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Elsevier

Libros en Ciencias de la Vida

  • Smart Polymeric Nano-Constructs in Drug Delivery

    Concept, Design and Therapeutic Applications
    • 1 Edición
    • Suresh P Vyas + 2 más
    • Inglés
    Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems.

  • Tissue Engineering

    • 3 Edición
    • Clemens van Blitterswijk + 1 más
    • Inglés
    Tissue Engineering, Third Edition provides a completely revised release with sections focusing on Fundamentals of Tissue Engineering and Tissue Engineering of Selected Organs and Tissues. Key chapters are updated with the latest discoveries, including coverage of new areas (skeletal TE, ophthalmology TE, immunomodulatory biomaterials and immune systems engineering). The book is written in a scientific language that is easily understood by undergraduate and graduate students in basic biological sciences, bioengineering and basic medical sciences, and researchers interested in learning about this fast-growing field.

  • Himalayan Fruits and Berries

    Bioactive Compounds, Uses and Nutraceutical Potential
    • 1 Edición
    • Tarun Belwal + 2 más
    • Inglés
    Himalayan Fruits and Berries: Bioactive Compounds, Uses and Nutraceutical Potential presents nutraceutical fruits and berries from the Himalayan region and highlights their potential use in nutraceutical products. Beginning with the introduction of the Himalayan region and its wild fruits, this book explores various kinds of wild fruits and berries. It includes coverage of traditional, ethnomedicinal, and local uses of potential nutraceutical fruits and analyzes their distribution, availability, and cultivation methods. The book also provides a detailed summary of clinical studies and presents "from field to industry" case studies. Wild fruits and berries play an important role in mitigating hunger in the developing world, and these fruits are consumed either in whole or extracted for use in nutraceutical production. Nutrition researchers, food scientists, food chemists, plant scientists, pharmacologists, as well as students or researchers working in pharmaceutical and nutraceutical industries exploring the use of Himalayan wild berries and fruits as new components and sources in nutraceuticals will benefit from this book.

  • Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies

    • 1 Edición
    • Volumen 1
    • Shi Hu
    • Inglés
    Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies presents a description of the sensitizers used to overcome resistance to anti-EGFR targeted antibody therapies in cancer, including novel engineered antibody drugs and other sensitizers. The book gives insights into the landscape of anti-EGFR based cancer treatments, the challenges of targeted therapy, and a glimpse into the future of antibody therapy. It offers pertinent science information on strategies used for the rational design and discovery of novel sensitizing agents, and in addition, translational studies involving pre-clinical and clinical design. This book is an indispensable resource for cancer researchers, medicinal chemists and other biomedical scientists.Finally, the book covers basic science strategies used in drug discovery and preclinical evaluation focused on EGFR blockage resistance, as well as clinical trial methodology, including clinical pharmacokinetics and imaging to address issues of efficacy evaluation of the new anticancer sensitizers for anti-EGFR drug resistance.

  • Visualization Techniques for Climate Change with Machine Learning and Artificial Intelligence

    • 1 Edición
    • Ashutosh Kumar Dubey + 4 más
    • Inglés
    Visualization Techniques for Climate Change with Machine Learning and Artificial Intelligence covers computer-aided artificial intelligence and machine learning technologies as related to the impacts of climate change and its potential to prevent/remediate the effects. As such, different types of algorithms, mathematical relations and software models may help us to understand our current reality, predict future weather events and create new products and services to minimize human impact, chances of improving and saving lives and creating a healthier world. This book covers different types of tools for the prediction of climate change and alternative systems which can reduce the levels of threats observed by climate change scientists. Moreover, the book will help to achieve at least one of 17 sustainable development goals i.e., climate action.

  • Quinoa

    Chemistry and Technology
    • 1 Edición
    • Fan Zhu
    • Inglés
    Quinoa: Chemistry and Technology provides an overview of the chemistry, processing, and technology of quinoa grain and its components, covering the development of quinoa grain in different parts of the world for food production, including its structure, molecular and chemical composition, milling properties, processing characteristics, and food products. Increasing demand for plant-based, gluten-free foods that are nutritious, healthy, sustainable, and affordable has caused quinoa cultivation to expand to over 70 countries due to its attractive nutritional and food security properties. This practical resource is designed to support the development of quinoa in different sectors, such as the food industry.

  • Viral Infections and Antiviral Therapies

    • 1 Edición
    • Amal Kumar Dhara + 1 más
    • Inglés
    Viral Infections and Antiviral Therapies provides comprehensive coverage of viral infections and their transmission. Coverage includes antiviral agents, therapeutics, their mechanisms and treatment strategies. The book is organized into four sections, including an introduction to antiviral therapies, viral infections and their transmission, antiviral agents and therapeutics, and a market overview and future developments. The chapters in each section of the book discuss various key topics that are contributed to by an international group of leading experts.

  • Applications of Artificial Intelligence in Medical Imaging

    • 1 Edición
    • Abdulhamit Subasi
    • Inglés
    Applications of Artificial Intelligence in Medical Imaging provides the description of various biomedical image analysis in disease detection using AI that can be used to incorporate knowledge obtained from different medical imaging devices such as CT, X-ray, PET and ultrasound. The book discusses the use of AI for detection of several cancer types, including brain tumor, breast, pancreatic, rectal, lung colon, and skin. In addition, it explains how AI and deep learning techniques can be used to diagnose Alzheimer's, Parkinson's, COVID-19 and mental conditions. This is a valuable resource for clinicians, researchers and healthcare professionals who are interested in learning more about AI and its impact in medical/biomedical image analysis.

  • Thermal Processing of Food Products by Steam and Hot Water

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari
    • Inglés
    Thermal Processing of Food Products by Steam and Hot Water, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for the thermal processing of different food products by applying steam and hot water. Sections cover an overview of thermal food processing, heat exchangers in the food processing industry, different thermal processing operations in the food industry, and applications of heat exchanges. All sections emphasize basic texts relating to experimental, theoretical, computational and/or the applications of food engineering principles and relevant processing equipment. Written by experts in the field of food engineering, in a simple and dynamic way, this book targets industrial engineers working in the field of food processing and within food factories to make them more familiar with the particular food processing operations and equipment.

  • Droplets of Life

    Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid-Liquid Phase Separation
    • 1 Edición
    • Vladimir N. Uversky
    • Inglés
    Droplets of Life: Membrane-Less Organelles, Biomolecular Condensates, and Biological Liquid–Liquid Phase Separation provides foundational information on the biophysics, biogenesis, structure, functions, and roles of membrane-less organelles. The study of liquid–liquid phase separation has attracted a lot of attention from disciplines such as cell biology, biophysics, biochemistry, and others trying to understand how, why, and what roles these condensates play in homeostasis and disease states in living organisms. This book's editor recruited a group of international experts to provide a current and authoritative overview of all aspects associated with this exciting area.Sections introduce membrane-less organelles (MLOs) and biomolecular condensates; MLOs in different sizes, shapes, and composition; and the formation of MLOs due to phase separation and how it can tune reactions, organize the intracellular environment, and provide a role in cellular fitness..

  • Plant Transcription Factors

    Contribution in Development, Metabolism, and Environmental Stress
    • 1 Edición
    • Vikas Srivastava + 3 más
    • Inglés
    Plant Transcription Factors: Contribution in Development, Metabolism, and Environmental Stress provides comprehensive coverage of plant TFs and their various functions, evaluating their crucial role in growth and development, signaling, stress management and other key plant processes. Sections cover the significance of plant TFs in functional genomics, the influence of phyto-hormones on the modulation of plant TFs, plant development and metabolism, including shoot development, flowering development and alkaloid biosynthesis. The book's final section reviews the role of TFs in various plant stresses, including temperature, water and heavy metal stress. Written by leading experts around the globe, this book is an essential read to researchers interested in plant signaling and plant genomics.

  • G Protein-Coupled Receptors - Part A

    • 1 Edición
    • Volumen 193
    • Inglés
    G Protein-Coupled Receptors, Part A, Volume 193 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field. G protein-coupled receptors (GPCRs) represent the largest class of cell surface proteins with an intricate involvement of nearly every physiological process in our body. Approximately, one third of the clinically prescribed medicines target GPCRs and the quest to improve the exiting GPCR-targeting therapeutics continues. These two volumes are focused on activation, signaling and regulation of GPCRs with specific examples of receptor systems and cellular processes.

  • Ion Transport and Membrane Interactions in Vascular Health and Disease

    • 1 Edición
    • Volumen 90
    • Inglés
    Ion Transport and Membrane Interactions in Vascular Health and Disease, Volume 90 in the Current Topics in Membranes series, highlights advances in the field, with this new volume including chapters on an Introduction to Ion transport and membrane interactions in vascular health and disease, Endothelial cell microdomains of Ca2+ and metabolism, Cytoplasmic nanojunctions between smooth muscle organelles control specific Ca2+ signaling, TRPML channels in coronary vascular phenotypic modulation and calcification, Local voltage-gated Ca2+ channel regulation of vascular smooth muscle in diabetes, Biphasic changes in smooth muscle Ca2+ transporters during the progression of coronary atherosclerosis, Role of K+ channels in atherosclerosis, and more.

  • Advances in Immunology

    • 1 Edición
    • Volumen 155
    • Inglés
    Advances in Immunology, Volume 155, the latest release in this ongoing serial, highlights new advances in the field with this new volume presenting interesting chapters written by an international board of authors. Sections of note cover B cell/GC material.

  • Neuroimaging in Parkinson’s Disease and Related Disorders

    • 1 Edición
    • Marios Politis + 2 más
    • Inglés
    Neuroimaging in Parkinson’s Disease and Related Disorders discusses the advances of molecular, structural and functional neuroimaging techniques associated with the etiology, pathophysiology, effects and complications of novel therapies in Parkinson’s and related disorders. With new neuroimaging methodologies emerging over the past five years, this book provides a comprehensive overview of new technologies and research. Sections discuss the biomarker value of neuroimaging of the brain to understand disease progression in vivo in actual patients with Parkinson’s disease and related disorders. Readers will be updated on in vivo pathology and pathophysiology in Parkinson’s disease and in a number of related disorders. Also discussed is the association between clinical symptoms, clinical progression, and molecular, structural, and functional changes in the brain of patients with Parkinson’s disease and related disorders.

  • Biochemistry, Nutrition, and Therapeutics of Black Cumin Seed

    • 1 Edición
    • Abdalbasit Adam Mariod
    • Inglés
    Biochemistry, Nutrition, and Therapeutics of Black Cumin Seed covers the history of medicinal uses of N. sativa and its position in various cultures, agronomy, cultivation and agricultural practices. The book also brings the biochemical composition, carbohydrates, polysaccharides and nutritional value of black cumin seeds, while also exploring them as a potential functional food. Written by an international team of black cumin seeds researchers, this book aims to reach producers, nutraceuticals and pharmaceutical companies, unconventional oil producing companies, seed oils researchers, Institutes and research groups of medicinal plants, Food and chemistry students what they need to understand about the black cumin seed. Black cumin's application as a food additive and flavoring agent have been reported in various countries around the world. Furthermore, previous studies have identified many volatile components present in N. sativa seeds, including thymoquinone, a main compound that has antioxidant, antimicrobial, anti-malarial, anti-cancer activities and help in treatment of bronchial asthma, ischemia and cardiovascular diseases, besides many other compounds that can induce pharmacological effects and have therapeutic potential in humans.

  • Systems and Signal Processing of Capnography as a Diagnostic Tool for Asthma Assessment

    • 1 Edición
    • M. B. Malarvili + 4 más
    • Inglés
    Systems and Signal Processing of Capnography as a Diagnostic Tool for Asthma Assessment provides a comprehensive overview of groundbreaking tools and techniques for the diagnosis and monitoring of asthma. Sections cover an introduction to the human respiratory system and the pathophysiology of asthma before analyzing current assessment concepts, tools and techniques. The book describes spirometry and the peak flow meter as existing tools in assessing asthma along with their limitations. In addition, a detailed description of capnography as a new approach is included with various studies conducted on its analysis. Academicians and researchers in biomedical engineering, particularly in the course of biomedical signal processing and biomedical instrumentation will find the book useful.

  • Liquid Biopsy

    New Challenges in the era of Immunotherapy and Precision Oncology
    • 1 Edición
    • Antonio Russo + 3 más
    • Inglés
    Liquid Biopsy: New Challenges in the era of Immunotherapy and Precision Oncology aims to describe links between cancer, precision oncology, and liquid biopsy, focusing on their participation to immunotherapy management. The book provides updated information on the main applications of liquid biopsy and immunotherapy as well as interesting aspects useful for planning basic and translational research activities. It helps readers understand the central aspects of precision medicine in oncology, including the use of new generation technologies for translational and diagnostic settings and the main clinical trials in this area that may be useful during their research.The book is a valuable source for cancer researchers, oncologists and other members of the medical and biomedical field who are interested in learning more about recent developments in liquid biopsy and its relationship with precision medicine and immunotherapy.

  • Non-thermal Food Processing Operations

    Unit Operations and Processing Equipment in the Food Industry
    • 1 Edición
    • Seid Mahdi Jafari + 1 más
    • Inglés
    Non-thermal Food Processing Operations, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for the recent invented non-thermal processing of different food products. Divided into six sections, “Ozonation operations “, “Plasma processing operations”, “Irradiation operations”, “Pulsed electric fields processing operations”, “High pressure processing operations”, and “Radio frequency processing operations”, all chapters emphasize basic texts relating to experimental, theoretical, computational and/or applications of food engineering principles and the relevant processing equipment needed to low-temperature unit operations. Written by experts in the field of food engineering in a simple and dynamic way, this book targets Industrial Engineers and food factory workers from the field of food processing. Readers of the book will find information that will help them become more familiar with food processing operations and equipment.

  • Starchy Crops Morphology, Extraction, Properties and Applications

    • 1 Edición
    • Marney Pascoli Cereda + 1 más
    • Inglés
    Starchy Crops Morphology, Extraction, Properties and Applications is the first volume of the "Underground Starchy Crops of South American Origin" book series. Organized in five volumes, this series brings information on the applied level of producing and using starch from a range of plants grown in tropical and subtropical areas that have South American origin. This book presents the characteristics and properties of starches for raw materials grown in tropical climates. It allows comparing starches from 3 types of storage organs, roots, tubers and rhizomes, with different morphological structures and physiology. It contains the methodologies of extraction and analysis, describing the commercial process with the commercial equipment’s and its by-products and wastes. It also includes topics on fraud detection, nutritional aspects, and starch structure. Edited by a team of experts with solid background on starch extraction research, the books are aimed at all those involved in research and development as well as quality control and legislation in the field of starch.

  • Endophytic Association: What, Why and How

    • 1 Edición
    • Maulin P. Shah + 1 más
    • Inglés
    Endophytic Association: What, Why, and How focuses on the endophytic association of plants, how they have originated inside the host, their importance, and how they are beneficial for the environment, as well as humans. The book discusses how using endophytic microbes in agricultural fields can be enriched without impacting environment negatively, and how they can be utilized for pharmaceutical purposes, including bioremediation. It includes advanced and up-to-date information, as well as future directions for young researchers and scientists who are working in the field of agriculture, pharmaceuticals, bio nanotechnology and bioremediation of environmental contaminants for environmental protection and sustainable development.

  • Nanotechnology Applications for Food Safety and Quality Monitoring

    • 1 Edición
    • Arun Sharma + 3 más
    • Inglés
    Nanotechnology Applications for Food Safety and Quality Monitoring brings together nanotechnology science-based research for food safety and quality monitoring. With the advancement in knowledge about behavior of nano-engineered materials in food and its toxicity, the application of nanotechnology is expected to reach unprecedented levels in achieving food safety. Currently, there is no practical resource of nanotechnology as a tool specifically for monitoring safety and quality. This is a practical, concise, applications-based reference that is essential for food industry researchers and scientists to monitor the safety and quality of food to ensure quality food supplies.

  • Principles of Forensic Pathology

    From Investigation to Certification
    • 1 Edición
    • Susan F. Ely + 1 más
    • Inglés
    Principles of Forensic Pathology: From Investigation to Certification offers a conceptual framework and foundational approach to a forensic practice grounded by evidence-based and mechanistic thinking. This book uses a systematic approach to address, explain, and guide the reader through diverse topics relevant to forensic pathologists and medicolegal death investigators. Nineteen chapters provide a comprehensive overview of the field of forensic pathology and discusses central topics such as scene investigation, the pathophysiology of death, death certification, the forensic autopsy, forensic imaging, pediatric forensic pathology, the importance of context, and approaches to frequently encountered medicolegal death circumstances, with mental checklists and suggestions for a consistent and considered approach. Written by forensic professionals, this book is a practical, yet comprehensive compendium for practicing forensic pathologists, coroners, medicolegal death investigators, forensic pathology fellows, pathology residents, medical students interested in forensic pathology, lawyers, and law enforcement professionals.

  • Visceral and Ectopic Fat

    Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease
    • 1 Edición
    • Hildo J. Lamb
    • Inglés
    While the health consequences and mechanisms by which visceral fat causes disease are well-studied, relatively less is known about ectopic fat, its patterns of deposition and its effects on the pathoetiology of type 2 diabetes, atherosclerosis, and cardiovascular disease. Visceral and Ectopic Fat: Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease covers the wealth of literature that has been amassed over the past decade on this topic. This reference brings all the research and clinical data together in one volume and helps clinicians and academic researchers understand more thoroughly the underlying mechanisms and interrelation between fat depots and ectopic fat stores in relation to health and disease. It showcases some of the recent developments in adipose tissue biology, particularly on the impact of interventional strategies - bariatric surgery, liposuction, physical and dietary intervention - of which information is desired among health specialists and policy makers.

  • Viruses and Climate Change

    • 1 Edición
    • Volumen 114
    • Inglés
    Viruses and Climate Change, Volume 114 in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters on carbon-cycle and vector-borne viruses. Chapters in this release cover Viruses in the carbon cycle and the impacts on climate change and Climate change and mosquito-borne virus transmission.

  • Chemical Reactivity in Quantum Mechanics and Information Theory

    • 1 Edición
    • Roman F Nalewajski
    • Inglés
    Chemical Reactivity in Quantum Mechanics and Information Theory introduces a thermodynamic-like description of molecular systems and provides an objective treatment of their fragments. The book formulates adequate entropic tools for probing in chemical terms and the electronic structure of molecules and rationalizing reactivity principles. It covers the information origins of chemical bonds, covalent/ionic composition, trends in molecular stability and reactivity, equilibrium polarizations and charge-transfer reconstructions of reactive complexes, as well as the phase/current promotions of molecular substrates. In addition, the book introduces a precise descriptor of molecular fragments and clarifies mostly intuitive semantics of several chemical concepts. Readers will find a precise and unbiased description of chemical reactivity phenomena in Donor-Acceptor systems in terms of quantum states and generalized concepts of Information/Communic... theories.

  • Osteoarthritis Health Professional Training Manual

    • 1 Edición
    • David J. Hunter + 1 más
    • Inglés
    Osteoarthritis Health Professional Training Manual addresses current gaps in knowledge and the skills and confidence that are necessary to deliver evidence-based OA care that is consistent with international guidelines and for effective translation to clinical practice for health professionals. Written for health care professionals that meet patients with osteoarthritis in the clinic, like GPs, physiotherapists, rheumatologists, orthopedic surgeons, and MDs and PTs in training, medical students and basic researchers on osteoarthritis who want an update on the clinical aspects of OA, this book addresses the urgent need to improve health professional knowledge in managing patients with osteoarthritis.

  • Endocrine Hypertension

    From Basic Science to Clinical Practice
    • 1 Edición
    • Joseph M. Pappachan + 1 más
    • Inglés
    **Selected for 2026 Doody's Core Titles in Endocrinology/Metabo... Disease**Endocrine Hypertension: From Basic Science to Clinical Practice bridges the gap between scientists and practicing clinicians by providing a comprehensive overview on all forms of endocrine hypertension, covering epidemiological aspects, pathophysiology, clinical presentation, laboratory evaluation and practical management aspects of endocrine hypertension. This book is a great resource for endocrinologists, physicians, general practitioners and researchers who are eager to understand the complex facets of endocrine hypertension.Endocri... hypertension is a term used to describe a group of endocrine pathologies that cause an elevation of blood pressure, estimated to account for up to 10% of all hypertension cases. Although common, this clinical condition is often overlooked. Patients with this condition are at risk of late diagnosis, delayed treatment and detrimental health consequences.

  • Understanding Microbial Biofilms

    Fundamentals to Applications
    • 1 Edición
    • Surajit Das + 1 más
    • Inglés
    **Selected for Doody’s Core Titles® 2024 in Microbiology**Unders... Microbial Biofilms: Fundamentals to Applications focuses on the microbial biofilms of different environments. The book provides a comprehensive overview of the fundamental aspects of microbial biofilms, their existence in nature, their significance, and the different clinical and environmental problems associated with them. The book covers both the fundamentals and applications of microbial biofilms, with chapters on the introduction to the microbial community and its architecture, physiology, mechanisms and imaging of biofilms in nature and fungal, algal, and bacillus biofilm control. In addition, the book highlights the molecular and biochemical aspects of bacterial biofilms, providing a compilation of chapters on the bacterial community and communication from different environments. Finally, the book covers recent advancements in various aspects of microbial biofilms including the chapters on their biotechnological applications. All the chapters are written by experts who have been working on different aspects of microbial biofilms.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 121
    • Geoffrey M. Gadd + 1 más
    • Inglés
    Advances in Applied Microbiology, Volume 121 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Unravelling Plant-Microbe Synergy

    • 1 Edición
    • Dinesh Chandra + 1 más
    • Inglés
    Unravelling Plant-Microbe Synergy focuses on agriculturally important microorganisms (AIM’s) that are indigenous to soil and roots of the plant. These microbes contributing to nutrient balance, growth regulators, suppressing pathogens, alleviate stress response, orchestrating immune response and improving crop performance as they are offering sustainable and alternative solutions to the use of chemicals in agriculture. As plant microbe synergy is an enthralling subject, is multidisciplinary in nature, and concerns scientists involved in applied, and environmental microbiology and plant health and plant protection, Unravelling Plant-Microbe Synergy is an ideal resource that emphasizes the current trends of, and probable future of, microbes mediated amelioration of abiotic and biotic stress, agriculture sustainability, induced systemic tolerance and plant health protection. Unravelling Plant-Microbe Synergy discloses the microbial interaction for stress management and provides a better understanding to know the recent mechanisms to cope these environmental stresses. Unravelling Plant-Microbe Synergy bridges the gap in recent advances in the microbes interaction and rhizosphere engineering.

  • Molecular, Cellular, and Metabolic Fundamentals of Human Aging

    • 1 Edición
    • Evandro Fei Fang + 2 más
    • Inglés
    Molecular, Cellular, and Metabolic Fundamentals of Human Aging provides researchers with an overview of the main aging mechanisms and physiology and how they can lead to age-related diseases and conditions. Topics covered include DNA damage and how ineffective repair can lead to cell and tissue aging and decreased functionality, loss of proteostasis, changes to feeding and fasting pathways, mitochondrial dysfunction, the impact of decreased ability of autophagosomes and autophagosomes, cellular senescence, changes to communication molecules, and the impact of stem cell exhaustion. The book also considers the impact of aging within the immune system, the relationship between aging and diseases such as cancers and neurodegenerative conditions, and provides an overview on the dialogue surrounding the topic of aging beyond basic biology.

  • Recent Advances and Future Perspectives of Microbial Metabolites

    Applications in Biomedicine
    • 1 Edición
    • Surajit de Mandal + 4 más
    • Inglés
    Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine sheds new light on various applications of microbial metabolites in the biomedical sector. The purpose of this book is to integrate the latest research advancements on the application of microbial metabolites in the medical industry into a single platform. In 10 chapters, the significance of biomedical applications and future therapeutic applications of microbial metabolites in human health are highlighted. Several chapters are dedicated to the role of microbial metabolites in precision medicine like the impact of the activities of microbial metabolites in antitumor and antidiabetic agents and immunosuppressive activities. It also provides a roadmap for drugs discovery based on antimicrobial products and the effect of microbial metabolites on humans’ health and the immune system. The book finalizes with a chapter on the use of microbial metabolites in OMICS technology. Recent Advances and Future Perspectives of Microbial Metabolites: Applications in Biomedicine targets researchers from both academia and industry, professors, and graduate students from microbiology, molecular biology, biotechnology, and immunology.

  • Oxidative Stress

    Its Mechanisms and Impacts on Human Health and Disease Onset
    • 1 Edición
    • Harold Zeliger
    • Inglés
    Oxidative Stress: Its Impact on Human Health and Disease Onset examines all factors known to elevate oxidative stress (OS) and the mechanism of OS disease causation. Sections cover the causes and prevention of oxidative stress, the types of chemical exposures and environmental factors that precipitate disease, disease hallmarks and biomarkers, disease clusters, disease co-morbidities, free radical attacks at the cellular level, and the Oxidative Stress Index tool, its premise, and how it can be used to identify the primary causes of specific diseases and predict the likelihood of disease onset. With comprehensive coverage of not only the impact of OS due to chemical exposure but also the consequences of environmental factors, this book is a valuable resource for researchers and scientists in toxicology and environmental science, health practitioners, public health professionals, and others who wish to broaden their knowledge on this topic.

  • Epilepsy, An Issue of Neurologic Clinics

    • 1 Edición
    • Volumen 40-4
    • Steven C. Schachter
    • Inglés
    In this issue of Neurologic Clinics, guest editor Dr. Steven C. Schachter brings his considerable expertise to the topic of Epilepsy. Top experts in the field cover key topics such as telemedicine and epilepsy care; wearable technologies and mobile apps in the evaluation and treatment of epilepsy; effects of maternal use of AEDs on child development; sleep and epilepsy; dietary treatments for epilepsy; and more.

  • Potato Production Worldwide

    • 1 Edición
    • Mehmet Emin Calıskan + 2 más
    • Inglés
    Potato is a crop grown on all inhabited continents of the globe. It is included in the top five crops of the world, used as staple food in several countries, and the number of people daily consuming the potato may surpass one billion. Despite the high quantities of seed potato produced worldwide, there are yield gaps due to challenges such as abiotic stresses, pests, climate change and poor production practices. A region-wide critical analysis of yield declining factors can help formulate management strategies that can improve potato yields. Bridging yield gaps in potato will ultimately ensure the role of this crop in securing current and future food security. Potato Production Worldwide presents information on this global crop from its history, morphology, and taxonomy to the growth and development of the potato crop, including the latest strategies in addressing today’s biotic and abiotic challenges. This book identifies the reasons for yield gaps in various potato production regions of the world, as well as presenting the best production practices, pest management strategies and approaches to deal with climate change from the perspective of potato production. Chapters provide important insights into potato production cultures and approaches in the major potato production countries. Potato Production Worldwide will be a valuable resource for researchers, scientists and students seeking a comprehensive view of successful potato production.

  • Lockhart and Wiseman’s Crop Husbandry Including Grassland

    • 10 Edición
    • Alison Samuel + 3 más
    • Inglés
    Lockhart and Wiseman’s Crop Husbandry Including Grassland, Tenth Edition delivers the latest developments in crop varieties, crop protection products and environmental schemes. This new edition reflects the changing world around us, with sections covering the principles of crop production and chapters on plants, climate, soil management, fertilizers, manures, weeds and diseases that threaten farm crops. Other chapters focus on crop husbandry techniques and the integration of sustainability across the board in crop production. This update also includes an additional focus on the principles of plant breeding, seed production and certification considerations necessary for today’s agriculture.

  • Mind Mapping and Artificial Intelligence

    • 1 Edición
    • Jose Maria Guerrero
    • Inglés
    In the near future, we will see an increase in the development and use of all sorts of AI applications. Some of the more promising areas will be Finance, Healthcare, IoT, Manufacturing, Journalism, and Cybersecurity. Many of these applications generate a great amount of complex information. Natural Language Understanding is one of the most clear examples. Traditional ways of visualizing complex information, namely linear text, web pages and hyperlink-based applications, have serious productivity problems. Users need a lot of time to visualize the information and have problems seeing the whole picture of the results. Mind mapping is probably the only way of reducing the problems inherent in these traditional ways of visualizing complex information. Most people have no clear idea about the advantages of mind mapping or the problems created by the traditional ways of visualizing complex information. The goal of Mind Mapping and Artificial Intelligence is to provide readers with an introduction to mind mapping and artificial intelligence, to the problems of using traditional ways of visualizing complex information and as an introduction to mind mapping automation and its integration into Artificial Intelligence applications such as NLU and others. As more applications of Artificial Intelligence are developed in the near future, the need for the improvement of the visualization of the information generated will increase exponentially. Information overload will soon also happen in AI applications. This will diminish the advantages of using AI. Author José Maria Guerrero is a long-time expert in mind mapping and visualization techniques. In this book he also introduces readers to MindManager mind mapping software, which can considerably reduce the problems associated with the interpretation of complex information generated by Artificial Intelligence software.

  • Human Microbiome in Health and Disease - Part B

    • 1 Edición
    • Volumen 192
    • Inglés
    Human Microbiome in Health and Disease, Volume 192, Part B includes chapters surrounding the role of human microbiome in different diseases. Chapters in this comprehensive new volume include The microbiome and communicable diseases, Gut Microbiome and Antimicrobial Resistance in bacterial pathogens, Dysbiosis of human microbiome and infectious disease, Gastrointestinal microbiome in the context of infection in stomach and gastroduodenal diseases, Respiratory tract microbiome and pneumonia, Gut microbiome and neonatal sepsis, Diarrheal disease and gut microbiome, The microbiome and non-communicable diseases, Gut microbiome and inflammatory bowel disease, Gut microbiome and undernutrition, Human microbiome and cardiovascular disease, and much more.

  • Encyclopedia of Cell Biology-

    • 2 Edición
    • Ralph A. Bradshaw + 2 más
    • Inglés
    Encyclopedia of Cell Biology, Second Edition, a Six Volume Set, has established itself as a fundamental reference work, providing broad coverage of the field in four main sections (Molecular, Organizational, Functional, Translational and Pathological Aspects of Cell Biology). This second edition revisits and expands each section, with entries on topics not covered in the first edition, including Crispr. The whole work is updated, providing greater coverage of specialized cell function and translational applications, and putting greater emphasis on these topics in graduate/medical teaching. New overview chapters and subsections provide a simplified cell biology text that can be used by instructors. The new version includes a standard template for each chapter, making the content easier to navigate, as well as inserts and graphics which provide summaries of key points in each chapter.

  • Posttraumatic Epilepsy

    Basic and Clinical Aspects
    • 1 Edición
    • Carrie R. Jonak + 2 más
    • Inglés
    Posttraumatic Epilepsy: Basic and Clinical Aspects provides a synthesized resource on the recent basic and clinical science developments in the field of posttraumatic epilepsy. This book provides a clear understanding of the history of studies and epidemiology of posttraumatic epilepsy after head injury. The book also considers the neuropathology of posttraumatic epilepsy and clinical trials of antiepileptogenic agents evaluated after traumatic brain injury. The book covers the basic science of animal models of traumatic brain injury and the necessary and sufficient changes that must occur to generate epilepsy after head trauma. The authors explore potential mechanisms and novel therapeutic approaches to prevent posttraumatic epilepsy. The book is written for basic and clinical researchers in neuroscience as well as for clinicians treating patients with epilepsy.

  • Athlete Mental Health and Performance Optimization

    The Optimum Performance Program for Sports (TOPPS)
    • 1 Edición
    • Brad Donohue + 1 más
    • Inglés
    Athlete Mental Health and Performance Optimization: The Optimum Performance Program for Sports (TOPPS)introduces TOPPS, which provides structured protocols to assist with recruitment, engagement, screening, assessment and performance optimization. The book presents step-by-step instructional guidelines, real-world case examples, screening and assessment questionnaires, scoring instructions, intervention handouts and worksheets that complement intervention. TOPPS has demonstrated significantly improved relationships with teammates and coaches, decreased substance use and psychiatric symptoms, and decreased factors interfering with sport performance. These results have been sustained in follow-up and has been shown to have improved outcomes regardless of mental health diagnostic severity. The Book's first three chapters introduce performance optimization orientation, theories and evidence supporting TOPPS, general assessment and intervention approaches, psychometrically-val... measures and strategies used to address culture, methods of establishing a culture of optimization and requisite infrastructure within the respective system, and therapeutic style, techniques and implementation strategies. Remaining chapters show how to implement TOPPS.

  • Biochemical Pathways and Environmental Responses in Plants: Part A

    • 1 Edición
    • Volumen 676
    • Inglés
    Biochemical Pathways and Environmental Responses in Plants, Part A, Volume 676 in the Methods in Enzymology series highlights new advances in the field with this new volume presenting interesting chapters on topics such as Structure, function, and engineering of plant polyketide synthases, A sensitive LC-MS/MS assay for enzymatic characterization of methylthioalkylmalat... synthase involved in glucosinolate side-chain elongation, Assaying formate-tetrahydrofo... ligase with monoglutamylated and polyglutamylated substrates using a fluorescence-HPLC based assay, An Approach to Nearest Neighbor Analysis of Pigmented Protein Complexes by Using Chemical Crosslinking in Combination with Mass Spectrometry, and much more. Other chapters cover Biochemical characterization of plant aromatic aminotransferases, Functional Analysis of Phosphoethanolamine N-methyltransferase (PMT) in Plants and Parasites, A structure-guided computational screening approach for predicting plant enzyme-metabolite interactions, Plant metacaspase: an example of microcrystal structure determination and analysis, Biocatalytic system for comparative assessment of functional association of cytochrome P450 monooxygenases with their redox partners, Dirigent Protein Family Function and Structure, and more.

  • Obesity Epidemic and the Environment

    Latin America and the Caribbean Region
    • 1 Edición
    • Matheus Koengkan + 3 más
    • Inglés
    Obesity Epidemic and the Environment: Latin America and the Caribbean Region provides a broad analysis of the macroeconomic impact of the obesity epidemic on environmental degradation in the LAC region. Case studies combine theory and practice to achieve critical conclusions (and subsequent policy implications), providing useful tools for those working on actual health, energy and environmental challenges. Written for researchers, policymakers, international organizations and practitioners in various fields, especially those in public health, health economics, energy and environmental economics and social sciences, this book thoroughly highlights the obesity epidemic in this region. In the LAC region, obesity has become a public health issue. The increase of this problem is related to the economic gains obtained from the process of liberalization and privatization, the increase of foreign investment, and infrastructure investments.

  • Application of Natural Products in SARS-CoV-2

    • 1 Edición
    • Kamal Niaz
    • Inglés
    Application of Natural Products in SARS-CoV-2 examines the potential for natural products to treat COVID-19, bringing together the most recent research. SARS-CoV-2 is a novel disease H54 that is still being researched despite being globally prevalent. There are still few proven treatments, so repurposing existing drugs and treatments is essential. While there have been many articles published on the subject, this book is the first to bring together data and research on the topic. It includes information about molecular mechanism, dosage and safety profiles, and an essential resource for all scientists and researchers working to combat SARS-CoV-2.

  • Sustainable Plant Nutrition

    Molecular Interventions and Advancements for Crop Improvement
    • 1 Edición
    • Tariq Aftab + 1 más
    • Inglés
    Sustainable Plant Nutrition: Molecular Interventions and Advancements for Crop Improvement explores the significant opportunities for sustainable, eco-friendly approaches in plant nutrition and agricultural crop production. The book highlights the various prospects involved in optimizing plant nutrient uptake agriculture and includes chapters representing diverse areas dealing with biotechnology, nanotechnology, molecular biology, proteomics, genomics and metabolomics. This book is an ideal resource for those seeking to ensure a sustainable plant production future. While plants have evolved a set of elaborate mechanisms to cope with nutrient limitations, the traditional supplementation by the application of fertilizers to plant productivity may then lead to overfertilization which can actually reduce plant growth and have adverse effects on the environment. To tackle these issues, a detailed understanding of the responses of plants to nutrients and nutrient deficiency at the physiological, metabolic, transcriptome and epigenetic level is essential.

  • Recent Advances in Aquaculture Microbial Technology

    • 1 Edición
    • Jyothis Mathew + 3 más
    • Inglés
    Recent Advances in Aquaculture Microbial Technology emphasizes various topics on microbiology related technology for aquaculture development and discusses different types of microbiological applications, thus serving as an all-inclusive reference which consolidates microbial technologies adopted in the field. The book covers the history and development of microbial technology in aquaculture as well as aquaculture microbiology, diversity and the role of microbes in aquaculture systems. In addition, it presents the beneficial microbial communities in aquaculture and varying methods employed to study bacterial association in fish, microbes and fish diseases. This resource will help improve research experiments and accomplishments in the area of aqua-culturally relevant microbial technology, making it useful for researchers and scientists in the field.

  • Molecular Nutrition and Mitochondria

    Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals
    • 1 Edición
    • Sergej M. Ostojic
    • Inglés
    Molecular Nutrition and Mitochondria: Metabolic Deficits, Whole-Diet Interventions, and Targeted Nutraceuticals provides a comprehensive examination of molecular aspects of mitochondrial nutrition and how dietary compounds might impact the treatment of mitochondrial dysfunction. Beginning with an overview of the fundamentals of mitochondria physiology and the methods used to evaluate mitochondrial imbalance in clinical practice, the book goes on to outline nutritional shortfalls in mitochondrial dysfunction and highlights the complex intra-organelle milieu affecting interactions between food compounds and mitochondrial co-factors, metabolites, and signaling molecules. Further sections explore the impact of essential nutrients, such as vitamin E, fatty acids, and complex lipids, on mitochondrial biogenesis, as well as non-essential bioactive compounds originating from food that can be evaluated for their mitochondria-modulat... potential, such as mitochondria-targete... small molecule antioxidants, plant-based pigments and organic compounds, nucleotides, non-proteogenic amino acids and derivatives, and mitochondria-specifi... enzyme mimetics from food. Molecular Nutrition and Mitochondria covers the key impacts of nutrition on mitochondria, and is the ideal reference for researchers, students and clinicians looking to develop an in-depth understanding of how dietary compounds can prevent and treat disorders associated with mitochondrial dysfunction.

  • Insect Resistance Management

    Biology, Economics, and Prediction
    • 3 Edición
    • David W. Onstad + 1 más
    • Inglés
    The third edition of Insect Resistance Management: Biology, Economics, and Prediction expands coverage by including three new chapters on African agriculture, genetic control of pests, and fitness costs of resistance. All remaining chapters have been updated to cover key scientific findings published since 2013. The coauthors have expertise in evolutionary biology, ecology, economics, epizootiology, statistics, modeling, IPM, and genetics. The original themes demonstrating the importance of economics, IPM, pest behavior, and the behavior of humans implementing insect resistance management (IRM) are still relevant. Entomologists and others developing experiments, models, regulations, or public policy will benefit from this book that avoids reliance on dogma by analyzing and synthesizing knowledge about a wide variety of species, landscapes, and stakeholder problems.

  • Patient-Reported Outcomes in Endocrine Diseases, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 51-4
    • Eliza B. Geer
    • Inglés
    In this issue of Endocrinology and Metabolism Clinics, guest editor Eliza B. Geer brings her considerable expertise to the topic of Patient-Reported Outcomes in Endocrine Diseases.

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