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Elsevier

Libros en Ciencias de la Vida

  • Advances in Virus Research

    • 1 Edición
    • Volumen 124
    • Inglés
    Advances in Virus Research, Volume 124 in this ongoing seriesseries, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Emerging and Reemerging Viral Threats to Pregnancy and Nomenclature for vertically transmitted plant.

  • Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer

    • 1 Edición
    • Volumen 207
    • Inglés
    Advanced Methodologies to Study and Enhance Cellular Cytotoxicity Against Cancer, Volume 207 covers the latest techniques and strategies used to investigate and boost cytotoxic activity in cells targeting cancer. Chapters include An ex vivo assay to assess CAR T cell cytotoxicity in viable tumor tissues using a two-step staining protocol, New protocol to measure mitochondria polarization/functio... at the immunological synapse, Analysis of CAR-T cell–mediated cytotoxicity in solid tumor models, Investigation of the in vitro lytic capacity of CAR-T by microscopyal, Antigen-specific T cell cytotoxicity toward target tumor cells, In vitro expansion of stem-like memory T cells via D-mannose supplementation, and much more.Additional chapters explore High-throughput time-lapse imaging of B16 target cell killing by ovalbumin-specific CD8+ T cells, Evaluation of an intracellular magneto-mechanical approach for regulating dendritic cell activation, Analyzing the effect of NK cells on in-vivo models of tumor dissemination by digital pathology and flow cytometry, Super-resolution imaging of the NK cell synapse on supported lipid bilayers using MINFLUX nanoscopy, ASSESSMENT OF NK CELL CYTOTOXICITY INDUCED BY IL-15 BASED IMMUNOTHERAPY AGAINST CANCER CELLS, Combined phenotyping and functional analysis of isolated human natural killer cells using spectral flow cytometry, and much more.

  • Working Memory

    • 1 Edición
    • Christos Constantinidis
    • Inglés
    Working Memory provides a comprehensive examination of the neural basis of working memory, defined as the cognitive ability to maintain information over short periods. This volume addresses the need for an accessible, yet thorough resource that bridges cognitive psychology and neuroscience, focusing on how neuronal activity in the cerebral cortex underpins memory processes. It is primarily designed for undergraduate and early graduate students in neuroscience, psychology, and related fields such as cognitive science and biomedical engineering. Topics covered include brain anatomy, organization, neurophysiology, and neuroimaging techniques, all contextualized within the study of working memory.

  • Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies

    • 1 Edición
    • Shuvomoy Banerjee + 1 más
    • Inglés
    Novel and Innovative Drug Delivery Systems to Overcome Chemoresistance in Human Malignancies addresses the critical challenge of cancer chemoresistance, synthesizing insights from cancer biology, molecular biology, biotechnology, and nanotechnology. The book explores the complex mechanisms underlying drug resistance, including alterations in key signaling pathways and the tumor microenvironment's role in cancer cell survival. It highlights advancements in drug delivery technologies, such as nanomedicine and biomimetic strategies, which enhance drug targeting and minimize off-target effects. The integration of techniques like CRISPR-Cas9 and artificial intelligence in developing next-generation therapies is also emphasized. For an academic audience, this book serves as an essential resource to foster interdisciplinary collaboration in cancer research. It equips researchers, clinicians, and industry professionals with the knowledge needed to navigate the evolving landscape of cancer therapeutics, addressing critical challenges in drug delivery and chemoresistance to improve patient outcomes.

  • Nutrition e Neurotoxicology Part A

    • 1 Edición
    • Volumen 15
    • Inglés
    Nutrition and Neurotoxicity, Volume Fifteen-Part A highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including the Effect of toluene on memory: A focus on humans, experimental models and treatment approaches, Neurotoxicological Mechanisms of Ethanol, Neurobehavioral Aspects and Methodology of Solvents, Organic solvents and neurodegenerative diseases: exploring a possible link, Neurotoxicity of propylene ethers.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 197
    • Inglés
    Advances in Agronomy, Volume 197, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors. Chapters in this new release include Distribution, characteristics and management of Andisols for agricultural production and carbon sequestration, Reducing Emissions from Fertilizers: Opportunities and Challenges, The Unintended Consequences of N: Addressing Pollution from Nitrogenous Fertilizers with Potential Remedies, and Reconciling soil health benefits with carbon sequestration value of organic carbonaceous amendments.

  • Microbial and Biochar Technology for Waste Valorization

    • 1 Edición
    • Maulin P. Shah + 2 más
    • Inglés
    Microbial and Biochar Technology for Waste Valorization delves into the innovative integration of microbial and biochar technologies, presenting a compelling case for their combined utilization in waste reuse to aid environmental sustainability. The book opens with a discussion of current and emerging environmental issues and the need for implementing integrated microbe-biochar processes. Initial chapters explore the fundamentals of biochar, its sources, synthesis routes, characterization methods, its impact on soil, environment, and water microbiomes, and approaches to biochar production.The book then delves deeper into its role in environmental remediation, its suitability as a microbe carrier, and the combination of biochar and microbes for various applications, including microbial fuel cells, biofertilizer, biopesticide, and water treatment processes. Final sections highlight the use of machine learning and AI for predicting biochar characteristics, biochar's potential in promoting a circular economy and carbon neutrality, and future directions for biochar-microbe applications.

  • Vector-Borne Diseases

    • 1 Edición
    • Volumen 58
    • Inglés
    Vector Borne Diseases, Volume 58 in the Methods in Microbiology series, highlights new advances in the field, with this new volume presenting interesting written by an international board of authors. Chapters in this new release cover Methods for Isolation and Characterization of Arthropod Hemocytes, Tick-to-Host Transmission of B. burgdorferi: In Vitro and In Vivo Methodologies, Decoding the Zika Virus outbreak and Infection Dynamics, Visual and molecular methods for studying pathogen persistence in flea vectors, Lipidomic Analysis of Virus-infected Cells, and Implementation of the Neutropenic Thigh Infection Murine Model with Francsiella tularensis for Development of New Antibacterials.

  • Biomarkers for Cancer Screening, Diagnosis and Targeted Therapeutic Approaches

    • 1 Edición
    • Volumen 170
    • Inglés
    Biomarkers for Cancer Screening, Diagnosis and Targeted Therapeutic Approaches, Volume 170 provides an integrated overview of the current state and future directions of biomarker research in oncology. The book bridges fundamental molecular insights with clinical applications, emphasizing how biomarkers are transforming cancer detection, diagnosis, prognosis, and personalized treatment strategies. Chapters cover an Introduction to cancer biomarkers and current research, Role of Biomarkers for cancer detection, diagnosis, and treatment, Classification of Cancer Biomarkers based on treatment strategies, Predictive, Prognosis and Diagnostic Cancer Biomarker in cancer therapeutic approaches, Biomarkers for targeted therapy and treatment decision-making, and much more.Additional sections delve in to Emerging trends in cancer biomarker and their clinical effect on personalized treatment, Recent advances in detection techniques regarding predictive, prognostic and diagnostic biomarkers in solid cancers and its future challenges, Recent advances in detection techniques regarding predictive, prognostic and diagnostic biomarkers in body fluids and its future challenges, Emerging biomarkers for non-invasive cancer diagnosis and treatment, and more. The brings together recent advancements in molecular diagnostics, predictive and prognostic markers, and targeted therapeutic development across a wide range of cancer types.

  • Pesticides and Neurotoxicant Exposures

    Impacts of Neurodevelopment and Long-Term Brain Health
    • 1 Edición
    • Neha Gogia + 1 más
    • Inglés
    Pesticides and Neurotoxicant Exposures: Impacts of Neurodevelopment and Long-Term Brain Health explores neuroscience research, revealing how chronic pesticide exposure contributes to neurodegenerative diseases and cognitive decline. This new volume synthesizes findings on the mechanisms of pesticide-induced neurotoxicity and its impact on brain health. Targeted at researchers, clinicians, and policymakers, the book explores gaps in knowledge and the urgent need for improved regulation to protect vulnerable populations. By bridging scientific insights with public health, the book aims to advance understanding and prevention of pesticide-related neurological disorders.

  • Cytokine-Based immunotherapy Part B

    • 1 Edición
    • Volumen 401
    • Inglés
    Cytokine-Based immunotherapy: Part B, Volume 401 delves into the intricate world of cytokines, the vital signaling proteins that orchestrate the immune response and their pivotal role in modulating various immune functions. From fundamental mechanisms to their therapeutic applications, this book offers a thorough examination of the latest trends and developments in leveraging cytokines for immunotherapy. Chapters cover Cytokine-based immunotherapy in pancreatic cancer, IL-33 and its pleiotropic role in cancer, Immunocytokines based on IL-12 for cancer therapy: enhancing efficacy and reducing toxicity, Cytokine network in immunosuppression and tumor development in glioblastoma, The Double-Edged Role of Interferon Gamma in Cancer Immunity, and much more.An additional section covers Engineering Interleukin-10 for Therapeutic Applications, IL-23 Blockade: A Strategy for Relieving Inflammatory Diseases. Targeting TNF-alpha examines the immunotherapeutic approach for alleviating neuropathic pain. The key role of immunomodulatory cytokines for the development of novel nk cell-based cancer therapies focuses on the importance of cytokines in developing new cancer treatments. Finally, complexities in the clinical development of TGFβ inhibitors covers the challenges in creating inhibitors for TGFβ.

  • Artificial Intelligence Interventions in Agriculture, Food and Health Sectors

    • 1 Edición
    • Narashans Alok Sagar + 4 más
    • Inglés
    Artificial Intelligence Interventions in Agriculture, Food and Health Sectors provides an integrated connection among agriculture, food, nutrition, and health sectors, compiling the history and evolution of AI, the scope of AI in the agricultural and food sectors, AI applications in the food processing and supply chain, and the role of AI in the food safety and healthcare industry. Edited by a multidisciplinary team, this book is a unique resource covering the innovative concepts of AI in the agriculture and food sectors, while providing useful insights to students, scientists, progressive farmers, food processing, and healthcare industries about the scope of AI applications.Users will find this to be a single platform for progressive farmers, food processing researchers, and healthcare professionals who are interested in learning about the potential of AI across a broad range of sectors. The book emphasizes the significance of stakeholder collaboration across disciplines to properly utilize the strengths of AI and handle its limitations.

  • Women and Health

    • 3 Edición
    • Rebecca Troisi + 3 más
    • Inglés
    Women and Health, 3rd Edition, addresses health issues affecting women of all ages from adolescence through maturity. Extending far beyond other books on women’s health, which tend to focus on reproductive health alone, this book covers key issues ranging from osteoporosis to breast cancer, domestic violence, sexually transmitted diseases, occupational hazards, eating disorders, heart disease and other chronic illnesses, substance abuse, and societal and behavioral influences on health.In this third edition of Women and Health, the chapters incorporate issues that affect women across the life course with a special emphasis on the health of mid-life and older women. Changes in the field of women’s health since the first and second editions, for example, in genetics and the impact of sex and gender on health, are represented with the latest scientific findings and controversies.This book provides a comprehensive compendium of the epidemiology of health conditions affecting women internationally and over the life course for the lay reader, clinician, and health research scientist.

  • Exploring Nanocarriers in Breast Cancer Management

    • 1 Edición
    • Amarjitsing Rajput + 3 más
    • Inglés
    Exploring Nanocarriers in Breast Cancer Management comprehensively delves into the realm of nanocarrier systems, which have shown immense potential in the management of breast cancer. The scope of this book encompasses a thorough exploration of various nanocarrier systems, including, amongst others, liposomes, niosomes, and microneedles. It highlights recent advancements in these systems and their promising results in breast cancer treatment. Additionally, the book addresses the crucial aspects of toxicity and regulatory considerations associated with nanocarriers. It aims to provide a foundational understanding of nanocarriers, their unique features, and their significant role in breast cancer management.As breast cancer remains one of the most prevalent forms of cancer today, with no definitive cure currently available, this book is an essential resource for researchers, healthcare professionals, and anyone interested in cutting-edge developments in breast cancer treatment.

  • Viruses

    Molecular Biology, Host Interactions, and Applications to Biotechnology
    • 2 Edición
    • Paula Tennant + 2 más
    • Inglés
    Viruses: Molecular Biology, Host Interactions, and Applications to Biotechnology, Second Edition provides an update on recent developments and perspectives, including coverage on the history of viruses, their structure, the organization of their genomes, and strategies in replication and expression. It emphasizes their diversity and versatility, how they cause disease, and how their human, animal, and plant hosts react. Sections also explore the beneficial aspects of viruses and how they can be utilized as tools and targets for biotechnological applications. This edition will appeal to a wide audience, including academics, researchers, and students studying the molecular biology and applications of viruses.Advances in technologies and enhanced surveillance have facilitated the monitoring of virus evolution, transmission dynamics, and pathogenesis. Coupled with the experiences of the COVID-19 pandemic, we have a better understanding of the interconnectedness of human, animal, and environmental health and the impact viruses have on society and the economy. This new release updates on many critical aspects of viruses and recent research.

  • Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment

    • 1 Edición
    • Vincenzo Dentamaro + 2 más
    • Inglés
    Behavioral Biometrics and Artificial Intelligence for Neurodegenerative Diseases Assessment explores cutting-edge, non-invasive techniques for the early detection of neurodegenerative diseases. The book focuses on behavioral biometrics, which analyzes patterns in a person’s actions rather than directly measurable traits. By utilizing artificial intelligence methods—like machine learning and deep neural networks—it enables the observation of subtle changes in gait, handwriting, and speech. These advanced approaches offer promise for earlier and more accurate diagnosis, potentially improving outcomes for millions affected by conditions such as Alzheimer’s and Parkinson’s diseases through timely intervention and personalized care.In addition to its core coverage, the book delves into the practical applications of wearable sensors and the use of everyday devices like smartphones and tablets in assessments. It provides comprehensive chapters on how these technologies can aid clinicians and researchers in monitoring disease progression outside traditional clinical settings.

  • Step-by-step Approach to the Radiological Evaluation of Arthritis

    • 1 Edición
    • Muthusamy Chandramohan + 1 más
    • Inglés
    Step-by-step Approach in the Radiological Evaluation of Arthritis is a concise, practical reference source for the evaluation and interpretation of arthritis images. The book begins by briefly reviewing relevant anatomy, clinical and biochemical considerations. Subsequent chapters analyze specific arthritis indications in radiographic images using a simple, systematic approach. The book presents guidelines for when and when not to consider other advanced imaging techniques. Final chapters are devoted to troubleshooting strategies and key not-to-miss indications in rheumatic imaging. X-rays play a crucial role in the diagnosis and management of arthritis. This book’s clear and simple explanations of the subtleties and distinctions in arthritis imaging aims to improve investigative accuracy and aid healthcare professionals in monitoring disease progression and driving treatment decisions. Clinicians and radiologists in rheumatology as well as orthopedics will find certain value in integrating this must-have handbook into their daily practice.

  • Building Resilient Water and Food Systems under Climate Change

    • 1 Edición
    • Thendiyath Roshni + 3 más
    • Inglés
    Building Resilient Water and Food Systems Under Climate Change aims to help readers understand and implement strategies to build resilient communities that can ensure sustainable access to both food systems and water resources. The book examines the impact of climate change on food and water security and explores how communities can adapt to these challenges. It provides an in-depth analysis of climate change science, focusing on its effects on agriculture, water resources, and ecosystems. Additionally, the book showcases case studies of communities that have successfully employed resilience strategies by integrating traditional and local knowledge systems with modern techniques. Readers will find practical solutions for managing risks and building sustainable, climate-resilient systems. By combining theoretical insights with real-world examples, this comprehensive guide is designed for policymakers, researchers, and community leaders to effectively safeguard essential resources at both macro and micro levels in the face of climate change.

  • Silicon as a Sustainable Solution for Mitigating Abiotic and Biotic Stress in Plants

    • 1 Edición
    • Volumen 118
    • Inglés
    Silicon as a Sustainable Solution for Mitigating Abiotic and Biotic Stress in Plants, Volume 118 in the Advances in Botanical Research series, presents interesting chapters on a variety of topics, including Silicon in Soil and Plant, Silicon Transporters in Agronomic Crops, The Role of Silicon in Sustainable Disease Management of Monocot Plants, Silicon in the Management of Diseases in Dicot Crops, Silicon and Biocontrol Agents for Plant Growth and Control of Diseases in Rice, Silicon for the Control of Insect Herbivores in Agronomic Crops, Silicon-Driven Phenotypic Induction Enhances Physiological Tolerance to Water Deficit and Waterlogging in Agronomic Crops, and much more.Additional sections cover Silicon Nutrition for Sugarcane Production, Silicon Nutrition of Agronomic Crops, Physiological Aspects of Silicon in Plants under Stress, and Alleviation of Heavy Metal Stress in Plants by Silicon.

  • Sports Medicine and the Pelvic Floor

    Science to Practice
    • 1 Edición
    • Gráinne M. Donnelly
    • Inglés
    Sports Medicine and the Pelvic Floor: Science to Practice shines a spotlight on a critical but often overlooked aspect of female athlete health: the pelvic floor. Bringing together the expertise of international clinicians and researchers, this book highlights persistent gaps in knowledge and practice, offering valuable direction for future research. It educates professionals on how to effectively screen, treat, and rehabilitate athletes, emphasizing that pelvic floor dysfunction can profoundly impact engagement, athletic performance, and overall well-being. By addressing this traditionally taboo subject, the authors provide evidence-based insights that call for the pelvic floor to be considered as essential in sports medicine.Sections discuss practical strategies for screening and supporting athletes, managing or alleviating symptoms, and ensuring a safe return to sport, all while prioritizing long-term pelvic health. This is an indispensable resource for anyone working with female athletes, blending science and clinical experience to advance care in this vital area.

  • Neurological Assessment Made Easy

    A Step-by-Step Guide for Physiotherapists
    • 1 Edición
    • Vishal Verma
    • Inglés
    Neurological Assessment Made Easy: A Step-by-Step Guide for Physiotherapists delves into the intricacies of neurological assessment, covering a wide range of topics such as sensory and motor function, reflexes, coordination, balance, and cognition. This text provides physiotherapists and clinicians with a comprehensive framework to systematically assess and evaluate the neurological status of their patients. This book provides practical strategies and tips to navigate challenges effectively, ensuring accurate and meaningful assessment results and emphasizes the importance of effective neurological assessment in guiding the development of personalized treatment plans.

  • A Quick Reference to Obstetric Anesthesia

    • 1 Edición
    • Adithya Devadas Bhat + 1 más
    • Inglés
    A Quick Reference to Obstetric Anesthesia is a comprehensive resource on the latest in anesthetic care for the pregnant patients. It covers the newest evidence on various critical topics in obstetric anesthesia, and the inclusion of recommended perioperative protocols provides definitive references for optimal care. This book serves as an “in the moment” tool for solving challenging clinical problems, while functioning as a reference for both experienced clinicians and trainees. It also includes relevant patient management protocols, as well as numerous emerging topics that are lacking in presently available texts.A Quick Reference to Obstetric Anesthesia is meant for anyone seeking immediately accessible information to facilitate real-time care of pregnant patients. Its approachable yet comprehensive knowledge base will be appreciated by anesthesia professionals at every level.

  • A Comprehensive Guide for the Novice Researcher in Clinical Trials

    • 1 Edición
    • Miltiadis Lytras + 2 más
    • Inglés
    A Comprehensive Guide for Novice Researcher in Clinical Trials is a must-have resource for individuals embarking on the journey of clinical research. This book is tailored for beginners, offering a clear and structured introduction to the vital principles, methodologies, and skills required to design and conduct robust clinical trials. Spanning 13 chapters, it meticulously covers the entire clinical trial process, emphasizing Good Clinical Practice (GCP) standards. From foundational research concepts to advanced trial strategies, the guide empowers readers to confidently navigate the complexities of clinical trials and contribute meaningfully to the field of healthcare.In addition to its foundational content, the book addresses a variety of important topics, such as ethical considerations, regulatory compliance, and the development of trial protocols. It explores different trial designs, types of bias, and the historical evolution of clinical research. Practical sections on data management, monitoring, statistical analysis, and project management offer readers hands-on guidance for real-world application. Notably, the book includes a dedicated focus on regulatory affairs in Saudi Arabia, making it particularly valuable for health professionals in that region.

  • Natural Gums as a Sustainable Material for Food Packaging and Preservation

    • 1 Edición
    • Haroon Elrasheid Tahir + 3 más
    • Inglés
    Natural Gums as a Sustainable Material for Food Packaging and Preservation focuses on the characterization, functionality, mechanisms, and processing of natural gum-based packages and its application for food preservation and smart packaging. Sections cover characterization, functionality, formulation, health, and eco-innovations in natural gums followed by global research indicators of gum packages. Additional content explores the application of natural gum and gum-based techniques for the protection of foods, including an evaluation of the potential use of gum-based smart packaging for the detection of food quality and safety in addition to the consumer acceptability of gum packaging.Final content focuses on natural gum package challenges, safety, and associated legislation followed by assessing the future potential of natural gum food packages. Edited by a team of experts in natural gums and food packaging materials, this book prioritizes sustainability and biodegradability by utilizing natural gums as an eco-friendly alternative to protect and indicate the freshness of foods.

  • Encyclopedia of Cardiovascular Research and Medicine

    • 2 Edición
    • Vasan Ramachandran S. + 1 más
    • Inglés
    Now in its second edition, the Encyclopedia of Cardiovascular Research and Medicine is a four‑volume print and online reference that brings together the essential knowledge needed to understand the heart and vascular system. Designed for students, clinicians, researchers, and instructors, it offers clear, authoritative coverage of how the cardiovascular system develops, functions, becomes injured, and can be repaired. Because cardiovascular disease remains the world’s leading cause of death, this edition provides the up‑to‑date scientific and clinical insights needed to support research, inform care, and improve outcomes.This revised edition includes around 180 expert articles spanning cardiac development and regeneration, vascular biology, genetics and omics technologies, coronary and acute cardiac syndromes, heart failure, electrophysiology and device therapies, imaging, population health, and modern research methods. By spanning basic, clinical, and population sciences, the encyclopedia supports a wide range of users from those seeking introductory knowledge to specialists pursuing advanced expertise in cardiovascular medicine.

  • Cholinergic Drugs for Alzheimer's Disease

    From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions
    • 1 Edición
    • Cheorl-Ho Kim
    • Inglés
    Cholinergic Drugs for Alzheimer’s Disease: From Central Cholinergic Neurotransmission to Drug Therapies and Natural Products with Multitarget Actions addresses the urgent need for advanced resources in neuropharmacology. The first section presents mechanistic insights into cholinergic drugs, current hypotheses for Alzheimer’s Disease progression, neurotransmitter systems, receptor biology, and the evolution of acetylcholinesterase inhibitors, including hybrid and multi-target drugs. It also covers clinical status, neuromuscular blockers, non-adrenergic neurotransmitters, protein kinase inhibitors, inflammation modulation, NMDA antagonism, biomarkers, and AI-assisted drug discovery.The second section explores natural alkaloidal and non-alkaloidal compounds, molecular docking, SAR analysis, and daily consumable resources, with the third section investigating marine-derived AChE inhibitors, dual- and multi-target drug concepts, and emerging therapeutic compounds. This book equips the scientific community with a robust foundation for understanding and innovating in Alzheimer’s Disease therapy. By integrating molecular biology, pharmacology, and computational approaches, it empowers researchers and clinicians to address treatment challenges, optimize drug design, and leverage natural products for multifactorial intervention.

  • Biofabrication and Synthetic Biology in Medicinal Plants

    Advances in Biotechnology and Breeding
    • 1 Edición
    • Eti Sharma + 2 más
    • Inglés
    Biofabrication and Synthetic Biology in Medicinal Plants: Advances in Biotechnology and Breeding presents recent technological advances for enhancing medicinal plants as sources of plant-based biopharmaceuticals. It covers biofabrication, synthetic biology, modern biotechnological tools, and innovative breeding strategies tailored for medicinal plant improvement. While these technologies are well established in crop plants, their application in medicinal plants remains underexplored. Medicinal plants are rich sources of therapeutic compounds traditionally used across cultures to treat a wide range of diseases and health conditions. These plants produce diverse bioactive molecules, including terpenoids, flavonoids, alkaloids, and phenolics, many of which exhibit significant pharmacological potential. For centuries, medicinal and aromatic plants have played a vital role in human healthcare and continue to be valued globally. Recent advances in synthetic biology, metabolic engineering, and biotechnology promise to enhance the production, quality, and efficacy of these bioactive compounds, addressing unmet medical needs and contributing to sustainable healthcare. This book compiles insights from leading experts, offering a comprehensive reference for researchers, early-career scientists, students, and professionals working in medicinal plant biotechnology and breeding.

  • Arginase: Structure, Function, and Therapeutic Targeting

    • 1 Edición
    • Volumen 740
    • Inglés
    Arginase: Structure, Function, and Therapeutic Targeting, Volume 740 in the Methods in Enzymology series, provides a comprehensive, methodology-driven perspective on arginase research spanning molecular, biochemical, and translational domains. Chapters in this new release include Expression, Purification, and Structural Characterization of Human and Leishmania Arginase with Comparative Analysis of Structures from the Protein Data Bank, Synthesis of First-Generation Arginase Inhibitors, Computational and Structure-Guided Design of Arginase Inhibitors, Metal Substitution in Arginase: Experimental Approaches to Study Metal-Dependent Catalysis, Therapeutic Arginase Formulations: PEGylation, Stability, and Advanced Delivery Systems, and much more.Additional chapters cover Dual ARG1/ARG2 Inhibition: Experimental and Structural Strategies for Inhibitor Design and Optimization, Synthesis of Second-Generation Arginase Inhibitors, Cryo-EM Workflow and Structural Characterization of Arginase–Antibody Complexes, Development and Validation of an Electrochemical Assay for Arginase Activity, Experimental and Structural Analysis of H. pylori Arginase in Gastric Immune Evasion, Agmatinase and Alternative Arginine Utilization Pathways in Bacteria: Biochemical and Functional Perspectives, Catalytic Diversification of the Arginase Fold: Structural and Mechanistic Insights from DcsB, Beyond Arginase: Structural Biology of the Extended Guanidinase Family, Plant Arginase: Structural and Functional Roles in Nitrogen Metabolism, and much more.

  • Lo esencial en farmacología. Cursos Crash

    • 6 Edición
    • Catrin Page
    • Español
    Con una fórmula que ha demostrado su éxito a lo largo de los últimos 25 años, cada volumen de la serie se ha actualizado por completo para facilitar el estudio. La serie está escrita por estudiantes de últimos cursos y recién graduados que acaban de superar sus exámenes, y toda la información ha sido cuidadosamente revisada por profesores universitarios. Este volumen de la serie se ha mejorado para satisfacer las necesidades de los estudiantes de Medicina actuales, y las de los estudiantes y profesionales de otras disciplinas sanitarias que requieran un acceso rápido a los aspectos esenciales de la farmacología. Cada capítulo guía de forma sucinta por todos los temas curriculares, integrando los aspectos clínicos con la ciencia básica relevante y evitando los detalles innecesarios o confusos. Los cuadros destacados a lo largo del texto ofrecen los apuntes, las sugerencias y los puntos clave esenciales. Se incluye una sección de autoevaluación totalmente revisada y adaptada a los últimos formatos de exámenes para comprobar los conocimientos y para ayudar en la preparación de las pruebas. Completamente revisada y actualizada, esta sexta edición ofrece un recurso accesible de aprendizaje y repaso que facilite la compresión de los principios y las aplicaciones de la farmacología en todas las áreas de la medicina y la cirugía. Comienza con un capítulo introductorio sobre los principios básicos de la farmacología. En el resto de los capítulos, se describen los efectos de los fármacos en los distintos sistemas orgánicos y se incluyen actualizaciones sobre los avances farmacológicos más recientes en medicina (p. ej., las nuevas terapias dirigidas en oncología y enfermedades inflamatorias, así como los nuevos tratamientos utilizados en el manejo de la diabetes y la insuficiencia cardíaca). La sección de autoevaluación se ha actualizado para reflejar el contenido y el estilo de varios exámenes de pre- y posgrado. Las preguntas de autoevaluación se centran en la farmacología clínica y su aplicación a casos reales de la práctica clínica.

  • Stem Cell-Mediated Regulation of Pyroptosis

    • 1 Edición
    • Debalina Bhattacharya + 1 más
    • Inglés
    Stem Cell-Mediated Regulation of Pyroptosis investigates the role of pyroptosis in various types of stem cells and stem cell-derived exosomes, considering how they can accelerate tissue repair and regeneration in inflammatory diseases. The book begins with an introduction to the mechanisms of pyroptosis and methods available for its detection. It then considers pyroptosis and its relationship to stem cells before delving into the interaction across various conditions, ranging from cerebral injury, spinal injury, cardiac injury, osteoarthritis, cancer, and more. Users will find the latest research and future directions in the study of stem cells and pyroptosis, thus enabling further understanding of the cellular mechanisms underlying this form of cell death and the clinical significance of stem cells in the context of pyroptosis-induced diseases. Therapeutic implications and potential strategies targeting this pathway for the treatment of such conditions are also considered, providing a comprehensive reference that will be useful to researchers working across cell biology, regenerative medicine, immunology, therapeutics, and other related fields.

  • Food and Consumer Behavior

    A Comprehensive Reference
    • 1 Edición
    • Herbert L. Meiselman
    • Inglés
    What and how we eat has big implications for our health, our society and the environment. Therefore, it is crucial that we understand what people eat, the reasons why people eat the way they do, and how we can best change food consumer practices. Food is the biggest business in the world, but until recently the emphasis has been on food science and technology (the food product) and not on the food consumer. But there has been a lot of progress in the past 10-20 years on consumer research for foods. There is currently no reference that pulls together these developments. Food and Consumer Behavior: A Comprehensive Reference will emphasise methods for studying consumer responses to foods. The book will also emphasise cross-cultural approaches to studying consumer food behaviour, with the goal of extending the field to all parts of the globe, including Asia and Africa.

  • Understanding the Functional, Flavor, and Nutritional Properties of Blue Foods

    • 1 Edición
    • Volumen 119
    • Inglés
    Understanding the Functional, Flavor, and Nutritional Properties of Blue Foods, Volume 119 provides a holistic and in-depth examination of blue foods, moving beyond basic nutrition to explore their multifaceted roles. Chapters in this new release include Red seaweed Palmaria palmata: A sustainable protein source for the future, Nutritional and Functional Bioactive Compounds in Fish, Fermented fish: A Deep Dive into Tradition, Innovation, ad Health Benefits, Phlorotannins from marine algae, Shrimp: Nutrition, Preservation and Processing, Nutritional , Flavor and Functional Properties of Golden Pomfret, Fish by-products: Functional properties, health attributes, and challenges, and much more.Additional chapters cover Exploring the Flavor Profiles of Blue Foods: Mechanistic Insights, Factor Analysis, and Assessment Strategies, and Non-thermal processing of fish: Evolution of flavor, physico-chemical properties, and bioactivities. By integrating perspectives from food science, nutrition, gastronomy, and sustainability, this volume positions blue foods as essential components of future food systems, offering scientific insights for their valorization and innovative application.

  • Retina Structure, Function, and Genetics

    • 1 Edición
    • Volumen 217
    • Machelle T. Pardue
    • Inglés
    Retina Structure, Function, and Genetics focuses on recent research on the ocular structure responsible for visual function. Introductory chapters cover epidemiology and genetics of the retina, while structural chapters cover development, anatomy, the fovea, retinal cell types, and vasculature. Additional content covers neurotransmitters and circuits, phototransduction, ganglion cell physiology, higher order visual processing, and color and spatial vision.

  • Técnicas en histología y biología celular

    • 3 Edición
    • Luis Montuenga Badía + 2 más
    • Español
    Esta nueva edición de Técnicas en histología y biología celular, completamente actualizada, desarrolla de modo asequible los fundamentos teóricos y metodológicos de las técnicas más relevantes en histología y biología celular, incluyendo aquellas técnicas de biología molecular relacionadas con ambas disciplinas. Presenta los fundamentos de las diversas metodologías a estudiantes del ámbito de las ciencias biológicas, la bioquímica y la biomedicina, así como a técnicos de anatomía patológica y otros profesionales biosanitarios que deseen conocer estas técnicas con un abordaje avanzado. Asimismo, proporciona a los investigadores, técnicos o clínicos que se inician en el campo del laboratorio o la investigación biológica y biomédica la información necesaria para introducirse con seguridad en el ámbito del análisis microscópico y la biología celular, incluidas sus bases moleculares. Incluye capítulos sobre procesamiento y tinción de las muestras; inmunolocalización; hibridación in situ de ácidos nucleicos; cultivo de tejidos; técnicas multiómicas; microscopía confocal, electrónica y de fuerza atómica; análisis de imagen; ingeniería tisular, etc. Así mismo, la nueva edición presenta numerosas imágenes originales y esquemas que ilustran los conceptos básicos y muestran ejemplos prácticos del uso de las diversas técnicas. Ofrece acceso a la versión digital del libro a travésde https://online.vital... con nuevos recursos didácticos asociados a cada uno de los temas, incluyendo actividades y casos prácticos, preguntas de autoevaluación, imágenes complementarias, bibliografía adicional y enlaces de interés.

  • Applied Advanced Technologies in Marine Fish Aquaculture

    • 1 Edición
    • Daniel Benetti
    • Inglés
    Applied Advanced Technologies in Marine Fish Aquaculture provides detailed overviews on the most advanced technologies for full-cycle production of marine fish, from hatchery to market. The book describes original technical protocols that were improved over the years to assist the reader in all stages of aquaculture projects development, from inception to operation, at both research and commercial scales.Professor Daniel Benetti conveys here all his extensive and successful experience working with dozens of commercially important marine fish species in several countries throughout the world. He addresses all basic and applied aspects of marine fish aquaculture, presenting the most advanced methods and protocols for all stages of the production cycle, from broodstock reproduction and management to spawning, larval rearing and early developmental stages including nursery and growout methods.Applied Advanced Technologies in Marine Fish Aquaculture is innovative as it takes a practical, applied approach of merging science and technology of tropical and subtropical marine fish aquaculture into a state-of-the-art compendium with detailed guidelines that will serve as seminal reference for students, researchers, managers, investors, consultants, government officers and other professionals working in the field worldwide

  • Applications in Microwave Processing

    Expanding the Scope beyond Cooking, Benefits, and Risks
    • 1 Edición
    • Olalere Olusegun Abayomi + 5 más
    • Inglés
    Applications in Microwave Processing: Expanding the Scope beyond Cooking, Benefits and Risks provides a comprehensive guide on the principles and recent interest in microwave technology, along with its cross-disciplinary applications. Divided into two sections, the first one discusses the foundation of the principle, emerging applications, and recent interest in microwave technology. The second section explores the cross-discipline applications of microwave technology in different fields, which include bioactive extraction, clinical thermo-therapy, polymer processing, catalytic pyrolysis, thermal sterilization, biopharmaceuticals, wastewater treatment, drying process, mineral processing, and in biological process.Overall, this title discusses the drawback of microwave assisted technology, scalability concerns and outlook. Edited by a team of experts in the field, this book is a great asset for all researchers, Industrial expert, Biotechnologist and all interested in optimal management and usage of microwaves.

  • Advances in Marine Biology

    • 1 Edición
    • Volumen 103
    • Inglés
    Advances in Marine Biology, Volume 103, the latest release in this serial that highlights new advances in the field, includes comprehensive chapters written by an international board of authors.

  • Comprehensive Review of Lower Genital Neoplasms

    With Case Discussion
    • 1 Edición
    • Nadereh Behtash + 3 más
    • Inglés
    Comprehensive Review of Lower Genital Neoplasms: With Case Discussion offers a practical, case-based guide to diagnosing and managing human papillomavirus (HPV)-related genital diseases. Designed for healthcare professionals, this resource simplifies complex concepts through engaging case presentations and high-quality colposcopy images, enhancing both visual learning and clinical skills.Comprehensive Review of Lower Genital Neoplasms: With Case Discussion offers a practical, case-based guide to diagnosing and managing human papillomavirus (HPV)-related genital diseases. Designed for healthcare professionals, this resource simplifies complex concepts through engaging case presentations and high-quality colposcopy images, enhancing both visual learning and clinical skills.This book bridges gaps in existing literature by combining evidence-based knowledge with hands-on teaching strategies, making it essential for clinicians to advance their expertise in HPV-related conditions.

  • Capsaicin, the Pungent Principle in Hot Pepper

    From Basic Pharmacology to Therapeutic Applications
    • 1 Edición
    • Arpad Szallasi
    • Inglés
    Capsaicin, the Pungent Principle in Hot Pepper: From Basic Pharmacology to Therapeutic Applications explores capsaicin's biological and pharmacological characteristics, from its discovery and isolation to its receptor identification and antagonists. The book's structure is divided into three sections, starting with the historical development of research on capsaicin. This foundational section provides a thorough understanding of the compound's journey from a simple pungent ingredient to a significant element in pharmacological studies. The second part of the book delves into capsaicin’s biological effects and pharmacology, covering areas such as nociception, pain, salivary secretion, body temperature regulation, and blood pressure regulation.Finally, the book examines the clinical applications of capsaicin, discussing potential future developments in desensitization, pain relief, injections, effects on the tumor microenvironment, appetite control, and longevity. This book is invaluable for pharmacology researchers and clinicians in pain management and cancer, offering insights into the unique characteristics and therapeutic potential of capsaicin.

  • Emerging Trends in Cancer Research

    • 1 Edición
    • Ranjita Shegokar + 1 más
    • Inglés
    Emerging Trends in Cancer Research provides a comprehensive and up-to-date exploration of the latest advancements in cancer therapeutics, diagnostics, and intellectual property landscapes. Each chapter delves into the specific aspects of different cancers, offering insights into drug resistance mutations, biomarker trends, preclinical model updates, and clinical pipeline developments. The book also addresses the importance of diagnostics and the evolving landscape of intellectual property in cancer treatment. Sections analyze cancer drug resistance mutations, biomarker trends, and diagnostics across various cancers, including intestinal, cardiac, brain, and blood cancers.Readers will find coverage of clinical pipeline developments, intellectual property landscapes, and advancements in cancer therapeutics, diagnostics, and global drug delivery trends. This book is an invaluable resource for oncology, biomedical engineering, and pharmaceutical professionals, offering insights into the latest cancer research trends. It includes real-world case studies, practical applications, and discussions on regulatory and ethical considerations, making it essential for both seasoned researchers and graduate students.

  • Seldin and Giebisch's The Kidney

    Physiology and Pathophysiology
    • 6 Edición
    • Robert J. Alpern + 3 más
    • Inglés
    Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, Sixth Edition provides a common language for nephrology researchers, fellows, and practicing nephrologists to discuss normal and abnormal renal physiology and the development and diagnosis of a wide range of renal diseases. Guided by a team of four distinguished authorities in nephrology, experts from all areas of renal research and practice take readers from the structure and function of the normal kidney, to the specific cellular and molecular mechanisms underlying disease development, and into the management of renal disease through physiologic regulation. This classic nephrology reference for nearly 30 years combines basic and clinical sciences that provides authoritative, concise, and readily accessible information. Academic, medical, and pharma researchers save valuable time by quickly accessing the very latest details on renal physiology and pathophysiology as opposed to searching through thousands of journal articles.

  • Molecular Mechanisms of Spermatogenesis

    • 1 Edición
    • Volumen 168
    • Inglés
    Molecular Mechanisms of Spermatogenesis, Volume 168 provides a comprehensive overview of the molecular mechanisms that govern spermatogenesis, the complex process through which sperm cells are produced in the male testes. Sections in this new release include: From undifferentiated gonads to ovaries and testes, Molecular regulation of germ-somatic cell interactions: insights from spatial transcriptomics, All about the mammalian germline cyst, Stem cell competition, Genetic and epigenetic regulation of cell fate determination of human spermatogonial stem cells, A Sertoli Valve niche at the Terminal End of Seminiferous Tubules for Mammalian Spermatogenic Stem Cells, The formation and function of the synaptonemal complex, and more.Additional sections cover Meiotic crossover control: interplay between the recombination process and chromosome organization, Drosophila spermiogenesis, New Insights on the Biogenesis and Functional Importance of the Sperm Cytoplasmic Droplet, Asymmetric male meiosis in genetics and evolution, Current understanding of adult stem cells in Leydig cell biology, Unraveling the complexity of spermatogenesis from single-cell perspective, and much more.

  • Chalcones

    From Drug Discovery to Pharmaceutical Applications
    • 1 Edición
    • Simone Carradori + 2 más
    • Inglés
    Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

  • Ion Channels in Cellular Pathophysiology Part A

    • 1 Edición
    • Volumen 97
    • Inglés
    Ion Channels in Cellular Pathophysiology, Part A, Volume 97 in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Possible therapeutic effects of essential oils on Na channels in experimental diabetic neuropathy, Modulation of ion channels by Group I metabotropic glutamate receptors, ATP-sensitive potassium channels in neurons: roles in and beyond metabolic control, Chemically induced cardiotoxicity: role of voltage dependent ion channels, Thyroid Hormone Deficiency-Induced Cardiac Ion Channel Dysfunction: Molecular Mechanisms and Arrhythmic Implications, and much more.Additional chapters discuss Pathophysiological Insights into Ion Channel Dysregulation and Electrical Remodeling in Cardiac Cells During Trypanosoma cruzi Infection, Targeting Sodium Channels in Neuroblastoma: Implications for Cellular Physiology, Breast cancer and voltage ion channels, Alpha-helical charged peptides a new concept of NaV gating modifiers, Nerve electrophysiological alterations in experimental diabetic neuropathy, and Cardioprotective effect of natural products on doxorubicin-induced acute cardiotoxicity and cardiac ischemia-reperfusion injury.

  • Computer-Aided Drug Design in Modern Drug Discovery

    • 1 Edición
    • Yinuo Wu + 2 más
    • Inglés
    Computer-Aided Drug Design in Modern Drug Discovery offers an in-depth exploration of CADD, featuring real-world case studies and practical examples that empower researchers to effectively harness this technology in drug discovery and development. Exploring the intricacies of CADD, the book comprises several key chapters, beginning with an introduction to its methods and evolution that is followed by a thorough examination of the integration of artificial intelligence in drug design. Subsequent chapters cover various CADD approaches, including ligand-based, structure-based, and fragment-based design, alongside AI-driven compound generation and drug screening.The book also showcases a selection of marketed drugs developed with CADD or AI, such as Captopril, Tirofiban, and Crizotinib, providing invaluable insights into the successes and challenges faced in real-world applications. Finally, the discussion of emerging trends and future directions in CADD and AI highlights the ongoing evolution of these methodologies and their integration with traditional drug development processes.

  • Advancing Biotechnology and Environmental Science Through Sustainable Innovations in Green Chemistry

    • 1 Edición
    • Volumen 20
    • Usama Afzal + 2 más
    • Inglés
    Advancing Biotechnology and Environmental Science Through Sustainable Innovations in Green Chemistry explores the transformative potential of green chemistry in addressing critical challenges in healthcare and environmental fields. The book provides a comprehensive guide on integrating sustainable innovations into various industries, promoting resource-saving processes and reducing waste to enhance environmental sustainability. With a strong focus on practical applications, the book delves into the development of environmentally-frie... materials and technologies, such as biodegradable polymers and advanced nanostructures. It highlights how these innovations can significantly improve environmental and health outcomes through detailed case studies and real-world examples.Sections cover medical, environmental applications, and environmental science. Each chapter includes visual elements like flowcharts, step-by-step procedures, and comparison tables, thus enhancing accessibility and retention of information. This book is an invaluable resource for scientists, researchers, and practitioners in chemistry, medicine, and environmental science.

  • Designer Crops

    Implications of Artificial Intelligence and Modern Biotechnological Methods
    • 1 Edición
    • Santosh Kumar Upadhyay
    • Inglés
    Designer Crops: Implications of Artificial Intelligence and Modern Biotechnological Methods explores the global impact of environmental challenges and climate change on crop productivity. This comprehensive guide reveals how abiotic and biotic stresses and shifting climatic conditions have significantly affected traditional cropping systems and crop yields worldwide. This book discusses designer crops and climate-resilient and super cropping systems by applying diverse information from biotechnology, crop breeding, machine learning, and automation in agriculture. It showcases the evolution of technologies such as high-throughput genome sequencing, artificial intelligence, and precision breeding, revolutionizing crop design for enhanced disease resistance, nutritional value, and increased yields.In addition, it examines modern biotechnological tools and speed breeding strategies, offering a glimpse into the promising future of super crop development. Contributions from leading global experts on artificial intelligence in agriculture, machine learning for smart agricultural practices, and climate-resilient cropping strategies make this book a must have for upper-level undergraduate students in the fields of crop science, biotechnology, and sustainable agriculture. It will also be useful for researchers and professionals working in food technology, agricultural automation, and environmental consulting.

  • Updates in Adrenal Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 55-2
    • Smita B. Abraham
    • Inglés
    In this issue of Endocrinology and Metabolism Clinics, guest editor Dr. Smita B. Abraham brings her considerable expertise to the topic of Updates in Adrenal Disorders. Top experts discuss the latest developments in diagnosis and management of adrenal disorders, including topics such as diagnosis and management of adrenocortical carcinoma; management of adrenal tumors in pregnancy; autonomous cortisol secretion; primary bilateral macronodular adrenal hyperplasia; evaluation and management of primary hyperaldosteronism; and more.

  • Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment

    • 1 Edición
    • Volumen 169
    • Inglés
    Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment, Volume 169 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include an Introduction to Nanotechnology in Dermatology, Basics of Skin Cancer: Types, Diagnosis, and Current Challenges, Current Challenges in Skin Cancer Diagnosis and Treatment, Nanocarriers for Drug Delivery in Skin Cancer, Nanotechnology in Skin Cancer Diagnosis, Therapeutic Nanoparticles and Targeted Therapy, and much more.Additional chapters cover Nanotechnology in Photodynamic and Photothermal Therapy for Skin Cancer, Challenges in Translating Nanotechnology from Research to Clinical Practice, Nanotechnology and Immunotherapy Synergies in Skin Cancer, Patient-Centric Approaches and Personalized Nanomedicine in Skin Cancer, The Role of Theranostics and Nanotheranostics in Skin Cancer Management, Preclinical and Clinical Trials in Nanotech Skin Cancer Treatment, Safety, Ethical, and Regulatory Considerations in Nanotechnology for Skin Cancer, and many more interesting chapters on topics of current interest.

  • The Microbiome and Cancer Treatment

    Overcoming Resistance and Enhancing Efficacy
    • 1 Edición
    • Sadhna Aggarwal + 3 más
    • Inglés
    The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The book's chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance.Sect... also address the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters foster interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. Readers will benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.

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