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Elsevier

Libros en Ciencias de la Vida

  • Pharmacology, Physiology, and Practice in Obstetric Anesthesia

    • 1 Edición
    • Alan D. Kaye + 1 más
    • Inglés
    Pharmacology, Physiology, and Practice in Obstetric Anesthesia provides all the essentials of obstetric anesthesia in a straightforward, user-friendly format that avoids encyclopedic language and lengthy discussions, and is inclusive of other healthcare specialties and subspecialties including obstetrics, neonatal care, and more. Coverage spans the essentials of obstetrics as well as overlooked issues including obstetric pharmacology and physiology safe practice strategies, clinical concepts for vaginal delivery and C-section, high-risk pregnancy states and management of the complicated parturient, complications and medicolegal, fetus and newborn considerations, and guidelines, standards and statements related to obstetric anesthesia.Pharmacol... Physiology, and Practice in Obstetric Anesthesia is the perfect reference for an interdisciplinary group of health professionals, policymakers, and researchers working and training in the field of obstetric anesthesiology

  • Explainable AI in Healthcare Imaging for Medical Diagnoses

    Digital Revolution of Artificial Intelligence
    • 1 Edición
    • Tanzila Saba + 2 más
    • Inglés
    In an era where Artificial Intelligence (AI) is revolutionizing healthcare, Explainable AI in Healthcare Imaging for Precision Medicine addresses the critical need for transparency, trust, and accountability in AI-driven medical technologies. As AI becomes an integral part of clinical decision-making, especially in imaging and precision medicine, the question of how AI reaches its conclusions grows increasingly significant. This book explores how Explainable AI (XAI) is transforming healthcare by making AI systems more interpretable, reliable, and transparent, empowering clinicians and enhancing patient outcomes.Through a comprehensive examination of the latest research, real-world case studies, and expert insights, this book delves into the application of XAI in medical imaging, disease diagnosis, treatment planning, and personalized care. It discusses the technical methodologies behind XAI, the challenges and opportunities of its integration into healthcare, and the ethical and regulatory considerations that will shape the future of AI-assisted medical decisions.Key areas of focus include the role of XAI in improving diagnostic accuracy in fields such as radiology, pathology, and genomics and its potential to enhance collaboration between AI systems, healthcare professionals, and patients. The book also highlights practical applications of XAI in personalized medicine, showing how explainable models help tailor treatments to individual patients, and discusses how XAI can contribute to reducing bias and improving fairness in medical decision-making.Writ... by leading experts in AI, healthcare, and precision medicine, Explain[S3G1] able AI in Healthcare Imaging for Precision Medicine is an essential resource for researchers, clinicians, students, and policymakers. Whether you are looking to stay at the forefront of AI innovations in healthcare or seeking to understand how explainability can build trust in AI systems, this book provides the insights and knowledge needed to navigate the evolving landscape of AI in medicine. It invites readers to explore how XAI can revolutionize healthcare and precision medicine, shaping a future where AI is both powerful and trustworthy.

  • Preclinical Landscape in Cancer Research

    • 1 Edición
    • Ranjita Shegokar + 1 más
    • Inglés
    Preclinical Cancer Landscape discusses the issues in preclinical-to-clini... translatability of molecularly targeted cancer therapies and the need to better align tumour biology in patients With a strong focus on the status, challenges, prospects and the need of robustness of preclinical cancer research, the book acknowledges that the bar for reproducibility in performing and presenting preclinical studies must be raised to facilitate a transparent discovery process that frequently and consistently leads to significant patient benefit. In 22 chapters this book describes the current status of preclinical research in multiple cancers. This book is a timely and valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field. " Preclinical landscape in cancer research " is written by experts in the field and informed with facts directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.

  • CRISPR for Climate-Smart and Sustainable Agriculture

    • 1 Edición
    • Jen-Tsung Chen
    • Inglés
    CRISPR for Climate-Smart and Sustainable Agriculture summarizes the current genome editing technology being used in food and energy crops. It presents methods and applications of CRISPR tools for breeding climate-smart and stress-tolerant crops that are better able to resist biotic and abiotic stressors due to climate change.Gene editing tools are increasingly seen as options for improving plant health and productivity. CRISPR is one such emerging and quickly advancing crucial technology for the research field of plant physiology, plant molecular biology, and crop breeding. CRISPR for Climate-Smart and Sustainable Agriculture focuses on genetic engineering using CRISPR technology for precision breeding of crops to achieve climate resilience, stress tolerance, and higher yield. Organized by specific plant challenges, this book presents expert insights from around the globe, providing updated knowledge of CRISPR with an emphasis on facing climate change and supporting sustainable agriculture.This volume in the Genome Modified Plants and Microbes in Food and Agriculture series will be valuable for researchers, academics, and advanced-level students seeking to understand and advance the use of CRISPR technologies toward the UN Sustainable Development Goals and the Paris Climate Agreement.

  • Electrospinning and Electrospraying Encapsulation of Food Bioactive Compounds

    • 1 Edición
    • Hadis Rostamabadi + 2 más
    • Inglés
    Electrospinning and Electrospraying Encapsulation of Food Bioactive Compounds provides comprehensive approaches utilized to fabricate structured polymer fibers and particles for designing bioactive delivery systems through electrospinning and electrospraying. Divided into four parts, the chapters review practical applications, scale-up/industriali... challenges and new opportunities.This book examines electrospinning and electrospraying encapsulation, characterization approaches of bioactive-loaded electrospun fibers/electrosprayi... particles, and application of bioactive-loaded electrospun fibers/electrospraye... particles. Edited by experts in the field, this book will be of great interest to researchers, practitioners, and those who work in the various fields of encapsulation, nutraceutical, pharmaceutical, and food ingredients.

  • Aquatic Biomes

    Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity
    • 1 Edición
    • Germano Leão Demolin-Leite
    • Inglés
    Aquatic Biomes: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity explores the effects of anthropogenic activities on Earth’s aquatic biomes, species, and climate. It summarizes operational and potential monitoring tools to conserve or recover aquatic biomes at global scale. Written by international experts in ecology and biodiversity conservation, this book identifies the challenges and threats to aquatic organisms and connects them to real cases of conservation.Aquatic Biomes: Global Biome Conservation and Global Warming Impacts on Ecology and Biodiversity is an important resource for students, professors, researchers, governmental and non-governmental organizations active in biodiversity conservation and climate change mitigation seeking guidance on the best practices for aquatic biome conservation.

  • Metabolites as Signals in Immunity and Inflammation

    • 1 Edición
    • Zbigniew Zasłona + 2 más
    • Inglés
    Metabolites as Signals in Immunity and Inflammation describes the revolution in the definition of the word metabolism, highlighting changes in thinking about the whole field of immunology. These changes occur thanks to breakthrough experiments in basic research, and with the help of new technologies that allow for the testing of immunology hypotheses. In recent years, a substantial number of findings have been made around immunometabolism. What is emerging is a complex interplay between metabolic reprogramming and immunity, which is providing an extra dimension to our understanding of the immune system in health and disease.

  • Neuroglia in Neurologic and Psychiatric Disorders, Part II

    • 1 Edición
    • Volumen 210
    • Inglés
    Neuroglia in Neurologic and Psychiatric Disorders, Part II discusses glia relative to neurologic and psychiatric disorders, emphasizing cross-disease-glial cell dysfunctions. Driven by advances in genetics, transcriptomics, electrophysiologic and imaging techniques, as well as by the increase in knowledge on neuropathologic features and underlying disease mechanisms, this book bridges the gap between neuroglia basic science and neuroglia clinical research.

  • Advancing Healthcare through Decision Intelligence

    Machine Learning, Robotics, and Analytics in Biomedical Informatics
    • 1 Edición
    • Somen Dey + 4 más
    • Inglés
    Advancing Healthcare through Decision Intelligence: Machine Learning, Robotics, and Analytics in Biomedical Informatics demonstrates real-world applications of decision intelligence - specifically machine learning, robotics, and analytics - to drive innovation and improvements in healthcare delivery and outcomes. The book provides a comprehensive overview of the latest developments in decision intelligence technologies, and offers a practical resource that can help navigate through the complex landscape of healthcare decision-making. In 5 themes Advancing Healthcare through Decision Intelligence: Machine Learning, Robotics, and Analytics in Biomedical Informatics focuses on the use of data analytics aad management techniques in healthcare to improve decision-making and healthcare outcomes, on the use of robotics, robots and genomics to improve biomedical informatics, on the use of genomics, clinical decision support systems (CDSS), machine learning, and deep learning to improve precision medicine and personalized treatment and on the ethical implications of using artificial intelligence (AI) in healthcare, ensuring trust in the technology, and making sure that it can be explained and understood by all stakeholders. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Python for Quantum Chemistry

    A Full Stack Programming Guide
    • 1 Edición
    • Volumen 23
    • Qiming Sun
    • Inglés
    Quantum chemistry requires ever higher computational performance, with more and more sophisticated and dedicated Python scripts being required to solve challenging problems. Although resources for basic use of Python are widely (and often freely) available online and in literature, truly cohesive materials for advanced Python programming skills are lacking.Qiming Sun, a developer of the popular Python package PySCF, provides a comprehensive, end-to-end practical resource for researchers and engineers who have basic Python programming experiences chiefly in computational chemistry but want to take their use of the software forwards to the next level, the book provides an insightful exploration of Numpy, Pandas, and other data analysis tools. Readers will learn how to manage their Python computational projects in a professional way, with various tools and protocols for computational chemistry research and general scientific computing tasks exhibited and analysed from a technical perspective. Multiple programming paradigms including object-oriented, functional, meta-programming, dynamic, concurrent, and vector-oriented are illustrated in various technology scenarios allowing readers to properly use them to enhance their program projects. Readers will also learn how to use the presented optimization technologies to speed up their Python applications, even to the level as fast as a native C++ implementation. The applications of these technologies are then demonstrated using quantum chemistry Python applications.Python for Quantum Chemistry: A Full Stack Programming Guide is written primarily for graduate students, researchers and software engineers working primarily in the fields of theoretical chemistry, computational chemistry, condensed matter physics, material modelling, molecular simulations, and quantum computing.

  • Intelligent Nanobiosystems in Medicine and Healthcare, Volume 2

    Applications of Intelligent Nanobiosystems
    • 1 Edición
    • Vijay Mishra + 2 más
    • Inglés
    Intelligent Nanobiosystems in Medicine and Healthcare, Volume 2: Applications of Intelligent Nanobiosystems provides recent progress in the nanobiosystems arena, helping readers better design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancements in cutting-edge nanomedical technologies. This updated volume includes chapters by experts in the field, featuring an exploration of targeted therapy and drug delivery systems, analytical and imaging tools, theranostics, tissue engineering and regenerative medicines, dentistry tools and modern developments.This book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology industries as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, and biochemical and biomedical engineers working both in industry and academia.

  • Intelligent Nanobiosystems in Medicine and Healthcare, Volume 1

    Fundamentals, Fabrication and Commercialization
    • 1 Edición
    • Vijay Mishra + 2 más
    • Inglés
    Intelligent Nanobiosystems in Medicine and Healthcare, Volume One: Fundamentals, Fabrication and Commercialization provides an overview of recent progress in the nanobiosystems arena, helping readers design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancement in cutting-edge nanomedical technologies. It highlights established research and technology on intelligent nanobiosystems, their rapidly emerging aspects, and future research directions. Sections cover nanobiosystems, explore nano candidates and fabrication aspects, and delve into the challenges of commercialization.Th... book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, biochemical and biomedical engineers working both in academia and industry.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 114
    • Inglés
    Advances in Food and Nutrition Research, Volume 114, the latest release in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on the Nutraceutical potential of Mediterranean agri-food wastes and wild plants: green extraction and bioactive characterization, Yeast extract as a more sustainable food ingredient: Insights into flavor and bioactivity, Physical and chemical food safety hazards and associated health risks in seafood: a Mediterranean Perspective (Part I), Biochemical and microbial food safety hazards in seafood: A Mediterranean Perspective (Part II), Assessing food digestion in the elderly using in vitro gastrointestinal models, and much more.Additional chapters focus on Recent Advances in Non-Invasive Techniques for Assessing Food Quality: Applications and Innovations, Recent advances in carbohydrate phase behavior and rheology. Implications for processing and product formulation, and Recent advances in chemistry, biochemistry, and nutrition of dates palm fruit (Phoenix dactylifera L.) cultivars.

  • Agriculture Toward Net Zero Emissions

    • 1 Edición
    • Sandeep Kumar + 1 más
    • Inglés
    Agriculture Toward Net Zero Emissions explores how agriculture has historically contributed to carbon emissions and then takes the reader forward, offering insights into an integrated approach to reducing those emissions toward the COP26 goal. The dual challenge of increasing production to meet population and nutrition food demands while reducing the traditional emissions generated by production practices is significant. It requires understanding the foundation of current practices and then revising those underlying principles to reflect the resources and greater insights of today.This book provides an overview of the current state of the science, explores the development of policies and plans to improve carbon management, and provides examples of technology and agroecosystem management practices. It includes the latest updates in carbon neutral farming, carbon and energy management, and addresses the knowledge gap between input management, livestock management and agroecosystem management.Advancing agroecosystem science through a roadmap for improving capacity, Agriculture Toward Net Zero Emissions is a valuable resource for those seeking to develop and apply new agricultural best practices.

  • Early Detection of Alzheimer’s Disease

    Biological and Technological Advances
    • 1 Edición
    • Dennis Chan
    • Inglés
    Early Detection of Alzheimer’s Disease: Biological and Technological Advances aims to introduce to a wide audience the high global priority problem of detecting AD prior to dementia onset. According to the Alzheimer’s Association, 5.8 million Americans are living with Alzheimer’s and care costs will cost the nation approximately $290 billion (2019 Alzheimer’s Disease Facts and Figures). With the failure of recent AD drug trials, many hypothesize that by the time symptoms appear, it is too late to be treated. Early detection can offer benefits such as more choice of medications, ability to participate in clinical trials, more time for family and for care planning. This book outlines potential solutions to the above problem using opportunities arising from the technology revolution, advances in neuroscience, and molecular biology. Most importantly, it discusses a paradigm shift from a reactive to a proactive diagnostic approach, aiming to detect disease before occurrence of symptoms. Topics covered include the use of sensing technologies (e.g. smartphones, smartwatches, Internet of Things) to detect early disease-related changes, the application of data science (machine learning/AI) to extract otherwise invisible disease features from these datasets and the potential to personalize diagnosis based on tracking changes in individual behaviours. Advances in blood-based biomarkers, brain imaging, and the potential for early diagnosis to aid interventions (lifestyle, dietary, pharmacological) to delay future development of dementia are also discussed.

  • An Overview of FDA Regulated Products

    From Drugs and Cosmetics to Food and Tobacco
    • 2 Edición
    • Eunjoo Pacifici + 1 más
    • Inglés
    An Overview of FDA Regulated Products: From Drugs and Cosmetics to Food and Tobacco, Second Edition is fully updated to reflect recent advances in science and technology and new laws and regulations. Breakthroughs in cellular and gene therapy, immunotherapy, precision medicine, and digital health are changing the face of healthcare and regulation. The updates brought about by the 21st Century Cures Act and subsequent PDUFA Reauthorizations, as well as signing into law the “Modernization of Cosmetic Regulation Act of 2022,” which will transform FDA’s oversight of cosmetics, are fully reflected in all chapters of the book.This book provides graduate students and industry professionals with comprehensive information on approval processes with the FDA and other country regulation organizations. Regulatory science professionals working with not only drugs, but biologics, medical devices, food and additives, cosmetics, veterinary products, and tobacco will benefit from this comprehensive overview of the regulatory environment.

  • CRISPR-Cas Systems for RNA and Genome Editing

    • 1 Edición
    • Volumen 712
    • Inglés
    CRISPR-Cas Systems for RNA and Genome Editing, Volume 711 in this ongoing series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Massively parallel genomic perturbations with multi-target CRISPR interrogates Cas9 activity and DNA repair at endogenous sites, Genome oligopaint via local denaturation fluorescence in situ hybridization, Biochemical reconstitution of a type I-B CRISPR-associated transposon, Visualizing the conformational landscape of CRISPR-Cas9 through kinetics-informed structural studies, and much more.Additional sections cover Analysis of metal-dependent DNA nicking activities by Cas endonucleases, Biochemically characterizing the accessory proteins and ribonucleoprotein complexes of Type IV CRISPR systems, Prime editing in bacteria with BacPE, Preparation of high-purity CRISPR-based DNA base editor RNPs, Bacterial directed evolution of CRISPR base editors, Cloning and validating systems for high throughput molecular recording, Using CRISPR-Cas13 for viral nucleic acid detection, and more.

  • Viral Hepatitis in Asia and the Pacific

    Towards Elimination as a Public Health Threat
    • 1 Edición
    • Jing Sun + 2 más
    • Inglés
    Viral Hepatitis in Asia and the Pacific: Towards Elimination as a Public Health Threat documents the narratives, innovations, and scope of work in the Asia-Pacific region in starting, consolidating, and moving towards the elimination of viral hepatitis. The Asia-Pacific region is disproportionately affected by viral hepatitis, accounting for two-thirds of the global burden. Countries from low-, middle- and high-income economies have adopted different strategies to address combating and eliminating viral hepatitis. The successful experiences of the Asia-Pacific region are valuable for other regions, especially the middle- and low-income countries moving towards the achievement of the 2030 goal of elimination.Strategi... discussed include integrated approaches, negotiating universal access to diagnostics, and treatment options, including vaccines. Content further covers the critical barriers to achieve the 2030 targets for elimination of viral hepatitis and how to overcome them. This is the perfect reference for all hepatology researchers and elimination policy advocates who are dedicated to joining the fight for the 2030 goal of the elimination of viral hepatitis as a public health threat.

  • Encyclopedia of Bioinformatics and Computational Biology

    • 2 Edición
    • Shoba Ranganathan + 2 más
    • Inglés
    Bioinformatics and Computational Biology (BCB) combine elements of computer science, information technology, mathematics, statistics, and biotechnology, providing the methodology and in silico solutions to mine biological data and processes, for knowledge discovery.In the era of molecular diagnostics, targeted drug design, translational medicine and Big Data for personalized medicine, computational methods for data analysis are essential tools for biochemistry, biology, biotechnology, pharmacology, biomedical and computer science, as well as mathematics and statistics. New areas are emerging, and relatively isolated fields are becoming current hot research areas in BCB, such as Artificial Intelligence, Quantitative Biology, Computational Vaccinology, Epidemiology and Infection Diffusion, Synthetic Biology, and Phenomics. The role of BCB in characterizing SARS-CoV-2 variants and facing the COVID-19 pandemic is just one example of how these tools can help us better prepare for such future events.This Encyclopedia comprises three sections, covering Methods, Topics, and Applications. The methodologies and algorithms underpinning BCB are described in the Methods section; Topics covers traditional areas such as phylogeny, as well as more recent areas such as translational bioinformatics, cheminformatics and environmental informatics; Applications provides guidance for commonly asked “how to” questions.Navigating the maze of confusing jargon and the plethora of software tools is often confronting for students and researchers alike. This comprehensive and unique resource provides up-to-date theory and application content to address molecular data analysis requirements, with precise definitions of terminology and lucid explanations by field experts.

  • Protein and Peptide Therapeutics

    • 1 Edición
    • Volumen 212
    • Inglés
    Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Clinical Landscape in Cancer Research

    • 1 Edición
    • Ranjita Shegokar + 1 más
    • Inglés
    Cancer, a multifaceted disease, remains the leading cause of death worldwide. Ongoing research and technological advancements are continually improving the human understanding of newer treatment options. This book series aims to provide wide-ranging insights into the current landscape of cancer research, highlighting the recent advancements, current challenges, and future directions. Cancer varies widely in its formation, microenvironment, location in the body, associated risk factors, detection methodology, and treatment approaches. Early detection and prevention through lifestyle changes, regular screenings, and the awareness of symptoms are crucial for improving outcomes and survival rates. In this book series, the main focus is on trending topics, like new drug delivery, diagnostics, biomarkers, and preclinical and clinical developments in cancer research. Nanotechnology has emerged as a transformative approach in medicine, particularly in the areas of targeted drug delivery systems, imaging, and diagnostics to enhance the therapeutic efficacy and minimize adverse effects in cancer therapy. Advances in pharma, medical device, and diagnostic research, including the development of Trojan-horse therapies and precision treatments/assay kits, continue to enhance the effectiveness of cancer care over the past few decades. A total of five books are covered in this series: Drug Delivery Landscape in Cancer Research (Vol. 1)Biomarker Landscape in Cancer Research (Vol. 2)Diagnostic Landscape in Cancer Research (Vol. 3)Preclinical Landscape in Cancer Research (Vol. 4)Clinical Landscape in Cancer Research (Vol. 5) By integrating basic, applied, and innovative science concepts, this book series fosters a deeper understanding of the disease and paves the way for the development of more effective strategies. This book series serves as a valuable resource for students, researchers, regulators, and clinicians interested in understanding the complexities of cancer and the innovative approaches researched to combat this deadly disease. Nonetheless, continuous interdisciplinary, cross-country collaborations and cross-science innovation strategies are essential to further reduce the global cancer burden.

  • Essential Oil-Bearing Plants

    Agro-techniques, Phytochemicals, and Healthcare Applications
    • 1 Edición
    • M. Naeem + 1 más
    • Inglés
    Essential Oil Bearing Plants: Agro-techniques, Phytochemicals, and Healthcare Applications provides a unique, comprehensive view of the plants which produce these valuable products, exploring optimal plant production. Environmental factors such as genetic factors, geographical origins, cultivation locations, environmental conditions, and nutritional status influence their secondary components. Moreover, water variability, temperature, salt, and metal stresses significantly impact the growth, yield, and EO production of these plants by adjustment of anatomical, morphological, and biochemical development.This compilation increases the awareness of the essential oil plant species, their conservation, cultivation, and sustainable utilization. This deeper understanding of current science will aid in the efficient commercialization of products based on these plants, and will help identify knowledge gaps for future research.

  • Neuroglia in the Healthy Nervous System, Part I

    • 1 Edición
    • Volumen 209
    • Inglés
    Neuroglia in the Healthy Nervous System, Part I provides insights into newly emerging developments in neuroglia biology, focusing on the healthy nervous system. Driven by advances in genetics, transcriptomics, electrophysiological... and imaging techniques, this volume bridges the gap between neuroglia basic science and neuroglia clinical research. The book provides an overview of neuroglia biology, highlighting emerging technologies used to unravel the role of neuroglial cells in specific brain functions. The book also discusses strategies using neuroglia as a therapeutic target.

  • Berry Fruits

    Bioactives, Health Effects and Processing
    • 1 Edición
    • Asli Can Karaca + 1 más
    • Inglés
    Berry Fruits: Bioactives, Health Effects and Processing, Volume Eight in the Developments in Food Quality and Safety series, covers the most recent research on bioactives of berries, improvement of bioavailability and bioaccessibility of berry bioactives, processing of berries, and production of functional food ingredients obtained from berries. In eleven chapters, the book addresses, in detail, advanced technological applications in the sustainable production of berries, as well as bioactives/food ingredients obtained from berries. In addition, the book covers developments in novel processes for berries sustainable production, along with valorization of wastes and by-products of berry processing.The series is authored by a team of global experts in the fields of Food Quality and Safety, providing comprehensive knowledge to food industry personals and scientists.

  • Abiotic Stress in Underground Vegetables

    Response and Mitigation
    • 1 Edición
    • Milan Kumar Lal + 4 más
    • Inglés
    Abiotic Stress in Underground Vegetables provides comprehensive information on the morphological, physiological, and biochemical responses of various underground vegetable crops to abiotic stress and the strategies for managing these crops under these conditions.Climate changes pose major challenges to the productivity and yield of crops, particularly horticultural crops that bear their edible parts underground. Underground vegetable crops are highly nutritious, non-cereal plant species grown in various agro-ecological zones and play a significant role in feeding both people and animals around the world as well a providing industrial products. To address the range of challenges created by climate changes, it is crucial to understand the physiological, biochemical, and molecular responses of crops to abiotic stress and the potential mechanisms of resistance and mitigation.Presented in two parts, 'Stress Responses' and 'Stress Mitigation', Abiotic Stress in Underground Vegetables offers a detailed exploration of reactions of different underground vegetable crops to abiotic stress, along with effective management strategies for cultivating these crops. This book is an essential resource for researchers, students, crop growers, and all stakeholders in the field of crop sciences who are interested in improving the yield and productivity of these vital crops.

  • Multi-Omics Technology in Human Health and Diseases

    Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omics
    • 1 Edición
    • Muzafar A Macha + 2 más
    • Inglés
    Multi-Omics Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omic offers an advanced exploration into the comprehensive understanding of disease etiology and prognosis through multiomics approaches. This authoritative volume delves into the applications of multiomics technology in elucidating complex human health conditions and diseases. It introduces the technology's potential for biomarker identification, drug discovery, and disease prognostication. For a thorough understanding of human health and diseases, particularly cancer, it is essential to integrate knowledge of molecular biomarkers across multiple omics levels, including the genome, epigenome, transcriptome, proteome, and metabolome. This resource addresses the current gaps in knowledge among students and researchers, providing in-depth coverage of multiomics technology and its implementation in scientific research and discovery.Multi-Omic... Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omics is a pioneering resource that presents cutting-edge information on contemporary multiomics technologies for big data interpretation and their applications in deciphering complex human pathobiology. This comprehensive guide is indispensable for researchers, academics, students, and industry professionals alike.

  • Handbook of Food Allergen Detection and Control

    • 2 Edición
    • Simon Flanagan
    • Inglés
    Handbook of Food Allergen Detection and Control, Second Edition continues to be an essential resource of scientific and technical information in the food and analytical communities. This book provides information on current and emerging technologies for detecting and reducing allergens to improve allergen control overall. Written by experts in the field, it offers a wide scientific perspective on allergens and includes hot topics such as food allergen labeling and consumer perspectives on food allergen labels. Chapters are fully revised to include the latest information in the industry, including practical applications of new methods and control strategies. The book is useful for anyone in the food supply chain.The book reviews current and emerging technologies for detecting and reducing allergens, as well as issues such as traceability, regulation, and consumer attitudes. Following an introductory chapter by a distinguished expert, Part One covers allergen management throughout the food chain. Part Two details current and emerging methods of allergen detection in food, with Part Three covering methods for reducing and eliminating allergens in food. Finally, Part Four focuses on the control and detection of individual food allergens and the risks each one presents in food manufacturing.

  • Protein Misfolding in Neurodegenerative Diseases

    • 1 Edición
    • Neha Gogia + 2 más
    • Inglés
    Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

  • Energy Drinks

    Composition, Consumption, and Cautions
    • 1 Edición
    • John Higgins + 1 más
    • Inglés
    After reports of adverse events associated with energy drink consumption, including trouble sleeping, anxiety, cardiovascular events, seizures, and even death, concerns have been raised about their safety and efficacy. Energy Drinks: Composition, Consumption, and Cautions will focus on these popular beverages, their composition, ingredients, consumption patterns, performance-enhancin... effects, and their potential negative side effects and health risks. This book will go on to make recommendations that call for education, regulatory actions, changes in marketing, and additional research.The research about energy drink safety and efficacy is often contradictory, and much of the available literature is industry sponsored. This book will offer a single, unbiased, up-to-date resource for researchers, healthcare providers, and industry regulators to understand the full scope of energy drinks and their associated health risks.

  • Glucose Transporters

    • 1 Edición
    • Volumen 128
    • Inglés
    Glucose Transporters, Volume 128 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Glucose transporters and their energy homeostasis function in various organs, Molecular basis for inhibiting glucose transporters by exofacial inhibitors, Self-assembly of the insulin-responsive vesicles creates a signaling platform for the insulin action on glucose uptake, The role of lipid soluble vitamins on glucose transporter, Transport of dehydroascorbic acid by glucose transporters GLUTs, Glut-1 Inhibition in Breast Cancer Cells, Small-molecule inhibitors of glucose transporters, and more.

  • Federated Learning for Medical Imaging

    Principles, Algorithms, and Applications
    • 1 Edición
    • Xiaoxiao Li + 2 más
    • Inglés
    Federated Learning for Medical Imaging: Principles, Algorithms, and Applications gives a deep understanding of the technology of federated learning (FL), the architecture of a federated system, and the algorithms for FL. It shows how FL allows multiple medical institutes to collaboratively train and use a precise machine learning (ML) model without sharing private medical data via practical implantation guidance. The book includes real-world case studies and applications of FL, demonstrating how this technology can be used to solve complex problems in medical imaging. The book also provides an understanding of the challenges and limitations of FL for medical imaging, including issues related to data and device heterogeneity, privacy concerns, synchronization and communication, etc.This book is a complete resource for computer scientists and engineers, as well as clinicians and medical care policy makers, wanting to learn about the application of federated learning to medical imaging.

  • Human- Centric Integration of Next-Generation Data Science and Blockchain Technology

    Advancing Society 5.0 Paradigms
    • 1 Edición
    • Amit Kumar Tyagi + 1 más
    • Inglés
    Human- Centric Integration of Next Generation Data Science and Blockchain Technology: Advancing Society 5.0 Paradigms focuses on the current technological landscape, addressing the evolving integration of data science and blockchain within the context of Society 5.0. This comprehensive resource explains the convergences between data science, blockchain, and the human-centric vision of Society 5.0, while also filling the gap in understanding and navigating this transformative intersection with recent shifts towards more decentralized and data-driven paradigms.The book introduces the concept of Society 5.0, examining the historical context, and outlines the evolving technological landscape shaping our interconnected future. It discusses the fundamental principles of data science, from data collection and preprocessing to exploratory data analysis and explains the transformative impact of data science and blockchain across industries such as healthcare, finance, education, and transportation. This book is essential to understanding and shaping the future of technology and society from decentralized solutions to predictive analytics/ emerging technologies.

  • Differentiating Factors in Alzheimer’s Disease

    Gender, Ethnicity, Clinical and Treatment
    • 1 Edición
    • Henry M. Zeidan + 1 más
    • Inglés
    Differentiating Factors in Alzheimer’s Disease: Gender, Ethnicity, Clinical and Treatment addresses the question why women differ from men in terms of their risk factors and how Alzheimer's disease can be prevented at the molecular level. This book reviews the epidemiology of Alzheimer's disease describing the differences in men's and women's brain anatomy and biochemistry that may account for why women are more likely to develop Alzheimer's disease. The authors offer actions that could help to prevent or slow the progression of Alzheimer's disease in addition to discussing the most recent pharmacological treatments.

  • Wheat Wild Relatives

    Developing Abiotic Stress Tolerance under Climate Change
    • 1 Edición
    • Mohd. Kamran Khan + 3 más
    • Inglés
    Wheat Wild Relatives: Developing Abiotic Stress Tolerance under Climate Change presents a state-of-the-art outline of the problem, including issues, opportunities, and modern developments in the utilization of Wild Wheat Relatives (WWR) and related neglected species for wheat crop improvement, specifically focusing on environmental constraints. The book comprehensively discusses different wheat wild relatives, including major genus Triticum and Aegilops and their utilization in mitigating different environmental constraints using agronomic, physiological, and molecular approaches. Chapters provide insights into the advancement in the deployment of wheat genetic resources, including wild relatives and neglected species for crop improvement towards environmental issues.Wheat is a major staple food crop that has largely been focused for fulfilling the food requirements of world population during the Green revolution. Since then, it has come to cover more agricultural land than any other commercial crop. Continuously changing climatic conditions have drastically affected wheat production, with yields largely limited by environmental constraints. Theses production losses caused by crop vulnerability to climate change may be resolved by using wheat wild relatives that are closely related to cultivated genotypes and known for their beneficial traits.

  • Lipid-Drug Conjugates

    Innovation and Applications
    • 1 Edición
    • Malay K. Das
    • Inglés
    Lipid-Drug Conjugates: Innovation and Applications highlights the most recent advances and clinical applications of nano lipid-drug conjugates for enhanced drug delivery and targeting in the treatment of cancer, glioblastoma, Alzheimer’s, AIDS, and bacterial diseases. In addition, various conjugation methods to prepare lipid-drug conjugates and their pharmacokinetics in vivo are explored, together with the production and characterization of various delivery carriers for lipid-drug conjugates. The contents of this book provide pharmaceutical science researchers with the tools to explore targeted drug delivery leveraging the unique characteristics of lipid conjugates. Scientists in the corporate setting can benefit of the cases and techniques presented in developing new formulations and products.

  • A Comprehensive Guide to Rodent Models of Liver Diseases

    • 1 Edición
    • Savneet Kaur + 1 más
    • Inglés
    A Comprehensive Guide to Rodent Models of Liver Diseases provides the why, what, and how of preclinical models of liver disease. These models have not only substantially improved understanding of human liver disease pathogenesis, but also helped in developing and testing newer therapeutics as well as addressed some of the unanswered medical challenges and problems of today.This important reference gives a detailed and in-depth review of the various animal models of human liver disorders. Well-reported animal models several human liver diseases such as fatty liver disease (non-alcoholic and alcoholic) to steatohepatitis, cholestasis, fibrosis, cirrhosis and its complications are described. Preclinical models used for studying liver regeneration and liver failure are also discussed. For each model, the characteristic features, brief protocols, relevance, and limitations are provided.Preclinical models used for studying liver regeneration and liver failure are also discussed. For each model, the characteristic features, updated protocols, relevance, and limitations are provided for consideration. Finally, it provides an overview of the recently developed organoid models of liver pathology.

  • Fundamentos de la nutrición en medicina y en la atención sanitaria

    Una guía práctica
    • 1 Edición
    • Sumantra Ray + 1 más
    • Español
    Manual de referencia rápida sobre la teoría nutricional en la atención sanitaria Una buena nutrición es esencial para la salud y el tratamiento de la enfermedad. El objetivo de este nuevo manual es proporcionar a estudiantes, médicos y profesionales sanitarios información esencial para aplicar la teoría de la nutrición médica en su práctica diaria. Fundamentos de la nutrición en medicina y en la atención sanitaria plantea un enfoque sistémico de la nutrición médica. El manual trata la fisiopatología de la enfermedad en relación con la nutrición, la aplicación clínica de la teoría de la nutrición en el abordaje de la enfermedad y el papel de la nutrición en el campo de la salud pública. Su contenido abarca los fundamentos de la fisiología y la bioquímica, y analiza las interacciones fármaco-nutriente más relevantes. Se trata de un recurso de inestimable valor para quienes estén empezando a formarse en los ámbitos de la nutrición clínica y la salud pública, y deseen saber más sobre la nutrición y su función en el abordaje y la prevención de la enfermedad.

  • Clinical Applications of Echo Doppler Haemodynamics

    • 1 Edición
    • Edgar Argulian + 1 más
    • Inglés
    Clinical Applications of Echo Doppler Haemodynamics is precisely the book cardiologists and cardiology trainees have been waiting for. While this essential area of echocardiography is crucial to cardiologists and all cardiac imagers, there are no dedicated books for case-based Doppler Echocardiography. This often-overlooked discipline integrates physiology with interpretation of a wide variety of real-life echo Doppler tracings. It contains critical information for professionals around the world, including contents highly relevant to their day-to-day practice as well as its unique case studies. An abundance of knowledge in this area can currently be found randomly in various textbooks, but they lack cohesive, dedicated explanations and discussions. Clinical Applications of Echo Doppler Haemodynamics presents the reader with 100 different Doppler images, exemplifying (among other things) cardiophysiology image analysis, LVOT, pulmonary pressures, shunts, congenital heart disease and ECMO. It quite literally gives medical professionals a new way to look at the heart, better allowing them to diagnose and treat previously under-identified ailments. It is a must-have for healthcare workers interested in the most accurate, up-to-date methods of cardiac imaging and Doppler interpretation.

  • Emerging Green Processing Technologies for Beverages

    • 1 Edición
    • Roji Waghmare + 1 más
    • Inglés
    Emerging Green Processing Technologies for Beverages, Volume Seven in the Developments in Food Quality and Safety series, covers the fundamentals and recent trends in the processing of different beverages, such as herbal beverages, fresh produce-based beverages, and dairy beverages. Chapters cover a broad range of beverages to enhance knowledge in quality retention and shelf life extension. Sections summarize the influence of green technologies on nutritional quality, microbial safety, and physico-chemical characteristics. Edited by Dr. José Manuel Lorenzo and authored by a team of global experts, this book provides comprehensive knowledge to food industry personnel and scientists.This is the most up-to-date resource, covering trend topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry; Nanotechnology in food production; and Intelligent packaging and sensors for food applications.

  • Cerebral Asymmetries

    • 1 Edición
    • Volumen 208
    • Inglés
    Cerebral Asymmetries, Volume 208 summarizes research on cerebral hemispheric asymmetries and their implication for consciousness cognition, language emotion, behavior movement, and neurological disease. The book discusses anatomy and networks, genetics, hormones, and evolution, although it is primarily focused on animal research as it relates back to humans.

  • The Immunology of the Domestic Ruminants

    Cattle, Sheep, and Goats
    • 1 Edición
    • Ian R. Tizard
    • Inglés
    The Immunology of Domestic Ruminants: Cattle, Sheep, and Goats provides a thorough examination of the immune systems of these animals. It explores their normal immune functions and their roles in combating infectious and parasitic diseases, chronic inflammatory conditions, and immunodeficiency disorders. The book incorporates new data from the bovine genome project and highlights significant breed differences. Both innate and adaptive immunity are systematically covered, offering insights into basic and applied aspects of bovine immunology. In addition to detailing the immunology of major bacterial, viral, and parasitic diseases in cattle, the book reviews bovine vaccines and emphasizes the importance nutrition.This essential resource caters to professionals in large animal research and practice, providing comprehensive information on the immunology of domestic cattle, sheep, and goats.

  • Natural Biopolymers for Drug Delivery

    • 1 Edición
    • Amit Kumar Nayak + 2 más
    • Inglés
    Natural Biopolymers for Drug Delivery thoroughly details the properties, benefits and challenges of using these biomaterials in drug delivery, with a strong focus on biocompatibility and reduction of unwanted interactions. An extensive range of natural biopolymers are explored, such as cellulose, chitosan, casein, gelatin, cashew gum, and many more. Biocompatibility, toxicity and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science and pharmacology, chemical engineering and clinical science.

  • Cholecystokinin

    From Gallbladder to Cognition and Beyond
    • 1 Edición
    • Christine Feinle-Bisset + 1 más
    • Inglés
    Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function.Methods used for CCK research are also discussed. A number of chapters then covers the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.

  • Methods for Monitoring Mitochondrial Functions During Pathogen Infection

    • 1 Edición
    • Volumen 194
    • Inglés
    Methods for Monitoring Mitochondrial Functions During Pathogen Infection, Volume 194 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Mitochondrial Labeling with Fluorescent Proteins for Enhanced Morphological Characterization and Visualization of Intercellular Mitochondrial Transfer, Visualizing mitochondrial electron transport chain complexes and super-complexes during infection of human macrophages with Legionella pneumophila, Quantitative assessment of mitochondrial membrane potential in macrophages in sepsis, Quantification of mitochondrial reactive oxygen species in macrophages during sepsis, and much more.Additional chapters cover Quantification of intracellular and mitochondrial ATP content in macrophages during lipopolysaccharide-i... inflammatory response, Analysis of cytosolic mtDNA release during Staphylococcus Aureus infection, Monitoring mitochondria dynamics upon infection using a tomographic approach, A screening system to determine bacterial effects on MADCAM1 expression by high endothelial venule cells, Isolation of mitochondria from Mycobacteria infected cells, Monitoring mitochondrial localization of Mycobacterial proteins, and more.

  • Challenges in Delivery of Therapeutic Genomics and Proteomics

    • 2 Edición
    • Aliasgar Shahiwala + 1 más
    • Inglés
    Challenges in Delivery of Therapeutic Genomics and Proteomics, Second Edition is a complete reference on the biological principles involved in gene and protein delivery to cells and tissues. Highlighting the various chemical, physical, and biological approaches to protein and gene delivery, the book provides guidelines for pharmaceutical researchers in academia and corporate R&D. This new edition brings updates on the delivery of therapeutic proteomics and genomics in each chapter, and newly developed chapters on the regulatory aspects of related products, CRISPR/Cas9 gene editing, and computational tools in genomics and proteomics.After an overview of the barriers to genomics and proteomics delivery, the book dives into physical, chemical, and biological methods of gene delivery. Further chapters extensively discuss the delivery of proteins and therapeutic peptides through the respiratory, oral, parenteral, transdermal, topical, uterine, and rectal pathways. This book is the ideal reference for pharmaceutical scientists dealing with gene and protein/peptide delivery. Regulators and corporate researchers can also benefit from the wide coverage of delivery methods presented.

  • The Nervous System

    • 1 Edición
    • Volumen 5
    • Mayeen Uddin Khandaker + 1 más
    • Inglés
    The series Stem Cell Innovation in Health and Disease is a timely and fascinating collection of information and new discoveries and provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. The Nervous System, Volume 5 addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the nervous system. This volume will highlight the recent development of cutting edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to treat nervous system disorders and diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

  • Innovations in Biomedical Engineering

    Trends in Scientific Advances and Applications
    • 1 Edición
    • Shubham Mahajan + 1 más
    • Inglés
    Innovations in Biomedical Engineering: Trends in Scientific Advances and Application addresses the burgeoning demand for a comprehensive resource that not only showcases the latest advancements in this dynamic field but also shows how these innovations can be effectively translated into real-world applications. In essence, the book acts as a bridge, connecting discoveries, research, and innovations in biomedical engineering to tangible, real-world applications.

  • African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance

    Part 3. Potential Pharmaceuticals to Overcome Cancers and their Chemoresistance
    • 1 Edición
    • Volumen 115
    • Inglés
    African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part 3. Potential Pharmaceuticals to Overcome Cancers and their Chemoresistance offers detailed information on the best cytotoxic phytoconstituents of African medicinal plants that could be useful for the development of efficient pharmaceuticals that could be further explored to efficiently overcome cancers and their drug resistance. The book identifies and comments on the various classes of cytotoxic African secondary metabolites. The book also clearly identifies and comments on the best cytotoxic molecules identified in African medicinal plants. The book appears an amazing tool for Scientists to have state-of-the-art of the best cytotoxic phytoconstituents from the African flora, and to boost their clinical investigations.

  • Salmonella Biofilms, Infection, and Therapeutic Management

    • 1 Edición
    • Awanish Kumar + 1 más
    • Inglés
    Salmonella Biofilms, Infection, and Therapeutic Management provides an overview of salmonella biofilms, their detection and identification, associated salmonellosis infection, prevention and treatment.The book discusses salmonella, the formation of biofilm, and biofilm associated bacterial infection. It aims to provide insight on how salmonellosis and biofilm relate to one another as well as how they relate to other diseases in the host. It also discusses the therapeutic strategy for reducing salmonella infection and current treatment options. Salmonella Biofilms, Infection, and Therapeutic Management is a useful reference for those engaged in the study of the study of salmonella biofilm, its formation, disease manifestation, and management.

  • Foodborne and Microorganisms

    Spoilage and Pathogens and their Control
    • 1 Edición
    • Volumen 113
    • Inglés
    Foodborne and Microorganisms: Spoilage and Pathogens and their Control, Volume 110 in the Advances in Food and Nutrition Research series, updates on the latest developments in this evolving science. Chapters in this new release include Understanding the potential of fresh produce as vehicles of Salmonella enterica, Modeling and Optimization of Non-thermal Technologies for Animal-origin Food Decontamination, Space food production on safety and quality: Hazard Analysis and Critical Control Points (HACCP) plan and quality control methods, Inactivation of foodborne pathogens by nonthermal Technologies, Foodborne sporeforming bacteria: challenges and opportunities for their control through food production chain, and more.Additional sections focus on Spoilage microorganisms in the dairy industry, Foodborne pathogens in the pork production chain, Food spoilage fungi: main sources and controlling strategies, Advanced data analytics and ‘omics’ techniques to control enteric foodborne pathogens, and Prevention of foodborne virus and pathogens in fresh produce and root vegetables.

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