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Elsevier

Libros en Ciencias de la Vida

  • Genes, Environment and Alzheimer's Disease

    • 1 Edición
    • Orly Lazarov + 1 más
    • Inglés
    Genes, Environment and Alzheimer's Disease discusses the role that activities such as exercise can play in cardiovascular health, while also highlighting the fact that the last 10 years have brought great discoveries in the strong environmental component of brain disorders, neurodegeneration, and cognitive decline. It is now clear that brain insult is an environmental risk factor for AD, while on the other hand, lifestyle components such as exercise and level of education may play a protective role, delaying the onset and/or severity of the disease. Evidence from experiments in rodent models of Alzheimer’s disease contributes major insight into the molecular mechanisms by which the environment plays its role in AD. Additionally, there are diseases related to lifestyle that may lead to AD. This volume reviews new discoveries related to all these factors, serving as a translational tool for clinicians and researchers interested in genetic and environmental risk factors for the disease.

  • Tumor Immunology

    • 1 Edición
    • Volumen 130
    • Inglés
    Advances in Immunology, a long-established and highly respected publication, presents current developments as well as comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, including molecular and cellular activation mechanisms, phylogeny and molecular evolution, and clinical modalities. Edited and authored by the foremost scientists in the field, each volume provides up-to-date information and directions for the future. This volume focuses on tumor immunology.

  • Chemokines

    • 1 Edición
    • Volumen 570
    • Inglés
    Chemokines, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in chemokines, and includes sections on such topics as chemokine detection using receptors, tracking cellular responses to chemokines, recognition of GAG-bound chemokines, and the production of chemokine receptor complexes for structural and biophysical studies.

  • Epi-Informatics

    Discovery and Development of Small Molecule Epigenetic Drugs and Probes
    • 1 Edición
    • Jose Medina-Franco
    • Inglés
    Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes.

  • Nanotechnology Tools for the Study of RNA

    • 1 Edición
    • Volumen 139
    • Inglés
    This volume of Progress in Molecular Biology and Translational Science introduces emerging strategies of studying RNA structure and function using nanotechnological tools. The volume aims to provide the readers with a novel view and give them opportunities to think about how to incorporate the new technologies into their own research.

  • Advances in Genetics

    • 1 Edición
    • Volumen 93
    • Inglés
    Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

  • Industrial Oil Crops

    • 1 Edición
    • Thomas McKeon + 3 más
    • Inglés
    Industrial Oil Crops presents the latest information on important products derived from seed and other plant oils, their quality, the potential environmental benefit, and the latest trends in industrial uses. This book provides a comprehensive view of key oil crops that provide products used for fuel, surfactants, paints and coatings, lubricants, high-value polymers, safe plasticizers and numerous other products, all of which compete effectively with petroleum-derived products for quality and cost. Specific products derived from oil crops are a principle concern, and other fundamental aspects of developing oil crops for industrial uses are also covered. These include improvement through traditional breeding, and molecular, tissue culture and genetic engineering contributions to breeding, as well as practical aspects of what is needed to bring a new or altered crop to market. As such, this book provides a handbook for developing products from renewable resources that can replace those currently derived from petroleum. Led by an international team of expert editors, this book will be a valuable asset for those in product research and development as well as basic plant research related to oil crops.

  • Pharmacological Mechanisms and the Modulation of Pain

    • 1 Edición
    • Volumen 75
    • Inglés
    Pharmacological Mechanisms and the Modulation of Pain, the newest volume in the Advances in Pharmacology series, presents the pharmacological mechanisms and the modulation of pain. With a variety of chapters and the best authors in the field, this volume is an essential resource for pharmacologists, immunologists, and biochemists alike.

  • The Diverse Faces of Bacillus Cereus

    • 1 Edición
    • Vincenzo Savini
    • Inglés
    The Diverse Faces of Bacillus cereus elucidates all characteristics of this microorganism, from its environmental and ecologic relevance, to its veterinary involvement, its clinical settings, most common B. cereus associated food poisoning episodes, and the newest airway disease pictures mimicking the inhalation of anthrax. Due to its environmental distribution, B. cereus may cause serious, even fatal human diseases. The organism shows many diverse faces, as it is not only a veterinary pathogen, but also used as a biocontrol agent to control vegetable decay due to its natural antimicrobial properties. Once considered as a mere colonizer or contaminant, Bacillus cereus is nowadays acquiring increasing importance as an agent of nosocomial infections. The book's target audience is familiar with this opportunistic pathogen and will benefit from this clear compendium on the classical and molecular techniques and procedures that may be adopted or followed to correctly identify this intriguing multi-faceted microorganism.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 94
    • Inglés
    Published since 1959, Advances in Applied Microbiology continues to be one of the most widely read and authoritative review sources in microbiology. The series contains comprehensive reviews of the most current research in applied microbiology, and includes recent research on the roles of fungal communities in soil nutrient recycling, the microbial nitrogen cycle in soil, and the inter-kingdom associations between soil bacteria, fungi, and mycorrhizal fungi.

  • Ion Channels as Therapeutic Targets, Part A

    • 1 Edición
    • Volumen 103
    • Inglés
    Ion Channels as Therapeutic Targets is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 323
    • Inglés
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

  • Hsp90 in Cancer: Beyond the Usual Suspects

    • 1 Edición
    • Volumen 129
    • Inglés
    Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression.

  • Molecules to Medicine with mTOR

    Translating Critical Pathways into Novel Therapeutic Strategies
    • 1 Edición
    • Kenneth Maiese
    • Inglés
    Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous throughout the body and has a critical role in gene transcription and protein formation, stem cell development, cell survival and senescence, aging, immunity, tissue regeneration and repair, metabolism, tumorigenesis, oxidative stress, and pathways of programmed cell death that include apoptosis and autophagy. Incorporating a translational medicine approach, this important reference highlights the basic cellular biology of mTOR pathways, presents the role of mTOR during normal physiologic function and disease, and illustrates how the mechanisms of mTOR can be targeted for current and future therapeutic treatment strategies. Coverage of mTOR signaling includes the entire life cycle of cells that impacts multiple systems of the body including those of nervous, cardiovascular, immune, musculoskeletal, endocrine, reproductive, renal, and respiratory origin.

  • Thin Film Coatings for Biomaterials and Biomedical Applications

    • 1 Edición
    • Hans J Griesser
    • Inglés
    Thin Film Coatings for Biomaterials and Biomedical Applications discusses the latest information on coatings, including their historic use by scientists who are looking to improve the properties and biological responses of the material-host interface. Thin films, in particular, are becoming more widely researched and used as an alternative to traditional sprayed coatings because they have a more uniform structure and therefore greater stability. This book provides readers with a comprehensive guide to thin film coatings and their application in the biomaterials field. Part One of the book details the fundamentals of thin films for biomedical application, while Part Two looks at the special properties of thin films, with a final section reviewing functional thin films and their usage in biomedical applications.

  • Clinical Trials

    Study Design, Endpoints and Biomarkers, Drug Safety, and FDA and ICH Guidelines
    • 2 Edición
    • Tom Brody
    • Inglés
    Clinical Trials, Second Edition, offers those engaged in clinical trial design a valuable and practical guide. This book takes an integrated approach to incorporate biomedical science, laboratory data of human study, endpoint specification, legal and regulatory aspects and much more with the fundamentals of clinical trial design. It provides an overview of the design options along with the specific details of trial design and offers guidance on how to make appropriate choices. Full of numerous examples and now containing actual decisions from FDA reviewers to better inform trial design, the 2nd edition of Clinical Trials is a must-have resource for early and mid-career researchers and clinicians who design and conduct clinical trials.

  • Methods of Hydrobiology

    (Freshwater Biology)
    • 1 Edición
    • Jürgen Schwoerbel
    • Inglés
    Methods of Hydrobiology discusses the study of life of organism in water. It also discusses the science of inland waters, called limnology. The focuses of learning are animals, plants, and bacteria that live in water. The main object of the book is to review and evaluate the methods utilised to gather data on the characteristics of water dwellers. The topics of bacteriology are also covered. The fields of bacteriology that will be covered are hydrobacteriology, hydrobotany, and hydrozoology. The means of measurement and calculation applied by production biology are discussed. The text begins with a discussion of the types of water and their description. This is followed by a qualitative analysis of the phytoplankton. A separate chapter is devoted to the means for running water investigation. Another section of the book focuses on the procedures in the biological evaluation of underground water. The book will provide useful information to marine biologist, botanist, zoologist, microbiologist, students, and researches in the field of biological sciences.

  • Collaborative Genomics Projects: A Comprehensive Guide

    • 1 Edición
    • Margi Sheth + 2 más
    • Inglés
    Collaborative Genomics Projects: A Comprehensive Guide contains operational procedures, policy considerations, and the many lessons learned by The Cancer Genome Atlas Project. This book guides the reader through methods in patient sample acquisition, the establishment of data generation and analysis pipelines, data storage and dissemination, quality control, auditing, and reporting. This book is essential for those looking to set up or collaborate within a large-scale genomics research project. All authors are contributors to The Cancer Genome Atlas (TCGA) Program, a NIH- funded effort to generate a comprehensive catalog of genomic alterations in more than 35 cancer types. As the cost of genomic sequencing is decreasing, more and more researchers are leveraging genomic data to inform the biology of disease. The amount of genomic data generated is growing exponentially, and protocols need to be established for the long-term storage, dissemination, and regulation of this data for research. The book's authors create a complete handbook on the management of research projects involving genomic data as learned through the evolution of the TCGA program, a project that was primarily carried out in the US, but whose impact and lessons learned can be applied to international audiences.

  • The Innate Immune Response to Noninfectious Stressors

    Human and Animal Models
    • 1 Edición
    • Massimo Amadori
    • Inglés
    The Innate Immune Response to Non-infectious Stressors: Human and Animal Models highlights fundamental mechanisms of stress response and important findings on how the immune system is affected, and in turn affects such a response. In addition, this book covers the crucial link between stress response and energy metabolism, prompts a re-appraisal of some crucial issues, and helps to define research priorities in this fascinating, somehow elusive field of investigation.

  • Chemosensory Transduction

    The Detection of Odors, Tastes, and Other Chemostimuli
    • 1 Edición
    • Frank Zufall + 1 más
    • Inglés
    Written by leaders in the field of chemosensation, Chemosensory Transduction provides a comprehensive resource for understanding the molecular mechanisms that allow animals to detect their chemical world. The text focuses on mammals, but also includes several chapters on chemosensory transduction mechanisms in lower vertebrates and insects. This book examines transduction mechanisms in the olfactory, taste, and somatosensory (chemesthetic) systems as well as in a variety of internal sensors that are responsible for homeostatic regulation of the body. Chapters cover such topics as social odors in mammals, vertebrate and invertebrate olfactory receptors, peptide signaling in taste and gut nutrient sensing. Includes a foreword by preeminent olfactory scientist Stuart Firestein, Chair of Columbia University’s Department of Biological Sciences in New York, NY. Chemosensory Transduction describes state-of-the-art approaches and key findings related to the study of the chemical senses. Thus, it serves as the go-to reference for this subject for practicing scientists and students with backgrounds in sensory biology and/or neurobiology. The volume will also be valuable for industry researchers engaged in the design or testing of flavors, fragrances, foods and/or pharmaceuticals.

  • Intracellular Consequences of Amyloid in Alzheimer's Disease

    • 1 Edición
    • Michael R. D'Andrea
    • Inglés
    Consequences of Intracellular Amyloid in Alzheimer’s Disease addresses one of the more currently unresolved aspects confounding Alzheimer’s research, the significance of intraneuronal amyloid. It seeks to explain some of the unresolved questions concerning intracellular amyloid and its origin, entry, and toxicity. Following up on Dr. D’Andrea’s first book, Bursting Neurons and Fading Memories: An Alternative Hypothesis for the Pathogenesis of Alzheimer’s Disease, this book further examines the Inside-Out or Bursting alternative hypothesis of how amyloid escapes the circulatory system to ultimately enter neurons, also examining whether there is a relationship between intracellular amyloid, amyloid plaques, and cognitive impairment. Through a comprehensive explanation of the currently relevant scientific research on intracellular amyloid compiled in this handy reference, readers will better understand the mechanisms that lead to neuron death.

  • Pharmacy Practice in Developing Countries

    Achievements and Challenges
    • 1 Edición
    • Ahmed Fathelrahman + 2 más
    • Inglés
    Pharmacy Practice in Developing Countries: Achievements and Challenges offers a detailed review of the history and development of pharmacy practice in developing countries across Africa, Asia, and South America. Pharmacy practice varies substantially from country to country due to variations in needs and expectations, culture, challenges, policy, regulations, available resources, and other factors. This book focuses on each country’s strengths and achievements, as well as areas of weakness, barriers to improvement and challenges. It sets out to establish a baseline for best practices, taking all of these factors into account and offering solutions and opportunities for the future. This book is a valuable resource for academics, researchers, practicing pharmacists, policy makers, and students involved in pharmacy practice worldwide as it provides lessons learned on a global scale and seeks to advance the pharmacy profession.

  • Electronic Noses and Tongues in Food Science

    • 1 Edición
    • Maria Luz Rodriguez Mendez
    • Inglés
    Electronic Noses and Tongues in Food Science describes the electronic products of advanced chemical and physical sciences combined with intuitive integration of microprocessors, advanced bioinformatics and statistics. These include, for example, voltammetric, bio-electronic, piezoelectric platforms made from a variety of components including, nanoparticles, enzyme biosensors, heavy metals, graphite-epoxy composites, metal oxide semiconductors, microelectrodes, microfluidic channels, pre-manufactured gas sensors, redox enzymes and others and is an ideal resource for understanding and utilizing their power in Food Science settings. Devices used to analyse one particular food item can theoretically be adapted for other food items or components. This does not just mean the re-deploying the physical platforms but also the mode of bioinformatic and statistical analysis. This includes artificial neural networks (ANN), linear discriminant analysis (LDA), partial least squares (PLS), principal component analysis (PCA) etc. In other words, there is cross transference of chemistry, physics, concepts, techniques, findings and approaches from one food to another. Electronic noses and tongues are two of these devices but are advancing in application and importance. This book provides examples of the use of electronic noses and tongues to characterise components that contribute to sensory or compositional profiles, from ripening to harvesting and from storage of raw materials to packaging and consumption. These devises are suitable for high-throughput analysis, quality control or to determine the nature and extent of spoilage and adulteration, and have also been used to ascertain the geographical origins of food and mixtures.

  • Ionic Liquids in Lipid Processing and Analysis

    Opportunities and Challenges
    • 1 Edición
    • Xuebing Xu + 2 más
    • Inglés
    This book serves as a reference for those interested in state-of-the-art research on the science and technology of ionic liquids (ILs), particularly in relation to lipids processing and analysis. Topics include a review of the chemistry and physics of ILs as well as a quantitative understanding of structure-activity relationships at the molecular level. Further, chapter authors examine the molecular basis of the toxicity of ILs, the prediction of the properties of ILs, and the rationale and steps toward a priori design of ionic liquids for task-defined applications. Emerging research in developing lipid-inspired ILs and their prospective use in drug formulation is described. Among the highlights are the latest advances in IL-mediated biocatalysis and biotransformation, along with lipase production, purification, and activation.

  • Essential Clinically Applied Anatomy of the Peripheral Nervous System in the Head and Neck

    • 1 Edición
    • Paul Rea
    • Inglés
    Essential Clinically Applied Anatomy of the Nerves in the Head and Neck presents the reader with an easy access format to clinically-applied peripheral nervous system (PNS) anatomy. Perfect for a quick reference to essential details. The chapters review nerves of the head and neck, the origin(s), course, distribution and relevant pathologies affecting each are given, where relevant. The pathologies present typical injuries to the nerves of the PNS, as well as clinical findings on examination and treatments. It details modern clinical approaches to the surgery and other treatments of these nerve pathologies, as applicable to the clinical scenario.

  • The Membranes of Cells

    • 3 Edición
    • Philip L. Yeagle
    • Inglés
    The Membranes of Cells, Third Edition, provides a basic guide to biomembranes, connecting researchers to the numerous fields of biology. The new edition offers a complete update of content based on new understandings in the field. Foundational content for graduate students, researchers, professors, and undergraduate students across the sciences is provided, succinctly covering all of the basic information needed for lipids and membranes.

  • Fundamental Statistical Principles for the Neurobiologist

    A Survival Guide
    • 1 Edición
    • Stephen W. Scheff
    • Inglés
    Fundamental Statistical Principles for Neurobiologists introduces readers to basic experimental design and statistical thinking in a comprehensive, relevant manner. This book is an introductory statistics book that covers fundamental principles written by a neuroscientist who understands the plight of the neuroscience graduate student and the senior investigator. It summarizes the fundamental concepts associated with statistical analysis that are useful for the neuroscientist, and provides understanding of a particular test in language that is more understandable to this specific audience, with the overall purpose of explaining which statistical technique should be used in which situation. Different types of data are discussed such as how to formulate a research hypothesis, the primary types of statistical errors and statistical power, followed by how to actually graph data and what kinds of mistakes to avoid. Chapters discuss variance, standard deviation, standard error, mean, confidence intervals, correlation, regression, parametric vs. nonparametric statistical tests, ANOVA, and post hoc analyses. Finally, there is a discussion on how to deal with data points that appear to be "outliers" and what to do when there is missing data, an issue that has not sufficiently been covered in literature.

  • Social Aspects of Drug Discovery, Development and Commercialization

    • 1 Edición
    • Odilia Osakwe + 1 más
    • Inglés
    Social Aspects of Drug Discovery, Development and Commercialization provides an insightful analysis of the drug discovery and development landscape as it relates to society. This book examines the scientific, legal, philosophical, economic, political, ethical and cultural factors that contribute to drug development. The pharmaceutical industry is under scrutiny to develop safer and more effective drugs in a quicker and more affordable manner. Recent criticism and debates have emphasized varying opinions on the issues concerning the drug discovery and development process. This book provides thoughtful and valuable discussions and analysis of the social challenges and potential opportunities through all stages of the pharmaceutical process, from inception through marketing. With a unique focus on the social factors that increasingly play a role in how drug development is planned, structured, and executed throughout the drug product lifecycle, this is an essential resource for students, professors, and researchers who seek a better understanding of the interface between the pharmaceutical industry, health care systems, and society.

  • Making a Scientific Case for Conscious Agency and Free Will

    • 1 Edición
    • William R. Klemm
    • Inglés
    Making a Scientific Case for Conscious Agency and Free Will makes a series of arguments that certain human behaviors are impossible to explain in the absence of free will, and that free will emerges from materialistic processes of brain function. It outlines future directions for neuroscience studies that can harness emerging technologies and tools for systems-level analysis. All humans have the sensation that they consciously will certain things to happen and that, in the absence of external constraints, they are free to choose from among alternatives. This notion of free will is deemed obvious by the average person based on common experience. Free will is frequently defended with arguments stemming from social, legal, philosophical, and religious perspectives. But these arguments appeal to consequences—not causes—of choices and decisions. In the past 3 decades, debate has raged within the scientific community over whether free will is in fact an illusion. Because free will would require conscious agency, the supporting corollary is that consciousness itself cannot do anything and is merely an observer rather than an actor.

  • Studies in Natural Products Chemistry

    • 1 Edición
    • Volumen 47
    • Inglés
    Studies in Natural Products Chemistry contains the latest articles written by leading authorities in their respective fields of research, presenting current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is an invaluable resource for anyone working in natural product and medicinal chemistry.

  • Metabolic Phenotyping in Personalized and Public Healthcare

    • 1 Edición
    • Jeremy Nicholson + 3 más
    • Inglés
    Metabolic Phenotyping in Personalized and Public Healthcare provides information on the widespread recognition that a personalized or stratified approach to patient treatment may offer a more efficient and effective healthcare solution than phenotype-led approaches.In order to achieve that objective, a deep personal description is required at the level of the genome, proteome, metabolome, or preferably a combination of these aided by technology. This book, edited and written by the outstanding luminaries of this evolving field, evaluates metabolic profiling and its uses across personalized and population healthcare, while also covering the advent of new technology fields, such as surgical metabonomics. In addition, the text presents specific examples of where this technology has been used clinically and with efficacy, pointing towards a framework and protocol for usage as it hits the clinical mainstream.

  • Biomaterials Nanoarchitectonics

    • 1 Edición
    • Mitsuhiro Ebara
    • Inglés
    Biomaterials Nanoarchitectonics, written from the perspectives of authors form NIMS and other researchers worldwide, provides readers with an explanation of the theory and techniques of nanoarchitectonics, exploring its applications in biomedical fields, including regenerative medicine, drug delivery, and diagnostic and treatment systems based on pathogenic mechanisms. The book also explains the use of nanomaterials that enable 'materials therapy', in which the materials themselves elicit a sustainable, curative effect from living tissue.

  • Graduate Research

    A Guide for Students in the Sciences
    • 4 Edición
    • Robert V. Smith + 2 más
    • Inglés
    Graduate Research is an all-in-one resource for prospective and matriculated graduate students in the sciences. The newly revised edition includes updates to every chapter. Graduate Research covers a range of topics including writing and preparation of research proposals, developing and refining teaching skills, and ethics and compliance areas such as research involving human subjects and animals. Graduate Research helps readers navigate the multidimensional and interdisciplinary world of scientific research and it is an invaluable resource for graduate researchers as well as those in advising or mentoring roles.

  • Complications in Neuroanesthesia

    • 1 Edición
    • Hemanshu Prabhakar
    • Inglés
    Complications in Neuroanesthesia focuses on complications that may arise related to neuroanesthesia practice and discusses its various causes. Each complication is written as a separate chapter, and the pathophysiology and mechanisms of each complication, as well as measures for diagnosis, treatment and prevention are discussed. Towards the end of the book, several case scenarios are provided to the readers that challenge readers to diagnose the possible complication for each case. Chapters include brain and spinal cord problems, cardiovascular and hematological problems, and nerve and muscle problems. Written in a standard format, Complications in Neuroanesthesia provides quick and easy access to understanding problems in neuroanesthesia. It provides insight into all possible complications occurring during perioperative management of neurosurgical and neurologic patients. It is useful for trainees, clinicians, and researchers in the fields of neurosurgery, neurocritical care, and neurology by providing an understanding of preventable mishaps that may occur in neurosurgical or neurologic patients.

  • Carigie's Neuroanatomy of the Rat

    • 1 Edición
    • Wolfgang Zeman
    • Inglés

  • Biochemical Immunological Pharmacology

    Proceedings of the 8th International Congress of Pharmacology, Tokyo, 1981
    • 1 Edición
    • H. Yoshida + 2 más
    • Inglés
    Advances in Pharmacology & Therapeutics II, Volume 4: Biochemical Immunological Pharmacology covers papers on the developments in pharmacology and therapeutics. The book contains invited lectures on the effect of drugs on immunological control mechanisms; the pharmacology of specific, pure and potent serotonin 5-HT2 or S2-antagonists; and the pharmacology of phospholipases A2 isolated from snake venoms. The text also contains papers on leukotrienes; the guanine nucleotide-binding regulatory component of adenylate cyclase; and the pharmacological and toxicological implications of multiple cytochromes P-450. The impact of the emerging biotechnologies on pharmacology; the action of antipsychotics on LSD-induced neurochemical and behavioral effects in rats; and the effect of histamine and related compounds on the immune response are also considered. The book also presents papers on inflammation; prostacyclin; prostaglandins; and chemical hazards to humans.

  • Genetic Counselling

    • 2 Edición
    • Alan Carruth Stevenson + 1 más
    • Inglés
    Genetic Counselling, Second Edition covers genetic counseling, which is mainly concerned with advising people about the risk that a member of a family will suffer from a congenital or hereditary disorder. This edition updates topics such as the advent of differential staining of chromosomes and extensive use of amniocentesis and other techniques in pre-natal diagnosis. When considering defects and disorders, an attempt is made to indicate where risk estimates should present no problems to the practicing physician, and where, by reason of genetical, statistical, or diagnostic complexities, it may be advisable to seek some specialist opinion. This book concentrates on such estimations of risk, emphasizing that pre-requisites for adequate estimations of risks are as accurate a diagnosis as possible. The mechanisms of inheritance of the trait or availability of data on which to base empirical estimates are also deliberated. This publication is intended as a guide to clinicians and as an aide-memoire to medical geneticists.

  • Growth Hormone in Health and Disease

    • 1 Edición
    • Volumen 138
    • Inglés
    This volume of Progress in Molecular Biology and Translational Science focuses on the growth hormone in health and disease.

  • Ecofriendly Pest Management for Food Security

    • 1 Edición
    • Omkar
    • Inglés
    Ecofriendly Pest Management for Food Security explores the broad range of opportunity and challenges afforded by Integrated Pest Management systems. The book focuses on the insect resistance that has developed as a result of pest control chemicals, and how new methods of environmentally complementary pest control can be used to suppress harmful organisms while protecting the soil, plants, and air around them. As the world’s population continues its rapid increase, this book addresses the production of cereals, vegetables, fruits, and other foods and their subsequent demand increase. Traditional means of food crop production face proven limitations and increasing research is turning to alternative means of crop growth and protection.

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 55
    • Inglés
    Progress in Medicinal Chemistry provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a new era for Chagas Disease drug discovery? and imaging in drug development.

  • Neuroimaging Personality, Social Cognition, and Character

    • 1 Edición
    • John R Absher + 1 más
    • Inglés
    Neuroimaging Personality, Social Cognition, and Character covers the science of combining brain imaging with other analytical techniques for use in understanding cognition, behavior, consciousness, memory, language, visual perception, emotional control, and other human attributes. Multidimensional brain imaging research has led to a greater understanding of character traits such as honesty, generosity, truthfulness, and foresight previously unachieved by quantitative mapping. This book summarizes the latest brain imaging research pertaining to character with structural and functional human brain imaging in both normal individuals and those with brain disease or disorder, including psychiatric disorders.By reviewing and synthesizing the latest structural and functional brain imaging research related to character, this book situates itself into the larger framework of cognitive neuroscience, psychiatric neuroimaging, related fields of research, and a wide range of academic fields, such as politics, psychology, medicine, education, law, and religion.

  • Vitamin D Hormone

    • 1 Edición
    • Volumen 100
    • Inglés
    First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on vitamin D hormone.

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 322
    • Inglés
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology, and includes articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

  • Personalized Medicine

    • 1 Edición
    • Volumen 102
    • Inglés
    The Advances in Protein Chemistry and Structural Biology series is an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • Protein: The Basis of All Life

    • 1 Edición
    • J. E. R. McDonagh
    • Inglés
    Protein: The Basis of All Life examines the relationship between pulsatory cycles and metabolic cycles happening inside a protein. This book discusses the process of photosynthesis, the production of glycosides, and the importance of fat-soluble and water-soluble vitamins. The introductory chapters deal with the process of anaerobic glycosis; factors involved in the aerobic glycolysis; steps in the citric acid cycle; description of glucose resynthesis; description of the method of transamination; process involved in the production of fats; features of steroids synthesis; and source of nitrogen compounds. The subsequent chapters consider the components of nucleotides, the contents of porphyrin compounds, and the reproductive cycle. The mechanisms of the inflammation-cancer cycle are presented. The concluding chapters are devoted to the chemotherapeutic remedies to be derived from the integrated endocrine glandular system. The book can provide useful information to doctors, endocrinologists, students, and researchers.

  • Receptors

    Proceedings of the 7th International Congress of Pharmacology, Paris, 1978
    • 1 Edición
    • J. Jacob
    • Inglés
    Advances in Pharmacology and Therapeutics, Volume l: Receptors contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of receptors, their pharmacology, and their therapeutic applications. Topics covered range from opiate receptors and their endogenous ligands to membrane receptors in eukaryotic cells. Applications of binding to pharmacological research are also discussed. This volume is comprised of 29 chapters and opens with an overview of the chemistry and biochemistry of pituitary endorphins, paying particular attention to the correlation between the analgesic potency, receptor binding properties, preferred solution conformation, and metabolic stability of natural and synthetic opioid peptides. The reader is then introduced to the biosynthesis and release of the enkephalins; opiate receptors and their endogenous ligands; denervation supersensitivity in skeletal muscle; and biochemistry and physiology of dopaminergic and beta-adrenergic receptors in mammalian central nervous system. The following chapters explore the role of guanylnucleotides in the regulation of hormonally stimulated adenylate cyclase; interactions of cholera toxin with cell membranes; problems in studying hormone receptor binding; and the mechanism of action of anti-hormones. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.

  • The Agro-Technological System towards 2000

    A European Perspective
    • 1 Edición
    • Volumen 174
    • G. Antonelli + 1 más
    • Inglés
    The research published here constitutes a profound reflection on what is taking place in the world of agriculture at the threshold of the year 2000. The book attempts to go beyond a narrow sectoral analysis of the primary sector. It sets out to focus instead on the dynamic and innovative aspects of the agrotechnological system constituted by the complex interdependence of the agro-production, agro-food, agro-industrial and agro-ecological subsystems. The authors, internationally renowned scholars and scientists, tackle the most pressing contemporary economics issues from both a theoretical and policy-making standpoint. Three different lines of research are pursued concerning, first, the evolution and trends of world and European agricultural production, second, agricultural surplus formation and productivity dynamics in the economies of industrialized countries, and, lastly, the destination of agricultural outputs and land allotment under the impact of agro-bio-technologie...

  • The Prostaglandins

    Pharmacological and Therapeutic Advances
    • 1 Edición
    • M. F. Cuthbert
    • Inglés
    The Prostaglandins: Pharmacological and Therapeutic Advances provides a concise account of the more important theoretical developments and areas in which the prostaglandins are being introduced into clinical practice or have potential clinical application. Chapters I to IV of this book deal with the chemistry and classification, distribution and metabolism, general pharmacology, and mechanism of action. The rest of the chapters discuss the relationship of the prostaglandins to the reproductive, cardiovascular, respiratory, and gastro-intestinal systems with an emphasis on the human pharmacology and potential therapeutic applications. This text also includes the speculations and suggestions of contributors regarding the possible and further use of the prostaglandins. This publication is a good reference for biochemists and medical students concerned with the potential of prostaglandins.

  • The Role of Water in Agriculture

    Based on Papers and Discussions at a Symposium Held at the Welsh Plant Breeding Station Near Aberystwyth on March 19th, 1969
    • 1 Edición
    • James A. Taylor
    • Inglés
    The Role of Water in Agriculture focuses on the role of water in British agriculture. This book discusses the growing importance of hydrological science and agricultural hydrology. Organized into 14 chapters, this book begins with an overview of the problems of accurate rainfall measurement and its importance to agriculture. This text then presents a comprehensive study of the sources of error in agricultural water budgets. Other chapters consider the progress reports on two catchment studies and a report on the effect of agricultural treatments on water availability in the soil. This book discusses as well the sediment yields from forested and agricultural lands on an international basis. The final chapter deals with a summary of the discussions with conclusions and implications. This book is a valuable resource for hydrologists, geographers, meteorologists, agricultural scientists, applied biologists, plant physiologists, and pedologists. Engineers, administrators, and advisers will also find this book useful.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 136
    • Inglés
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich and varied and exemplary of the abundant subject matter addressed by this long-running serial.

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