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Elsevier

Libros en Ciencias de la Vida

  • Self-Learning AI in Healthcare

    Agentic Systems for Smarter Medicine
    • 1 Edición
    • Rajesh Kumar Dhanaraj + 4 más
    • Inglés
    Self-Learning AI in Healthcare: Agentic Systems for Smarter Medicine covers the transformative potential of advanced artificial intelligence within modern medicine. The book addresses the critical need for self-learning and agentic AI systems that autonomously adapt, refine decision-making, and navigate complex clinical environments with minimal intervention. Chapters provide foundational insights into the rise of self-learning AI and neural networks tailored for adaptive medical systems. Subsequent chapters delve into unsupervised, semi-supervised, and reinforcement learning for autonomous healthcare decision-making, alongside decentralized edge AI approaches. Specialized sections cover personalized medicine, hospital workflow optimization, remote patient monitoring, early disease detection, federated learning for privacy preservation, and more.Further, this book explores AI applications in drug discovery, mental health support, radiology, digital twins, and medical robotics, culminating with an examination of future challenges, ethics, and regulatory frameworks shaping self-learning AI’s trajectory in healthcare. It is tailored to serve a diverse yet specialized audience spanning academic, professional, and research sectors. Healthcare IT professionals and clinical informatics specialists will gain practical guidance for implementing adaptive AI solutions within complex healthcare environments. AI researchers and data scientists focused on developing self-learning models will find cutting-edge methodologies and case studies that advance medical applications.

  • SGLT2 Inhibitors in Cardiovascular Diseases

    Mechanisms, Clinical Impact, and Future Directions
    • 1 Edición
    • Tong Liu
    • Inglés
    SGLT2 Inhibitors in Cardiovascular Diseases: Mechanisms, Clinical Impact, and Future Directions reviews the impact of SGLT2 inhibitors on cardiovascular health in individuals with type 2 diabetes, chronic kidney disease, heart failure, and atherosclerosis. The book synthesizes preclinical and clinical evidence to highlight the cardiovascular benefits of these drugs, initially developed for hyperglycemia management. It details recent studies on SGLT2 inhibitors' effects on cognitive dysfunction, sudden death, ventricular arrhythmias, heart remodeling, and cancer risks in diabetic patients.In addition, it compares SGLT2 inhibitors with DPP4 inhibitors, emphasizing the efficacy of empagliflozin and dapagliflozin in reducing syncope and cardiovascular mortality, supported by trials like EMPA-REG OUTCOME and DECLARE-TIMI 58. Addressing a gap in literature, the book provides a comprehensive overview of SGLT2 inhibitors' cardiovascular benefits in high-risk populations, including atrial fibrillation and syncope. It offers valuable insights and recommendations for clinicians, researchers, and policymakers managing cardiovascular risk.

  • RNA-Binding Proteins Part B

    • 1 Edición
    • Volumen 744
    • Inglés
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Rare and Complex Liver Diseases

    • 1 Edición
    • Ansgar Wilhelm Lohse + 2 más
    • Inglés
    Rare and Complex Liver Diseases is a comprehensive guide that fills a critical gap in the literature, providing up-to-date, practical advice. The book is organized into distinct sections, each dedicated to a specific category of liver diseases. Topics covered include Autoimmune Liver Diseases such as Autoimmune Hepatitis (AIH) and Primary Biliary Cholangitis (PBC); Cholestatic Liver Diseases including Biliary Atresia and Alagille Syndrome; Vascular Liver Diseases like Budd-Chiari Syndrome and Non-cirrhotic Portal Hypertension; Metabolic Liver Diseases such as Wilson Disease and Alpha-1 Antitrypsin Deficiency; Structural Liver Diseases including Polycystic Liver Disease; and Rare Liver Tumors like Cholangiocarcinoma and Hemangioendothelioma... chapters cover Liver Disease in Pregnancy and delve into Quality of Life issues, offering evidence-based insights and practical strategies for improving patient well-being. This book serves as an indispensable resource for gastroenterologists, hepatologists, internists, and researchers specializing in liver diseases. It equips these professionals with the knowledge and practical advice necessary to improve patient outcomes and advance their field of study.

  • Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease

    • 1 Edición
    • Dibyajyoti Banerjee
    • Inglés
    Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphasizing the critical need for early detection methods prior to the onset of microalbuminuria. The book's primary focus is on the study of pseudoesterase activity in urinary albumin and other proteins as a potential biomarker for early diagnosis of diabetic kidney disease. This resource bridges a significant gap in current literature by providing an in-depth analysis of how this enzymatic activity can inform the classification and management of diabetic nephropathy.Chapters cover foundational knowledge of diabetes and its complications, the mechanisms of diabetic nephropathy, and detailed discussions on human serum albumin and its enzymatic activities. Each chapter covers the biochemical characterization of pseudoesterase activity, methods for its detection, and the significance of urinary proteomic profiling. Final chapters highlight future research opportunities and the potential for developing point-of-care testing tools, positioning this work as a critical resource for advancing the field of diabetic kidney disease research and clinical practice.

  • Chronic Kidney Disease Management Through Herbal Phytoceuticals

    Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management
    • 1 Edición
    • Kalicharan Sharma
    • Inglés
    Chronic Kidney Disease Management Through Herbal Phytoceuticals: Mechanistic Findings and Phyto-Based Therapy for Chronic Kidney Disease Management examines chronic kidney disease (CKD) through the lens of plant-, marine-, and microbe-derived compounds. The field increasingly requires safer, non-invasive therapies that complement existing regimens while clarifying mechanisms of action. By combining ethnobotanical knowledge with contemporary computational methods, this work serves as a translational resource for researchers, clinicians, and students seeking evidence-based, mechanism-driven phytopharmaceutical approaches to nephroprotection and disease modification. Readers gain a framework for integrating traditional knowledge with modern drug discovery pipelines. The table of contents outlines a progression from foundational concepts to translational applications. Chapters 1–3 cover the global burden, pathophysiology, and current management of CKD. Chapter 4 identifies druggable molecular targets. Chapters 5–7 survey plant-based phytoceuticals for CKD management, marine natural products as emerging CKD therapies, and microbial-derived candidates as potential CKD agents, supported by efficacy and safety data. Chapters 8–9 apply molecular docking and docking-based mechanistic insights to plant, marine, and microbial compounds. Chapters 10–12 address clinically validated phytopharmaceuticals... formulation science, and global regulatory considerations. Chapter 13 presents clinical and preclinical case studies to illustrate practical applications. This book delivers clear benefits to end users by providing integrated, mechanism-driven insights that connect basic science to clinical decision-making. Readers gain access to curated data on plant-, marine-, and microbial-derived compounds along with their targets, efficacy, and safety, supported by docking-based mechanistic validation. It also addresses formulation challenges, regulatory pathways, and quality-control considerations essential for translating phytopharmaceuticals from bench to bedside, including safety assessment and scalable product development. This blend of theory and practical guidance supports researchers designing studies, clinicians implementing evidence-based phytotherapy, and educators teaching multidisciplinary approaches to CKD management across academic and clinical settings.

  • Artificial Intelligence in Immunoengineering

    Methods, Models, and Translational Applications
    • 1 Edición
    • Steven Zanganeh + 1 más
    • Inglés
    Artificial Intelligence in Immunoengineering: Methods, Models, and Translational Applications examines how AI reshapes immunoengineering to design immune-modulating biomaterials, imaging systems, and diagnostic tools. The book presents an integrated view of data-driven approaches that accelerate discovery and translation in biomedicine. It surveys biological data from single-cell to spatial omics and proteogenomics and offers practical machine learning frameworks, generative and mechanistic models, and multimodal integration strategies. Sections address bench-to-bedside translation, validation pipelines, and regulatory considerations for AI-enabled immunoengineering tools.The book highlights the rapid progress of multidisciplinary research within immunotherapy and immunoengineering. Looking forward, the prospects of immunoengineering appear promising, with further advancements in disease prevention, diagnostics, and treatment on the horizon. Graduate students, academic researchers, clinician-scientists... and computational biologists will gain standardized workflows, mechanism-aware modeling, and reproducible pipelines that advance immunotherapies and diagnostics from concept to clinical impact.

  • Evidence Based Diagnosis and Management of Testicular Tumors

    • 1 Edición
    • Axel Heidenreich
    • Inglés
    Evidence Based Diagnosis and Management of Testicular Tumors is a comprehensive reference that addresses the current needs of urologists, oncologists, and related specialists involved in testicular cancer care. This book synthesizes the latest research, clinical guidelines, and expert insights to facilitate accurate diagnosis, staging, and personalized treatment strategies. It emphasizes a multidisciplinary approach, integrating pathology, molecular genetics, imaging, and surgical techniques, to optimize patient outcomes and minimize long-term toxicity. The contents are organized into key sections covering epidemiology, pathology, staging, diagnostic evaluation, disease management, and follow-up. Each chapter begins with case scenarios and interactive questions, fostering active learning and decision-making skills. The book also dedicates sections to rare tumors and pediatric cases, ensuring broad applicability across age groups and tumor types. Visual content, including figures, flow charts, tables, and videos, enhances comprehension and procedural training. This reference aims to bridge the knowledge gap in current testicular cancer management, providing practitioners with practical, guideline-conforming advice. It supports clinicians in delivering individualized, risk-adapted care, ultimately improving survival rates and quality of life for patients. By combining expert perspectives with evidence-based protocols, this book serves as an essential resource for advancing clinical practice in testicular oncology.

  • Autophagy – Part D

    • 1 Edición
    • Volumen 407
    • Inglés
    Autophagy – Part D presents current methods and advances in the study of autophagy, covering experimental approaches, molecular mechanisms, and emerging applications across different biological and disease contexts. It serves as a useful resource for researchers investigating autophagy in cell biology, physiology, and translational research.

  • Neurochemical Substrates of Addiction Medicine

    • 1 Edición
    • Mohammad Banazadeh + 2 más
    • Inglés
    Neurochemical Substrates of Addiction Medicine offers an in-depth exploration of the complex interplay between neurochemistry and addiction, providing critical insights for researchers, clinicians, and students alike. This book is structured into four comprehensive sections, beginning with an examination of the distribution of neurotransmitters across key brain circuitry involved in addiction, such as the mesolimbic, striatal, frontal, insular, and thalamic systems. Each chapter meticulously describes how these circuits contribute to addictive behaviors and the underlying neurobiological mechanisms. The second section delves into the major neurotransmitter systems—including dopaminergic, glutamatergic, GABAergic, adrenergic, serotonergic, cholinergic, endogenous opioid, and purinergic systems—highlighting their roles in addiction.Following this, the book addresses the neuropharmacology of various drugs of abuse, including nicotine, opioids, alcohol, psychomotor stimulants, cannabinoids, psychedelics, sedative-hypnotics, caffeine, and antihistamines, detailing how these substances alter neurochemical pathways. The final section expands the discussion to behavioral addictions, exploring the neurochemical substrates associated with disorders such as pathological gambling, internet use, sexual addiction, and binge eating.

  • The Neurobiological Underpinnings of Addiction Medicine

    Focusing on Novel Approaches
    • 1 Edición
    • Mohammad Shabani + 3 más
    • Inglés
    The Neurobiological Underpinnings of Addiction Medicine: Focusing on Novel Approaches provides a comprehensive review of the biological mechanisms that drive addiction and innovative strategies for treatment. This book begins by examining the crucial role of the microbiome and the gut-brain axis in various substance use disorders, including opioid, alcohol, neurostimulant, and cannabis use disorders. It highlights how gut health can significantly influence addiction behaviors and treatment outcomes. Following this, the second section discusses the interplay between addiction and neuropsychiatric disorders such as depression, anxiety, schizophrenia, ADHD, bipolar disorder, PTSD, and OCD.This section emphasizes the impact of neurotransmitter systems and intracellular pathways on the development and persistence of these disorders. The final section introduces cutting-edge methodologies reshaping addiction research, including multi-OMICS approaches and the implications of CRISPR-Cas9 technology. By integrating these diverse topics, this book offers vital insights for clinicians and researchers alike.

  • High Amylose Cereals

    Impact of Starch Structure and Processing on Nutrition
    • 1 Edición
    • Nese Sreenivasulu + 2 más
    • Inglés
    High Amylose Cereals: Impact of Starch Structure and Processing on Nutrition provides a complete focused reference on resistant starch, its source and its efficient and effective use as part of a healthy diet. Moving the reader from the plant to the product, it guides the reader to greater understanding of the potential for these grains. High amylose starch provides a meaningful amount of dietary fiber through the delivery of starch resistant to digestion. This characteristic provides a mechanism to increase the global consumption of fiber. As high amylose grains are being developed and commercialized, a reference is needed describing the general background, nutritional benefits, underlying trait development, and product development. The scope of this book includes topics ranging from the genetics required for the plant to develop high amylose starch to the nuances of creating finished food products with high amylose grain ingredients, including post-harvest processing technologies, and potential for delivering health benefits to consumers. Edited and contributed by leading experts, the book will be valuable for those seeking to understand the role high amylose cereals can play in the global food supply.

  • A Comprehensive Guide to Surgical Oncology

    • 1 Edición
    • Aqeel Shakir Mahmood + 2 más
    • Inglés
    A Comprehensive Guide to Surgical Oncology is an authoritative reference that meticulously covers the surgical management of various cancers. Each section delves into the latest surgical techniques, treatment protocols, and post-operative care strategies, supported by up-to-date research and clinical evidence. Enriched with detailed illustrations, case studies, and expert insights, this book is an indispensable resource for professionals and students alike. The primary purpose of this book is to provide a comprehensive, up-to-date resource that addresses the current challenges and advancements in surgical oncology. As cancer treatment evolves rapidly with continuous improvements in surgical techniques and multidisciplinary care, there is a pressing need for a new resource that synthesizes these developments into a coherent guide. This book aims to fill that gap by offering a thorough overview of the latest surgical oncology practices, thereby enhancing the knowledge and skills of its readers. This book solves several key problems for its readers by bridging the gap between rapidly advancing research and clinical practice, ensuring access to the latest information. It consolidates a vast amount of information into one comprehensive volume, saving readers the time and effort of consulting multiple sources. Providing practical guidance on the surgical management of a wide range of cancers, it helps practitioners make informed decisions in clinical settings. For students and trainees, it serves as a valuable educational tool that covers both foundational knowledge and advanced concepts in surgical oncology, offering multidisciplinary insights that foster a better understanding of the collaborative efforts required in cancer treatment.

  • Pectin

    Sources, Technological Properties and Functional Applications
    • 1 Edición
    • F.A. Masoodi + 2 más
    • Inglés
    Pectin: Sources, Technological Properties, and Functional Applications provides a comprehensive overview of pectin, detailing its structure, chemistry, properties, functionality, and diverse applications. The book offers valuable insights into how pectin's intrinsic properties affect its functionality and suitability for various end uses. It also explores the sourcing of pectin from food and agro-industrial sources, with a comparative assessment of conventional and emerging extraction technologies, and emphasis on sustainability through waste valorisation. The book is organized into three sections: Pectin Chemistry and Functionality, Valorisation of Agro-Industrial Waste Streams for Sourcing Pectin, and Functional Applications of Pectin in the Food Industry and Allied Arenas. It serves as a valuable resource for academicians, scientists, researchers, industry professionals, and students in Food Science, Chemistry, Chemical Engineering, Material Science, Pharmaceutical Sciences and related fields. Being particularly relevant to those working with food by-product valorization, hydrocolloids, biopolymers, colloid chemistry, and materials science, the book provides insights into the applications of pectin in food packaging, emulsification, encapsulation, and drug delivery.

  • Remote Sensing and Machine Learning in Conservation

    Applications and Techniques
    • 1 Edición
    • Alireza Sharifi
    • Inglés
    In Remote Sensing and Machine Learning in Conservation: Applications and Techniques, readers will discover how cutting-edge technology is transforming our understanding of the natural world. This book explores how remote sensing and machine learning are being used to monitor wildlife populations, map critical habitats, predict the effects of climate change, and identify poaching hotspots. From the analysis of satellite imagery to the use of drones and artificial intelligence, this book provides a comprehensive overview of the latest tools and techniques available to conservationists. Written by a renowned expert in spatial information research, this book introduces readers to the exciting new possibilities opened by the combination of remote sensing and machine learning. Early chapters provide an overview of both emerging technologies and their integration into habitat mapping, species distribution, environmental monitoring, and climate change adaptation. Central chapters explore real-world applications and case studies for combating poaching, managing urban expansion, controlling invasive species, and more. Final chapters explore the funding and policy landscape and conclude with a reflection on the role of these technologies in transforming conservation practices. By equipping readers with an overview of these technologies, case studies of their real-world applications, and sample code, datasets, and open-source tools, Remote Sensing and Machine Learning in Conservation: Applications and Techniques promotes the innovative use of these technologies to address global environmental challenges. This is an essential resource for conservationists, resource managers, environmental scientists, and academics studying novel technological applications to conservation issues.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 2 Edición
    • Joao L. de Quevedo + 2 más
    • Inglés
    Neurobiology of Depression: Road to Novel Therapeutics, Second Edition provides the latest research advances, including interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the novel optogenetic techniques revolutionizing depression research. This new edition aids advanced students and researchers in their understanding of MDD, presenting chapters that explore groundbreaking topics such as the neurobiology of treatment-resistant depression, the mechanisms that make ketamine a better antidepressant, and the link between depression and Alzheimer's disease. Additionally, it covers the neurobiology of suicide in depression, the impact of psychedelics as therapy, and the unique aspects of bipolar depression.The book also examines computational models in depression, the neurobiology of psychotherapy, and the putative mechanisms of action for vagus nerve stimulation as a therapeutic approach. These additions help provide a broader and more comprehensive understanding of depression and its treatment.

  • Food Bioactives and Their Role in Human Health and Nutrition

    • 1 Edición
    • Sajad Ahmad Wani
    • Inglés
    Food Bioactives and their Role in Human Health and Nutrition, is a comprehensive resource offering an in-depth look at essential bioactive compounds, such as polyphenols, flavonoids, plant sterols, omega-3 fatty acids, and probiotics, highlighting their importance in promoting health and preventing chronic diseases. Readers will gain insights into the chemical structures, sources, and bioavailability of these compounds, along with practical dietary recommendations tailored to address common lifestyle-related health challenges such as obesity, diabetes, and cardiovascular disease. Food Bioactives and their Role in Human Health and Nutrition, also addresses emerging trends and challenges in the field, including personalized nutrition approaches and the integration of functional foods and nutraceuticals. It examines the role of food processing on the stability of bioactives, ensuring that health professionals are equipped with the latest knowledge to optimize nutritional strategies.

  • Cell Death Part G

    • 1 Edición
    • Volumen 214
    • Inglés
    Cell Death Part G presents current methods and advances for studying the mechanisms, regulation, and biological significance of cell death. The volume covers experimental and analytical approaches relevant to apoptosis, necrosis, autophagy, and other cell death pathways in both basic and translational research.

  • Algal Bioprospecting and Bioprocessing

    Current Trends and Future Perspectives
    • 1 Edición
    • Nitin Trivedi + 1 más
    • Inglés
    Algal Bioprospecting and Bioprocessing: Current Trends and Future Perspectives explores the rapidly evolving field of algal biotechnology and emphasizes the increasing importance of marine and freshwater algae as sustainable sources of bioproducts. By highlighting recent advancements and industrial applications, it aims to promote translational research and promote a circular bioeconomy within the blue economy framework. The book covers a wide array of topics, including algal biomass processing, bioactive metabolites, proteins, pigments, and biorefinery strategies. Key chapters look into advanced extraction techniques, genetic engineering, and the development of high-value products such as omega-3 fatty acids, oligosaccharides, and biopolymers. The book also explores the role of algae in sustainable agriculture, aquaculture, biofuel production, and space missions, providing a holistic view of current research and future prospects. Algal Bioprospecting and Bioprocessing: Current Trends and Future Perspectives is primarily for university students, academics, researchers, and professionals interested in applied phycology and marine biotechnology. This book also appeals to aspiring algapreneurs, industry experts, and policymakers. It encourages a scientific approach to harnessing algae’s societal benefits and promotes understanding of innovative technologies transforming micro- and macroalgae into valuable industrial products within a sustainable, circular economy.

  • AI and Precision Oncology

    Innovations in Diagnosis and Drug Development
    • 1 Edición
    • Arun Kumar Singh + 2 más
    • Inglés
    AI and Precision Oncology: Innovations in Diagnosis and Drug Development examines the transformative role of artificial intelligence and machine learning in oncology. The book addresses the urgent need for early cancer diagnosis and effective therapeutic treatments, highlighting how technological advancements enable rapid analysis of large datasets to enhance patient outcomes. The content explores clinical applications of next-generation sequencing (NGS) integrated with AI technologies, covering risk prediction, disease detection, biomarker identification, and therapeutic target discovery. The book emphasizes the importance of bioinformatics tools in analyzing NGS data and showcases AI-powered applications that improve cancer diagnosis and prognostication.For the academic audience, this book provides valuable insights into the latest advancements in AI and precision oncology. It equips researchers and clinicians with knowledge on personalized treatment strategies and recent clinical studies, ultimately enhancing understanding of how AI can revolutionize cancer care and improve patient management.

  • Molecular Mechanisms of Cancer Resistance

    Emerging Technologies and Therapeutic Strategies
    • 1 Edición
    • Ahmet Acar
    • Inglés
    Molecular Mechanisms of Cancer Resistance: Emerging Technologies and Therapeutic Strategies explores innovative tools and strategies designed to address the critical issue of drug resistance in cancer treatment. This comprehensive volume is tailored for researchers, clinicians, and students, offering insights into the latest advancements and methodologies in the field. The book covers essential topics such as molecular mechanisms of drug resistance, the tumor microenvironment, and emerging technologies like single-cell analysis and computational modeling. Each chapter features contributions from leading experts, providing a multi-dimensional perspective on both foundational concepts and cutting-edge research.By engaging with this book, the academic audience gains access to groundbreaking research and therapeutic strategies that enhance understanding and practice. The knowledge acquired will inspire collaboration and innovation, ultimately contributing to more effective and personalized cancer treatment approaches.

  • Propolis: Science, Innovation, and Healthcare Applications

    • 1 Edición
    • Jairo Kenupp Bastos
    • Inglés
    Propolis from Hive to Health: A Comprehensive Guide is a key reference for understanding the diverse applications of propolis in healthcare and industry. As a natural product derived from bees, propolis has a long history and notable potential in pharmacology and biotechnology. This book serves as a consolidated resource that brings together current knowledge, research, and developments related to propolis, including coverage of three types—Brazilian green propolis (BrGPs), red propolis (RP), and poplar propolis (PP)—making it valuable for both scholars and practitioners. The Table of Contents covers a broad range of topics, including the origin and formation of propolis, its chemical composition, and contemporary analytical methods. It also examines the biological properties of propolis, such as its antimicrobial, antiviral, and neuroprotective effects, along with information on regulatory standards and future research areas. Each chapter is structured to provide a balance of theoretical context and practical insights. Designed for academics, researchers, and industry professionals, the book offers detailed technical information and guidance on quality control and regulatory compliance. By addressing key issues in the commercialization of propolis-based products, this reference supports a deeper understanding and effective utilization of this natural substance.

  • Neuroinflammation and Biomarker Discovery

    From Mechanisms to Clinical Application
    • 1 Edición
    • Arun Kumar Singh + 1 más
    • Inglés
    Neuroinflammation and Biomarker Discovery: From Mechanisms to Clinical Application offers a detailed exploration of the molecular and cellular processes underlying neuroinflammatory conditions. This essential reference addresses the urgent need for advanced biomarkers that can facilitate early diagnosis, monitor disease progression, and guide personalized treatments in neurodegenerative and autoimmune disorders such as Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. The book synthesizes current knowledge on neuroimmune interactions, glial cell activation, blood-brain barrier integrity, and innate immune signaling pathways, providing a comprehensive framework for understanding neuroinflammatory mechanisms. It also covers state-of-the-art platforms for biomarker discovery, including transcriptomics, proteomics, lipidomics, epigenomics, extracellular vesicles, and neuroimaging techniques, emphasizing their translational potential. The inclusion of disease-specific biomarker landscapes enhances its relevance for clinicians and researchers working in diagnostics and drug development. The final sections focus on translational applications, such as clinical trial design, biomarker validation, and the integration of AI-driven multi-omics data for personalized neuroimmunology. This volume is an indispensable resource for neuroscientists, clinicians, graduate students, biotech professionals, and data scientists seeking to advance understanding and innovation in neuroinflammatory research and clinical practice. By bridging basic science and clinical application, it aims to accelerate the development of targeted therapies and diagnostic tools, ultimately improving patient outcomes in neuroinflammatory diseases

  • Basic Neurochemistry

    Principles of Molecular, Cellular, and Medical Neurobiology
    • 9 Edición
    • Scott Brady + 1 más
    • Inglés
    Basic Neurochemistry: Principles of Molecular, Cellular, and Medical Neurobiology, Ninth Edition is a classic advanced neurochemistry and neurobiology textbook that has a renewed focus on clinical applications. The early chapters focus on fundamental membrane chemistry, cellular signaling, and development of the nervous system. Later chapters cover cell injury and inflammation, neurodegenerative diseases, sensory transduction, and neural processing/behavior. By understanding mechanisms at the molecular and systems level, scientists can develop new pharmacotherapies to treat diseases such as Alzheimer's Disease, Parkinson's Disease, Multiple Sclerosis as well as neuropsychiatric diseases (e.g., schizophrenia, depression, pain, addictions).This book provides a foundation of all key principles of neurochemistry and neurobiology--within the context of human diseases--for advanced students and graduate students in neuroscience, biomedical sciences, as well as clinical neuroscientists and neurologists.

  • Omics Approaches in Rhizosphere Microbiology: Part B

    • 1 Edición
    • Volumen 61
    • Inglés
    Omics Approaches in Rhizosphere Microbiology: Part A offers a definitive, systems-level exploration of the complex microenvironment where plant roots and soil microorganisms interact. As global agriculture faces the dual challenges of climate change and food insecurity, understanding the rhizosphere has shifted from traditional culture-dependent isolation to advanced high-throughput molecular auditing. This volume serves as a comprehensive, technically rigorous manual and structural roadmap, bridging foundational rhizosphere biology with the cutting-edge structural analytical tools of modern polyphasic science.

  • Pioneering Precision in Cancer Treatment through 3D Bioprinting

    • 1 Edición
    • Anand Krishnan + 3 más
    • Inglés
    Pioneering Precision in Cancer Treatment through 3D Bioprinting explores the transformative impact of 3D bioprinting on cancer therapy. This groundbreaking book examines innovative techniques revolutionizing cancer care, from creating patient-specific tumor models to accelerating drug discovery and enabling personalized treatments. It offers a comprehensive look at how 3D bioprinting is reshaping oncology. The book details the creation of intricate tumor models that mimic the in vivo environment, enabling precise drug testing and individualized treatment plans. It highlights 3D bioprinting's role in drug screening, tumor modeling, and creating implantable scaffolds for cancer treatment.By manipulating cell arrangements and microenvironments, 3D bioprinting produces accurate cancer models. For the academic audience, this book blends bioengineering, medical insights, and real-world applications. It provides valuable case studies and developments in 3D cancer model creation, enhancing the understanding of oncogenesis, tumor progression, and therapy responses.

  • Artificial Intelligence Based Primary Care

    Artificial Intelligence and Human Cognition in General Practice and Family Medicine
    • 1 Edición
    • Anthony C. Chang + 5 más
    • Inglés
    Artificial Intelligence Based Primary Care: Artificial Intelligence and Human Cognition in General Practice and Family Medicine provides a comprehensive look into the integration of artificial intelligence within primary care. This book aims to bridge the gap between data scientists and primary care clinicians by presenting potential AI applications, implementation challenges, and real-world clinical scenarios in an accessible manner. Comprised of 5 sections and 20 chapters, it offers both theoretical insights and practical guidance for family medicine practitioners.Additi... the book includes a chapter dedicated to a day in the life of a General Practitioner, showcasing the practical impact of AI. It also features an extra compendium listing the Top 100 articles and best books on Artificial Intelligence. This resource is invaluable for academics, researchers, and clinicians eager to expand their knowledge in this emerging field.

  • Fermented Foods for Wellness

    Understanding Processes and Biosensors
    • 1 Edición
    • Muhammad Shahzad Aslam + 2 más
    • Inglés
    Fermented Foods for Wellness: Understanding Processes and Biosensors delves into the beneficial impact of fermented foods on reducing chronic inflammation, which is linked to numerous diseases. The book comprehensively explores how fermented foods like miso, kefir, and turmeric can enhance bioavailability and promote an anti-inflammatory response in the body. By examining the role of inflammation in various health conditions such as Inflammatory Bowel Disease and arthritis, the book provides valuable insights into the relationship between diet and health.The second section, titled The Industrial Fermentation Process, discusses how biosensor technology deciphers complex flavor compounds in fermented foods. It highlights sustainable fermentation practices and their transformative impact on various industries. The book underscores the importance of optimizing bioreactors to create ideal conditions for microbial growth, thus paving the way for future product development. By combining scientific research with practical applications, this book serves as an essential guide for understanding the intersection of nutrition, health, and industrial processes.

  • Microfluidic Platforms for Rapid Antibiotic Susceptibility Testing (AST)

    Accelerating Diagnosis and Optimizing Antimicrobial Therapy
    • 1 Edición
    • Raju Khan + 4 más
    • Inglés
    Microfluidic Platforms for Rapid Antibiotic Susceptibility Testing (AST): Accelerating Diagnosis and Optimizing Antimicrobial Therapy provides a comprehensive and interdisciplinary exploration of microfluidic technologies as transformative tools in the fight against antimicrobial resistance (AMR). By integrating foundational knowledge of AMR and microfluidics with cutting-edge research, it offers readers an in-depth understanding of how microfluidic systems enable rapid, precise, and cost-effective antibiotic susceptibility testing (AST). The book addresses both the scientific principles and practical applications of these technologies, emphasizing their potential to revolutionize diagnostics, personalize treatment, and improve global health outcomes amidst the growing threat of drug-resistant infections. Organized into five key parts, the book begins with an overview of the global challenge of antimicrobial resistance and the fundamental principles of microfluidics in biomedical contexts. It then delves into various microfluidic platforms for AST, including continuous flow and droplet-based systems, as well as single-cell trapping techniques. Subsequent chapters focus on diverse detection methods—optical, electrochemical, and acoustic—for monitoring bacterial growth and antibiotic response. The book further explores specialized approaches such as paper-based point-of-care devices, biosensing strategies, and personalized medicine applications. The final section addresses clinical translation, covering validation, regulatory considerations, device design, automation, emerging technologies, ethical guidelines, and future perspectives on microfluidic AST’s role in combating antimicrobial resistance worldwide.

  • Management of Chronic Kidney Disease and Its Complications

    • 1 Edición
    • Thakur Gurjeet Singh + 4 más
    • Inglés
    Management of Chronic Kidney Disease and Its Complications  presents the latest scientific advances in diagnosing and managing Chronic Kidney Disease (CKD) and its diverse complications. This authoritative text covers molecular mechanisms such as inflammation and oxidative stress, genetic and epigenetic factors, and explores cutting-edge technologies including artificial intelligence and regenerative medicine. With detailed chapters on cardiovascular, metabolic, neurological, and hematological complications, the book offers a holistic approach to understanding CKD’s complexity and evolving treatment strategies.The book’s content is organized to provide a thorough exploration of CKD, beginning with foundational topics like genetic contributions and diagnostic evaluation, progressing through specific complications such as diabetic nephropathy, hypertension, and urologic conditions. Special focus is given to management strategies, nutritional interventions, and unique considerations in pediatric, geriatric, and pregnant populations. Emerging therapies, including precision medicine, gut microbiota modulation, and AI-driven early detection, are also extensively covered to keep readers at the forefront of nephrology research and clinical practice.Management of Chronic Kidney Disease and Its Complications is an essential resource for nephrologists, general practitioners, medical students, nursing professionals, and healthcare providers involved in kidney disease care and research.

  • Applications of Microfluidics Device Technology

    • 1 Edición
    • Volumen 227
    • Inglés
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

  • Federated Quantum Convolutional Neural Networks in Healthcare

    Enhancing Privacy and Efficiency
    • 1 Edición
    • Abhishek Kumar + 3 más
    • Inglés
    Federated Quantum Convolutional Neural Networks in Healthcare: Enhancing Privacy and Efficiency explores the innovative intersection of quantum computing and federated learning in the context of healthcare. As medical data grows exponentially and privacy concerns intensify, this book addresses the urgent need for secure, scalable AI solutions that enable collaborative data analysis without compromising patient confidentiality. It offers a detailed examination of the theoretical foundations of quantum machine learning and federated systems, complemented by practical case studies spanning medical imaging, genomics, and disease diagnosis. The content delves into architecture design, security protocols, and optimization techniques, equipping researchers and practitioners with the tools to develop privacy-preserving AI models tailored for medical applications. The book also discusses regulatory considerations, deployment challenges, and future research directions, positioning itself as a vital resource for advancing healthcare AI. Its comprehensive approach bridges fundamental science and real-world implementation, empowering healthcare professionals, data scientists, and policy makers to harness next-generation quantum federated systems for improved patient outcomes and data security. This resource is essential for those seeking to implement cutting-edge AI technologies in healthcare, ensuring secure, efficient, and collaborative medical data analysis.

  • Introduction to Bioinformatics and Machine Learning

    • 1 Edición
    • Milana Frenkel-Morgenstern
    • Inglés
    Introduction to Bioinformatics and Machine Learning provides comprehensive instruction in modern computational biology by integrating bioinformatics, genomics, artificial intelligence, and machine learning into a unified learning framework. The book bridges the gap between biological data analysis and computational methods, covering fundamental concepts in molecular biology and bioinformatics together with practical applications of machine learning to genomics, transcriptomics, proteomics, microbiome research, structural biology, NGS technologies, liquid biopsy, cancer genomics, and precision medicine. Readers are introduced to DNA and RNA sequencing technologies, genome assembly, sequence alignment, variant discovery, gene expression analysis, fusion gene detection, protein structure prediction, biological databases, statistical analysis, explainable artificial intelligence, and predictive modeling. Throughout the book, real-world biomedical case studies demonstrate how computational methods are transforming modern biological and clinical research; and both bioinformatics and machine learning are addressed in a coherent and accessible manner, emphasizing practical problem-solving, reproducible computational workflows, and biological interpretation of results.Designed for upper-level undergraduate students, graduate students, and researchers, this book serves as both a classroom textbook and practical assignments for those working at the interface of biology, computer science, medicine, and data science.

  • Hypoxia-induced Tumor Heterogeneity and Immune Evasion

    Clinical Interventions
    • 1 Edición
    • Benjamin Bonavida + 1 más
    • Inglés
    Hypoxia-induced Tumor Heterogeneity and Immune Evasion: Clinical Interventions explores how hypoxic stress within the tumor microenvironment drives cancer progression, immune escape, and resistance to therapy. The volume integrates foundational and cutting-edge insights into tumor biology, immunology, and therapeutic innovation. It is structured into five parts, covering tumor heterogeneity, hypoxia-driven mechanisms, immune evasion, clinical diagnostics, and future directions. Topics include metabolic reprogramming, angiogenesis, immune suppression, and hypoxia-targeted therapies, with emphasis on translational relevance.By bringing together global experts to examine how hypoxia shapes tumor evolution, alters immune responses, and influences treatment outcomes, this resource benefits researchers, clinicians, and advanced students by offering a comprehensive, up-to-date synthesis of a rapidly evolving field. It supports deeper understanding of tumor complexity and equips readers with knowledge to inform experimental design, clinical strategies, and therapeutic development in oncology.

  • Plant Development

    • 1 Edición
    • Volumen 172
    • Inglés
    Plant Development provides an overview of the fundamental processes that govern the growth, differentiation, and organization of plants throughout their life cycle. The book explores key developmental stages, from embryogenesis and seed germination to organ formation, flowering, and senescence, highlighting the genetic, molecular, cellular, and environmental factors that regulate these events. By integrating classical concepts with modern advances in developmental biology, the volume offers valuable insight into how plants establish form, adapt to their surroundings, and coordinate growth in response to internal and external signals. It serves as a useful resource for researchers, students, and professionals interested in plant biology, developmental mechanisms, and related fields.

  • Federated Intelligence in Medicine

    AI-Driven Robotics for Secure and Intelligent Healthcare Systems
    • 1 Edición
    • Manisha Guduri + 3 más
    • Inglés
    Federated Intelligence in Medicine: AI-Driven Robotics for Secure and Intelligent Healthcare Systems explores the rapidly evolving field where medical robotics intersects with cutting-edge artificial intelligence and secure data-sharing technologies. Covering a comprehensive range of topics, the book begins with foundational knowledge in medical robotics and Generative AI, progressing to advanced concepts such as federated learning and architectural modeling tailored for AI-driven robotic systems. Readers will explore algorithms enhancing surgical robotics, remote robotic surgeries, and human-robot interaction. The text also tackles AI-driven diagnostic robots, privacy preservation through homomorphic encryption, and differential privacy and emerging medical imaging techniques integrated with robotics.Later chapters examine the synergy of large language models, agent AI, and edge AI with robotic technologies, providing both theoretical frameworks and practical case studies that illuminate real-world applications and challenges. This book is an invaluable resource for researchers and academicians engaged in artificial intelligence, robotics, and medical technology. It also serves undergraduate and graduate students in Biomedical Engineering, Electronics and Electrical Engineering, and Computer Science and Engineering.

  • Implications of Artificial Intelligence in Next Generation Physiotherapy

    • 1 Edición
    • Manpreet Kaur + 3 más
    • Inglés
    Implications of Artificial Intelligence in Next Generation Physiotherapy explores how artificial intelligence is transforming the future of physiotherapy across the entire continuum of rehabilitation. Covering musculoskeletal, neurological, cardiopulmonary, sports, paediatric, geriatric, women's health, and community-based physiotherapy, the book highlights how AI is reshaping clinical practice through intelligent assessment, precision rehabilitation, personalized treatment planning, predictive analytics, remote monitoring, and data-driven clinical decision-making.The book presents comprehensive coverage of emerging AI technologies, including machine learning, deep learning, computer vision, wearable sensors, robotics, virtual and augmented reality, digital twins, tele-rehabilitation, and intelligent clinical decision support systems. It also discusses workload monitoring, movement analysis, biomechanical assessment, functional outcome prediction, patient engagement, and continuous recovery tracking, supported by current research, real-world applications, and clinical case studies.Designed for researchers, clinicians, educators, students, and healthcare innovators, this book bridges the gap between cutting-edge artificial intelligence and evidence-based physiotherapy practice. By examining both current applications and future directions, it provides readers with the knowledge required to implement AI-driven innovations that enhance diagnostic accuracy, optimize rehabilitation outcomes, improve healthcare accessibility, and advance patient-centred care in the next generation of physiotherapy.

  • Endoscopic/Robotic Thyroidectomy Surgery

    Using the Gasless Unilateral Axillary Approach
    • 1 Edición
    • Chuanming Zheng + 1 más
    • Inglés
    Endoscopic/Robotic Thyroidectomy Surgery: Using the Gasless Unilateral Axillary Approach is a comprehensive and systematic resource on endoscopic/robotic thyroidectomy using the gasless unilateral axillary approach comprehensive and systematically presented resource on the gasless axillary approach to endoscopic/robotic thyroidectomy. It includes a detailed introduction to all aspects of surgical treatment including anesthesia coordination and robotic surgery. The book provides practical guidance on postoperative complication management and postoperative care and describes specific methods for technical simulation training and functional exercises. While many journal papers on specific aspects of this surgical approach have been published, no book is currently available.

  • The Fundamentals of Customer-Centered Design of Food Products

    A Multisensory Strategy Integrating Emerging Techniques
    • 1 Edición
    • Luis H. Reyes + 3 más
    • Inglés
    The Fundamentals of Customer-Centered Design of Food Products: A Multisensory Strategy for Integrating Emerging Techniques, is a comprehensive guide for students, and food industry professionals, dedicated to creating food and beverage products that truly resonate with today's consumers. This fundamental resource bridges the gap between traditional product-centric development and modern, holistic approaches that focus on the complete sensory and consumer experience. Divided into three sections, the book begins with laying the foundations for understanding customer-centered food product design and understanding the consumer in multisensory food experiences. Section two explores how each sensory modality interacts to influence consumer perception and satisfaction to create products with optimized nutrition and personalized consumer appeal. The book concludes with section three highlighting the technology and innovative tools such as smart sensors, digital tools, and sustainable processes, used to achieve consumer-centered food product design. The authors also discuss how to communicate sensory value in marketing and brand strategies and future perspectives in consumer-centered multi-sensory food design.

  • Novel Technologies for the Processing and Preservation of Muscle Foods

    • 1 Edición
    • Alaa El-Din A. (Aladin) Bekhit + 1 más
    • Inglés
    Novel Technologies for Processing and Preservation of Muscle Foods explores emerging and innovative technologies in the food industry and their role in enhancing the quality, safety, and sustainability of meat, fish, and seafood. Each chapter explores the biochemistry and microbiology underlying these technologies, their applications in the food industry, and the challenges and successes encountered in commercial settings. From improving tenderness and digestibility to developing hypoallergenic and functional foods, the book highlights the transformative potential of cutting-edge methods to meet the evolving demands of consumers and the food industry. Structured to provide a thorough understanding of both theory and practical applications, this book covers a wide range of topics, including the use of robotics and automation in meat processing, the development of biodegradable packaging, and the implications of Industry 4.0 technologies in food production. With contributions from leading experts, Novel Technologies for Processing and Preservation of Muscle Foods not only addresses existing gaps in knowledge but also proposes future directions for research and innovation. This timely resource will serve as a key reference for researchers, students, and professionals interested in the latest advancements in the processing and preservation of meat, fish, and seafood.

  • Olive 4.0

    Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production
    • 1 Edición
    • Najla Trabelsi + 1 más
    • Inglés
    Olive 4.0: Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production explores the revolutionary impact of Industry 4.0 technologies on the traditional olive sector. As olive farming and oil production face increasing pressures from labor shortages, resource constraints, and environmental concerns, this book addresses the urgent need for digital innovation tailored specifically to this industry. By focusing on cutting-edge tools such as the Internet of Things (IoT), Artificial Intelligence (AI), robotics, blockchain, and smart sensors, it highlights how these advances can enhance sustainability, productivity, and quality throughout the entire olive supply chain—from grove management to oil processing and distribution.Whether for smallholders seeking affordable solutions or large producers aiming for automation and traceability, the book delivers science-backed insights that promote eco-friendly practices while improving efficiency and reducing waste. Importantly, it also addresses challenges related to technology accessibility and equitable adoption, ensuring that innovations benefit a broad spectrum of stakeholders and support long-term sustainability goals.

  • Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science

    • 1 Edición
    • Rahul Mehra + 4 más
    • Inglés
    Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science is a critical resource for researchers, industry professionals, and academics seeking to stay at the forefront of the evolving food landscape. This comprehensive volume is organized into six sections, beginning with foundational principles in food, nutrition, and culinary science—covering chapters such as Interconnection Between Food, Nutrition, and Culinary Science and Fundamentals of Food Science and Technology. It then progresses by exploring cutting-edge innovations in culinary science, including Molecular Gastronomy and Neuro-Gastronomy, alongside practical insights into food processing advancements like AI and Robotics. The book dedicates significant focus to nutrition and health, highlighting breakthroughs in personalized nutrition, nutrigenomics, and functional foods. The final sections address sustainability, ethical practices, and future horizons, including discussions on food waste reduction, sustainable food systems, and future foods. Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science is vital for leveraging scientific and technological progress to develop healthier, safer and more sustainable food solutions. By integrating insights from culinary arts, food processing, and nutritional science, it equips professionals with the knowledge to innovate responsibly and address global issues such as food security, safety, and environmental impact. Whether exploring the role of emerging ingredients or the future of personalized diets, this book offers a detailed roadmap to shape the future of food in both academia and industry.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1 Edición
    • Justin Belcher
    • Inglés
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

  • Artificial Intelligence in Point-of-Care Nanobiosensors Technology

    Enhancing Disease Diagnostics and Improved Healthcare Outcomes
    • 1 Edición
    • Tharmaraj Vairaperumal + 2 más
    • Inglés
    Artificial Intelligence in Point-of-Care Nanobiosensors Technology: Enhancing Disease Diagnostics and Improved Healthcare Outcomes delves into the revolutionary integration of artificial intelligence (AI) with nanobiosensors to elevate point-of-care (POC) diagnostics for both communicable and non-communicable diseases. Readers will find insightful chapters covering topics ranging from foundational AI and machine learning techniques to specific applications in cardiovascular disease, diabetes, cancer, chronic respiratory ailments, and infectious diseases. Each chapter not only highlights recent breakthroughs in nanobiosensors but also emphasizes the pivotal role of AI in enhancing diagnostic accuracy and facilitating personalized health interventions. Additional discussions around regulatory considerations and the future landscape of AI in biomedical research make this an essential read for those navigating this rapidly evolving field. This book primarily targets researchers and professionals engaged in the interdisciplinary realms of AI, nanomaterials, and biomedical sciences. By providing a critical understanding of emerging AI-based diagnostic technologies and their applications in POC settings, this book fosters collaboration across diverse scientific domains.

  • 3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology

    Innovations for Personalized Oncology
    • 1 Edición
    • Ashok Kumar + 2 más
    • Inglés
    3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology: Innovations for Personalized Oncology presents a comprehensive exploration of the transformative role of 3-D bioprinting and bio-generative engineering in modern medicine, with a specific focus on precision oncology. By examining innovative applications of these technologies, the book aims to bridge the gap between emerging scientific advancements and their practical implications in clinical settings. It delves into how patient-specific models of human tissues and organs can revolutionize drug testing, disease diagnostics, and personalized treatment plans, ultimately enhancing the quality of cancer care.Addressing critical challenges in oncology, this book highlights how 3-D bioprinting and bio-generative engineering can improve the accuracy of drug efficacy evaluations, reduce reliance on animal testing, and tackle the pressing issue of organ shortages for transplantation. Furthermore, it emphasizes the ethical considerations and regulatory challenges associated with integrating these technologies into everyday oncology practice, ensuring a balanced perspective on their adoption.

  • Pheochromocytoma, Paraganglioma and Adrenocortical Carcinoma: Physiopathology and Diagnosis

    • 1 Edición
    • Volumen 133
    • Inglés
    Volume 133 provides a comprehensive and up-to-date overview of three of the most challenging endocrine neoplasms—pheochromo... paraganglioma, and adrenocortical carcinoma. Bringing together contributions from internationally recognized experts, this volume explores the latest advances in tumor biology, genetics, molecular mechanisms, and endocrine pathophysiology, while offering a practical approach to modern diagnostic strategies. Readers will find detailed discussions on hereditary syndromes, genotype–phenotype correlations, biochemical testing, imaging modalities, histopathological assessment, molecular profiling, and emerging biomarkers that are reshaping the diagnosis and risk stratification of adrenal tumors. Integrating cutting-edge scientific discoveries with clinical practice, this volume serves as an essential resource for endocrinologists, oncologists, endocrine surgeons, pathologists, radiologists, nuclear medicine specialists, geneticists, researchers, and trainees seeking to improve the diagnosis and understanding of these rare but clinically significant endocrine malignancies. With its multidisciplinary perspective and strong translational focus, Volume 133 is an indispensable reference for clinicians and scientists dedicated to advancing adrenal tumor care and research.

  • The NeuroComplex Interaction of Appetite Regulation

    Brain, Body and Environment
    • 1 Edición
    • Nasrollah Moradikor + 1 más
    • Inglés
    The NeuroComplex Interaction of Appetite Regulation: Brain, Body and Environment presents the latest research on why we eat, what makes us hungry, and how our brain controls our cravings. The book covers the data for how the brain, hormones, and different factors such as stress, the environment, and even food itself affects our desire to eat. Written for academics and researchers, this book helps facilitate a comprehensive understanding on how the brain influences appetite regulation, allowing readers to understand how neurobiological mechanisms can help treat patients involved with obesity, eating disorders, or other related conditions.Readers will find this to be a reliable resource that connects current neuroscience research with practical applications in appetite and behavior.

  • Emerging Technologies in Bioengineering for Oncology

    Fundamentals, Research, and Future Prospects
    • 1 Edición
    • Saikat Das + 2 más
    • Inglés
    Emerging Technologies in Bioengineering for Oncology: Fundamentals, Research, and Future Prospects explores the integration of engineering, biology, and medicine to tackle challenges in developing innovative tools for cancer diagnosis and treatment. This comprehensive resource addresses the evolving landscape of bioengineering in oncology, highlighting the intersection of various disciplines to drive advancements in diagnostic and therapeutic approaches. The book explores a range of cutting-edge technologies such as lab-on-chip devices, wearable biosensors, 3D bioprinting, and targeted nanomedicine, offering promising avenues for enhanced diagnostic precision, treatment effectiveness, and personalized healthcare.Geared towards medical students and professionals, the book provides detailed insights into the latest developments, practical applications, and future research directions in the field. By offering a deep dive into the realm of bioengineering for oncology, it serves as a valuable asset for those seeking to advance cancer care through interdisciplinary collaboration and innovation.

  • Geostatistical Approaches to Environmental and Public Health Issues

    • 1 Edición
    • Deepak Kumar + 4 más
    • Inglés
    Geostatistical Approaches to Environmental and Public Health Issues discusses how geostatistical techniques can be leveraged to better understand and respond to pressing environmental and public health challenges. The book showcases how techniques like kriging, spatial regression, Bayesian modeling, and space-time analysis offer powerful, nuanced insights into these issues. Emphasizing stochastic, non-deterministic approaches, it highlights the importance of modeling uncertainty in both environmental and health domains. Through case studies and research-driven chapters, sections demonstrate how integrating geospatial and statistical methods can enhance our understanding of where, why, and how events occur—ultimately improving the precision of health interventions and environmental policies.By aligning cutting-edge statistical approaches with the geospatial dimensions of health and environmental data, this book fills a critical gap in the literature and supports more targeted, data-driven decision-making in the face of global uncertainty. It bridges methodological innovation with applied research, making it an essential resource for scientists, policymakers, and public health practitioners.

  • Endophyte Technology

    An Integrative Approach for Agriculture, Healthcare, and Environmental Sustainability
    • 1 Edición
    • Zahoor Ahmed Wani + 2 más
    • Inglés
    Endophyte Technology: An Integrative Approach for Agriculture, Healthcare, and Environmental Sustainability explores how understanding endophyte biology can be utilized in agriculture, medicine, and environmental remediation. As the global population continues to grow, the pressures on agricultural systems to produce sufficient food sustainably are intensifying. Concurrently the need for innovative medical solutions and effective environmental conservation practices is becoming increasingly urgent. This book addresses these critical needs by offering a detailed account of endophytes and their potential applications across these important fields.The book is structured into three parts, covering agricultural, ecological, and pharmaceutical aspects of endophytes. Part I looks into the role of endophytes in agriculture, discussing their potential in promoting plant growth, enhancing nutrient acquisition, and providing stress tolerance to plants. It explores how endophytes can promote sustainable agriculture, reducing the reliance on synthetic fertilizers and pesticides. Subsequent chapters explore topics such as endophyte colonization patterns, phytohormone production, and the development of bioformulations like biofertilizers, biopesticides, and biocontrol agents. Part II focuses on the ecological significance of endophytes, examining their role in ecosystem functioning, bioremediation, and adaptation to extreme environments. Part III highlights the pharmaceutical potential of endophytes, centering their ability to produce bioactive metabolites with antimicrobial, anticancer, and anti-inflammatory properties, and their role in drug discovery and biofuel production.This book is an important resource for undergraduate and postgraduate students as well as researchers and professionals in agriculture, horticulture, botany, biochemistry, and biotechnology.

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