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Elsevier

Libros en Ciencias de la Vida

  • Allergic Asthma Immunopathogenesis

    Immunopathology of the Allergic Asthma
    • 1 Edición
    • Seyyed Shamsadin Athari + 1 más
    • Inglés
    Allergic Asthma Immunopathogenesis: Immunopathology of the Allergic Asthma presents a new glance to the allergic asthma pathophysiology by focusing on the immunopathogenesis and allergo-inflammation mechanisms of asthma and cell signaling pathways that can be used for various research purposes, including the design of anti-asthma treatment and target therapy for scientists and researchers. As asthma is a chronic, complicated airway disease whose mortality and morbidity rates have increased worldwide, some common treatments for asthma cannot control it nor even prevent simple inflammation and relieve shortness of breath. Thus, understanding its molecular pathways and pathophysiology is required in order to better understand the disease.

  • Cannabis and its Derivatives

    Guide to Medical Application and Regulatory Challenges
    • 1 Edición
    • Rahul Shukla + 3 más
    • Inglés
    Cannabis and its Derivatives: Guide to Medical Application and Regulatory Challenges summarizes the current state of research and clinical pharmacology of cannabis-based therapeutics, along with associated regulatory frameworks. Sections cover historical, botanical, and taxonomical platforms of cannabis, chemical derivatives of the cannabis plant, a literature review of therapeutic applications, the biological fate of cannabis and its metabolic products, pain management, neurological disorders, cancer management, interactions with other drugs, veterinary applications, and the adverse effects of Cannabis overuse in humans.The book's final section is devoted to discussions around regulatory challenges and future considerations. This is the ideal reference pharmaceutical scientists, clinicians, and academic researchers who want access to updated information on the therapeutic applications of cannabis and its derivates. Corporate researchers will also benefit from this book’s presentation of the associated regulatory environment.

  • Cancer Therapy

    Potential Applications of Nanotechnology
    • 1 Edición
    • Surendra Nimesh + 2 más
    • Inglés
    Cancer Therapy: Potential Applications of Nanotechnology provides readers with a compendium of all the latest research work in cancer therapeutics, including an emphasis on work in nanotechnology and polymeric nanoparticles. While there have been a large number of ongoing research projects and publications on the treatment of cancer, there is a limited number of books related to nanotechnology, especially those with an emphasis on polymeric nanoparticles in cancer therapy. This title enlightens researchers and students and provides exhaustive knowledge on the topics covered.

  • Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies

    Shaping Digital Future
    • 1 Edición
    • Patricia Ordonez de Pablos
    • Inglés
    Digital Healthcare in Asia and Gulf Region for Healthy Aging and More Inclusive Societies: Shaping Digital Future provides insight to the potential of advanced information technologies to build stronger healthcare systems, better quality healthcare services, and more resilient societies. The book covers two important regions: Gulf Region (Bahrein, Kuwait, Oman, Qatar, and UAE) and Asia, and explores how these countries develop policies for healthy aging and how digital tools can serve these goals. This book delivers a collection of relevant, innovative research works on digital healthcare, with four main goals: (1) to cover two geographical regions (Asia and Gulf Region) with important advances in digital healthcare; (2) to present case studies in the field of IT and digital health during the pandemic and analyze the lessons from these studies; (3) to evaluate the latest advances in the field of digital healthcare (especially Artificial Intelligence [AI], Big Data, Blockchain, and 5G); and (4) to discuss implications for main stakeholders (patients, doctors, IT experts, directors, and policy managers) and recommendations for policy makers in these two regions and elsewhere.

  • Advanced Techniques of Honey Analysis

    Characterization, Authentication, and Adulteration
    • 1 Edición
    • Gulzar Ahmad Nayik + 2 más
    • Inglés
    Advanced Techniques of Honey Analysis: Characterization, Authentication, and Adulteration presents an overview of honey, including its classification, composition, safety, present status, quality issues, and prospects before delving into honey adulteration and presenting various methodologies for honey analysis. Broken into fourteen chapters, this book explores the physiochemical, bioactive compound, aroma, microbial, thermal, and rheological analysis and properties of honey. It also considers infrared spectroscopy, nuclear magnetic resonance, and Raman spectroscopy methods. High-performance liquid chromatography, gas chromatography and GC-MS methods are also highlighted.Written for food scientists and those working in honey industries and related fields, this book will be a welcomed resource for all who wish to play a role in mitigating honey fraud.

  • Bioactive Microbial Metabolites

    Scope and Challenges
    • 1 Edición
    • Vaibhav Mishra + 2 más
    • Inglés
    Bioactive Microbial Metabolites: Scope and Challenges not only focuses on the identification, separation and purification of bioactive metabolites, the book also provides an understanding of the metabolic pathways for bioactive metabolites production that play an important role in modern healthcare as frontline treatments for many diseases. This is a valuable reference for research students, academicians and scientists in environmental microbiology and biotechnology, and for industry personnel related to microbiology/ biotechnology. The science discussed herein plays an important role in expanding the market of antibiotics, food and agriculture but also offers eco-friendly, safer and profitable solutions to respective industries.

  • Targeting Signaling Pathways in Solid Tumors Part B

    • 1 Edición
    • Volumen 386
    • Inglés
    Targetting Signaling Pathways in Solid tumour Part B, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Biological Insights of Multi-Omics Technologies in Human Diseases

    • 1 Edición
    • Aarif Ali + 3 más
    • Inglés
    Biological Insights of Multi-Omics Technologies in Human Diseases provides detailed information about the basics of multi-omic technologies, including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters, this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives.The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Vitamin D and health

    • 1 Edición
    • Volumen 109
    • Inglés
    Vitamin D and Health, Volume 109 reviews the versatility of vitamin D in enhancing the immune system and its potential role in combating many chronic diseases. While vitamin D’s role in enhancing bone health is well established, recent studies demonstrated the safety and efficacy of peri-operative vitamin D supplementation in cardiac patients and its impact on post-operative outcomes. Chapters in this new release include discussions on Vitamin D and Immune Function, Vitamin D and Bone Heath, Vitamin D and Cardiovascular Disease, Vitamin D and Cancer, Vitamin D and Diabetes, Vitamin D and Neurological Diseases, Vitamin D and Celiac Disease, and much more.

  • Mechanoluminescence in Organic and Inorganic Compounds

    Basic Concepts, Instrumentation, and Applications
    • 1 Edición
    • Vikas Dubey + 3 más
    • Inglés
    Mechanoluminescence in Organic and Inorganic Compounds: Basic Concepts, Instrumentation, and Applications provides a comprehensive overview of mechanoluminescence for newly qualified researchers and scientists across multiple related fields. It serves as a guide for budding scientists to advance in the field through various applications covered in this book, such as energy, mechanics, medicine, and optics. This reference shines light on the pros and cons of utilizing organic or inorganic mechanoluminescent materials, making it a handy tool for researchers worldwide involved in luminescence and applications such as optoelectronics, sensors, forensics, displays, energy harvesting, and smart robotics. The editors and their expert contributors summarize these applications, making it a valuable resource for academics, researchers, and those working in industry.Mechanolumi... in Organic and Inorganic Compounds contains broad coverage, which progresses from theory to applications, serves as a complete reference of global research and experience, which will work to inform and guide the development of more efficient devices for the future.

  • New Approach for Drug Repurposing Part A

    • 1 Edición
    • Volumen 205
    • Inglés
    New approach for drug repurposing represents drug discovery and development which is a tedious process that requires 10-15 years of time, investments up to $1-2 billion, and have high risk of failure to enter into market for clinical applications. As the drugs has to pass through number of developmental phase, the likelihood for a drug to be approved from phase I clinical trial to United States of Food and Drug Administration (USFDA) approval is less than 10%. More than 90% of drugs failed in due to toxicity, efficacy and clinical trials. Drug repurposing is one of the roadway to accelerating drug discovery and development for treating disease and thus to providing better quality of life. This volume covers an overview of drug repurposing, novel methods, mechanism of action, lab on chip for drug repurposing, computational biology, system biology, artificial intelligence and machine learning for drug repurposing, target identification, target mining, high throughput drug screening, clinical trial of repurposed drug, repurposed biologics, and regulatory consideration and intellectual property right of repurposed drug. This volume highlights a number of aspects of the drug repurposing that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

  • Pictorial Atlas of Neuroradiological Signs

    • 1 Edición
    • Athena Sharifi-Razavi + 2 más
    • Inglés
    Pictorial Atlas of Neuroradiological Signs examines various brain scans in order to create a useful guide for clinicians and students. Using images of diseases and other conditions, this atlas is designed to identify various signs as well as explain what the underlying reason for the presentation of such anomalies on brain scans and images. This book will be most useful to clinicians in neurology and students who are studying neuroradiology. Those with an interest in various branches of neuroscience or radiology might also find this book a useful tool.

  • Brains and Machines: Towards a unified Ethics of AI and Neuroscience

    • 1 Edición
    • Volumen 7
    • Inglés
    Brains and Machines: Towards a unified Ethics of AI and Neuroscience provides a comprehensive overview of concepts and ethical issues at the intersection of two emerging technological trends in the 21st century: AI and neurotechnology. In line with recent advances across both fields, debates about philosophical, ethical, regulatory and social issues raised by neuroscience and AI have considerably expanded in the past decade. Yet, despite many intersections and fruitful interactions between the two scientific domains, ethical debates about neuroscience and AI have mostly moved in parallel. This volume assembles voices from various disciplines to provide a more unified view and offer novel perspectives on two complementary lines of discourse. The volume provides scientific background by outlining the state of the art of applying AI in the field of neuroscience and discussing instances where findings and debates from neuroscience provide cues and inspiration to the study of AI. Based on this background, the book then addresses conceptual frameworks, identifies ethical challenges at the intersection of neuroscience and AI, and highlights challenges and opportunities of finding common ground in interdisciplinary settings.

  • Regulatory T cells and Autoimmune Diseases

    • 1 Edición
    • Mitesh Kumar Dwivedi + 1 más
    • Inglés
    Regulatory T Cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic applications. In particular, this book deals with various Treg-based mechanisms that can lead to autoimmune disease and covers different aspects linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies.This book specifically focuses on Treg-based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood and blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, this book covers vaccine-induced effects on the functioning of Tregs and development of CAR Treg therapy for autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. This book is carefully designed to meet the requirements of both basic and advanced researchers in the area and provide new dimensions and insight into regulatory T cells’ role in autoimmune disease pathogenesis and therapy.

  • Pharmacology in Drug Discovery and Development

    Understanding Drug Response
    • 3 Edición
    • Terry P. Kenakin
    • Inglés
    Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

  • Advances in Artificial Intelligence

    Biomedical Engineering Applications in Signals and Imaging
    • 1 Edición
    • Kunal Pal + 2 más
    • Inglés
    Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of arti­ficial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical ­ eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.

  • Neuroscience Without Representations

    Building a Brain-in-a-World View
    • 1 Edición
    • Óscar Vilarroya
    • Inglés
    In Neuroscience Without Representations, an Open Access book, Oscar Vilarroya addresses the notion of “representation” as used in expressions like “neural representation” or “mental representation”. This concept is fundamental in neuroscience, yet there remains no clear, universally accepted view on what it means for a nervous system to represent something, what constitutes a neural activity as a representation, and what is being re-presented.The book lays the foundation for a non-representational view of brain function. Building upon György Buzsáki’s critique of the theoretical framework underlying current cognitive neuroscience, Vilarroya argues that disciplines such as embodied and embedded cognition—collective... known as ‘4E cognition’—are driving a paradigm shift in our understanding of animal cognition.Rather than grounding cognition solely in representations, the author proposes an alternative: understanding cognition as enaction—the meaningful engagement of an organism to address situational requirements. The book supports this approach through detailed analyses of recent studies.

  • Banana Peels Valorization

    Sustainable and Eco-friendly Applications
    • 1 Edición
    • Mejdi Jeguirim + 1 más
    • Inglés
    Banana Peels Valorization: Sustainable and Eco-friendly Applications provides a global overview of world production, physicochemical and microbiological characteristics of Banana Peels and the various pathways for their valorization, considering the advantages, disadvantages and factors impacting on each way of valorization. Each chapter deals with sustainable applications based on the sector category. Such structure helps the audience from a specific field to easily identify the specific application. Successful case study of a banana processing by-products valorization is also presented. Written by a team of interdisciplinary experts, this is the ultimate valuable resource for agricultural or food engineers who work in the banana groves and in the banana processing industry, and also for Researchers working in correlated areas of food, environmental and energy fields.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 127
    • Inglés
    Advances in Applied Microbiology, Volume 127 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Nucleic acid associated mechanisms in immunity and disease

    • 1 Edición
    • Volumen 161
    • Inglés
    Advances in Immunity volume 161 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Plant Biomass Applications

    Materials, Modification and Characterization
    • 1 Edición
    • Mohammad Jawaid + 2 más
    • Inglés
    Plant Biomass Application: Materials, Modification and Characterization focuses on the unique properties associated with plant biomass, from their biodegradable, non toxic, and safe for handling characteristics to their potential in developing sustainable, climate protecting products. The book covers all aspects of plant biomass materials opportunities, with a focus on the value-added product generated from plant biomass such as polymers, composites, transportation fuels, chemical intermediates/bulk chemicals, or sources of heat and generated power. The conversion of plant biomass into materials product such as plastics, fabrics, and carpets and specialty chemicals presents exciting possibilities for replacing traditionally used fossil fuels. Sections in this new release provide in-depth discussion on the materials derived from plant biomass and their current and potential future applications. Leading researchers from industries, academics, government, and private research institutions across the globe provided insights, making it an important reference for researchers and academics seeking to maximize plant biomass potential.

  • Phylogenomics

    Foundations, Methods, and Pathogen Analysis
    • 1 Edición
    • Igor Mokrousov + 1 más
    • Inglés
    Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 120
    • Inglés
    Advances in Clinical Chemistry, Volume 120, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.

  • Immunology for Engineers

    • 1 Edición
    • Volumen 140
    • Inglés
    Immunology for Engineers, Volume 140 consists of chapters from stalwarts of the field, covering topics such as antibody engineering, adjuvant requirement and its methodology for assessment, and the need to develop immunotherapy, etc. Chapters covered in this volume discuss Current Status and Future Prospective of Breast Cancer Immunotherapy, Engineering high affinity antigen binders- beyond antibodies, Platelets and Inter-Cellular Communication in Immune Responses: Dialogue with both Professional and Non-Professional Immune Cells, Chimeric Antigen Receptor (CAR) T cell-based cancer immunotherapy: A boon for cancer-free life, and Molecular insights and promise of Oncolytic Virus based Immunotherapy.

  • Rang y Dale. Farmacología

    • 10 Edición
    • James M. Ritter + 4 más
    • Español
    Nueva edición del texto clásico en Farmacología y de referencia para los estudiantes de Medicina en el que se aborda de forma exhaustiva, pero clara y organizada el mecanismo de acción de los fármacos más comúnmente usados, tanto a nivel molecular o celular, como de los mecanismos fisiológicos sobre los que actúan.Se ha mantenido la organización general del libro, dividido en 6 grandes secciones en las que se ofrece una descripción de los efectos y usos de los diferentes fármacos junto con su acción sobre las vías de señalización subyacentes a todos los procesos fisiológicos que ocurren en el ser humano. En cuanto a las novedades, si bien todos los capítulos se han actualizado, algunos de ellos han sufrido grandes cambios. Así cabe destacar: Cap 5 (se han incluido un mayor número de fármacos RNA), Cap 24 (recientes avances en la medición de la presión de oxígeno), Cap 40 (se ha puesto el foco en el Alzheimer y la demencia vascular y la asociada a los cuerpos de Levy), Cap 43 (nueva sección destinada al tratamiento del dolor crónico), Cap 51 (nuevos diagramas que ilustran los lugares de acción de los antibióticos a nivel de los ribosomas), Cap 53 (información sobre el modo de replicación de los retrovirales y una sección específica de Covid19) y Cap 57 ( gran y amplia cobertura de los nuevos fármacos anticancerosos). Se ha introducido dos nuevos capítulos. Uno de ellos dedicado a la Farmacología ocular y otro dedicado al tratamiento farmacológico de la migraña en el que se incluyen los nuevos antagonistas de CGRP y su uso profiláctico para la migraña. La nueva edición incluye acceso al e-book en español en el que se incluye contenido adicional (casos clínicos y preguntas de autoevaluación) también en español.

  • Starch in Food

    Structure, Function, and Applications
    • 3 Edición
    • Lars Nilsson
    • Inglés
    Starch in Food: Structure, Function and Applications, Third Edition is now fully updated with eleven new chapters covering "hot" areas for starch applications, such as starch-based pickering emulsifiers, starch for structuring gluten-free bread products, and starch microspheres for encapsulation of probiotic bacteria. Sections illustrate how plant starch can be analyzed and modified, including chapters on analysis of starch molecular structure, molar mass and size, the relationship between structure and digestion of starch, sources of starch, including new chapters on cereal, root and tuber and pulse starches, and starch applications, with a new chapter on utilizing starches in product development, in baked products and in gluten-free bread. Starch selection is one of the most complex areas for a product developer, yet starch is key to solving formulation challenges when developing products to meet many of the emerging consumer trends. This book aids the end user on acquiring knowledge on fundamental starch aspects, such as granular and molecular structure and properties, analysis, biosynthesis and general functionality of starch in foods.

  • Handbook of Plant-Based Meat Analogs

    Innovation, Technology and Quality
    • 1 Edición
    • Gokare A. Ravishankar + 3 más
    • Inglés
    Handbook of Plant-Based Meat Analogs: Innovation, Technology and Quality presents the growing opportunities and challenges of meat substitutes from plant-based resources. Addressing core topics from source ingredients to consumer acceptance, it provides a comprehensive starting point for those seeking to explore sustainable meat alternative products. To date, the full potential of plant-based meat products has been underexplored, underutilized, and underrepresented.Thi... book provides the most up-to-date information on plant-based meat analogs, sources of ingredients, industrial processes, large-scale production, and health benefits, including safety and regulatory aspects and environmental implications.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 124
    • Inglés
    Advances in Parasitology Volume 124, the latest release in this esteemed series, highlights new advances in the field, with this new release including chapters on Geomorphological determinants and geospatial analyses of mosquito habitat for control and elimination studies of malaria in Africa, Immunology and Pathology of Echinostomes and other Intestinal Trematodes, PfEMP1 – Still of key importance in Plasmodium falciparum malaria immunity and pathogenesis, and more.

  • Grapevine

    From Origin to the Vineyard
    • 1 Edición
    • Volumen 110
    • Inglés
    Advances in Botanical Research: From Origin to the Vineyard, Volume 110 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Grapevine origin and diversity, Climate change implications on the geography of viticulture, Canopy and soil management strategies insights into overcome abiotic stresses in grapevine, Grapevine defense mechanisms when challenged by pathogenic fungi and oomycetes, Management strategies for reducing pesticide use against diseases caused by fungi and oomycetes in grapevine, The Role of Plant Breeding in grapevine production, and New biotechnological tools for grapevine improvement.

  • An Integrated Guide to Human Drug Metabolism

    From Basic Chemical Transformations to Drug-Drug Interactions
    • 1 Edición
    • Mark Ashton + 3 más
    • Inglés
    An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines, and other drugs. Each of the human metabolic processes are covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (age-related dosage adjustments, routes of administration, and personalized medicines). Appropriate for use in the classroom or for self-study, this book is for students and researchers needing a reference for interdisciplinary research in drug interactions.Metabol... is at the center of personalized medicine, as it is a governing factor in the response of the patient to a drug. For example, does the patient express the genes, and so enzymes, which are responsible for the metabolism of a drug? Do they express the genes responsible for the bioactivation of a prodrug into its active form? Examples of clinically used agents for which metabolic phenotyping is essential will be used to highlight the increasing necessity for understanding the genetic profile of individual patients. This book includes questions and answers to gauge learning of each chapter, real-life case studies, and the basic science as a basis for the discussion of clinical aspects.

  • Bioreactor Design Concepts for Viral Vaccine Production

    • 1 Edición
    • Surajbhan Sevda + 1 más
    • Inglés
    Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production.

  • Advanced Biologic Drugs and Manufacturing Process

    • 1 Edición
    • Basanta Kumara Behera
    • Inglés
    Advanced Biologic Drugs and Manufacturing Process explains biologic drugs, their pharmaceutical charters, and their significance in curing life-threatening chronic diseases. It also provides the latest information on the use of biological drugs for the treatment of numerous diseases and conditions and their most advanced therapies available, including how biologics have impacted cancer therapy, delayed or reversed the course of immune-related conditions, and changed the lives of those with rare chronic diseases. In addition, the book explains how immunotherapy is used for the treatment of diseases by activating or suppressing the immune system.Scientists working on the front lines in the biotechnology industry are provided with an overview on stable production processes and how to monitor the value chain transfer process of biologic drug for better return, in terms of profit. The book also helps researchers and academics on how to develop and update protocols related to testing, quality control, and quality assurance to obtain highly purified biopharmaceuticals or vaccines.

  • Environmental Pollution and Type 2 Diabetes Mellitus

    • 1 Edición
    • Sultan Ayoub Meo
    • Inglés
    Environmental Pollution and Type 2 Diabetes Mellitus elucidates on the global impact of environmental pollution and how it increases diabetes mellitus. Swift urbanization and the industrial revolution have increased environmental pollution to a hazardous level. Environmental pollution is a leading risk factor for several well-known diseases. This book opens venues for students, physicians, researchers, the science community, and policymakers to enhance their knowledge about environmental pollution, weather conditions, climate change, and their impact on insulin resistance and mechanisms allied to Type 2 diabetes mellitus (T2DM).Moreover, this book will provide knowledge about the green space environment and its impact on T2DM.

  • Vertebrate Pattern Formation

    • 1 Edición
    • Volumen 159
    • Inglés
    Vertebrate Pattern Formation, Volume 159 in the Current Topics in Developmental Biology series, highlights advances in the field, with this volume presenting interesting chapters on timely topics, including Hox genes patterning the vertebrate body, Endodermal patterning, The use of organoids/gastruloid... to understand development, Cell shape and movements controlling development, Neural crest and placodes in vertebrate development, Patterning of the neural tube, Non-canonical Wnt signaling in axial extension, The control of transitions along the main body axis, Emergence of a left-right symmetric body plan in vertebrate embryos, Formation of the vascular system, Generation of patterns in the paraxial mesoderm, and more.

  • Bioremediation of Emerging Contaminants from Soils

    Soil Health Conservation for Improved Ecology and Food Security
    • 1 Edición
    • Prasann Kumar + 4 más
    • Inglés
    Bioremediation of Emerging Contaminants from Soils: Soil Health Conservation for Improved Ecology and Food Security deals with current challenges of sustainable soil health using eco-friendly approaches. This book provides ways of reducing the chemical burden on the soil by maintaining balance in terms of society, environment, and economy, which are considered basic pillars of sustainability.Desig... to highlight soil health best practices for both environmental and agricultural sustainability, these approaches are also considered important for improving global food security by ensuring safe growing conditions for crops for food and feed. Presented in two parts, this book first highlights emerging contaminants and their sources. The second part explores a variety of steps and tools for addressing contaminated soils, including bio- and phytoremediation options. Case studies in each part provide real-world insights for practical application.

  • Nanobiotechnology for Food Processing and Packaging

    • 1 Edición
    • Jay Singh + 4 más
    • Inglés
    Nanobiotechnology for Food Processing and Packaging covers nanomaterials' application as an eco-friendly, greener, cost-effective and easy handling and management approach that can help prevent various high-level physical, biological and chemical contamination in foodstuff. Written by experts from a multidisciplinary perspective, each chapter addresses nanomaterials' application as a sustainable tool for the management of uncountable food processing and packaging challenges. Sections focus on nanobiotechnology in processing and packaging, considering food quality, safety and management aspects. The book also highlights various preparative methods and antimicrobial/antifu... activities, including the mechanism of the antimicrobial action of various bionanocomposites and food toxin detection nanobiosensor nano additives.Other sections cover possible food toxin detection, food packaging, and materials such as nanomaterials, nanocomposites, carbon-based nanomaterials, polymer-based nanocomposites and various binary and tertiary nanocomposites and their mechanistic approach.

  • Current Omics Advancement in Plant Abiotic Stress Biology

    • 1 Edición
    • Deepesh Bhatt + 3 más
    • Inglés
    Current Omics Advancement in Plant Abiotic Stress Biology investigates the causal molecular factors underlying the respective mechanisms orchestrated by plants to help alleviate abiotic stress. Despite available knowledge of abiotic stresses in crop plants and high throughput tools and biotechnologies, in this book, a systematic effort has been made for integrating omics interventions across major sorts of abiotic stresses with special emphasis to major food crops infused with detailed mechanistic understanding, which would furthermore help contribute in dissecting the interdisciplinary areas of omics-driven plant abiotic stress biology in a much better manner.It focuses on the integration of multi-OMICS biotechnologies in deciphering molecular intricacies of plant abiotic stress, namely drought, salt, cold, heat, and heavy metals in major C3 and C4 food crops. Together with this, the book provides updated knowledge of a common and unique set of molecular intricacies playing a vital role in coping up severe abiotic stresses in plants deploying multi-OMICS approaches.

  • Progress and Prospect of Nanocarriers

    Design, Concept, and Recent Advances
    • 1 Edición
    • Sushil K. Kashaw + 2 más
    • Inglés
    Progress and Prospect of Nanocarriers: Design, Concept, and Recent Advances examines the different nanocarriers that are currently being developed for specific applications in biomedical drug delivery, disease management, diagnosis and therapy. Nanosized drug delivery systems have gained tremendous amounts of clinical interest due to their effective bio-distribution and enhanced pharmacokinetic and selective targeting capability which results in high therapeutic potential, low side effects, and the generation of cost-effective drug delivery systems. Numerous effective nanocarriers have been evolving, including polymeric nanoparticles, liposomes, microspheres, dendrimers, and carbon nanotubes.This book is a helpful reference for scientists and students in the fields of drug delivery, biomaterials and nanomedicine, as well as scientists and engineers in industrial disciplines of drug delivery and drug formulation.

  • Biocatalysis in Asymmetric Synthesis

    • 1 Edición
    • Gonzalo De Gonzalo + 1 más
    • Inglés
    Biocatalysis in Asymmetric Synthesis, a new volume in the Foundations and Frontiers of Enzymology series, offers an applied discussion on synthesizing biological catalysts using asymmetric synthesis for varying applications. Here, global experts in the field analyze a wide variety of biocatalysts and their physical states, process conditions for their asymmetric synthesis, solvents required during synthesis, and even downstream procedures for the recovery of final products. The book adopts an interdisciplinary approach, merging fundamental biology and its synthetic applications across industries with a wide range of practical examples, from directed evolution to biotransformation and production of novel enzymes and non-conventional catalysts. Throughout the book, the impact and application of biocatalysis in sustainable processing is considered in-depth. This book will also help non-experts in biocatalysis to apply this knowledge in their own research, providing a thorough overview of the ways asymmetric biocatalytic approaches may be adapted for different disciplines and downstream products.

  • Integrative Omics

    Concept, Methodology, and Application
    • 1 Edición
    • Manish Kumar Gupta + 3 más
    • Inglés
    Integrative Omics: Concept, Methodology and Application provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference provides systemic ‘step-by-step’ coverage that begins with basic concepts from Omic to Multi Integrative Omics approaches followed by applications and emerging and future trends. All areas of Omics are covered, including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics, technology policy, and society research. This book covers recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science.

  • Cranial Surgery - Part 2

    • 1 Edición
    • Volumen 285
    • Inglés
    This is a study of the evolution of the principles and techniques of cranial surgery from Hippocrates to the nineteenth century. The methods of conveying information by text and image are considered.

  • Microbial Vitamins and Carotenoids in Food Biotechnology

    Novel Source and Potential Applications
    • 1 Edición
    • Syed Amir Ashraf + 1 más
    • Inglés
    Microbial Vitamins and Carotenoids in Food Biotechnology: Novel Source and Potential Applications provides important insights to help readers understand the molecular mechanisms involved in the microbial biosynthesis of vitamins and carotenoids. The book's chapters put forward all the latest advancements concerning the production and applications of microbial vitamins and carotenoids. It also provides a sustainable alternative to chemically synthesized compounds and presents wide coverage on the most promising sources of vitamins and carotenoids in food and pharmaceutical industries.This is a complete and unique resource beneficial for the scientific communities as well as food science and nutrition research students.

  • Colorimetric Sensors

    Techniques to Measure Food Safety and Quality
    • 1 Edición
    • Haroon Elrasheid Tahir + 3 más
    • Inglés
    Colorimetric Sensors: Techniques to Measure Food Safety and Quality explores the latest advancements in colorimetric sensors/indicators and their applications. It consolidates state-of-the-art developments and current approaches in the fabrication of colorimetric sensors/indicators for cutting-edge applications. This book documents the principles of colorimetric sensors, sensor fabrication and characterization, sensitivity and detection limits of colorimetric sensors based on natural pigments, synthetic dyes, and nanotechnologies, as well as safety, quality controls, and regulatory aspects, followed by an assessment of their safety and quality. In addition, global trends in the application of colorimetric sensors in monitoring food freshness, challenges, marketing, and potential future development applications are addressed in detail. How the applications of colorimetric sensors/indicators in the analysis of cereal and cereal-based products, meat and meat products, liquid and semiliquid foods, food authentication, food toxicants, and pathogens, among others, is also discussed. This book can be used as a textbook for graduate students, a reference book for medical biologists, nanobiotechnologists... nanoengineers, agricultural scientists, and general biologists, and an inspiration for industrialists and policymakers studying smart nanomaterials. Graduate students and food scientists of all levels will also benefit.

  • Encyclopedia of Sustainable Technologies

    • 2 Edición
    • Martin Abraham
    • Inglés
    While technological advancement leads to societal benefits in terms of economic growth, it also brings with it challenges in its impact on the environment or human health. Sustainable development seeks a uniform means of comparing the economic benefits with the environmental and health costs associated with the implementation of a new technology.This revised encyclopedia investigates sustainability initiatives across a range of industries, providing insight into future opportunities for technological development. A broad spectrum of human challenges have only become more intense since publication of the first edition. For example, climate change is now observed across the globe as a contributor to large scale weather events, including extreme drought in Australia, intense wildfires in California, and flooding along the great rivers of Africa, North and South America. Land in the Amazon rain forest is destroyed to provide increased cropland, contributing to climate change. Expansion of the use of biomass as a raw material in chemical processing leads to food shortages. In many cases, these challenges have the greatest impact on the poorest nations, and the most polluting manufacturing facilities are located in the poorest communities, demonstrating social justice challenges.Encyclope... of Sustainable Technologies, Four Volume Set provides a comprehensive analysis of the challenges of modern technology, and the innovations that are leading to better use of limited resources and improved resiliency as we learn to adapt to a changing world. Each chapter examines in depth a technological solution to support a specific human need, evaluates it relative to its impacts on the environment and human health, and considers the social justice issues underlying its development.The new edition provides a stronger link between manufacturing and climate change, updates on new technologies for the generation, distribution and storage of energy, new concepts in resiliency and modularity that have changed manufacturing and chemical processes, and emphasizes the trade-offs required to obtain desired products while minimizing environmental impact.

  • Clinical Genomics

    A Guide to Clinical Next Generation Sequencing
    • 2 Edición
    • Shashikant Kulkarni + 1 más
    • Inglés
    Clinical Genomics, Second Edition is a comprehensive, practical reference [AN1] designed specifically for laboratory directors, clinical medical directors, and genomic medicine professionals. Edited by renowned genomic pathology leaders Kulkarni and Roy, this updated edition offers clear guidance on the current technical, bioinformatic, clinical, regulatory, and reimbursement considerations involved in implementing next-generation sequencing technologies within clinical molecular diagnostic laboratories.Structu... for ease of reference, this book covers targeted gene sequencing methods, whole exome/genome approaches, emerging technologies such as long-read sequencing, and critical considerations for assay validation. Detailed sections address bioinformatics workflows, variant detection and interpretation methodologies, integration with clinical informatics systems, and essential IT infrastructure, including cloud-based solutions.This book also thoroughly addresses practical topics essential to laboratory management, such as regulatory compliance, ethical frameworks, billing strategies, and reimbursement paradigms, helping directors navigate the evolving landscape of genomic diagnostics.

  • Unit Operations in Food Grain Processing

    • 1 Edición
    • C.K. Sunil + 4 más
    • Inglés
    Unit Operations in Food Grain Processing covers theory and principles as well as best practices in cleaning, grading, drying, storage, milling, handling, transportation, and packaging of grains. The book begins with an overview of grain types, grain structure and composition, and engineering properties of different grains. It then moves into the aspects of processing. It reviews best practices in processing rice, wheat, pulses, oilseeds, millets, and pseudocereals. The book discusses value addition methods, products of grains, and waste and by-product utilization from grains. These discussions outline equipment and machinery needed, different methods of operations for various grains, and advances in grain processing as well as grain waste and by-product utilization.The book has 18 chapters in total. Each chapter discusses principles, design, illustrations, advances, and challenges to aid in understanding. Therefore this book is a valuable reference material for academicians, researchers, consultants, manufacturers, and practitioners in the field of food processing.

  • Innovating Health Against Future Pandemics

    • 1 Edición
    • Simona Mellino + 3 más
    • Inglés
    Innovating Health Against Future Pandemics covers the key aspects which drive heterogeneity in an individual's response to COVID-19, including age, sex, genetic makeup, immune responses, comorbidities, and viral strains/loads. This book also reviews the case examples from other disciplines to highlight areas where precision medicine and AI could be applied for the improvement of pandemic management. This includes research, primary and secondary prevention, isolation/tracking, hospitalization and patient management, diagnosis, and treatments. Lastly, drawing on past experiences for each of the areas this book provides practical recommendations to manage future pandemics.COVID-19 offered an unprecedented occasion to test the impact of digitally enabled solutions within precision medicine for public health and for accelerating their deployment and adoption.

  • Early and Late Presentation of Physical Changes of Puberty: Precocious and Delayed Puberty Revisited, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 53-2
    • Peter A. Lee + 1 más
    • Inglés
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Peter A. Lee and John S. Fuqua bring their considerable expertise to the topic of Precocious and Delayed Puberty Revisited. Top experts provide practical discussions of physical evidence of early or late pubertal development, offering a reasonable approach to patients presenting with these chief complaints.

  • Focal Neuropathies

    • 1 Edición
    • Volumen 201
    • Inglés
    Facial Neuropathies, Volume 202 summarizes research and treatment on focal neuropathies to update clinicians on nerve biology and new diagnostic techniques to guide investigation and treatment of mononeuropathies. The book explores research broadly applicable to all types of mononeuropathies as well as individual mononeuropathy syndromes. Chapters on individual mononeuropathies include anatomy, causes, controversial diagnoses, and current or potential future treatments.

  • The Microbiome and Neurotoxicity

    • 1 Edición
    • Volumen 11
    • Inglés
    Advances in Neurotoxicology, Volume 11 presents interesting chapters written by an international board of authors. Chapters in this new release include Gut microbiota as a mediator on the neurotoxicity of mercury, Relationships between lead-induced learning and memory impairments and gut microbiota disturbance in mice, Utility of zebrafish-based models in understanding molecular mechanisms of neurotoxicity mediated by the gut-brain axis, Alterations of gut microbiota linking environmental exposures to neurotoxicity, Iron Toxicity, Ferroptosis and Microbiota in Parkinson’s Disease: Implications for Novel Targets, and Modulation of gut microbiota with probiotics as a strategy to counteract endogenous and exogenous neurotoxicity.

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