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Elsevier

Libros en Farmacología

  • Advances in Pharmaceutical Sciences

    • 1 Edición
    • Volumen 7
    • Inglés
    The seventh volume of Advances in Pharmaceutical Sciences heralds a welcome continuation of this well-respected series. Acknowledged experts provide comprehensive statements of current research and development in selected fields of pharmaceutical technology. This book will be of great value to those working in academia and the pharmaceutical industry.

  • Advances in Drug Research

    • 1 Edición
    • Volumen 26
    • Inglés
    Volume 26 continues the trend of shorter, more frequent volumes. With Volume 25, the series gained a new co-editor, Urs Meyer. While retaining the commitment to publish chapters on therapeutic or chemical classes and on general topics or concepts, the series' coverage has expanded to include methodological chapters, and new areas of recognized or potential significance to drug research, especially in molecular pharmacology.

  • Advances in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 63
    • Inglés
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area-one of great importance to organic chemists, polymer chemists, and many biological scientists. Every fifth volume ofAdvances in Heterocyclic Chemistry contains a cumulative subject index.

  • Chemistry and Pharmacology

    • 1 Edición
    • Volumen 46
    • Inglés
    Internationally acclaimed for more than forty years, this serial, founded by the late Professor R.H.F. Manske, continues to provide outstanding coverage of the rapidly expanding field of the chemotaxonomy, structureelucidation... synthesis, biosynthesis, and biology of all classes of alkaloids from higher and lower plants, marine organisms, or various terrestrial animals. Each volume provides, through its distinguished authors, up-to-date and detailed coverage of particular classes or sources of alkaloids. Over the years, this series has become the standard in natural product chemistry to which all other book series aspire. The Alkaloids: Chemistry and Pharmacology endures as an essential reference for all natural product chemists and biologists who have an interest in alkaloids, their diversity, and their unique biological profile.

  • Advances in Heterocyclic Chemistry

    • 1 Edición
    • Volumen 62
    • Inglés
    Established in 1960, Advances in Heterocyclic Chemistry is the definitive serial in the area--one of great importance to organic chemists, polymer chemists, and many biological scientists. Every fifth volume ofAdvances in Heterocyclic Chemistry contains a cumulative subject index.

  • Immunopharmacology of Free Radical Species

    • 1 Edición
    • Inglés
    Free radicals have been implicated in a entire host of different human disease states, which suggests that although they may not have a pivotal causal role, they are involved in the perpetuation of disease. In recentyears, it has become evident that although free radicals most certainly do have this role in perpetuating inflammatory reactions, they have perhaps a far more important role in acting as second messenger systems to maintain normal cell function. It is theperturbations of these reactions which pose the most intriguing therapeutic challenges. This volume deals with various basic mechanisms of free radical processes and injury. The emphasis in each case is on potential therapeutic strategies developing fromthis new knowledge.

  • Mechanisms and Models in Rheumatoid Arthritis

    • 1 Edición
    • B. Henderson + 2 más
    • Inglés
    Rheumatoid arthritis is a bewilderingly complex disease involving the interactions of many, and varied, cell populations and multiple families of low and high molecular mass mediators. We are only slowly beginning to understand the mechanisms that produce the local and systematic pathology clinically recognized as rheumatoid arthritis. Increasingly, use is being made of experimental models of this disease in an effort to test hypotheses about putative pathological mechanisms and to investigate the effect of novel therapeutic agents. A major section of this book covers these experimental models in great detail from their development through to reviews of the most recent information on each model.Mechanisms and Models in Rheumatoid Arthritis brings together a group of eminent researchers from the fields of clinical rheumatology, pathology, experimental pathology, immunology, connective tissue biochemistry, microbiology, pharmacology and developmental biology to describe the current views of the cellular and humoral mechanisms that drive the pathology of rheumatoid arthritis and experimental models of rheumatoid arthritis.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 36
    • Inglés
    Published since 1959, this serial presents in-depth reviews on key topics in neuroscience, from molecules to behavior. The serial stays keenly attuned to recent developments in the field through the contributions offirst-class experts. Neuroscientists as well as clinicians, psychologists, physiologists, and pharmacologists will find this serial an indispensable addition to their library.

  • DNA Topoisomearases: Biochemistry and Molecular Biology

    • 1 Edición
    • Volumen 29A
    • Inglés
    Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

  • Advances in Pharmacology

    • 1 Edición
    • Volumen 28
    • Inglés
    Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular basis of drug action, both applied and experimental.

  • Advances in Pharmacology

    • 1 Edición
    • Volumen 25
    • Inglés

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 31
    • Inglés
    This book contains six chapters, each of which is a self-contained, thorough review by an expert in the field of a particular topic in medicinal chemistry, bacteriology or pharmacology. Each topic is a currently active subject of research in either the quest for new drugs or a better understanding of the role of known biochemical phenomena. In addition, all of the chapters contain an extensive list of relevant reference books, papers and other publications. The book will be of great interest to medicinal and pharmaceutical chemists, and will serve as a valuable source of reference.

  • Sigma Receptors

    • 1 Edición
    • Volumen 12
    • Inglés
    This is the 12th in the Neuroscience Perspectives Series. The existence of sigma receptors in the central nervous system has only relatively recently been established. In line with the aims of Neuroscience Perspectives, this volume will cover the historical background of the subject, together with the physiological, molecular biological and pharmacological aspects, with a discussion on the concept of sigma receptors subtypes and their postulated relevance for CNS disorders.

  • Immunopharmacology of Joints and Connective Tissues

    • 1 Edición
    • Inglés
    The consequences for diseases involving the immune system such as AIDS, and chronic inflammatory diseases such as bronchial asthma, rheumatoid athritis, and atherosclerosis, now account for a considerable economic burden to governments worldwide. In response there has been an enormous research effort investigating the basic mechanisms underlying such diseases, and a tremendous drive to identify novel therapeutic applications for their preventions and treatment. Though a plethora of immunological studies have been published in recent years, little has been written about the implications of such research for drug development. As a consequence, this area has not gained the prominence of other new fields such as molecular pharmacology or neuropharmacology, and a focal information source for many pharmacologists interested in diseases of the immune system remains unpublished. The Handbook of Immunopharmacology series provides such a source through the commissioning of a comprehensive collection of volumes on all aspects immunopharmacology. Editors have been sought after for each volume who are not only active in their respective areas of expertise, but who also have distinctly pharmacological bias to their research. The series follows three main themes, each represented by volumes on individual component topics. The first covers each of the major cell types and classes of inflammatory responses that can affect them ("Systems"). The third covers different classes of diseases as well as those under development ("Drugs").

  • Immunopharmacology of the Heart

    • 1 Edición
    • Inglés
    This volume sets out to consider a range of cardiac diseases for which drugs may play a therapeutic role by virtue of their effects on aspects of the immune system. The book reviews diseases of the heart which may involve an immunopharmacologica... component, and methods and techniques for the study of physiological and biochemical functions in the heart. An important focus is the immunopharmacology of the coronary vascular endothelium and the role of cellular and biochemical components of the immune system in the pathogenesis of atherosclerosis. The content also includes a review of the use of immunologically relevant agents in the setting of cardiac transplantation from aclinical perspective. Immunotherapy has a definite role to play in cardiology to a greater or lesser extent than other forms of intervention, depending on the type of cardiac disease. Immunopharmacology of the Heart aims to identify and clarify this role and points to potential developments of the future. Immunopharmacology of the Heart is a volume for the SYSTEMS theme of The Handbook of Pharmacology. In common with all other volumes it contains standardized illustrations and terms/abbreviations (glossaries of illustrations and terms published at the back of the volume). Other topics covered include: Leukocytes and their role in ischaemic heart disease. Complement activation. Sudden cardiac death. The stunned myocardium and reperfusion injury.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 46
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 28
    • Inglés

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 30
    • Inglés
    In this volume, the medicinal chemistry of the rapidly expanding family of retinoids, of promising semi-synthetic erythromycins and of the multifaceted amidines is reviewed. Another chapter continues the coverage of inorganic elements which have a medical role; recent studies on the various biological roles of manganese are also examined. Inhibition of enkephalin-degrading enzymes is reviewed, as are studies of the digitalis recognition site which are expected to lead to the development of more highly selective inotropic drugs. This work should be of value to medicinal chemists, pharmacists and pharmacologists. It should also be appreciated by all newcomers, as well as those who wish to be kept up to date with recent work on these topics.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 45
    • Inglés

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 44
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 27
    • Inglés

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 42
    • Inglés

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 33
    • Inglés
    Published since 1959, this serial presents in-depth reviews of key topics in neuroscience, from molecules to behavior. The serial stays keenly atuned to recent developments through the contributions of first-class experts in the many fields of neuroscience. Neuroscientists as well as clinicians, psychologists, physiologists and pharmacoloists will find this serial an indispensable addition to their library.

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 29
    • Inglés
    The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed discussions of some of the most exciting developments in the field today, will prove of great value to future research. The book begins with a study of anti-inflammatory activities of 5-lipoxygenase inhibitors, followed by an overview of the antiarrhythmic therapeutic possibilities offered by Class III electrophysiological agents. Structures and activities of some opioid ligands are surveyed, and the investigation into pharmacologically active pyridazine derivatives is continued. Dopamine D2 receptor agonists offer exciting therapeutic potential, as do ondansetron and related 5-HT 3 antagonists. The herbal origin of many modern drugs is yet again reflected in a survey of the herb feverfew. The volume concludes, as it began, with enzyme inhibition - in this case concerning synthetic inhibitors of interstitial collagenases.

  • Advances in Pharmacology

    • 1 Edición
    • Volumen 23
    • Inglés

  • Analytical Profiles of Drug Substances and Excipients

    • 1 Edición
    • Volumen 20
    • Inglés
    Although the official compendia define a drug substance as to identity, purity, strength, and quality, they normally do not provide other physical or chemical data, nor do they list methods of synthesis or pathways of physical or biological degradation and metabolism. Such information is scattered throughout the scientific literature and the files of pharmaceutical laboratories. Analytical Profiles of Drug Substances brings this information together into one source.

  • Advances in Pharmacology

    • 1 Edición
    • Volumen 22
    • Inglés

  • Drug Resistance As a Biochemical Target in Cancer Chemotherapy

    • 1 Edición
    • Makoto Ogawa
    • Inglés
    Drug Resistance as a Biochemical Target in Cancer Chemotherapy covers the proceedings of the 13th Bristol-Myers Squibb Symposium on Cancer Research, entitled ""Drug Resistance as a Biochemical Target in Cancer Chemotherapy"", hosted by the Japanese Foundation for Cancer Research in Tokyo. This book is divided into four parts encompassing 18 chapters that summarize the results of both preclinical and clinical research on circumvention of drug resistance. The first two parts discuss the genetic aspects of multidrug resistance and the proteins involved in drug resistance. These parts also examine the structure, function, and expression of P-glycoproteins, with an emphasis on the role of these proteins as targets for cancer chemotherapy. The third part describes the methods for detection of P-glycoprotein and its antagonists to counter clinical drug resistance. This topic is followed by a discussion on the interactions among steroid hormones, steroid hormone receptors, antiandrogens, biological-response modifiers, and cytotoxic drugs in human breast cancer. The concluding part explores the clinical applications of chemosensitizers in cancer therapy. This part also considers the alternative clinical approaches against drug failure, including non-crosss-resistant therapies, autologous bone marrow transplantation, dose-intensive therapy, and high-dose chemotherapy. Biomedical scientists and researchers and clinicians will find this book invaluable.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 41
    • Inglés

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 40
    • Inglés

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 28
    • Inglés
    The six reviews in this volume cover once again a most comprehensive range of topics. The anti-malarial activity of the 8-aminoquinolines is examined, with an eye to the development of a single, broad-spectrum drug. Chelation, important in removal of toxic metals from the body, is reviewed for tripositive elements. A new and promising approach to total parenteral nutrition is described. Our indebtedness to the plant origins of many modern drugs is noted in the context of new chemicals. Heterosteroids and receptor-specific opioid peptides constitute two further topics, each case highlighting the wide range of relevant biologically active compounds. Yet another volume challenging the staggering diversity of the field of medicinal chemistry.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 39
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 25
    • Inglés

  • Advances in Pharmacology

    • 1 Edición
    • Volumen 21
    • Inglés

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 38
    • Inglés

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 27
    • Inglés
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 37
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 24
    • Inglés

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 36
    • Inglés

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 35
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 23
    • Inglés

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 25
    • Inglés
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 34
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 22
    • Inglés

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 33
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 21
    • Inglés

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 23
    • Inglés
    There are five main subject areas in this volume in the series on medicinal chemistry. The first is a review of the understanding of Alzheimer's disease and the development of drugs for its treatment; the second, looking at recent efforts in modifying a naturally occuring anticancer (campothecin) for chemotherapy; the third covers the problem of getting a drug to a specific site within the context of phosphates and phosphonates; a survey of sterilization using aldehydes for the destruction of microbes both inside and outside the human body is reviewed in the fourth; and the last chapter is an account of the progress made in the biologically active enantiomer for complex synthetic asymmetric drug molecules.

  • Progress in Nucleic Acid Research and Molecular Biology

    • 1 Edición
    • Volumen 32
    • Inglés

  • Annual Reports in Medicinal Chemistry

    • 1 Edición
    • Volumen 20
    • Inglés

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 22
    • Inglés

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