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Elsevier

Libros en Ciencias de la Vida

  • Endocrine Biomarkers

    Clinicians and Clinical Chemists in Partnership
    • 1 Edición
    • Hossein Sadrzadeh + 1 más
    • Inglés
    Endocrine Biomarkers: Clinical Aspects and Laboratory Determination covers all the pre-analytical variables that can affect test results, both in the clinic and laboratory. Biomarkers of endocrine and bone diseases are discussed from both clinical and laboratory perspectives, and the authors elaborate on the teamwork-based app+roach between the clinician and the laboratory professional in the diagnosis and management of endocrine and bone disorders. Discussions include test utilization, laboratory measurement methods, harmonization and standardization, interpretation of results, and reference intervals. Each chapter ends with a discussion of one or two relevant cases with shared opinions from both a clinician and a clinical chemist. Each chapter also includes a summary box outlining key points and common pitfalls in the use of specific disease biomarkers and tests.

  • Therapeutic Foods

    • 1 Edición
    • Volumen 8
    • Alexandru Mihai Grumezescu + 1 más
    • Inglés
    Therapeutic Foods, Volume 8 in the Handbook of Food Bioengineering series, is an essential resource for anyone investigating foods that may be utilized as therapeutic agents. Plants and animal products have been utilized since ancient times as medicine to treat diseases, and the properties within foods and ingredients are still investigated for food therapy and prophylaxis. The book is a comprehensive resource for researchers and scientists already in the field or those just entering. It covers many spices, plant extracts, essential oils and vegetal mixtures that have immune-stimulatory effects and can be efficiently utilized in the treatment of infections and cancer.

  • G Protein-Coupled Receptors in Immune Response and Regulation

    • 1 Edición
    • Volumen 136
    • Inglés
    G Protein-Coupled Receptors in Immune Response and Regulation, Volume 136 presents emerging concepts related to the role of GPCRs in immune response and regulation. Users will find updated chapters on a variety of topics, including Beta-adrenergic signaling in the onset and progression of asthma, the Emerging roles of Regulators of G protein signaling (RGS) proteins in the immune system, information on Kinin receptors in immune response and pathogenic infections, and sections on GPCR signaling in C. elegans and its implications in immune response, GPCR Kinases in Inflammatory response and signaling, and GRK2 in Inflammation: Regulation of T cell receptors and IgE signaling. Chapters in this book discuss not only the well-known aspects of GPCR signaling in immunology, but also presents many emerging paradigms that have not yet been reported in classical textbooks. Each chapter presents a forward-looking discussion, providing a glimpse of the tremendous potential associated with the specific receptor systems discussed.

  • Functionalised Cardiovascular Stents

    • 1 Edición
    • Gerard Wall + 2 más
    • Inglés
    Cardiovascular disease is a major cause of mortality in the western world and about half of these deaths are caused by coronary artery disease. One of the most commonly used interventions to treat arterial blockages is to deploy an arterial stent to keep the vessel open. Traditionally, some cardiovascular stents have been associated with serious side-effects, such as thrombosis. This book describes the fundamentals of cardiovascular stents, technologies to functionalize their surfaces and the market status of these important implants. The chapters provide specific focus on the production and evolution of cardiovascular stents, providing essential knowledge for researchers on advances in the field and knowledge of how cardiovascular stents are currently being "functionalized" in order to improve their biocompatibility and minimize negative outcomes in vivo.

  • SPEC – Handbook of Clinical Neurology, Volume 144, Huntington Disease, 12-Month Access, eBook

    • 1 Edición
    • Volumen 144
    • Inglés
    Huntington Disease summarizes the most recent findings related to the disease, providing both cutting edge coverage for clinical/research specialists looking to expand their knowledge base of Huntington disease information, as well as solid groundwork for advanced students from various backgrounds (neurology, psychiatry, neuropsychology, genetics). The volume includes all major areas of Huntington disease clinical care and research, whereas many other HD texts focus solely on neurological symptoms. This book also addresses behavioral and cognitive symptoms, brain imaging, and family dynamics and therapeutic alliances in working with individuals affected by HD. Clinical trials are covered extensively, including design considerations for therapeutic studies. The devastating nature of Huntington’s disease is well appreciated throughout the neuroscience, neurology, and psychiatric communities, and a great amount of basic and clinical research is currently taking place. However, much of that occurs in isolated research silos, and it is critical that an interdisciplinary resource be developed to provide in depth information to enhance communication and collaboration. This volume in the Handbook of Clinical Neurology series is that resource.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 146
    • Inglés
    Advances in Agronomy, Volume 146 is the latest in a series that continues to be recognized as a leading reference for the latest research in agronomy. Updated chapters in this new release include the Significance and Role of Si in Crop Production, National Comparison of the Total and Sequestered Organic Matter Contents of Conventional and Organic Farm Soils, Purine – N Metabolism in Drought or Salinity Challenged Food Security Crops, Plant Rooting and Cropping Systems Management to Improve N Use Efficiency, and The Important Role of Layered Double Hydroxides in Soil Chemical Processes and Remediation: What We Have Learned Over the Past 20 Years. Each volume in the evolving series contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Federal Data Science

    Transforming Government and Agricultural Policy Using Artificial Intelligence
    • 1 Edición
    • Feras A. Batarseh + 1 más
    • Inglés
    Federal Data Science serves as a guide for federal software engineers, government analysts, economists, researchers, data scientists, and engineering managers in deploying data analytics methods to governmental processes. Driven by open government (2009) and big data (2012) initiatives, federal agencies have a serious need to implement intelligent data management methods, share their data, and deploy advanced analytics to their processes. Using federal data for reactive decision making is not sufficient anymore, intelligent data systems allow for proactive activities that lead to benefits such as: improved citizen services, higher accountability, reduced delivery inefficiencies, lower costs, enhanced national insights, and better policy making. No other government-dedicated work has been found in literature that addresses this broad topic. This book provides multiple use-cases, describes federal data science benefits, and fills the gap in this critical and timely area. Written and reviewed by academics, industry experts, and federal analysts, the problems and challenges of developing data systems for government agencies is presented by actual developers, designers, and users of those systems, providing a unique and valuable real-world perspective.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 98
    • Inglés
    Advances in Parasitology, Volume 98, first published in 1963, contains comprehensive and up-to-date reviews on all areas of interest in contemporary parasitology. The latest release in this series contains chapters on The battle against flystrike – past research and new prospects through genomics, Life history, systematics and evolution of the Diplostomoidea Poirier, 1886: progress, promises and challenges emerging from molecular studies, Hook, line and infection: a guide to culturing parasites, establishing infections and assessing immune responses in the three-spined stickleback, and Trypanosoma congolense: a molecular toolkit and resources for studying a major livestock pathogen and model trypanosome. The series includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications.

  • Neuroepidemiology in Tropical Health

    • 1 Edición
    • Pierre-Marie Preux + 1 más
    • Inglés
    Neuroepidemiology in Tropical Health covers major neurological diseases of relevance in tropical settings and examines the specificities of epidemiology of neurological diseases in the context of tropical countries that face many challenges when compared to the developed world. Part One focuses on methods and their eventual specificities, and how such methods, like sampling, can be adapted for specific scenarios. Parts Two and Three discuss environmental factors and their consequences for neurology in the tropical world, as well as large geographical areas and their specificities. Finally, Part Four presents relevant neurological diseases in in-depth chapters. This invaluable information will help readers recognize the various neurological conditions presented, with the inclusion of their aetiologies and treatment in tropical areas. The book therefore fills a gap in the neuroepidemiology literature, with chapters written by an international collection of experienced authors in the field.

  • Innovative Technologies for Food Preservation

    Inactivation of Spoilage and Pathogenic Microorganisms
    • 1 Edición
    • Francisco J. Barba + 3 más
    • Inglés
    Innovative Technologies for Food Preservation: Inactivation of Spoilage and Pathogenic Microorganisms covers the latest advances in non-thermal processing, including mechanical processes (such as high pressure processing, high pressure homogenization, high hydrodynamic pressure processing, pressurized fluids); electromagnetic technologies (like pulsed electric fields, high voltage electrical discharges, Ohmic heating, chemical electrolysis, microwaves, radiofrequency, cold plasma, UV-light); acoustic technologies (ultrasound, shockwaves); innovative chemical processing technologies (ozone, chlorine dioxide, electrolysis, oxidized water) and others like membrane filtration and dense phase CO2. The title also focuses on understanding the effects of such processing technologies on inactivation of the most relevant pathogenic and spoilage microorganisms to ensure food safety and stability. Over the course of the 20th century, the interest and demand for the development and application of new food preservation methods has increased significantly. The research in the last 50 years has produced various innovative food processing technologies and the use of new technologies for inactivation of spoilage and/or pathogenic microorganisms will depend on several factors. At this stage of development there is a need to better understand the mechanisms that govern microbial inactivation as induced by new and innovative processing technologies, as well as suitable and effective conditions for inactivating the microorganism.

  • Advances in Genetics

    • 1 Edición
    • Volumen 98
    • Inglés
    Advances in Genetics, Volume 98 provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions. Topics of interest in this updated volume include the Genetics of Mitochondrial Disease, a Genetic analysis of depression, happiness and other normal personality traits, The Evolving Centromere and Kinetochore, and The Genetics of Parkinson’s Disease.

  • Basic Finite Element Method as Applied to Injury Biomechanics

    • 1 Edición
    • King-Hay Yang
    • Inglés
    Basic Finite Element Method as Applied to Injury Biomechanics provides a unique introduction to finite element methods. Unlike other books on the topic, this comprehensive reference teaches readers to develop a finite element model from the beginning, including all the appropriate theories that are needed throughout the model development process. In addition, the book focuses on how to apply material properties and loading conditions to the model, how to arrange the information in the order of head, neck, upper torso and upper extremity, lower torso and pelvis and lower extremity. The book covers scaling from one body size to the other, parametric modeling and joint positioning, and is an ideal text for teaching, further reading and for its unique application to injury biomechanics. With over 25 years of experience of developing finite element models, the author's experience with tissue level injury threshold instead of external loading conditions provides a guide to the "do’s and dont's" of using finite element method to study injury biomechanics.

  • The Bifidobacteria and Related Organisms

    Biology, Taxonomy, Applications
    • 1 Edición
    • Paola Mattarelli + 3 más
    • Inglés
    The Bifidobacteria and Related Organisms: Biology, Taxonomy, Applications brings together authoritative reviews on all aspects of Bifidobacteria and related genera. Their place within the Phylum Actinobacteria is discussed first, and this is followed by descriptions of the genera Bifidobacterium, Alloscardovia, Aeriscardovia, Bombiscardovia, Gardnerella, Metascardovia, Parascardovia and Scardovia and the currently accredited species within those genera. The increased availability of genome sequences and molecular tools for studying bifidobacteria provides important information about their taxonomy, physiology and interactions with their host. Also considerations about common bifidobacterial core maintenance during the mutual coevolution of a host and its intestinal microbes could be relevant for health claims for the ability of symbiotic gut bacteria to provide health benefits to their host, and for evaluating such claims in scientifically valid experiments. Chemotaxonomy is important to our understanding of these genera and so is considered along with physiological and biochemical aspects before proceeding to examine clinical and other practical aspects. The ability to maintain pure cultures and to grow cells in industrial quantities when required for applications requires that the cells’ environmental and nutritional needs are well understood. Some species are important clinically and as animal digestive tract synbionts—and even play a part in honey production—so these matters are considered along with milk oligosaccharides’ roles in gut flora development in neonates.

  • History of Risk Assessment in Toxicology

    • 1 Edición
    • Sol Bobst
    • Inglés
    History of Risk Assessment in Toxicology guides the reader through the historical narrative of the evolution of risk assessment thinking in human and environmental practices. Risk assessment concepts are used in many different professional practice areas. In the health and environmental practices of risk assessment, the critical issue is often what chemical concentration in air, water, food, or a solid substance is acceptable, or considered not to result in any adverse effect. The book reviews examples from early scientific and health studies to showcase the foundations of risk assessment. The book also explores the development of risk assessment as practiced by major regulatory bodies such as the US Food and Drug Administration (FDA), the Occupational Safety & Health Administration (OSHA), and the US Environmental Protection Agency (EPA) to reveal how risk assessment has evolved in the 20th and 21st centuries. Modern technology has created opportunities in silicon in vitro, computational modeling, omics, and big data techniques to assess the toxicity of chemicals, while traditional approaches to risk assessment are being challenged with new and innovative approaches. Finally, current issues being debated and tested in risk assessment are outlined with possible future avenues suggested.

  • Mechanical Circulatory and Respiratory Support

    • 1 Edición
    • Shaun D. Gregory + 2 más
    • Inglés
    Mechanical Circulatory and Respiratory Support is a comprehensive overview of the past, present and future development of mechanical circulatory and respiratory support devices. Content from over 60 internationally-reno... experts focusses on the entire life-cycle of mechanical circulatory and respiratory support – from the descent into heart and lung failure, alternative medical management, device options, device design, implantation techniques, complications and medical management of the supported patient, patient-device interactions, cost effectiveness, route to market and a view to the future. This book is written as a useful resource for biomedical engineers and clinicians who are designing new mechanical circulatory or respiratory support devices, while also providing a comprehensive guide of the entire field for those who are already familiar with some areas and want to learn more. Reviews of the most cutting-edge research are provided throughout each chapter, along with guides on how to design new devices and which areas require specific focus for future research and development.

  • Kent’s Technology of Cereals

    An Introduction for Students of Food Science and Agriculture
    • 5 Edición
    • Kurt A. Rosentrater + 1 más
    • Inglés
    Kent’s Technology of Cereals: An Introduction for Students of Food Science and Agriculture, Fifth Edition, is a classic and well-established book that continues to provide students, researchers and practitioners with an authoritative and comprehensive study of cereal technology. This new edition has been thoroughly updated with new sections, including extrusion cooking and the use of cereals for animal feed. In addition, it offers information on statistics, new products, the impact of climate changes and genetics, new economic trends, nutrition regulations and new technologies. The book is useful for students, researchers, and industrial practitioners alike, covering the full spectrum of cereal grain production, processing, and use for foods, feeds, fuels, industrial materials, and other uses.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 82
    • Inglés
    Advances in Clinical Chemistry, Volume 82, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. This updated volume includes chapters on Calcium and Bone Metabolism Indices, Cytokines and MicroRNA in Coronary Artery Disease, Biological and molecular characterization of circulating tumor cells: A creative strategy for precision medicine?, Towards a blood-borne biomarker of chronic hypoxemia: Red cell distribution width and respiratory disease, miRNAs: nanomachines that microManage the pathophysiology of Diabetes mellitus, and Fortilin, A Potential Target for the Prevention and Treatment of Human Diseases. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Environmental Factors in Neurodegenerative Diseases

    • 1 Edición
    • Volumen 1
    • Inglés
    Environmental Factors in Neurodegenerative Diseases, Volume One addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson’s disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike.

  • Computational Psychiatry

    Mathematical Modeling of Mental Illness
    • 1 Edición
    • Alan Anticevic + 1 más
    • Inglés
    Computational Psychiatry: Mathematical Modeling of Mental Illness is the first systematic effort to bring together leading scholars in the fields of psychiatry and computational neuroscience who have conducted the most impactful research and scholarship in this area. It includes an introduction outlining the challenges and opportunities facing the field of psychiatry that is followed by a detailed treatment of computational methods used in the service of understanding neuropsychiatric symptoms, improving diagnosis and guiding treatments. This book provides a vital resource for the clinical neuroscience community with an in-depth treatment of various computational neuroscience approaches geared towards understanding psychiatric phenomena. Its most valuable feature is a comprehensive survey of work from leaders in this field.

  • Chemical Glycobiology

    Synthesis, Manipulation and Applications of Glycans
    • 1 Edición
    • Volumen 597
    • Inglés
    Chemical Glycobiology, Volume 597, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume, the first on chemical glycobiology, contains comprehensive chapters on the Discovery of New Glycosidases from Metagenomic Libraries, Structure-guided directed evolution of glycosidases: A case study in engineering a blood group antigen-cleaving enzyme, A Pipeline for Studying and Engineering Single-Subunit Oligosaccharyltransf... Directed evolution of glycopeptides using mRNA display, Chemoenzymatic Synthesis and Applications of Prokaryote-Specific UDP-Sugars, and Biosynthesis of Legionaminic Acid and its Incorporation into Glycoconjugates. Readers will find the latest information on this developing area of research, as reported by leaders in the field.

  • Gas Bubble Dynamics in the Human Body

    • 1 Edición
    • Saul Goldman + 2 más
    • Inglés
    Gas Bubble Dynamics in the Human Body provides a broad range of professionals, from physicians working in a clinic, hospital or hyperbaric facility, to physical scientists trying to understand and predict the dynamics of gas bubble behavior in the body, with an interdisciplinary perspective on gas-bubble disease. Both iatrogenic and decompression-induce... gas bubbles are considered. The basic medical and physiological aspects are described first, in plain language, with numerous illustrations that facilitate an intuitive grasp of the basic underlying medicine and physiology. Current issues in the field, particularly microbubbles and microparticles, and their possible role in gas-bubble disease are included. The physical and mathematical material is given at several levels of sophistication, with the "hard-core" math separated out in sections labelled "For the Math Mavens", so that the basic concepts can be grasped at a descriptive level. The field is large and multi-disciplinary, so that some of the discussion that is at a greater depth is given separately in sections labelled "In Greater Detail". Skipping these sections for whatever reason, shouldn’t materially hamper acquiring an overall appreciation of the field.

  • Animals and Human Society

    • 1 Edición
    • Colin G. Scanes + 1 más
    • Inglés
    Animals and Human Society provides a solid, scientific, research-based background to advance understanding of how animals impact humans. Animals have had profound effects on people from the earliest times, ranging from zoonotic diseases, to the global impact of livestock, poultry and fish production, to the influences of human-associated animals on the environment (on extinctions, air and water pollution, greenhouse gases, etc.), to the importance of animals in human evolution and hunter -gatherer communities.As a resource for both science and non-science, Animals and Human Society can be used as a text for courses in Animals and Human Society or Animal Science, or as supplemental material for Introduction to Animal Science. It offers foundational background to those who may have little background in animal agriculture and have focused interest on companion animals and horses. The work introduces livestock production (including poultry and aquaculture) but also includes coverage of companion and lab animals. In addition, animal behavior and animal perception are covered.Animals and Human Society is likewise an excellent resource for researchers, academics, or students newly entering a related field or coming from another discipline and needing foundational information, as well as interested laypersons looking to augment their knowledge on the many impacts of animals in human society.

  • Natural and Artificial Flavoring Agents and Food Dyes

    • 1 Edición
    • Volumen 7
    • Alexandru Mihai Grumezescu + 1 más
    • Inglés
    Natural and Artificial Flavoring Agents and Dyes, Volume 7 in the Handbook of Food Bioengineering series, examines the use of natural vs. artificial food dyes and flavors, highlighting some of the newest production and purification methods. This solid resource explores the most recent trends and benefits of using natural agents over artificial in the production of foods and beverages. Using the newest technologies and evidence-based research methods, the book demonstrates how natural flavoring agents and dyes can be produced by plants, microorganisms and animals to produce higher quality foods that are more economical and safe to the consumer.

  • Why Penguins Communicate

    The Evolution of Visual and Vocal Signals
    • 1 Edición
    • Pierre Jouventin + 1 más
    • Inglés
    Why Penguins Communicate: The Evolution of Visual and Vocal Signals is a comprehensive and condensed review of several hundred publications on the evolution of penguin behaviors, particularly signaling, linking genetics and ecology via such behavioral adaptations as nuptial displays. This exciting work has developed from the authors’ many years researching on the behavioral strategies of penguins, such as the unique vocal signatures for individual recognition. Studies of penguins on islands surrounding Antarctica are presented, fully showcasing the behavioral significance of visual ornaments (mating displays) and how and why penguins behave via adaptive evolutionary explanations. Through this evolutionary lens, the authors address several questions involving their identification and taxonomy, habitat and location, breeding, and differences between penguins and other seabirds. Each species occupies a unique ecological niche, and behaviors permit separating the species through mutual display. Although model organisms in science are diverse and specialized, we see the entire integration in penguins, from acoustical and optical physics, to behavioral display and speciation. This work highlights the adaptive significance of their behavior through an evolutionary point- of-view.

  • Transfusion Medicine, Apheresis, and Hemostasis

    Review Questions and Case Studies
    • 1 Edición
    • Huy P. Pham + 1 más
    • Inglés
    Transfusion Medicine, Apheresis, and Hemostasis: Review Questions and Case Studies is the collaborative effort that spanned a time period of 2 years and included 50 experts, many whom are national leaders in their respected fields. It also represents the passion and privilege we feel to teach the next generation of physicians in Transfusion Medicine and Apheresis.The main goal for this book is to help the readers build a solid foundation of both basic and advanced conceptual knowledge to prepare for the American Board of Pathology (ABP) certification exam in Transfusion Medicine. This book is not intended to be a substitute for textbooks, original research or review articles, and/or clinical training. Further, since the field of medicine, both from a scientific and regulatory perspective, rapidly changes, the readers are advised to continuously update their knowledge by attending national meetings and reading clinical journals. To equip the readers with the basic knowledge in critical reading and data analysis, which is an essential skill in daily medical practice, a novel chapter titled “Data Interpretation in Laboratory Medicine” was included in this book. In this chapter, the readers are asked to make logical conclusions based on the given data and/or statistical results. Moreover, there is also a chapter on “Practical Calculations in Transfusion Medicine, Apheresis, and Hemostasis” to help consolidate all the necessary formulas commonly used in daily practice for easy reference. These chapters are unique to our book and will not be found in any other currently on the market.All of the questions in this book were originally created by the authors of each chapter. Each question can either be standalone or part of a case scenario representing challenge cases in Transfusion Medicine, Apheresis, and Hemostasis. These questions often represent both rare and common clinical scenarios that the authors have seen during their clinical practice. Each question is then followed by 5 possible answers, with only one being correct (or the best answer). After the question, there is a conceptual explanation followed by a more factual explanation of the right and wrong answers. We gave the individual authors the freedom to choose how they explained the wrong answer choices. Some authors chose to be more direct (e.g. Answer A is incorrect because…), while other authors chose a more conversational style (e.g. Human resources (answer A) includes staffing, selection, orientation, training, and competency assessment of employees). This format is designed to help the student linking the conceptual and factual knowledge together to form a solid foundation for use in clinical practice. At the end of each chapter, there is a list of articles and textbooks that will prove useful to the motivated student who wishes to become an expert in the field. Another special feature to our textbook is the presence of a pre-test and post-test, which are provided to help the readers with self-assessment.As stated above, the main focus of this book is to help the readers preparing for the ABP certification exam in Transfusion Medicine. However, due to the interdisciplinary nature of the field of Transfusion Medicine, Apheresis, and Hemostasis, we believe that this book is also beneficial to and can be used by all clinicians involved in the management of complex transfusion, apheresis, and hemostasis issues, such as hematologists, anesthesiologists, surgeons, and critical care physicians. We further believe that it is a helpful guide for these specialists to prepare for their own specialty certification exam, when the topics are related to Transfusion Medicine, Apheresis, and Hemostasis.

  • Advances in Molecular Toxicology Vol 11

    • 1 Edición
    • Volumen 11
    • Inglés
    Advances in Molecular Toxicology, Volume 11, features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment, and produced by the human body, manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events are also reviewed by leading experts in the field.

  • Chordomas and Chondrosarcomas of the Skull Base and Spine

    • 2 Edición
    • Griffith R. Harsh IV + 1 más
    • Inglés
    Chordomas and Chondrosarcomas of the Skull Base and Spine, Second Edition, is a major reference and guide for neurosurgeons, medical oncologists, neuroscientists, orthopedic surgeons, head and neck surgeons and radiation oncologists that treat patients and research chordomas and chondrosarcomas of the axial skeleton. This book is the unique result of the collaboration of multidisciplinary specialists from a wide variety of fields (neurological sciences, medical oncology, molecular biology, orthopedics and radiation oncology), offering the most relevant information about chordomas and chondrosarcomas of the axial skeleton from each of these fields condensed into one single volume. It contains new medical knowledge and scientific advances regarding the treatment of these types of tumors. Additionally, the book includes chapters written by the Chordoma Foundation and Sarcoma Foundation of America, providing the most valuable information and support for patients and their relatives.

  • New and Future Developments in Microbial Biotechnology and Bioengineering

    Penicillium System Properties and Applications
    • 1 Edición
    • Vijai G. Gupta + 1 más
    • Inglés
    New and Future Developments in Microbial Biotechnology and Bioengineering: Penicillium System Properties and Applications covers important research work on the applications of penicillium from specialists from an international perspective. The book compiles advancements and ongoing processes in the penicillium system, along with updated information on the possibilities for future developments. All chapters are derived from current peer reviewed literature as accepted by the international scientific community. These important fungi were found to secrete a range of novel enzymes and other useful proteins, and are still being extensively studied and improved for specific use in the food, textile, pulp and paper, biocellulosic ethanol production and other industries. The book caters to the needs of researchers/academic... dealing with penicillium spp. related research and applications, outlining emerging issues on recent advancements made in the area of research and its applications in bioprocess technology, chemical engineering, molecular taxonomy, biofuels/bioenergy research and alternative fuel development. In addition, the book also describes the identification of useful compound combinations/enzyme cocktails and the fermentation conditions required to obtain them at an industrial scale. Finally, the book provides updated information on the best utilization of these fungi as a natural tool to meet the next challenges of biotechnology.

  • Biotechnology for Sustainable Agriculture

    Emerging Approaches and Strategies
    • 1 Edición
    • Ram Lakhan Singh + 1 más
    • Inglés
    Biotechnology for Sustainable Agriculture: Emerging Approaches and Strategies is an outstanding collection of current research that integrates basic and advanced concepts of agricultural biotechnology with future development prospects. Using biotechnology with sustainable agriculture effectively contributes to gains in agricultural productivity, enhanced food security, reduced poverty and malnutrition, and more ecologically sustainable means of food production. Written by a panel of experts, this book is unique in its coverage of the broad area of biotechnology for sustainable agriculture. It includes intriguing topics and discussions of areas such as recombinant DNA technology and genetic engineering.

  • Measurement and Analysis of Kinetic Isotope Effects

    • 1 Edición
    • Volumen 596
    • Inglés
    Experimental Analysis of Enzyme Mechanism Using Isotope Effects, Volume 596, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this comprehensive update include Measurement of enzyme binding isotope effects, Chemical ligation and isotope labeling to locate dynamic effects, Measurement of heavy enzyme isotope effects, Extracting kinetic isotope effects from a global analysis of reaction progress curves, KIE of metabolic flux and enzymes, Solvent and Primary KIE on Flavin Enzymes, and The Rapid Determination of Primary Deuterium Isotope Effects on Enzyme-Catalyzed Proton Transfer at Carbon in 50/50 HOH/DOD. Readers who are interested in applying or understanding this research will find useful methods currently used for measuring isotope effects on solution and enzyme reactions.

  • Current Developments in Biotechnology and Bioengineering

    Current Advances in Solid-State Fermentation
    • 1 Edición
    • Ashok Pandey + 2 más
    • Inglés
    Current Developments in Biotechnology and Bioengineering: Current Advances in Solid-State Fermentation provides knowledge and information on solid-state fermentation involving the basics of microbiology, biochemistry, molecular biology, genetics and principles of genetic engineering, metabolic engineering and biochemical engineering. This volume of the series is on Solid-State fermentation (SSF), which would cover the basic and applied aspects of SSF processes, including engineering aspects such as design of bioreactors in SSF. The book offers a pool of knowledge on biochemical and microbiological aspects as well as chemical and biological engineering aspects of SSF to provide an integrated knowledge and version to the readers.

  • Comparative Mammalian Haematology

    Cellular Components and Blood Coagulation of Captive Wild Animals
    • 1 Edición
    • C. M. Hawkey
    • Inglés
    Comparative Mammalian Haematology: Cellular Components and Blood Coagulation of Captive Wild Mammals presents a critical review of the hematology of the vertebrates. It discusses the characteristics of blood components of primates; the features of the red cells of carnivores; and the different species of canine. The book covers the blood components of cats, monkeys, bears, mouse, horse, rhinoceros, pig, llama, boars, camels, and deer. The book can provide useful information to hematologists, biologists, students, and researchers.

  • The Prevention of Cardiovascular Disease through the Mediterranean Diet

    • 1 Edición
    • Almudena Sánchez Villegas + 1 más
    • Inglés
    The Prevention of Cardiovascular Disease through the Mediterranean Diet presents dietary habits that will have maximum impact on cardiovascular health and other major chronic diseases. Data collected through the results of large clinical trials, such as PREDIMED, one of the longest trials ever conducted, has allowed researchers to conclude that the Mediterranean Diet provides the best evidence for health benefits. Studies have shown that the Mediterranean Diet is able to reduce the risk of cardiovascular hard clinical events by 30%. This book explores the components of this diet, including the consumption of extra virgin olive oil, nuts, fresh fruits and vegetables, fatty fish, poultry and red wine for optimal health benefits.

  • Handbook of Advanced Chromatography /Mass Spectrometry Techniques

    • 1 Edición
    • Michal Holcapek + 1 más
    • Inglés
    Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques.

  • Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging

    Volume 12
    • 1 Edición
    • M. A. Hayat
    • Inglés
    Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic assets’ and promoting cell viability, hence, it has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. As the latest release in the Autophagy book series, users will find a detailed explanation of the role of molecular mechanisms.

  • Staphylococcus aureus

    • 1 Edición
    • Alexandra Fetsch
    • Inglés
    Staphylococcus aureus provides information on food borne outbreaks of disease and their impact on human health. It is for anyone interested in the features of the pathogen, and its food safety aspects, as well as its prevalence and possible control and eradication options. This is a practical reference for those in the food industry, but also includes some theoretical information useful for advising. The book introduces detailed features and molecular biology of the pathogen, as well as selective methods of detection, prevention and eradication essential for research. It covers methicillin-resistan... staphylococcus aureus for food related industries, information on genetic lineages, cell wall components, cell division machinery, molecular characterization, and capillary electrophoresis for detecting and characterizing staphylococcus aureus.

  • The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine

    • 1 Edición
    • Uri Galili
    • Inglés
    The Natural Anti-Gal Antibody as Foe Turned Friend in Medicine provides a comprehensive review of the natural anti-Gal antibody, which is the most abundant antibody in humans constituting ~1% of immunoglobulins and the carbohydrate antigen it recognizes, the α-gal epitope. It discusses the discovery of this antigen/antibody system, its evolution in mammals, the pathological effects of this antibody, and its possible use in various therapies in humans. Most significantly, the book discusses microbial and regenerative therapies in which an antibody present in all humans may be harnessed as an in vivo pharmaceutical agent that enables a wide variety of therapies. Some of these therapies are described as experimental studies that are compiled in this book, other already studied therapies in the area of cancer immunotherapy are also included in this book.

  • Data Literacy

    How to Make Your Experiments Robust and Reproducible
    • 1 Edición
    • Neil Smalheiser
    • Inglés
    Data Literacy: How to Make Your Experiments Robust and Reproducible provides an overview of basic concepts and skills in handling data, which are common to diverse areas of science. Readers will get a good grasp of the steps involved in carrying out a scientific study and will understand some of the factors that make a study robust and reproducible.The book covers several major modules such as experimental design, data cleansing and preparation, statistical analysis, data management, and reporting. No specialized knowledge of statistics or computer programming is needed to fully understand the concepts presented. This book is a valuable source for biomedical and health sciences graduate students andresearchers, in general, who are interested in handling data to make their research reproducibleand more efficient.

  • Northeast Pacific Shark Biology, Research and Conservation Part A

    • 1 Edición
    • Volumen 77
    • Inglés
    Northeast Pacific Shark Biology, Research and Conservation, Part A, Volume 77 highlights the biological attributes of, and the conservation efforts targeted at, populations of vulnerable sharks in the Northeastern Pacific Ocean bordering the west coast of the United States, one of the most economically and ecologically important oceanic regions in the world. Updates in this new volume include chapters on Biodiversity, Conservation and Life History of Northeastern Pacific Chondrichthyans, a Review of current genetic analyses of Northeast Pacific sharks and conservation implications, and a section on the Trophodynamics and ecological impacts of eastern North Pacific sharks.

  • miRNA and Cancer

    • 1 Edición
    • Volumen 135
    • Inglés
    miRNA and Cancer, Volume 135, the latest volume in the Advances in Cancer Research series, provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, and includes specific chapters on Non-coding RNAs as Biomarkers of Cancer, The Enigma of microRNA Regulation in Cancer, Animal Models to Study microRNA functions, Non-coding RNAs and Cancer, microRNAs in Cancer Susceptibility, ts-RNAs versus microRNAs, microRNAs and AML, and microRNAs and Epigenetics.

  • Genetically Engineered Foods

    • 1 Edición
    • Volumen 6
    • Alexandru Mihai Grumezescu + 1 más
    • Inglés
    Genetically Engineered Foods, Volume 6 in the Handbook of Food Bioengineering series, is a solid reference for researchers and professionals needing information on genetically engineered foods in human and animal diets. The volume discusses awareness, benefits vs. disadvantages, regulations and techniques used to obtain, test and detect genetically modified plants and animals. An essential resource offering informed perspectives on the potential implications of genetically engineered foods for humans and society. Written by a team of scientific experts who share the latest advances to help further more evidence-based research and educate scientists, academics and government professionals about the safety of the global food supply.

  • Fe-S Cluster Enzymes Part A

    • 1 Edición
    • Volumen 595
    • Inglés
    Fe-S Cluster Enzymes, Part A, Volume 595 is the first of two volumes focused on Fe-S cluster enzymes. New topics of note in this series include Electrochemistry of Fe/S Proteins, Genetic, biochemical and biophysical methods for studying Fe-S proteins and their assembly, Fluorescent reporters to track Fe-S cluster assembly and transfer reactions, Mechanism-based strategies for structural characterization of radical SAM reaction intermediates, Purification and Characterization of Recalcitrant Cobalamin-Dependent Radical S-adenosylmethionine Methylases, A polymerase with potential: the Fe-S cluster in Human DNA Primase, In Vitro Studies of Cellular Iron-sulfur Cluster Biosynthesis, Trafficking and Transport, and Fe-S cluster Hsp70 Chaperones: the ATPase cycle and protein interactions.

  • Immunity and Inflammation in Health and Disease

    Emerging Roles of Nutraceuticals and Functional Foods in Immune Support
    • 1 Edición
    • Shampa Chatterjee + 2 más
    • Inglés
    Immunity and Inflammation in Health and Disease: Emerging Roles of Nutraceuticals and Functional Foods in Immune Support provides a comprehensive description of the various pathways by which the vertebrate immune system works, the signals that trigger immune response and how fnew and novel nutraceuticals and functional foods, can be used to contain inflammation and also to boost immunity and immune health. Inflammation is a tool to fight pathogens and the vertebrate immune system has a very complex network of cells to achieve this. However inflammation that goes awry is also the leding cause of several diseases ranging from cardiovascular diseases to diabetes. This book covers the entire gamut from the various cellular players in the inflammation-immune response to its ramifications in terms of protection against pathogens as well as in onset of metabolic, aging and auto-immune related diseases. Finally, the balancing role of dietary nutrients between host defence and immune support is also showcased. The first three scetions explain the various components of the immune system and their modes of activation. The fourth section deals with the ramifications of a robust and execessive inflammatory response. The fifth section is focused on the association between nutrition and immunity and how deficiencies in certain nutrients may affect immunocompetence. The sixth section chapters represent a vision of paradigm shifts within the field and discusses possible future directions. This bool will be a valuable reference for researchers studying immune health either in academia, or in the nutraceutical or functional food industries. Product developers in nutraceutical, supplement, functional food, and health food companies will also appreciate the information presented here.

  • FDA Warning Letters About Food Products

    How to Avoid or Respond to Citations
    • 1 Edición
    • Joy Frestedt
    • Inglés
    FDA Warning Letters About Food Products: How to Avoid or Respond to Citations uses examples of FDA warning letters about food products as training tools to discuss important quality and manufacturing issues encountered by food companies around the world as they bring food products into the US market. Focused specifically on FDA warning letters surrounding new dietary ingredients and dietary supplements, the book first introduces FDA warning letters in general. Each chapter then focuses on specific issues identified, including HAACP/quality systems, imports/exports, food contact issues, etc. This book helps the food industry train professional team members (across the spectrum of experience levels) to avoid common issues often cited in warning letters. It serves both as an authoritative reference on the common types of warning letters issued to food companies today, and as a guide to best practices for food manufacturers.

  • Incorporating Cultures' Role in the Food and Agricultural Sciences

    • 1 Edición
    • Florence V. Dunkel
    • Inglés
    Incorporating Cultures' Role in the Food and Agricultural Sciences addresses the practical needs of the professors, administrators and students who often face challenges of working together with Indigenous peoples with whom they have no prior experience. Missed communication, failed projects and unrealistic goals are daily realities. Academia and industry often encounter frustration in recruiting and retaining Native American students and other ethnicities. This text is a guide for anyone working in the food or agriculture disciplines or industries, particularly for those working with people of a culture different from one’s own. Comprehensive, full awareness of one’s own culture is a prerequisite for effective teaching and learning within another culture. This book is replete with stories, examples and peer-refereed journal articles to help build awareness. These stories, examples and articles from multiple voices are placed over a basic underlying framework that is summed up in the title of the book itself.

  • Sterol Regulation of Ion Channels

    • 1 Edición
    • Volumen 80
    • Inglés
    Sterol Regulation of Ion Channels, Volume 80, the latest in the Current Topics in Membranes series provides outstanding content to the scientific community on relevant topics that relate to the broad field of membranes. Topics of note in this new release include Membrane structure and general mechanisms of sterol regulation of ion channels, the Regulation of ion channels by sterols as boundary lipids, the Differential effects of sterols on ion channels: specific vs. non-specific interactions, the Structural determinants of cholesterol-ion channels interactions, and the Regulation of Ca2+-sensitive K+ channels by cholesterol and bile acids via distinct channel subunits and sites, amongst other specialized chapters. The serial is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes

  • Comparative Anatomy and Histology

    A Mouse, Rat, and Human Atlas
    • 2 Edición
    • Piper M. Treuting + 2 más
    • Inglés
    The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease.

  • Methods in Tau Cell Biology

    • 1 Edición
    • Volumen 141
    • Inglés
    Methods in Tau Cell Biology, Volume 141, the latest release in the Methods in Cell Biology series, looks at methods involved in tau cell biology. Edited by leaders in the field, this volume provides proven, state-of-art techniques and relevant historical background and theory that aids researchers with tactics for efficient design and effective implementation of experimental methodologies. Topics of note in this updated volume include sections on Recombinant tau expression and purification, In vitro MT dynamics and MT ends, Methods related to investigating tau structure and MT bundling, Neurite outgrowth and retraction, and Methods related to studying tau fragmentation.

  • The Complex Connection between Cannabis and Schizophrenia

    • 1 Edición
    • Michael T. Compton + 1 más
    • Inglés
    The Complex Connection between Cannabis and Schizophrenia provides an in-depth overview of the current state of research into the role that cannabis plays in schizophrenia, covering both the pathophysiological and the pharmacological implications. It addresses the epidemiology of cannabis use and the risks associated with its use, the biological aspects of the drug, its effects on the brain and the pharmacological possibilities of using cannabidiol to treat schizophrenia. It is the only book on the market devoted exclusively to examining the links between this very commonly used (and misused) drug and a specific set of devastating psychiatric illnesses, providing a comprehensive guide to our current understandings of this relationship. Marijuana is the most commonly used illicit drug globally, and is becoming increasingly decriminalized and even legalized worldwide. Among the numerous mental-health concerns related to the drug, there is mounting evidence of an intricate link between cannabis use and schizophrenia and related psychotic disorders. At the same time, there is promising evidence to suggest that cannabidiol, one of the many compounds found in cannabis that activates the brain’s cannabinoid receptors, could prove to be an effective antipsychotic to treat schizophrenia.

  • Insect Epigenetics

    • 1 Edición
    • Volumen 53
    • Inglés
    Insect Epigenetics, Volume 53 provides readers with the latest interdisciplinary reviews on the topic. Updated chapters in this new release include Epigenetics in insects: Mechanisms, ecological outcomes, and evolutionary consequences, Nutrition and epigenetic change in insects, microRNAs in Drosophila insulin regulation, Epigenetic regulation of longevity in insects, Epigenetic influences on diapause, the Impact of parasites on epigenetics of their insect hosts, The molecular physiology of locust swarming behavior, The future of environmental epigenetics: insights using the clonal water-flea model, and. Epigenetics – A hidden target of insecticides. Led by volume editor Heleen Verlinden, this is an essential reference source for entomologists, zoologists, geneticists and insect chemists.

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