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Elsevier

Libros en Ciencias de la Vida

  • Computational Neurostimulation

    • 1 Edición
    • Volumen 222
    • Inglés
    Computational Neurostimulation, the latest volume in the Progress in Brain Research series provides an introduction to a nascent field with contributions from leading researchers. In addition, it addresses a very timely and relevant issue which has long been known to require more treatment.

  • Computational Immunology

    Models and Tools
    • 1 Edición
    • Josep Bassaganya-Riera
    • Inglés
    Computational Immunology: Models and Tools encompasses the methodological framework and application of cutting-edge tools and techniques to study immunological processes at a systems level, along with the concept of multi-scale modeling. The book's emphasis is on selected cases studies and application of the most updated technologies in computational modeling, discussing topics such as computational modeling and its usage in immunological research, bioinformatics infrastructure, ODE based modeling, agent based modeling, and high performance computing, data analytics, and multiscale modeling. There are also modeling exercises using recent tools and models which lead the readers to a thorough comprehension and applicability. The book is a valuable resource for immunologists, computational biologists, bioinformaticians, biotechnologists, and computer scientists, as well as all those who wish to broaden their knowledge in systems modeling.

  • New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System – Part B

    • 1 Edición
    • Volumen 221
    • Inglés
    New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System - Part B is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.

  • Biodiversity of the Southern Ocean

    • 1 Edición
    • Bruno David + 1 más
    • Inglés
    The Southern Ocean surrounding the Antarctic continent is vast, in particular, its history, its isolation, and climate, making it a unique "laboratory case" for experimental evolution, adaptation and ecology. Its evolutionary history of adaptation provide a wealth of information on the functioning of the biosphere and its potential. The Southern Ocean is the result of a history of nearly 40 million years marked by the opening of the Straits south of Australia and South America and intense cooling. The violence of its weather, its very low temperatures, the formation of huge ice-covered areas, as its isolation makes the Southern Ocean a world apart. This book discusses the consequences for the evolution, ecology and biodiversity of the region, including endemism, slowed metabolism, longevity, gigantism, and its larval stages; features which make this vast ocean a "natural laboratory" for exploring the ecological adaptive processes, scalable to work in extreme environmental conditions. Today, biodiversity of the Southern Ocean is facing global change, particularly in regional warming and acidification of water bodies. Unable to migrate further south, how will she cope, if any, to visitors from the North?

  • Epigenetic Gene Expression and Regulation

    • 1 Edición
    • Suming Huang + 2 más
    • Inglés
    Epigenetic Gene Expression and Regulation reviews current knowledge on the heritable molecular mechanisms that regulate gene expression, contribute to disease susceptibility, and point to potential treatment in future therapies. The book shows how these heritable mechanisms allow individual cells to establish stable and unique patterns of gene expression that can be passed through cell divisions without DNA mutations, thereby establishing how different heritable patterns of gene regulation control cell differentiation and organogenesis, resulting in a distinct human organism with a variety of differing cellular functions and tissues. The work begins with basic biology, encompasses methods, cellular and tissue organization, topical issues in epigenetic evolution and environmental epigenesis, and lastly clinical disease discovery and treatment. Each highly illustrated chapter is organized to briefly summarize current research, provide appropriate pedagogical guidance, pertinent methods, relevant model organisms, and clinical examples.

  • Food Fraud

    • 1 Edición
    • John M. Ryan
    • Inglés
    Food Fraud provides an overview of the current state on the topic to help readers understand which products are being impacted, how pervasive food fraud is, and what laws are in effect across the developed world. As international food trade increases, food processors, distributors, and consumers are purchasing more and more food from foreign countries that, in many cases, have inadequate oversight or control over what is coming into our supermarkets, restaurants, and refrigerators. This book is an essential quick reference that will familiarize readers with the latest issues surrounding the food industry.

  • Nicotine Use in Mental Illness and Neurological Disorders

    • 1 Edición
    • Volumen 124
    • Inglés
    Nicotine Use in Mental Illness and Neurological Disorders, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into nicotine use in mental illness and neurological disorders. It reviews current knowledge and understanding, also provides a starting point for researchers and practitioners entering the field.

  • Nutritional Composition of Fruit Cultivars

    • 1 Edición
    • Monique Simmonds + 1 más
    • Inglés
    Nutritional Composition of Fruit Cultivars provides readers with the latest information on the health related properties of foods, making the documentation of the nutritive value of historical cultivars especially urgent, especially before they are lost and can't be effectively compared to modern cultivars. Because there is considerable diversity and a substantial body of the compositional studies directed towards commercial varieties, this information is useful for identifying traits and features that may be transposed from one variety to another. In addition, compositional and sensory features may also be used for commercialization and to characterize adulteration. Detailed characterization of cultivars can be used to identify "super-foods". Alternatively, unmasked historical cultivars may be the focus of reinvigorated commercial practices. Each chapter in this book has sections on the botanical aspects, the composition of traditional or ancient cultivars, the composition of modern cultivars, a focus on areas of research, the specialty of the communicating author of each chapter, and summary points.

  • Molecular Mechanisms that Orchestrate the Assembly of Antigen Receptor Loci

    • 1 Edición
    • Volumen 128
    • Inglés
    Molecular Mechanisms That Orchestrate the Assembly of Antigen Receptor Loci, the latest volume in the Advances in Immunology series focuses on the generation of an effective immune response to invading pathogens As B and T lymphocytes are characterized by the expression of antigen receptors that specifically recognize determinants expressed on pathogens, this volume discusses how antigen receptors are synthesized in B and T lymphocytes.

  • Meyler's Side Effects of Drugs

    The International Encyclopedia of Adverse Drug Reactions and Interactions
    • 16 Edición
    • Jeffrey K. Aronson
    • Inglés
    Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Sixteenth Edition, Seven Volume Set builds on the success of the 15 previous editions, providing an extensively reorganized and expanded resource that now comprises more than 1,500 individual drug articles with the most complete coverage of adverse reactions and interactions found anywhere. Each article contains detailed and authoritative information about the adverse effects of each drug, with comprehensive references to the primary literature, making this a must–have reference work for any academic or medical library, pharmacologist, regulatory organization, hospital dispensary, or pharmaceutical company. The online version of the book provides an unparalleled depth of coverage and functionality by offering convenient desktop access and enhanced features such as increased searchability, extensive internal cross-linking, and fully downloadable and printable full-text, HTML or PDF articles.

  • Essential Chemistry for Formulators of Semisolid and Liquid Dosages

    • 1 Edición
    • Vitthal S. Kulkarni + 1 más
    • Inglés
    A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosit... microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations.

  • Genetic Control of Malaria and Dengue

    • 1 Edición
    • Zach N. Adelman
    • Inglés
    Genetic Control of Malaria and Dengue focuses on the knowledge, technology, regulation and ethics of using genetically modified mosquitoes to interrupt the transmission of important vector-borne diseases including Malaria. It contains coverage of the current state of knowledge of vector-borne diseases and how they are currently controlled; vaccine, drug and insecticide development; various strategies for altering the genome of mosquitoes in beneficial ways; and the regulatory, ethical and social environment concerning these strategies. For more than five decades, the prospect of using genetically-modified mosquitoes to control vector-borne disease transmission has been a purely hypothetical scenario. We simply did not have the technology or basic knowledge to be able to do it. With the explosion of field trials and potential interventions in development, Genetic Control of Malaria and Dengue provides a comprehensive overview of research in genetics, microbiology, virology, and ecology involved in the development and implementation of genetic modification programs for virus and disease control. This book is meant to provide a practical guide to researchers, regulators and the general public about how this technology actually works, how it can be improved, and what is still unknown.

  • Artificial Neural Network for Drug Design, Delivery and Disposition

    • 1 Edición
    • Munish Puri + 4 más
    • Inglés
    Artificial Neural Network for Drug Design, Delivery and Disposition provides an in-depth look at the use of artificial neural networks (ANN) in pharmaceutical research. With its ability to learn and self-correct in a highly complex environment, this predictive tool has tremendous potential to help researchers more effectively design, develop, and deliver successful drugs. This book illustrates how to use ANN methodologies and models with the intent to treat diseases like breast cancer, cardiac disease, and more. It contains the latest cutting-edge research, an analysis of the benefits of ANN, and relevant industry examples. As such, this book is an essential resource for academic and industry researchers across the pharmaceutical and biomedical sciences.

  • Shoulder and Elbow Trauma and its Complications

    Volume 2: The Elbow
    • 1 Edición
    • Michael Greiwe
    • Inglés
    Shoulder and Elbow Trauma and Its Complications: Volume 2: The Elbow provides an update on elbow surgery, a type of procedure that is seeing a significant increase in recent years. Although some of these surgeries are due to an aging population, a large proportion of operations are being performed on younger patients who have damaged their joints through physical activity. Worldwide, many of the injuries sustained through sport and physical activity are fractures which can be difficult to treat and can cause complications. Chapters in this detailed book will look at the most common types of elbow trauma and how to manage complications in surgery.

  • Mushroom Biotechnology

    Developments and Applications
    • 1 Edición
    • Marian Petre
    • Inglés
    Mushroom Biotechnology: Developments and Applications is a comprehensive book to provide a better understanding of the main interactions between biological, chemical and physical factors directly involved in biotechnological procedures of using mushrooms as bioremediation tools, high nutritive food sources, and as biological helpers in healing serious diseases of the human body. The book points out the latest research results and original approaches to the use of edible and medicinal mushrooms as efficient bio-instruments to reduce the environment and food crises. This is a valuable scientific resource to any researcher, professional, and student interested in the fields of mushroom biotechnology, bioengineering, bioremediation, biochemistry, eco-toxicology, environmental engineering, food engineering, mycology, pharmacists, and more.

  • Human Physiology, Biochemistry and Basic Medicine

    • 1 Edición
    • Laurence A. Cole + 1 más
    • Inglés
    Human Physiology, Biochemistry and Basic Medicine is a unique perspective that draws together human biology, physiology, biochemistry, nutrition, and cell biology in one comprehensive volume. In this way, it is uniquely qualified to address the needs of the emerging field of humanology, a holistic approach to understanding the biology of humans and how they are distinguished from other animals. Coverage starts with human anatomy and physiology and the details of the workings of all parts of the male and female body. Next, coverage of human biochemistry and how sugars, fats, and amino acids are made and digested is discussed, as is human basic medicine, covering the science of diseases and human evolution and pseudo-evolution. The book concludes with coverage of basic human nutrition, diseases, and treatments, and contains broad coverage that will give the reader an understanding of the entire human picture.

  • Biology and Evolution of the Mexican Cavefish

    • 1 Edición
    • Alex Keene + 2 más
    • Inglés
    Biology and Evolution of the Mexican Cavefish features contributions by leading researchers in a comprehensive, unique work that examines a number of distinct areas of biology—evolution, development, ecology, and behavior—using the Mexican cavefish as a powerful model system to further understanding of basic biological processes such as eye degeneration, hearing, craniofacial development, sleep, and metabolic function. These fish are currently being used to better understand a number of issues related to human health, including age-related blindness, sleep, obesity, mood-related disorders, and aging. The recent sequencing of the cavefish genome broadens the interest of this system to groups working with diverse biological systems, and has helped researchers identify genes that regulate sleep, eye degeneration, and metabolic function. Mexican cavefish are particularly powerful for the study of biological processes because these fish evolved independently in twenty-nine caves in the Sierra de el Abra Region of Northeast Mexico. These fish have dramatic adaptations to the cave environment, and this can be used to identify genes involved in disease-related traits. This scholarly text will be of interest to researchers and students throughout diverse areas of biology and ecology. It includes photographs of animals and behavior in laboratory and natural settings that will also increase interest and accessibility to non-experts.

  • Epigenomics in Health and Disease

    • 1 Edición
    • Mario Fraga + 1 más
    • Inglés
    Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications to the genetic material of human cells. With coverage pertinent to both basic biology and translational research, the book will be of particular interest for medical and bioscience researchers and students seeking current translational knowledge in epigenesis and epigenomics. Coverage includes the latest findings on epigenome-wide research in disease-based profiling, epidemiological implications, epigenome-wide epigenetic studies, the cancer epigenome, and other pervasive disease categories.

  • Advances in Molecular Toxicology

    • 1 Edición
    • Volumen 9
    • Inglés
    Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.

  • The Epigenome and Developmental Origins of Health and Disease

    • 1 Edición
    • Cheryl S. Rosenfeld
    • Inglés
    Winner of 2016 BMA Medical Award for Basic and Clinical Sciences The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples.

  • Genetic Diagnosis of Endocrine Disorders

    • 2 Edición
    • Roy E. Weiss + 1 más
    • Inglés
    Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias.

  • Aquafeed Formulation

    • 1 Edición
    • Sergio F Nates
    • Inglés
    Aquafeed Formulation is the only resource that provides summaries with examples and formulation techniques specifically to meet the needs of anyone in the aquaculture industry. As feed is the largest single cost item in aquaculture production, and formulating aquaculture feed requires many combinations of several ingredients and nutrient requirements, this book takes a clear-and -concise approach, providing essential information on formulation and covering relevant available software, feed nutrients, and additives such as enzymes and phytase and conjugated fatty acids, as well as best industry practices to improve aquafeed production. Users will find this to be a one-stop resource for anyone interested or involved in, the global aquaculture industry.

  • Emotions, Technology, Design, and Learning

    • 1 Edición
    • Sharon Y. Tettegah + 1 más
    • Inglés
    Emotions, Technology, Design, and Learning provides an update to the topic of emotional responses and how technology can alter what is being learned and how the content is learned. The design of that technology is inherently linked to those emotional responses. This text addresses emotional design and pedagogical agents, and the emotions they generate. Topics include design features such as emoticons, speech recognition, virtual avatars, robotics, and adaptive computer technologies, all as relating to the emotional responses from virtual learning.

  • The Neuronal Codes of the Cerebellum

    • 1 Edición
    • Detlef Heck
    • Inglés
    The Neuronal Codes of the Cerebellum provides the most updated information on what is known on the topics of the cerebellum’s anatomy and single cell physiology, two areas where there has been a gap in knowledge regarding the specific codes it uses to process information internally and convey commands to other brain regions. This has created difficulties for researchers and clinicians looking to develop an understanding of the mechanisms by which it contributes to behavior and how its dysfunction causes neurological symptoms. Focused on findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes, this edited volume will aid scientists in overcoming that knowledge gap, also serving as the first resource to broadly address the different aspects of spike coding in the cerebellum that focuses on spike train analysis.

  • Biomechanics and Motor Control

    Defining Central Concepts
    • 1 Edición
    • Mark L. Latash + 1 más
    • Inglés
    Biomechanics and Motor Control: Defining Central Concepts provides a thorough update to the rapidly evolving fields of biomechanics of human motion and motor control with research published in biology, psychology, physics, medicine, physical therapy, robotics, and engineering consistently breaking new ground. This book clarifies the meaning of the most frequently used terms, and consists of four parts, with part one covering biomechanical concepts, including joint torques, stiffness and stiffness-like measures, viscosity, damping and impedance, and mechanical work and energy. Other sections deal with neurophysiological concepts used in motor control, such as muscle tone, reflex, pre-programmed reactions, efferent copy, and central pattern generator, and central motor control concepts, including redundancy and abundance, synergy, equilibrium-point hypothesis, and motor program, and posture and prehension from the field of motor behavior. The book is organized to cover smaller concepts within the context of larger concepts. For example, internal models are covered in the chapter on motor programs. Major concepts are not only defined, but given context as to how research came to use the term in this manner.

  • New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System Part A

    • 1 Edición
    • Volumen 220
    • Inglés
    New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.

  • Pharmaceutical Microbiology

    Essentials for Quality Assurance and Quality Control
    • 1 Edición
    • Tim Sandle
    • Inglés
    Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control presents that latest information on protecting pharmaceutical and healthcare products from spoilage by microorganisms, and protecting patients and consumers. With both sterile and non-sterile products, the effects can range from discoloration to the potential for fatality. The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.

  • Statistics for Food Scientists

    Making Sense of the Numbers
    • 1 Edición
    • Frank Rossi + 1 más
    • Inglés
    The practical approached championed in this book have led to increasing the quality on many successful products through providing a better understanding of consumer needs, current product and process performance and a desired future state. In 2009, Frank Rossi and Viktor Mirtchev brought their practical statistical thinking forward and created the course “Statistics for Food Scientists”. The intent of the course was to help product and process developers increase the probability of their project’s success through the incorporation of practical statistical thinking in their challenges. The course has since grown and has become the basis of this book.

  • Phase Transitions in Foods

    • 2 Edición
    • Yrjo H Roos + 1 más
    • Inglés
    Phase Transitions in Foods, Second Edition, assembles the most recent research and theories on the topic, describing the phase and state transitions that affect technological properties of biological materials occurring in food processing and storage. It covers the role of water as a plasticizer, the effect of transitions on mechanical and chemical changes, and the application of modeling in predicting stability rates of change. The volume presents methods for detecting changes in the physical state and various techniques used to analyze phase behavior of biopolymers and food components. It should become a valuable resource for anyone involved with food engineering, processing, storage, and quality, as well as those working on related properties of pharmaceuticals and other biopolymers.

  • Apoptosis and Development

    • 1 Edición
    • Volumen 114
    • Inglés
    Apoptosis and Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila.

  • Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part A

    • 1 Edición
    • Volumen 563
    • Inglés
    Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part A & B, are the latest volumes in the Methods in Enzymology series, continuing the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods centered on the use of Electron Paramagnetic Resonance (EPR) techniques to study biological structure and function.

  • Plant Factory

    An Indoor Vertical Farming System for Efficient Quality Food Production
    • 1 Edición
    • Toyoki Kozai + 2 más
    • Inglés
    Plant Factory: An Indoor Vertical Farming System for Efficient Quality Food Production provides information on a field that is helping to offset the threats that unusual weather and shortages of land and natural resources bring to the food supply. As alternative options are needed to ensure adequate and efficient production of food, this book represents the only available resource to take a practical approach to the planning, design, and implementation of plant factory (PF) practices to yield food crops. The PF systems described in this book are based on a plant production system with artificial (electric) lights and include case studies providing lessons learned and best practices from both industrial and crop specific programs. With insights into the economics as well as the science of PF programs, this book is ideal for those in academic as well as industrial settings.

  • A Practical Guide to Rational Drug Design

    • 1 Edición
    • Sun Hongmao
    • Inglés
    This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors’ active compounds or from natural ligands of the targets; how to springboard from competitors’ SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes.

  • Molecular Microbial Diagnostic Methods

    Pathways to Implementation for the Food and Water Industries
    • 1 Edición
    • Nigel Cook + 2 más
    • Inglés
    Molecular Microbial Diagnostic Methods: Pathways to Implementation for the Food and Water Industry was developed by recognized and experienced highlevel scientists. It’s a comprehensive and detailed reference that uncovers industry needs for the use of molecular methods by providing a brief history of water and food analysis for the pathogens of concern. It also describes the potential impact of current and cutting-edge molecular methods. This book discusses the advantages of the implementation of molecular methods, describes information on when and how to use specific methods, and presents why one should utilize them for pathogen detection in the routine laboratory. The content is also pertinent for anyone carrying out microbiological analysis at the research level, and for scientists developing methods, as it focuses on the requirements of end-users.

  • Endoscopic Diagnosis and Treatment in Urethral Pathology

    Handbook of Endourology
    • 1 Edición
    • Petrisor Aurelian Geavlete
    • Inglés
    Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format.Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

  • Concepts and Models for Drug Permeability Studies

    Cell and Tissue based In Vitro Culture Models
    • 1 Edición
    • Bruno Sarmento
    • Inglés
    This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

  • Prostate Cancer

    Science and Clinical Practice
    • 2 Edición
    • Jack H. Mydlo + 1 más
    • Inglés
    Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical trials.

  • Essential Oils in Food Preservation, Flavor and Safety

    • 1 Edición
    • Victor R. Preedy
    • Inglés
    Essential Oils in Food Preservation, Flavor and Safety discusses the major advances in the understanding of the Essential Oils and their application, providing a resource that takes into account the fact that there is little attention paid to the scientific basis or toxicity of these oils. This book provides an authoritative synopsis of many of the complex features of the essential oils as applied to food science, ranging from production and harvesting, to the anti-spoilage properties of individual components. It embraces a holistic approach to the topic, and is divided into two distinct parts, the general aspects and named essential oils. With more than 100 chapters in parts two and three, users will find valuable sections on botanical aspects, usage and applications, and a section on applications in food science that emphasizes the fact that essential oils are frequently used to impart flavor and aroma. However, more recently, their use as anti-spoilage agents has been extensively researched.

  • Bioengineering for Surgery

    The Critical Engineer Surgeon Interface
    • 1 Edición
    • Walid Farhat + 1 más
    • Inglés
    Bioengineering is the application of engineering principles to address challenges in the fields of biology and medicine encompassing the principles of engineering design to the full spectrum of living systems. In surgery, recent advances in minimal invasive surgery and robotics are the culmination of the work that both engineers and surgeons have achieved in the medical field through an exciting and challenging interface. This interface rests on the medical curiosity and engineering solutions that lead eventually to collaboration and development of new ideas and technologies. Most recently, innovation by surgeons has become a fundamental contribution to medical research in the surgical field, and it is through effective communication between surgeons and biomedical engineers and promoting collaborative initiatives that translational research is possible. Bioengineering for Surgery explores this interface between surgeons and engineers and how it leads to innovation processes, providing clinical results, fundraising and prestige for the academic institution. This book is designed to teach students how engineers can fit in with their intended environment and what type of materials and design considerations must be taken into account in regards to medical ideas.

  • Integrated Management of Salt Affected Soils in Agriculture

    Incorporation of Soil Salinity Control Methods
    • 1 Edición
    • Nesreen Houssein Ahmen Abou-Baker + 1 más
    • Inglés
    Integrated Management of Salt Affected Soils in Agriculture is a concise guide to evaluating and addressing soil issues related to saline content. Methods focused, the book combines agricultural and soil-based insights to efficiently remediate salt-affected soil. Environmental stress conditions such as salinity have a devastating impact on plant growth and yield, causing considerable loss to agricultural production worldwide. Soil salinity control prevents soil degradation by salinization and reclaim already saline soils. This book will help develop the proper management procedures, to solve problems of crop production on salt-affected soils.

  • Breeding Oilseed Crops for Sustainable Production

    Opportunities and Constraints
    • 1 Edición
    • Surinder Kumar Gupta
    • Inglés
    Breeding Oilseed Crops for Sustainable Production: Opportunities and Constraints presents key insights into accelerating the breeding of sustainable and superior varieties. The book explores the genetic engineering/biotechn... that has played a vital role in transforming economically important traits from distant/wild species to cultivated varieties, enhancing the quality and quantity of oil and seed yield production. Integrated nutrient management, efficient water management, and forecasting models for pests diseases outbreaks and integrated pest and pest management have also added new dimensions in breeding for sustainable production. With the rise in demand, the scientific community has responded positively by directing a greater amount of research towards sustainable production both for edible and industrial uses. Covering the latest information on various major world oil crops including rapeseed mustard, sunflower, groundnut, sesame, oilpalm, cotton, linseed/flax, castor and olive, this book brings the latest advances together in a single volume for researchers and advanced level students.

  • Biomineralization and Biomaterials

    Fundamentals and Applications
    • 1 Edición
    • Conrado Aparicio + 1 más
    • Inglés
    Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance.

  • Advances in Genetics

    • 1 Edición
    • Volumen 91
    • Inglés
    Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing furture directions.

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 319
    • Kwang W. Jeon
    • Inglés
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

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    • 1 Edición
    • Volumen 71
    • Inglés
    Advances in Clinical Chemistry, Volume 71, is the latest installment in this internationally acclaimed series. This latest volume contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions

    • 1 Edición
    • Volumen 100
    • Inglés
    Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions continues the tradition of the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • Performance Psychology

    Perception, Action, Cognition, and Emotion
    • 1 Edición
    • Markus Raab + 4 más
    • Inglés
    This book integrates findings from across domains in performance psychology to focus on core research on what influences peak and non-peak performance. The book explores basic and applied research identifying cognition-action interactions, perception-cognition interactions, emotion-cognition interactions, and perception-action interactions. The book explores performance in sports, music, and the arts both for individuals and teams/groups, looking at the influence of cognition, perception, personality, motivation and drive, attention, stress, coaching, and age. This comprehensive work includes contributions from the US, UK, Canada, Germany, and Australia.

  • Virus as Populations

    Composition, Complexity, Dynamics, and Biological Implications
    • 1 Edición
    • Esteban Domingo
    • Inglés
    Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere.

  • Analytical Ultracentrifugation

    • 1 Edición
    • Volumen 562
    • Inglés
    Analytical Ultracentrifugation, the latest volume in Methods in Enzymology, focuses on analytical ultracentrifugation. The scope of this technique has greatly expanded in recent years due to advances in instrumentation, algorithms and software. This volume describes the latest innovations in the field and in the applications of analytical ultracentrifugation in the analysis of macromolecules, macromolecular assemblies, and biopharmaceuticals.

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    Bioactive Foods in Health Promotion
    • 1 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion reviews and presents new hypotheses and conclusions on the effects of different bioactive components of probiotics, prebiotics, and synbiotics to prevent disease and improve the health of various populations. Experts define and support the actions of bacteria; bacteria modified bioflavonoids and prebiotic fibrous materials and vegetable compounds. A major emphasis is placed on the health-promoting activities and bioactive components of probiotic bacteria.

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