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Elsevier

Libros en Ciencias de la Vida

  • Human Physiology, Biochemistry and Basic Medicine

    • 1 Edición
    • Laurence A. Cole + 1 más
    • Inglés
    Human Physiology, Biochemistry and Basic Medicine is a unique perspective that draws together human biology, physiology, biochemistry, nutrition, and cell biology in one comprehensive volume. In this way, it is uniquely qualified to address the needs of the emerging field of humanology, a holistic approach to understanding the biology of humans and how they are distinguished from other animals. Coverage starts with human anatomy and physiology and the details of the workings of all parts of the male and female body. Next, coverage of human biochemistry and how sugars, fats, and amino acids are made and digested is discussed, as is human basic medicine, covering the science of diseases and human evolution and pseudo-evolution. The book concludes with coverage of basic human nutrition, diseases, and treatments, and contains broad coverage that will give the reader an understanding of the entire human picture.

  • Biology and Evolution of the Mexican Cavefish

    • 1 Edición
    • Alex Keene + 2 más
    • Inglés
    Biology and Evolution of the Mexican Cavefish features contributions by leading researchers in a comprehensive, unique work that examines a number of distinct areas of biology—evolution, development, ecology, and behavior—using the Mexican cavefish as a powerful model system to further understanding of basic biological processes such as eye degeneration, hearing, craniofacial development, sleep, and metabolic function. These fish are currently being used to better understand a number of issues related to human health, including age-related blindness, sleep, obesity, mood-related disorders, and aging. The recent sequencing of the cavefish genome broadens the interest of this system to groups working with diverse biological systems, and has helped researchers identify genes that regulate sleep, eye degeneration, and metabolic function. Mexican cavefish are particularly powerful for the study of biological processes because these fish evolved independently in twenty-nine caves in the Sierra de el Abra Region of Northeast Mexico. These fish have dramatic adaptations to the cave environment, and this can be used to identify genes involved in disease-related traits. This scholarly text will be of interest to researchers and students throughout diverse areas of biology and ecology. It includes photographs of animals and behavior in laboratory and natural settings that will also increase interest and accessibility to non-experts.

  • Epigenomics in Health and Disease

    • 1 Edición
    • Mario Fraga + 1 más
    • Inglés
    Epigenomics in Health and Disease discusses the next generation sequencing technologies shaping our current knowledge with regards to the role of epigenetics in normal development, aging, and disease. It includes the consequences for diagnostics, prognostics, and disease-based therapies made possible by the study of the complete set of epigenetic modifications to the genetic material of human cells. With coverage pertinent to both basic biology and translational research, the book will be of particular interest for medical and bioscience researchers and students seeking current translational knowledge in epigenesis and epigenomics. Coverage includes the latest findings on epigenome-wide research in disease-based profiling, epidemiological implications, epigenome-wide epigenetic studies, the cancer epigenome, and other pervasive disease categories.

  • Advances in Molecular Toxicology

    • 1 Edición
    • Volumen 9
    • Inglés
    Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.

  • The Epigenome and Developmental Origins of Health and Disease

    • 1 Edición
    • Cheryl S. Rosenfeld
    • Inglés
    Winner of 2016 BMA Medical Award for Basic and Clinical Sciences The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples.

  • Genetic Diagnosis of Endocrine Disorders

    • 2 Edición
    • Roy E. Weiss + 1 más
    • Inglés
    Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias.

  • Aquafeed Formulation

    • 1 Edición
    • Sergio F Nates
    • Inglés
    Aquafeed Formulation is the only resource that provides summaries with examples and formulation techniques specifically to meet the needs of anyone in the aquaculture industry. As feed is the largest single cost item in aquaculture production, and formulating aquaculture feed requires many combinations of several ingredients and nutrient requirements, this book takes a clear-and -concise approach, providing essential information on formulation and covering relevant available software, feed nutrients, and additives such as enzymes and phytase and conjugated fatty acids, as well as best industry practices to improve aquafeed production. Users will find this to be a one-stop resource for anyone interested or involved in, the global aquaculture industry.

  • Emotions, Technology, Design, and Learning

    • 1 Edición
    • Sharon Y. Tettegah + 1 más
    • Inglés
    Emotions, Technology, Design, and Learning provides an update to the topic of emotional responses and how technology can alter what is being learned and how the content is learned. The design of that technology is inherently linked to those emotional responses. This text addresses emotional design and pedagogical agents, and the emotions they generate. Topics include design features such as emoticons, speech recognition, virtual avatars, robotics, and adaptive computer technologies, all as relating to the emotional responses from virtual learning.

  • The Neuronal Codes of the Cerebellum

    • 1 Edición
    • Detlef Heck
    • Inglés
    The Neuronal Codes of the Cerebellum provides the most updated information on what is known on the topics of the cerebellum’s anatomy and single cell physiology, two areas where there has been a gap in knowledge regarding the specific codes it uses to process information internally and convey commands to other brain regions. This has created difficulties for researchers and clinicians looking to develop an understanding of the mechanisms by which it contributes to behavior and how its dysfunction causes neurological symptoms. Focused on findings related to the neuronal code used by cerebellar neurons for the representation of behavioral and sensory processes, this edited volume will aid scientists in overcoming that knowledge gap, also serving as the first resource to broadly address the different aspects of spike coding in the cerebellum that focuses on spike train analysis.

  • Biomechanics and Motor Control

    Defining Central Concepts
    • 1 Edición
    • Mark L. Latash + 1 más
    • Inglés
    Biomechanics and Motor Control: Defining Central Concepts provides a thorough update to the rapidly evolving fields of biomechanics of human motion and motor control with research published in biology, psychology, physics, medicine, physical therapy, robotics, and engineering consistently breaking new ground. This book clarifies the meaning of the most frequently used terms, and consists of four parts, with part one covering biomechanical concepts, including joint torques, stiffness and stiffness-like measures, viscosity, damping and impedance, and mechanical work and energy. Other sections deal with neurophysiological concepts used in motor control, such as muscle tone, reflex, pre-programmed reactions, efferent copy, and central pattern generator, and central motor control concepts, including redundancy and abundance, synergy, equilibrium-point hypothesis, and motor program, and posture and prehension from the field of motor behavior. The book is organized to cover smaller concepts within the context of larger concepts. For example, internal models are covered in the chapter on motor programs. Major concepts are not only defined, but given context as to how research came to use the term in this manner.

  • New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System Part A

    • 1 Edición
    • Volumen 220
    • Inglés
    New Trends in Basic and Clinical Research of Glaucoma: A Neurodegenerative Disease of the Visual System is the latest volume from Progress in Brain Research focusing on new trends in basic and clinical research of glaucoma. This established international series examines major areas of basic and clinical research within neuroscience, as well as emerging subfields.

  • Pharmaceutical Microbiology

    Essentials for Quality Assurance and Quality Control
    • 1 Edición
    • Tim Sandle
    • Inglés
    Pharmaceutical Microbiology: Essentials for Quality Assurance and Quality Control presents that latest information on protecting pharmaceutical and healthcare products from spoilage by microorganisms, and protecting patients and consumers. With both sterile and non-sterile products, the effects can range from discoloration to the potential for fatality. The book provides an overview of the function of the pharmaceutical microbiologist and what they need to know, from regulatory filing and GMP, to laboratory design and management, and compendia tests and risk assessment tools and techniques. These key aspects are discussed through a series of dedicated chapters, with topics covering auditing, validation, data analysis, bioburden, toxins, microbial identification, culture media, and contamination control.

  • Statistics for Food Scientists

    Making Sense of the Numbers
    • 1 Edición
    • Frank Rossi + 1 más
    • Inglés
    The practical approached championed in this book have led to increasing the quality on many successful products through providing a better understanding of consumer needs, current product and process performance and a desired future state. In 2009, Frank Rossi and Viktor Mirtchev brought their practical statistical thinking forward and created the course “Statistics for Food Scientists”. The intent of the course was to help product and process developers increase the probability of their project’s success through the incorporation of practical statistical thinking in their challenges. The course has since grown and has become the basis of this book.

  • Phase Transitions in Foods

    • 2 Edición
    • Yrjo H Roos + 1 más
    • Inglés
    Phase Transitions in Foods, Second Edition, assembles the most recent research and theories on the topic, describing the phase and state transitions that affect technological properties of biological materials occurring in food processing and storage. It covers the role of water as a plasticizer, the effect of transitions on mechanical and chemical changes, and the application of modeling in predicting stability rates of change. The volume presents methods for detecting changes in the physical state and various techniques used to analyze phase behavior of biopolymers and food components. It should become a valuable resource for anyone involved with food engineering, processing, storage, and quality, as well as those working on related properties of pharmaceuticals and other biopolymers.

  • Apoptosis and Development

    • 1 Edición
    • Volumen 114
    • Inglés
    Apoptosis and Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila.

  • Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part A

    • 1 Edición
    • Volumen 563
    • Inglés
    Electron Paramagnetic Resonance Investigations of Biological Systems by Using Spin Labels, Spin Probes, and Intrinsic Metal Ions Part A & B, are the latest volumes in the Methods in Enzymology series, continuing the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods centered on the use of Electron Paramagnetic Resonance (EPR) techniques to study biological structure and function.

  • Plant Factory

    An Indoor Vertical Farming System for Efficient Quality Food Production
    • 1 Edición
    • Toyoki Kozai + 2 más
    • Inglés
    Plant Factory: An Indoor Vertical Farming System for Efficient Quality Food Production provides information on a field that is helping to offset the threats that unusual weather and shortages of land and natural resources bring to the food supply. As alternative options are needed to ensure adequate and efficient production of food, this book represents the only available resource to take a practical approach to the planning, design, and implementation of plant factory (PF) practices to yield food crops. The PF systems described in this book are based on a plant production system with artificial (electric) lights and include case studies providing lessons learned and best practices from both industrial and crop specific programs. With insights into the economics as well as the science of PF programs, this book is ideal for those in academic as well as industrial settings.

  • A Practical Guide to Rational Drug Design

    • 1 Edición
    • Sun Hongmao
    • Inglés
    This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors’ active compounds or from natural ligands of the targets; how to springboard from competitors’ SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes.

  • Molecular Microbial Diagnostic Methods

    Pathways to Implementation for the Food and Water Industries
    • 1 Edición
    • Nigel Cook + 2 más
    • Inglés
    Molecular Microbial Diagnostic Methods: Pathways to Implementation for the Food and Water Industry was developed by recognized and experienced highlevel scientists. It’s a comprehensive and detailed reference that uncovers industry needs for the use of molecular methods by providing a brief history of water and food analysis for the pathogens of concern. It also describes the potential impact of current and cutting-edge molecular methods. This book discusses the advantages of the implementation of molecular methods, describes information on when and how to use specific methods, and presents why one should utilize them for pathogen detection in the routine laboratory. The content is also pertinent for anyone carrying out microbiological analysis at the research level, and for scientists developing methods, as it focuses on the requirements of end-users.

  • Endoscopic Diagnosis and Treatment in Urethral Pathology

    Handbook of Endourology
    • 1 Edición
    • Petrisor Aurelian Geavlete
    • Inglés
    Handbook of Endourology contains five focused, review-oriented volumes that are ideal for students and clinicians looking for a comprehensive review rather than a whole course. Each volume is easily accessible through eBook format.Topics covered review both the endourological diagnosis and treatment of prostate, urethral, urinary bladder, upper urinary tract, and renal pathology. All chapters describe the most recent techniques, review the latest results, and analyze the most modern technologies. In the past ten years, the field of endourology has expanded beyond the urinary tract to include all urologic minimally invasive surgical procedures. Recent advancements in robotic and laparoscopic bladder surgery make this one of the fastest moving fields in medicine. As current textbooks are too time-consuming for busy urologists or trainees who also need to learn other areas of urology, this collection provides quick references and over 4000 images that are appropriate for fellows as well as those teaching in the field.

  • Concepts and Models for Drug Permeability Studies

    Cell and Tissue based In Vitro Culture Models
    • 1 Edición
    • Bruno Sarmento
    • Inglés
    This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route.

  • Prostate Cancer

    Science and Clinical Practice
    • 2 Edición
    • Jack H. Mydlo + 1 más
    • Inglés
    Prostate Cancer, Science and Clinical Practice, Second Edition, continues to be an important translational reference that bridges the gap between science and clinical medicine. It reviews the biological processes that can be implicated in the disease, reviews current treatments, highlights the pitfalls where relevant, and examines the scientific developments that might result in future treatments. Key chapters from the previous edition have been updated, and a plethora of new chapters describe new concepts of prostate cancer biology and newly developed therapeutics. Each chapter has been written by internationally recognized specialists on prostate cancer epidemiology, genetic susceptibility, cancer metastases, prostate physiology, proteomics, new therapeutics, and clinical trials.

  • Essential Oils in Food Preservation, Flavor and Safety

    • 1 Edición
    • Victor R. Preedy
    • Inglés
    Essential Oils in Food Preservation, Flavor and Safety discusses the major advances in the understanding of the Essential Oils and their application, providing a resource that takes into account the fact that there is little attention paid to the scientific basis or toxicity of these oils. This book provides an authoritative synopsis of many of the complex features of the essential oils as applied to food science, ranging from production and harvesting, to the anti-spoilage properties of individual components. It embraces a holistic approach to the topic, and is divided into two distinct parts, the general aspects and named essential oils. With more than 100 chapters in parts two and three, users will find valuable sections on botanical aspects, usage and applications, and a section on applications in food science that emphasizes the fact that essential oils are frequently used to impart flavor and aroma. However, more recently, their use as anti-spoilage agents has been extensively researched.

  • Bioengineering for Surgery

    The Critical Engineer Surgeon Interface
    • 1 Edición
    • Walid Farhat + 1 más
    • Inglés
    Bioengineering is the application of engineering principles to address challenges in the fields of biology and medicine encompassing the principles of engineering design to the full spectrum of living systems. In surgery, recent advances in minimal invasive surgery and robotics are the culmination of the work that both engineers and surgeons have achieved in the medical field through an exciting and challenging interface. This interface rests on the medical curiosity and engineering solutions that lead eventually to collaboration and development of new ideas and technologies. Most recently, innovation by surgeons has become a fundamental contribution to medical research in the surgical field, and it is through effective communication between surgeons and biomedical engineers and promoting collaborative initiatives that translational research is possible. Bioengineering for Surgery explores this interface between surgeons and engineers and how it leads to innovation processes, providing clinical results, fundraising and prestige for the academic institution. This book is designed to teach students how engineers can fit in with their intended environment and what type of materials and design considerations must be taken into account in regards to medical ideas.

  • Integrated Management of Salt Affected Soils in Agriculture

    Incorporation of Soil Salinity Control Methods
    • 1 Edición
    • Nesreen Houssein Ahmen Abou-Baker + 1 más
    • Inglés
    Integrated Management of Salt Affected Soils in Agriculture is a concise guide to evaluating and addressing soil issues related to saline content. Methods focused, the book combines agricultural and soil-based insights to efficiently remediate salt-affected soil. Environmental stress conditions such as salinity have a devastating impact on plant growth and yield, causing considerable loss to agricultural production worldwide. Soil salinity control prevents soil degradation by salinization and reclaim already saline soils. This book will help develop the proper management procedures, to solve problems of crop production on salt-affected soils.

  • Breeding Oilseed Crops for Sustainable Production

    Opportunities and Constraints
    • 1 Edición
    • Surinder Kumar Gupta
    • Inglés
    Breeding Oilseed Crops for Sustainable Production: Opportunities and Constraints presents key insights into accelerating the breeding of sustainable and superior varieties. The book explores the genetic engineering/biotechn... that has played a vital role in transforming economically important traits from distant/wild species to cultivated varieties, enhancing the quality and quantity of oil and seed yield production. Integrated nutrient management, efficient water management, and forecasting models for pests diseases outbreaks and integrated pest and pest management have also added new dimensions in breeding for sustainable production. With the rise in demand, the scientific community has responded positively by directing a greater amount of research towards sustainable production both for edible and industrial uses. Covering the latest information on various major world oil crops including rapeseed mustard, sunflower, groundnut, sesame, oilpalm, cotton, linseed/flax, castor and olive, this book brings the latest advances together in a single volume for researchers and advanced level students.

  • Biomineralization and Biomaterials

    Fundamentals and Applications
    • 1 Edición
    • Conrado Aparicio + 1 más
    • Inglés
    Biomineralization is a natural process by which living organisms form minerals in association with organic biostructures to form hybrid biological materials such as bone, enamel, dentine and nacre among others. Scientists have researched the fundamentals of these processes and the unique structures and properties of the resulting mineralized tissues. Inspired by them, new biomaterials for tissue engineering and regenerative medicine have been developed in recent years. Biomineralization and biomaterials: fundamentals and applications looks at the characteristics of these essential processes and natural materials and describes strategies and technologies to biomimetically design and produce biomaterials with improved biological performance.

  • Advances in Genetics

    • 1 Edición
    • Volumen 91
    • Inglés
    Advances in Genetics provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing furture directions.

  • International Review of Cell and Molecular Biology

    • 1 Edición
    • Volumen 319
    • Kwang W. Jeon
    • Inglés
    International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 71
    • Inglés
    Advances in Clinical Chemistry, Volume 71, is the latest installment in this internationally acclaimed series. This latest volume contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions

    • 1 Edición
    • Volumen 100
    • Inglés
    Combined Quantum Mechanical and Molecular Mechanical Modelling of Biomolecular Interactions continues the tradition of the Advances in Protein Chemistry and Structural Biology series has been the essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.

  • Performance Psychology

    Perception, Action, Cognition, and Emotion
    • 1 Edición
    • Markus Raab + 4 más
    • Inglés
    This book integrates findings from across domains in performance psychology to focus on core research on what influences peak and non-peak performance. The book explores basic and applied research identifying cognition-action interactions, perception-cognition interactions, emotion-cognition interactions, and perception-action interactions. The book explores performance in sports, music, and the arts both for individuals and teams/groups, looking at the influence of cognition, perception, personality, motivation and drive, attention, stress, coaching, and age. This comprehensive work includes contributions from the US, UK, Canada, Germany, and Australia.

  • Virus as Populations

    Composition, Complexity, Dynamics, and Biological Implications
    • 1 Edición
    • Esteban Domingo
    • Inglés
    Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere.

  • Analytical Ultracentrifugation

    • 1 Edición
    • Volumen 562
    • Inglés
    Analytical Ultracentrifugation, the latest volume in Methods in Enzymology, focuses on analytical ultracentrifugation. The scope of this technique has greatly expanded in recent years due to advances in instrumentation, algorithms and software. This volume describes the latest innovations in the field and in the applications of analytical ultracentrifugation in the analysis of macromolecules, macromolecular assemblies, and biopharmaceuticals.

  • Probiotics, Prebiotics, and Synbiotics

    Bioactive Foods in Health Promotion
    • 1 Edición
    • Ronald Ross Watson + 1 más
    • Inglés
    Probiotics, Prebiotics, and Synbiotics: Bioactive Foods in Health Promotion reviews and presents new hypotheses and conclusions on the effects of different bioactive components of probiotics, prebiotics, and synbiotics to prevent disease and improve the health of various populations. Experts define and support the actions of bacteria; bacteria modified bioflavonoids and prebiotic fibrous materials and vegetable compounds. A major emphasis is placed on the health-promoting activities and bioactive components of probiotic bacteria.

  • Osteoimmunology

    Interactions of the Immune and Skeletal Systems
    • 2 Edición
    • Joseph Lorenzo + 4 más
    • Inglés
    Osteoimmunology: Interactions of the Immune and Skeletal Systems, Second Edition, explores the advancements that have been made in the field during the last 40 years, including valuable information on our understanding of the interactions between hematopoietic, immune, and bone cells, now known as the field of osteoimmunology. This comprehensive work offers the most extensive summaries of research trends in the field and their translation into new therapeutics. Early chapters deal with the development of osteoblasts, osteoclasts, hematopoietic stem cells, T and B-lymphocytes, and communications between these cellular elements, while later sections contain discussions of the signaling pathways by which RANKL influences osteoclast development and function. Subsequent chapters explore the effects that estrogen has on bone and the immune system, the development of pathologic conditions, and the growing research around osteoporosis, Paget’s disease, the genetics of bone disease, and bone cancer metastasis.

  • Molecular and Cellular Regulation of Adaptation to Exercise

    • 1 Edición
    • Volumen 135
    • Claude Bouchard
    • Inglés
    Molecular Aspects of Exercise Biology and Exercise Genomics, the latest volume in the Progress in Molecular Biology and Translational Science series includes a comprehensive summary of the evidence accumulated thus far on the molecular and cellular regulation of the various adaptations taking place in response to exercise. Changes in the cellular machinery are described for multiple tissues and organs in terms of signaling pathways, gene expression, and protein abundance. Adaptations to acute exercise as well as exposure to regular exercise are also discussed and considered.

  • Kaufman’s Atlas of Mouse Development Supplement

    With Coronal Sections
    • 1 Edición
    • Richard Baldock + 3 más
    • Inglés
    Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 134
    • Inglés
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich and varied and exemplary of the abundant subject matter addressed by this long-running serial.

  • Structure to Function of G Protein-Gated Inwardly Rectifying (GIRK) Channels

    • 1 Edición
    • Volumen 123
    • Inglés
    This volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into GIRK Potassium Channels. It reviews current knowledge and understanding and provides a starting point for researchers and practitioners entering the field.

  • Thermal Imaging Techniques to Survey and Monitor Animals in the Wild

    A Methodology
    • 1 Edición
    • Kirk J Havens + 1 más
    • Inglés
    Thermal Imaging Techniques to Survey and Monitor Animals in the Wild: A Methodology provides a manual for anyone interested in understanding thermal imaging and its usefulness in solving a wide range of problems regarding the observation of wildlife. In the last decade, the cost of thermal imaging technology has significantly decreased, making the equipment more widely available. This book offers an overview of thermal physics and the thermal imager, along with a methodology to optimize the window of opportunity so that wildlife can be observed and studied in their natural habitat. Users will find the knowledge and tools to formulate a sound survey design, with detailed sections on the theory and performance characteristics of thermal imaging cameras utilizing cooled quantum detectors as the sensitive element and additional information on the uncooled micro bolometric imagers which have been introduced into the camera market in past decades. The methodology presented is logical and simple, yet it presents a detailed understanding of the topic and how it applies to the critically interlinked disciplines of biology, physics, micrometeorology, and animal physiology.

  • The Choroid Plexus and Cerebrospinal Fluid

    Emerging Roles in CNS Development, Maintenance, and Disease Progression
    • 1 Edición
    • Josh Neman + 1 más
    • Inglés
    The Choroid Plexus and Cerebrospinal Fluid: Emerging Roles in CNS Development, Maintenance, and Disease Progression combines new and established work to allow for cross-disciplinary discussion and showcase newfound excitement surrounding the choroid plexus and cerebrospinal fluid (CSF). This book is of great utility to neuroscientists interested in biological questions about cancer, multiple sclerosis, Alzheimer’s, choroid plexus, or CSF research, and especially for researchers looking to expand their research into later stages of their disease of interest, such as metastasis. No other resource is currently available which addresses these issues in this fashion. The focus on the choroid plexus provides a practical resource on modeling clinical issues influenced by this brain region for researchers from students to principal investigators.

  • Laboratory Animal Anaesthesia

    • 4 Edición
    • Paul Flecknell
    • Inglés
    Laboratory Animal Anaesthesia, Fourth Edition provides a basic guide to anaesthesia for a very diverse audience needing content, with straight-forward, structured style of writing. Updated with effects of anaesthetics in different laboratory species, including sources of dose rates will be incorporated into tabular material. New information on pain assessment and pain management will be covered, and an increased emphasis on rats and mice for anaesthesia and perioperative care. With newly revised, full color illustrations to facilitate best learning, Laboratory animal Anesthesia, Fourth Edition provides procedures, key points and invaluable advice from a well-known and respected veterinary anesthetist and scientist with over 30 years of experience in the field.

  • Physical-Chemical Properties of Foods

    New Tools for Prediction
    • 1 Edición
    • Aïchatou Musavu Ndob + 2 más
    • Inglés
    The physical and chemical properties of food products have central roles in biotechnology and the pharmaceutical and food industries. Understanding these properties is essential for engineers and scientists to tackle the numerous issues in food processing, including preservation, storage, distribution and consumption.This book discusses models to predict some of the physical-chemical properties (pH, aw and ionic strength) for biological media containing various solutes. In recent years, food production has involved less processing and fewer additives or preservatives. If health benefits for consumers are obvious, it is not only necessary to adapt current processing and preservation processes but also to verify that appropriate technological and health properties are preserved.The authors present established models, but also introduce new tools for prediction with modeling methods that are part of a more general approach to understand the behavior of fluid mixtures and design new products or processes through numerical simulation.

  • Omic Studies of Neurodegenerative Disease - Part B

    • 1 Edición
    • Volumen 122
    • Inglés
    Omic Studies of Neurodegenerative Disease: Part B is part of a well-established international series on neuroscience that examines major areas of basic and clinical research, along with emerging and promising subfields. The book informs the reader on the current state of the studies used to evaluate the mechanisms, causes, and treatment of neurodegeneration through a combination of literature reviews and examples of current research.

  • A Monograph of Codonopsis and Allied Genera (Campanulaceae)

    • 1 Edición
    • De-Yuan Hong
    • Inglés
    Codonopsis and its allied genera, are a group of plants which are important in economy and horticulture. A Monograph of Codonopsis and Allied Genera (Campanulaceae s. str.) offers its audience comprehensive knowledge of these plants including palynology, cytology, population biology, morphological description, geographical distribution with vouchers cited, excellent ink illustrations, and color photos, and keys to genera and to species. This excellent work will facilitate identification of relevant plants, use of plant resources, assessment of endangered states, the development of conservation strategies, and will promote systematic and evolutionary research of this group.

  • Mineral Nutrition of Fruit Trees

    Studies in the Agricultural and Food Sciences
    • 1 Edición
    • D. Atkinson + 2 más
    • Inglés
    Mineral Nutrition of Fruit Trees summarizes the state of knowledge about the mineral nutrition of fruit trees, including peach and apple trees. The discussions are organized around six themes: fruit tree mineral nutrition and crop quality; uptake and transport; effect of soil management and fertilizer applications on nutrient uptake; direct application of nutrients to foliage and fruits; prediction of nutrient requirements; and synthesis. This text consists of 69 chapters and begins with a section dealing with the effects of nutrition on fruit quality. The second section explores the mechanisms of nutrient entry to, and movement within, fruit trees and the means of influencing the nutrition of both the whole tree and the crop by fertilizers and management practices, including irrigation and the use of herbicides. The third section describes methods for predicting the needs of the tree for establishment, growth, and fruit quality. The effects of interactions between nutrition and environment on the mineral composition of fruits are considered, along with an integrated approach to orchard nutrition and bitter pit control, the influence of boron deficiency on fruit quality, and calcium accumulation in apple fruit. This book will be of interest to scientists working in fields such as biochemistry, food technology, agriculture, horticulture, and physiology.

  • Halophytes for Food Security in Dry Lands

    • 1 Edición
    • Muhammad Ajmal Khan + 3 más
    • Inglés
    Halophytes for Food Security in Dry Lands addresses the concerns surrounding global food scarcity, especially focusing on those living in arid and dry lands The book touches on food crises in dry regions of the world and proposes halophytes as an alternate source of consumption for such areas. Halophytes, those plants that thrive in saline soil and provide either food source options themselves, or positively enhance an eco-system’s ability to produce food, and are thus an important and increasingly recognized option for addressing the needs of the nearly 1/6 of the world’s population that lives in these arid and semi-arid climates. Including presentations from the 2014 International Conference on Halophytes for Food Security in Dry Lands, this book features insights from the leading researchers in the subject. It is a valuable resource that includes information on the nutritional value of halophytes, their genetic basis and potential enhancement, adaption of halophytes, and lessons learned thus far.

  • Sex Differences in the Central Nervous System

    • 1 Edición
    • Rebecca M. Shansky
    • Inglés
    Sex Differences in the Central Nervous System offers a comprehensive examination of the current state of sex differences research, from both the basic science and clinical research perspectives. Given the current NIH directive that funded preclinical research must consider both females and males, this topic is of interest to an increasing percentage of the neuroscience research population. The volume serves as an invaluable resource, offering coverage of a wide range of topics: sex differences in cognition, learning, and memory, sex hormone signaling mechanisms, neuroimmune interactions, epigenetics, social behavior, neurologic disease, psychological disorders, and stress. Discussions of research in both animal models and human patient populations are included.

  • Sorting and Recycling Endosomes

    • 1 Edición
    • Volumen 130
    • Inglés
    Sorting and Recycling Endosomes provides the latest information on endosomes, the receiving compartment for endocytosed cargos, and the donor compartment and sorting station for cargos designated to lysosomes, Golgi, or plasma membrane. In recent years, the importance of endosomes as a sorting and recycling compartment has become increasingly appreciated. As such, scientists from various fields of cell biology, membrane traffic, and beyond, see the needs to communicate and learn about the methods used to investigate the dynamics and functions of endosomes. This book brings together specialists from the field who contribute their expertise on a broad range of biomedical topics that will provide ideal reading for researchers interested in endosomal sorting and recycling. This volume covers the approaches necessary to study the key components that mediate the generation and transport of membrane-bounded carriers from the endosomes, and how membrane trafficking machinery is coordinated with cytoskeletons during these processes. In addition to studies carried out in mammalian cells, other model systems such as worm and yeast are also included.

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