Saltar al contenido principal
Elsevier

Libros en Ciencias de la Vida

  • Adverse Effects of Engineered Nanomaterials

    Exposure, Toxicology, and Impact on Human Health
    • 2 Edición
    • Bengt Fadeel + 2 más
    • Inglés
    Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population.

  • Multi-Scale Approaches in Drug Discovery

    From Empirical Knowledge to In silico Experiments and Back
    • 1 Edición
    • Alejandro Speck-Planche
    • Inglés
    Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computat... methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents. After an introduction to multi-scale approaches outlining the need for and benefits of their use, the book goes on to explore a range of useful techniques and research areas, and their potential applications to this process. Profiling drug binding by thermodynamics, machine learning for predicting enzyme sub-classes, and multitasking models for computer-aided design and virtual compound screening are discussed, before the book goes on to review Alkaloid Menispermaceae leads, natural chemotherapeutic agents and methods for speeding up the design and virtual screening of therapeutic peptides. Flavonoids as multi-target compounds are then explored, before the book concludes with a review of Quasi-SMILES as a novel tool. Collecting together reviews and original research contributions written by leading experts in the field, Multi-Scale Approaches to Drug Discovery highlights cutting-edge approaches and practical examples of their implementation for those involved in the drug discovery process at many different levels. Using the combined knowledge of medicinal, computational, pharmaceutical and bio- chemists, it aims to support growth in the multi-scale approach to promote greater success in the development of new drugs.

  • Stress and Epigenetics in Suicide

    • 1 Edición
    • Vsevolod Rozanov
    • Inglés
    Stress and Epigenetics in Suicidediscusses the central role of epigenetic modifications in suicidal behavior. As early-life stress and an individual's ability to cope with such stressors, combined with psychological factors, social factors, and existential and cognitive factors can predispose young people to suicidal behavior and put them at added risk of suicidal behavior later in life, this book provides readers with an overview of the neurobiology of stress, an introduction to the epigenetic changes induced by stress, and an understanding of how vulnerability and resilience to stress are built. It integrates these mechanisms into a biobehavioral model of suicide based on epigenetic marks, gene-environment interactions, and other stressors. More importantly, it provides future direction for research and discusses potential interventions. This book is an ideal and trusted resource for researchers and clinicians who are interested in learning how the environment can affect behavior through genetics, and for those seeking the development of new methods for suicide prevention.

  • Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices

    • 1 Edición
    • Ashim K Mitra + 2 más
    • Inglés
    Emerging Nanotechnologies for Diagnostics, Drug Delivery and Medical Devices covers the modern micro and nanotechnologies used for diagnosis, drug delivery, and theranostics using micro, nano, and implantable systems. In-depth coverage of all aspects of disease treatment is included. In addition, the book covers cutting-edge research and technology that will help readers gain knowledge of novel approaches and their applications to improve drug/agent specificity for diagnosis and efficient disease treatment. It is a comprehensive guide for medical specialists, the pharmaceutical-indus... and academic researchers discussing the impact of nanotechnology on diagnosis, drug delivery, and theranostics.

  • Vascular Pharmacology

    Smooth Muscle
    • 1 Edición
    • Volumen 78
    • Inglés
    Vascular Pharmacology: Smooth Muscle provides up-to-date information on the structure, function, signaling, and development of vascular smooth muscle. Contributors include prominent scientists and highly-recognized experts with major accomplishments in the field of vascular smooth muscle research.

  • Fish Diseases

    Prevention and Control Strategies
    • 1 Edición
    • Galina Jeney
    • Inglés
    Fish Diseases: Prevention and Control Strategies provides essential information on disease prevention and treatment by the most experienced fish culturists in the industry. The book presents both traditional and novel methodologies of identifying and addressing fish disease risk, along with preventative and responsive insights to the challenges impacting fish production today. Both specific (vaccination) and non-specific (immunostimulation) approaches are explored, from maintaining optimal environmental conditions, to understanding how stressors in fish affect their immune system.

  • The Heart in Systemic Autoimmune Diseases

    • 2 Edición
    • Volumen 14
    • Fabiola Atzeni + 3 más
    • Inglés
    The Heart in Systemic Autoimmune Diseases, Second Edition, provides an overview on our current understanding of major complications relating to the heart and autoimmune diseases. It includes the latest information on the new pathogenetic mechanisms involved, along with clinical manifestations of these important comortbidities. Mortality in autoimmune diseases, in particular, rheumatoid arthritis and SLE, has increased when compared with the general population. This excess mortality is largely due to cardiovascular diseases (CVDs)-particularly those of atherosclerotic origin, such as ischemic heart disease-and is gaining recognition in all branches of medicine, from cardiology, to internal medicine, and from rheumatologists to orthopedics.

  • Primer on Cerebrovascular Diseases

    • 2 Edición
    • Louis R. Caplan + 6 más
    • Inglés
    Primer on Cerebrovascular Diseases, Second Edition, is a handy reference source for scientists, students, and physicians needing reliable, up-to-date information on basic mechanisms, physiology, pathophysiology, and medical issues related to brain vasculature. The book consists of short, specific chapters written by international experts on cerebral vasculature, presenting the information in a comprehensive and easily accessible manner. Numerous changes have occurred in the field since the publication of the first edition in 1997, particularly our understanding of the genetic aspects of cerebrovascular disease. This updated edition reflects the advances made over the last two decades, not only demonstrating the promise for therapy, but also for a molecular understanding of cerebrovascular diseases. The new edition includes new and expanded topics, including carotid stenting, Iatrogenic causes of stroke, axonal transport and injury, RNAIs, proteomics, and more. 2018 BMA Medical Book Awards Highly Commended in Neurology.

  • New Pesticides and Soil Sensors

    • 1 Edición
    • Alexandru Mihai Grumezescu
    • Inglés
    New Pesticides and Soil Sensors, a volume in the Nanotechnology in the Agri-Food Industry series, is a practical resource that demonstrates how nanotechnology is a highly attractive tool that offers new options for the formulation of ‘nanopesticides’. Recent advances in nanopesticide research is reviewed and divided into several themes, including improvement of the water solubility of poorly soluble pesticide active ingredients to improve bioavailability and the encapsulation of pesticide active ingredients within permeable nanoparticles with the aim of releasing pesticide active ingredients in a controlled or targeted manner, while also protecting active ingredients from premature photo-degradation.

  • The Heart in Rheumatic, Autoimmune and Inflammatory Diseases

    Pathophysiology, Clinical Aspects and Therapeutic Approaches
    • 1 Edición
    • Udi Nussinovitch
    • Inglés
    The prevalence of autoimmune diseases and rheumatic conditions is constantly increasing. Autoimmune diseases affect approximately 7-10% of the population of the United States, while more than 50,000,000 American adults suffer from some type of arthritis. The Heart in Rheumatic, Autoimmune and Inflammatory Diseases examines the complex mechanisms relating to cardiac diseases from a pathophysiological and clinical point of view. Autoimmune rheumatic diseases can affect the coronary vessels, myocardium, pericardium, heart valves and the conduction system. The diagnosis of these unique cardiac complications necessitates medical awareness and a high index of suspicion. Increased risk of advanced atherosclerosis plays a pivotal role in the development of cardiac diseases in systemic, rheumatic and autoimmune illnesses. Yet, other complex immune medicated mechanisms may contribute to the pathogenesis. Patients' optimal care requires coordination between the primary caregiver, the rheumatologist, immunologist and cardiologist. Screening for cardiovascular risk factors, recognition of high-risk patients and identification of subclinical cardiac conditions are of great importance. Moreover, regulation of inflammation, as well as abnormal immune responses and the initiation of early treatments should be the focus of patient management. A continuous attempt to identify novel therapeutic targets and change the natural history of the underlying disease and its cardiac manifestations is in progress. The book aims at providing the readers with a state of the art collection of up to date information regarding clinically important topics based on experts' perspectives. This book was a result of an extended coordinated collaboration of one-hundred and fifty-four distinguished scientists from thirty-one countries around the globe.

  • The Human Sciences after the Decade of the Brain

    • 1 Edición
    • Jon Leefmann + 1 más
    • Inglés
    The Human Sciences after the Decade of the Brain brings together exciting new works that address today’s key challenges for a mutual interaction between cognitive neuroscience and the social sciences and humanities. Taking up the methodological and conceptual problems of choosing a neuroscience approach to disciplines such as philosophy, history, ethics and education, the book deepens discussions on a range of epistemological, historical, and sociological questions about the "neuro-turn" in the new millennium. The book’s three sections focus on (i) epistemological questions posed by neurobiologically informed approaches to philosophy and history, (ii) neuroscience’s influence on explanations for social and moral behavior, and (iii) the consequences of the neuro-turn in diverse sectors of social life such as science, education, film, and human self-understanding. This book is an important resource both for students and scholars of cognitive neuroscience and biological psychology interested in the philosophical, ethical, and societal influences of—and on—their work as well as for students and scholars from the social sciences and humanities interested in neuroscience.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 98
    • Inglés
    Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology, containing comprehensive reviews of the most current research in applied microbiology. Users will find invaluable references and information on a variety of areas, including protozoan grazing of freshwater biofilms, metals in yeast fermentation processes, the interpretation of host-pathogen dialogue through microarrays, and the role of polyamines in bacterial growth and biofilm formation. Eclectic volumes are supplemented by thematic volumes on various topics, including Archaea and sick building syndrome.

  • Ecology and Evolution of Cancer

    • 1 Edición
    • Beata Ujvari + 2 más
    • Inglés
    Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field. The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures.

  • Translational Immunotherapy of Brain Tumors

    • 1 Edición
    • John H. Sampson
    • Inglés
    Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. 2018 BMA Medical Book Awards Highly Commended in Oncology

  • Foodborne Diseases

    • 3 Edición
    • Christine ER Dodd + 2 más
    • Inglés
    Foodborne Diseases, Third Edition, covers the ever-changing complex issues that have emerged in the food industry over the past decade. This exceptional volume continues to offer broad coverage that provides a foundation for a practical understanding of diseases and to help researchers and scientists manage foodborne illnesses and prevent and control outbreaks. It explains recent scientific and industry developments to improve awareness, education, and communication surrounding foodborne disease and food safety. Foodborne Diseases, Third Edition, is a comprehensive update with strong new topics of concern from the past decade. Topics include bacterial, fungal, parasitic, and viral foodborne diseases (including disease mechanism and genetics where appropriate), chemical toxicants (including natural intoxicants and bio-toxins), risk-based control measures, and virulence factors of microbial pathogens that cause disease, as well as epigenetics and foodborne pathogens. Other new topics include nanotechnology, bioterrorism and the use of foodborne pathogens, antimicrobial resistance, antibiotic resistance, and more.

  • Ticks of the Southern Cone of America

    Diagnosis, Distribution, and Hosts with Taxonomy, Ecology and Sanitary Importance
    • 1 Edición
    • Santiago Nava + 4 más
    • Inglés
    Ticks of the Southern Cone of America: Diagnosis, Distribution and Hosts with Taxonomy, Ecology and Sanitary Importance focuses on the tick species prevalent in The Southern Cone of America, including their distribution, biology, associated pathogens, their effects on the host, and control methods. Based on review of the literature from more than five decades, 62 species of both hard and soft tick have been discovered on the Southern Cone of America. Tick genera observed and recorded include Amblyomma, Dermacentor, Haemaphysalis, Ixodes, and Rhipicephalus.

  • Mathematics for Neuroscientists

    • 2 Edición
    • Fabrizio Gabbiani + 1 más
    • Inglés
    Mathematics for Neuroscientists, Second Edition, presents a comprehensive introduction to mathematical and computational methods used in neuroscience to describe and model neural components of the brain from ion channels to single neurons, neural networks and their relation to behavior. The book contains more than 200 figures generated using Matlab code available to the student and scholar. Mathematical concepts are introduced hand in hand with neuroscience, emphasizing the connection between experimental results and theory.

  • Nutrition and Functional Foods for Healthy Aging

    • 1 Edición
    • Ronald Ross Watson
    • Inglés
    Nutrition and Functional Foods for Healthy Aging aims to equip anyone studying geriatric nutrition or working with aging adults with the latest scientific reviews of critical topics. The major objective of this book is to review, in detail, the health problems of the aged and how normal food, lifestyle, or nutritional and dietary supplements can help treat them. Nutrient requirements for optimum health and function of aging physiological systems are often quite distinct from those required for young people. The special nutrition problems of the aged are intensively researched and tested, especially as the elderly become a larger percentage of the population. Many chronic diseases and cancers are found with higher frequency in the aged, and it is also widely known that many elderly people use foods and nutrients well above the recommended daily allowance, which can be detrimental to optimal health.

  • Rare and Interesting Cases in Pulmonary Medicine

    • 1 Edición
    • Ali Ataya + 1 más
    • Inglés
    Rare and Interesting Cases in Pulmonary Medicine provides a look into the uncommon diseases encountered in the field of pulmonary medicine. Using a case-based approach, the book provides clinical scenarios that include relevant accompanying radiology and pathology. Also included are frequently asked questions for each area, as well as a diagnosis and summary, presenting the reader with the most high yield information on each topic. Appropriate for medical students, residents, fellows, and physicians interested in pulmonary medicine, the case-based approach to each topic allows accessibility to the uncommon diseases of the field while also highlighting high yield and important points.

  • Light and Life in the Universe

    Selected Lectures in Physics, Biology and the Origin of Life
    • 1 Edición
    • S. T. Butler + 1 más
    • Inglés
    Light and Life in the Universe: Selected Lectures in Physics, Biology and the Origin of Life is a collection of lectures given at the 1964 Nuclear Research Foundation Summer Science School for High School Students, held at the University of Sydney, Australia, on January 6-17, 1964. The papers explore various aspects of life, both on earth and in the universe generally. Emphasis is placed on the ""units"" of living matter, how life may have started on earth, and the possibility of life on other planets. This book is comprised of 15 chapters and begins with a brief description of some of the properties of atoms and how they join up to form molecules, as well as some of the properties of the central core of each atom. The discussion then turns to electromagnetic radiation, highlighting the difficulties originally encountered by Ernest Rutherford's picture of the atom. Subsequent chapters focus on the influence of gravitational fields; the origin of the solar system; the evolution of life on earth; and link between the primordial atmosphere and the origin of life. The functions of proteins, the practical effects of biology on humans, and the replication of living molecules are also considered. This monograph is written specifically for fourth-year high school students interested in astronomy, physics, chemistry, and biology.

  • Pharmacology of Cholinergic and Adrenergic Transmission

    Proceedings of the Second International Pharmacological Meeting, August 20—23, 1963
    • 1 Edición
    • G. B. Koelle + 2 más
    • Inglés
    Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 3: Pharmacology of Cholinergic and Adrenergic Transmission focuses on the effects of drugs on muscles, nerve fibers, and the central nervous system. The selection first offers information on the role of sodium ions in the release of acetylcholine and the distribution and release of acetylcholine in muscles. Discussions focus on the effects of sodium deficiency on ACh release in perfused ganglia; effects of sodium pump inhibitors on ganglionic and myoneural transmission; distribution of ACh and choline acetylase in muscle; and ACh release after denervation. The text then ponders on the roles of acetylcholine and acetylcholinesterase in junctional transmission and correlated studies of monoamines and acetylcholinesterase in sympathetic ganglia, manifesting the distribution of adrenergic and cholinergic neurons. The publication examines the action of acetylcholine and related drugs on mammalian nonmyelinated nerve fibers; possible mechanisms of acetylcholine action in muscles; and electrophysiological analysis of cholinergic transmission in sympathetic ganglia. The text then reviews the interactions of cholinomimetic and cholinergic blocking drugs at sympathetic ganglia; evolution of cholinoreceptive sites of locomotor muscle; and pharmacological blocking of central cholinoreactive systems and the possibilities of its therapeutic application. The selection is a dependable source of data for readers interested in the pharmacology of cholinergic and adrenergic transmission.

  • Morphology and Evolution of the Insect Abdomen

    With Special Reference to Developmental Patterns and Their Bearings upon Systematics
    • 1 Edición
    • Ryuichi Matsuda
    • G. A. Kerkut
    • Inglés
    Morphology and Evolution of the Insect Abdomen: With Special Reference to Developmental Patterns and Their Bearings Upon Systematics focuses on the morphology and evolution of the skeletal structures of the insect abdomen and the internal reproductive system. Emphasis is placed on patterns of development and their implications for systematics. Comprised of 44 chapters, this book begins with an introduction to the principles of structural evolution, paying particular attention to morphogenetical regularities and anagenesis, heterochrony, substitution and homology, and analogy. The next section is devoted to various aspects of the insect abdomen including abdominal segmentation, appendages, and ovipositor as well as the male external genitalia, the male and female efferent duct, and the abdominal ganglia. The final section deals with the abdomen of a wide range of insect classes such as Protura, Collembola, Orthoptera, Coleoptera, Homoptera, Mantodea, and Diptera. This monograph will be of interest to entomologists, physiologists, and evolutionary biologists.

  • An Outline of Developmental Physiology

    International Series of Monographs in Pure and Applied Biology: Zoology
    • 1 Edición
    • Chr. P. Raven
    • G. Kerkut
    • Inglés
    An Outline of Developmental Physiology was first published in the Dutch language in 1948, while the first English edition appeared in 1954. It was meant in the first place for readers who, though interested in its subject and having some general knowledge of science, were not acquainted with more than the first elements of biology. This new edition has been brought up to date by taking into account the literature up to about the middle of 1963. The book opens with a discussion of the fusion of sperm and egg. This is followed by separate chapters that explain the series of processes that transform the initially fairly homogeneous structure of the egg into a system with a considerable degree of spatial multiplicity. This book may be used as a preliminary introduction into the field in undergraduate classes. A list of references has been added in the interest of those who might want to refer to the original publications on some special problem. Moreover, a glossary of scientific terms has been included for the benefit of those readers who are not professional biologists.

  • Drugs, Alcohol and Tobacco in Britain

    • 1 Edición
    • Jim Zacune + 1 más
    • Inglés
    Drugs, Alcohol, and Tobacco in Britain focuses on the use and misuse of drugs, alcohol, and tobacco and the British response to these substances. The manuscript first tackles alcohol production, sale, and control and production of drugs. Discussions focus on licensing laws in England and Wales, taxation, home brewing and distilling, detailed incidence of liquor duties, illicit production of alcoholic beverages, overseas trade, and tied-house system. The book then elaborates on the control of drugs, including international control, Dangerous Drugs Act, 1965, United Kingdom laws, and control of specific psycho-active drugs. The publication examines the "normal" use of alcohol in Great Britain, medical use of drugs, and a historical perspective of alcohol abuse in Great Britain. Topics include medical use of cannabis, amphetamines, and opiates, student drinking, medical use of alcohol, expenditure on alcohol, and alcohol consumption. The text then takes a look at the misuse of alcohol in Great Britain, non-medical use of cannabis, non-medical use of Lysergic Acid Diethylamide and hallucinogenic drugs, and non-medical use of hypnotics and tranquillizers. The book is a valuable source of information for readers wanting to study the use and abuse of drugs, alcohol, and tobacco in Great Britain.

  • Recent Advances in Animal Nutrition 1991

    • 1 Edición
    • W. Haresign + 1 más
    • Inglés
    Recent Advances in Animal Nutrition: 1991 is an annual review of the changes and updates in the field of animal nutrition, especially progresses in the study of feeds. The book is divided into five parts. Part I discusses topics related to pig nutrition and feeds such as energy-protein interactions and improved utilization of amino acids. Part II covers the nutrition and growth of poultry. Part III talks about the legislations concerned with feed manufacture, and Part IV deals with nutrition of different animals such as chicks and ruminants. The text is recommended for agriculturists, zoologists, and those involved in the development and manufacture of feeds who would like to know more about the nutrition of agriculturally important animals.

  • Genetics of Scots Pine

    • 1 Edición
    • Volumen 3
    • M. Giertych + 1 más
    • Inglés
    Since the Scots pine species is most important in Eurasia, it was considered necessary to involve authors from as many countries as was possible including Eastern Europe and U.S.S.R. During the 18th IUFRO World Congress in Ljubljana, Yugoslavia, in September 1986, details were worked out for the contents of this book.This book is a truly international effort, prepared in the traditional IUFRO spirit of selfless co-operation. In all, 24 authors from 9 countries are involved. Each chapter was reviewed by two editors from two different countries.

  • Short Guide to Geo-Botanical Surveying

    International Series of Monographs on Pure and Applied Biology, Division: Botany
    • 1 Edición
    • S. V. Viktorov + 2 más
    • R. C. Rollins + 1 más
    • Inglés
    International Series of Monographs on Pure and Applied Biology, Volume 8: Short Guide to Geo-Botanical Surveying focuses on the guide used in the geo-botanical surveying of pastures, bogs, and forests. The book first offers information on geo-botanical maps and plans and geo-botanical surveys. Discussions focus on the general features of geo-botanical maps and plans, classification of geo-botanical maps, transect surveys, auxiliary methods of investigation in geo-botanical surveys, and aero geo- botanical surveys. The text then examines geo-botanical surveys for forestry needs, including survey work in forest valuation, forest-typology surveys, and notes on interpretation of aerial photographs of forest vegetation. The publication ponders on geo-botanical surveys for the needs of the peat industry and agricultural reclamation of bogs and geo-botanical surveys for study of pastures. Topics include geo-botanical survey of bogs in connection with their agricultural reclamation; general information on geo-botanical surveys in bogs; features of surveys in semi-deserts and deserts; and features of surveys on the tundra. The text is a valuable source of data for readers interested in geo-botanical surveying.

  • Clinical and Experimental Toxicology of Organophosphates and Carbamates

    • 1 Edición
    • Bryan Ballantyne + 1 más
    • Inglés
    Clinical & Experimental Toxicology of Organophosphates and Carbamates considers the histochemical localization of cholinesterase in anticholinesterase poisoning. This book is organized into eight parts encompassing 59 chapters that discuss the pharmacology and toxicology of carbamates, as well as the neurobehavioral toxicology of anticholinesterases. Some of the topics covered in the book are the overview of biological and clinical aspects of organophosphates and carbamates; biochemical determination of cholinesterase activity in fluids and tissues; intermediate syndrome in anticholinesterase neurotoxicity; structure-activity relationships and anticholinesterase activity; and the molecular events in delayed neuropathy. Other parts deal with the cardiac effects of anticholinesterase agents and the ecotoxicological consequences of interactions between avian esterases and organophosphorus compounds. These topics are followed by discussions on the analysis of the cutaneous and respiratory tract absorption of anticholinesterases and the use of organophosphorus compounds as chemical warfare agents. The final parts are devoted to the toxicity of anticholinesterases to aquatic organisms. The book can provide useful information to toxicologists, doctors, students, and researchers.

  • Recent Advances in Animal Nutrition – 1980

    Studies in the Agricultural and Food Sciences
    • 1 Edición
    • William Haresign
    • Inglés
    Recent Advances in Animal Nutrition – 1980 is a collection of papers that deals with the nutritional concerns of both ruminants and non-ruminants livestock. The book presents a total of 13 papers that cover various issues in animal husbandry. The first half of the text deals with ruminant nutrition. The coverage of this part includes feed input-milk output relationships in the autumn-calving dairy cow; microbial protein synthesis and digestion in the high-yielding dairy cow; and the contribution of undegraded protein to the protein requirements of dairy cows. Next, the book covers studies related to non-ruminant nutrition, such as energy and protein nutrition of the sow; a bioeconomic model of turkey production; and feeding the replacement pullet. The text will be most useful to both researchers and practitioners of animal related disciplines, such agriculture and veterinary medicine.

  • Immunopharmacology

    Proceedings of the Third International Pharmacological Meeting July 24–30, 1966
    • 1 Edición
    • H. O. Schild + 1 más
    • Inglés
    Immunopharmacology is the 11th volume of the proceedings of the Third International Pharmacological Meeting held at Sao Paulo, Brazil on July 26, 1966. The volume covers papers that deal with immunoglobulins responsible for hypersensitivity reactions and with the mechanisms of these reactions; pharmacological mediators of immediate and delayed hypersensitivity; Arthus reactions; and soluble factors released by the action of antigen on sensitized lymphocytes. The book concludes with a single paper on the subject of penicillin allergy. Immunologists and pharmacologists will find the volume invaluable.

  • An Introduction to Public Health

    • 1 Edición
    • E. W. Caryl Thomas
    • Inglés
    An Introduction to Public Health deals with the administration of public health services in the United Kingdom. This book discusses the local government as partners to national health services. After giving a background of the English local government, the growth of local health services, and the functions of local health services, the author discusses the changing inter-related operations of many agencies such as the medical profession, the hospitals, auxiliaries, and administrative arrangements. Environmental hygiene encompasses the following: potable and sufficient supply of water, efficient drainage, sewerage, and disposal system, as well as appropriate housing and an uncontaminated atmosphere. The author also addresses the school health service system, the prevention or management of communicable diseases including disinfection, quarantine, and isolation. The author addresses public food safety in terms of food handling, bacterial contamination of food, and transferrable animal diseases. Legislation plays an important role in work conditions, factory hygiene, control of environment, and the effects of certain occupations on health. The author also cites improvements made in the Poor Law Act and in the National Health Insurance scheme. This book can be of interest to English historians, political scientists, officials concerned with public health and safety, as well as policy makers in local government administrations.

  • Proteomics in Biology, Part B

    • 1 Edición
    • Volumen 586
    • Inglés
    Proteomics in Biology, Part B, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in proteomics.

  • Morphological Mouse Phenotyping

    Anatomy, Histology and Imaging
    • 1 Edición
    • Jesus Ruberte + 2 más
    • Inglés
    Morphological Mouse Phenotyping: Anatomy, Histology and Imaging is an atlas of explanatory diagrams and text that guides the reader through normal mouse anatomy, histology, and imaging. The book is targeted for mouse researchers and veterinarian and human pathologists, and presents a complete, integrative description of normal mouse morphology. Disease animal models are fundamental in research to improve human health. The success of using genetically engineered mice to evaluate molecular disease hypotheses has encouraged the development of massive global projects, making the mouse the most used animal disease model. Laboratory mouse populations are straining the housing capacity of pharmaceutical and biotechnology companies, as well as public research institutions. However, the scientific community lacks sufficient expertise in morphological phenotyping to effectively characterize and validate these animal models. The mouse displays fundamental morphological similarities to humans; however, a mouse is not a man.

  • Echinococcus and Echinococcosis, Part A

    • 1 Edición
    • Volumen 95
    • Inglés
    Echinococcus and Echinococcosis Part A and B present a complete synthesis on what is known about the parasitic cestode echinococcus and the disease it causes, echinococcosis (Hydatid Disease), also demonstrating that in addition to its medical, veterinary, and economic significance, it is an intriguing biological phenomenon. Both parts build on the success of a previous volume, Echinococcus and Hydatid Disease, edited by R.C.A. Thompson and A.J. Lymbery, and published by CAB International, that details the major advances that have taken place since its release. As such, it remains the only comprehensive account that embraces virtually all aspects of echinococcus and the disease it causes. The links between laboratory knowledge and field applications are emphasized throughout the volumes. Consequently, research workers, teachers, students of parasitology, clinicians, and field workers will find this work an indispensable source of information.

  • Conceptual Breakthroughs in Ethology and Animal Behavior

    • 1 Edición
    • Michael D. Breed
    • Inglés
    Conceptual Breakthroughs in Ethology and Animal Behavior highlights, through concise summaries, the most important discoveries and scientific revolutions in animal behavior. These are assessed for their relative impact on the field and their significance to the forward motion of the science of animal behavior. Eighty short essays capture the moment when a new concept emerged or a publication signaled a paradigm shift. How the new understanding came about is explained, and any continuing controversy or scientific conversation on the issue is highlighted. Behavior is a rich and varied field, drawing on genetics, evolution, physiology, and ecology to inform its principles, and this book embraces the wealth of knowledge that comes from the unification of these fields around the study of animals in motion. The chronological organization of the essays makes this an excellent overview of the history of animal behavior, ethology, and behavioral ecology. The work includes such topics as Darwin’s role in shaping the study of animal behavior, the logic of animal contests, cognition, empathy in animals, and animal personalities. Succinct accounts of new revelations about behavior through scientific investigation and scrutiny reveal the fascinating story of this field. Similar to Dr. John Avise’s Contemporary Breakthroughs in Evolutionary Genetics, the work is structured into vignettes that describe the conceptual revolution and assess the impact of the conceptual change, with a score, which ranges from 1-10, providing an assessment of the impact of the new findings on contemporary science.

  • Critical Care Neurology Part I

    Neurocritical Care
    • 1 Edición
    • Volumen 140
    • Inglés
    Critical Care Neurology, Part I: Neurocritical Care focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.

  • Translational Advances in Gynecologic Cancers

    • 1 Edición
    • Michael Birrer + 1 más
    • Inglés
    Translational Advances in Gynecologic Cancers straddles the bench and bed divide by highlighting important and interesting research that is translatable to the clinic. The contents of this book cover the entire spectrum, from promising laboratory based research, to clinical trial efforts. Further, new therapeutic indications based upon randomized phase III trials are also included. Clinicians will learn about lab-based science that is about to enter the clinic, along with the rationale behind translational endpoints in trials. Researchers will be able to identify and understand the clinical needs of patients with these types of tumors to improve their research focus.

  • Nutritional Modulators of Pain in the Aging Population

    • 1 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Nutritional Modulators of Pain in the Aging Population provides an overview on the role of foods, dietary supplements, obesity, and nutrients in the prevention and amelioration of pain in various diseases in the aging population. Headaches, fibromyalgia, joint pain, arthritis pain, back pain, and stomach pain are discussed. In addition, the potential health risks of using foods to reduce symptoms is evaluated. Each chapter reviews pain causing conditions before reviewing the role of food or exercise. Both researchers and physicians will learn about dietary approaches that may benefit or harm people with various types of pain. Chapters include current research on the actions of nutrients in pain treatment, the effects of lifestyle and exercise on pain management, and discussions of dietary supplements that provide pain relief from chronic conditions like arthritis.

  • Critical Care Neurology Part II

    Neurology of Critical Illness
    • 1 Edición
    • Volumen 141
    • Inglés
    Critical Care Neurology, Part II: Neurology of Critical Illness focuses on the care specialists and general neurologists that consult in the ICU and their work with patients in acute, life-threatening situations who are dealing with neurologic or neurosurgical crises emanating from either a preexisting neurologic syndrome or from a new neurologic complication appearing as a result of another medical or surgical critical illness. These two separate clinical situations form the pillars of neurocritical care, hence these practices are addressed via two separate, but closely related, HCN volumes. Chapters in both focus on pathophysiology and management, and are tailored for both general neurologists and active neurocritical specialists, with a specific focus on management over diagnostics. Part I addresses the principles of neurocritical care and the management of various neurologic diseases. Part II addresses the interplay between neurologic complications and the surgical, medical, cardiac, and trauma of critical illnesses that most typically present in the ICU.

  • The Zebrafish: Disease Models and Chemical Screens

    • 4 Edición
    • Volumen 138
    • Inglés

  • Insect-Plant Interactions in a Crop Protection Perspective

    • 1 Edición
    • Volumen 81
    • Inglés
    Insect-Plant Interactions, the latest edition in the Advances in Botanical Research series, which publishes in-depth and up-to-date reviews on a wide range of topics in the plant sciences, features several reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology, and ecology.

  • Applications of Mass Spectrometry Imaging to Cancer

    • 1 Edición
    • Volumen 134
    • Inglés
    Applications of Mass Spectrometry Imaging to Cancer, the latest volume in the Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on applications of mass spectrometry imaging to cancer.

  • Proteomics in Biology, Part A

    • 1 Edición
    • Volumen 585
    • Inglés
    Proteomics in Biology Part A, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field, and a focus on proteomics for this updated volume.

  • Early Stage Protein Misfolding and Amyloid Aggregation

    • 1 Edición
    • Volumen 329
    • Inglés
    Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership and maintains a high standard by publishing invited articles on important and timely topics as authored by prominent cell and molecular biologists.

  • The Digestive Involvement in Systemic Autoimmune Diseases

    • 2 Edición
    • Volumen 13
    • Manuel Ramos-Casals + 4 más
    • Inglés
    The Digestive System in Systemic Autoimmune Diseases, Second Edition, represents the state-of-the-art in the field of digestive disorders in the most common systemic autoimmune diseases. This volume consists of an introductory chapter on imaging techniques in digestive diseases, followed by eight chapters on digestive manifestations in specific systemic autoimmune diseases. The final five chapters deal with digestive diseases with an autoimmune pathogenesis and systemic manifestations. International in scope, the table of contents reads like a Who's who in clinical research on systemic autoimmune diseases. More than 20 contributors from the European Union, the United States, Mexico, and South Africa share their knowledge in this detailed volume. The book provides an overview of our current understanding of digestive disorders in the most common systemic autoimmune diseases.

  • American Trypanosomiasis Chagas Disease

    One Hundred Years of Research
    • 2 Edición
    • Jenny Telleria + 1 más
    • Inglés
    American Trypanosomiasis, Chagas Disease: One Hundred Years of Research, Second Edition, provides a comprehensive overview of Chagas disease and discusses the latest discoveries concerning the three elements that compose the transmission chain of the disease, the host, the insect vectors, and the causative parasite. In addition, new insights on the molecular biology and diagnostics of Chagas diseases, the persistence of infections in the host, and the interaction of the parasite and host metabolism are now included in this new and updated edition.

  • Sleep and Neurologic Disease

    • 1 Edición
    • Mitchell G. Miglis
    • Inglés
    Sleep and Neurologic Disease reviews how common neurologic illnesses, such as Parkinson’s Disease and Alzheimer’s dementia impact sleep. In addition, the book discusses how common primary sleep disorders influence neurologic diseases, such as the relationship between obstructive sleep apnea and stroke, as well as their association with various primary headache disorders and epilepsy syndromes. The utilization of sleep technology, such as polysomnography, multiple sleep latency testing, actigraphy, laboratory and CSF testing is also covered. The book is written for the practicing neurologist, sleep physician, neuroscientist, and epidemiologist studying sleep.

  • Innovative Neuromodulation

    • 1 Edición
    • Jeffrey Arle + 1 más
    • Inglés
    Innovative Neuromodulation serves as an extensive reference that includes a basic introduction to the relevant aspects of clinical neuromodulation that is followed by an in-depth discussion of the innovative surgical and therapeutic applications that currently exist or are in development. This information is critical for neurosurgeons, neurophysiologists, bioengineers, and other proceduralists, providing a clear presentation of the frontiers of this exciting and medically important area of physiology. As neuromodulation remains an exciting and rapidly advancing field—appealing to many disciplines—the editors’ initial work (Essential Neuromodulation, 2011) is well complemented by this companion volume.

  • Molecular and Cellular Therapies for Motor Neuron Diseases

    • 1 Edición
    • Nicholas M Boulis + 2 más
    • Inglés
    Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials.

  • Medicinal Spices and Vegetables from Africa

    Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases
    • 1 Edición
    • Victor Kuete
    • Inglés
    Medicinal Spices and Vegetables from Africa: Therapeutic Potential against Metabolic, Inflammatory, Infectious and Systemic Diseases provides a detailed look at medicinal spices and vegetables that have proven safe-and-effective for consumption and the treatment of diseases, including infectious diseases, cardiovascular disease, and cancer. It provides pharmacological evidence, such as the latest information related to efficacy and safety data, in vitro and in vivo studies, clinical trials, and more, to illustrate the use of these spices and vegetables as both palliative and alternative treatments with the goal of furthering research in this area to produce safer and more effective drugs.

Temas relacionados