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Elsevier

Libros en Ciencias de la Vida

  • Effect of High Temperature on Crop Productivity and Metabolism of Macro Molecules

    • 1 Edición
    • Amitav Bhattacharya
    • Inglés
    Effect of High Temperature on Crop Productivity and Metabolism of Macro Molecules presents a comprehensive overview on the direct effect of temperatures defined as "high", a definition which increasingly includes a great number of geographic regions. As temperature impacts the number of base growth days, it is necessary to adapt plant selection, strategize planting times, and understand the expected impact of adaptive steps to ensure maximum plant health and crop yield. Global warming, climate change and change in environmental conditions have become common phrases in nearly every scientific seminar, symposium and meeting, thus these changes in climatic patterns constrain normal growth and reproduction cycles. This book reviews the effect of high temperature on agricultural crop production and the effect of high temperature stress on the metabolic aspects of macro molecules, including carbohydrates, proteins, fats, secondary metabolites, and plant growth hormones.

  • Numerical PDE Analysis of Retinal Neovascularization

    Mathematical Model Computer Implementation in R
    • 1 Edición
    • William E. Schiesser
    • Inglés
    Numerical PDE Analysis of Retinal Neovascularization Mathematical Model Computer Implementation in R provides a methodology for the analysis of neovascularization (formation of blood capillaries) in the retina. It describes the starting point—a system of three partial differential equations (PDEs)—that define the evolution of (1) capillary tip density, (2) blood capillary density and (3) concentration of vascular endothelial growth factor (VEGF) in the retina as a function of space (distance along the retina), x, and time, t, the three PDE dependent variables for (1), (2) and (3), and designated as u1(x, t), u2(x, t), u3(x, t), amongst other topics.

  • New and Future Developments in Microbial Biotechnology and Bioengineering

    Microbial Secondary Metabolites Biochemistry and Applications
    • 1 Edición
    • Vijai G. Gupta + 1 más
    • Inglés
    New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community.

  • Intrinsically Disordered Proteins

    Dynamics, Binding, and Function
    • 1 Edición
    • Nicola Salvi
    • Inglés
    Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs.

  • Biopolymer Nanostructures for Food Encapsulation Purposes

    Volume 1 in the Nanoencapsulation in the Food Industry series
    • 1 Edición
    • Volumen 1
    • Seid Mahdi Jafari
    • Inglés
    Biopolymer Nanostructures for Food Encapsulation Purposes, a volume in the Nanoencapsulation in the Food Industry series, guides readers on how to fabricate and apply nanostructures from different proteins, carbohydrates and chemical sources for food encapsulation purposes. This book covers recent and applied research in all disciplines of bioactive and nutrient delivery. Chapters emphasize original results relating to experimental, theoretical, formulations and/or applications of nano-structured biopolymers.

  • Mitochondrial Neuropathies

    • 1 Edición
    • Volumen 145
    • Inglés
    Mitochondrial Neuropathies, Volume 146, brings together experts in a range of diseases that damage the nervous system to present the role of mitochondrial dysfunction in their particular field, with this new release focusing on Mitochondrial dysfunction in Alzheimer's Disease, HIV and the mitochondrial: immune interface in the CNS, The Impact of mitochondrial damage in HIV-induced peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of chemotherapy-induced peripheral neuropathy, Disorders of mitochondrial biogenesis in peripheral neuropathy, Mitochondrial dysfunction and the pathogenesis of diabetic neuropathy, Manipulating mitochondria to treat peripheral neuropathy, and DCA therapy - the yin and yang of mitochondrial activation.

  • Equipment Qualification in the Pharmaceutical Industry

    • 1 Edición
    • Steven Ostrove
    • Inglés
    Equipment Qualification in the Pharmaceutical Industry provides guidance and basic information for the preparation of a quality qualification program. It has been noted that there is a general lack of understanding in the industry, especially for those new to the industry, as to what constitutes a compliant qualification program. Even experienced professionals have felt a lack of security in reaching a compliant state. This book outlines a guideline for the preparation and execution of qualification protocols including the installation (IQ), operational (OQ), and performance (PQ) protocols. It discusses the importance of related qualification programs (e.g., quality systems, commissioning, computer system, and cleaning) and how to incorporate them into a fully compliant qualification program. Furthermore, it provides matrices of what could be included in each type of protocol for major types of process equipment. While primarily for people entering the pharmaceutical industry, those established in the field will benefit from the multiple examples and matrices as well as integration of related systems. Equipment Qualification in the Pharmaceutical Industry provides students and pharmaceutical scientists a guideline for the preparation and execution of qualification (installation, operational, and performance) protocols.

  • Dietary Fiber: Properties, Recovery, and Applications

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Dietary Fiber: Properties, Recovery and Applications explores the properties and health effects of dietary fiber, along with new trends in recovery procedures and applications. The book covers the most trending topics of dietary fiber applications, emphasizing polyphenol properties, bioavailability and metabolomics, target sources, recovery and emerging technologies, technological aspects, stability during processing, and applications in the food, beverage and nutraceutical sectors. Written by a team of experts in the field of dietary fiber, this book is ideal for chemists, food scientists, technologists, new product developers and academics.

  • Development of the Nervous System

    • 4 Edición
    • Dan H. Sanes + 3 más
    • Inglés
    Development of the Nervous System, Fourth Edition provides an informative and up-to-date account of our present understanding of the basic principles of neural development as exemplified by key experiments and observations from past and recent times. This book reflects the advances made over the last few years, demonstrating their promise for both therapy and molecular understanding of one of the most complex processes in animal development. This information is critical for neuroscientists, developmental biologists, educators, and students at various stages of their career, providing a clear presentation of the frontiers of this exciting and medically important area of developmental biology. The book includes a basic introduction to the relevant aspects of neural development, covering all the major topics that form the basis of a comprehensive, advanced undergraduate and graduate curriculum, including the patterning and growth of the nervous system, neuronal determination, axonal navigation and targeting, neuron survival and death, synapse formation and plasticity.

  • Immunotherapy of Cancer

    • 1 Edición
    • Volumen 143
    • Inglés
    Immunotherapy of Cancer, Volume 143, the latest release in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. Contributions from leading experts in the field make this a must have update on the topic.

  • Mechanical Behavior of Biomaterials

    • 1 Edición
    • J. Paulo Davim
    • Inglés
    Mechanical Behaviour of Biomaterials focuses on the interface between engineering and medicine, where new insights into engineering aspects will prove to be extremely useful in their relation to the biomedical sciences and their applications. The book's main objective focuses on the mechanical behavior of biomaterials, covering key aspects, such as mechanical properties, characterization and performance. Particular emphasis is given to fatigue, creep and wear, fracture, and stress and strain relationships in biomaterials. Chapters look at both experimental and theoretical results. Readers will find this to be an essential reference for academics, biomechanical researchers, medical doctors, biologists, chemists, physicists, mechanical, biomedical and materials engineers and industrial professionals.

  • The Solar Corridor Crop System

    Implementation and Impacts
    • 1 Edición
    • C. LeRoy Deichman + 1 más
    • Inglés
    The Solar Corridor Crop System: Implementation and Impacts presents a case-study format on the planning and implementation of alternative cropping systems designed to maximize incident sunlight and bio-support of all crops in a rotation system. The book describes the basic component of the system, an increased access point of incident sunlight between each row or pairs of rows that enables a more uniform vertical distribution of incident sunlight to chloroplasts within the entire corn leaf canopy. While the production environment and environment specific genetics determine the performance potential of this principle, by maximizing the principles that light is basic to crop yield, a solar corridor ultimately contributes to increased grain yield. Written by experts who were integral in the development of solar corridor systems, and providing real-world examples of the methods, challenges and future prospects, this book will be valuable for those seeking to increase yield-per-acre through both primary and cover-crops.

  • Rhinovirus Infections

    Rethinking the Impact on Human Health and Disease
    • 1 Edición
    • Nathan Bartlett + 2 más
    • Inglés
    Rhinovirus Infections: Rethinking the Impact on Human Health and Disease provides a timely review of the impact of rhinovirus infections on human health. It identifies disease mechanisms relating to the virus, human host and environmental factors. This viewpoint allows us to look forward to the development of treatments for a virus for which treatment options are currently non-existent. By providing detailed insights into this virus, its host and the environmental factors that play into rhinovirus induced diseases, this book explains disease mechanisms and summarizes existing and developing therapeutic approaches for better research, diagnosis and potential treatments.

  • Synaptic Transmission

    • 1 Edición
    • Stephen D. Meriney + 1 más
    • Inglés
    Synaptic Transmission is a comprehensive guide to the topic of neurotransmission that provides an in-depth discussion on many aspects of synapse structure and function—a fundamental part of the neuroscience discipline. Chapters include boxes that describe renowned/award-winni... researchers and their contributions to the field of synaptic transmission, diseases relevant to the material presented, details of experimental approaches used to study synaptic transmission, and interesting asides that expand on topics covered. This book will inspire students to appreciate how the basic cellular and molecular biology of the synapse can lead to a better understanding of nervous system function and neurological disorders.

  • Omega Fatty Acids in Brain and Neurological Health

    • 2 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases.

  • Biodiversity of Pantepui

    The Pristine "Lost World" of the Neotropical Guiana Highlands
    • 1 Edición
    • Valentí Rull + 3 más
    • Inglés
    Biodiversity of Pantepui: The Pristine "Lost World" of the Neotropical Guiana Highlands provides the most updated and comprehensive knowledge on the biota, origin, and evolution of the Pantepui biogeographical province. It synthesizes historical information and recent discoveries, covering the main biogeographic patterns, evolutionary trends, and conservational efforts. Written by international experts on the biodiversity of this pristine land, this book explores what makes Pantepui a unique natural laboratory to study the origin and evolution of Neotropical biodiversity under the influence of only natural drivers. It discusses the organisms living in Pentepui, including algae, plants, several groups of invertebrates, birds, amphibians, reptiles, and mammals. The latter portion of the book delves into the effects of human activity and global warming on Pantepui, and current conservational efforts to combat these threats. Biodiversity of Pantepui is an important resource for researchers in ecology, biogeography, evolution, and conservation, who want to understand the biodiversity and natural history of this region, and how to help conserve and protect the Guiana Highlands from environmental and human damages.

  • Light and Video Microscopy

    • 3 Edición
    • Randy O. Wayne
    • Inglés
    Light and Video Microscopy, Third Edition provides a step-by-step journey through philosophy, psychology and the geometrical and physical optics involved in interpreting images formed by light microscopes. The book addresses the intricacies necessary to set up light microscopes that allow one to visualize transparent specimens and, in the process, quantitatively determine various physico-chemical properties of specimens. This updated edition includes the most recent developments in microscopy, ensuring that it continues to be the most comprehensive, easy-to-use, and informative guide on light microscopy. With its presentation of geometrical optics, it assists the reader in understanding image formation and light movement within the microscope.

  • Handbook of Nutrition, Diet, and the Eye

    • 2 Edición
    • Victor R. Preedy + 1 más
    • Inglés
    Handbook of Nutrition, Diet, and the Eye, Second Edition, thoroughly addresses common features and etiological factors on how dietary and nutritional factors affect the eye. The ocular system is perhaps one of the least studied organs in diet and nutrition, yet the consequences of vision loss are devastating. There are a range of ocular defects that have either their origin in nutritional deficiencies/excess or have been shown to respond favorably to nutritional components. Featuring a new section on animal model studies where both the ocular problem and dietary remedies can be varied, there are also new chapters on dietary supplements.

  • Introduction to Addiction

    Addiction, Animal Models, and Theories
    • 1 Edición
    • Volumen 1
    • George F. Koob + 3 más
    • Inglés
    Introduction to Addiction, Volume One in the series, introduces the reader to the study of neurobiology of addiction by clearly defining addiction and its neuroadaptational views. This volume includes thorough descriptions of the various animal models applicable to the study of addiction, including Animal Models of the Binge-Intoxication Stage of the Addiction Cycle and Animal Models of Vulnerability to Addiction. The book's authors also include a section on numerous neurobiological theories that aid in the understanding of addiction, including dopamine, prefrontal cortex and relapse.

  • Advances in Treatment and Management in Surgical Endocrinology

    • 1 Edición
    • Alexander L. Shifrin
    • Inglés
    Up-to-date and evidence-based, Advances in Treatment and Management in Surgical Endocrinology provides an overview of recent developments regarding the most prevalent endocrine disorders. A concise, easy-to-read reference for endocrinologists and endocrine surgeons, this timely reference includes an overview of each disorder as well as diagnosis, management, treatment, prognosis, and a summary by a renowned expert who has contributed to the most current literature.

  • Sustainable Food Supply Chains

    Planning, Design, and Control through Interdisciplinary Methodologies
    • 1 Edición
    • Riccardo Accorsi + 1 más
    • Inglés
    Sustainable Food Supply Chains: Planning, Design, and Control through Interdisciplinary Methodologies provides integrated and practicable solutions that aid planners and entrepreneurs in the design and optimization of food production-distribut... systems and operations and drives change toward sustainable food ecosystems. With synthesized coverage of the academic literature, this book integrates the quantitative models and tools that address each step of food supply chain operations to provide readers with easy access to support-decision quantitative and practicable methods. Broken into three parts, the book begins with an introduction and problem statement.　 The second part presents quantitative models and tools as an integrated framework for the food supply chain system and operations design. The book concludes with the presentation of case studies and applications focused on specific food chains. Sustainable Food Supply Chains: Planning, Design, and Control through Interdisciplinary Methodologies will be an indispensable resource for food scientists, practitioners and graduate students studying food systems and other related disciplines.

  • Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

    The Chemical and Pharmacological Basis of their Action
    • 1 Edición
    • Solomon Habtemariam
    • Inglés
    Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/developmen... nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries.

  • Parasiticide Screening

    Volume 2: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods
    • 1 Edición
    • Alan A. Marchiondo + 2 más
    • Inglés
    Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestatio... Methods, Volume Two presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds.

  • Biomarkers, Diagnostics and Precision Medicine in the Drug Industry

    Critical Challenges, Limitations and Roadmaps for the Best Practices
    • 1 Edición
    • Abdel Halim
    • Inglés
    The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline, as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerate the time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. This book aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies, which includes standard-of-care approved assays as well as for-investigational-... and for-research-use-onl... assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. This book serves as a reference to drug developers, IVD providers, clinical labs, healthcare givers, academicians, and researchers for best practices to help increase the probability of success in drug development and improve patient management.

  • Parasiticide Screening

    Volume 1: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestation Methods
    • 1 Edición
    • Alan A. Marchiondo + 2 más
    • Inglés
    Parasiticide Discovery: In Vitro and In Vivo Tests with Relevant Parasite Rearing and Host Infection/Infestatio... Methods, Volume One presents valuable screening methods that have led to the discovery of the majority of parasiticides commercialized in the animal health industry. As much of the knowledge of parasiticide discovery methods is being lost in the animal health industry as seasoned parasitologists retire, this book serves to preserve valuable methods that have led to the discovery of the majority of parasiticides commercialized in animal health, also giving insights into the in vitro and in vivo methods used to identify the parasiticide activity of compounds.

  • Food Quality and Shelf Life

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Food Quality and Shelf Life covers all aspects and challenges of food preservation, packaging and shelf-life. It provides information on the most important pillars in the field, starting with active and smart packaging materials, novel technologies, and control tools in all stages between production and consumer. The book gives emphasis to methodological approaches for sensory shelf-life estimation and the impact of packaging on sensorial properties. Researchers and professionals alike will find this reference useful, especially those who are interested in the performance evaluation of future packaging for fresh produce in the cold chain and temperature management in the supply chain.

  • Alternative Swine Management Systems

    • 1 Edición
    • Ioan Hutu + 1 más
    • Inglés
    Alternative Swine Management Systems examines technologically humane substitutions for swine production, focusing specifically on hoop structure systems. Benefits of these alternatives include enhanced animal welfare and reduced capital cost. From small holders involved in low input pig farms, to larger commercial operations, this book instructs users on new technology to improve the quality of animal production, animal welfare and environmental protection points.

  • Innovative Thermal and Non-Thermal Processing, Bioaccessibility and Bioavailability of Nutrients and Bioactive Compounds

    • 1 Edición
    • Francisco J. Barba + 3 más
    • Inglés
    Innovative Thermal and Nonthermal Processing, Bioacessibility and Bioavailability of Nutrients and Bioactive Compounds presents the implications of conventional and innovative processing on the nutritional and health aspects of food products. Chapters cover the relationship between gastronomic science, nutrition and food science in the development of healthy products, introduce the most commonly used conventional and innovative approaches to preserve foods and extract valuable compounds, describe how processing affects bioavailability and bioaccessibility of lipids, particularly fatty acids, protein, amino acids and carbohydrates, and discuss how processing affects bioavailability and bioaccessibility of minerals, water-soluble vitamins, and fat soluble vitamins. Final sections cover processing, bioavailability and bioaccessibility of bioactive compounds, describing how processing (conventional and non-conventional) is affecting to bioavailability and bioaccessibility of bioactive sulphur compounds, polyphenols, flavonoids, and bioactive peptides.

  • Nutrients in Beverages

    Volume 12: The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Nutrients in Beverages, Volume Twelve, in the Science of Beverages series, introduces the role of nutrients in beverages and provides details into the biological effects of beverage ingredients by presenting their nutritional properties and characterization. This scientific reference covers both the current state-of-the-art and future trends in the beverage industry, and is designed as a comprehensive guide to this area of research. Detailed research information is presented to not only help researchers and students understand the nature of the challenges associated with incorporating nutrients, but to also help strengthen the knowledge transfer between research institutions and industry.

  • Smart Bioremediation Technologies

    Microbial Enzymes
    • 1 Edición
    • Pankaj Bhatt
    • Inglés
    Smart Bioremediation Technologies: Microbial Enzymes provides insights into the complex behavior of enzymes and identifies metabolites and their degradation pathways. It will help readers work towards solutions for sustainable medicine and environmental pollution. The book highlights the microbial enzymes that have replaced many plant and animal enzymes, also presenting their applications in varying industries, including pharmaceuticals, genetic engineering, biofuels, diagnostics and therapy. In addition, new methods, including genomics and metagenomics, are being employed for the discovery of new enzymes from microbes. This book brings all of these topics together, representing the first resource on how to solve problems in bioremediation.

  • Safety and Practice for Organic Food

    • 1 Edición
    • Debabrata Biswas + 1 más
    • Inglés
    Safety and Practice for Organic Food covers current food safety issues and trends. It provides detailed information on all organic and pasture practices including produce-only, farm-animal-only or integrated crop-livestock farming, as well as the impact of these practices on food safety and foodborne infections. The book explores food products that organic, integrated and traditional farming systems are contributing to consumers. As the demand for organic food products grows faster than ever, this book discusses current and improved practices for safer products. Moreover, the book explores progressive directions, such as the application of next-generation sequencing and genomics to aid in the understanding of the microbial ecology of the agro-environment and how farmer education can contribute to sustainable and safe food. Safety and Practice for Organic Food is a unique source of organic agricultural practices and food production for researchers, academics and professionals at agriculture-based universities and colleges who are involved in food science, animal sciences including poultry science, food safety, food microbiology, plant science and agricultural extension. This book is also an excellent source of information for regulators and federal government officials (USDA, FDA, EPA) and the food processing industry.

  • Single-Cell Omics

    Volume 1: Technological Advances and Applications
    • 1 Edición
    • Debmalya Barh + 1 más
    • Inglés
    Single-Cell Omics: Volume 1: Technological Advances and Applications provides the latest technological developments and applications of single-cell technologies in the field of biomedicine. In the current era of precision medicine, the single-cell omics technology is highly promising due to its potential in diagnosis, prognosis and therapeutics. Sections in the book cover single-cell omics research and applications, diverse technologies applied in the topic, such as pangenomics, metabolomics, and multi-omics of single cells, data analysis, and several applications of single-cell omics within the biomedical field, for example in cancer, metabolic and neuro diseases, immunology, pharmacogenomics, personalized medicine and reproductive health. This book is a valuable source for bioinformaticians, molecular diagnostic researchers, clinicians and members of the biomedical field who are interested in understanding more about single-cell omics and its potential for research and diagnosis.

  • Advances in Genetics

    • 1 Edición
    • Volumen 104
    • Inglés
    Advances in Genetics, Volume 104, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

  • Functional and Medicinal Beverages

    Volume 11: The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Functional and Medicinal Beverages, Volume Eleven, in the Science of Beverages series, discusses one of the fastest growing sectors in the food industry. As the need for research and development increases based on consumer demand, the information in this volume is essential. This reference includes the latest research trends, nutritive and medicinal ingredients, and analytical techniques to identify health beneficial elements. The contents of the book will bring readers up-to-date on the field, thus making it useful for researchers and graduate students in various fields across the food sciences and technology.

  • Membrane Transporters in the Pathogenesis of Cardiovascular and Lung Disorders

    • 1 Edición
    • Volumen 83
    • Inglés
    Membrane Transporters in the Pathogenesis of Cardiovascular and Lung Disorders, Volume 83, the latest release in the Current Topics in Membranes series, highlights new advances in the field, with this volume presenting chapters from recognized experts on topics such as cardiotonic steroids, Na+, K+ pumps and vascular fibrosis, purinergic signaling in the lung, structural models of a2-subunit N-termini and binding interfaces, ubiquitous and cell type-specific transcriptomic changes triggered by dissipation of monovalent cation gradients, the Na, K-ATPase alpha2 isoform in cardiovascular pathologies, the role of cell swelling and volume-sensitive ion channels in stroke pathology, structure-function relationships in the renal NaCl cotransporter, and more.

  • The Core Model

    A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care
    • 1 Edición
    • Ibis Sanchez Serrano
    • Inglés
    The Core Model: A Collaborative Paradigm for the Pharmaceutical Industry and Global Health Care develops the innovative core model, an organizational research and design paradigm and economic theory that proposes a collaborative approach to resolving global health issues and improving the productivity of drug development. The model proposes that scientific collaboration does not occur in an unstructured manner, but actually takes place within a highly structured order where knowledge is transferred, integrated and finally translated into commercial products. An understanding of this model will help solve the global pharmaceutical industry´s productivity problems and address important global health care and economic issues. This book is useful to researchers, advanced students, regulators, and management in pharmaceutical industries, as well as healthcare professionals, those working in health economics, and those interested in scientific innovation processes.

  • Emotion and Cognition

    • 1 Edición
    • Volumen 247
    • Inglés
    Emotion and Cognition, Volume 246, consists of 16 chapters on recent scientific advances in emotion and cognition research. The chapters include theoretical, review, and empirical chapters presenting original data on interactions between emotion and cognition. Chapters touch on a variety of topics, including Common and different mechanisms underlying the processing of extrinsic and intrinsic emotion, Looming fear stimuli broadens attention in a local-global letter task, Reading thoughts and feelings in other people – how age shapes empathic accuracy, How does aging influence emotion-cognition links?, and The Motivational Dimensional Model of affect: A review of the past 10 years, and more.

  • Pharmacoepigenetics

    • 1 Edición
    • Volumen 10
    • Ramón Cacabelos
    • Inglés
    Pharmacoepigenetics provides a comprehensive volume on the role of epigenetics and epigenomics in drug discovery and development, providing a detailed, but accessible, view of the field, from basic principles, to applications in disease therapeutics. Leading international researchers from across academia, clinical settings and the pharmaceutical industry discuss the influence of epigenetics and epigenomics in human pathology, epigenetic biomarkers for disease prediction, diagnosis, and treatment, current epigenetic drugs, and the application of epigenetic procedures in drug development. Throughout the book, chapter authors offer a balanced and objective discussion of the future of pharmacoepigenetics and its crucial contribution to the growth of precision and personalized medicine.

  • Encyclopedia of Tissue Engineering and Regenerative Medicine

    • 1 Edición
    • Rui L. Reis
    • Inglés
    Encyclopedia of Tissue Engineering and Regenerative Medicine, Three Volume Set provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine.

  • NETosis

    Immunity, Pathogenesis and Therapeutics
    • 1 Edición
    • Geeta Rai
    • Inglés
    NETosis: Immunity, Pathogenesis and Therapeutics takes a focused approach to the clinical aspects of NETosis and drug development, bringing critical findings. Chapters introduce NETosis, consider mechanisms and antimicrobial strategies regulating NETosis, examine NETosis in neonates, explore the role of NETosis in autoimmunity, delve into NETosis and other diseases, and present therapeutic approaches for dysregulated NETosis. Since Brinkamm, et al, discovered an unrecognized neutrophil anti-microbial mechanism responsible for the extracellular killing of invading pathogens in 2004, the novel process in which nuclear chromatin de-condenses and DNA is ejected into the extra cellular environment, trapping and inactivating tissue pathogens has rapidly evolved.

  • Nutraceutical and Functional Food Regulations in the United States and around the World

    • 3 Edición
    • Debasis Bagchi
    • Inglés
    Nutraceutical and Functional Food Regulations in the United States and Around the World, Third Edition addresses the latest regulatory requirements designed to ensure the safe production and delivery of these valuable classes of foods. The book is well recognized, showing how food and nutrition play a critical role in enhancing human performance, and in overall health. The book discusses the scope, importance and continuing growth opportunities in the nutraceutical and functional food industries, exploring the acceptance and demand for these products, regulatory hurdles, the intricate aspects of manufacturing procedures, quality control, global regulatory norms and guidelines.

  • The Mechanics of Inhaled Pharmaceutical Aerosols

    An Introduction
    • 2 Edición
    • Warren H. Finlay
    • Inglés
    The Mechanics of Inhaled Pharmaceutical Aerosols: An Introduction, Second Edition provides a concise, but thorough exposition of fundamental concepts in the field of pharmaceutical aerosols. This revised edition will allow researchers in the field to gain a thorough understanding of the field from first principles, allowing them to understand, design, develop and improve inhaled pharmaceutical aerosol devices and therapies. Chapters consider mechanics and deposition, specifically in the respiratory tract, while others discuss the mechanics associated with the three existing types of pharmaceutical inhalation devices. This text will be very useful for academics and for courses taught at both undergraduate and graduate levels. Because of the interdisciplinary nature of this book, it will also serve a wide audience that includes engineers and scientists involved with inhaled aerosol therapies.

  • Saving Food

    Production, Supply Chain, Food Waste and Food Consumption
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Saving Food: Production, Supply Chain, Food Waste and Food Consumption presents the latest developments on food loss and waste. Emphasis is placed on global issues, the environmental impacts of food consumption and wasted food, wasted nutrients, raising awareness via collaborative networks and actions, the effect of food governance and policy in food losses, promotion of sustainable food consumption, food redistribution, optimizing agricultural practices, the concept of zero waste, food security and sustainable land management, optimizing food supply and cold chains, food safety in supply chain management, non-thermal food processing/preservat... technologies, food waste prevention/reduction... food waste valorization and recovery. Intended to be a guide for all segments of the food industry aiming to adapt or further develop zero waste strategies, this book analyzes the problem of food waste from every angle and provides critical information on how to minimize waste.

  • Taxonomic Guide to Infectious Diseases

    Understanding the Biologic Classes of Pathogenic Organisms
    • 2 Edición
    • Jules J. Berman
    • Inglés
    Taxonomic Guide to Infectious Diseases: Understanding the Biologic Classes of Pathogenic Organisms, Second Edition tackles the complexity of clinical microbiology by assigning every infectious organism to one of 40+ taxonomic classes and providing a description of the defining traits that apply to all the organisms within each class. This edition is an updated, revised and greatly expanded guide to the classes of organisms that infect humans. This book will provide students and clinicians alike with a simplified way to understand the complex fields of clinical microbiology and parasitology.

  • Metabolism, Structure and Function of Plant Tetrapyrroles: Introduction, Microbial and Eukaryotic Chlorophyll Synthesis and Catabolism

    • 1 Edición
    • Volumen 90
    • Inglés
    Metabolism, Structure and Function of Plant Tetrapyrroles, Volume 90, the latest release in the Advances in Botanical Research series is a compilation of the current state-of-the-art on the topic. Chapters in this new release cover Tetrapyrrole Pigments of Photosynthetic Antennae and Reaction Centers of Higher Plants: Biochemistry, Biophysics, Functions, Molecular Mechanism of Antenna Regulation, Applications, Chlorophyll c: Synthesis, Occurrence, Light-Harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Proteins (FCP), Chlorophyll d and f: Synthesis, Occurrence, Light-harvesting, Absorbance, Excitation Properties, Pigment Organization in Chlorophyll-Binding Protein Complexes, Analysis of Chlorophyll, Precursors and Derivatives by New High-Performance Liquid Chromatography and Mass Spectrometry, and much more.

  • The Immortal Germline

    • 1 Edición
    • Volumen 135
    • Inglés
    The Immortal Germline, Volume 135 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Balbiani body, germ plasm and polarity, Wolbachia and the germline, Human germ line biology, Reproduction/immunit... and sperm success, Mammalian spermatogenesis, Reproduction/regener... and germ cells in planarians, Germline stem cell homeostasis, Germline soma interactions/sex determination, Reconstituting the mouse germ-cell specification pathway in vitro, Maternal Germ line inheritance of mitochondria, Transposon strategies, and more.

  • Proteins: Sustainable Source, Processing and Applications

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Proteins: Sustainable Source, Processing and Applications addresses sustainable proteins, with an emphasis on proteins of animal origin, plant-based and insect proteins, microalgal single cell proteins, extraction, production, the stability and bioengineering of proteins, food applications (e.g. encapsulation, films and coatings), consumer behavior and sustainable consumption. Written in a scientific manner to meet the needs of chemists, food scientists, technologists, new product developers and academics, this book addresses the health effects and properties of proteins, highlights sustainable sources, processes and consumption models, and analyzes the potentiality of already commercialized processes and products. This book is an integral resource that supports the current applications of proteins in the food industry, along with those that are currently under development.

  • Pathophysiology of Ischemia Reperfusion Injury and Use of Fingolimod in Cardioprotection

    • 1 Edición
    • Naseer Ahmed
    • Inglés
    Pathophysiology of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is a deep examination into the mechanisms of myocardial ischemiareperfusion injury and role of fingolimod as a cardioprotective agent through its antioxidant, anti-apoptotic and anti-inflammatory effects. Dr. Ahmed explore the physiology and pathophysiology of myocardial metabolism under normal and ischemic conditions and focused on pharmacological cardioprotection. They provide a concise, yet rigorous discussion of Ischemia-Reperfusion Injury, Myocardial Ischemia during Circulatory Arrest, Myocardial Reperfusion, Myocardial Protection related to Ischemia-Reperfusion Injury and Role of Fingolimod in Cardioprotection.Pat... of Ischemia-Reperfusion Injury and Use of Fingolimod in Cardioprotection is ideal for researchers, cardiovascular scientists, and clinical pharmacologists to further work in this challenging area and apply this knowledge to clinical trials for cardioprotection.

  • Chemical and Synthetic Biology Approaches to Understand Cellular Functions - Part B

    • 1 Edición
    • Volumen 622
    • Inglés
    Chemical and Synthetic Biology Approaches To Understand Cellular Functions - Part B, Volume 622, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting chapters that cover the Design of optogenetic proteins, the Application of optogenetic proteins, Antibody aggregation mechanism probed by a fluorescently-labele... antibody with fluorescence correlation spectroscopy, Bimane labeling of B-arrestins to measure their interaction with GPCRs, Reversible biotinylation of proteins for investigating their interaction with partners, Chemical biology approaches to study RNA cytidine acetylation, Salt sensitive intein in robotic production of peptides, and much more.

  • Food Applications of Nanotechnology

    • 1 Edición
    • Volumen 88
    • Inglés
    Food Applications of Nanotechnology, Volume 88, consolidates the literature on recent developments in nanotechnology, addressing production, safety and nutritional aspects pertaining to foods and nutraceuticals. Chapters in this new release include Assembled protein nanoparticles in food and nutrition applications, Nano-scale carbohydrate Materials in food/nutrition/agric... applications, Nanotechnology-based colloidal delivery systems in foods, Electrospinning and Electrospraying in food, Bioavailability of nanotechnology-based bioactives and nutraceuticals, and more.

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