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Elsevier

Libros en Ciencias de la Vida

  • Diagnostic Molecular Pathology

    A Guide to Applied Molecular Testing
    • 2 Edición
    • William B. Coleman + 1 más
    • Inglés
    Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing, Second Edition assembles a group of experts to discuss the molecular basis and mechanisms of major human diseases and disease processes and how the molecular features of disease can be harnessed to develop practical molecular tests for disease detection, diagnosis and prognosis. The book explains how molecular tests are utilized in the treatment of patients in personalized medicine, highlights new technologies and approaches of applied molecular pathology, and discusses how this discovery-based research yields new and useful biomarkers and tests. As it is essential to stay up-to-date on new molecular diagnostics in this changing field, this book covers critically important areas in the practice of personalized medicine and reflects our understanding of the pathology, pathogenesis and pathophysiology of human disease.

  • Molecular Pharmaceutics and Nano Drug Delivery

    Fundamentals and Challenges
    • 1 Edición
    • Umesh Gupta + 1 más
    • Inglés
    Molecular Pharmaceutics and Nano Drug Delivery: Fundamentals and Challenges provides a thorough resource for both beginners and established scientists, bringing fundamental knowledge about key challenges of these carriers down to the molecular level. The book satisfies the need of availability of literature at single platform with the detailed knowledge to understand crucial aspects, such as regulatory, clinical, toxicological and the formulation requirements of these carriers. This is a valuable resource for graduates, pharmaceutical researchers and anyone working on aspects of pharmaceutics, molecular pharmaceutics and nano-drug/gene delivery. So called ‘novel drug delivery systems’ are numerous, with each having different approaches to their production, characterization and evaluation. The proper understanding of these dosage forms, as well as their critical attributes such as toxicity and regulatory requirements are aspects which researchers should know before they begin working on these carriers. This book provides this critical information.

  • Advances in Physical Organic Chemistry

    • 1 Edición
    • Volumen 57
    • Inglés
    Advances in Physical Organic Chemistry, Volume 57 presents the latest reviews of recent work in physical organic chemistry, providing a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

  • Modern Methods of Drug Design and Development

    • 1 Edición
    • Volumen 690
    • Inglés
    Modern Methods of Drug Design and Development, a volume in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on a variety of topics, including Recombinant protein purification for structural and kinetic studies, Steady-state kinetic analysis of reversible enzyme inhibitors, Steady-State Enzyme Kinetics, Analysis of enzyme kinetic data using ICEKAT, NMR techniques in drug discovery, Dynamic simulations and pre-steady state kinetics to guide drug discovery, Design and assay of substrate-product analogues for racemases and epimerases, Sensitive high throughput methods to screen for P450 inhibition: A- MI complex forming drugs, and more. Other chapters cover Sensitive high throughput methods to screen for P450 inhibition: B-Heme loss causing drugs, Discovery and development of inhibitors of acetyltransferase Eis to combat Mycobacterium tuberculosis, Crystallographic fragment screening in academic cancer drug discovery, Fast fragment- and compound-screening pipeline at the Swiss Light Source, Chemical biology, enzymology and drug discovery, PROTACs, Proximity-Induced Pharmacology (PROTACs), and much more.

  • Pharmacognosy

    Fundamentals, Applications, and Strategies
    • 2 Edición
    • Simone Badal McCreath + 1 más
    • Inglés
    Pharmacognosy: Fundamentals, Applications and Strategies, Second Edition represents a comprehensive compilation of the philosophical, scientific and technological aspects of contemporary pharmacognosy. The book examines the impact of the advanced techniques of pharmacognosy on improving the quality, safety and effectiveness of traditional medicines, and how pharmacokinetics and pharmacodynamics have a crucial role to play in discerning the relationships of active metabolites to bioavailability and function at the active sites, as well as the metabolism of plant constituents. Structured in seven parts, the book covers the foundational aspects of Pharmacognosy, the chemistry of plant metabolites, their effects, other sources of metabolites, crude drugs from animals, basic animal anatomy and physiology, technological applications and biotechnology, and the current trends in research. New to this edition is a chapter on plant metabolites and SARS-Cov-2, extensive updates on existing chapters and the development of a Laboratory Guide to support instructors execute practical activities on the laboratory setting.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 116
    • Gregory S. Makowski
    • Inglés
    Advances in Clinical Chemistry, Volume 116, the latest release in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists.

  • Microbiome Drivers of Ecosystem Function

    • 1 Edición
    • Javid A. Parray + 2 más
    • Inglés
    Microbiome Drivers of Ecosystem Function, the latest release in the Microbiome Research in Plants and Soil series, focuses on advancements in microbial technologies towards harnessing the microbiome for improved crop productivity and health. The book provides insights into the diversity of endophytic microbiomes and their potential utility in agricultural production. As increased crop yield through chemical interventions have limit thresholds and alternative, natural, and/or integrated approaches are increasingly needed, this book serves as an ideal reference for researchers and students in the fields of agricultural biotechnology, biochemistry, environmental science, plant biology, agricultural sciences, and agricultural engineering.Microbia... inoculants provide ways in which food production efficiency can be improved. Plant growth-promoting soil organisms increase net crop uptake of soil nutrients, resulting in larger crops and higher yields of harvested food. These and other symbiotic associations between plants and microbes can ultimately be exploited for the increased food production necessary to feed the world, in addition to creating safer farming techniques that minimize ecological disruption.

  • Glycolysis

    Tissue-Specific Metabolic Regulation in Physio-pathological Conditions
    • 1 Edición
    • Rita Ferreira + 2 más
    • Inglés
    Glycolysis: Tissue-Specific Metabolic Regulation in Physio-Pathological Conditions provides an integrated overview of glycolysis, spanning basic biochemistry, patho-physiology and therapeutic applications. The book also instructs in methods available to study the involvement of the glycolytic events in healthy biology and disease pathology. It begins with an overview of fundamental glycobiology followed by chapters dedicated to glycolysis physiology in organs and systems, pathologic conditions related to glycolytic alterations, glycolysis as a therapeutic target and in drug discovery efforts, and methodological approaches to advance new glycolysis research. Disease areas considered range from cancer to heart failure, diabetes, inborn glycolytic pathway defects, hematologic malignancies, osteoporosis, neurodegenerative diseases and viral Infections. Omics and computational modeling, interactive study methods, and glycolysis flux measurement are described in detail, with step-by-step descriptions of experimental protocols, set-up and analysis.

  • Bacterial Secondary Metabolites

    Synthesis and Applications in Agroecosystem
    • 1 Edición
    • Kamel A. Abd-Elsalam + 1 más
    • Inglés
    Bacterial Secondary Metabolites: Synthesis and Applications in Agroecosystem presents the structure, properties, and biotechnological applications of bacterial metabolites and their upcoming industrial, pharmaceutical, antimicrobial, and anticancer applications. Chapters cover topics such as the use of lactic acid bacteria as an antifungal and antibacterial agent, bacterial siderophores structure and potential applications, and the role of cyanobacteria metabolites in disease management, amongst others. Plant and agri-food environmental scientists and researchers, graduate, and post-graduate students in related fields will benefit from this reference book which is published as part of the Nanobiotechnology for Plant Protection series.

  • The Biology of Ageing: From Hallmarks to Drugs

    • 1 Edición
    • Volumen 1
    • Richard Faragher
    • Inglés
    The Biology of Ageing: From Hallmarks to Drugs provides a series of reviews covering multiple aspects of the translational pipeline as interventions in the biology of ageing itself become a clinical reality. New chapters cover Cellular senescence and NAD+: what are the links?, Biomarker for ageing: potential and pitfalls, What chemists offer to ageing research, You are what you eat – or are you? Exploring dietary versus topical anti-oxidants in skin ageing, Clinical trials: A simple guide for gerontologists, Towards an ethical framework for geroscience, and more. The book explores links between known ageing mechanisms and new interventions, agents and actions at the nutraceutical-drug divide, the challenges and opportunities provided by biomarkers and chemistry- biology interface and lastly the ethical and operational challenges of clinical trials in the age of translational geroscience.

  • Snow Leopards

    • 2 Edición
    • Inglés
    Snow Leopards, Second Edition provides a foundational, comprehensive overview of the biology, ecology and conservation of this iconic species. This updated edition incorporates all the recent information from range-wide surveys and conservation projects, the results of technical and advances particularly in genetics, camera trapping and satellite tracking, and evaluates emerging threats. New chapters synthesize the novel scientific methods and statistical analyses used to develop density and population estimates and how they inform conservation and management estimates. Sections cover historical information, the main biogeographic patterns, evolutionary trends, conservational efforts, and cultural significance. Status and distribution are fully updated for all 12 countries where snow leopards occur. Other sections describe established and emerging threats, including human-wildlife conflict, illegal trade, infrastructure development, and climate change along with conservation solutions used to address these threats. The book concludes with a final section on global snow leopard initiatives and future potentials.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 117
    • Inglés
    Advances in Virus Research, Volume 117, the latest release in a series that highlights new advances in the field, includes invaluable updates written by an international board of authors. Chapters in this new release include Pathogenesis of neuroinvasive flaviviruses, Cellular entry and egress of astroviruses, Rift Valley Fever virus entry and infection, and more.

  • Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-Morbidity Factors Part B

    • 1 Edición
    • Volumen 172
    • Inglés
    Nanowired Delivery of Drugs and Antibodies for Neuroprotection in Brain Diseases with Co-morbidity Factors, Part B, Volume 172 in the International Review of Neurobiology series, includes chapters on Spinal cord injury induced exacerbation of Alzheimer's disease pathophysiology in the cord is reduced by topical application of nanowired cerebrolysin and antibodies to tumor necrosis factor alpha, Nanodelivery of histamine H3 receptor inverse agonist BF-2549 with clobenpropit a H3 receptor antagonist and H4 receptor agonist induced neuroprotection in spinal cord injury is potentiated by antioxidant compound H-290/51, and Neuromodulation and quality of life for patient with spasticity after spinal cord injury, and more.Other sections cover Efficacy of invasive and non-invasive methods for the treatment of Parkinson´s disease: nanodelivery and enriched environment, Co-administration of DL-3-n-butylphthalid... and neprilysin is neuroprotective in Alzheimer disease associated with brain injury, Nicotine Neurotoxicity Exacerbation following Engineered Ag and Cu (50-60 nm) nanoparticles intoxication, and Neuroprotection with nanowired delivery of antioxidant compound H-290/51 together with serotonin 5-HT3 receptor antagonist ondansetron.

  • Tutorials in Clinical Chemistry

    • 1 Edición
    • Ibrahim A. Hashim
    • Inglés
    Tutorials in Clinical Chemistry is designed for trainee pathology residents, clinical chemists, medical students, and clinical laboratory scientists, in addition to those preparing for board and postgraduate examination. It is helpful to those in training as well as a teaching aid for mentors, faculty, and directors. The book is organized into 17 system-based chapters covering essential pathophysiology, biochemical investigation, and technical aspects of relevance to results interpretation. Tutorials in Clinical Chemistry is a must-have, didactic and essential knowledge as well as practical resource for learning and review.

  • Encyclopedia of Food Safety

    • 2 Edición
    • Geoffrey W Smithers
    • Inglés
    Encyclopedia of Food Safety, Second Edition, Four Volume Set provides an authoritative one-stop reference work covering all aspects of the field. Specific focus lies in the book's coverage of key industry developments over the last ten years, including: (i) detailed understanding of infectious agents and toxins and their route into the food chain; (ii) sophisticated detection and identification methods; (iii) effective control mechanisms, like heat treatment, refrigeration and sanitizers; (iv) education of food processors, handlers and consumers about safe food handling practices; (v) sanctioned food production, processing, storage and transport control protocols, like HACCP; and (vi) a strong policy and regulatory environment. With approximately 270 outstandingly written chapters from the world’s leading experts in food science, the book covers all aspects of food safety along the entire food chain and in one complete work, thus providing the ideal reference tool for professionals working across the multiple scientific disciplines and technologies that constitute modern food safety.

  • Epigenetics in Human Disease

    • 3 Edición
    • Trygve O. Tollefsbol
    • Inglés
    Epigenetics in Human Disease, Third Edition examines the diseases and conditions on which we have advanced knowledge of epigenetic mechanisms, such as cancer, autoimmune disorders, aging, metabolic disorders, neurobiological disorders and cardiovascular disease. From molecular mechanisms and epigenetic technology to clinical translation of recent research, the nature and applications of the science is presented for those with interests ranging from the fundamental basis of epigenetics to therapeutic interventions for epigenetic-based disorders, with an emphasis throughout on understanding and application of key concepts in new research and clinical practice. Fully revised and up-to-date, this Third Edition discusses topics of current interest in epigenetic disease research, including stem cell epigenetic therapy, bioinformatic analysis of NGS data, epigenetic mechanisms of imprinting disorders, microRNA in cancer, epigenetic approaches to control obesity, epigenetics and airway disease, and epigenetics in cardiovascular disease. Further sections explore online epigenetic tools and datasets; early-life programming of epigenetics in age-related diseases; the epigenetics of addiction and suicide, and epigenetic approaches to regulating and preventing diabetes, cardiac disease, allergic disorders, Alzheimer’s disease, respiratory diseases, and many other human maladies. In addition, each chapter now includes chapter summaries, definitions, and vibrant imagery and figures to reinforce understanding, as well as step-by-step methods and disease research case studies.

  • Biophysics at the Nanoscale

    Applications of Functional Materials
    • 1 Edición
    • Adil Denizli
    • Inglés
    Biophysics at the Nanoscale: Applications of Functional Materials explores how nanomaterials and nanotechnology can be used effectively in biophysics. The book introduces the structures and functions of nanoscale-based materials from a biophysical perspective while also discussing nanotechnology opportunities for their purposeful manipulation and the integration of nanoscale-based materials with current top-notch tools and platforms to ultimately facilitate their potential applications in the areas like biomedicine and the pharmaceutical sciences. The book provides the most impactful research and current techniques and strategies. With contributions from an international group of experts in the field, the book is highly informative and is a reference point for learning key knowledge and information.

  • Peptide and Protein Drug Delivery Using Polysaccharides

    • 1 Edición
    • Aakanchha Jain + 1 más
    • Inglés
    Peptide and Protein Drug Delivery Using Polysaccharides offers an interdisciplinary discussion of polysaccharides applied in peptide and protein drug delivery. Chapters consider basic biology of different polysaccharides of current interest and their production at pilot and large-scale stages by various techniques including, but not limited to, cell and hairy root cultures. Other sections examine factors affecting polysaccharide absorption, metabolism, and excretion in nascent, encapsulated, or conjugated forms, with unique coverage of vaccine absorption, metabolism, and drug delivery. A final section considers analytical methods for detection in tissue fluids and homogenates. Accessible figures, tables, and graphical abstracts are included throughout to support understanding. Specific polysaccharides discussed for therapeutic purposes include cellulose, hyaluronic acid, heparin, carageenan, alginic acid, agar and myrrh, acacia, tragacanth, ghatti gum, chitin, chitosan, starch, glycogen and dextran.

  • Functional Neurological Disorder, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 41-4
    • David Perez + 1 más
    • Inglés
    In this issue of Neurologic Clinics, guest editosr Drs. David L. Perez and Sara A. Finkelstein bring their considerable expertise to the topic of Functional Neurologic Disorders. Top experts in the field cover issues such as functional movement disorder: assessment and treatment; functional cognitive disorder: diagnosis, treatment, and differentiation from secondary causes of cognitive dysfunction; functional speech and voice disorders: diagnosis and treatment; personalizing clinical care in functional neurological disorder: a biopsychosocial-info... perspective; and more.

  • Advances in Pig Welfare

    • 2 Edición
    • Irene Camerlink + 1 más
    • Inglés
    Advances in Pig Welfare, Second Edition continues its complete coverage of the field with fully updated information and analysis of current issues in the key areas of pig welfare. It is a comprehensive review covering both recent developments and persistent welfare issues. The book has been expanded with 10 new chapters addressing the most relevant and significant issues in industry with a more global perspective.The book is divided into four sections, starting with an introduction (Part 1) to major topics in pig welfare, such as pigs’ needs, including affective states and positive animal welfare. Part two provides an overview of production systems and reviews welfare hotspots and mitigation. Part three covers pig welfare management topics, such as pig-human interactions and precision livestock farming. Global perspectives on pig welfare, including economics, legislation, farmers attitudes and climate change, are covered in Part 4.Written by an international team of renowned researchers in the field, the book continues to be a useful resource for practicing vets involved in welfare assessment, welfare research scientists and students, and indeed, anyone with a professional interest in the welfare of pigs.

  • Steroid Biochemistry

    • 1 Edición
    • Volumen 689
    • Inglés
    Steroid Biochemistry, Volume 688 in the Methods of Enzymology series, highlights new advances in the field, containing chapters on a variety of timely topics, including Cytochrome P450 Enzyme, Steroidogenic P450s (CYP11A1, 17A1, 21A2, 11B1, and 11B5), Steroid 17 alpha-hydroxylase/17... (Cytochrome P450 17A1), Enzymes of Estrogen Biosynthesis, Aromatase and Steroid Sulfatase, Estrogenic 17b-Hydroxysteroid Dehydrogenase, Hydroxysteroid Dehydrogenases (HSD), 3a-Hydroxyssteroid Dehydrogenase, Approaches to Measuring 3b-Hydroxysteroid Dehydrogenase Type 1, 3b-Hydroxysteroid Dehydrogenase Type 2, and much more.

  • Nanotechnological Aspects for Next-Generation Wound Management

    • 1 Edición
    • Pratima R. Solanki + 4 más
    • Inglés
    Nanotechnological Aspects for Next-generation Wound Management provides detailed, up-to-date literature on nanotechnology's role in wound management and its applications using nanoparticles, nanocomposites, carbon-based nanostructures and nanomaterials. Scaffolds, three-dimensional approaches, skin tissue engineering, and polymer-based films are discussed to treat wounds. This one-of-a-kind reference is ideal for health practitioners, clinicians and researchers who will find the book to be excellent reference material for updates on recent trends in nanotechnology for wound management.

  • Biodiversity and Bioeconomy

    Status Quo, Challenges, and Opportunities
    • 1 Edición
    • Kripal Singh + 2 más
    • Inglés
    Biodiversity and Bioeconomy: Status Quo, Challenges, and Opportuniti es comprehensively delivers the latest developments in theories of biodiversity and ecosystem functi oning and their major implicati ons for biodiversity conservati on through diversifying agriculture, forestry, and biomass producti on systems and linking these developments with sustainability of bioeconomy.This book provides basic understanding of biodiversity and bioeconomy, diff erent views of their interrelati onship, and their links with sustainable development goals. It also examines the research and practi ce of biodiversity and ecosystem functi oning in agriculture, forestry,and biomass producti on systems to achieve sustainable bioeconomy. Finally, this book examines status, challenges, and opportuniti es for biodiversity-centere... bioeconomy providing a way forward.

  • Antidiabetic Medicinal Plants

    Applications and Opportunities
    • 1 Edición
    • M. Naeem + 1 más
    • Inglés
    Antidiabetic Medicinal Plants: Applications and Opportunities presents new developments that are impacting the use of plants to address diabetic conditions. Presenting multiple perspectives on these plants, their identification, cultivation and application, this book presents the state-of-the-art with an eye toward the future. Presented in five parts, the book first provides an overview of plants with antidiabetic properties, then moves to the agricultural practices for the cultivation and production of those plants. Part Three focuses on the chemical composition and phytochemicals of the plants before then moving into a study of the physiological, biotechnological, and molecular approaches to optimizing these plants.The book concludes with insights into current and potential future medical and clinical applications, making it ideal for those seeking to understand the biology and chemistry of plants with anti-diabetic properties and their effective development and application.

  • Functional Dietary Lipids

    Food Formulation, Consumer Issues, and Innovation for Health
    • 2 Edición
    • Thomas A. B. Sanders
    • Inglés
    Functional Dietary Lipids: Food Formulation, Consumer Issues and Innovation for Health, Second Edition discusses this important component of the human diet and the ways it plays an essential functional role. As with the previous edition, this book covers the functionality and nutritional benefits of dietary fat in food in terms of formulation, manufacturing and innovation for health. It contains approximately 35% new content, including 5 new chapters as well as updated content in previous chapters. New content covers the health effects of fat-soluble compounds, the sustainability aspects of vegetable oil production; process engineering of fats to improve functionality and quality, and more. This second edition also includes updated data on regulations, including nutritional profiling, signposting, taxation and advertising restrictions, and the regulatory approval of novel sources of lipids. This book will be a useful reference for those wanting to explore human nutrition and dietary lipids as well as those involved in decision-making surrounding food formulation and manufacturing.

  • Stem Cells and Signaling Pathways

    • 1 Edición
    • Surajit Pathak + 1 más
    • Inglés
    Stem Cells and Signaling Pathways brings together chapters exploring the mechanism of stem cells and the signaling pathways. This book is a very concise and easy-to-use book. It serves as an ideal reference to guide investigators towards further valuable answers on the role of stem cells and will aid basic researchers and scientists in biomedical sciences and tissue engineering and regenerative medicine with a wide variety of interests in stem cell biology linking basic signal transduction for possible future therapies directed to treatments and different diseases.Significant information on signaling has been presented here. Sufficient knowledge has been provided on therapeutic approaches for the treatment of different degenerative disorders.

  • Neuropsychiatric Disorders and Epigenetics

    • 2 Edición
    • Jacob Peedicayil + 1 más
    • Inglés
    Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions when the effects of environmental stimuli on epigenetic states is particularly relevant to disease. This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy.

  • Non-Conventional Starch Sources

    Properties, Functionality, and Applications
    • 1 Edición
    • José Manuel Lorenzo + 1 más
    • Inglés
    Non-Conventional Starch Sources: Properties, Functionality, and Applications presents the use of non-conventional, unutilized, and underutilized sources to isolate, characterize and functionalize starches. Specific attention is paid to the sources’ application in foods as well as their incorporation into packaging through films and coatings. Broken into seven sections, this book addresses sources from fruit seeds, cereals and millets, pseudo-cereals, seeds, roots and tubers, rhizome and legumes. Food scientists, technologists and students and researchers studying related fields will benefit from this important reference.

  • Treatment-Resistant Depression Part B

    • 1 Edición
    • Volumen 281
    • Inglés
    Treatment-Resistant Depression, Part B, Volume 281 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on highly relevant topics such as Treatment Resistant Depression in Children and Adolescents, Treatment Resistant Depression in Elderly, Brain Stimulation for Treatment Resistant Depression, Electroconvulsive Therapy for Treatment Resistant Depression, Psychological aspects and Psychotherapy for Treatment Resistant Depression, Psychiatric Rehabilitation and Cognitive Deficit for Treatment-Resistant Depression, Insomnia and Treatment Resistant Depression, and Tinnitus and Treatment Resistant Depression.

  • Pediatric Head and Neck Imaging, An Issue of Neuroimaging Clinics of North America

    • 1 Edición
    • Volumen 33-4
    • William T. O'Brien Sr.
    • Inglés
    In this issue of Neuroimaging Clinics, guest editor Dr. William T. O'Brien, Sr., brings his considerable expertise to the topic of Pediatric Head and Neck Imaging. The differential diagnosis of neck masses in pediatric patients differs compared to masses that arise in adults. In this issue, top experts in the field discuss imaging of hearing loss, sinus infections, neck masses, and congenital lesions, and more.

  • Phage Therapy - Part B

    • 1 Edición
    • Volumen 201
    • Inglés
    Phage Therapy - Part B, Volume 201 covers bacteriophage and their isolation, screening, synthetic phage, diagnostics, directed evolution, host interaction, and more. The book's aim is to highlight a number of aspects of phage in a way that can help students, researchers, clinicians, entrepreneurs and stakeholders perform research. Sections cover Phages for the treatment of Pseudomonas aeruginosa infection, Phage for the treatment of Vibrio cholerae infection, Phages for the treatment of Mycobacterium species, Phage therapy for gut microbiome, Phages as delivery vehicles, Phage display, Unlocking the potential of Phages: Innovative Approaches to harnessing Bacteriophages as Diagnostic Tools for Human Diseases, and more. Other sections explore Phage display and human disease detection, Bacteriophage as Cargo and its application in nanomedicine, Phage for drug delivery vehicles, Genome editing for phage design and uses for therapeutic applications, Phage for cancer therapy, and Phage for regenerative medicine and cosmetics.

  • Advances in Stem Cells and their Niches

    • 1 Edición
    • Volumen 7
    • Susie Nilsson
    • Inglés
    Advances in Stem Cells and their Niches, Volume Seven highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Chromatin Remodeling Complexes and Transcriptional Coregulators

    • 1 Edición
    • Volumen 53
    • Inglés
    Chromatin Remodeling Complexes and Transcriptional Coregulators, Volume 53, the latest release in The Enzymes series highlights new advances in the field, with interesting new chapters that cover Perspectives on Chromatin Remodeling, The functions of ISWI-type remodelers in yeast, Conserved mechanisms of NuRD function in hematopoietic gene expression, The SIN3 complex as a metabolic epigenetic regulator, Soft repression and chromatin modification by conserved transcriptional corepressors, The NPAC-LSD2 complex in nucleosome demethylation, Role of intrinsically disordered domains in transcriptional regulation, and Regulation of the Recovery of Cancer from Therapy Exposure by Noncoding RNAs.

  • Chromatin Readers in Health and Disease

    • 1 Edición
    • Volumen 35
    • Olivier Binda
    • Inglés
    Chromatin Readers in Health and Disease, Volume 35, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD, SRA, and Methyl-RNA readers.In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders.

  • Medical Image Analysis

    • 1 Edición
    • Alejandro Frangi + 2 más
    • Inglés
    Medical imaging is increasingly at the base of many breakthroughs in biomedical sciences, becoming a fundamental enabling technology of biomedical scientific progress. Medical Image Analysis presents practical knowledge on medical image computing and analysis and is written by top educators and experts in the field. This text is a modern, practical, broad, and self-contained reference that conveys a mix of essential methodological concepts within different medical domains, reflecting the nature of the discipline today, making it suitable as a course text and a self-learning resource.

  • Fungal Secondary Metabolites

    Synthesis and Applications in Agroecosystem
    • 1 Edición
    • Heba I. Mohamed + 1 más
    • Inglés
    Fungal Secondary Metabolites: Synthesis and Applications in Agroecosystem presents the properties and biotechnological applications of fungal metabolites and their industrial, pharmaceutical, antimicrobial, and anticancer applications.Chapter... cover topics including the role of fungal metabolites in the management of biotic or abiotic stress, microbial alkaloids and their pharmaceutical and agricultural applications, and fungal metabolites as novel plant pathogen antagonists. In order to develop novel bioactive compounds, researchers must understand the agricultural applications of fungal metabolites. This book provides expert insights from around the globe highlighting the latest understanding and future prospects for their use.Plant and agri-food environmental scientists, researchers, graduate, and post-graduate students in related fields will find value in this reference book which is published as part of the Nanobiotechnology for Plant Protection series.

  • Inoculating Cities

    Case Studies of the Urban Response to the COVID-19 Pandemic
    • 1 Edición
    • Rebecca Katz + 1 más
    • Inglés
    Inoculating Cities: Case Studies of the Urban Response of the COVID-19 Pandemic uses detailed case studies to document and describe how cities located in high, middle and low-income countries responded to the COVID-19 pandemic. City governments and municipal authorities exist and operate in extremely varied contexts (i.e., socioeconomic, demographic, legal and governance, etc.) and intentionally documenting the experiences in these different contexts provides guidance to decision-makers for future preparedness and response activities. This volume highlights the innovative solutions throughout the pandemic as described by the people who designed and implemented pandemic response efforts in their cities. In addition, it identifies successful models that can be adopted in the future by city leaders around the world.

  • Crystallography of Protein Dynamics

    • 1 Edición
    • Volumen 688
    • Inglés
    Crystallography of Protein Dynamics, Volume 688, the latest release in this important series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Adenosine A2A Receptor Antagonists

    • 1 Edición
    • Volumen 170
    • Inglés
    Adenosine A2A Receptor Antagonists, Volume 170 in the International Review of Neurobiology series highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including A2A Adenosine Receptor Agonists, Antagonists, Inverse Agonists and Partial Agonist, Chemistry – agonists, antagonists, partial agonists, inverse agonists, Functional roles of adenosine receptors – biochemistry and neuronal plasticity, A2A and Depression, A2AR and glial function, The adenosine A2A receptor in the basal ganglia: expression in health and disease, heteromerization, functional selectivity and signaling, How and why A2a receptor become to be a therapeutic target in Parkinson’s disease therapy, and much more.

  • Circulating Tumor Cells, From Biotech Innovation to Clinical Utility Part A

    • 1 Edición
    • Volumen 381
    • Inglés
    "Circulating Tumor Cells, from biotech innovation to clinical utility" provides an overview of the most recent technological and clinical advances with regards to the study of circulating tumor cells (CTCs) in solid tumors. The volumes cover studies on CTCs in breast, prostate, colorectal and lung cancer, with a focus on clinical utility, and also include methodological and biological topics such as CTC culture, multi-omic characterization of CTCs, atypical CTC populations and interaction between CTCs and immunity.

  • Hydrogels for Tissue Engineering and Regenerative Medicine

    From Fundamentals to Applications
    • 1 Edición
    • J. Miguel Oliveira + 2 más
    • Inglés
    Hydrogels for Tissue Engineering and Regenerative Medicine: From Fundaments to Applications provides the reader with a comprehensive, concise and thoroughly up-to-date resource on the different types of hydrogels in tissue engineering and regenerative medicine. The book is divided into three main sections that describe biological activities and the structural and physicochemical properties of hydrogels, along with a wide range of applications, including their combination with emerging technologies. Written by a diverse range of international academics for professionals, researchers, undergraduate and graduate students, this groundbreaking publication fills a gap in literature needed in the tissue engineering and regenerative medicine field.

  • Phage Therapy - Part A

    • 1 Edición
    • Volumen 200
    • Inglés
    Phage Therapy - Part A, Volume 200 is an informative text on phage and their use for treatment in bacterial infections. The book highlights a number of aspects of the phage in a way that can help students, researchers, clinicians, entrepreneurs and stakeholders perform their research with great interest. Chapters in this new release cover An introduction to bacteriophage and their therapeutic applications, Isolation, screening and characterization of phage, Synthetic phage and their application in phage therapy, Phage engineering for development of diagnostic tools, Phage design and directed evolution to evolve phage for therapy, and more. Additional sections cover Host-phage interactions and modelling for therapy, Phage and phage cocktails formulations, Phage for treatment of Escherichia coli infection, Phage for treatment of Klebsiella pneumoniae infection, Phage for treatment of Salmonella spp infection, Phage for treatment of Staphylococcus aureus infection, and Phages for treatment of Acinetobacter baumannii infection.

  • Nanotechnology and Nanomaterials in the Agri-Food Industries

    Smart Nanoarchitectures, Technologies, Challenges, and Applications
    • 1 Edición
    • Pardeep Singh + 4 más
    • Inglés
    Nanotechnology and Nanomaterials in the Agri-Food Industries: Smart Nanoarchitectures, Technologies, Challenges, and Applications brings together the latest advances in the utilization of advances nanotechnology, nanoarchitectures, and nanomaterials in the agricultural and food sectors. The book begins by discussing recent trends towards sustainable synthesis and application, covering green nanomaterials and biodegradable nanomaterials and composites. Subsequent chapters focus on key application areas of engineered nanomaterials in both agriculture and food processing, such as crop production and protection, delivery vehicles, detection of contaminants, nanobionic and genetic engineering in plants, active food packaging and preservation, enhanced food formulations and nutrients, nanoscale additives for freshness, and nanosensors. This is followed by a section that addresses key challenges relating to the application of nanostructures and nanodevices in these sectors, including global market considerations, health and environmental concerns, and intellectual property and socio-economic issues. Finally, policy implications and future perspective for the field are reviewed in detail.

  • Viral Diseases of Field and Horticultural Crops

    • 1 Edición
    • L. P. Awasthi
    • Inglés
    Viral Diseases of Field and Horticultural Crops details the fundamental and applied aspects of the viral diseases of field and horticultural crops. The book opens with a historical introduction to plant virology, important plant virologists, and landmarks. It continues with systematic coverage of viral diseases, their economic significance, disease symptoms, host range, mode of transmission, diagnostic techniques, geographic distribution, epidemiology, yield losses, and control and management of the disease. Contributions from an international group of virologists with a wide range of academic, research, professional, and specialized backgrounds in plant virology makes Viral Diseases of Field and Horticultural Crops a comprehensive and must-have resource for those engaged in the study and research of plant virology, microbiology, and plant pathology particularly viral diseases and their impact on field and horticultural crops.

  • Nutrición comunitaria

    • 4 Edición
    • Javier Aranceta Bartrina
    • Español
    Nutrición comunitaria es el texto en castellano referente en la disciplina con casi 30 años de historia, dirigido por el Dr. Javier Aranceta, un reconocido experto en la aplicación de la nutrición comunitaria tanto a nivel local como en los países latinoamericanos. Está dirigido tanto a estudiantes de Nutrición como Medicina y otros grados de Ciencias de la Salud. La nueva edición sigue la misma filosofía de las anteriores, es decir presentar de forma clara y de fácil comprensión todos los aspectos relevantes en la disciplina. Esta edición incorpora 9 nuevos capítulos. Especial atención merecen los correspondientes al papel de la microbiota y el de las 7 “S” de la Agenda de 2030.

  • Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine

    • 1 Edición
    • Tapan Kumar Giri + 2 más
    • Inglés
    Polysaccharide Hydrogels for Drug Delivery and Regenerative Medicine is an archival reference for researchers, students and scientists working on hydrogels based on microbial and animal sources. The book contains Information regarding their synthesis, characterization, and applications in the field of drug delivery and regenerative medicine. Each chapter addresses a separate polysaccharide hydrogel and its suitability in drug delivery and/or regenerative medicine. This is a novel resource that brings together a panel of highly accomplished experts in the field of natural polysaccharides to discuss basic causes and specific problems related to drug delivery and regenerative medicine.

  • Advances in Food and Nutrition Research

    • 1 Edición
    • Volumen 106
    • Fidel Toldra
    • Inglés
    Advances in Food and Nutrition Research, Volume 107 provides the latest advances on emerging bioactive compounds with putative health benefits and their controlled release and application in foods and nutraceuticals, as well as information on food technologies, including 3D printing, safety of raw materials, and viruses in foods. Chapters in this new release cover Tackling food allergens - the role of food processing on proteins’ allergenicity, Plant bioactive peptides for cardiovascular disease prevention, Caffeine and sport, Nanostructured steady-state nanocarriers for nutrients preservation and delivery, Flavor perception and health benefits of tea, Next Generation Plant-based Meat Alternatives: Sources, manufacturing and consumer acceptance, and more. Other sections cover Bioprotective cultures and bacteriocins as food preservatives and Raman Spectroscopy: principles and recent applications in Food Safety.

  • Autophagy Processes and Mechanisms

    • 1 Edición
    • Rohan Dhiman + 1 más
    • Inglés
    Autophagy Processes and Mechanisms details the process of autophagy and its significance in diseases and aging. It provides insights into autophagy mechanisms and processes to broaden our understanding. By collecting recent progress on several aspects of the autophagy process, it provides a more integrative perspective and serves as a resource that can influence future research initiatives in the field. This new book is appropriate for basic and applied researchers in cell biology, biologists and those working in the pharmaceutical sciences.

  • Pharmaceutics

    Basic Principles and Application to Pharmacy Practice
    • 2 Edición
    • Alekha Dash + 1 más
    • Inglés
    Pharmaceutics: Basic Principles and Application to Pharmacy Practice, Second Edition is a valuable textbook covering the role and application of pharmaceutics within pharmacy practice. This updated resource is geared toward meeting and incorporating the current curricular guidelines on pharmaceutics and laboratory skills mandated by the American Council for Pharmacy Education. It includes a number of student-friendly features, including chapter objectives and summaries, practical examples, case studies, numerous images and key-concept text boxes. Two new chapters are included, as well as a new end of chapter section covering "critical reflections and practice applications". Divided into three sections – Physical Principles and Properties of Pharmaceutics; Practical Aspects of Pharmaceutics; and Biological Applications of Pharmaceutics – this new edition covers all aspects of pharmaceutics and providing a single and compelling source for students.

  • Biological Invasions and Global Insect Decline

    • 1 Edición
    • Jonatan Rodríguez + 2 más
    • Inglés
    Biological Invasions and Global Insect Decline offers the most updated knowledge on how invasive alien species affect insect diversity worldwide. The book provides ongoing research and the most relevant information, covering the main aspects of the impact of biological invasions as well as future insights on mitigation and consequences. It discusses how the introduction of all kinds of organisms, from bacteria and plants to vertebrates, affect current declines in insect diversity. The latter portion of the book delves into existent and future monitoring and management programs, including citizen science and regenerative ecology as socio-ecological solutions to combat these threats. Written and edited by international experts on invasion ecology and insect conservation, this book explores the role of global change and the introduction of invasive species in altering the structure of habitats and how this induces a global insect decline. This will be a valuable resource for entomologists, invasion biologists and other researchers in biodiversity conservation, as well as practitioners and stakeholders concerned about problematic invasive alien species and insect population decline.

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