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Elsevier

Libros en Ciencias de la Vida

  • Microfluidics in Cell Biology: Part A: Microfluidics for Multicellular Systems

    • 1 Edición
    • Volumen 146
    • Inglés
    Microfluidics in Cell Biology Part A: Volume 146, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections on Cell monolayers/spheroids... Collective migration in microtubes, Leukocyte adhesion dynamics on endothelial monolayers under flow, Constrained spheroid for perfusion culture, Cells in droplet arrays, Heart on chips, Kidney on chips, Liver on chips and hepatic immune responses, Gut on chips, 3D microvascular model-based lymphoma model, Blood brain barrier on chips, Multi-organ-on-a-chi... for pharmacokinetic analysis, Cancer immunotherapy on chips, and more.

  • Emergent Neuroimaging: A Patient Focused Approach, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 28-3
    • Diego B. Nunez
    • Inglés
    This issue of Neuroimaging Clinics of North America focuses on Emergent Neuroimaging: A Patient Focused Approach, and is edited by Dr. Diego B. Nunez. Articles will include: The adult patient with acute neurologic deficit: an update on imaging trends; The patient with thunderclap headache; Imaging considerations in the patient with intracerebral hemorrhage; Emergent neuroimaging in the oncologic and immunosuppressed patient; Emergent neuroimaging during pregnancy and puerperium; Imaging the unconscious “found down” patient in the ED; Neurological emergencies in the pediatric patient including accidental and non-accidental trauma; Head and neck injuries: special considerations in the elderly patient; Current challenges in the use of CT and MRI in suspected cervical spine trauma; Radiation considerations in emergent neuroimaging; Blunt cranio-cervical trauma: Does the patient have a cerebral vascular injury?; New and emerging patient-centered CT imaging and image-guided treatment paradigms for maxillofacial trauma; Acute neurological syndromes beyond stroke: The role of emergent MRI; and more!

  • The Immune System and Mental Health

    • 1 Edición
    • Hymie Anisman + 2 más
    • Inglés
    The Immune System and Mental Health fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. Sociology, psychology, psychiatry, neuroscience and genetics have provided considerable explanations and solutions to some of the most intractable mental-health problems. But researchers are increasingly relying on investigations of the immune system to identify factors that can undermine and impair mental health. This book covers devastating mental-health conditions, such as depression, anxiety, schizophrenia, and autism-like spectrum disorders. In addition, degenerative disorders of the brain, such as Parkinson’s and Alzheimer’s-like dementia are explored.

  • Management of High Altitude Pathophysiology

    • 1 Edición
    • Kshipra Misra + 2 más
    • Inglés
    Management of High Altitude Pathophysiology presents a comprehensive overview on the various therapeutic practices and ongoing research relating to the development of more potent and novel formulations for managing high altitude pathophysiology. It provides a detailed application of both herbal and non-herbal therapeutic agents, including their nanoformulations. This important reference provides benefits to the medical and herbal scientific communities, doctors treating patients with high altitude complications, individuals travelling to high altitudes for recreation or work, and scientists working on future drug development.

  • Dehydroepiandrosterone

    • 1 Edición
    • Volumen 108
    • Gerald Litwack
    • Inglés
    Dehydroepiandrostero... Volume 108, the latest release in the Vitamins and Hormones series first published in 1943, covers the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms, with this release focusing on topics such as Dehydroepiandrostero... Research: Past, Current and Future, Astrocyte Neuroprotection and Dehydroepiandrostero... Mutation of HSD3B2 Gene and Fate of Dehydroepiandrostero... Autophagy and Autophagic Cell Death: Uncovering New Mechanisms Whereby Dehydroepiandrostero... Promotes Beneficial Effects on Human Health, Dehydroepiandrostero... and Cardiovascular Disease, Dehydroepiandrostero... and Experimental Osteoarthritis, The Role of Dehydroepiandrostero... (DHEA) in Skeletal Muscle, Mechanism of Action of Dehydroepiandrostero... and more.

  • Current Trends and Future Developments on (Bio-) Membranes

    Carbon Dioxide Separation/Capture by Using Membranes
    • 1 Edición
    • Angelo Basile + 1 más
    • Inglés
    Current Trends and Future Developments on (Bio-) Membranes: Carbon Dioxide Separation/Capture by Using Membranes explores the unique property of membranes to separate gases with different physical and chemical properties. The book covers both polymeric and inorganic materials for CO2 separation and explains their mechanism of action, allowing for the development and most appropriate and efficient processes. It also lists the advantages of using membranes instead of other separation techniques, i.e., their low operating costs and low energy consumption. This book offers a unique opportunity for scientists working in the field of membrane technology for CO2 separation and capture.

  • The Value of BCG and TNF in Autoimmunity

    • 2 Edición
    • Denise Faustman
    • Inglés
    The Value of BCG and TNF in Autoimmune Diseases, Second Edition provides an overview on the current research related to TNF induction and the use of the BCG vaccine as a potential treatment approach to diverse forms of autoimmunity, allergies, infections and neurologic diseases. Since the initial conference (2013) and first edition of this book (2014), the field of BCG research has grown considerably. This new edition contains updates on MS and diabetes, and features at least eight additional chapters on new prevention and treatment trials in autoimmunity and allergy, along with a new understanding of the genetics of BCGs.

  • Integrated Analytical Approaches for Pesticide Management

    • 1 Edición
    • Britt Maestroni + 1 más
    • Inglés
    Integrated Analytical Approaches for Pesticide Management provides proven laboratory practices/examples and methods necessary to control pesticides in food and water in various environments. The book presents insights into good laboratory practices and examples of methods used in individual specialist laboratories, thus enabling stakeholders in the agri-food industry to appreciate the importance of proven, reliable data and the associated quality assurance approaches for end product testing for toxic levels of contaminant residues in food. The book is written in a rigorous, but simple, way to make sure that a broad range of readers can appreciate its technical content. The book's practical nature and generic guidelines distinguish it from others in the marketplace.

  • Transformative Paleobotany

    Papers to Commemorate the Life and Legacy of Thomas N. Taylor
    • 1 Edición
    • Michael Krings + 3 más
    • Inglés
    Transformative Paleobotany: Papers to Commemorate the Life and Legacy of Thomas N. Taylor features the broadest possible spectrum of topics analyzing the structure, function and evolution of fossil plants, microorganisms, and organismal interactions in fossil ecosystems (e.g., plant paleobiography, paleoecology, early evolution of land plants, fossil fungi and microbial interactions with plants, systematics and phylogeny of major plant and fungal lineages, biostratigraphy, evolution of organismal interactions, ultrastructure, Antarctic paleobotany). The book includes the latest research from top scientists who have made transformative contributions. Sections are richly illustrated, well concepted, and characterize and summarize the most up-to-date understanding of this respective and important field of study.

  • Advances in Marine Biology

    • 1 Edición
    • Volumen 79
    • Inglés
    Advances in Marine Biology, Volume 79, the latest release in a series that has been providing in-depth and up-to-date reviews on all aspects of marine biology since 1963, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. This latest release includes a review of patterns of multiple paternity across sea turtle rookeries, parasites and pathogens in seabirds, progress in marine genomics and bioinformatics, the rise of sea turtle research and conservation, and the potential impacts of offshore oil and gas activities on deep-sea sponges and the habitats they form.

  • Reproductomics

    The -Omics Revolution and Its Impact on Human Reproductive Medicine
    • 1 Edición
    • José A. Horcajadas + 1 más
    • Inglés
    Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.

  • Biscuit, Cookie and Cracker Production

    Process, Production and Packaging Equipment
    • 1 Edición
    • Iain Davidson
    • Inglés
    Biscuit, Cookie, and Cracker Production: Process, Production, and Packaging Equipment is a practical reference that brings a complete description of the process and equipment necessary for automated food production in the food/biscuit industry. The book describes the existing and emerging technologies in biscuit making and production, bringing a valuable asset to R&D personnel and students in food technology and engineering areas. Full of clear illustrations, photos and text describing types of biscuits, cookies and crackers, ingredients, test bakery equipment, dough piece forming, biscuit baking ovens, biscuit cooling and handling, and processing and packaging, this book presents a timely resource on the topic.

  • Coronary Microvascular Obstruction in Acute Myocardial Infarction

    From Mechanisms to Treatment
    • 1 Edición
    • Giampaolo Niccoli + 1 más
    • Inglés
    Coronary Microvascular Obstruction in Acute Myocardial Infarction: From Mechanisms to Treatment provides a comprehensive understanding of the phenomenon of coronary microvascular obstruction (CMVO) that is the main limitation of reperfusion therapies in ST-elevation myocardial infarction. It provides in-depth coverage of the phenomenon of CMVO which heavily affects prognosis by increasing the risk of death and heart failure at follow-up. A first of its kind reference dedicated solely to this topic, it is appropriate for a wide audience, from researchers, to those who aid in the management, prevention and treatment of CMVO.

  • Plasma Medical Science

    • 1 Edición
    • Shinya Toyokuni + 3 más
    • Inglés
    Plasma Medical Science describes the progress that has been made in the field over the past five years, illustrating what readers must know to be successful. As non-thermal, atmospheric pressure plasma has been applied for a wide variety of medical fields, including wound healing, blood coagulation, and cancer therapy, this book is a timely resource on the topics discussed.

  • Pediatric Food Preferences and Eating Behaviors

    • 1 Edición
    • Julie C. Lumeng + 1 más
    • Inglés
    Pediatric Food Preferences and Eating Behaviors reviews scientific works that investigate why children eat the way they do and whether eating behaviors are modifiable. The book begins with an introduction and historical perspective, and then delves into the development of flavor preferences, the role of repeated exposure and other types of learning, the effects of modeling eating behavior, picky eating, food neophobia, and food selectivity. Other sections discuss appetite regulation, the role of reward pathways, genetic contributions to eating behaviors, environmental influences, cognitive aspects, the development of loss of control eating, and food cognitions and nutrition knowledge. Written by leading researchers in the field, each chapter presents basic concepts and definitions, methodological issues pertaining to measurement, and the current state of scientific knowledge as well as directions for future research.

  • 3D Printing Applications in Cardiovascular Medicine

    • 1 Edición
    • James K Min + 3 más
    • Inglés
    3D Printing Applications in Cardiovascular Medicine addresses the rapidly growing field of additive fabrication within the medical field, in particular, focusing on cardiovascular medicine. To date, 3D printing of hearts and vascular systems has been largely reserved to anatomic reconstruction with no additional functionalities. However, 3D printing allows for functional, physiologic and bio-engineering of products to enhance diagnosis and treatment of cardiovascular disease. This book contains the state-of-the-art technologies and studies that demonstrate the utility of 3D printing for these purposes.

  • Health Data Processing

    Systemic Approaches
    • 1 Edición
    • Marius Fieschi
    • Inglés
    Health Data Processing: Systemic Approaches focuses on the design of health information systems and touches on the main themes of medical informatics and public health. The book is written for health professionals in practice or training, and is especially useful for decision-makers or future decision-makers in the field of health information systems. Users will find sections on the question of reusing data for other purposes, protection of individual liberties that this data and technologies make more acute, and the irruption of large masses of genetic data and its related problems. This book develops the methodological and conceptual aspects related to these issues.

  • Safety Risk Management for Medical Devices

    • 1 Edición
    • Bijan Elahi
    • Inglés
    Safety Risk Management for Medical Devices demystifies risk management, providing clarity of thought and confidence to the practitioners of risk management as they do their work. Written with practicing engineers, safety management professionals, and students in mind, this book will help readers tackle the difficult questions, such as how to define risk acceptance criteria and how to determine when to stop risk reduction. This book delivers not only theory, but also practical guidance for applying the theory in daily risk management work. The reader is familiarized with the vocabulary of risk management and guided through a process to ensure compliance with the international standard ISO 14971—a requirement for all medical devices. This book outlines sensible, easily comprehensible, and state-of the-art methodologies that are rooted in current industry best practices. Opening chapters introduce the concept of risk, the legal basis for risk management, and the requirements for a compliant risk-management process. The next group of chapters discusses the connection between risk management and quality systems, usability engineering and biocompatibility. This book delves into the techniques of risk management, such as fault tree analysis and failure modes and effects analysis, and continues with risk estimation, risk control, and risk evaluation. Special topics such as software risk management, clinical investigations, and security are also discussed. The latter chapters address benefit-risk analysis, and production and postproduction monitoring. This book concludes with advice and wisdom for sensible, efficient, and successful safety risk management of medical devices.

  • Microalgae in Health and Disease Prevention

    • 1 Edición
    • Ira Levine + 1 más
    • Inglés
    Microalgae in Health and Disease Prevention is a comprehensive reference that addresses the historical and potential use of microalgae, its extracts, secondary metabolites, and molecular constituents for enhancing human health and preventing diseases. Each chapter features an overview, and the book includes coverage of microalgae biology, harmful algae, the use of microalgae in alcohol and food, and as sources of macronutrients, micronutrients, vitamins, and minerals. The historical use of microalgae, in addition to its potential use as a nutraceutical and cosmeceutical, is also addressed. The book provides coverage of relevant, up-to-date research as assembled by a group of contributors who are dedicated to the advancement of microalgae use in health, diet and nutrition.

  • Encyclopedia of Reproduction

    • 2 Edición
    • Michael K. Skinner
    • Inglés
    Encyclopedia of Reproduction, Second Edition, Six Volume Set comprehensively reviews biology and abnormalities, also covering the most common diseases in humans, such as prostate and breast cancer, as well as normal developmental biology, including embryogenesis, gestation, birth and puberty. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers, from advanced undergraduate students, to research professionals. Chapters also explore the latest advances in cloning, stem cells, endocrinology, clinical reproductive medicine and genomics. As reproductive health is a fundamental component of an individual’s overall health status and a central determinant of quality of life, this book provides the most extensive and authoritative reference within the field.

  • New Concepts in the Management of Septic Perianal Conditions

    • 1 Edición
    • Riyadh Mohammad Hasan + 1 más
    • Inglés
    New Concepts in the Management of Septic Perianal Conditions provides a comprehensive review of the medically important basic and clinical aspects of perianal diseases in adults. This book presents current, medically important information in the rapidly changing field of anorectal diseases, including significant topics like perianal abscess and fistula. It provides an accurate source of clinically relevant information that is presented clearly and succinctly, making it perfect for the diagnosis, treatment and management of septic perianal conditions.

  • Mitosis and Meiosis Part B

    • 1 Edición
    • Volumen 145
    • Inglés
    Mitosis and Meiosis, Part B, Volume 145, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are chapters on Mitotic live cell imaging at different time scales, the characterization of mitotic spindle by multi-mode correlative microscopy, STED microscopy of mitosis, Correlating light microscopy with serial block face scanning electron microscopy to study mitotic spindle architecture, quantification of three-dimensional spindle architecture, Imaging based assays for mitotic chromosome condensation and dynamics, and more.

  • Cancer Nanotechnology

    • 1 Edición
    • Volumen 139
    • Inglés
    Advances in Cancer Research, Volume 139, provides invaluable information on the exciting and fast-moving field of cancer research. Original reviews are presented on a variety of topics relating to the rapidly developing intersection between nanotechnology and cancer research, with unique sections in the new release focusing on Exosomes as a theranostic for lung cancer, Nanotechnology and cancer immunotherapy, Ultrasound imaging agents and delivery systems, Dendronized systems for the delivery of chemotherapeutics, Thermosensitive liposomes for image-guided drug delivery, Supramolecular Chemistry in Tumor Analysis and Drug Delivery, Gold nanoparticles for delivery of cancer therapeutics, and Single cell barcode microchip for cancer research and therapy.

  • Atlas of Hematopathology

    Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches
    • 2 Edición
    • Faramarz Naeim + 3 más
    • Inglés
    Atlas of Hematopathology: Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches, Second Edition, will appeal to both a wide range of people undergoing training in a variety of medical fields and practicing non-hematopathologis... For clinicians, fellows and residents, correct diagnosis (and therefore correct treatment) of diseases depends on a strong understanding of the molecular basis for the disease, making this book a crucial resource. This atlas contains hundreds of high-quality color images that mirror the findings that fellows and clinicians encounter in practice. In addition, it provides information in a quick, simple and user-friendly manner, attracting both those in training and non- experts. Residents, fellows, practicing clinicians, and researchers in pathology, hematology and hematology/oncology will find this a useful resource.

  • Epigenetics and Psychiatric Disease

    • 1 Edición
    • Volumen 157
    • Inglés
    Epigenetics and Psychiatric Disease, Volume 157, the latest volume in the Progress in Molecular Biology and Translational Science series, includes recent developments on a variety of topics, including the Epigenetic landscapes of the adversity-exposed brain, Chromosomal conformations and epigenomic regulation in schizophrenia, Progress in the epigenetics of depression, the epigenetics of circadian rhythms in imprinted neurodevelopmental disorders, DNA methylation mediating substance abuse, mechanisms and therapeutic opportunities, DNA methylation in animals model of psychosis, Epigenetics of early life stress, Epigenetic drugs for mood disorders, and more.

  • The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World

    • 1 Edición
    • Donald W. Duszynski + 2 más
    • Inglés
    The fundamental concept of The Biology and Identification of the Coccidia (Apicomplexa) of Carnivores of the World is to provide an up-to-date reference guide to the identification, taxonomy, and known biology of apicomplexan intestinal and tissue parasites of carnivores including, but not limited to, geographic distribution, prevalence, sporulation, prepatent and patent periods, site(s) of infection in the definitive and (if known) intermediate hosts, endogenous development, cross-transmission, pathology, phylogeny, and (if known) their treatments. These data will allow easy parasite recognition with a summation of virtually everything now known about the biology of each parasite species covered. The last (very modest) and only treatise published on this subject was in 1981 so this book fills a fundamental gap in our knowledge of what is now known, and what is not, about the coccidian parasites that infect and sometimes kill carnivores and/or their prey that can harbor intermediate stages, including many domestic and game animals.

  • Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders

    • 1 Edición
    • Elizabeth B. Torres
    • Inglés
    Objective Biometric Methods for the Diagnosis and Treatment of Nervous System Disorders provides a new and unifying methodological framework, introducing new objective biometrics to characterize patterns of sensory motor control underlying symptoms. Its goal is to radically transform the ways in which disorders of the nervous system are currently diagnosed, tracked, researched and treated. This book introduces new ways to bring the laboratory to the clinical setting, to schools and to settings of occupational and physical therapy. Ready-to-use, graphic user interfaces are introduced to provide outcome measures from wearable sensors that automatically assess in near real time the effectiveness of interventions. Lastly, examples of how the new framework has been effectively utilized in the context of clinical trials are provided.

  • Analytical Methods for Food Safety by Mass Spectrometry

    Volume I Pesticides
    • 1 Edición
    • Guo-Fang Pang
    • Inglés
    Analytical Methods for Food Safety by Mass Spectrometry, Volume One: Pesticides systematically introduces the Pesticide and Veterinary Drug Multiresidues Analytical Methods. Volume One includes discussions on 20 pesticide multiresidues chromatic-MS (GC-MS and LC-MS/MS) analytical techniques that have the capability of detecting over 800 pesticides and chemicals in 10 categories of agricultural products, including fruits, vegetables, grains, teas, Chinese medicinal herbs, edible fungus mushrooms, fruit and vegetable juices, animal tissues, aquatic products, raw milk and milk powders, and drinkable water. This book also includes chromatic-MS analytical parameters, linear equations and GPC chromatic behavior parameters for over 800 pesticides. This valuable book can be used as reference for not only university students, but also technical personnel of different specialties who are engaged with study and applications, such as food safety, agricultural environment protection, pesticide development, and utilization in scientific research units, institutions and quality inspection organizations.

  • Marine enzymes and specialized metabolism - Part B

    • 1 Edición
    • Volumen 605
    • Inglés
    Marine enzymes and specialized metabolism - Part B, Volume 605 in the Methods in Enzymology series, highlights experimental methods on diverse marine enzymes involved in the construction of bioactive natural product molecules. Unique sections in this new release include discussions on polysaccharide-degra... enzymes from marine gastropods, radical SAM epimerases from sponge microbes, DMS/P demethylase in bacteria, reconstitution of particulate methane monooxygenase into membrane mimetics, the structure and function of cyanobactin enzymes, marine cyanobacterial polyketide beta-branching enzymology, marine cyanobacterial PKS-NRPS enzymology and structural biology, biochemical profiling of DMSP lyases, and more.

  • Transfusion Medicine for Pathologists

    A Comprehensive Review for Board Preparation, Certification, and Clinical Practice
    • 1 Edición
    • Brian Castillo + 4 más
    • Inglés
    Transfusion Medicine for Pathologists: A Comprehensive Review for Board Preparation, Certification, and Clinical Practice is a concise study guide designed to complement standard textbooks in the field of clinical pathology. Pathology residents and fellows of transfusion medicine will find this book useful as a preparation tool for their exams. In addition, the book is a valuable timesaver for busy residents looking for a focused and compact study guide on transfusion medicine that will also be ideal for practicing pathologists who cross-cover transfusion medicine in their clinical practice.

  • Fibroblast Growth Factors

    • 1 Edición
    • Xiaokun Li
    • Inglés
    Fibroblast Growth Factors presents research and results from the leading global research group on FGF, providing up-to-date and comprehensive coverage of the field. The book describes the history, basic research and growth engineering technology involved with FGFs, while also introducing detailed research methods. It comprises eight chapters that detail successes and problems in relation to wound healing of engineered growth factors and considers injury repair and regeneration, non-mitogenic mutants, structure modification, pathology, physiology, pharmacology, development, FGF/FGFR inhibitors, bioengineering, and new drug development. It will serve as a key reference book for researchers working on FGFs.

  • Studies on Hepatitis Viruses

    Life Cycle, Structure, Functions, and Inhibition
    • 1 Edición
    • Satya Prakash Gupta
    • Inglés
    Studies on Hepatitis Viruses: Life Cycle, Structure, Functions, and Inhibition presents the latest on this systemic infection that predominantly affects the liver with inflammation that can be acute or chronic. Hepatitis viruses have been the subject of intense study in the last twenty years, with a wealth of information related to their lifecycle, structure, functions and inhibition being presented. This book compiles the most important developments and research, giving users a very useful guide on this evolving area of virology and medicinal chemistry.

  • Food Fortification in a Globalized World

    • 1 Edición
    • M.G.Venkatesh Mannar + 1 más
    • Inglés
    Food Fortification in a Globalized World outlines experiences over the past 50 years—and future potential—for the application of food fortification across a variety of foods in the industrialized and developing world. The book captures recent science and applications trends in fortification, including emerging areas such as biofortification, nutraceuticals and new nutrient intake recommendations, standards, policy and regulation. The book proposes a balanced and effective food fortification strategy for nations to adopt. In covering the most technical scientific details in an approachable style, this work is accessible to a range of practitioners in industry, government, NGOs, academia and research. Food fortification has become an increasingly significant strategy to address gaps in micronutrient intakes in populations with measurable impact in both industrialized and developing countries. While the positive impacts are well recognized there are new concerns in some countries that excessive fortification of foods, outdated nutritional labeling rules and misleading marketing tactics used by food manufacturers may result in young children consuming harmful amounts of some vitamins and minerals.

  • Genomic Medicine in Emerging Economies

    Genomics for Every Nation
    • 1 Edición
    • George P. Patrinos + 1 más
    • Inglés
    Originally thought to be available only to the world’s wealthiest nations, genomic medicine has developed into a broad range of clinical methods and technologies whose concrete applications are also revolutionizing health systems in many of the world’s resource-limited nations. Genomic Medicine in Emerging Economies: Genomics for Every Nation provides in-depth analysis and key examples of the implementation of medical genomics in low-income nations across the globe, demonstrating how this advancing medical science has already transformed health systems and led to improved patient care in Indonesian, Chilean, Malaysian, Argentinian, Chinese, Sri Lankan, and Colombian populations among others. In addition to defining tools, diagnostics, and treatment pathways at the population-wide level for medical geneticists, genomic researchers, and public health workers to apply in their own work, this book offers an essential, case-study based approach needed to understand how genomic medicine can be used to improve disease-management in a diverse range of economic and social contexts.

  • Post-Authorization Safety Studies of Medicinal Products

    The PASS Book
    • 1 Edición
    • Ayad K. Ali + 1 más
    • Inglés
    Post-Authorization Safety Studies of Medicinal Products: The PASS Book bridges the gap in the literature by providing a complete look at post-authorization safety studies and important pharmacoepidemiology and pharmacovigilance aspects. It covers various types and limitations of active surveillance programs, including the use of large databases and disparate data sources for rapid signal detection, as well as novel and advanced design and analysis approaches for causal interference from observational data. This book serves as an important reference for pharmacovigilance scientists and pharmacoepidemiologi... who are searching for the appropriate study design to answer safety research questions. Readers will be able to effectively and efficiently design and interpret findings from post-authorization safety studies with the goal of improving the benefit-risk balance of a drug in order to optimize patient safety.

  • The Neuroscience of Empathy, Compassion, and Self-Compassion

    • 1 Edición
    • Larry Charles Stevens + 1 más
    • Inglés
    The Neuroscience of Empathy, Compassion, and Self-Compassion provides contemporary perspectives on the three related domains of empathy, compassion and self-compassion (ECS). It informs current research, stimulates further research endeavors, and encourages continued and creative philosophical and scientific inquiry into the critical societal constructs of ECS. Examining the growing number of electrocortical (EEG Power Spectral, Coherence, Evoked Potential, etc.) studies and the sizeable body of exciting neuroendocrine research (e.g., oxytocin, dopamine, etc.) that have accumulated over decades, this reference is a unique and comprehensive approach to empathy, compassion and self-compassion.

  • Applications of Nanocomposite Materials in Drug Delivery

    • 1 Edición
    • Inamuddin + 2 más
    • Inglés
    Applications of Nanocomposite in Drug Delivery discusses and explores the applications of nanocomposites in the area of drug delivery. Starting with a scientific understanding of drug delivery fundamentals, the book explores the utility of nanocomposites in the area of controlled, transdermal, osteo-articular tuberculosis and stimulus sensitive drug delivery applications. The book intricately details and discusses a variety of methods for their preparation, while also highlighting specific applications of nanocomposites in targeted drug delivery.

  • Asiatic Liver Fluke - From Basic Science to Public Health, Part A

    • 1 Edición
    • Volumen 101
    • Inglés
    Asiatic Liver Fluke - From Basic Science to Public Health, Volume 101, is a well-known and respected outlet for detailed and comprehensive reviews written by experts covering all aspects of parasitology. This latest release covers topics of interest, including the Taxonomy, ecology and population genetics of Opisthorchis viverrini and its intermediate hosts, the Epidemiology, geospatial analysis of Opisthorchis viverrini infection and climate change effects in the Mekong basin, Reservoir species and transmission of Opisthorchis viverrini, The draft genome of Opisthorchis viverrini, Functional genomics and genetic manipulation of Opisthorchis viverrini, Microbiomes and liver fluke infection, and more.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 103
    • Inglés
    Advances in Applied Microbiology, Volume 103, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters on antimicrobial resistance in Campylobacter species, microbial source tracking, modeling phage bacteria interactions, and bacterial anaerobic synthesis gas (syngas) and CO2 + H2 fermentation. Each eclectic volume in this series is supplemented by thematic volumes in areas such as Archaea and sick building syndrome.

  • Environmental Virology and Virus Ecology

    • 1 Edición
    • Volumen 101
    • Inglés
    Environmental Virology, Volume 101, the latest in the Advances in Virus Research series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Updates to this release include sections on the host landscape and vector behavior, key determinants of plant virus evolution and emergence, plant virome analysis using spatial metagenomics, host range evolution in generalist viruses, the influence of environment, water-mediated spread and transmission of viruses, viruses transmitted by means other than insect vectors, and more.

  • Hemophilia and Von Willebrand Disease

    Factor VIII and Von Willebrand Factor
    • 1 Edición
    • David Green
    • Inglés
    Hemophilia and Von Willebrand Disease: Factor VIII and Von Willebrand Factor serves as a must-have reference on the important role these essential blood-clotting proteins play in research and clinical medicine. Clinicians and researchers face the daily challenge of staying current on the vast amounts of research that is now generated. The reference to Janus in the title refers to the two roles of the Factor VIII/Von Willebrand Factor Complex: initiation of coagulation and propagation of clot formation. The complex prevents bleeding in hemophilia and Von Willebrand disease but also augments arterial and venous thrombosis.

  • Perinatal Stem Cells

    Research and Therapy
    • 1 Edición
    • Anthony Atala + 4 más
    • Inglés
    Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry.

  • Ancestral DNA, Human Origins, and Migrations

    • 1 Edición
    • Rene J. Herrera + 1 más
    • Inglés
    Ancestral DNA, Human Origins, and Migrations describes the genesis of humans in Africa and the subsequent story of how our species migrated to every corner of the globe. Different phases of this journey are presented in an integrative format with information from a number of disciplines, including population genetics, evolution, anthropology, archaeology, climatology, linguistics, art, music, folklore and history. This unique approach weaves a story that has synergistic impact in the clarity and level of understanding that will appeal to those researching, studying, and interested in population genetics, evolutionary biology, human migrations, and the beginnings of our species.

  • An Overview of FDA Regulated Products

    From Drugs and Cosmetics to Food and Tobacco
    • 1 Edición
    • Eunjoo Pacifici + 1 más
    • Inglés
    Approx.270 pages

  • Biochemical, Physiological and Molecular Avenues for Combating Abiotic Stress in Plants

    • 1 Edición
    • Shabir Hussain Wani
    • Inglés
    Biochemical, Physiological and Molecular Avenues for Combating Abiotic Stress in Plants is a must-have reference for researchers and professionals in agronomy, plant science and horticulture. As abiotic stress tolerance is a constant challenge for researchers and professionals working on improving crop production, this book combines recent advances with foundational content, thus offering in-depth coverage on a variety of abiotic stress tolerance mechanisms that help us better understand and improve plant response and growth under stress conditions. The mechanisms explored in this book include stress perception, signal transduction and synthesis of stress-related proteins and other molecules. In addition, the book provides a critical understanding of the networks of genes responsible for abiotic stress tolerance and their utilization in the development of stress tolerance in plants. Practical breeding techniques and modern genetic analyses are also discussed.

  • The Cellular Secretome and Organ Crosstalk

    • 1 Edición
    • Juergen Eckel
    • Inglés
    The Cellular Secretome and Organ Crosstalk focuses on the release of peptides and proteins from different organs and their specific functions in metabolic regulation and cell- and organ crosstalk. The book is written for experts in the field, however, for each topic, helpful references are included. The book also includes technical sections that summarize the state-of-the-art of secretome and crosstalk analysis. This book fulfills the need for a resource that comprehensively describes the current knowledge of secretome biology in health and disease. Communication between different organs involves lipids and other small molecules and a host of proteins and peptides comprising the secretome of different organs (organokinome). More than 600 adipokines have been identified, and an increasing number of hepatokines and myokines have recently been discovered with mostly unknown physiological impact. Importantly, an aberrant signature of the organokinome may be critically underlying a variety of metabolic diseases and may determine the individual susceptibility to disease development.

  • Edible Oleogels

    Structure and Health Implications
    • 2 Edición
    • Alejandro G. Marangoni + 1 más
    • Inglés
    Edible Oleogels, Structure and Health Implications, Second Edition presents a novel strategy on how to eliminate trans fats from our diets. Topics covered include how to avoid excessive amounts of saturated fat by structuring oil to make it behave like crystalline fat and how to develop trans fat free, low saturate, functional shortenings for the food industry. The major approach to form these materials is covered, helping manufacturers incorporate specific molecules (polymers, amphiphiles, waxes) into oil components. As such, this an ideal resource for those in product development and anyone interested in understanding the role of trans and saturated fats in health and nutrition. In an effort to provide alternatives to trans and saturated fats, scientists have been busy modifying the physical properties of oils to resemble those of fats. Many food products requiring a specific texture and rheology can be made with these novel oil-based materials without causing significant changes to final product quality. Hence, this book provides a valuable resource on new advancements.

  • Structure-Function Analysis of Edible Fats

    • 2 Edición
    • Alejandro G. Marangoni
    • Inglés
    Structure-Function Analysis of Edible Fats, Second Edition summarizes the latest approaches in the quantification of the physical structure of fats and its relationship to macroscopic functionality. The book takes a proven, general approach, presenting principles and techniques in a way that can be applied to any lipidic material. As the maturity of the field has increased since the first edition, there is an increased need for more sophisticated quantitative approaches to common problems encountered by industry. This book outlines modern methods used for this purpose by some of the leading authorities in the field today. Edited by expert Alejandro Marangoni, and with contributions from leaders in field, the book features the latest developments, including chapters on Phase Behavior of Fat Mixtures and the Rheology and Mechanical Properties of Fats Methods Used in the Study of the Physical Properties of Fats (including a new section on microscopy).

  • Bipolar Disorder Vulnerability

    Perspectives from Pediatric and High-Risk Populations
    • 1 Edición
    • Jair Soares + 2 más
    • Inglés
    Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.

  • Applied Biomechatronics Using Mathematical Models

    • 1 Edición
    • Jorge Garza Ulloa
    • Inglés
    Applied Biomechatronics Using Mathematical Models provides an appropriate methodology to detect and measure diseases and injuries relating to human kinematics and kinetics. It features mathematical models that, when applied to engineering principles and techniques in the medical field, can be used in assistive devices that work with bodily signals. The use of data in the kinematics and kinetics analysis of the human body, including musculoskeletal kinetics and joints and their relationship to the central nervous system (CNS) is covered, helping users understand how the complex network of symbiotic systems in the skeletal and muscular system work together to allow movement controlled by the CNS. With the use of appropriate electronic sensors at specific areas connected to bio-instruments, we can obtain enough information to create a mathematical model for assistive devices by analyzing the kinematics and kinetics of the human body. The mathematical models developed in this book can provide more effective devices for use in aiding and improving the function of the body in relation to a variety of injuries and diseases.

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