analysis has no place in the understanding of cognition. To make our own counter-claim as explicit as possible, we present a sketch of the LVQ structure in terms of mereotopology, in which the initial layer of the network performs topological operations, while the final layer performs mereological operations. The book is meant to be self-contained, in the sense that it does not assume any prior knowledge of any of the many areas that are touched upon. It therefore contains mini-summaries of biological visual processing, especially the retinocortical and ventral /what?/ parvocellular pathways; computational models of neural signaling, and in particular the reduction of the Hodgkin-Huxley equations to the connectionist and integrate-and-fire neurons; Hebbian learning rules and the elaboration of learning vector quantization; the linguistic pathway in the left hemisphere; memory and the hippocampus; truth-conditional vs. image-schematic semantics; objectivist vs. experiential metaphysics; and mereotopology. All of the simulations are implemented in MATLAB, and the code is available from the book’s website.

  • Time-to-Contact

    • 1 Edición
    • Volumen 135
    • Heiko Hecht + 1 más
    • Inglés
    Time-to-contact is the visual information that observers use in fundamental tasks such as landing an airplane or hitting a ball. Time-to-contact has been a hot topic in perception and action for many years and although many articles have been published on this topic, a comprehensive overview or assessment of the theory does not yet exist. This book fills an important gap and will have appeal to the perception and action community. The book is divided into four sections. Section one covers the foundation of time-to-contact, Section two covers different behavioral approaches to time-to-contact estimation, Section three focuses on time-to-contact as perception and strategy, and Section four covers time-to-contact and action regulation.

  • Primer on the Autonomic Nervous System

    • 2 Edición
    • Phillip A. Low
    • Inglés
    The Primer on the Autonomic Nervous System presents, in a readable and accessible format, key information about how the autonomic nervous system controls the body, particularly in response to stress. It represents the largest collection of world-wide autonomic nervous system authorities ever assembled in one book. It is especially suitable for students, scientists and physicians seeking key information about all aspects of autonomic physiology and pathology in one convenient source. Providing up-to-date knowledge about basic and clinical autonomic neuroscience in a format designed to make learning easy and fun, this book is a must-have for any neuroscientist’s bookshelf!

  • The Rat Nervous System

    • 3 Edición
    • George Paxinos
    • Inglés
    This third edition of the standard reference on the nervous system of the rat is a complete and updated revision of the 1994 second edition. All chapters have been extensively updated, and new chapters added covering early segmentation, growth factors, and glia. The book is now aligned with the data available in the Rat Brain in Stereotaxic Coordinates, making it an excellent companion to this bestselling atlas. Physiological data, functional concepts, and correlates to human anatomy and function round out the new edition.

  • Disorders of Synaptic Plasticity and Schizophrenia

    • 1 Edición
    • Volumen 59
    • Inglés
    Schizophrenia is a severe brain disorder that affects 1% of the population. Its cause is due to the interaction of a number of abnormal genes with environmental factors. This book summarizes new advances schizophrenia research that focus on the field of neural and synaptic plasticity. Synapses in the brain in schizophrenia show a wide range of disorders, both structural and functional. This volume covers the most active and promising of these new developments, and opens up new avenues for the treatment of schizophrenia.

  • EMG Pearls

    • 1 Edición
    • Anthony A. Amato + 1 más
    • Inglés
    This title in the popular Pearls Series focuses on electrodiagnostic studies of neuromuscular diseases. EMGs and their interpretation are a major component of the specialty of physical medicine and rehab physicians, and they are important to neurologists and electromyographers. For each case, patient information is presented, the EMG findings are discussed, and the reader is asked to make a diagnosis based on these findings. The next page reveals the diagnosis, discussed the case and the medical condition in question, and then presents 3-4 pearls of practice distilled from the case.

  • The Psychology of Learning and Motivation

    Advances in Research and Theory
    • 1 Edición
    • Volumen 44
    • Inglés
    The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter provides a thoughtful integration of a body of work.

  • Human Hypothalamus: Basic and Clinical Aspects, Part II

    • 1 Edición
    • Volumen 80
    • Dick F. Swaab
    • Inglés
    This volume provides a comprehensive understanding of the human hypothalamus, an extremely complex structure that consists of a large number of very different functional units. It approaches the subject in a way that has not historically existed in standard neuropathological investigations of the human brain. As the hypothalamus was traditionally considered to be a neuroendocrine structure, and hence of little interest to neurologists, this volume explores new findings in the field and the value they bring to the field of neurology. New understandings of the role the hypothalamus plays in memory and attention deficits in the dementias, along with greater evidence that the hypothalamus is related to symptoms and signs in both neurological and psychological disorders provide users in the fields of neuroscience, endocrinology, pediatrics, and psychology with a comprehensive resource on which to base new research and exploration.

  • The Human Nervous System

    • 2 Edición
    • George Paxinos + 1 más
    • Inglés
    This long-awaited update of the classic, The Human Nervous System, stands as an impressive survey of our knowledge of the brain, spinal cord, and peripheral nervous system. The book has been completely redone and brought up-to-date. An impressive and respected cast of international authors have contributed 37 chapters on topics ranging from Brain Evolution, all phases of Brain Development, to all areas of the adult brain and peripheral pathways, along with careful descriptions of the spinal cord and peripheral nervous system, brainstem and cerebellum. The Human Nervous System, Second Edition will again serve as the gold standard, providing a one-stop source of up-to-date information about our knowledge of the human nervous system.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 57
    • Ronald J. Bradley + 2 más
    • Inglés
    International Review of Neurobiology is a well-respected series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a cumulative subject index of volumes 1-25.

  • Advances in the Study of Behavior

    • 1 Edición
    • Volumen 33
    • Peter J.B. Slater + 4 más
    • Inglés
    The aim of Advances in the Study of Behavior remains as it has been since the series began: to serve the increasing number of scientists who are engaged in the study of animal behavior by presenting their theoretical ideas and research to their colleagues and to those in neighboring fields. We hope that the series will continue its "contribution to the development of the field", as its intended role was phrased in the Preface to the first volume in 1965. Since that time, traditional areas of animal behavior have achieved new vigor by the links they have formed with related fields and by the closer relationship that now exists between those studying animal and human subjects.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 58
    • Ronald J. Bradley + 2 más
    • Inglés
    International Review of Neurobiology is a well-respected series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a cumulative subject index of volumes 26-50.

  • Human Hypothalamus: Basic and Clinical Aspects, Part I

    • 1 Edición
    • Volumen 79
    • Dick F. Swaab
    • Inglés
    As the human hypothalamus has traditionally been considered part of the neuroendocrine system, it has been of little interest to neurologists. This volume creates renewed interest in the subject, highlighting groundbreaking research that links this complex part of the human brain to a variety of neurological and psychological disorders. Clinicians, researchers, and practitioners from a variety of medical fields will find this to be a comprehensive presentation of new research that applies to a variety of disorders, including their origin, diagnosis, and treatment. From groundbreaking discussions that link the human hypothalamus to attention deficits in the dementias, to its role in disorders such as narcolepsy and certain epilepsies, users will find this volume to be an invaluable resource for research and patient care. Specific information on topics including depression, eating disorders, aggression, and mental retardation are included, giving those in the field of neurology, psychiatry, endocrinology, and pediatrics a comprehensive understanding on how the human hypothalamus is related to patient disorders in these fields.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 56
    • Ronald J. Bradley + 2 más
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of articles covering recent advances in the field of neurobiology. Topics covered include behavioral mechanisms and the neurobiology of conditioned sexual responding; NMDA receptors in alcoholism; processing and representation of species-specific communication calls in the auditory system of bats; central nervous system control of micturition; the structure and physiology of the rat auditory system; and neurobiology of cat and human sexual behavior.

  • NGF and Related Molecules in Health and Disease

    • 1 Edición
    • Volumen 146
    • L. Aloe + 1 más
    • Inglés
    The book highlights different aspects of current understanding of neurotrophin-recepto... signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-asso... activity of NGF and/or BDNF are also presented and discussed. Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins play important roles in the pathobiology of a surprising variety of seemingly unrelated non-neurological diseases, including bronchial asthma, rheumatoid arthritis, systemic sclerosis, hair growth disorders, psoriasis, corneal and skin ulcers, atherosclerosis, metabolic syndrome, crush syndrome, and Behçet's disease. There are also chapters on the involvement of NGF and related molecules in neurological diseases, including Huntington's disease, the multiple sclerosis-like model of experimental allergic encephalomyelitis, peripheral neuropathies, neuroblastoma, Parkinson's disease, Alzheimer's disease, and even motion sickness syndrome, also psychiatric disorders, including depression and schizophrenia. Finally, potential important therapeutic benefits are presented, for diabetic neuropathy, gastrointestinal dysmotility, CNS neurodegenerative disease, spinal cord injuries, cutaneous and corneal ulcers, as well as peripheral ischemic vasculopathy.

  • Development of Auditory and Vestibular Systems-3: Molecular Development of the Inner Ear

    • 1 Edición
    • Volumen 57
    • Raymond Romand + 1 más
    • Inglés
    Thanks to advances in genetics and genomics, research on inner ear development has flourished. Better approaches and experimental models have shed light on the function of a variety of vertebrate genes and their related proteins. This latest volume of Current Topics in Developmental Biology delves into this new research to show how the discovery of more genes involved in the development of the inner ear leads to the generation of new models that examine a wealth of issues -- from the origins of human deafness to the roles of genes during inner ear induction, development and differentiation. The wide variety of experimental approaches will help readers to understand the broad range of issues related to inner ear morphogenesis and other concepts from complementary areas of investigation. This state-of-the-art overview will be essential reading for researchers, clinicians and students alike.

  • Blood-Spinal Cord and Brain Barriers in Health and Disease

    • 1 Edición
    • Hari Shanker Sharma
    • Hari Shanker Sharma
    • Inglés
    Recent research into the anatomy and pathophysiology of the blood-brain and blood-spinal cord barriers suggests that a breakdown in these barriers can result in several diseases affecting the central nervous system (CNS). This book presents new findings in the area of blood-brain barrier research that suggest barriers play important roles in health and disease conditions. It also discusses the development of new drugs that can modulate the barrier function in the CNS and may provide new approaches to treating neurological diseases such as Alzheimer's disease and other motor neuron diseases, as well as spinal cord trauma.

  • Advances in Insect Physiology

    • 1 Edición
    • Volumen 31
    • Inglés
    Advances in Insect Physiology publishes eclectic volumes containing important, comprehensive and in-depth reviews on all aspects of insect physiology. It is an essential reference source for invertebrate physiologists and neurobiologists, entomologists, zoologists and insect biochemists. First published in 1963, the serial is now edited by Steve Simpson (Oxford University, UK). In 2002, the Institute for Scientific Information released figures showing that Advances in Insect Physiology has an Impact Factor of 3, placing it 2nd in the highly competitive category of Entomology. Volume 31 contains four timely reviews, including an important contribution on insect neurobiology.

  • From Molecules to Networks

    An Introduction to Cellular and Molecular Neuroscience
    • 1 Edición
    • John H. Byrne + 3 más
    • Inglés
    An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. This book provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells that is needed by advanced undergraduates and graduate students, as well as researchers in need of a thorough reference.

  • Acetylcholine in the Cerebral Cortex

    • 1 Edición
    • Volumen 145
    • L. Descarries + 2 más
    • Inglés
    Comprehensive exposé, by leading neuroscientists, of current knowledge on the neurotransmitter acetylcholine in the cerebral cortex. All aspects of the subject are covered, from its most elementary, at the molecular and cellular levels, to its systemic and holistic implications, including its role in cognition and involvement in human diseases and therapeutics. The twenty-two chapters are grouped under four main headings : I. Functional Morphology of the Acetylcholine Innervation in Cerebral Cortex (Including Hippocampus); II. Modes of Action of Acetylcholine in the Cerebral Cortex; III. Cortical Properties and Functions Modulated by Acetylcholine, and IV. Clinical, Pathological and Therapeutic Implications. This broad perspective updates the reader on recent advances and future trends in the study of a major neuromodulatory system in brain.

  • Brain Mechanisms for the Integration of Posture and Movement

    • 1 Edición
    • Volumen 143
    • Inglés

  • Mechanisms of Memory

    • 1 Edición
    • J. David Sweatt
    • J. David Sweatt
    • Inglés
    This book stands as the first unified overview of the cellular and molecular mechanisms underlying higher-order learning and memory. It integrates modern discoveries concerning learning and memory disorders such as mental retardation syndromes and Alzheimer's Disease, while also emphasizing the results gained from the cutting-edge research methodologies of genetic engineering, complex behavioral characterization, proteomics, and molecular biology. This book provides a foundation of experimental design that will be useful to all students pursuing an interest in laboratory research. This book is an enlightening and invaluable resource for anyone concerned with memory mechanisms.

  • Visions: Artists Living with Epilepsy

    • 1 Edición
    • Steven C. Schachter
    • Inglés
    Visions: Artists Living with Epilepsy is the art of epilepsy, captured in a book. You will discover beautiful, insightful, haunting images that reveal the souls of artists touched by epilepsy.

  • Glial Cell Function (Paperback)

    • 1 Edición
    • B. Castellano Lopez + 1 más
    • Inglés
    Although knowledge of the development and differentiation of glial cells has significantly increased in recent years, there are still many questions unanswered. The first section of the book is devoted to this very active topic and includes contributions on Schwann cells, oligodendrocytes, astroglia and microglia.The second section of the book covers cellular interactions, the role they play on myelination and remyelination, how these interactions take place and the molecules involved.The third section of this volume focuses on the interactions of neurons with glial cells and their role in brain function. Neuron-glia cross talk appears to be fundamental for synaptic transmission and several chapters in this section address this topic. The topic of how glial cells react to brain injury and how they participate in neuroprotection and brain repair is covered in section four of this book. As our knowledge about the molecules involved in the regenerative properties of glia increases, new avenues are open for the use of genetically modified glia with therapeutic purposes.The final section of the book is devoted to therapeutic approaches to tumours, viral and prion infections. Gene therapy is a promising approach for the treatment of gliomas, one of the most devastating forms of cancer. A chapter on prion diseases and microglia addresses a question of tremendous actuality, since prion diseases in cows is at this moment the major veterinary problem in Europe and has created a considerable social alarm.

  • Viral Vectors for Treating Diseases of the Nervous System

    • 1 Edición
    • Volumen 55
    • David S. Latchman
    • Inglés
    Gene therapy offers considerable potential for the treatment of various incurable diseases of the nervous system. Viral Vectors for Treating Disease of the Nervous System describes a number of different viral vectors developed for achieving high efficiency gene delivery to the brain. Vectors described include those based on adenovirus, adeno-associated virus, Herpes Simplex Virus, lentivirus, and other retroviruses. It also discusses the potential application of such viruses in treating brain tumors, Parkinson's disease, and other diseases of the nervous system.

  • The Immune-Neuroendocrine Circuitry

    History and Progress
    • 1 Edición
    • Volumen 3
    • I. Berczi + 1 más
    • Inglés
    The book summarises the current understanding of the Nervous -, Endocrine and Immune systems with emphasis on shared mediators and receptors and functional interaction. In addition to the fundamental physiological and pathophysiological mechanisms, which are presented in detail, some clinically relevant subjects are also presented, such as inflammation, asthma and allergy, autoimmune disease, immunodeficiency and the acute phase response. • A comprehensive presentation of neuroimmune biology• Introduces the subject matter to the uninformed reader• Contains basic information, theoretical considerations and up-to-date clinical chapters• The clinical chapters will be helpful to practising physicians

  • The Science of Color

    • 2 Edición
    • Steven K. Shevell
    • Inglés
    The Science of Color focuses on the principles and observations that are foundations of modern color science. Written for a general scientific audience, the book broadly covers essential topics in the interdisciplinary field of color, drawing from physics, physiology and psychology. This book comprises eight chapters and begins by tracing scientific thinking about color since the seventeenth century. This historical perspective provides an introduction to the fundamental questions in color science, by following advances as well as misconceptions over more than 300 years. The next chapters then discuss the relationship between light, the retinal image, and photoreceptors, followed by a focus on concepts such as color matching and color discrimination; color appearance and color difference specification; the physiology of color vision; the 15 mechanisms of the physics and chemistry of color; and digital color reproduction. Each chapter begins with a short outline that summarizes the organization and breadth of its material. The outlines are valuable guides to chapter structure, and worth scanning even by readers who may not care to go through a chapter from start to finish. This book will be of interest to scientists, artists, manufacturers, and students.

  • Neurons: Methods and Applications for the Cell Biologist

    • 1 Edición
    • Volumen 71
    • Inglés
    Neurons: Methods and Applications for the Cell Biologist lays out numerous simple techniques for growing and carrying out experiments with many varieties of neurons. Subjects include peripheral and central neurons from vertebrate and invertebrate sources, as well as neuron-like cell lines. It also explains recent advances in our ability to introduce exogenous proteins and genes to neurons in culture. Procedures for successful protein infiltration, biolistic transfection, electroporation, and viral transgenic methods in neurons are also presented.

  • Computational Neuroscience: Trends in Research 2003

    • 1 Edición
    • E. De Schutter
    • Inglés
    This volume includes papers originally presented at the 11th annual Computational Neuroscience Meeting (CNS 02) held in July 2002 at the Congress Plaza Hotel & Convention Center in Chicago, Illinois, USA.The CNS meetings bring together computational neuroscientists representing many different fields and backgrounds as well as many different experimental preparations and theoretical approaches. The papers published here range from pure experimental neurobiology, to neuro-ethology, mathematics, physics, and engineering. In all cases the research described is focused on understanding how nervous systems compute. The actual subjects of the research include a highly diverse number of preparations, modeling approaches and analysis techniques. Accordingly, this volume reflects the breadth and depth of current research in computational neuroscience taking place throughout the world.

  • Psychology of Learning and Motivation

    • 1 Edición
    • Volumen 43
    • Inglés
    The Psychology of Learning and Motivation publishes empirical and theoretical contributions in cognitive and experimental psychology, ranging from classical and instrumental conditioning to complex learning and problem solving. Each chapter provides a thoughtful integration of a body of work.

  • The Mind's Eye

    Cognitive and Applied Aspects of Eye Movement Research
    • 1 Edición
    • Ralph Radach + 2 más
    • Inglés
    The book provides a comprehensive state-of-the-art overview of current research on cognitive and applied aspects of eye movements. The contents include peer-reviewed chapters based on a selection of papers presented at the 11th European Conference on Eye Movements (Turku, Finland 2001), supplemented by invited contributions. The ECEM conference series brings together researchers from various disciplines with an interest to use eye-tracking to study perceptual and higher order cognitive functions. The contents of the book faithfully reflect the scope and diversity of interest in eye-tracking as a fruitful tool both in basic and applied research. It consists of five sections: visual information processing and saccadic eye movements; empirical studies of reading and language production; computational models of eye movements in reading; eye-tracking as a tool to study human-computer interaction; and eye movement applications in media and communication research. Each section is concluded by a commentary chapter by one of the leading authorities in the field. These commentaries discuss and integrate the contributions in the section and provide an expert view on the most significant present and future developments in the respective areas. The book is a reference volume including a large body of new empirical work but also principal theoretical viewpoints of leading research groups in the field.

  • Cognitive Vision

    Psychology of Learning and Motivation
    • 1 Edición
    • Volumen 42
    • Inglés
    Use of visual information is used to augment our knowledge, decide on our actions, and keep track of our environment. Even with eyes closed, people can remember visual and spatial representations, manipulate them, and make decisions about them. The chapters in Volume 42 of Psychology of Learning and Motivation discuss the ways cognition interacts with visual processes and visual representations, with coverage of figure-ground assignment, spatial and visual working memory, object identification and visual search, spatial navigation, and visual attention.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 54
    • Ronald J. Bradley + 2 más
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume is a collection of chapters covering recent advances in the field of neurobiology. Chapters address anesthetic binding sites on the nicotinic acetylcholine receptors, NMDA receptor signal regulation, alcohol self-administration in rodents, and dopamine receptor mutations in mice.

  • Advances in the Study of Behavior

    • 1 Edición
    • Volumen 32
    • Peter J.B. Slater + 3 más
    • Inglés
    The aim of Advances in the Study of Behavior remains as it has been since the series began: to serve the increasing number of scientists who are engaged in the study of animal behavior by presenting their theoretical ideas and research to their colleagues and to those in neighboring fields. We hope that the series will continue its "contribution to the development of the field", as its intended role was phrased in the Preface to the first volume in 1965. Since that time, traditional areas of animal behavior have achieved new vigor by the links they have formed with related fields and by the closer relationship that now exists between those studying animal and human subjects.

  • Boxing

    Medical Aspects
    • 1 Edición
    • Friedrich Unterharnscheidt + 1 más
    • Inglés
    This book neither argues for or against the continuation of boxing, but lays out the literature and the body of scientific knowledge that are necessary to provide a meaningful background for the ensuing debate. It provides a comprehensive resource for those who are involved in regulating boxing and those who participate directly, as well as for the medical and scientific communities. Includes carefully quoted case histories and research as well as an extensive body of medical literature on boxing injuries to demonstrate that brain damage is a natural consequence of boxing.

  • Mitochondrial Function and Dysfunction

    • 1 Edición
    • Volumen 53
    • Anthony Schapira
    • Inglés
    Mitochondria are critical to the survival of cells, therefore, it is not surprising that abnormalities in mitochondrial function may lead to human disease. This book concentrates on the biology and pathology of mitochondria, covering some ot the important basic science features of the biology of mitochondria. It then moves on to discuss the breadth of human diseases related to mitochondrial dysfunction, including Parkinson's disease, Amyotrophic Lateral Sclerosis (ALS), and Alzheimer's disease.

  • Peptide Receptors, Part II

    • 1 Edición
    • Volumen 20
    • A. Bjorklund + 2 más
    • Inglés
    Peptide Receptors Part I was published in 2000 (as volume 16 of the Handbook of Chemical Neuroanatomy series). This volume summarized current knowledge on the discrete anatomical distribution of ten families of neuropeptide receptors expressed in the mammalian CNS. Part II is its natural complementwith chapters covering six additional families of neuropeptide receptors for ligands ranging from well known peptides such as the opioids and neurotensin to recently isolated ones like the orexins. As in the case of Part I, this volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry and immunocytochemistry.... derived from transgenic and knock-out animals are also summarized, helping to decipher the possible physiological and Pathophysiological role(s) of a given peptide family. Some chapters also review current knowledge on the profile of internalization of the neuropeptide-recepto... complex, an area of intense research activities that should help to better understand mechanisms involved in desensitization and tachyphylaxis.

  • Neurobiology of the Immune System

    • 1 Edición
    • Volumen 52
    • Angela Clow + 1 más
    • Inglés
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

  • Gonadotropin-Releasing Hormone: Molecules and Receptors

    • 1 Edición
    • Volumen 141
    • I.S. Parhar
    • Inglés
    This volume summarizes the evolution and physiology of GnRH molecules and receptors, and provides insight as to how social behavior influences cellular and molecular events in the brain from a comparative perspective.The chapters in this volume are divided into three major sections: Development and Cell Migration, GnRH Receptors, Physiology and Regulation. The review papers arose primarily from presentations made at the Second International Symposium on the Comparative Biology of GnRH, held in Penang, Malaysia, June 2-4, 2001; a satellite symposium in conjunction with the XIV International Congress of Comparative Endocrinology, Sorrento, Italy. In addition, leading neuroscientists doing cutting-edge research in the field of GnRH were invited as authors to make this volume a valuable reference.

  • Fundamental Neuroscience

    • 2 Edición
    • Larry Squire + 9 más
    • Inglés
    With over 300 training programs in neuroscience currently in existence, demand is great for a comprehensive textbook that both introduces graduate students to the full range of neuroscience, from molecular biology to clinical science, but also assists instructors in offering an in-depth course in neuroscience to advanced undergraduates.The second edition of Fundamental Neuroscience accomplishes all this and more. The thoroughly revised text features over 25% new material including completely new chapters, illustrations, and a CD-ROM containing all the figures from the text. More concise and manageable than the previous edition, this book has been retooled to better serve its audience in the neuroscience and medical communities.

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