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Elsevier

Libros en Ciencias de la Vida

  • The Roadmap of Research

    A Guide to Understanding and Writing a Medical Study
    • 1 Edición
    • Vincenzo Giordano + 3 más
    • Inglés
    The Roadmap of Research: A Guide to Understanding and Writing a Medical Study helps readers easily grasp the context, methodologies, findings, and implications of research studies, build on previous work, avoid redundancies, and identify areas where new studies can contribute significantly. The book enables researchers to innovate, propose new ideas, and design studies that contribute novel perspectives or methodologies to the field. Each step in this roadmap plays a pivotal role in the research process, from building a foundation of knowledge through reading and understanding, to generating new ideas through critical thinking, and finally, disseminating findings through clear and effective writing.

  • Histone Deacetylases in Neurodegenerative Disease Part B

    • 1 Edición
    • Volumen 734
    • Inglés
    Histone Deacetylases in Neurodegenerative Disease, Part B, Volume 734 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on timely topics surrounding the Interaction of HDAC6 ZnF UBP with Tau affects its stability by NMR and Simulation studies, Protocols for In Vitro Analysis of Liquid-Liquid Phase Separation of Proteins, Histone deacetylases in NS, Histone Deacetylase 6 ZnF UBP domain enhances podosome formation in neuronal cells studied by high-resolution confocal microscopy, Methodological approach to Investigate Peroxiredoxin 1 Deacetylation by Histone Deacetylase 6, Critical structural features of HDAC11 inhibitors, and much more.Additional chapters in this release include Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration, Elucidation of Site-Specific Ubiquitination on Chaperones in Response to Mutant Huntingtin, Protein acetylation dynamics (histone and non-histone) and role protein deacetylases in disease, Epigenetic Clues: Predicting Maternal Depression Through DNA Methylation, A short guide on in vivo transfection of flag-HDAC4 in dentate gyrus for study of adult neurogenesis in brain trauma, Decoding the Acetylation Journey from Neural Crest to Melanocyte, and more.

  • Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

    Part A
    • 1 Edición
    • Volumen 169
    • Inglés
    Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications, Volume 169 in the Advances in Immunology series, presents an authoritative exploration on how microbial communities contribute to the initiation, progression, and treatment of head and neck cancers. Chapters highlight The Microbiome of the Head and Neck Region, Overview Head and Neck Microbiota and the Factors Influencing the Head and Neck Microbiome, Mechanistic Pathways of Dysbiosis in Cancer Development, Oral Microbiota and OPMDs, Oral Potentially Malignant Disorders (OPMDs): An Overview, Oral Microbiota and Oral Cancer, Oral Squamous Cell Carcinoma (OSCC): An Overview, and much more.Additional chapters cover the Role of the Oral Microbiome in Oral Cancer (OSCC), Microbiome as a Prognostic Indicator in Oral Cancer, Diagnostic and Therapeutic Applications, Microbiome-Based Diagnostic Approaches, Modulating the Head and Neck Microbiome for Cancer Prevention, Microbiome-Targeted Therapeutics in Head and Neck Cancer, Artificial Intelligence in Microbiome Data Analysis: Applications in Head and Neck Cancer, and Challenges and Future Directions in Head & Neck Microbiome Research.

  • Radiation Spectrum and Plant Metabolism

    Interactions from the Subcellular to the Ecosystem Level
    • 1 Edición
    • Sumira Jan + 1 más
    • Inglés
    Radiation Spectrum and Plant Metabolism brings together advances in photobiology, biophysics, and metabolite chemistry to illuminate how light shapes plant structure, function, and ecological performance. The volume follows the pathways through which radiation interacts with plant systems, offering an integrated perspective that links subcellular processes to whole‑plant behavior and ecosystem dynamics.Covering the full breadth of plant–light relationships, the book examines the optical properties of leaf tissues, the coordination of photoreceptors and pigments, and the metabolic networks through which plants interpret spectral cues. It outlines how shifts in light quality influence development, stress responses, and the production of secondary metabolites, providing a mechanistic foundation for understanding plant adaptability under both natural and controlled environments.As climate change alters terrestrial and cosmic radiation patterns, a comprehensive view of plant responses has become increasingly critical. This reference resource synthesizes emerging insights into changing spectral regimes, their biochemical and physiological consequences, and the broader implications for plant fitness, crop resilience, and phyllosphere interactions. Later chapters connect these concepts to applied practice, highlighting innovations in horticultural lighting technologies and the measurement techniques that support precision light management.Designed for researchers and advanced practitioners across the plant sciences, this volume offers a rigorous framework for interpreting how variable radiation environments shape biological systems and the metabolic processes that sustain them.

  • Human Microbiome and their Implications for Oncological Diagnosis and Treatment

    A Handbook for Clinicians and Researchers
    • 1 Edición
    • Mohammad Akram
    • Inglés
    Human Microbiome and their Implications for Oncological Diagnosis and Treatment; A Handbook for Clinicians and Researchers explores the crucial role of the human microbiome in oncology. The book aims to provide a thorough understanding of microbiome-oncology interactions by compiling diverse perspectives and insights into existing research findings and methodologies. It addresses the need for a comprehensive educational resource tailored to the needs of clinicians and researchers. Contributed by leading experts, it examines the multifaceted roles, diagnostic potential, and therapeutic implications of the microbiome in cancer.Readers will find an in-depth look at microbiome-oncology interactions, addressing microbial dysbiosis, diagnostic biomarkers, therapeutic interventions, and emerging research trends. The handbook provides practical insights, clinical guidelines, and fosters interdisciplinary collaboration to advance the field of oncology to clinicians, researchers, educators, and students seeking up-to-date information on the role of the human microbiome in cancer.

  • Brain Energy Metabolism in Alzheimers Disease - Part C

    • 1 Edición
    • Volumen 188
    • Inglés
    Brain Energy Metabolism in Alzheimer’s Disease – Part C, Volume 188 in the International Review of Neurobiology series, presents the latest research on metabolic dysfunction and its role in neurodegenerative diseases. This volume brings together contributions from an international panel of experts, exploring the molecular, cellular, and systemic aspects of energy metabolism in Alzheimer’s disease and related disorders.Chapters in this release examine metabolic therapeutic targets in Alzheimer’s disease, alterations in brain energy metabolism in comparison with Parkinson’s disease, and the role of epigenetic modulation through natural compounds. Additional sections address mitochondrial dysfunction, disruption of metabolic pathways, and the contribution of glial cells to neurodegenerative processes.Further contributions explore metabolic disorders linked to Parkinson’s disease, signaling pathways in neurodegeneration, and advances in therapeutic and diagnostic strategies targeting key enzymes. The volume also highlights the role of intestinal microbiota, nanocarrier-based therapeutic approaches, and emerging treatments such as HDAC inhibitors. Together, these chapters provide a comprehensive overview of the mechanisms, biomarkers, and therapeutic prospects related to energy metabolism in neurodegenerative diseases, making this volume an essential reference for researchers and clinicians in neuroscience and neurobiology.

  • Autophagy – Part B

    • 1 Edición
    • Volumen 404
    • Inglés
    Autophagy, Part B, Volume 404 provides an in-depth exploration of advanced mechanisms, functions, and roles of autophagy in health and disease. This volume features contributions from leading experts, covering recent developments in autophagy research, its implications in cellular homeostasis, neurodegeneration, cancer, immunity, and therapeutic strategies. Chapters in this new release include From autophagy to mitophagy: Quality control mechanisms in skeletal muscle, Impact of Different Exercise Modalities on Mitophagy in Human Skeletal Muscle, Eat, Heal, Repeat: How Zebrafish Master Regeneration, Pathophysiology, biological models and new therapeutic approaches in β-Propeller Associated Neurodegeneration, and more.Additional sections discuss Autophagy in adipose tissue thermogenic function and Non-selective and selective autophagy as mediators of mechanical forcest. Designed for researchers, clinicians, and students, the book offers valuable insights into the complexities and applications of autophagy in modern biomedical science.

  • Artificial Intelligence for Enhanced Diagnosis in Oncology

    • 1 Edición
    • Gowhar Rashid + 3 más
    • Inglés
    “Artificial Intelligence for Enhanced Diagnosis in Oncology” explores the transformative role of AI in cancer care, examining its applications across various domains. The book introduces key AI technologies, such as machine learning and natural language processing, and discusses the challenges and opportunities they present in oncology. Each chapter focuses on specific areas where AI has significant impact, including early cancer screening, diagnosis, pathology, surgical oncology, and imaging. Readers will learn how AI improves precision in treatment, optimizes clinical trial designs, and accelerates drug discovery while addressing critical issues like predicting adverse drug reactions and assessing cancer risks. Emphasizing personalized oncology, the book also highlights innovative approaches to patient education and engagement. Concluding with insights on emerging trends and ethical considerations, this resource is essential for researchers, clinicians, and healthcare professionals committed to advancing cancer care through AI technologies.

  • AI and Data Science in Precision Medicine, Predictive Analytics, and Medical Practice

    • 1 Edición
    • Olfa Boubaker + 1 más
    • Inglés
    AI and Data Science in Precision Medicine, Predictive Analytics, and Medical Practice examines the transformative role of AI and data science in improving diagnosis, treatment, and healthcare delivery. It shows how machine learning, deep learning, and advanced signal and image analysis enable breakthroughs in genomics, multi-omics integration, biomedical imaging, EEG-based seizure prediction, and real-time physiological monitoring. The book highlights AI-driven stratification of complex syndromes such as sepsis, stroke, and acute respiratory distress syndrome, demonstrating how data-driven models support early detection, personalized interventions, and actionable clinical decisions.The volume also presents system-level innovations, including AI-based forecasting for dialysis, blood supply management, and telemedicine optimization. It addresses ethical and regulatory challenges, fairness, transparency, data governance, and clinical validation, providing a practical roadmap for healthcare professionals, engineers, researchers, and policymakers. By integrating responsible, human-centered AI into precision medicine, the book illustrates clear pathways to enhance patient care, improve outcomes, and promote equitable healthcare.

  • Music and Sleep

    A Scientific Perspective
    • 1 Edición
    • Kira Vibe Jespersen + 1 más
    • Inglés
    Music and Sleep: A Scientific Perspective presents a comprehensive discussion on the topic of music and sleep. The book brings these disciplines together, providing a solid background, recent developments, and a deeper understanding of their synthesis. Of special interest are technical advances that have made sleep recordings, music manipulation, and sleep stimulation more accessible in recent years. Notably, sleep disturbances are an increasing problem in society, highlighting the importance of developing low-risk and cost-effective treatments. Healthcare professionals looking to integrate novel information on music and sleep to increase their patients' wellbeing need look no further than this book.Music is widely used as sleep aid, but the exact neural mechanisms of the sleep-enhancing function of music are not fully clear. New research output includes exciting breakthroughs, hypotheses, and discoveries in both of these areas. However, since research fields on the neuroscientific mechanisms of music and those of sleep have not traditionally overlapped, this book fills in the gaps.

  • Cell Death Part B

    • 1 Edición
    • Volumen 206
    • Inglés
    Cell Death Part B continues the comprehensive exploration of cellular mechanisms governing the fate of cells in health and disease. This volume delves deeper into the molecular pathways, regulatory networks, and biological consequences of various cell death modalities, including apoptosis, necrosis, autophagy, ferroptosis, pyroptosis, and other emerging forms.

  • Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications

    • 1 Edición
    • Arun Kumar + 2 más
    • Inglés
    Extracellular Vesicle-Based Biovectors for Diagnostic and Biomedical Applications provides comprehensive coverage on not only the biosynthesis, isolation, purification, and functionalization of extracellular vesicles for therapeutic and diagnostic applications, but also current trends in functionalized extracellular vesicles for biomedical research and commercial-scale opportunities. Sections focus on the fundamental aspects of extracellular vesicles, covering their origin, classification, biosynthesis, isolation techniques, purification challenges, and functionalization for biomedical applications, while also delving into the therapeutic applications of extracellular vesicles and their role in treating diseases.Content also address biocompatibility, safety, translation challenges, biocompatibility, and translation challenges. Final sections explore the diagnostic potential of extracellular vesicles in biomedical research, highlighting their role as diagnostic biomarkers in various diseases. Emerging technologies and future directions in extracellular vesicle research round out the content, making it a valuable reference for researchers and clinicians seeking an in-depth understanding of extracellular vesicles and their potential biomedical applications.

  • Structural Studies of Amyloid-Forming Peptides

    • 1 Edición
    • Volumen 729
    • Inglés
    Structural Study of Amyloid-β, Volume 729 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on important topics such as the Extraction of Amyloids from Neurodegenerative Disease Tissues for Structural Analysis, Cryo-EM Structure Determination of Amyloid Fibrils: Methodology, Insights, and Practical Tools, Methods for studying molecular architecture of Ab aggregates in tissues using cryo-ET, Cryo-EM methods to study binding between amyloid fibrils and chemical compounds or ligan, Dynamics studies of side-chains and hydration shells in amyloid-beta fibrils using deuterium and oxygen-17 solid-state NMR, and much more.Additional chapters cover the Technical aspects of pressure jump NMR applied to the study of Abeta and protein oligomerization, Characterizations of the beta-amyloid-membran... interaction intermediates, Time-resolved solid-state NMR studies of oligomer formation, Methods for characterizing the individual filament structures of amyloid peptide assemblies using atomic force microscopy, Single-molecule fluorescence spectroscopy and imaging on heterogeneous amyloid beta aggregation, Two-dimensional FT-IR methods on amyloid aggregation and folding pathways, and much more.

  • AI and Data Science in Medical Research

    • 1 Edición
    • Olfa Boubaker
    • Inglés
    AI and Data Science in Medical Research focuses on the integration of AI and data science into medical research, highlighting their impact on drug discovery, medical imaging, diagnostics, and genomic medicine. The book addresses the acceleration of therapeutic compound discovery and optimization of drug development pipelines through AI. The volume also discusses advancements in medical imaging, including early disease detection and neuroimaging. Additionally, it covers the application of AI in genomic medicine, offering insights into personalized treatment strategies.The volume concludes with an examination of AI's role in public health surveillance, particularly in disease detection and epidemiological research.

  • Artificial Intelligence Applications in Emerging Healthcare Technologies

    • 1 Edición
    • Miguel Antonio Wister Ovando + 2 más
    • Inglés
    Artificial Intelligence Applications in Emerging Healthcare Technologies presents the latest advances and state-of-the-art methods and applications of computer science and emerging AI technologies in health and medicine. The book explores the impact of artificial intelligence (AI) in healthcare for medical decision-making and data analysis, tackling topics such as cloud computing, cybersecurity, the internet of things, natural language processing, virtual health, data science applied to healthcare, personalized medicine, imaging, diagnosis, drug discovery, and diseases, among others.Chapters present adaptations or improvements on previous models and algorithms to process data from different sources. Other chapters investigate new formulations for the optimization of known procedures and algorithms. Finally, all chapters use experimental methods to study problems of interest in healthcare. This is a great resource for researchers and students who want to learn how machine learning algorithms and other data science techniques have been implemented to solve healthcare-related problems.

  • Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease

    • 1 Edición
    • Zahra Keshavarz Motamed + 2 más
    • Inglés
    Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease explains how abnormal hemodynamics (blood flow dynamics) greatly alter the cardiovascular system’s ability to transport, control and maintain blood flow throughout the body. These deviations often lead to the initiation and progression of disease. Notably, hemodynamic quantification can be extremely useful for accurate and early diagnosis of cardiovascular disease. Particularly, the ability to monitor and predict hemodynamic effects following specific interventions can significantly broaden lifesaving options. However, image-based computational modelling of predictive hemodynamics analysis methods (and therefore new diagnostic tools) are rare. By extending quantitative methods of analysis, medical professionals can foresee effects of various cardiovascular interventions, allowing for optimized, situation-based care.Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease posits that novel, image-based computational modelling hemodynamic analysis tools will enable the next generation of diagnosis, predictive, and treatment planning resources for cardiovascular disease. Readers will become well-versed in recent advances in hemodynamic approaches, while preparing themselves for the next wave of revolutions in cardiovascular health.

  • Sustainable Cropping Systems Under a Changing Climate

    • 1 Edición
    • Mukhtar Ahmed
    • Inglés
    Sustainable Cropping Systems Under a Changing Climate explores how climate change is reshaping agriculture and highlights the urgent need for resilient, adaptive, and sustainable farming practices. As extreme weather, rising temperatures, and resource pressures threaten food security, this volume offers practical pathways to transform agricultural systems.Bringing together leading research, real-world case studies, and innovative strategies, this book addresses vulnerabilities and opportunities in modern farming. It covers sustainability principles, climate-smart practices, and the roles of soil health, biodiversity, conservation agriculture, organic farming, agroforestry, regenerative approaches, and plant–microbe interactions in enhancing resilience. Special focus is given to intensive systems such as rice–wheat and rainfed agriculture, particularly in the Global South.With an interdisciplinary approach and emphasis on both scientific evidence and practical application, this volume bridges a critical gap by supporting informed decision-making at farm, institutional, and policy levels. It is a timely resource for researchers, agronomists, extension professionals, and others seeking to future-proof agriculture through nature-based and technological solutions for climate adaptation and mitigation.

  • Vaccinology and Immunizations

    • 1 Edición
    • Jahangir Moini + 2 más
    • Inglés
    Vaccinology and Immunizations is a thorough resource on the immune system, the history of vaccines, vaccine preparation, the process of vaccine approval, and the prevention and eradication of diseases. It also includes chapters on vaccine safety and errors, and complete information on pediatric and adult immunizations. There is also discussion on elderly immunology and immunization for people who are seeking to travel abroad, as well as timely information about COVID-19.Its focus on the innate and adaptive defense systems of the body will ensure understanding of human immunity and how immunizations are effective. There is a variety of available titles related to vaccinology and immunizations, but many are now outdated.Vaccinology and Immunizations provides a new, updated resource that is widely needed, and will be welcomed by students of undergraduate, graduate and master level in vaccinology or immunology, and would also be of interest to nurses, researchers, and pharmacists.

  • Role of Microbes in Ecosystem Processes and Environmental Management

    • 1 Edición
    • Ritu Mishra + 3 más
    • Inglés
    Role of Microbes in Ecosystem Processes and Environmental Management explores microbial ecology and its impact on ecosystem processes while also highlighting the latest advancements in the application of microbes in environmental management and other industries. The book provides an overview of microbes in their natural environments, covering their role in soil health, carbon cycling, waste degradation, and plant-microbe interactions. It discusses the influence of microbes on weathering, erosion, and climate change, as well as their crucial role in ecosystem regulation and the restoration of degraded ecosystems. Sections also focus on the utilization of microbes in environmental management strategies as biocontrol agents and biological indicators of pollution and water quality and explore the practical applications of microbes in environmental bioremediation and for advanced microbial technologies in agriculture practices, food industries, energy production, mining, and healthcare. This is a comprehensive resource for researchers, faculty, postgraduate students, and industry professionals with a keen interest in microbial ecology and microbial-based product development.

  • Active Food Packaging

    Principles, Technologies and Innovations
    • 1 Edición
    • Swarna Jaiswal + 2 más
    • Inglés
    Active Food Packaging: Principles, Technologies and Innovations, a volume in the Sustainable Food Packaging series, is a comprehensive guide to the latest developments in active packaging for food products. This book provides an overview of active packaging and its various types, advantages, and challenges, as well as a detailed analysis of different active packaging technologies such as oxygen scavengers, antimicrobial agents, moisture absorbers, and ethylene absorbers. It also covers the latest innovations and applications of active food packaging, including intelligent active packaging, shelf-life extension, food safety and quality control, sustainability, waste reduction, and nanotechnology.With the growing importance of sustainability and increasing demand for understanding the complex principles and technologies involved in active food packaging, this series of books represents a comprehensive guide to navigating this rapidly evolving landscape.

  • Next-Gen Smart Farming

    Integrating AI, IoT, Digital Twin, and Robotics for Cyber-Physical Systems
    • 1 Edición
    • Annamaria Castrignanò + 3 más
    • Inglés
    Next-Gen Smart Farming presents a thorough, evidence-based assessment of using emerging physical and computerized systems designed to enhance agricultural efficiency. It balances demonstrated benefits with a clear articulation of potential risks.The work surveys the entire pipeline, from sensing technologies and data collection to artificial intelligence and machine learning, spatial analysis, decision modeling, and automation. It highlights how these technologies can strengthen crop monitoring, yield forecasting, and farm management, while it also examines governance, equity, and ethical considerations essential for responsible deployment. Economic, environmental, and social impacts are analyzed, providing a comprehensive framework for evaluating trade-offs and outcomes in real-world contexts.Framed as an interdisciplinary resource, the volume equips researchers, industry practitioners, extension specialists, and policymakers with practical methodologies, metrics, and narratives needed to implement scalable digital agriculture solutions that improve productivity, resilience, and sustainability across diverse real-world settings.

  • Oral Cancer and Artificial Intelligence

    Transforming Diagnosis, Treatment, and Research
    • 1 Edición
    • Sujata Dash + 4 más
    • Inglés
    Oral Cancer and Artificial Intelligence: Transforming Diagnosis, Treatment, and Research explores the intersection of artificial intelligence (AI) and oral cancer care. Sections detail how AI technologies are revolutionizing and evolving diagnosis, treatment, and management, offering new hope and improved outcomes for patients. The book is structured into ten well-defined sections, each addressing a critical aspect of oral cancer care enhanced by AI. It features contributions from leading experts in the fields of AI, oral cancer research, biomedical engineering, and clinical practice from prestigious, worldwide institutions who share valuable insights and their experiences in applying AI to transform oral cancer care. This book is an essential resource for researchers, clinicians, healthcare professionals, and students interested in the transformative potential of AI in oral cancer care. It offers a blend of theoretical knowledge, practical applications, and future directions, making it a comprehensive guide to understanding and leveraging AI to improve outcomes in oral cancer management.

  • Red Wine Technology

    • 2 Edición
    • Antonio Morata
    • Inglés
    Back in its second edition, Red Wine Technology, Second Edition continues to offer a solutions-based approach to the challenges associated with red wine production. It focuses on the technology and biotechnology of red wines and is ideal for anyone in need of a succinct reference on novel ways to increase and improve overall red wine production and innovation. This updated edition provides emerging trends in modern enology, including molecular tools for wine quality and analysis. In addition to updating existing topics, it is expanded to include a variety of completely new chapters on cutting-edge topics such as the red wine microbiome, the use of viruses in wine biotechnology, smoke taint, the future of yeast research, and environmental winery management for climate change. Red Wine Technology, Second Edition is an essential resource for wine producers, researchers, practitioners, technologists and students.

  • Approaches for Brain Targeting Using Nanoparticulate Systems

    • 1 Edición
    • Bhagyashree V. Salvi + 2 más
    • Inglés
    Approaches for Brain Targeting Using Nanoparticulate Systems aims to explore variety of nanoparticulate systems in the enhancement of therapeutic delivery, promotion for effective brain targeting, and reduction in the off-targets. Presenting the latest research, this book offers comprehensive insight into various nanosystems designed to overcome the blood brain barrier. This book presents the latest research on targeting approaches, physicochemical characteristics of nanoparticles, and the role of nanoparticles in enhancing the permeation of therapeutic systems across the blood brain barrier. Readers will also be able to develop a deeper understanding of how nanotherapeutics can revolutionize brain targeting through clinical applications.

  • Cerebellum Development and Disease

    • 1 Edición
    • Volumen 167
    • Inglés
    Cerebellum Development and Disease, Volume 167 offers a comprehensive overview of the intricate processes underlying the formation, maturation, and function of the cerebellum, as well as the wide spectrum of disorders that can affect this essential brain region. Chapters in this new release cover Olivocerebellar circuit development as a substrate for dystonia pathogenesis, Simply complex – that structure of the cerebellar neuronal lineage, Ontogenesis and diversification of cerebellar glia: a developmental perspective, Purkinje cell diversification: a blueprint for cerebellar development, patterning, and evolution, On the Emergence of Folding in the Cerebellum, Scaling and regeneration in the developing cerebellum, ASTN2 in ASD and Neurodevelopmental Disorders, and much more.Additional sections focus on Stem cell-derived in vitro models of human cerebellar development, Development of Spinocerebellar System within the Precerebellar Network, and Cerebellum evo-devo. The book brings together leading experts in neurodevelopment, neurobiology, genetics, and clinical neurosciences to explore the molecular and cellular mechanisms guiding cerebellar development, from embryogenesis to adulthood.

  • Magnetic Resonance Fingerprinting for Quantitative MRI

    • 1 Edición
    • Volumen 14
    • Dan Ma + 2 más
    • Inglés
    MR Fingerprinting is emerging as a clinically feasible and versatile tool for quantitative MR imaging. Magnetic Resonance Fingerprinting for Quantitative MRI focuses on all aspects of MR Fingerprinting techniques and applications. Presenting a detailed and clear description of the technology, implementation, clinical translation issues and applications, it emphasizes different perspectives of MR signals and their utilization, with the goal of inspiring readers to explore new MR Fingerprinting designs. The book starts each section with a discussion on rethinking the MR acquisition and the opportunities provided by, for example, different MR contrast mechanisms, signal modeling, post-processing and clinical applications.Magneti... Resonance Fingerprinting for Quantitative MRI is a complete reference for magnetic resonance imaging researchers and radiologists.

  • Nanoscience and Nano-Formulations for Sustainable Vegetable Crop Production

    • 1 Edición
    • Azamal Husen
    • Inglés
    Nanoscience and Nano-Formulations for Sustainable Vegetable Crop Production offers a comprehensive overview of the latest advances in nanotechnology to enhance yield, nutritional value, and delivery efficiency in vegetable crops, particularly those with shorter growth cycles.Although nanoscience is already deeply embedded in global food production, especially in cereals and grains, its targeted application in olericulture holds significant potential for strengthening global food security. Effective implementation, however, demands a clear understanding of nanoparticles’ behavior and interactions with plants, ensuring technological progress aligns with safety standards and consumer confidence. This book covers innovations in several key areas of vegetable farming, including nanofertilizers, nanopesticides, and nano-packaging materials, spanning the entire continuum—from seed priming to postharvest management, while also addressing practical dimensions of scalability, farmer adoption, and system integration.Designed for researchers, scientists, and advanced-level students, this resource will serve as a valuable reference for harmonizing productivity, resilience, and sustainability in modern vegetable production.

  • Nano-Delivering Plant Biostimulants and Anti-Pathogenic Agents

    • 1 Edición
    • Jen-Tsung Chen
    • Inglés
    Nano-Delivering Plant Biostimulants and Anti-Pathogenic Agents examines the role of nanotechnology in strengthening plant disease resilience. The book examines the development and application of engineered nanoparticles (NPs) in plant protection, emphasizing their capacity to boost plant immunity and target specific pathogens. It also covers the latest breakthroughs in nanoparticle synthesis, characterization, and mechanisms of action in plant–pathogen interactions.The text further explores the integration of nanoparticles with biostimulants, including plant growth regulators (PGRs) and growth-promoting microorganisms (PGPMs), as well as the emerging use of nanobiofertilizers. It emphasizes how these advanced nanodelivery systems can optimize the efficiency of plant disease management strategies, including pest control and antimicrobial delivery.Finally, the volume addresses key topics such as the use of silver, metalloid, and carbon nanomaterials for disease prevention and plant protection. It also delves into the regulatory and ethical considerations surrounding nano-agrobiotechnolo... offering critical insights into its safe and sustainable application. This book serves as an essential resource for those exploring innovative, nanotechnology-drive... solutions in agriculture.

  • Biological Processes in the Food Industry

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari + 1 más
    • Inglés
    Biological Processes in the Food Industry, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for biological production of different food ingredients and nutraceuticals including upstream and downstream techniques. These processes and unit operations are very important in the manufacture of products such as enzymes, colouring pigments, vitamins, microbial lipids and proteins. Divided in three sections, “Basics of food biological processes”, “Biological processing operations”, and “Application of biological processes in the food industry”, all chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment to biological unit operations. Written by experts in the field of food engineering, in a simple and dynamic way, this book targets industrial Engineers working in the field of food processing and within food factories to make them more familiar with the food processing operations and equipment.

  • Inflammation and Cancer

    Mechanisms, Diagnosis, and Therapeutic Strategies
    • 1 Edición
    • Anoop Kumar + 4 más
    • Inglés
    Inflammation and Cancer: Mechanisms, Diagnosis, and Therapeutic Strategies delves into the intricate relationship between inflammation and cancer, a crucial area of contemporary biomedical research. Sections provide an overview of inflammation's role in cancer, discussing molecular connections and signaling pathways. Chapters explore inflammatory pathways in various cancers, including breast, oral, lung, prostate, skin, and gastrointestinal cancers. The book also covers tumorigenesis, metastasis, preventive strategies, inflammatory biomarkers for cancer diagnosis, and innovative therapeutic designs. Final chapters focus on the dual role of platelets, targeting tumor-associated macrophages, novel treatment approaches, and recent advances in the field.This title offers substantial benefits to researchers, clinicians, and healthcare professionals by providing a thorough understanding of the cellular and molecular pathways linking inflammation and cancer, aiding in the development of effective anti-cancer immunotherapies. By highlighting the latest research and potential therapeutic strategies, this book serves as an essential resource for anyone dedicated to combating cancer through innovative and informed immunotherapeutic approaches.

  • Equity, Diversity and Inclusion

    Sisyphean Undertaking to an Achievable Reality
    • 1 Edición
    • Faisal Khosa
    • Inglés
    Equity, Diversity and Inclusion: Sisyphean Undertaking to an Achievable Reality explores critical themes across diverse academic disciplines, including business, education, engineering, graduate medical education, health sciences, law, medicine, pharmacy, psychology, public health, and veterinary. Each chapter traces the evolution of its respective discipline, examining how landmark social movements, civil rights milestones, and legislative reforms have shaped the discourse on equity. Alongside these histories, authors introduce key theoretical frameworks that illuminate the concept of intersectionality.Th... book also confronts contemporary challenges head-on. From systemic discrimination and racial profiling to gender inequality and barriers to social and economic mobility, the chapters candidly address the obstacles faced by marginalized groups. More importantly, this volume moves from identifying problems to driving solutions: it offers practical strategies and evidence-based best practices for cultivating equity, diversity, and inclusion (EDI) in workplaces, educational institutions, and communities. Ultimately, it invites readers to embrace the journey toward a more just and inclusive society. It reminds us that while the challenges may be great, the transformation begins with everyone taking that first step.

  • AI-Driven Human-Machine Interaction for Biomedical Engineering

    Concepts, Applications, and Methodologies
    • 1 Edición
    • Kapil Gupta + 4 más
    • Inglés
    AI-Driven Human-Machine Interaction for Biomedical Engineering: Concepts, Applications, and Methodologies offers a comprehensive examination of the intricate relationship between humans and machines, particularly through the transformative lens of artificial intelligence (AI). As AI technologies rapidly evolve, understanding their implications for human-machine interaction (HMI) has become essential across various domains, especially healthcare. Structured into well-defined chapters, the book begins with an introduction to AI-driven HMI, laying the groundwork for understanding its significance in sustainable healthcare and beyond. Subsequent chapters explore critical topics such as machine learning principles, advanced biomedical data classification methods, and the role of AI in telemedicine.Readers will delve into cutting-edge techniques, from deep learning to non-invasive computer vision, while also examining the implications of these technologies across industries. Each chapter equips readers with actionable insights and highlights emerging trends, ethical considerations, and the future of AI in HMI, ensuring a well-rounded perspective on this dynamic field. This is an invaluable resource for researchers, academics, and students in the fields of Biomedical Engineering, Computer Science, Data Science, Artificial Intelligence, and Healthcare Technology.

  • Immunity to Immunotherapy in Cancer

    Mechanisms and Limitations
    • 1 Edición
    • Mukesh Nandave + 1 más
    • Inglés
    Immunity to Immunotherapy in Cancer: Mechanisms and Limitations explores the intricate interplay between cancer therapy and the immune system, addressing why some patients do not respond to immunotherapy and scientific solutions in development. The book examines molecular strategies of immune evasion within the tumor microenvironment, providing insights into factors like tumor heterogeneity and immune checkpoint mechanisms that contribute to resistance. Highlighting promising approaches such as combination therapies, personalized medicine, and novel immunotherapeutic agents, the book aims to enhance patient outcomes and advance cancer immunotherapy.Design... as a comprehensive guide for professionals and researchers, this textbook offers an overview of the latest scientific discoveries and practical applications in cancer therapy. It serves as an invaluable resource for scientists, doctors, academicians, and students, presenting a path toward more effective, non-toxic, and customized cancer treatments. This book is essential for anyone interested in the future of cancer therapy.

  • Redefining Global Health in the 21st Century

    • 1 Edición
    • Michael John Alistair Reid + 1 más
    • Inglés
    Redefining Global Health in the 21st Century explores the evolving landscape of global health as the world approaches the conclusion of the Sustainable Development Goals (SDG) era. This comprehensive book examines strides made in global health while emphasizing the urgent need to address emerging and persistent challenges. Topics include shifting patterns of diseases, demographic changes, and the evolving nature of health financing, both internationally and domestically. By providing a thoughtful analysis of these issues, the book equips readers with the insights necessary to navigate the future of global health and contribute to ongoing progress in the field.The book also delves into the importance of decolonization in global health initiatives and the adoption of sustainable, inclusive development models. It serves as a valuable resource for students, policymakers, and stakeholders, guiding future research and policy decisions.

  • Cybersecurity for Healthcare Systems in the Internet of Medical Things Era

    • 1 Edición
    • Janmenjoy Nayak + 2 más
    • Inglés
    Cybersecurity for Healthcare Systems in the Internet of Medical Things Era is driven by the imperative to address the intricate convergence of healthcare, technology, and security. In response to the burgeoning challenges presented by the Internet of Medical Things (IoMT), this book is designed to be an indispensable resource for computer systems experts, healthcare staff, and executives. It goes beyond the surface, offering strategic insights and actionable strategies that encompass not only the IoMT landscape but also the intersection of artificial intelligence, signal processing, and cyber security. Cybersecurity for Healthcare Systems in the IoMT Era serves as a problem-solving compass for a diverse readership in the healthcare landscape. For healthcare professionals and IT leaders, the book untangles the complexities of integrating and securing Internet of Medical Things (IoMT) devices, offering a roadmap for understanding and navigating this rapidly evolving terrain. Biomedical engineers, burdened with strategic and everyday decisions, find in this book strategic insights and actionable strategies, empowering them to make informed choices amidst the ever-changing challenges posed by technology and cybersecurity threats. The authors present a comprehensive guide that not only elucidates the challenges and opportunities presented by IoMT but also explores how the synergy of AI and signal processing can elevate healthcare systems. This integration is crucial in deciphering the intricate nuances of medical data, enhancing diagnostics, and fortifying the security of interconnected healthcare networks.

  • Biophysics of Tissue Self-Organization in Morphogenesis

    The Role of Dynamics Along the Biointerface
    • 1 Edición
    • Ivana Pajic-Lijakovic
    • Inglés
    Biophysics of Tissue Self-Organization in Morphogenesis: The Role of Dynamics Along the Biointerface delves into the interactions between tissue and the extracellular matrix. It explores the fundamentals of cell self-rearrangement and the interrelation between biological mechanisms and physical principles responsible for tissue self-organization. The book examines modeling approaches to tissue self-organization and the application of engineering principles to solve medical problems. It also discusses tools, applications, and medical implications, particularly in embryo development, wound healing, and cancerous diseases, concluding with future developments.Coverin... subcellular to supracellular levels, this book is an interdisciplinary guide for researchers in cell biology, biophysics, developmental biology, and more.

  • Multimodal Data Fusion in Healthcare

    AI Approaches for Precision Diagnosis
    • 1 Edición
    • Akansha Singh + 3 más
    • Inglés
    Multimodal Data Fusion in Healthcare: AI Approaches for Precision Diagnosis explores the transformative potential of AI in modern medicine by integrating diverse data sources such as medical imaging, genomics, EHRs, and wearable sensors. It highlights how AI technologies are revolutionizing healthcare systems through personalized and proactive diagnostics. The book covers cutting-edge methodologies, real-world applications, and the challenges of multimodal data fusion. Topics include AI-driven diagnostics, precision medicine, real-time patient monitoring, and the integration of clinical, genomic, and wearable data, providing both theoretical foundations and practical insights. This book is essential for healthcare professionals, data scientists, and engineers, offering clear frameworks for integrating diverse data types. It addresses crucial issues like data interoperability, privacy, and technical constraints, providing practical solutions. It serves as an invaluable reference for understanding and applying AI advancements in diagnostic precision and personalized medicine.

  • Kinase Targets and Drug Discovery

    • 1 Edición
    • Xiaoyun Lu
    • Inglés
    Kinase Targets and Drug Discovery covers the critical role of kinases as regulators of cellular functions and their implications in a range of diseases, from cancers to cardiovascular disorders and inflammatory conditions. Readers will explore foundational concepts on the functions of kinases, the role of kinase inhibitors in disease therapy, and challenges faced. The second section focuses on innovative strategies in kinase drug discovery, covering screening and computational approaches, along with the development of covalent, macrocyclic, allosteric inhibitors, and kinase degraders. Final sections examine clinical applications, detailing how kinase inhibition can be harnessed for cancer therapies, non-oncologic diseases, and even non-catalytic functions.This book will serve as an indispensable resource for pharmacologists, medicinal chemists, and researchers in both academia and industry. By bridging the gap between foundational research and clinical application, it equips professionals with the latest insights and practical approaches to advance their understanding to contribute meaningfully to the evolving landscape of drug discovery.

  • Reverse Aging

    Current Research and Future Directions
    • 1 Edición
    • Sandeep Kumar Singh + 1 más
    • Inglés
    Reverse Aging: Current Research and Future Directions explores the integrated approach of aging and reverse aging to present a comprehensive understanding of the biological, genetic, and molecular mechanisms associated with aging. By targeting fundamental aging mechanisms, strategies are being developed to reverse and repair damage and potentially lead to greater healthspan benefits and optimal longevity. The book opens with the fundamentals of aging and how genetic, environmental, and lifestyle variables affect the biological, psychological, and social processes that lead to aging before delving into a comprehensive review of the hallmarks of aging. Next, an overview of the concept of reverse aging is presented, and subsequent chapters examine specific reverse aging models and approaches. The book explores use of cellular reprogramming techniques, provides an overview of the molecular processes that underlie NANOG-mediated reversal aging, and discusses the possible contribution of IGF-1/PKA signaling reduction to reverse aging via HSC-based therapies. The developing science of rejuvenating stems cells, histone modification, and stimulation of autophagic activity to facilitate the removal of cellular debris and reduce the impact of aging on various organ systems as well as novel concepts of mRNA enhanced cell therapy, immunological-driven signaling, mitochondrial modulations, cell-cycle regulation, and metabolic reprogramming for reserve aging are all examined. The wide range of nutritional therapies, phytochemical, prescription medications, and nutraceuticals impacting the aging process is reviewed, and the book closes with discussion of the revolutionary role AI has on anti-aging research and where the field is headed. In conclusion, the book emphasizes the importance of targeting fundamental aging mechanisms to extend health and achieve optimal longevity and provides insights into the potential implications for healthcare and aging research, highlighting the need for collaborative efforts and interdisciplinary perspectives to address the challenges of population aging and develop effective strategies for healthy aging practices.

  • Telehealth in Movement Disorders

    Principles, Strategies, Applications, and New Directions
    • 1 Edición
    • Wael Mohamed + 2 más
    • Inglés
    The COVID-19 pandemic forced the world to pause and reevaluate how we operate specifically in medicine, shifting to telemedicine and telehealth. Integrating telemedicine and telehealth into the healthcare system enables patient safety and has been proven beneficial to medical and surgical practices including patient primary care. Telehealth in Movement Disorder: Principles, Strategies, Applications, and New Directions provides guidance on how to deliver clinical assessment and treatment to movements disorders patients through telemedicine. This book is divided into three distinct sections. The first section reviews general principles including strategies, standards, policies, and ethical aspects. The second section explores how telemedicine can be integrated into diagnosis, treatment, and care of patients with movement disorders including the use of new AI technologies. The final section discusses the integration and application of telemedicine in developing countries, including challenges and future opportunities.

  • Inflammatory Arthritis Beyond the Joints

    Comorbidities and other Manifestations
    • 1 Edición
    • Volumen 18
    • Fabiola Atzeni + 1 más
    • Inglés
    Inflammatory Arthritis Beyond the Joints, Volume 18 in Elsevier’s Handbook for Systemic Autoimmune Diseases series, provides an extensive review of the most recent research on various comorbidities and EAMs associated with inflammatory arthritis. The book emphasizes early detection, which is crucial for improving patient quality of life and survivability outcomes, as many adults with inflammatory arthritis also suffer from other chronic conditions. The book's chapters cover comorbidities and EAMs in both early and late disease stages.They delve into the mechanisms behind the development of these conditions and examine the impact of new treatment strategies specific to inflammatory arthritis and related diseases, including cardiovascular disease, metabolic syndrome, metabolic bone disease, infection, neoplasia, respiratory disease, gastrointestinal disorders, kidney issues, mental health conditions, and neurological diseases. This book serves as a valuable reference for researchers and clinicians focused on inflammatory arthritis and its associated conditions.

  • Artificial Intelligence for Multi-omics Analysis Part A

    • 1 Edición
    • Volumen 221
    • Inglés
    Artificial Intelligence for Multi-omics Analysis, Part A, Volume 221 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as an Introduction to Artificial Intelligence in Multi-omics Analysis, Multi‐omics application in health and diseases, Artificial Intelligence in Genomics Analysis, Artificial Intelligence in Single-cell and Spatial Transcriptomics Data, Artificial Intelligence in the prediction of 3D chromatin structure and gene regulation, Artificial intelligence in Mass Spectrometry-based Proteomics, Integrating Artificial Intelligence into Metabolomics for Predicting Diseases, and more.Additional chapters cover Artificial Intelligence in Microbial Metagenomics, Artificial Intelligence in Interactomics, Artificial Intelligence Integration in Medical Imaging Data, AI in biomolecular structural data analysis, Artificial intelligence in Cryo-Electron Microscope data, Explainable artificial intelligence for multi-omics data, and Multi-Omics Cancer Stratification: from Statistical to Deep Learning Perspective.

  • From Conventional to Artificial Intelligence-Based Agriculture

    • 1 Edición
    • Vivek Sharma + 2 más
    • Inglés
    From Conventional to Artificial Intelligence-Based Agriculture explores the evolving landscape of agriculture as it transitions from traditional practices to advanced, AI-driven solutions. With AI and machine learning revolutionizing industries worldwide, their impact on agriculture is becoming increasingly significant. These technologies are not only aiding in climate modeling but also opening new possibilities for precision farming, enabling more accurate crop health diagnostics, efficient resource management, and timely intervention strategies.By integrating conventional agricultural knowledge with cutting-edge AI tools, farmers and researchers can better assess soil conditions, predict optimal planting windows, monitor nutrient dynamics, and understand market trends with greater precision. This convergence of tradition and technology supports more resilient, productive, and sustainable agricultural systems, paving the way for a smarter and more food-secure future.

  • Cell Death Part A

    • 1 Edición
    • Volumen 205
    • Inglés
    Cell Death, Part A, Volume 205 explores the diverse mechanisms and methodologies underlying cell death, providing an up-to-date resource for researchers and clinicians in the biomedical sciences. Chapters in this new release include Methodologies for Monitoring Alkaliptosis in Cancer Cells, Protein-complementat... assay and DISC analysis, Detecting phosphorylated MLKL in murine tissues, Establishment of different cell death models (Apoptosis, Necroptosis, Pyroptosis), Implementation of the FENIX assay to determine anti-ferroptotic properties of test compounds, CRISPR-Cas9 knockout screens to identify drug resistance genes in Acute Myeloid Leukemia, and much more.Additional chapters cover Cell death assays for the detection of acute kidney tubular necrosis, Methods of cell death imaging by Incucyte and similar platforms, Super-resolution microscopy-based assessment of organellar redox-active iron distribution and its relevance for ferroptosis, Monitoring inflammasome activation by analyzing ASC specks and oligomerization, LPS-induced sepsis/ and TNF-induced SIRS (In vivo cell death models), Evaluating protease activation and inactivation of gasdermin cell death effectors, and Measurement of plasma membrane rupture via confocal microscopy.

  • Nanotechnology in the Treatment of Infertility

    Practical Applications and Future Insights
    • 1 Edición
    • Pankaj Sharma
    • Inglés
    Nanotechnology in the Treatment of Infertility: Practical Applications and Future Insights delves into the area where nanotechnology meets reproductive health care and reveals how the latest nanoscale developments are changing how infertility is treated. It examines current developments, principles, and possibilities of nanotechnology, with an emphasis on nanoparticle delivery systems, bioengineering, and their relevance in Assisted Reproductive Technologies (ART). This edited volume, written by leading scholars, provides a comprehensive overview of nanotechnology in relation to fertility. It will be of great interest to researchers, healthcare professionals, and anyone who wants to know more about this exciting area of potential solutions for infertility.

  • Minimally Invasive Spine Techniques

    Modern Approaches
    • 1 Edición
    • Timothy R. Deer + 1 más
    • Inglés
    An essential guide for mastering modern implantable devices in spine, brain, and nerve surgeries, offering comprehensive insights and cutting-edge techniques for optimal clinical outcomesMinimally Invasive Spine Techniques: Modern Approaches is an indispensable resource tailored for practitioners facing the daily challenges demanding precision, innovation, and comprehensive knowledge. This edited reference not only provides a detailed exploration of anatomy critical to procedural success but also equips practitioners with the latest techniques and tools in minimally invasive surgery. From patient selection criteria to surgical techniques and device applications, this atlas ensures that every facet of device implantation is approached with the highest standards of care and innovation. Richly illustrated with a pictorial atlas of best practices, it serves as an essential guide for training, ensuring optimal outcomes in clinical practice.

  • Developing Solid Oral Dosage Forms

    Pharmaceutical Theory and Practice
    • 3 Edición
    • Yihong Qiu + 4 más
    • Inglés
    Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Third Edition is a comprehensive and up-to-date guide for professionals and academics engaged in all aspects of oral dosage form development, from discovery support through commercial manufacturing. This new edition features 13 new or rewritten chapters, along with significant updates to existing content, reflecting the latest advancements in the field, including new theories, scientific findings, approaches, techniques, modeling, and the emerging opportunities offered by AI.This book consists of 44 chapters covering in-depth principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their applications throughout the R&D process and commercial production of oral dosage forms. New chapters address topics such as absorption evaluation of oral dosage forms, formulation principles, and applications based on supersaturation, patient-centric product design, product design through the 505(b)(2) NDA pathway, design of experiments (DoE), process modeling, 3D printing, and machine learning applications in commercial manufacturing. Existing chapters have been updated or completely rewritten to provide advanced information and include practical case studies. Important topics such as amorphous solid dispersions, modified-release delivery, manufacturing technologies, modeling and simulation, fundamentals of dissolution and bioequivalence, IVIVC, biowaivers, regulatory frameworks, and many others are covered.The new edition of this book is an indispensable resource for industry professionals, academic institutions, and regulatory bodies seeking to stay current with advances in solid dosage form development and manufacturing. It offers a thorough understanding of fundamental principles and techniques, along with practical guidance on applying these concepts to real-world challenges.

  • Advances in Sheep Welfare

    • 2 Edición
    • Drewe Ferguson + 3 más
    • Inglés
    Advances in Sheep Welfare, Second Edition provides a detailed reference on advancements in sheep welfare. The book contains the most current knowledge on breeding practices, animal affective states, management strategies, farming and production practices, and the role of society and consumers in shaping the welfare debate. In addition to updating all chapters from the previous edition, completely new chapters are included on behavioral assessments of sheep welfare, the impact of climate change, and drivers of change for sheep producers. Stakeholders across the wool, dairy, and sheep meat supply chains will also benefit from this resource.The book brings together a team of international experts to create the definitive resource on sheep welfare. It will serve as a key reference for researchers, instructors, and students at the post-graduate level who are interested in animal agriculture, especially those who study sheep and issues of animal welfare.

  • Direct-Acting Antivirals against Hepatitis C

    Current Issues and Future Perspectives
    • 1 Edición
    • Mohamed Mahmoud Zakaria El-Kassas
    • Inglés
    Direct-Acting Antivirals against Hepatitis C: Current Issues and Future Perspectives is a comprehensive reference that explores Chronic Hepatitis C management. This authoritative reference covers the mechanisms, efficacy, and future potential of Direct-Acting Antivirals (DAAs), offering valuable insights for clinicians, researchers, and students in hepatology and infectious diseases. Structured into three sections, this reference covers a wide range of topics related to DAAs in the management of Hepatitis C. In Section 1, readers will gain a thorough understanding of HCV infection, its clinical significance, and the immune response involved. They will also explore the molecular mechanisms of DAAs and the different classes available. Section 2 focuses on the practical aspects of using DAAs in the treatment of HCV. Readers will discover the clinical efficacy of different DAA regimens, the safety and tolerability considerations, and the additional benefits of DAA treatment beyond virological response. The section also covers current treatment guidelines and individualized approaches for specific patient populations. In Section 3, readers will learn the challenges and future directions in DAA therapy including antiviral resistance in HCV and strategies for managing and overcoming resistance. The book also explores the relationship between DAA therapy and hepatocellular carcinoma, as well as the current limitations and unmet needs in DAA therapy.Direct-Actin... Antivirals against Hepatitis C: Current Issues and Future Perspectives is a comprehensive and indispensable resource for anyone involved in the management of Chronic Hepatitis C. With its in-depth exploration of DAAs, from their molecular mechanisms to their clinical applications and future directions, this book equips clinicians, researchers, and students with the knowledge and insights needed to enhance their practices and contribute to the global fight against HCV infection.

  • Fundamentals of Molecular Structural Biology

    • 2 Edición
    • Subrata Pal
    • Inglés
    Fundamentals of Molecular Structural Biology, Second Edition reviews the mathematical and physical foundations of molecular structural biology, covering the latest advancements. The book begins with historical perspectives before exploring mathematical concepts, physical aspects of chemistry, the chemical basis of biology, structural analysis, visualization, protein folding, transcription, RNA processing, cell signaling, and computational molecular biology. Additionally, this new edition delves into AI fundamentals and applications, including AlphaFold and RoseTTAFold. This fully updated edition provides a detailed overview of the fundamental concepts across molecular structural biology and acts as an ideal guide for researchers and advanced students.Given the increasingly interdisciplinary nature of this subject, this book provides early career researchers and those shifting into an adjacent field a "fundamentals" resource to get them up-to-speed on the foundations of a particular field.

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