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Elsevier

Libros en Ciencias de la Vida

  • Radiomics and Radiogenomics in Neuro-Oncology

    An Artificial Intelligence Paradigm - Volume 1: Radiogenomics Flow Using Artificial Intelligence
    • 1 Edición
    • Sanjay Saxena + 1 más
    • Inglés
    Radiomics and Radiogenomics in Neuro-Oncology: An Artificial Intelligence Paradigm, Volume One: Radiogenomics Flow Using Artificial Intelligence broadly encompasses the study of life-threatening brain and spinal cord malignancies, including primary lesions and those metastasizing to the central nervous system. Radiomics is an approach to medical imaging used to extract many quantitative imaging features using different data characterization algorithms, while radiogenomics, which has recently emerged as a novel mechanism in neuro-oncology research, focuses on the relationship of imaging phenotype and genetics of cancer. Sections in this book discuss several AI approaches that have been applied to conventional and advanced medical imaging data. These AI-based R-n-R tools have the potential to stratify patients into more precise initial diagnostic and therapeutic pathways and permit better dynamic treatment monitoring in this period of personalized medicine. While extremely promising, the clinical acceptance of R-n-R methods and approaches will primarily hinge on their resilience to non-standardization across imaging protocols and their capability to show reproducibility.

  • The neurobiology of Alcohol Use Disorder

    Neuronal mechanisms, current treatments and novel developments
    • 1 Edición
    • Volumen 175
    • Inglés
    The Mechanisms Behind Developing Dependence, Sub-groups, and Novel Approaches to Treatment, Volume 174 in the Neurobiology of Alcohol Abuse series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Substitution therapy in alcohol treatment, with a focus on mechanisms and possibilities, Designing and analyzing studies on treatments for alcohol dependence, The harm reduction approach for treatment of alcohol dependence, Current treatments for alcohol dependence, with a suggested focus on mechanisms and possibilities, Metabolomics in relation to alcohol dependence with focus on possibilities for precision medicine, and Repurposing drugs for treatment of alcohol dependence.

  • Heart Development and Disease

    • 1 Edición
    • Volumen 156
    • Inglés
    Heart Development and Disease, Volume 156 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters including Macrophages during heart valve development, Computational models of cardiovascular biology, Mechanisms of early sarcomere assembly, Role of RNA binding proteins during heart development and disease, Early heart development and morphogenesis, PSC models for development and disease, ECM or SHF development, Role of metabolism during heart development, Cellular ploidy in cardiac biology, and Genetics of CHD in the human population.

  • From Brain Dynamics to the Mind

    Spatiotemporal Neuroscience
    • 1 Edición
    • Georg Northoff
    • Inglés
    From Brain Dynamics to the Mind: Spatiotemporal Neuroscience explores how the self and consciousness is related to neural events. Sections in the book cover existing models used to describe the mind/brain problem, recent research on brain mechanisms and processes and what they tell us about the self, consciousness and psychiatric disorders. The book presents a spatiotemporal approach to understanding the brain and the implications for artificial intelligence, novel therapies for psychiatric disorders, and for ethical, societal and philosophical issues. Pulling concepts from neuroscience, psychology and philosophy, the book presents a modern and complete look at what we know, what we can surmise, and what we may never know about the distinction between brain and mind.

  • Molecular Impacts of Nanoparticles on Plants and Algae

    • 1 Edición
    • Huseyin Tombuloglu + 4 más
    • Inglés
    Molecular Impacts of Nanoparticles on Plants and Algae covers molecular mechanisms of plants/algae related to cellular uptake, translocation of nanoparticles, and genome, transcriptome, proteome, and metabolome responses against it. The book introduces readers to state-of-the-art developments and trends of nanoparticles and plants/algae including interactions of nanoparticles with biological compounds in vitro. Nanoscience and nanotechnology have rapidly been developed in the last few decades, and they have a wide range of applications in industry, medicine, food, and agriculture. In agriculture, nanoparticles (NPs) have successfully been used for growth regulation, crop protection and improvement. This book presents the most recent findings on nanoparticle and plant/algae interaction by focusing on molecular response mechanisms at genome, transcriptome, proteome and metabolome levels. In addition, uptake and translocation mechanism of nanoparticles are assessed both in plant and algae. Throughout this book, the latest developments and discoveries are highlighted, along with open problems and future challenges in molecular mechanisms of plants/algae as a response of nanoparticles.

  • Emerging Contaminants

    Sustainable Agriculture and the Environment
    • 1 Edición
    • Arpna Kumari + 4 más
    • Inglés
    Emerging Contaminants: Sustainable Agriculture and the Environment provides a thorough, comprehensive, and interdisciplinary overview of the many categories of emerging pollutants, including pharmaceuticals, insecticides, personal care items, and industrial chemicals, that are currently impacting the environment. With insights into the exposure associated consequences on crops and edible plants, this book is designed to enable foundational understanding as the basis for future research, as well as providing practical application guidance in current environments.Water resource shortages, declining arable land, environmental contamination with different exiting or ECs, shortcomings in the procedures for protecting cultivated land, and inefficiencies in the management of land tenure rights continue to pose challenges for agricultural sustainable development around the world. This book focuses on the impacts of ECs on sustainable agricultural production and explores possible response approaches.Following an introduction to environmental contaminants, this book discusses their fate in soils, presents the most up-to-date analytical methods for detecting them in different environmental matrices, and addresses current regulatory restrictions. Finally, this book ends with a chapter dedicated to conclusions and future perspectives.Emergin... Contaminants is an ideal resource for researchers and professionals from a variety of sciences including agricultural, plant, and environmental.

  • Microbial Technology for Agro-Ecosystems

    Crop Productivity, Sustainability, and Biofortification
    • 1 Edición
    • Vivek Kumar + 1 más
    • Inglés
    Microbial Technology for Agro-Ecosystems: Crop Productivity, Sustainability, and Biofortification describes the application of competent microbes in plant growth promotion, nutrient management and recycling from molecular perspectives. Understanding of molecular mechanism of Microbial diversity in association with plant roots is very imperative for plant health and ecosystem equilibrium.

  • Public Health and Toxicology Issues in Drug Research, Volume 2

    Toxicity and Toxicodynamics
    • 1 Edición
    • Rakesh K. Tekade
    • Inglés
    Public Health and Toxicology Issues in Drug Research: Toxicity and Toxicodynamics, Volume Two examines implications on public health and the impact of pharmaceuticals, chemical and food toxicants, dietary phytochemicals, and medical treatments. The book cover topics on pharmacokinetics and toxicokinetics, such as population pharmacokinetics/tox... the design of toxicokinetic studies, and the use of toxicokinetic data in preclinical safety assessments. In addition, it investigates the health effect caused by the bioaccumulation of pharmaceutical and personal care products and the impact of drug-induced toxicity on different systems of the body.Final sections discuss the mechanistic pathways of food toxicants and illustrate the molecular mechanisms of the chemopreventive role of dietary phytochemicals. Ethical, legal, societal, and professional issues in toxicology round off coverage, making this a valuable resource for anyone interested in learning more about the health impact and public health issues related to the toxicity of pharmaceuticals, dietary supplements, personal care products, and medical treatments.

  • Advanced Vaccination Technologies for Infectious and Chronic Diseases

    A guide to Vaccinology
    • 1 Edición
    • Vasso Apostolopoulos + 2 más
    • Inglés
    Advanced Vaccination Technologies for Infectious and Chronic Diseases is a comprehensive guide that delves into the intricate details of vaccine design, development across various platforms, and the path to commercialization. This book provides an introductory overview of vaccines, covering various types, developmental methodologies, delivery systems, adjuvants, immunization, and measurement of vaccine efficacy. It also showcases examples of vaccine research efforts targeting infectious diseases, autoimmune disorders, and cancer. The book concludes by exploring cutting-edge advances in proteogenomics, immunopeptidomics, and future vaccine technologies.The primary objective of this book is to inform a broad scientific audience about the fundamental concepts underlying vaccine and immunology. Further, it serves as an invaluable reference for understanding the critical steps in the journey from discovery to regulatory processes for human clinical trials, addressing common misconceptions and presenting factual information about vaccinations. Advanced Vaccination Technologies for Infectious and Chronic Diseases is a requisite reference for occupational health professionals whose roles involve supervision of immunization programs such as those working within the National Health Service, some sectors of higher education, or the pharmaceutical industry. It also caters to those researchers engaged in vaccine development and all who want to learn the processes involved from laboratory research to final product.

  • Novel Formulations and Future Trends

    Recent and Future Trends in Pharmaceutics, Volume 3
    • 1 Edición
    • Amit Kumar Nayak + 1 más
    • Inglés
    Novel Formulations and Future Trends, Volume Three in the Recent and Future Trends in Pharmaceutics series, explores aspects of pharmaceutics with an original approach focused on technology, novelties and future trends. It discusses the most important developments in drug delivery, including important and exciting areas such as mucosal, implantable, transdermal, gastroretentive, vaccine and targeted drug delivery systems. The field of pharmaceutics is highly dynamic and rapidly expanding day-by-day so it demands a variety of amplified efforts for designing and developing pharmaceutical processes and formulation strategies. This is an essential reference for researchers in academia and industry as well as advanced graduate students.New technologies are also explored including 3D printing and computational pharmaceutics.

  • Microbial Diversity in the Genomic Era

    Functional Diversity and Community Analysis
    • 2 Edición
    • Surajit Das + 1 más
    • Inglés
    Microbial Diversity in the Genomic Era: Functional Diversity and Community Analysis, Second Edition presents techniques used for microbial taxonomy and phylogeny, along with their applications and respective strengths and challenges. The book incorporates recently developed biosystematics methods and approaches to assess microbial taxonomy, with suitable recommendations for where to apply them across the range of bacterial identification and infectious disease research. Sections provide a broad overview of microbial genomics research and microbiome directed medicine and update on molecular tools for microbial diversity research, extremophilic microbial diversity, functional microbial diversity across application areas, microbial diversity and infectious disease research, and future directions. Step-by-step methodologies are provided for key techniques, along with applied case studies that break down recent research studies into practical components, thus illuminating pathways for new studies across the field.

  • Computational Intelligence in Protein-Ligand Interaction Analysis

    • 1 Edición
    • Bing Wang + 2 más
    • Inglés
    Computational Intelligence in Protein-Ligand Interaction Analysis presents computational techniques for predicting protein-ligand interactions, recognizing protein interaction sites, and identifying protein drug targets. The book emphasizes novel approaches to protein-ligand interactions, including machine learning and deep learning, presenting a state-of-the-art suite of skills for researchers. The volume represents a resource for scientists, detailing the fundamentals of computational methods, showing how to use computational algorithms to study protein interaction data, and giving scientific explanations for biological data through computational intelligence. Fourteen chapters offer a comprehensive guide to protein interaction data and computational intelligence methods for protein-ligand interactions.

  • Anoxygenic Phototrophic Bacteria

    • 1 Edición
    • Keizo Shimada + 1 más
    • Inglés
    Anoxygenic Phototrophic Bacteria is a comprehensive overview of phototrophic bacteriacovering the following: overview of photosynthesis and phototrophic bacteria; systematicsand characteristics of each taxon; ecology and cultivation; photosynthetic electrontransfer systems; metabolism; pigments and lipids; light-harvesting systems and reactioncenters; photosynthetic genes and regulation of gene expression; origin and evolution ofphotosynthesis; and the utilization of phototrophic bacteria.Chapters are written by some of Japan’s leading researchers in the area, providing researchersin photosynthesis, bacterial physiology, microbial ecology, artificial photosynthesis,bioph... biochemistry, industrial chemistry a highly detailed, up-to-date and thoroughlycross-refe... book in this interdisciplinary area. With very few books being published overthe last 25 years on the topic, this book especially fills a crucial need for young researchersand those working at the margins of interdisciplinary fields.

  • Open Electronic Data Capture Tools for Medical and Biomedical Research and Medical Allied Professionals

    • 1 Edición
    • Ashish Pundhir + 2 más
    • Inglés
    Open Electronic Data Capture Tools for Medical and Biomedical Research and Medical Allied Professionals explains the step-by-step of collecting and treating research data in a didactic manner. The book discusses four freely available data capture tools whose common feature is data collection and entry being done simultaneously rather than separately, thus saving resources and minimizing potential errors. It highlights the comparative features of each data capture tool, helping readers to understand the advantage and disadvantage of each one to decide which tool can be used to fulfill their needs.This is a valuable resource for researchers, students, and members of the biomedical and medical fields who need to learn more about data mining and management to improve the quality of their research work.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 119
    • Inglés
    Advances in Clinical Chemistry, Volume 119, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. Topics covered in this new release include Advances in Endotoxin Analysis, SARS-CoV-2 detection and surveillance, Osteopontin in Cancer, Gastrointestinal Hormones: History, Biology, and Measurement, Natriuretic Peptide Testing Strategies in Heart Failure: a 2023 Update, and Defining Allowable Total Error Limits in the Clinical Laboratory.

  • Functionalized Nanomaterials for Cancer Research

    Applications in Treatments, Tools and Devices
    • 1 Edición
    • Hamed Barabadi + 2 más
    • Inglés
    Functionalized Nanomaterials for Cancer Research: Applications in Treatments, Tools and Devices presents an in-depth and step-by-step description of knowledge on functionalized nanomaterials for cancer research, including treatment and future developments as well as their impact on patients’ overall outcomes. The book discusses functionalized nanoplatforms for cancer detection and imaging, interactions between nanomaterials and cancer cells, and drug resistant malignancies. The book's chapters are organized in a manner that can be readily adopted as sources for new and further studies by highlighting the main in vitro and in vivo nano-therapeutic achievements on cancer. Additionally, current trends on functionalized nanomaterials for cancer research and commercial scale opportunities are discussed. This is a valuable resource for researchers, oncologists, students, and members of the biomedical and medical fields who want to learn more about the potential of nanotechnology in cancer research and treatment.

  • Chronic Complications of Diabetes Mellitus

    Current Outlook and Novel Pathophysiological Insights
    • 1 Edición
    • Didac Mauricio + 1 más
    • Inglés
    Chronic Complications of Diabetes Mellitus: Current Outlook and Novel Pathophysiological Insights provides a holistic view of the disease, discussing not only its classical complications but also the under recognized and managed conditions associated with diabetes. Chapters also discuss advances in our understanding of the genomic architecture of diabetes complications and how precision medicine can be used to personalize their management. Endocrinologists, diabetologists, primary care physicians and researchers interested in complications of diabetes mellitus and cutting-edge information will find this to be a comprehensive tome on the topic. Diabetes complications include pathological changes usually related to the vascular system and classical target organs. However, there are also nonclassical complications independent or partially independent from vascular damage that are often overlooked.

  • G4 biology

    • 1 Edición
    • Volumen 695
    • Inglés
    G4 Biology, Volume 695 in the Methods in Enzymology series, highlights high value topics such as Assays to measure G4 resolution by DNA helicases, In gel staining methods of G4 DNA and RNA structures, Methods to probe the folding pathways of four-stranded intercalated cytosine-rich motifs at single base-pair resolution, Analyzing the effect of transcription coupled R-loop formation on G4 formation, Integrated Structural Biology for the study of higher-order G4 structures, Advancing the Study of Protein-G4 Interactions in DNA Repair: Insights from Biolayer Interferometry and Circular Dichroism Spectroscopy, Immunofluorescence microscopy (IF) of G-quadruplex and R-loops, and more.Additional chapters delve into Production of the anti-G-quadruplex antibody BG4 for efficient ChIP-seq and CUT&Tag analysis: from plasmid quality control to validation, Utility of intercalator displacement assays for screening of ligands for i-motif DNA structures, Potentiometric titrations to study ligand interactions with DNA i-motifs, Towards Profiling of the G-Quadruplex Targeting Drugs in the Living Human Cells Using NMR Spectroscopy, and Identification of bona fide G4-binding proteins, Observing Pif1 opening dsDNA and G4 in real time by manipulation under magnetic tweezers, and in vivo detection of DNA secondary structures using Permanganate/S1 Footprinting with direct adapter ligation and sequencing (PDAL-Seq).

  • Improving and Tailoring Enzymes for Food Quality and Functionality

    • 2 Edición
    • Rickey Y. Yada + 1 más
    • Inglés
    Improving and Tailoring Enzymes for Food Quality and Functionality, Second Edition covers the most relevant information demanded in the production, engineering, and application of enzymes. The title is very detailed and an important cross-discipline resource that merges academia and industry. This totally revised new edition covers a broad range of topics related to enzymes and their use in food, presenting both the fundamental theory and practical application, updated with interesting novel information on biosensors, waste, valorization, up-cycling and engineering perspectives, besides an increased focus on sustainability.

  • Replacement Therapies in Adrenal Insufficiency

    • 1 Edición
    • Peter C. Hindmarsh + 1 más
    • Inglés
    Replacement Therapies in Adrenal Insufficiency provides a thorough understanding of the conditions which result in adrenal insufficiency. Never before has one source of information combined all updates on current causes and mechanisms of adrenal sufficiency to allow for quick reference and subsequent treatment decisions. Scientific data on this broad condition includes specific disease coverage of Addison’s disease, hypopituitarism, congenital adrenal hypoplasia and adrenalectomy. Practical points in diagnosis, dosing, drug interactions, replacement therapies and emergency situations are also provided as guidance for overall management.

  • Sweetened Concentrated Milk Products

    Science, Technology, and Engineering
    • 1 Edición
    • Juan Sebastián Ramírez-Navas
    • Inglés
    Sweetened Concentrated Milk Products: Science, Technology, and Engineering provides the most updated and comprehensive knowledge on different SCM products, delving into the production processes for each. Written by international experts, this book discusses existing information on concentrated milk and its more commercial forms, including evaporated and condensed milks. Other products detailed in this text include dulce de leches, such as sweetened caramelized goat’s milk, panelitas de leche (milk panels), and various milk-based delicacies. The book presents the definition, main characteristics, common defects, and elaboration process for each commercial form. In addition, the book includes lifetime calculation data and results of the addition of whey into milk candies. Lastly, it provides information on the quality parameters which all SCMs must meet, including experimental design and application examples in SCM research and development. This is a vital resource for researchers and practitioners in dairy science with interests and work in SCM product formulation, technology, and seeking solutions for their defects.

  • Functional Foods and Chronic Disease

    Role of Sensory, Chemistry and Nutrition
    • 1 Edición
    • Michel Aliani + 1 más
    • Inglés
    Functional Foods and Chronic Disease: Role of Sensory, Chemistry and Nutrition explores the range of functional foods that are effective against a wide range of chronic diseases and addresses the impact of functional food bioactive compounds on organoleptic properties. Beginning with an introduction that details the key sensory and advanced instrumental methods essential for addressing the common problems associated with designing functional foods, the book also addresses the impact of aging and chronic diseases on sensory acuity as well as the effectiveness of functional foods in treating a wide range of chronic diseases. Sections highlight the need for acceptable functional foods for individuals suffering from a wide range of chronic diseases and contain practical recommendations for their development. Food scientists, nutritionists, dietitians, food product developers, food supplement producers, food ingredient developers, natural product scientists, herbalists, and pharmacists, as well as students studying related areas, will benefit from this important resource.

  • Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds

    From Laboratory to Industry
    • 1 Edición
    • Yongjun Wei + 2 más
    • Inglés
    Many plant-derived bioactive compounds are the foundation for drugs or effective drugs to cure diseases. Usually, the bioactive compounds in plant biomass are low, and the extraction of bioactive compounds from plants is not eco-friendly, which limits their application in drugs and other industries. While the biosynthesis of some complex bioactive compounds is possible, the scale-up and chemical process technology still needs further application in commercial production of the plant-derived bioactive compounds.Scale-up and Chemical Process for Microbial Production of Plant-Derived Bioactive Compounds: From Laboratory to Industry summarizes recent commercial microbial production strategies for plant-derived bioactive compounds. This comprehensive summary will be of great interest to scientists and researchers, as well as engineers who work on the microbial production of plant-derived bioactive compounds in the industry.

  • Enhancement of Brain Functions Prompted by Physical Activity Vol 1

    • 1 Edición
    • Volumen 283
    • Inglés
    The goal for this special edition of Progress in Brain Research extends beyond merely probing the yet-to-be-uncovered links between physical exercise and cognitive improvement. We aim to advance our knowledge, pushing the envelope of what is currently understood. We are particularly focused on how purposefully structured physical activities, carefully chosen participant groups, and specific cognitive areas can optimize the cognitive and mental health benefits derived from physical exercise. The inaugural volume of this series introduces 3 review articles and 7 original pieces of research, encompassing both behavioral experiments and neuroimaging studies. Our focus is on experimental research that sheds light on the immediate and long-term impact of physical exercise on cognition as well as expert opinions and systematic reviews that compile current findings and suggest avenues for upcoming research.

  • CRISPRized Horticulture Crops

    Genome Modified Plants and Microbes in Food and Agriculture
    • 1 Edición
    • Kamel A. Abd-Elsalam + 2 más
    • Inglés
    CRISPRized Horticultural Crops: Genome Modified Plants and Microbes in Food and Agriculture summarizes applications of CRISPR/Cas systems and its advanced variants e.g., CRISPR/Cpf1, base editing and prime editing, for precise editing of horticultural crops. The book discusses vector transformations methods, epi-genome, deep learning, synthetic biology, and precision breeding for improving yield and quality related attributes in horticultural crops. With coverage of the relevant technologies and their applications, the book also includes bioinformatics and large-scale databases and their potential application in fruits, vegetables and ornamental plants and sections on regulatory concerns related to CRISPR edited crops. Horticultural crops, including fruit, vegetable and ornamental plants are an important component of agriculture production systems and play an important role in sustaining human life.

  • Polymeric Membrane Formation by Phase Inversion

    • 1 Edición
    • Naser Tavajohi + 1 más
    • Inglés
    Polymeric Membrane Formation by Phase Inversion analyzes the four main phase inversion techniques. Effective parameters in each technique are covered, along with the methodologies needed to prepare advanced membranes for specific separations in both liquid and gas phases. Roll-to-roll casting, spinning hollow fiber, and electrospinning nanofibers are presented, along with an analysis of the impact of solvent toxicity, membrane production, and the source of raw materials on the environment. The book describes a roadmap for designing different morphological characteristics for preparing specific membranes for special applications, along with the merits and disadvantages of each method. This book provides an easy, comprehensive reference for academic and industry professionals working in membrane engineering.

  • Beneficial Microbes for Sustainable Agriculture under Stress Conditions

    Functional Traits and Regulation
    • 1 Edición
    • Tongmin Sa
    • Inglés
    Beneficial Microbes for Sustainable Agriculture under Abiotic Stress: Functional Traits and Regulation highlights the potential for microbe-mediated stress phytotolerance to be improved by presenting multiple scenarios of application and results.In most research and studies, abiotic stress is applied singularly to specific plants inoculated with a bioinoculum or a microbial consortium to isolate specific plant-microbe responses. However, in reality, plants are continually exposed to a multitude of different stresses simultaneously occurring. This book presents microbial functional traits and microbe-mediated plant responses under both specific or combined stress conditions. Collectively, it provides insights into microbial functional traits and microbe-mediated plant responses in a wide range of conditions, providing foundational understanding of their potential benefits, and inspiring further research.The book also centers on specific microbial strains and groups which have been shown to effectively promote stress tolerance, and which could be utilized to boost agricultural production under stress conditions. Their potential utilization in stress affected lands not just improves crop production but could also be in line with sustainable agriculture.With the advancement of tools such as omics related technologies, emerging information on microbial functional traits and regulations on microbe-mediated phytotolerance will also allow us to develop relevant biotechnologies harnessing potentials of plant-microbe interactions under stress conditions. The information in this volume will be of interest to those working toward these next steps.

  • Encyclopedia of Fish Physiology

    • 2 Edición
    • Sarah L. Alderman + 1 más
    • Inglés
    Encyclopedia of Fish Physiology, Second Edition is a comprehensive, introductory-level reference work that aims to unite readers in the wonders of this discipline. Chapters highlight where physiological systems and processes are conserved across vertebrate groups, which supports the use of fish as a vertebrate model for investigating fundamental problems in physiology and knowledge transfer to the medical field. Other chapters highlight unique specializations and adaptations that allow fish to survive in challenging environments, leading to a deeper appreciation of the natural world. Final sections demonstrate the consequences of perturbing physiological systems and how this knowledge can empower conservation strategies to protect fish. Much has changed in the field of fish physiology since publication of the previous, Prose award winning, edition. For example, we understand better the impacts of global climate change on the physiological systems of fish, and we have gained a deeper mechanistic understanding of physiological processes through technological advancements such as gene editing with CRISPR, whole genome sequencing, and quantitative ‘omic` approaches. The new edition greatly expands the closing thematic section focused on applying fish physiology to real world challenges with topics including ocean acidification, declining habitat quality due to human activities, and the use of zebrafish in biomedical studies on tissue regeneration, neurological disorders and cancer.

  • Myeloid-Derived Suppressor Cells

    • 1 Edición
    • Volumen 184
    • Inglés
    Myeloid-Derived Suppressor Cells, Volume 184 in the Methods in Cell Biology series includes comprehensive protocols to assess the role of myeloid-derived suppressor cells (MDSCs), an immature, heterogenous cell population from the myeloid lineage with a potent immunosuppressive activity in a variety of diseases. This volume includes interesting protocols that address the Detection of myeloid-derived suppressor cells by flow cytometry, Determination of murine myeloid-derived suppressor cells by flow cytometry, Isolation of Myeloid-Derived Suppressor Cells (MDSC) from Endometriotic Mice Model and their Immunomodulatory Functions, Simple protocol for measuring CD11b+ GR-1+ (Ly6C+/Ly6G+) myeloid cells from a minimum volume of mouse peripheral blood, and much more.Additional chapters cover Assessment of myeloid-derived suppressor cell differentiation ex vivo, Single clonal tracking on biomimetic microtextured platforms for real-time guided migration analysis of myeloid-derived suppressor cell dissemination characteristics ex vivo, Isolation and immunosuppressive functions of myeloid-derived suppressor cell-derived exosomes, Characterization of lysosomal acid lipase in Ly6G+ and CD11c+ myeloid-derived suppressor cells, In Vitro Osteoclastogenesis Assessment using Murine Myeloid-derived Suppressor Cells, Estimating Nitric Oxide (NO) from MDSCs by Griess Method, and In vitro generation of myeloid-derived suppressor cells (MDSCs) from hematopoietic progenitor cells (HPCs).

  • Modern Inference Based on Health-Related Markers

    Biomarkers and Statistical Decision Making
    • 1 Edición
    • Albert Vexler + 2 más
    • Inglés
    Modern Inference Based on Health Related Markers: Biomarkers and Statistical Decision Making provides a compendium of biomarkers based methodologies for respective health related fields and health related marker-specific biostatistical techniques. The book introduces correct and efficient testing mechanisms, including procedures based on bootstrap and permutation methods with the aim of making these techniques assessable to practical researchers. In the biostatistical aspect, it describes how to correctly state testing problems, but it also includes novel results, which have appeared in current statistical publications.In addition, the book discusses also modern applied statistical developments that consider data-driven techniques, including empirical likelihood methods and other simple and efficient methods to derive statistical tools for use in health related studies.

  • Marine Bivalve Mollusks and Emerging Pollutants

    • 1 Edición
    • Guangxu Liu
    • Inglés
    Marine Bivalve Mollusks and Emerging Pollutants: Toxicological Impacts provides the most updated and comprehensive knowledge of the toxicological impacts of a variety of emerging pollutants on marine bivalve mollusk species. In addition to synthesizing recent toxicological findings, the book also discusses toxification mechanisms, current challenges, and future research prospects. Written by international experts, this book assesses new advances in the toxicological impacts of pollutants, including microplastics, bromide flame retardants, nanomaterials, pharmaceutical residues, personal care products, pesticides, and perfluorinated compounds. In addition, it details how these can affect reproduction, embryonic development, metabolism, and immune systems of marine bivalves. Behavioral responses and neuroendocrine regulation is also discussed. Toxification mechanisms are interpreted at both physiological and molecular levels. The book concludes with current research and environmental challenges and potentials for further, future study techniques.

  • Biostimulants in Plant Protection and Performance

    • 1 Edición
    • Azamal Husen
    • Inglés
    Biostimulants in Plant Protection and Performance provides the latest research on biostimulants, a diverse class of compounds that includes substances or microorganisms that are helpful in sustainable plant growth and development. These substances accelerate plant growth, yield, and chemical composition even under unfavorable conditions, and include nitrogen-containing compounds, humic materials, some specific compounds released by microbes, plants, and animals, various seaweed extracts, bio-based nanomaterials, phosphite, silicon, and more. Additionally, the book discusses new generation products and bioproducts that are being developed for sustainable plant growth and protection, including research updates in biotechnology, nanobiotechnology, and the protective role of biostimulants. As the use of new generation biostimulants can enhance plant production systems through a significant reduction of synthetic chemicals, such as pesticides and fertilizers, and even elicit plant tolerance to various climate change-related stresses, this book is a welcomed edition to many fields of study.

  • Inmunología básica

    Funciones y trastornos del sistema inmunitario
    • 7 Edición
    • Abul K. Abbas + 2 más
    • Español
    Nueva edición del texto derivado de la obra de referencia en Inmunología, "Abbas, Inmunología molecular y celular" en el que se presenta de una forma concisa y visual el nivel de información adecuado para el estudiante que se enfrenta por primera vez a la asignatura. Destaca su gran riqueza y calidad iconográfica. La inclusión de tablas, esquemas, puntos clave en negrita y preguntas de autoevaluación. En cuanto a las principales novedades cabe destacar la inclusión de contenidos nuevos y ampliados sobre pandemias, COVID-19 e inmunidad de rebaño, resistencia y susceptibilidad a COVID-19, vacunas de ARN y vacunas híbridas, inmunoterapia tumoral, respuestas inmunitarias innatas a los virus, mecanismos de tolerancia inmunológica e inmunoterapia para enfermedades autoinmunes, alérgicas y otras enfermedades inflamatorias y el cáncer. La nueva edición ofrece acceso a material adicional online en inglés a través de e-book+

  • Diabetes. Secretos

    • 1 Edición
    • Michael T. McDermott + 1 más
    • Español
    Nuevo título enmarcado dentro de la serie “Secretos” que, al igual que otros títulos de la misma serie, presenta el popular formato de preguntas y respuestas, incluyendo también listas, tablas, perlas, ayudas para la memoria y un estilo fácil de leer, lo que hace que la consulta, la referencia y la revisión sean rápidas, fáciles y agradables. Este nuevo título contiene todas las preguntas que el lector podría llegar a plantearse sobre cualquiera de los temas relacionados con la Diabetes. Además, el manejable tamaño y la lista de los 100 Secretos Top en Diabetes ayudan al lector a conocer de primera mano los retos a los que debería afrontarse día a día. Cobertura actualizada de la gama completa de temas relacionados con la diabetes, incluida la diabetes durante el embarazo; control de la diabetes en pacientes con cáncer; control de la diabetes durante el ejercicio, los deportes y la competición; control de la diabetes en pacientes hospitalizados, y más. La obra ofrece acceso al contenido del e-book en inglés a través de la plataforma de e-book+

  • Diagnosis and Treatment of Osteoporosis

    A Case-Based Approach
    • 1 Edición
    • Ronald C. Hamdy
    • Inglés
    **Selected for Doody’s Core Titles® 2024 in Endocrinology/Metabo... Disease**Diagnosis and Treatment of Osteoporosis: A Case-Based Approach is a practical guide that will be useful to a wide range of practicing and in-training clinicians, including physicians, nurse practitioners and physician assistants. With its clinical case and scenario-based approach, readers can quickly decide which clinical problem to address such as the management of osteoporosis of a particular clinical problem (Atypical femoral shaft fractures, Glucocorticoids and bone health, etc.). Each chapter is self-contained with a list of objectives at the beginning and a presentation of clinical cases that encourages self-learning to non-specialized clinical staff. This book is easily accessible to non-specialists, allowing any healthcare provider to learn how to diagnose and manage osteoporosis in the context of their practice.

  • Paraneoplastic Neurologic Disorders

    • 1 Edición
    • Volumen 200
    • Inglés
    Paraneoplastic Neurological Disorders, Volume 200 covers new, recent descriptions of autoantibodies against neuronal cell surface antigens (only partly associated with paraneoplastic disorders) and the introduction of new immuno-oncological drugs that can contribute to diseases that are pathogenetically indistinguishable from paraneoplastic syndromes. Besides investigating the pathogenetic mechanisms of these disorders, this book also explores what the introduction of new drugs used in immune checkpoint inhibitor cancer therapy are teaching us in terms of immunopathogenesis. Following sections present individual syndromes (phenotypical clinical manifestations) of the CNS, PNS, NMJ, and muscle.Finally, the book investigates the role of antibody markers that differentiate by cytoplasmic, nuclear, and neuronal cell surface reactivities. Side effects of the new immuno-oncological drugs increasingly used in cancer therapy are also covered.

  • Biochemical Immunology of Diabetes and Associated Complications

    • 1 Edición
    • Pratima Tripathi + 2 más
    • Inglés
    Biochemical Immunology of Diabetes and Associated Complications offers in-depth coverage of the association of biochemical and immunological aspects of the human body in diabetes. It discusses the suppression and modulation of the immune system and the impact of immunochemicals on the biochemical pathways in diabetes, along with associated complications. The book enumerates the exigency in knowledge about the immunomodulators as therapeutic targets to cure the syndrome. It will serve as an important reference for medical practitioners, researchers, medical students, masters and doctoral students. In addition, it could also be used as a reference for science graduates, science teachers, and researchers.

  • Magnetic Tweezers for the Study of Protein Structure and Function

    • 1 Edición
    • Volumen 694
    • Inglés
    Magnetic Tweezers for the Study of Protein Structure and Function, Volume 694 in the Methods in Enzymology serial highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Single membrane protein tethering for magnetic tweezer experiments, Membrane protein folding studies using a robust magnetic tweezer method, Magnetic tweezers in cell mechanics, and more.

  • Biosensors for Foodborne Pathogen Detection

    A Rapid Detection Approach
    • 1 Edición
    • Manoj Kumar Pal + 2 más
    • Inglés
    Biosensors for Foodborne Pathogens Detection: A Rapid Detection Approach covers rapid and accurate measurement for biosensing analysis. This book is organized in a systematic way, covering basic introduction and advanced approaches in biosensing and their use in the detection of food pathogens. This compilation includes chapters such as Methods, techniques and latest developments in the detection of foodborne pathogens; Basic principles in Biosensors and bioelectronics for the foodborne pathogens; Various bio-recognition receptors used in the biosensors; Nanomaterials and signal amplification in biosensors for foodborne pathogens; electrochemical biosensors for foodborne pathogens; Optical biosensors for foodborne pathogens, and more. This book act as a comprehensive resource for researchers or scientists working in food safety, especially in microbial food spoilage detection using biosensors.

  • Handbook of Goldenberry (Physalis peruviana)

    Cultivation, Processing, Chemistry, and Functionality
    • 1 Edición
    • Mohamed Fawzy Ramadan
    • Inglés
    Handbook of Goldenberry (Physalis peruviana): Cultivation, Processing, Chemistry, and Functionality presents multidisciplinary coverage of P. peruviana and its role as in food, cosmetic, and pharmaceutical products. Broken into three sections, the book addresses the cultivation, species, and cultivars of Physalis peruviana, along with its chemistry, functionality, health-promoting properties, technologies, processing, and applications. Written for nutrition researchers, food scientists, food chemists, food technologists, nutritionists, and those studying related field, this book is a timely reference for those who wish to learn more about this functional food.

  • Nanotechnology for Abiotic Stress Tolerance and Management in Crop Plants

    • 1 Edición
    • Ramesh Namdeo Pudake + 2 más
    • Inglés
    Nanotechnology for Abiotic Stress Tolerance and Management in Crop Plants reviews the most recent literature on the role of nanomaterials in achieving sustainability in crop production in stressful environments. The book explores the adverse conditions caused by abiotic stress to crop plants and the methods by which these conditions can be potentially overcome through developments in nanoscience and nanotechnology. Abiotic stresses such as drought, salinity, temperature stress, excessive water, heavy metal stress, and UV stress are major factors which may adversely affect the growth, development, and yield of crops.While recent research for ways of overcoming the physiological and biochemical changes brought on by these stresses has focused on genetic engineering of plants, additional research continues into alternative strategies to develop stress tolerant crops, including the use of nanoscience and nanotechnology.

  • Microbes at Bio/Nano Interfaces

    • 1 Edición
    • Volumen 54
    • Inglés
    Microbes at Bio/Nano Interfaces, Volume 54 in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Advanced Hydrogel for Management of Bacterial Wound Infections, Biofilm Characterization: Imaging, analysis and considerations, Parasitic worm interactions with host molecular machinery, Investigation of microbes and surface carbohydrates using Atomic Force Microscopy, Interactions Between Microbial Cells and Titanium Implant Surfaces, Targeting Bacterial Polysaccharides with Antibodies and Vaccines, and much more.Other sections cover Using next generation sequencing to study host-pathogen interactions, Microbial Nano-Biosynthesis: Biomedical, Food and Environmental Applications, and Functional co-expression of LEA peptides: Providing an environment for efficient cellular recombinant protein expression.

  • Artificial Intelligence in Medicine

    From Ethical, Social, and Legal Perspectives
    • 1 Edición
    • Joseph JY Sung + 1 más
    • Inglés
    Artificial Intelligence in Medicine: From Ethical, Social, and Legal Perspectives provides answers on how to improve acceptance and diminish the anxiety of the use of AI-assisted medicine. Through a series of social, ethical, and legal discussions from clinicians, social scientists, ethicists, and legal experts, this important reference has coverage that includes good data custodianship and stewardship, data access, data bias, data & healthcare equity, privacy and confidentiality, algorithmic understanding, and regulatory guidance, accountability, and legal responsibility.This reference will explain to healthcare providers how AI will enhance healthcare, will introduce to scientists and researchers the ethical and social aspect of AI that needs to be addressed, and will urge policymakers and health authorities to consider the legal framework needed to implement AI technology in healthcare.

  • Recent Developments in Nanomaterial-based Sensing of Human Pathogens

    • 1 Edición
    • Seshadri Reddy Ankireddy + 1 más
    • Inglés
    Recent Developments in Nanomaterial-based Sensing of Human Pathogens is a comprehensive book providing recent insights into nanomaterial-based sensing of human pathogens. The chapters cover diverse topics, including nanosensor analytical properties, the intersection of nanosensors and biological markers in pathogenic diseases, nanodevices in neurological infections, foodborne pathogen detection, viral and bacterial biomarkers, fungal disease diagnostics, mycoplasma-triggered inflammation, protozoan diseases, and mycoplasma clinical detection. This book serves as a valuable resource showcasing cutting-edge advancements in nanotechnology for pathogen detection, contributing to improved diagnosis and disease management across various domains.

  • Dynamic Aquaria

    Building and Restoring Ecosystems and the Biosphere
    • 4 Edición
    • Walter H. Adey
    • Inglés
    Dynamic Aquaria: Building and Restoring Ecosystems and the Biosphere, Fourth Edition demonstrates how the living systems modeling of aquatic ecosystems for ecological, biological, physiological research, and ecosystem restoration produce answers to very complex ecological questions. The book describes unique characteristics of water that have allowed carbon chemistry to flourish and evolve life over 4 billion years, along with current disruptions such as global warming, overfishing, and chemical pollution. New content in this edition includes the use of LED lighting, DNA sequencing in microcosm construction and analysis, and the expansion of the bioengineered tool Algal Turf Scrubbing (ATS) to combat global pollution problems.The book also features new information on marine calcification, research microcosms, thermogeography, and methods of water movement for minimizing plankton loss. It supports a deeper biological and ecological intelligence among the human population to better understand the processes behind environmental issues.

  • Gallstone Formation, Diagnosis, Treatment and Prevention

    • 1 Edición
    • Rajani Sharma + 2 más
    • Inglés
    Gallstone Formation, Diagnosis, Treatment, and Prevention describes the current scenario of gallstones and adopted treatment methods. It is a complete reference for researchers introducing new techniques to help prevent extreme treatments such as a cholecystectomy. This reference provides current knowledge and basic challenges of understanding gallstone formation, with all variations of composition, including complications of the treatment process. This content directs researchers to focus on gallstone mechanisms to design and develop new treatment methods. The book provides all possible factors for gallstone formation as well as preventative measures.

  • Applications of Artificial Intelligence in Healthcare and Biomedicine

    • 1 Edición
    • Abdulhamit Subasi
    • Inglés
    Applications of Artificial Intelligence in Healthcare and Biomedicine provides ​updated knowledge on the applications of artificial intelligence in medical image analysis. In 16 chapters, it presents artificial applications in Electrocardiogram (ECG), Electroencephalogram (EEG) and Electromyography (EMG), signal analysis, Computed Tomography (CT), Magnetic Resonance Imaging (MR), and Ultrasound image analysis. It equips researchers with tools for early breast cancer detection from mammograms using artificial intelligence (AI), AI models to detect lung cancer using histopathological image, and a deep learning-based approach to get a proper and faster diagnosis of the Optical Coherence Tomography (OCT) images.In addition, it presents 3D medical image analysis using 3D Convolutional Neural Networks (CNNs). Final sections cover an AI-based approach to forecast diabetes patients' hospital re-admissions. This is a valuable resource for clinicians, researchers, and healthcare professionals who are interested in learning more about the applications of Artificial Intelligence and its impact in medical/biomedical image analysis.

  • Retinal and Choroidal Vascular Diseases of the Eye

    • 1 Edición
    • Jay Chhablani
    • Inglés
    Retinal and Choroidal Vascular Diseases of the Eye explores a variety of retinal and choroidal vascular diseases, covering their pathogenesis, clinical features, and management strategies. The book begins with an outline of the basic features of retinal and choroidal vasculature before moving on to imaging techniques. Chapters then delve into specific diseases and abnormalities, as well as vascular diseases that are associated with systemic inflammatory diseases. The book then moves onto considering vascular diseases associated with system conditions before considering vascular tumors. Recent innovations and upcoming treatment options are also explored for the various diseases throughout the book.This comprehensive reference provides a deep dive into vascular diseases of the eye, and is a must-have reference for ophthalmologists, medical and surgical retina specialists, and researchers in related fields.

  • Microbial Essentialism

    An Industrial Prospective
    • 1 Edición
    • Raghvendra Pratap Singh + 4 más
    • Inglés
    Microbial Essentialism: An Industrial Prospective refers to properties specifically possessed by microbes, including the secretion of metabolites which make them unique. These microorganisms can be commercially exploited for beneficial purposes such as the production of whole microbial cells, for products for direct use, or as starting raw materials in the manufacture of other commercial products. The book reviews the newest techniques, approaches, and options in the use of microorganisms for the manufacture of industrially important products such as pharmaceuticals, industrial enzymes, chemicals, proteins, foods and beverages, and fuels. Additional sections cover fundamental principles of established and innovative industrial microbiology and biotechnology processes and products while also discussing industrial microorganisms and the technology required for large-scale cultivation and isolation of fermentation products.

  • Pharmacological Advances in Central Nervous System Stimulants

    • 1 Edición
    • Volumen 99
    • Inglés
    Pharmacological Advances in Central Nervous System Stimulants, Volume 99 in the Mechanisms, Therapeutic Uses, and Abuse of Stimulants series, showcases recent pharmacological progress investigating both therapeutic (ADHD, binge-eating and narcolepsy) and abuse aspects of a number of stimulants, some of which are long-standing (amphetamines, cocaine and nicotine) while others are emerging (cathinones). Specific chapters in this new release include Transgenerational Epigenetic Inheritance of Phenotypes Associated with Parental Exposure to Drugs of Abuse, Dysregulation Of Brain Cholesterol Homeostasis by Psychostimulants, Modeling Methamphetamine Use Disorder in Mammals: Sex Differences in Behavioral Consequences and Gene Expression, and much more.Additional sections focus on Second Generation Stimulants – Pharmacological and Clinical Advances in The Treatment of ADHD And Binge-eating disorder, Pharmacology Of Stimulant – Opioid Co-Use, Role Of Age and Sex in Determining the Risk For Adverse Consequences Following Exposure To Amphetamines, Modafinil, An Atypical CNS Stimulant, Modulators Of Nicotine Reward-Related and Reinforcement-Relate... Behaviors, Methamphetamine Effects on Peripheral Immune System, Post-Translational Mechanisms in Neurotransmitter Efflux, The Many Enigmas of Nicotine, Genetic Variation in The Neuregulin-Erbb Signaling Pathway And Substance Use Disorders, Pharmacology And Neurotoxicology of Synthetic Cathinones, and more.

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