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Elsevier

Libros en Ciencias de la Vida

  • Neurobiology and Artificial Intelligence

    Medical, Social and Ethical Implications
    • 1 Edición
    • Luca Saba
    • Inglés
    Neurobiology and Artificial Intelligence: Medical, Social, and Ethical Implicationsexplores the dynamic intersection of neurobiology and artificial intelligence (AI),investigating the scientific, philosophical, and ethical implications of these rapidlyevolving fields. By blending cutting-edge research with thought-provoking discussions,this book aims to make complex topics accessible to an interdisciplinary audience,from researchers and upper graduate students eager to understand how AI andneuroscience shape our understanding of intelligence, creativity, learning, and thehuman condition.

  • Mathematical Modeling and AI-Driven Computational Techniques for Epidemiology and Disease Dynamics

    • 1 Edición
    • Sayooj Aby Jose + 2 más
    • Inglés
    Mathematical Modeling and AI-Driven Computational Techniques for Epidemiology and Disease Dynamics offers a comprehensive exploration of innovative methodologies at the intersection of mathematics, biology, and medicine. This book delves into advanced mathematical modeling, artificial intelligence, and computational intelligence, providing essential tools for understanding and managing complex disease dynamics. Covering a wide range of topics, including fractional-order modeling, optimal control strategies, and privacy-preserving technologies, it addresses critical challenges in public health and healthcare systems. With contributions from leading experts, this volume bridges theoretical advancements and practical applications, making it an invaluable resource for researchers, healthcare professionals, and academics seeking interdisciplinary solutions to global health issues.

  • Agricultural Biostimulants for Mitigation of Salt, Drought, and Heat Stress

    • 1 Edición
    • M. Naeem + 1 más
    • Inglés
    Agricultural Biostimulants for Mitigation of Salt, Drought, and Heat Stress provides up-to-date information on sustainable strategies to enhance the resilience of agricultural crops under adverse environmental conditions. As part of the Biostimulants and Protective Biochemical Agents series, this volume focuses on high-impact challenges and emerging opportunities in crop stress management.Biostimul... represent a promising and effective approach to achieving sustainable agriculture. Widely regarded as renewable sources of plant nutrients, they can enhance crop productivity and improve soil health. Over the past decade, there has been growing interest in the use of diverse biostimulants—includ... plant growth-promoting fungi, rhizobacteria, seaweed extracts, and organic amendments—to increase nutrient use efficiency and boost plant tolerance to abiotic stresses.This book covers a range of key biostimulant categories such as bacteria, algae, plant growth regulators (PGRs), plant growth-promoting bacteria (PGPB), biochar, and other core approaches. It explores how specific biostimulants contribute to protecting and enhancing plant health and is the first comprehensive reference to focus exclusively on their role in safeguarding crop yields under salt, drought, and heat stress conditions.

  • Lipid Nanoparticles-Based mRNA Delivery System

    • 1 Edición
    • Raj Kumar
    • Inglés
    Lipid Nanoparticles-Based mRNA Delivery System offers a comprehensive exploration of lipid nanoparticles (LNPs), the most promising delivery vehicles for mRNA. The book consolidates current knowledge, identifies research gaps, and provides insights into the latest developments in LNP technologies, making it an essential resource for researchers, pharmaceutical developers, and clinicians at the forefront of mRNA therapeutics. Exploring the intricacies of LNP formulation, the book covers a wide range of topics, including the fundamental principles of lipid nanoparticles, design strategies for effective mRNA encapsulation, and the unique challenges associated with various routes of administration—such as intravenous, oral, transdermal, and intranasal delivery.The book also examines the therapeutic applications of lipid-based systems, particularly in vaccines and cancer immunotherapy, while addressing critical challenges like immunogenicity and regulatory considerations. Final sections provide a forward-looking perspective on future trends and innovations in lipid-based mRNA delivery systems, ensuring that readers are well-equipped to navigate this rapidly evolving field.

  • Cutting-Edge Nanocarrier-Based Strategies in the Management of Leukaemia

    • 1 Edición
    • Devesh U. Kapoor + 2 más
    • Inglés
    Cutting-edge Nanocarrier-Based Strategies in the Management of Leukaemia addresses the importance of nanocarriers in leukemia treatment. The book explores advancements in nanotechnology, highlighting therapies like siRNA, miRNA, and gene therapy that improve patient outcomes. Sections provide an introduction to leukemia, covering its epidemiology and risk factors, discuss innovative therapies and the use of various nanocarriers, such as polymeric nanoparticles, liposomes, dendrimers, and hydrogels, and discuss precision medicine, AI in leukemia care, and strategies to overcome treatment resistance. The book is enriched with tables, figures, and images, giving healthcare providers, including physicians, immunologists, oncologists, and pharmacists an invaluable resource on cutting-edge therapies.

  • Plant Proteins, Bioactive Peptides, and Healthy Foods

    Nutritional Properties, Functional Applications, and Processing Innovations
    • 1 Edición
    • Zhongjiang Wang + 4 más
    • Inglés
    Plant Proteins, Bioactive Peptides, and Healthy Foods: Nutritional Properties, Functional Applications, and Processing Innovations offers a comprehensive exploration of emerging and novel plant-based proteins, including soy, pea, walnut, quinoa, hemp, duckweed, oat and more, detailing nutritional properties, bioactive peptide generation, and the potential health benefits they offer for cardiovascular support, muscle recovery, and inflammatory conditions. By analyzing the interactions between proteins and other food components, such as fibers and lipids, the book also highlights the synergies that improve nutrition and digestion. The latest processing technologies, including fermentation and enzymatic hydrolysis, that enhance protein bioavailability are also detailed.Chapter experts highlight the challenges and opportunities in plant-based utilization, including limitations in sensory attributes, processing challenges and allergenicity, strategies for optimizing nutritional quality and functional properties, and future directions in research and industrial applications. Sustainable and efficient plant-protein production is also addressed. This book serves as a valuable guide for professionals in the food industry and researchers looking to innovate functional food products and nutraceuticals, contributing to the growing demand for sustainable, plant-based diets.

  • Episodes in the History of Medical Science

    Discovery Meets Orthodoxy
    • 1 Edición
    • Anthony R. Rees
    • Inglés
    Episodes in the History of Medical Science: Discovery Confronts Orthodoxy highlights key moments in history where scientific and medical advances faced acceptance and rejection by the prevailing orthodoxy. This book places present-day disease protection in context by exploring significant medical and scientific theories, their success stories, challenges, and the frequent resistance to new ideas. It shows how acceptance of scientific discoveries often lags due to conservatism within the scientific community and broader socio-political and cultural influences. The book examines the origins of medical theory and practice, from the revolutionary ideas of Hippocrates and Galen to the rise of Islamic Medicine and the scholasticism of the Middle Ages. It covers the arrival of syphilis in Europe and the ensuing medical debates, the historical battle against smallpox through variolation and vaccination, and the skepticism faced by groundbreaking discoveries in the 19th and 20th centuries. Key topics include the gene debate, the thalidomide tragedy, the antibody revolution, and the paradigm shift in understanding stomach ulcers. The narrative also addresses the modern era's anti-vaccinationism and vaccine hesitancy, emphasizing the ongoing tension between scientific integrity and public acceptance. Episodes in the History of Medical Science: Discovery Confronts Orthodoxy is a valuable resource for medical professionals, researchers, historians, and students. It underscores the importance of scientific and medical integrity, the pursuit of truth, and validated scientific communication. By providing historical insights and examples of perseverance in the face of skepticism, this book offers valuable lessons for improving public health and understanding the dynamic journey of medical science.

  • Translational Cardiothoracic Surgery

    • 1 Edición
    • Adam E.M. Eltorai
    • Inglés
    Translational research is essential to the advancement of medicine. This Cardiothoracic-speci... instructional guide to translational medical research serves as a practical, step-by-step roadmap for taking a biomedical device, potential therapeutic agent, or research question from idea through demonstrated clinical benefit. Fundamentally, the volume aims to help bridge the gap between current research and practice. Written by a team of expert medical, biomedical engineering, and clinical research experts in cardiothoracic surgery, this volume provides a clear process for understanding, designing, executing, and analyzing clinical and translational research within the field.

  • Inmunología

    • 10 Edición
    • David Male + 2 más
    • Español
    Nueva edición de uno de los textos de referencia en inmunología de nuestro portfolio en el que se abordan de forma equilibrada e integrada los conceptos pertenecientes a la inmunología básica y clínica. La estructura general de esta edición de Inmunología es la misma que la de la novena edición, Las secciones 1 y 2 describen el funcionamiento del sistema inmunitario. La sección 3 se ocupa de las respuestas inmunitarias contra los microorganismos patógenos (la función principal del sistema inmunitario), y las secciones 4 a 6 abordan aspectos de inmunología clínica, como las enfermedades autoinmunitarias, la inmunodeficiencia, los trasplantes, la inmunología tumoral y la hipersensibilidad. Todos los capítulos se han actualizado por completo e incluyen numerosos diagramas nuevos. Especial atención merecen los Caps. 17,18,20 y 22 por su profunda actualización en temas relativos a las nuevas vacunas de mRNA, inmunización pasiva, autoinmunidad, nuevos anticuerpos y nuevas terapias celulares y los nuevos descubrimientos a raíz de la epidemia de Covid. Las secciones de razonamiento crítico que siguen a cada capítulo requieren la comprensión del material presentado y de las implicaciones en un entorno de laboratorio o clínico, y sirven como base para el debate en el aula. Otro importante instrumento pedagógico son los resúmenes que recogen los puntos clave de cada capítulo, así como los numerosos esquemas, diagramas y figuras. La nueva edición ofrece contenido adicional online en español a través de la plataforma e-book+. Incluye apartados, tablas y figuras adicionales, así como una colección de 15 videos.

  • Comprehensive Chemistry and Biology of Coumarins Scaffold

    • 1 Edición
    • Shehryar Hameed + 2 más
    • Inglés
    Comprehensive Chemistry and Biology of Coumarins Scaffold covers detailed methods and protocols to synthetize Coumarin derivatives and different applications and future perspectives for these compounds. Coumarin-Based Scaffolds plays an important role in organic, bioorganic, and medicinal chemistry as they act as a bridge between chemistry, life sciences, and biochemical investigations. Coumarin is an important scaffold for designing, generating a wide variety of chemical libraries and drug-like candidates to obtain desired therapeutic and pharmacological properties. Specific functional groups are covered as well as the synthesis of bioactive compounds against specific pathological conditions.The discovery of new coumarin-based drug candidates during the last decades has been covered to assist the pharmaceutical, bioorganic and medicinal chemists for their further research on coumarin-based molecules.

  • Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis

    • 1 Edición
    • Jyotsna Kailashiya
    • Inglés
    Hematological Insights and Clinical Implications of Platelet Functions in Lymphatic Filariasis is a groundbreaking resource that delves into the impact of filarial parasites on platelet functions in humans. This comprehensive work explores the intricate signaling and immunological pathways affected by these interactions, filling a significant gap in the existing literature. The book is particularly valuable for researchers, scientists, and clinicians involved in the management and study of lymphatic filariasis, commonly known as elephantiasis; and also human platelets. With limited prior information on the interplay between human platelets and filarial parasites, this text offers a fresh perspective that could enhance patient management strategies. By understanding these interactions, healthcare professionals may unlock new avenues for effective treatment and prevention of lymphatic filariasis. This book is essential for anyone looking to deepen their understanding of the disease and contribute to its potential elimination.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 118
    • Inglés
    Advances in Food and Nutrition Research, Volume 118 provides the latest advances on nanoformulations that can be used in the food industry, including chapters that cover important topics such as Nanoformulation Used In The Food Industry, Advances in Rapid On-Site Detection Techniques for Food Safety and Authenticity, Utilizing Artificial Intelligence to Enhance Sustainable High-Quality Food Production: Current State, Challenges, and Future Directions, Advances in High Hydrostatic Pressure Processing of Fruit and Vegetable Juicesm Functionality, Health Benefits, and Applications of Fish-Derived Hydrolysates and Peptides, and more.Additional chapters explore Maximizing the utilisation of seafood resources, A novel cooking technique for seafood: sous-vide, and Vegetable oils as a source of omega-3 fatty acids – transgenic vegetable oil.

  • Microglial Aging

    Basic, Translational and Clinical Advances
    • 1 Edición
    • Marie-Eve Tremblay
    • Inglés
    Microglial Aging: Basic, Translational, and Clinical Advances explores groundbreaking research on microglial function in the context of aging. This comprehensive resource delves into the physiological roles of microglia, the effects of aging on their structure and activity, and their significance in age-related neurodegenerative diseases. With insights from basic, translational, and clinical studies, it provides a thorough understanding of microglial health and its impact on aging. The book discusses how lifestyle choices can enhance microglial functions and prevent neurodegenerative diseases. It covers both pharmacological and non-pharmacological approaches, such as the ketogenic diet, cannabinoids, psychedelics, and non-invasive vagal nerve stimulation.This text is invaluable for researchers and clinicians focused on improving the quality of life for an aging population.

  • Mitochondria and Cancer

    From Basic Science to Clinical Applications – Understanding Pathogenesis, Therapy Resistance, and Disease Relapse
    • 1 Edición
    • Farzad Taghizadeh-Hesary + 3 más
    • Inglés
    Mitochondria and Cancer: From Basic Science to Clinical Applications—Underst... Pathogenesis, Therapy Resistance, and Disease Relapse offers comprehensive perspectives about the role of mitochondria in cancer biology and treatment. This book integrates fundamental scientific knowledge with clinical relevance, presenting recent findings that will engage oncology researchers and provide valuable recommendations for cancer prevention and prognosis. In response to the rising global cancer incidence, this book serves as a comprehensive guide to mitochondrial metabolism in oncology, furthering cancer study and management. It explores a wide range of topics that highlight the multifaceted role of mitochondria in cancer, including tumor microenvironment, cancer stem cells, microbiota, resistance mechanisms, mitochondria-enhanci... strategies, and targeted therapies. It includes technical details, research findings, and discussions on the implications of mitochondrial research in cancer treatment and management. Its distinguishing aspects include its comprehensive coverage and diverse perspectives from global experts, providing a well-rounded view of current research.

  • ATP

    From Neurotransmission to Cancer Therapy
    • 1 Edición
    • Ronald Sluyter + 5 más
    • Inglés
    ATP: From Neurotransmission to Cancer Therapy delivers a comprehensive discussion of extracellular ATP biology and its communication role in both homeostasis and pathologic states. It explores the function of ATP across the nervous, sensory, musculoskeletal, cutaneous cardiovascular, pulmonary, gastrointestinal, urinary, reproductive, exocrine, haematopoietic and immune systems. The book considers ATP in the context of various disease states, including cardiovascular, respiratory, psychiatric, inflammatory and neurodegenerative disorders, as well as pain and sensory disorders, infectious diseases, and cancer. ATP in humans is explored alongside other species, including rodents, fish, and plants. This is the latest volume in the “Molecular Mediators in Health and Disease” series. With contributions from specialists across pharmacology, physiology, biophysics, biochemistry, immunology, anatomy, molecular biology, therapeutics, and other critical fields, this volume provides a broad and detailed overview of ATP which will be helpful to researchers working in these areas and beyond.

  • Advances in Agronomy

    • 1 Edición
    • Volumen 196
    • Inglés
    Advances in Agronomy, Volume 196, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Marine Microbial Products

    Applications and Opportunities
    • 1 Edición
    • Sesan Abiodun Aransiola + 2 más
    • Inglés
    Marine Microbial Products: Applications and Opportunities delves into the extensive world of marine microbes, an assemblage of organisms that contain a broad array of bioactive chemicals. Written and edited by a diverse team of environmental microbiologists, this book provides readers with a foundational understanding of marine microbial taxa, the products that may be synthesized from these organisms, technological innovations, and future directions of research. Chapters collate the most current research in healthcare, sustainability, and commercial production, presenting readers with the latest information on antibiotics, antivirals, anticancer therapeutics, immunosuppressive chemicals, bioremediation, food processing, biofertilizers, biopesticides, cosmetics, pigments, probiotics, and functional foods.The book is structured for accessibility to academic and professional audiences, spanning a variety of sectors. It is an indispensable resource for students, professors, researchers, and industry professionals in biology, biotechnology, sustainable development, food, healthcare sciences, and adjacent industries.

  • Immuno-oncology and Immunotherapy Part G

    • 1 Edición
    • Volumen 202
    • Inglés
    Immuno-oncology and Immunotherapy, Part G, Volume 202 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including In situ imaging of pulmonary invariant Natural Killer T cells in precision cut lung slices, Immunofluorescent microscopy to quantify and characterize chromosomal instability, Spatial techniques for understanding the tumor microenvironment, Very high-flex immunophenotyping using co-linear cytofluorometric evaluation, Large-scale CRISPR-Cas9 screens to define regulators of immune checkpoint biology, Assessment of cytoplasmic dsDNA for cellular immunogenicty, and much more.Additional sections cover Harmonization of a multiparametric flow cytometry panel for immunological monitoring on PBMC and whole blood samples: a real-life example, Quantitative assessment of arterial remodeling from confocal microscopy image analysis of the mid-gestation mouse decidua, Phenotypic characterization and function of tumor infiltrating and peripheral B cells in cancer patients, Methodological Advances to analyze Cancer-Associated Fibroblast-derived ECM effects on Macrophage Polarization, and many other topics that will be of interest to readers.

  • Endocrine and Metabolic Emergencies, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 55-1
    • George C. Willis + 1 más
    • Inglés
    In this issue of Emergency Medicine Clinics, guest editors Drs. George Willis and Bennett A. Myers bring their considerable expertise to the topic of Endocrine and Metabolic Emergencies. Endocrine and metabolic emergencies, both those that are commonly encountered in day-to-day emergency medicine and those that are rarely seen, can result in serious complications that can be life-threatening if not recognized, diagnosed, and appropriately managed. In this issue, top experts in the field cover key topics such as diabetic ketoacidosis; hyperosmolar hyperglycemic state; disorders of sodium and potassium; hypoglycemia; and more.

  • Tic Disorders and Tourette Syndrome

    • 1 Edición
    • Volumen 215
    • Christos Ganos + 1 más
    • Inglés
    Tic Disorders and Tourette Syndrome is an essential resource that delves into the clinical aspects, treatments, and ongoing research related to tic disorders and Tourette syndrome. It covers a range of topics from primary to secondary and functional tics, providing differential diagnosis. The book is designed to offer foundational knowledge to neurologists, psychiatrists, neuropsychiatrists, and psychologists, while also catering to the needs of advanced readers. In addition to clinical presentations, the book discusses the epidemiology, etiology, and pathophysiology of tics, along with common neuropsychiatric comorbidities such as obsessive-compulsive disorder, ADHD, mood disorders, and intermittent explosive disorder. The volume also includes treatment options and clinical scales to evaluate tics, illustrated with video accompaniments and animal models.

  • Aquatic Waste Valorization

    Innovative Approaches and Sustainable Strategies
    • 1 Edición
    • Piyush Kashyap + 2 más
    • Inglés
    Aquatic Waste Valorization: Innovative Approaches and Sustainable Strategies is a comprehensive guide for researchers and practitioners in food and environmental sciences, focusing on the critical intersection of waste management and sustainability within the aquatic food industry. The book explores the multifaceted dimensions of aquatic food industry waste, from its chemical composition and economic implications to a thorough introduction of valorization techniques for the use in functional food products and nutraceuticals. It covers emerging methodologies—includ... physical, chemical, and enzymatic processes—as well as approaches such as microbial conversion and nanotechnology, all aimed at transforming waste into valuable resources.In addition, it discusses the recovery of valuable components such as proteins, lipids, and bioactive compounds, highlighting their applications across various industries, including biofuels, bioplastics, and functional food ingredients. Through practical applications, it not only addresses the pressing issue of waste management but also presents innovative strategies to bolster both environmental and economic sustainability. Concluding sections examine global policies and regulations shaping the future of aquatic waste valorization.

  • Connected Diagnoses

    IoT, Healthcare, and Digital Forensics
    • 1 Edición
    • Keshav Kaushik + 1 más
    • Inglés
    Connected Diagnoses: IoT, Healthcare, and Digital Forensics investigates the complex intersection of IoT, healthcare, and digital forensics. The book explores the intricate relationships between these fields, with a focus on cybersecurity, patient data ethics, and challenges in IoT investigations. It advances knowledge on leveraging IoT securely to enhance patient care and digital forensic analysis, providing significant insights from experts along with practical guidance for those operating at the crossroads of these critical disciplines. The book helps professionals grasp, adapt to, and capitalize on the interconnected nature of emerging technologies to ensure ethics, security, and safety. Users will find this to be a comprehensive resource that benefits researchers and practitioners who seek to understand the convergence of medical technology, interconnected devices, and digital forensics.

  • Cushing Syndrome

    History, Diagnosis and Treatment
    • 1 Edición
    • Constantine A. Stratakis
    • Inglés
    Cushing Syndrome: History, Diagnosis, and Treatment is written by top experts on the latest in genetics, molecular advances, and the diagnosis and treatment of Cushing syndrome. The book takes a historical approach to discuss the tremendous and unprecedented research development for this rare condition and includes information on recently approved treatments. It attempts to provide information on most issues surrounding Cushing syndrome and how to deal with its complications, the widening understanding of functional hypercortisolemia and other causes of endogenous cortisol production and its old and new treatment modalities, from pituitary to adrenal tumors, ectopic ACTH production, subclinical, cyclical Cushing syndrome, to aging and metabolic syndrome.The book has a section dedicated to our patients with the patients’ experiences, which will add to the outcome research presented by the physicians. This is a must have reference for scientists and researchers with the latest information in diagnosing and treating this difficult-to-diagnos... and difficult-to-treat condition and gives the clinician, a patient-centric approach to communicate with this particular group of patients.

  • Handbook of Functional Foods

    Techniques, Analytics and Health Benefits
    • 1 Edición
    • Pradeep Kumar + 2 más
    • Inglés
    Handbook of Functional Foods: Techniques, Analytics and Health Benefits provides a comprehensive overview of the extraction and analytical identification techniques of foods’ bioactive components for health and well-being while looking at metabolism, sensory, and safety components. This book reviews, in detail, how functional foods have the potential to drive innovation in the food industry, creating a broad range of healthier and more personalized food options. From emerging extraction and extrusion techniques for the creation of fiber-rich snacks to the synergistic effects of pro- and prebiotics on gut health, readers will come away with an advanced and fresh understanding of necessary insights.

  • Neuroscience-Informed Psychoeducation (NIPE) for Brain and Mental Health

    Part A
    • 1 Edición
    • Volumen 299
    • Inglés
    Neuroscience-Informe... Psychoeducation (NIPE) for Brain and Mental Health series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Brain Energy Metabolism in Alzheimers Disease - Part A

    • 1 Edición
    • Volumen 186
    • Inglés
    International Review of Neurobiology, Volume 186 presents the latest developments in the field, with chapters written by an international board of authors. This volume offers a broad overview of current research and perspectives in neurobiology, serving as a valuable reference for researchers, clinicians, and students interested in understanding advances across diverse areas of the discipline.

  • Molecular Horticulture & Advances in Production System Technology

    • 1 Edición
    • Volumen 117
    • Inglés
    This volume offers a comprehensive overview of cutting-edge developments in horticultural science. This authoritative collection features expert reviews on the molecular genetics and genomics of key species, including faba bean, tomato, celery, lily, and broccoli, elucidating the mechanisms behind yield, quality, and bioactive compounds. The volume also explores innovative and sustainable cultivation techniques, with in-depth analyses of controlled environment agriculture for leafy greens, the use of organic substrates, and the sensory implications of sustainable practices for Brassica oleracea. Crucial insights into the molecular control of pre- and post-harvest traits, this essential text provides researchers, students, and professionals with a forward-looking synthesis of modern horticultural science and its practical applications.

  • Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management

    • 1 Edición
    • Harish Dureja + 5 más
    • Inglés
    Nanotechnology-Based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management explores innovative drug delivery systems utilizing nanotechnology to revolutionize the treatment and management of COPD. By presenting the latest advancements in nanotechnologies—inc... polymeric nanoparticles, liposomes, and theranostic nanoparticles—this volume aims to enhance patient outcomes, alleviate symptoms, and improve lung function, thereby addressing the urgent need for more effective therapies. Structured to cater to a diverse audience, from beginners to advanced researchers, this comprehensive text begins with an overview of COPD, its epidemiology, and current limitations in treatment. The core chapters explore a wide range of nanotechnological applications for diagnosis and disease management, including cutting-edge topics such as nano-immunotherapy and green nanotechnology. Each chapter was developed by a multidisciplinary team of experts from academia and industry, ensuring a comprehensive approach that integrates insights from pharmaceutical sciences, respiratory health, and bioinformatics. Nanotechnology-based Innovations in Chronic Obstructive Pulmonary Disease (COPD) Treatment and Management not only fills a critical gap in COPD literature but also serves as an invaluable resource for researchers, clinicians, and students alike. It promises to be a definitive guide on how innovative drug delivery systems can transform COPD care, paving the way for future advancements in respiratory health management.

  • Design and Applications of Cell-Free Systems Part B

    • 1 Edición
    • Volumen 219
    • Inglés
    Design and Applications of Cell-Free Systems, Part B, Volume 219 offers the latest information on cell free systems for the expression of transmembrane proteins, enzymes, proteins, therapeutics, vaccines, and uses in the biotransformation, translational modification, self-assembly of nano-biomaterials, and in synthetic biology design, challenges, and opportunities. It will help students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners understand cell-free systems and their applications in many areas. The book represents an important component in the field of biochemistry, duly acknowledging the pioneering effort made by Nobel laureate Eduard Buchner for discovery of fermentation in yeast cell extracts (YCE).CFS requires core molecular machinery, including RNA polymerase, translational apparatus (ribosomes, tRNA synthases, and translation factors), energy-generating molecules, and their cofactors, substrates, and DNA or plasmid templates for obtaining desired products. CFS is a simple, rapid, and sensitive platform, which is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired proteins.

  • Natural Product Drug Discovery

    Highly Anticipated Natural Molecules
    • 1 Edición
    • Ning Li + 1 más
    • Inglés
    Natural Product Drug Discovery: Highly Anticipated Natural Molecules, a new volume in the Drug Discovery Opinion series, provides a comprehensive examination of the role of natural products in innovative drug development. The book addresses the significant challenges that highly active natural molecules face in the drug development process, including issues related to bioavailability and potency. Sections present analyses of various classes of natural products, including polysaccharides, volatile oils, and diterpenoids, exploring their chemical properties, biological activities, and potential clinical applications. Each chapter, written by leading experts, offers insights into structural modification techniques, naturally sourced inhibitors, and the application of green biomanufacturing strategies.It will serve as an essential resource for researchers, pharmacologists, and industry professionals involved in natural product drug discovery. Readers will find the necessary information to navigate the complexities of the field, emphasizing the integration of traditional knowledge with modern scientific approaches. Through a thorough understanding of these natural compounds, this book aims to contribute to the advancement of therapeutic innovations in pharmacotherapy.

  • Antibiotic Resistance and Nanotherapy

    • 1 Edición
    • Awanish Kumar + 1 más
    • Inglés
    Antibiotic Resistance and Nanotherapy is a comprehensive guide that explores an interdisciplinary approach to address the pressing issue of antibiotic resistance and explores the possibility of nanotherapy as a cutting-edge strategy to treat illnesses that are resistant to antibiotics, employing nanoparticles to target and kill bacteria selectively without damaging healthy cells. It details the underlying mechanisms of drug resistance in intracellular and extracellular pathogens and explores the latest advancements in nanotechnology, including the development of innovative nanomaterials and delivery systems that can be utilized to combat antibiotic-resistant infections. This book also discusses the ethical and practical challenges associated with implementing nanotherapy for bacterial resistance. Featuring contributions from experts in the field, this book is an essential resource for researchers, medical professionals, and policymakers seeking to understand and tackle the immediate threat posed by antibiotic resistance.

  • How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms

    From Bench to the Clinics
    • 1 Edición
    • Neelam Poonia + 2 más
    • Inglés
    How to Develop Robust Scale-up Strategies for Complex Injectable Dosage Forms: From Bench to the Clinics provides a comprehensive roadmap for transitioning complex injectable formulations from the laboratory to clinical applications. Offering an exploration of various complex injectables, including liposomal dosage forms, nanoparticles, and microspheres, this book delves into dosage form design, excipient selection, stability studies, and optimization techniques. The book examines manufacturing technologies such as aseptic processing, sterile filtration, and lyophilization, and their applications in producing complex injectables. Discussions on quality control measures, analytical techniques, and quality assurance practices are provided to ensure consistent quality and purity throughout the manufacturing process.Readers will benefit from the expert knowledge and practical insights shared by industry professionals and leading researchers, including successful examples of marketed complex injectables. Highlighting best practices and regulatory requirements, this book offers a comprehensive overview of the guidelines for the development, manufacturing, and commercialization of complex injectables. Ideal for pharmaceutical scientists, formulation developers, and regulatory professionals, this book is a valuable resource for anyone involved in the scale-up and commercialization of complex injectable dosage forms.

  • Recent Advances in Bioelectromagnetism and Subtle Energies

    Implications for Health and Disease
    • 1 Edición
    • Jan Martel
    • Inglés
    Recent Advances in Bioelectromagnetism and Subtle Energies: Implications for Health and Disease explores the new findings and emerging concepts in the fields of electromagnetism and human health. This book examines a range of topics from a biophysical and holistic perspective, including the effects of native and manmade electromagnetic fields on living organisms, the role of oxygen in cellular energy production, the intricacies of the human biofield, coherence in cellular and human health, quantum biology phenomena, the history and evolution of electrosensitivity, the development of electromagnetic hygiene, and promising healing modalities. Each chapter provides key insights about the biological effects of electromagnetic fields and their impact on human health and disease development, providing an ideal reference for scientists and readers interested in the recent advances in these areas.

  • Simulating Protein Folding in Variable Environmental Conditions

    Transformation from Globular Proteins to Amyloids
    • 1 Edición
    • Irena Roterman-Konieczna
    • Inglés
    Simulating Protein Folding in Variable Environmental Conditions: Transformation from Globular Proteins to Amyloids delves into the effects of external conditions upon the protein folding process. The book considers how this can lead to amyloid formation and why proteins fold the way they do. It presents the fuzzy oil drop model (FOD-M), which enables the measurements of external factors influencing the folding process and considers changed external conditions as the source for the misfolding process. Sections provide an introduction to amyloid transformation and outline the hypothesis of the model simulation before considering the role of environmental factors, including the water environment and membrane environment. This book is a useful resource for researchers interested in investigating protein folding across molecular biology, structural biology, biochemistry, computational biology and related fields.

  • Seaweed in Health and Disease Prevention

    • 2 Edición
    • Joël Fleurence + 1 más
    • Inglés
    Seaweed in Health and Disease Prevention, Second Edition updates knowledge on the therapeutic and functional activities related to algae and their compounds. The book includes a new chapter on the use of seaweed and seaweed products in the current war against viral-based exposures, a result of the massive research effort stemming from the global Covid Pandemic, along with the improvement of the nutritional value of algae via enzymatic or fermentation treatments. These treatments are at the origin of the production of oligosaccharides, presenting interesting biological activities for the human microbiota.Chapter updates on seaweed’s biochemical characteristics such as proteins, lipids, and polysaccharides are also addressed.

  • Proteomics: A Promising Approach for Cancer Research

    Proteome Signaling Dysregulation in Cancer, Therapeutic Interventions, and Future Perspectives, Volume 2
    • 1 Edición
    • Muneeb U Rehman + 3 más
    • Inglés
    Proteomics: A Promising Approach for Cancer Research Volume 2 Proteome signaling dysregulation in cancer, therapeutic interventions, and future perspectives provides an updated overview of scientific knowledge, achievements, and findings in the field of cancer proteomics. The field of cancer proteomics is very dynamic, with emerging trends specifically related to clinical solutions. The book content was developed to help readers get up to speed on the topic and easily apply learnings into research or clinical practice.Volume 2 covers proteome signaling, their dysregulation to therapeutics options and future prospects in 17 different signaling pathways. It capitalizes the enormous interest in proteomics among academics and gives new viewpoints on this topic in cancer treatment. It is a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment.

  • Decoding Plant–Environment–Microbiome Interactions in Stress-Resilient Agriculture

    • 1 Edición
    • Asfa Rizvi + 4 más
    • Inglés
    Decoding Plant–Environment–Mi... Interactions in Stress-Resilient Agriculture delivers both foundational understanding and forward-looking perspectives on the rapidly advancing field of phytomicrobiome research. Showcasing the unique advantages of microbial partnerships in stressed soils, the book explores how optimizing plant–microbiome interactions can transform crop productivity and sustainability.Focus... on the phytomicrobiome’s diverse components—including root-associated microbiota, plant growth-promoting rhizobacteria, endophytes, phosphate-solubilizi... microorganisms, arbuscular mycorrhizal fungi, and actinomycetes—the volume reveals how these microbial networks enhance plant stress tolerance, rehabilitate degraded or contaminated soils, and sustain yields under adverse conditions.Harnessin... these natural bioresources effectively requires an integrated understanding of the complex crosstalk between plants and their associated microbes, from molecular signaling to ecological mechanisms. Drawing on insights from internationally recognized scientists and leading academicians, this book consolidates cutting-edge research and emerging innovations, providing readers with the knowledge needed to advance stress-resilient and environmentally sustainable agriculture.

  • Evolution of Nervous Systems

    • 3 Edición
    • Jon H. Kaas + 1 más
    • Inglés
    Evolution of Nervous Systems, Third edition Four-volume set includes wholly new content, all chapters from the previous edition have been thoroughly updated, and the addition of brand new contributions by leading experts. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates and the human nervous system. The basic principles of brain evolution are discussed, as well as mechanisms of change, which involve gene expression and altered courses of embryonic development. The reader can select from chapters on highly specific topics as well as those providing an overview of current thinking and approaches. This timely new edition of Evolution of Nervous Systems is a unique major reference work, offering the gold standard for those interested in evolution and in nervous systems.

  • How Sex and Gender Impact Clinical Practice

    An Evidence-Based Guide to Patient Care
    • 2 Edición
    • Marjorie R. Jenkins + 1 más
    • Inglés
    How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, is an essential resource for primary care clinicians seeking to integrate sex and gender differences into their practice. This edition emphasizes the unique framework that assists practitioners in providing personalized care. It aligns sex and gender medicine with precision medicine, helping healthcare providers attract patients who value clinicians that understand the nuances of sex and gender in healthcare.How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, includes updates on the evidence-based information on disease prevalence, diagnosis, testing, and treatment, as well as a new chapter on the sex and gender aspects of pain. Each chapter reflects how sex and gender impact disease presentation, physical examination, testing, treatment, and clinical decision-making.

  • Climate Change, Public Health, and Regional Security in the Indo-Pacific

    From Mitigation to Adaptation
    • 1 Edición
    • Sebastian Kevany
    • Inglés
    Climate Change, Public Health, and Regional Security in the Indo-Pacific: From Mitigation to Adaptation addresses the absence of solutions to looming and inevitable regional security, health, and environmental threats. To date, there has not been a comprehensive solution-based focus on climate change in the region that includes subjects such as acceptance of the consequences; implications for humanitarian assistance and disaster relief; the role of defense forces in managing migration, climate refugees, infectious diseases, and related issues such as flooding or land use change; and a further focus on climate change and implications for public health in the Indo-Pacific. This book addresses these issues and provides strategies for those living and working in the region. Written by regional experts for public health, security, and climate change practitioners, researchers and experts, as well as regional and international policymakers and opinion leaders in the area.

  • Underutilized Tuber Crops of the Himalayan Region

    Nutraceutical Potential, Processing, and Applications
    • 1 Edición
    • Arun Kumar Gupta + 1 más
    • Inglés
    Underutilized Tuber Crops of the Himalayan Region: Nutraceutical Potential, Processing, and Applications explores significant, yet underutilized, edible tubers known for their bioactive and pharmacological properties, as well as their preservation potential. The book presents detailed information on historical uses, phytochemistry, pharmacology, distribution, processing, toxicity, conservation, and future prospects of these tubers, along with their market relevance. It also covers various processing and preservation techniques to maximize their utility as ingredients or additives in food products.By integrating neglected and underutilized tubers into the current agricultural portfolio, alongside environmentally sustainable farming practices, the book provides valuable insights for food scientists and agricultural professionals working to ensure a secure, nutritious food supply while addressing the challenges of environmental change.

  • Primary Aldosteronism: Physiopathology and Diagnosis

    • 1 Edición
    • Volumen 130
    • Inglés
    Primary Aldosteronism: Physiopathology and Diagnosis, Volume 130 focuses on the physiopathology and diagnosis of primary aldosteronism, covering some important topics such as Aldosterone: synthesis and regulation, Pathophysiology of primary aldosteronism, Prevalence of primary aldosteronism and screening indications, Clinical manifestations of primary aldosteronism and cardiometabolic risk, Diagnosis of primary aldosteronism: renin activity, renin concentration and aldosterone/renin ratio, Diagnosis of primary aldosteronism confirmatory test, Diagnosis of Primary Aldosteronism: Novel Workup Strategies and Biochemical Tools, and much more. Additional sections cover Genetics in primary aldosteronism, Low-renin hypertension, Adrenal venous sampling interpretation and other diagnostic lateralization tools in PA, and Aldosterona & Cortisol cosecretion.

  • Quantum Computing in Medicine

    Transforming Drug Discovery, Protein Folding, and Genomics Research through Artificial Intelligence Integration
    • 1 Edición
    • Don Roosan
    • Inglés
    Quantum Computing in Medicine: Transforming Drug Discovery, Protein Folding, and Genomics Research through Artificial Intelligence Integration offers an insightful examination of the groundbreaking role of quantum computing in revolutionizing aspects of the medical industry. This book focuses on the profound impact that quantum computational capabilities are poised to have on drug discovery, protein folding, and, notably, genomics research. It outlines the fundamental principles of quantum computing and its complementary relationship with artificial intelligence (AI), highlighting their combined potential to solve intricate biological problems with unparalleled speed compared to traditional computational methods. Special emphasis is placed on the advancements and research efforts in leveraging quantum algorithms for the analysis of genetic data, the acceleration of genomic sequencing processes, and the enhancement of personalised medicine strategies. By providing a thorough exploration of practical applications and the current state of quantum computing in genomics, the book navigates through the challenges and ethical implications of integrating these forward-thinking technologies into healthcare systems. Aimed at professionals, scholars, and enthusiasts within the realms of medicine, computer science, and quantum physics, "Quantum Computing in Medicine" offers a forward-looking perspective on the future of genomics research and healthcare, illuminated by the innovative light of quantum computing and AI.

  • Translational Plastic Surgery

    • 1 Edición
    • Adam E.M. Eltorai + 4 más
    • Inglés
    Translational Plastic Surgery provides a comprehensive overview reflecting the depth and breadth of the field of translational research focused on plastic surgery, with input from a distinguished team of basic and clinical investigators. The practical, straightforward approach helps the aspiring investigator navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in translational plastic surgery research, allowing the reader to learn how to evaluate the quality of such studies with respect to measuring outcomes and to make effective use of all.

  • Agricultural Water Management in Africa

    Lessons Learned and Future Directions
    • 1 Edición
    • Tafadzwanashe Mabhaudhi + 2 más
    • Inglés
    Agricultural Water Management in Africa presents a comprehensive look at the current state of irrigation development and agricultural water management (AWM) practices across Africa and the Global South. Going beyond just assessment, the book offers actionable guidelines, forward-looking scenarios, and strategic investment plans to help prioritize and implement irrigation and AWM initiatives in the face of climate change.At the heart of Africa’s push for agricultural transformation is the African Union’s (AU) Framework for Irrigation Development and Agricultural Water Management. This framework lays out four key development pathways to drive impactful change in water management across the continent: (i) enhanced water control and watershed management in rain-fed agriculture; (ii) farmer-led irrigation development that empowers local growers; (iii) modernization and expansion of irrigation schemes; (iv) utilization of unconventional water sources for sustainable irrigation.The book maps out the progress and potential of these pathways on a continental scale, showcasing how the AU-IDAWM framework can shape Africa’s water-secure agricultural future. To enrich this perspective, it also draws on case studies from Asia and Latin America, creating space for meaningful South–South knowledge exchange. It thoughtfully examines cross-cutting themes such as the water–energy–food nexus and the circular economy, placing AWM in the broader context of sustainability and climate resilience.Whether you are a policymaker, researcher, practitioner, or development partner, this volume delivers critical insights into how smarter water management can drive agricultural growth, food security, and environmental stewardship in Africa and beyond.

  • 3D Printing of Food Products for Sustainability

    Innovation, Design and Applications
    • 1 Edición
    • Chaudhery Mustansar Hussain + 1 más
    • Inglés
    3D Printing of Food Products for Sustainability: Innovation, Design and Applications provides a comprehensive overview of the latest developments in 3D printing technology as applied to food production, with a focus on sustainability. Divided in 5 parts, the book blends theoretical insights with practical guidelines and real-world case studies to equip readers with a deep understanding of sustainable additive manufacturing processes in the food industry. It addresses the urgent need for innovative approaches to food manufacturing that prioritize environmental stewardship, resource efficiency, and sustainability. The book also offers a detailed exploration of the intersections between 3D printing technology and sustainable food production, making it an indispensable guide for those committed to shaping the future of food sustainability.

  • Cutting-edge Computational Intelligence in Healthcare with Convolution and Kronecker Convolution-based Approaches

    • 1 Edición
    • Allam Jaya Prakash + 2 más
    • Inglés
    Cutting-edge Computational Intelligence in Healthcare with Convolution and Kronecker Convolution-based Approaches focuses on the use of deep learning techniques in the field of medical imagine analysis. These advances offer promising progress in healthcare through improvements in diagnostic accuracy, efficiency in medical image interpretation, and breakthroughs in treatment planning. Divided into five sections, the book begins with foundational coverage of deep learning in medical imaging and fundamentals of Convolutional Neural Networks. Discover the role convolutions play in extracting meaningful features from images, aiding tasks such as diagnosis and segmentation. The second section takes a deep dive into Kronecker convolutions and their unique advantages, such as enhanced spatial hierarchy understanding, efficient parameter utilization, and improved adaptability to specific characteristics of medical images. Section three reviews specific applications in tumor detection, enhancing organ segmentation as well as disease classification, and section four explores real-world implementation of AI-driven diagnostic imaging, precision medicine via imaging analytics, and wearable devices and continuous health monitoring. The final section offers discussion on the unique challenges, trends, and potential future directions these innovative computational approaches have on medical image processing and advanced healthcare. In summary, this book takes an interdisciplinary approach to bridge the gap between theory and practice, fusing knowledge from the domains of medicine, computer science, and machine learning to address issues in healthcare through sophisticated image analysis techniques.

  • Processing, Nutrition and Value Addition Principles of Neglected and Underutilized African Foods

    • 1 Edición
    • Tilahun Seyoum Workneh + 2 más
    • Inglés
    Africa’s agroclimatic conditions are conducive to a diverse array of indigenous foods, from vegetables, fruits, and spices to fungi, insects, and roots. However, scientific documentation of traditional preservation, processing and value addition of these species and their potential to heal and nourish, is not well known to the global population. Processing, Nutrition and Value Addition Principles of Underutilized African Foods introduces traditional methods of processing and preserving indigenous foods from Africa while reporting on the commercial potential, and nutritional constituents that contribute to a more healthful society and a sustainable planet. Written by a collaboration of authors from different parts of Africa and around the world, Processing, Nutrition and Value Addition Principles of Underutilized African Foods explores the neglected and underutilized agricultural and botanical diversity of Africa. Authors show how certain species such as African nightshades, sourplum, monkey oranges, ancient grains, edible insects and more, can have health, nutrition and functional benefits while contributing to a sustainable global food system and potentially helping combat food insecurity. The taxonomy of each neglected species will be discussed along with distribution, planting area, yield and loss, and waste. The book also provides a comprehensive view of the societal attitudes towards these foods and delves into the reasons behind their neglect and underutilization, despite their inherent health benefits.

  • Clinical Research in Private Practice

    • 1 Edición
    • Jason E. Pope + 3 más
    • Inglés
    Clinical research is the tip of the spear for innovation and central in the development of improving safety and efficacy for patient centric care. Unfortunately, clinical research in academic practices is bogged down by inefficiency and infrequent regulatory oversight, thus leaving physicians unable to meet the clinical and research needs for driving innovation. Private practice is a valid practice cohort that can effectively, reliably, and reproducibly perform study related activities, for both FDA and non-FDA regulated studies, both industry-sponsored or investigator-initiat... Research in Private Practice fills a gap and provides a playbook for how to incorporate clinical research in a validated, safe, and compliant manner, allowing a needed meaningful contribution to the medical space, while concurrently maintaining fiduciary responsibility. Written for physicians by physicians.

  • Genetic Regulation of Immune Response Pathways

    • 1 Edición
    • Volumen 115
    • Inglés
    Genetic Regulation of Immune Response Pathways, Volume 115 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Chapters explore the genetic regulation of immune cells upon activation, IFN response regulation during viral infections, and the role of noncoding RNAs—including lncRNAs and ncRNAs—in immune regulation and inflammation. Additional sections examine the JAK-STAT signaling pathway in inflammatory and autoimmune diseases as a potential therapeutic target, long noncoding RNAs as key regulators of autoimmunity, and the importance of appropriate cytokine expression in maintaining immune response homeostasis.Together... these contributions provide valuable insights into the molecular and genetic mechanisms underlying immune-mediated processes.

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