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Elsevier

Libros en Ciencias de la Vida

  • Cytokine Response Against Major Human Viral Infections

    • 1 Edición
    • Mukesh Samant + 1 más
    • Inglés
    Cytokine Response Against Major Human Viral Infections provides in-depth coverage of the immunological response against human viral infections and the role and impact of cytokines on disease pathogenesis and host immune response.Cytokines, as a part of innate immunity, initiate the development of antiviral and TH 1-type immune responses. Cytokines also affect the adaptive immune response and disease manifestation. In five sections, this book gives a comprehensive introduction to the clinical manifestations of viral and infectious diseases; details the role of cytokines in DNA virus infections, RNA virus infections, and reverse transcribing virus infections; and gives insights into the recent advances and strategies in diagnostic tools and therapeutic and prophylactic measures.Cytokine Response Against Major Human Viral Infections is valuable resource for both researchers in immunology and virology, as well as for those in the biotech and pharmaceutical industries, engaged in the study of cytokines and their immunological response against human viral infections.

  • Genetic Disease Discovery and Therapeutics

    • 1 Edición
    • Moyra Smith
    • Inglés
    **Selected for 2026 Doody's Core Titles in Clinical Genetics**Genetic Disease Discovery and Therapeutics presents information on the methods used to determine how specific gene defects influence pathology and phenotype and to review novel therapeutic approaches designed for the treatment of specific genetic and genomic disorders.This book investigates methodologies applied to the characterization of downstream functional effects of specific gene mutations associated with altered phenotypes and clinical disease. It documents evidence of how specific mutations influence pathology and lead to disease manifestations. This book also reviews information on therapeutic approaches that could potentially be applied in diseases due to gene defects. Genetic Disease Discovery and Therapeutics is a valuable reference for scientists and graduate students involved in laboratory research related to genetics, physiology, pathology, and pharmacology as well as clinicians who encounter patients with genetic disorders.

  • Mass Transfer Operations in the Food Industry

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari + 1 más
    • Inglés
    Mass Transfer Operations in the Food Industry, a new volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for mass transfer processes, including crystallization, distillation, gas adsorption, and ionic exchange. These processes and unit operations are very important in the manufacture of products such as salt, sugar, edible oils and flavorings, essential oils, soft drinks, etc. All chapters emphasize basic texts relating to experimental, theoretical, computational, and/or applications of food engineering principles and the relevant processing equipment to mass transfer unit operations.Written by experts in the field of food engineering in a simple and dynamic way, this book targets industrial engineers working in the field of food processing and within food factories to make them more familiar with the particular food processing operations and equipment.

  • The Immune System

    Mental Health and Neurological Conditions
    • 2 Edición
    • Hymie Anisman + 2 más
    • Inglés
    The Immune System: Mental Health and Neurological Conditions fully investigates how immune-related cellular, molecular and anatomical changes impact mental functioning. This book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut, aka, the microbiome, and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. New chapters and sections on peripheral and central mechanisms in relation to viral pathogens, RNA editing to treat diseases, and COVID-19 will be included. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. This book covers both mental-health conditions and degenerative disorders of the brain, including depression, schizophrenia, autism-like spectrum disorders, Parkinson’s and Alzheimer’s-like dementia.

  • Plant-Based Proteins

    Sources, Extraction, Applications, Value-chain and Sustainability
    • 1 Edición
    • Fatih Ozogul + 2 más
    • Inglés
    Plant-based Proteins: Sources, Extraction, Applications, Value-chain and Sustainability provides the latest findings and most recent approaches and trends on clean label proteins. Divided into six sections, including Cereal-based proteins, Pseudocereal-based proteins, Protein from pulses, Protein from seeds and nuts, Protein from fruits and vegetables, and Plant-based proteins (value-chain and sustainability), the book extensively covers the composition, quality characteristics, and comparative analysis of plant- and animal-based proteins and their potential industrial applications.A comprehensive reference offering the state-of-the-art necessary insights on the recent and potential uses of plant proteins, this book is an excellent resource for academics and researchers in food science and engineering as well as industrial food engineers and technicians.

  • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

    Developmental Disorders
    • 7 Edición
    • Reed E. Pyeritz + 2 más
    • Inglés
    **Selected for 2026 Doody's Core Titles as an Essential Purchase in Clinical Genetics**For decades, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics has served as the ultimate resource for clinicians integrating genetics and genomics into medical practice. With detailed coverage in contributions from more than 250 of the world’s most trusted authorities in medical genetics and a series of 11 volumes available for individual sale, the Seventh Edition of this classic reference includes the latest information on seminal topics such as prenatal diagnosis, genome sequencing, public health genetics, genetic counseling, and management and treatment strategies to complete its coverage of this growing field for students, health providers, and researchers involved in the care of patients with genetic conditions, and increasingly, all areas of health and disease. This comprehensive yet practical resource emphasizes theory and research fundamentals related to the applications of medical genetics and genomics across the full spectrum of inherited disorders and applications to medicine more broadly.In this volume, leading physicians and researchers thoroughly examine medical genetics and genomics as applied to developmental disorders, as well as genetic conditions that affect hearing and vision. Here genetic researchers, students, and health professionals will find new and fully revised chapters on human developmental genetics, disorders affecting craniofacial development, chromosomal abnormalities, including aneuploidies and structural abnormalities, hereditary hearing impairment, and various genetic conditions of the eye.With regular advances in genomic technologies propelling precision medicine into the clinic, Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics, Seventh Edition bridges the gap between high-level molecular genetics and practical application and serves as an invaluable clinical tool for health professionals and researchers.

  • Green Analytical Methods and Miniaturized Sample Preparation techniques for Forensic Drug Analysis

    • 1 Edición
    • Rajeev Jain + 1 más
    • Inglés
    Green Analytical Methods and Miniaturized Sample Preparation techniques for Forensic Drug Analysis provides a comprehensive overview of GAMs in forensic drug analysis, including green sample preparation techniques, in-situ analytical platforms (such as DIC and µPADs), and on-site sample preparation. The book discusses not only eco-friendly GAM’s, but also methods which provide high sample throughput and cost-effective analysis, and are therefore of immense use in resource limited laboratories of developing countries. This is a comprehensive source of literature for analytical scientists in this developing area of sustainable and affordable analytical methods.

  • Pathophysiological Aspects of Proteases in Cancer

    • 1 Edición
    • Sajal Chakraborti + 2 más
    • Inglés
    Pathophysiological Aspects of Proteases in Cancer provides a comprehensive overview of the multifaceted field of proteases in the cellular environment and focuses on the recently elucidated functions of complex proteolytic systems in physiology and pathophysiology. The book both gives insights on the general aspects of the role of proteases in cancer, their role as diagnostics and prognostics biomarkers, their impact on chemoresistance, and the future cutting-edge technologies like cocktail therapies and Cyber Knife technology. Given the breadth and depth of information covered in the respective contributions, the book will be immensely useful for researchers in oncology and working to identify targets for drug development.Multidis... in scope, the book bridges the gap between fundamental and translational research, with applications in the biomedical and pharmaceutical industry, making it a thought-provoking read for basic and applied scientists engaged in biomedical research.

  • Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders

    • 1 Edición
    • Gabriele De Rubis + 5 más
    • Inglés
    Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders focuses on 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modeling. The book, written by a team of leading experts in the field, is an essential resource for anyone interested in the future of CRD treatment. Chapters discuss the emerging therapeutic approaches for CRDs, including biologicals and phytoceuticals. Core chapters of the book then cover the application of 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modeling to different CRDs. The book concludes with a discussion of the current clinical trials and future prospects for the management of CRDs.This is a valuable resource for researchers, clinicians, and other healthcare professionals who are interested in the latest technological advances in the field of CRDs. It will also be of interest to students and scientists working in the fields of pharmaceutical sciences, microfluidics, bioinformatics, drug design, drug delivery, and 3D printing.

  • Small Lungs and Obstructed Airways

    Reassessing Chronic Obstructive Pulmonary Disease
    • 1 Edición
    • Peter Burney
    • Inglés
    Small Lungs and Obstructed Airways: Reassessing Chronic Obstructive Pulmonary Disease proposes an alternative perspective to current explanations for the distribution of chronic lung disease. The book considers the link between chronic respiratory disease and associated mortality with smaller lungs rather than obstructed airways and explores other factors contributing to poor lung health besides the current emphasis on the roles of air pollution, occupational exposures, and cardio-metabolic disease. It presents the findings of the Burden of Obstructive Lung Disease (BOLD) study, sharing new views on the prevalence of obstructive lung disease and risk factors across various global regions. Sections cover decreased lung function, including the prevalent views on the impact of both household and external air pollution, occupational exposure, and the prenatal and postnatal/childhood environment in the etiology of impaired lung function and COPD. The book then moves on to discussions on the impact poverty and nutrition has on lung health, sharing the findings of the BOLD study regarding its effect on lung function and risk of COPD in lower-income countries. The book closes with a chapter outlining the clinical and public health implications of the findings discussed in the book.

  • Digital Health

    Telemedicine and Beyond
    • 1 Edición
    • Dipu Patel
    • Inglés
    Digital Health: Telemedicine and Beyond describes practical ways to use digital health tools in clinical practice. With a strong focus on case studies and patient outcomes, this title provides an overview of digital medicine, terms, concepts, and applications for the multidisciplinary clinical practitioner. Chapters provide a concise, yet comprehensive understanding of digital health, including telemedicine, mHealth, EHRs, and the benefits and challenges of each. The book gives insights on risks and benefits associated with storing and transmitting patient information via digital tools and educates clinicians in the correct questions to ask for advocacy regarding state laws, scope of practice, and medicolegal implications.It also addresses the ethical and social challenges that digital health raises, how to engage patients to improve shared decision-making models and how digital health tools can be integrated into clinical practice. This book is a valuable resource for clinicians and medical educators of all health professions, including physicians, physician associates, nurses, pharmacists, physical therapists, occupational therapists, speech therapists, students, and all those who wish to broaden their knowledge in the allied field.

  • Nanoparticles Synthesis by Soil Microbes

    Application in Plant Production and the Environment
    • 1 Edición
    • Ajay Kumar + 3 más
    • Inglés
    Nanoparticles Synthesis by Soil Microbes: Application in Plant Production and the Environment, a volume in the Plant and Soil Microbiome series, presents an advanced and recent description of plant and soil microbiome in the nanoparticle synthesis and their application in sustainable agriculture and environment. In The book covers the broad aspect of microbial synthesized nanoparticles in their synthesis and application in sustainable agriculture and environmental management in line with the recent and timely further interest in the biogenic synthesis of nanoparticles due to their environmentally-frie... cost-effective, rapid, and efficient nature.The microbial cell contains various bioactive compounds, and in the last few years, nanoparticle syntheses from the microbial cell have been increasingly sought due to their overall cost effectiveness and less toxic residual products. Microbe-assisted synthesis of nanoparticles could provide a green, environmentally benign, rapid and efficient route for the fabrication of biocompatible nanostructures with diverse physical-chemical and optoelectronic properties.

  • The multitasking molecular chaperone Hsp60

    Structure, function, and impact on health and disease
    • 1 Edición
    • Francesco Cappello + 2 más
    • Inglés
    The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease provides an overview of this key component of the Chaperone System (CS). The book covers various areas of medicine in which Hsp60 chaperonopathies have been identified. Various chapters discuss the Hsp60 structure, localization, functions, and participation in disease mechanisms both genetic and acquired, focusing on humans but also presenting data obtained from pro- and eukaryotic experimental models. The main goal is to provide information accessible to all healthcare professionals in a way that can be understood by nonspecialists and that would stimulate clinical and pathological detection of Hsp60 chaperonopathies.Mol... mechanisms are briefly described with the purpose of illuminating roads toward accurate diagnosis, treatment, and patient monitoring. Consequently, the possibility of developing/applying chaperonotherapy centered on Hsp60, as a therapeutic tool or target, is analyzed in many sections of this book, across a variety of medical specialties. Over the last several years, the importance of the CS as a physiological system has been brought to prominence and its roles in health and disease made clear. The molecular chaperones, including Hsp60, are the key components of the CS that are typically cytoprotective, but they can also be etiopathogenic factors, causing diseases named chaperonopathies.

  • Rhizomicrobiome in Sustainable Agriculture and Environment

    • 1 Edición
    • Joginder Singh Panwar + 1 más
    • Inglés
    Rhizomicrobiome in Sustainable Agriculture and Environment explores the important potential of biocontrol agents in the reduction of overexploitation of synthetic pesticides, enhancing crop production, and maintaining the natural texture and health of agricultural soils. As concerns about sustainable production challenge current practices, this book presents opportunities for utilizing biological systems as part of the solution. Written by a team of global experts, sections explore the full range of rhizomicrobiome topics, including sustainable agriculture, food security, and environmental management. This will be a valuable resource for researchers, academics, and advanced students.Rhizomicrob... is a significant part of plant biological system which impacts the plant growth and survival in different physiological conditions. Its composition includes different microbial networks whose presence is mainly impacted by the root exudates. Archaea, bacteria, protozoa, fungi, oomycetes, nematodes, microarthropods etc. are the significant parts of the rhizomicrobiome. Rhizomicrobiome could be that novel ecosystem housing the bioinoculants that can help create sustainable, productive growth environments.

  • Drug Discovery Stories

    From Bench to Bedside
    • 1 Edición
    • Bin Yu + 1 más
    • Inglés
    Drug Discovery Stories: From Bench to Bedside presents a collection of cases on the development of highly successful pharmaceuticals. It delves into the realm of drug discovery, exploring the structural biology and biological functions of the sought-after targets. The book covers the identification of promising compounds, their transformation from hits to leads through meticulous optimization, and the elucidation of how key compounds interact with the target (in essence, providing invaluable insights for drug design). Additionally, it covers essential information such as the pivotal biological and PK data of lead compounds, any noteworthy clinical results, and a comprehensive overview of other candidate compounds.The field of drug discovery and development has experienced rapid evolution, with numerous new drugs receiving approval each year. While several books have been published on this subject, there is a pressing need for a new book series that accurately reflects the current advancements in drug discovery. This book aims to not only cater to the drug discovery community but also engage other communities involved in chemical biology, synthetic chemistry, and pharmacology.

  • Sustainable Agriculture under Drought Stress

    Integrated Soil, Water and Nutrient Management
    • 1 Edición
    • Hassan Etesami + 1 más
    • Inglés
    Sustainable Agriculture under Drought Stress: Integrated Soil, Water and Nutrient Management seamlessly blends cutting-edge research with practical applications, offering a unique perspective on tackling this urgent challenge. Through a multidisciplinary lens, this book provides a cohesive and comprehensive understanding of both the current landscape and future prospects. Readers will find this book equips them with the knowledge and strategies required to manage soil nutrients and water effectively, ensuring the health of both soil and plants, especially in arid and semi-arid regions, where solutions are urgently needed.This book offers actionable insights into mitigating the impacts of climate change on agricultural systems, making it essential reading for anyone invested in sustainable land management and food security.

  • γδ T Cell Cancer Immunotherapy

    Evidence-Based Perspectives for Clinical Translation
    • 1 Edición
    • Marta Barisa
    • Inglés
    γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation sets out and critically discusses the current clinical and relevant preclinical γδ T cell immunotherapy landscape.In five chapters, field experts discuss the challenges facing γδ T cell oncoimmunotherapy, propose solutions, and map next steps.Particular attention is given to summarizing our understanding of the complex, translationally relevant human γδ T cell biology, the evidence basis for designing γδ T cell combination trials and data-driven perspectives on what is known—and what isn’t—about γδ T cell therapeutic persistence. Various perspectives are provided on how issues of cytotoxic effector function, functional exhaustion, and cytokine addiction can be mitigated using gene engineering.A chapter is dedicated to the systematic review of all γδ T cell immunotherapy trials to date, and the cell therapy products that were used in these trials. The final chapter discusses allograft persistence-enhancem... techniques in the context of γδ T cell therapy, covering lymphodepleting chemotherapy and synthetic stealth engineering.γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation gives an updated and comprehensive insight into the current state of γδT cell immunotherapy, which is of interest to existing translational γδ T cell specialists, the proliferating range of academic scientists and commercial scientists entering the field, as well as clinicians who may encounter γδ T cell immunotherapy in the clinic, or are wishing to familiarize themselves with noncanonical lymphocyte immunotherapy.

  • Marine Molecules from Algae and Cyanobacteria

    Extraction, Purification, Toxicology and Applications
    • 1 Edición
    • Paz Otero Fuertes + 1 más
    • Inglés
    The marine environment is a rich but underexploited source of commercially interesting natural products with different applications. Several marine organisms, such as seaweeds, microalgae, sponges, cyanobacteria, ascidians, and fungi, are sources of natural valuable molecules. These chemical compounds range from small molecules and enzymes to highly complex secondary metabolites that show bioactivities in physiological systems. It is thus of great importance to collect information concerning the discovery of these molecules and their characterization and relation to human diseases. Gathering data about novel technologies and sources to obtain and isolate such as precious molecules as well as new applications for them is extremely appreciated in the chemical field. It is very useful for chemists to obtain these molecules with high purity to be used as analytical standards to calibrate the chromatography equipment. Many of these compounds are not commercially available, so the isolation methods of these molecules from microalgae, seaweeds, and cyanobacteria is a challenging task. The availability of some marine molecules has been a long-term problem due to the difficulty of their synthesis. Because of the complexity of their structure, the total synthesis has been shown to be difficult. Developing protocols to obtain reference standards from natural sources has shown satisfactory results in the chemical industry. Marine Molecules From Algae and Cyanobacteria addresses these topics, highlighting fundamentals of biomolecules, their roll in living organism, structure elucidation, sources, important characteristics, and the industrial applications of these biomaterials for educational (academic) as well as industrial purposes. This book covers all methodologies used in the search of marine natural products: screening of marine molecules by chemical methods like HPLC, LC-MS/MS, the isolation of high-value compounds with biotechnological potential, discovery of new molecules, and the optimization of green extraction procedures of these molecules, such as supercritical fluid extraction and pressurized solvent extraction, and other alternative chemical techniques applied in the exploration for marine compound.

  • A New Era in Alzheimer's Research

    Pathogenesis, Prevention, and Treatment
    • 1 Edición
    • Sandeep Kumar Singh + 1 más
    • Inglés
    A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals.

  • Genome Editing for Neurodegenerative Diseases

    From Concept to Clinical Trials
    • 1 Edición
    • Sandeep Kumar Singh + 3 más
    • Inglés
    Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.

  • Immunotoxicogenomics

    A Multidisciplinary Approach in Systems Toxicology
    • 1 Edición
    • Md. Naimat Ali + 2 más
    • Inglés
    Immunotoxicogenomics... A Multidisciplinary Approach in Systems Toxicology covers the major mechanisms and effects of toxic substances on the immune system, and on the regulation of gene expression. This includes the aims, opportunities, clinical applications, recent developments, and emerging and future trends. The book begins with a discussion of the systemic approach to toxicants, but also looks at current genomic tools used to assess immunotoxicity and systems biology methods used in immuno-toxicogenomic... Other topics include genomic expression profiling, gene expression as a tool to understand and predict immunotoxicity, immunotox-icogenomic... as a screening tool, and the assessment and analysis of Immunotoxicogenomics data.This book provides a collaborative, multidisciplinary approach for researchers in the fields of toxicology, genetics, immunology, and others engaged in the study on the effects of toxic substances on immune responses.

  • Conductive Hydro Drying of Foods

    Principles and Applications
    • 1 Edición
    • C. Anandharamakrishnan + 2 más
    • Inglés
    Conductive Hydro Drying of Foods: Principles and Applications presents the current state of this emerging field, touching basics of novel drying approaches, introducing the concept of conductive hydro drying, and detailing its applications in food processing. The book explores novel drying techniques and covers the drying of various foods, including fruits and vegetables, meat, fish, poultry, and egg, spices and herbs, cereals and pulses, and other edible materials. It also brings chapters on trends and prospects, providing emphasis on the scope for low-cost drying, drying, or heat-sensitive foods. Edited by authors with interdisciplinary backgrounds and strong expertise in the field of food drying, this is a valuable resource to research and industry professionals working in allied fields.

  • Microbiology and Health Benefits of Traditional Alcoholic Beverages

    • 1 Edición
    • Jyoti Prakash Tamang
    • Inglés
    Microbiology and Health Benefits of Traditional Alcoholic Beverages is an interdisciplinary reference for students, researchers, and academics studying anthropology and food and beverage science, especially those with interest in fermentation. Fermented beverages and alcoholic drinks are culturally and socially accepted products for consumption, drinking, entertainment, as well as for customary practices and religious purposes. Due to variation in substrates, climatic conditions, geographical locations and ethnicity, a colossal diversity of microbial community as well as major domains have been reported in the different varieties of fermented beverages of the world.This book covers the cultural context of these beverages along with their biochemistry, health benefits, and therapeutic uses. Topics include winemaking, malting and brewing of wine and beer, and culturally specific beverages and practices such as fermented palm beverages and agave.

  • Deciding with Children in Pediatrics

    Children's Participation in Healthcare Decision-Making
    • 1 Edición
    • John Massie + 2 más
    • Inglés
    **2026 PROSE Award Finalist in Clinical Medicine**Deciding with Children in Pediatrics: Children’s Participation in Healthcare Decision-making provides the ethical underpinning and offers practical strategies to foster meaningful participation of children in decisions affecting their healthcare. It will assist clinicians to bring forward the perspectives and values of the child, ensuring their preferences are incorporated into decision-making or appropriately justified when this is not possible. This is to both improve healthcare delivery and serve the best interests of children— now and as decision-makers in the future.This book reviews theories underpinning the concept of deciding with children and explores how pediatric decision-making is standardly managed. It then proposes a model for making healthcare decisions with children. A panel of experienced clinicians and ethicists demonstrate, via a series of case studies, how to promote children’s participation across a variety of clinical areas, child ages, and developmental stages. It concludes with a review of questions, concerns, and challenges. Deciding with Children in Pediatrics: Children’s Participation in Healthcare Decision-making helps bridge the gap between philosophy and practical clinical ethics and creates a frame of reference for children’s healthcare providers.

  • Protocols in Biochemistry and Clinical Biochemistry

    • 2 Edición
    • Buddhi Prakash Jain + 2 más
    • Inglés
    Protocols in Biochemistry and Clinical Biochemistry, second edition, offers clear, applied instruction in fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose, and cholesterol levels, among other diagnostics. Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods, and troubleshooting, all to support a range of study types and clinical diagnostics. This fully revised edition has been expanded and enriched to feature 100 protocols, as well as chapter key term definitions and worked examples. All-new protocols added to this edition include identification of lipids by TLC, lipid per oxidation measurement by thiobarbituric acid assays, determination of serum amylase, catalase activity assay, superoxide dismutase assay, qualitative analysis of plant secondary metabolites, qualitative analysis of photochemicals, quantitative estimation of secondary metabolites, estimation of chlorophyll contents, and starch determination, among others. Each protocol is written to help researchers and clinicians easily reproduce lab methods and ensure accurate test results.

  • Artificial Intelligence in Urology

    Present and Future
    • 1 Edición
    • Andrew J Hung
    • Inglés
    Artificial Intelligence in Urology: Present and Future summarizes the cutting-edge development and adoption of Artificial Intelligence (AI) technologies in urology. The book explores barriers that prevent the further adoption of AI technologies, provides ethical considerations, and investigates the future role AI is expected to play. In addition, it includes applications of AI technology in the diagnosis and treatment of cancers (prostate, bladder, and more) and kidney stones, and in both adult and pediatric care. This is the perfect reference for researchers developing AI technologies for clinical applications and for clinicians who aim to effectively adopt AI technologies to solve clinical questions.

  • Chemical and Genomic Methods in Nucleic Acid Biology

    • 1 Edición
    • Volumen 705
    • Inglés
    Chemical and Genomic Methods in Nucleic Acid Biology, Volume 704 highlights new advances in the field of nucleic acids, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this new release include A real-time FRET-based biochemical assay for DNA deaminase enzymology and inhibition, DEER spectroscopy to probe DNA wrapping by protein complexes, PAR-dCLIP: Enhancing PhotoActivatable Ribonucleoside analog-enhanced CrossLinking and Immunoprecipitation through capture of bound 5’ terminal RNA fragments, Site-specific targeting of transgene cDNA insertion, Simultaneous Profiling of the RNA Targets of Two RNA-Binding Proteins Using TRIBE-STAMP, and much more.Additional chapters cover Ensemble FRET Approach to Directly and Continuously Monitor Protein? DNA Interactions, Utilizing nuclear extracts to characterize protein-DNA interactions at the single-molecule level, RNA-Guided Protease Activation in CRISPR-Cas, Activity-based profiling of RNA modifying enzymes, Purification of Cas9 and Cas12a for Peptide-Assisted Genome Editing, Studying the intersection of nucleoside modifications and SARS-CoV-2 RNA-dependent RNA transcription using an in vitro reconstituted system, and more.

  • Moving Towards Everlasting Artificial Intelligent Battery-Powered Implants

    • 1 Edición
    • Marvellous Moyo + 1 más
    • Inglés
    Moving Towards Everlasting Artificial Intelligent Battery-Powered Implants presents the development process of new artificial intelligent (AI) charging systems for battery-powered implants that can last for a lifetime after implantation. This book introduces new strategies to address the limitations of technologies that have been employed to improve the lifespan of medical implants. This book also provides guidelines that medical implant manufacturers can adopt during their product development stages—this adds a new dimension of research on medical device implants that can be a game changer for the AI medical implants industry. Researchers, engineers, and graduate students in the elds of biomedical engineering, electrical engineering, and computer science will find this text helpful as they seek to understand the potential of AI systems to help achieve sustainability in healthcare and make current medical implants relevant in the future.

  • Radiomics and Radiogenomics in Neuro-Oncology

    An Artificial Intelligence Paradigm – Volume 2: Genetics and Clinical Applications
    • 1 Edición
    • Sanjay Saxena + 1 más
    • Inglés
    Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm—Volume 2: Genetics and Clinical Applications provides readers with a broad and detailed framework for radiomics and radiogenomics (R-n-R) approaches with AI in neuro-oncology. It delves into the study of cancer biology and genomics, presenting methods and techniques for analyzing these elements. The book also highlights current solutions that R-n-R can offer for personalized patient treatments, as well as discusses the limitations and future prospects of AI technologies.Volume 1: Radiogenomics Flow Using Artificial Intelligence covers the genomics and molecular study of brain cancer, medical imaging modalities and their analysis in neuro-oncology, and the development of prognostic and predictive models using radiomics.Volume 2: Genetics and Clinical Applications extends the discussion to imaging signatures that correlate with molecular characteristics of brain cancer, clinical applications of R-n-R in neuro-oncology, and the use of Machine Learning and Deep Learning approaches for R-n-R in neuro-oncology.

  • Advances in Insect Physiology

    • 1 Edición
    • Volumen 67
    • Inglés
    Advances in Insect Physiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics including Insecticidal RNAi delivered as biopesticide, Cry toxins, Vip3 insecticidal proteins: Structure and Mode of Action, New plant/other bacteria toxins, Engineered insecticidal proteins, Resistance to insecticidal proteins, and Photorhabdus toxins across Gram-negative bacteria. Each chapter is written by an international board of authors.

  • Lipidología clínica

    • 3 Edición
    • Christie M. Ballantyne
    • Español
    Lipidología clínica proporciona a los clínicos una guía clara y autorizada para el tratamiento de los pacientes con niveles elevados de colesterol y otros trastornos lipídicos aterogénicos. Un recurso inestimable para cardiólogos, lipidólogos, endocrinólogos e internistas, esta obra única cubre desde la ciencia básica y la patogenia de la enfermedad aterotrombótica hasta la evaluación del riesgo y las más recientes opciones terapéuticas. Totalmente actualizada, esta tercera edición ofrece una cobertura exhaustiva y completa de la lipidología.

  • Targeting Signaling Pathways in Solid Tumors Part C

    • 1 Edición
    • Volumen 389
    • Inglés
    Targeting Signaling Pathways in Solid Tumors, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Drugging the Undruggable: Advances in Targeting KRAS Signaling in Solid Tumors, Emerging Trends in Gastrointestinal Cancers: Targeting Developmental Pathways in their Carcinogenesis and Tumor Progression, Importance of targeting various cell signaling pathways in solid cancers, Targeting signaling pathways in cancer stem cells: a potential approach for developing novel anticancer therapeutics, Factors affecting heterogeneity in breast cancer microenvironment: A narrative review, and much more.Additional sections cover Exploring TLR Signaling Pathways as Promising Targets in Cervical Cancer: The Road Less Travelled

  • Advances in Host Genetics and Microbiome in Colorectal Cancer-Related Phenotypes

    • 1 Edición
    • Volumen 112
    • Inglés
    Advances in Host Genetics and Microbiome in Colorectal Cancer-Related Phenotypes, Volume 112 in the Advances in Genetics series, highlights new advances in the field with this new volume presenting interesting chapters on topics such as What we need in colorectal cancer research, and why?, Host Genetics and Microbiota procedures in colorectal cancer research, Host Genetics-associated mechanisms in colorectal cancer, Microbiota-associate... mechanisms in colorectal cancer, Inflammation regulation in colorectal cancer, Microbiota and detrimental protein metabolites in colorectal cancer, Microbiota and other detrimental metabolites in colorectal cancer, Microbiota and beneficial metabolites in colorectal cancer, and much more.

  • COVID-19 and the Cardiovascular System

    From Pathophysiology to Clinical Management
    • 1 Edición
    • Brian C. Case + 1 más
    • Inglés
    COVID-19 and the Cardiovascular System: From Pathophysiology to Clinical Management comprehensively covers COVID-19’s impact on the cardiovascular system. Coverage includes the pathophysiology, clinical manifestations, diagnostic approach, treatment options, and clinical outcomes of patients presenting with COVID-19 with cardiac involvement. In a concise but comprehensive manner, the book's content reviews the epidemiology, risk factors, pathophysiology of COVID-19, cardiovascular clinical manifestations, non-invasive and invasive diagnostic evaluation, therapeutic options, outcomes data, role of the COVID-19 vaccine, and long-term outcomes/management.... is the perfect reference for basic and clinical researchers in cardiovascular medicine as well as practicing clinical cardiologists who are dealing with COVID-19 patients with cardiac involvement.

  • Theranostics Nanomaterials in Drug Delivery

    • 1 Edición
    • Prashant Kesharwani + 1 más
    • Inglés
    Theranostics Nanomaterials in Drug Delivery presents the most recent advances in the development of theranostic nanomaterials for drug delivery. This book compiles reports and studies on the latest changes and improvements of theranostic nanocarriers such as nanoemulsions, liposomes, exosomes, polymeric micelles, PLGA nanoparticles, chitosan nanoparticles, dendrimer, quantum dots, silica nanoparticles, gold nanoparticles, silver nanoparticles, magnetic nanoparticles, and many more, all of which can help in the sensitive diagnosis, precise targeting, and efficient and controlled delivery of nanomaterials to control various diseases at different clinical stages.Theranostics nanomaterials in drug delivery will serve as a solid foundation and reference for pharmaceutical scientists, undergraduate and postgraduate students, researchers, and experts in the medical field involved in the development of advanced drug delivery systems.

  • Diseases of Bivalves

    Historical and Current Perspectives
    • 1 Edición
    • Roxanna Smolowitz
    • Inglés
    Diseases of Bivalves: Historical and Current Perspectives is a novel reference covering all known diseases of cultured and fished bivalve mollusks from around the world. Written by a renowned expert in the field of shellfish, the author presents a historical perspective of disease discovery, explaining when and where each disease first occurred and identified to current research findings. This reference describes the infectious agent that causes each disease and environmental conditions that promote infection symptoms and signs of the disease in the host, both as noted in individual animals and in the affected populations, and resultant morbidity and mortality of infected populations. The book offers past and current possible prevention and management methods to control disease in current and projected geographical locations. This is a complete resource for aquatic and veterinary pathologists, aquaculturists, government regulators, disease specialists and researchers, bivalve researchers, and students alike. Diseases include Metazoan Disease, Viral diseases, Fungal Disease, and more.

  • Postbiotics

    Health and Industry
    • 1 Edición
    • Dhanasekaran Dharumadurai + 1 más
    • Inglés
    Postbiotics: Health and Industry provides a detailed overview on the fundamentals, biological and therapeutic properties, safety, and application of postbiotics in health and industry. Sections cover the fundamentals of postbiotics, which include insights on probiotic microorganisms, postbiotics, and host–microbe interaction, analysis, and characterization of postbiotics. The book goes on to delve into the different types of postbiotics and their mechanisms. Remaining sections explore various health, pharmaceutical, and industrial applications of postbiotics.

  • Immuno-oncology and immunotherapy Part A

    • 1 Edición
    • Volumen 189
    • Inglés
    Immuno-Oncology And Immunotherapy – Part A Volume 189, in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Specific chapters to this release include, Generation of transmitochondrial cybrids in cancer cells, Methods for flow cytometry analysis for tumor infiltrating cells functions and phenotype, Innovative 2D and 3D methods of tumor cells culture, and more.

  • Challenges and Solutions of Climate Impact on Agriculture

    • 1 Edición
    • Shah Fahad + 5 más
    • Inglés
    Challenges and Solutions of Climate Impact on Agriculture explores issues arising from the changing climate for agricultural plants, with a soil-focused approach. Addressing the impacts on a range of important global food crops, it looks at issues of water and temperature and their impact on soil quality for production.Presented by a global team of experts, this book will be important for researchers seeking to understand specific challenges, and means of addressing those challenges effectively and efficiently.The agriculture sector is arguably one of the most sensitive to changes in the climate. Because the climate of a region determines the nature and characteristics of vegetation and crops, any change in the mean seasonal temperature and decrease in effective precipitation can reduce productive periods for crops, risking outbreaks of pests and disease and negatively affecting global food security.

  • Sprouted Grains

    Nutritional Value, Production, and Applications
    • 2 Edición
    • Hao Feng + 3 más
    • Inglés
    Sprouted Grains: Nutritional Value, Production and Applications, Second Edition includes new chapters on sprouted grains as new plant-based protein sources, Fatty Acids Content and Profiling in Sprouted Grains, Amylase Activity in Sprouted Grains, and The Role of Sprouted Grains in Human Gut Health. As sprouted grains are one of the hottest topics in cereal and grain science, this comprehensive reference presents essential reading, from grain germination from both a genetic and physiological perspective, the nutrients and bioactive compounds present in spouted grains, equipment and technical innovations for processors and manufacturers of sprouted grains and subsequent products, and more.

  • Fungal Stress Mechanisms and Responses

    • 1 Edición
    • Volumen 129
    • Inglés
    AAM: Fungal Stress Mechanisms and Responses explores the adaptive strategies and biotechnological applications of fungi under stress conditions. This volume features an array of reviews by experts in the field, reviewing different aspects of fungal stress responses. The initial three chapters focus on stress in fungal insect pathogens, while chapters 4–6 address the impact of stressful environmental conditions on fungi used for bioremediation. The last chapter investigates the molecular aspects of copper homeostasis in human fungal pathogens. This volume offers a comprehensive collection of findings that help our understanding of fungal stress responses and their applications in agriculture, medicine, and the environment.

  • Targeted Therapy for the Central Nervous System

    Formulation, Clinical Challenges, and Regulatory Strategies
    • 1 Edición
    • Viral Patel + 3 más
    • Inglés
    Targeted Therapy for the Central Nervous System: Formulation, Clinical Challenges, and Regulatory Strategies presents research on various delivery methods of drugs to the central nervous system and brain. This volume examines targeted therapies for neurodegenerative disorders and succinctly outlines the future of drug delivery systems, highlighting significant advancements specifically relating to central nervous system delivery. This book will be of great interest to researchers working in the field of neuroscience and pharmacology as well as clinicians (pharmacists, radiologists, psychiatrists).

  • Extracellular Vesicles from Basic Research to Clinical Applications

    • 1 Edición
    • Volumen 94
    • Inglés
    Extracellular Vesicles from Basic Research to Clinical Applications, Volume 94 covers theses lipid bilayer particles containing proteins, glycoproteins, mRNA, other small RNA species, and lipids formed and released by various pathogens. Chapters in this update include Extracellular Vesicles release from protozoa parasite and animal model, EVs from parasite and biomarkers, Translational Medicine – Use of EVs as therapy, EVs and viruses and their interaction with cells, EVs and Toxoplasma gondii, EVs and Fungi, Biogenesis of EVs in parasites, Extracellular vesicles, EVs and Leishmania, EVs in neuropsychiatry, EVs and Bacteria.Other sections cover EVs and sleep deprivation, EVs and cancer, Extracellular vesicles and methods to isolation, purification, and characterization.

  • Fish Protein Hydrolysates

    From Production to Food and Nutraceutical Industry Applications
    • 1 Edición
    • Nilesh Nirmal + 3 más
    • Inglés
    Fish Protein Hydrolysates: From Production to Food and Nutraceutical Industry Applications provides the most updated and comprehensive knowledge on fish protein hydrolysate production using a variety of innovative processing techniques and technologies. This book highlights various biological activities and health benefits of fish protein hydrolysates, their food and nutraceutical industry applications, and associated safety concerns.Written by international experts in the field of fisheries and seafood processing, this book provides its readership with a wealth of recent developments and guidance on each production method, including current and emerging technologies. This book discusses the defatting and debittering aspects of fish protein hydrolysates, purification methods, trends in food product development, food and feed applications, and more. Most importantly, this book provides real-time industrial scale-up process, commercialization, safety, and regulatory issue of fish protein hydrolysate as a food ingredient.Fish Protein Hydrolysates: From Production to Food and Nutraceutical Industry Applications is a valuable resource for fish processing industries, researchers, or scientists to update their knowledge on production techniques, bittering issues of fish protein hydrolysates, and scale-up processes. In addition, this is a valuable source for academic scholars and students to keep up to date with the current changes and improvements in fish protein hydrolysate production and applications in the food industry.

  • Progress in Medicinal Chemistry

    • 1 Edición
    • Volumen 63
    • Inglés
    Progress in Medicinal Chemistry, Volume 63 highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Specific chapters in this release include Harnessing conformational drivers in drug design, Recent Advances in the Medicinal Chemistry of Heterobifunctional Derivatives for Protein Homeostasis, and A Decade of Antimalarial Drug Discovery: New Targets, Tools and Molecules.

  • The Fundamentals of Stereoelectroencephalography

    • 1 Edición
    • Patrick Chauvel + 3 más
    • Inglés
    Gain confidence and expertise with stereoelectroencepha... (SEEG) as a presurgical method for epilepsy with this helpful resource. Edited and written by leading experts in the field, Stereoelectroencepha... teaches the scientific and medical bases of SEEG through its essential disciplines (anatomy, biophysics, electrophysiology, and cognitive and behavioral neuroscience) and their interrelations. It fully covers the basic and clinical aspects of the pharmaco-resistant epilepsies investigated with SEEG and their surgical indications.

  • Cell and Gene Therapies for Neurologic Diseases

    • 1 Edición
    • Volumen 205
    • Inglés
    Cell and Gene Therapies for Neurologic Diseases, Volume 205 comprehensively covers the scientific background, translational efforts, clinical developments and registered biologics that have entered into clinical practice. Coverage includes types of therapies available and in development, and best practice uses for a variety of neurological disorders including Parkinson’s, Huntington’s, ALS, stroke, spinal cord RP, demyelination, and epilepsy. As the emergence of gene and cellular therapeutics has changed the clinical landscape for a variety of disorders, and is now ready to do so for neurological diseases, these therapeutic modalities currently complement, and may in time, supplant small molecule drugs.

  • Neuropsychology for Neurologists, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 42-4
    • Jane Paulsen + 1 más
    • Inglés
    In this issue of Neurologic Clinics, guest editors Drs. Jane S. Paulsen and Carissa Gehl bring their considerable expertise to the topic of Neuropsychology for Neurologists. Top experts provide an overview of neuropsychological assessment that extends beyond mental status examination to facilitate diagnostic considerations, clinical decision making with regarding to critical life skills, and suggestions for rehabilitation. This issue also includes characterization of typical neuropsychological features associated with specific illnesses/injuries and consideration of behavioral signs and symptoms, functional capacity, and quality of life for individuals with these diagnoses.

  • Application of Emerging Technologies and Strategies to Extract Bioactive Compounds

    • 1 Edición
    • Paulo Eduardo Sichetti Munekata
    • Inglés
    Application of Emerging Technologies and Strategies to Extract Bioactive Compounds, Volume Three in the Developments in Food Quality and Safety series, is the most up-to-date resource covering trend topics such as advances in the analysis of toxic compounds and control of food poisoning, food fraud, traceability and authenticity, revalorization of agrifood industry, natural antimicrobial compounds and application to improve the preservation of food, non-thermal processing technologies in the food industry, nanotechnology in food production, and Intelligent packaging and sensors for food applications.Chapter... in this release explore the latest developments in the application of each technology, such as ultrasound, microwave, high-pressure, pulsed electric fields, ohmic, uv and ir heating, extrusion, and solar energy assisted extractions, along with membrane technologies and alternative solvents for green extraction. The series is edited by Dr. José Manuel Lorenzo and authored by a team of global experts in the field.

  • Next Generation eHealth

    Applied Data Science, Machine Learning and Extreme Computational Intelligence
    • 1 Edición
    • Miltiadis Lytras + 3 más
    • Inglés
    Next Generation eHealth: Applied Data Science, Machine Learning and Extreme Computational Intelligence discusses the emergence, the impact, and the potential of sophisticated computational capabilities in healthcare. This book provides useful therapeutic targets to improve diagnosis, therapies, and prognosis of diseases, as well as helping with the establishment of better and more efficient next-generation medicine and medical systems. Machine learning as a field greatly contributes to next-generation medical research with the goal of improving medicine practices and medical Systems. As a contributing factor to better health outcomes, this book highlights the need for advanced training of professionals from various health areas, clinicians, educators, and social professionals who deal with patients. Content illustrates current issues and future promises as they pertain to all stakeholders, including informaticians, professionals in diagnostics, key industry experts in biotech, pharma, administrators, clinicians, patients, educators, students, health professionals, social scientists and legislators, health providers, advocacy groups, and more. With a focus on machine learning, deep learning, and neural networks, this volume communicates in an integrated, fresh, and novel way the impact of data science and computational intelligence to diverse audiences.

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