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Elsevier

Libros en Ciencias de la Vida

  • CDK4/6 inhibitors in Breast Cancer Therapy

    • 1 Edición
    • Pankaj Kumar Singh + 3 más
    • Inglés
    CDK4/6 inhibitors in Breast Cancer Therapy examines the pivotal role of CDK4/6 inhibition in treating hormone receptor-positive (HR+)/HER2-negative advanced breast cancer. The book highlights FDA-approved applications of these inhibitors alongside endocrine therapy and explores ongoing research into their potential as neoadjuvant treatments. It provides insights into the drug discovery and development of CDK4/6 inhibitors, covering their molecular mechanisms, pharmacology, and clinical applications. Chapters address their use in mono and adjuvant therapies, as well as challenges in targeting, while also discussing market potential and post-marketing safety issues.This book is a valuable resource for researchers and academics, enhancing understanding of CDK4/6 inhibitors' chemistry and therapeutic implications. By presenting detailed information on clinical trials and market formulations, it equips the audience with essential knowledge to navigate the complexities of targeted breast cancer therapies and contributes to advancing research in this critical area.

  • Microbial Technologies for Sustainable Waste Management

    • 1 Edición
    • Rajneesh Kumar + 2 más
    • Inglés
    Microbial Technologies for Sustainable Waste Management explores advanced waste management through microbial processes. The book investigates the current limitations of traditional waste treatment and the potential for microbial cell factories in bringing innovative solutions to this field. Beginning with an introduction to the role of microbes in waste management, it examines global case studies demonstrating success stories in microbial waste treatment and microbial innovations for biotechnological applications in waste conversion. Concluding chapters focus on microbial pathways for anaerobic digestion, hydrolysis, and fermentation, and microbial technologies for industrial applications such as wastewater treatment and the biofuel industry.Additionall... the book considers microbial remediation of hazardous and toxic waste, microbial fuel cells, and strategies for plastic waste degradation. Emerging technologies, such as AI integration, microbial nanotechnology, and engineered microbes are discussed, along with their environmental impacts and potential for scaling up to commercial applications.

  • Progress in Motor Control

    Crossroads between Neurophysiology and Applications
    • 1 Edición
    • Mark L. Latash + 4 más
    • Inglés
    "Progress in Motor Control: Crossroads between Neurophysiology and Applications" offers an in-depth look at the evolving field of motor control, synthesizing the latest research. This volume explores the complex roles of the central nervous system in movement, featuring contributions from leading experts who use approaches ranging from basic physical principles to advanced control theory. It addresses applied aspects of motor control, focusing on recovery strategies for functional movements in patients with spinal cord injuries, subcortical disorders, and strokes. Organized into five sections, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including topics like neural population dynamics and vestibulospinal reflexes. The final sections highlight strategies for improving recovery after neurological events. This resource bridges foundational research and clinical application, making it invaluable for researchers, clinicians, and students in motor control, neuroscience and rehabilitation.Divid... into five comprehensive parts, the book covers theoretical advances, neurophysiological mechanisms, motor learning, neural plasticity, and motor disorders, including essential topics like neural population dynamics and the dual role of vestibulospinal reflexes. Final sections highlight practical strategies for improving recovery outcomes following neurological events.

  • Genome Damage

    Repair and Adaptation Across Life
    • 1 Edición
    • Vinod K. Kannaujiya + 2 más
    • Inglés
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.

  • Applying Artificial Intelligence to Computational Biology and Medical Informatics

    • 1 Edición
    • Mohammad Sufian Badar
    • Inglés
    Applying Artificial Intelligence to Computational Biology and Medical Informatics explores the transformative role of AI and machine learning in modern biomedical research and healthcare. The book covers foundational concepts in AI/ML, computational biology, and medical informatics, followed by in-depth chapters on medical imaging, network biology, chemoinformatics, and public health. Other sections address ethical and societal implications, interpretable AI, and real-world case studies, making complex topics accessible through clear language and structured content. Designed for early-career researchers, students, and professionals without prior expertise in computer science or health sciences, this book provides a progressive learning path from basic to intermediate levels.Readers benefit from practical examples, online resources, and a coherent chapter structure that supports both academic study and applied research.

  • Neuroscience for Sleep Medicine, Part C

    • 1 Edición
    • Volumen 305
    • Inglés
    Neuroscience for Sleep Medicine, Part C offers a comprehensive and forward-looking integration of cutting-edge neuroscience with clinical sleep science, bridging molecular, circuit-level, and behavioral perspectives on sleep and its disorders. The volume explores neural mechanisms, cognitive-affective processes, and emerging neurotechnologies that shape both normal sleep and pathological conditions. With a strong translational emphasis, it advances a bench-to-bedside framework that informs precision diagnostics, innovative therapeutics, and future directions in sleep medicine and neuropsychiatry.

  • Plant Polyphenols in the Food and Cosmetic Industries

    Extraction and Applications
    • 1 Edición
    • José Manuel Lorenzo
    • Inglés
    Plant Polyphenols in the Food and Cosmetic Industries: Extraction and Applications explores the use of polyphenols in food and cosmetics. Broken into three parts, the book begins with coverage of extraction and purification processes before delving into specific food and cosmetic applications. Plant Polyphenols in the Food and Cosmetic Industries: Extraction and Applications provides nutrition researchers, food scientists, and plant scientists an opportunity to better understand the use of polyphenols in their industries.

  • The Honey Bee and Climate Change

    • 1 Edición
    • Gloria DeGrandi-Hoffman
    • Inglés
    A honey bee colony is a community of interacting organisms continually adjusting their behaviors, both individually and collectively, in response to even the subtlest changes in the environment. It’s only logical then, that the more significant changes and stressors due to climate change will push the colony to its limits, disrupting the delicate balance of the hive and threatening the survival of the colony. Honey Bees and Climate Change is the first and only book to examine the responses of honey bees to climate change and the threat it poses to their ability to thrive and survive. Drawing on systems science and the central theme that all outcomes are products of an interconnected system, the book will address how climate change is affecting honey bee nutrition, growth, and overwinter survival, which in turn threaten commercial beekeeping and crop production. Impacts on other pollinators will be touched on as well. Finally, potential mitigating strategies, key areas of action, and the future outlook will be covered.Written by a leading scientist with over 40 years of experience studying honey bee physiology, nutrition, colony survival, and the impact of climate change on the colony, Honey Bees and Climate Change is crucial reading for students and researchers studying honey bees, especially those with an interest in the impacts of climate change on pollinators. The inclusion of key terms and definitions as well as case studies make this work an excellent supplementary text for courses on honey bee biology, apiculture, pollinator conservation, or climate change ecology.

  • Neurobiology of Obsessive-Compulsive Disorder

    • 1 Edición
    • Eric A. Storch + 2 más
    • Inglés
    Neurobiology of Obsessive-Compulsive Disorder provides a comprehensive review of obsessive-compulsive disorder through a neurobiological lens, offering invaluable insights for researchers and clinicians alike. The book begins with a comprehensive introduction to OCD, detailing its definition, historical perspectives, prevalence, and symptomatology, alongside its comorbidities and associated disorders. Delving into the genetic and familial aspects, the book examines genetic predispositions, heritability, and significant genome-wide association studies. In addition, it addresses neuropsychological findings, cognitive dysfunctions, and implications for treatment, alongside neurodevelopmental factors, including early life stress, immune system dysregulation, and environmental risk factors.Special attention is given to PANDAS/PANS as mechanisms of OCD pathogenesis and the insights gained from animal models. Subsequent chapters cover diagnosis, pharmacological treatments, and a range of psychotherapeutic and behavioral interventions, including CBT, ERP, and ACT, as well as neuromodulation techniques. Finally, the book presents neurobiology-informe... treatment approaches, personalized medicine, and integrative strategies, concluding with discussions on current challenges, ethical considerations, and future research directions.

  • Intelligent Gene Editing in Plants

    The Convergence of AI and CRISPR
    • 1 Edición
    • Aftab Ahmad + 3 más
    • Inglés
    Intelligent Gene Editing in Plants analyzes how AI-enabled design and CRISPR-based genome engineering are reshaping plant genetics, with a clear functional focus on delivering durable gains in crop productivity, stress tolerance, and nutritional quality.The work unfolds in three parts: [i] a foundational survey of genome-editing technologies and the evolving role of AI in precise trait modifications and outcome prediction; [ii] a thorough exploration of applications and synergies, including AI-assisted gRNA optimization, off-target mitigation, regulatory-network analysis, and trait enhancement for disease resistance and climate resilience; and [iii] an emerging-horizons section on cis-regulatory edits, omics integration, synthetic biology, and next-generation editing.Throughout, the volume interweaves practical experiences, cutting-edge methodologies, and case studies, alongside discussions of biosafety, ethical concerns, governance, and public perception, providing a holistic, decision-ready resource for students, researchers, practitioners, and regulatory authorities to navigate the opportunities and responsibilities of plant gene editing, with significant implications for sustainable agriculture and global food security.

  • Politics, Practice, and Policy

    How to Get Things Done in Food and Nutrition, 10 Case Studies
    • 1 Edición
    • Eileen Kennedy
    • Inglés
    Food and Nutrition Policy: 10 Case Studies for Developing Effective Policies and Programs explains how policy compromises are reached and then changed over time as new information becomes available. Derived from the authors’ experiences while serving as a political appointee in the federal government, participating in international committees and boards, and from materials from a graduate course which she teaches on global food and nutrition policy at Tufts University, the 10 case studies presented in this book provide real world learning examples on how contentious issues are resolved in the political process.While each of the ten chapters focuses on a specific topic, the book showcases an overriding theme of food and health justice, equity, and empowerment. Readers will deduce key factors to examine pivotal policy decisions while the author dissects polarizing topics such as examining the successes and failures of dietary guidelines, front label packaging approaches, implications of expanding personalized nutrition, the obesity epidemic and the role of GMO’s in agricultural production, and more.

  • Hormones in Neuroscience

    The Thyroid Gland and Thyroid Hormones
    • 1 Edición
    • Colin R. Martin + 3 más
    • Inglés
    Hormones in Neuroscience: The Thyroid Gland and Thyroid Hormones explores the thyroid gland and thyroid hormones in-depth, presenting the latest research in neuroendocrinology and how it applies to translational and multidisciplinary methods. Covering different domains that bridge the physiological and medical divides between hormones and neurological tissues, this book will be a valuable resource for neuroendocrinologist... neuroscientists, pathologists, research scientists, and molecular or cellular biochemists in the field of hormone neuroscience.

  • Starches in Smart Packaging

    • 1 Edición
    • Swarup Roy + 1 más
    • Inglés
    Starches in Smart Packaging explores the innovative use of biodegradable, starch-based polymers in developing sustainable packaging solutions. Derived from natural resources such as maize, rice, and tubers, starch is a non-toxic, eco-friendly material with great potential to replace conventional plastics. This book addresses the growing need for environmentally responsible packaging by covering research from laboratory studies to industrial applications, focusing on smart packaging for food preservation, quality monitoring, and active packaging functionalities. Content includes discussions on starch extraction processes, fabrication techniques, and methods to enhance properties like barrier, thermal, and mechanical performance.It also examines the incorporation of bioactives, nanomaterials, natural colorants, and cross-linkers to create advanced packaging materials. Finally, the book highlights applications in extending shelf life, monitoring food freshness, and ensuring safety, alongside considerations for large-scale production, biodegradability, and sustainability. Regulatory frameworks, consumer acceptance, and future challenges in the field round out the content.

  • Mineral Nutrients to Mitigate Abiotic Stress in Crops

    • 1 Edición
    • Azamal Husen
    • Inglés
    Mineral Nutrients to Mitigate Abiotic Stress in Crops examines the physiological and biochemical dynamics that govern how plants endure increasingly unpredictable growing conditions. Sections outline the fundamental principles that shape a crop’s capacity to acquire, distribute, and utilize nutrients, and then consider how these processes influence its survival and productivity when confronting drought, salinity, heat, or nutrient-induced stress. Across chapters, contributors show how nutrient availability guides defense mechanisms—from maintaining cellular stability and enzymatic function to modulating antioxidant potential, osmotic adjustment, and stress-related signaling—and how intensifying environmental pressures reorder metabolic priorities, redirect root behavior, and reallocate resources at the whole-plant level.Building on this foundation and proceeding in an intentionally structured sequence, the book integrates applied approaches, encompassing soil and fertilizer systems, nutrient biofortification, and the breeding of nutrient-efficient cultivars. By integrating established science with emerging insights, it delivers a coherent, forward-looking framework for interpreting plant resilience, and for implementing adaptive strategies that underpin effective responses in diverse cultivation contexts. The book strategically equips researchers and practitioners with what they need to navigate the increasingly complex challenges facing modern agriculture.

  • Insights for Researchers and Clinicians to Navigating Kidney Stone Surgery

    A Comparative Narrative of Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Kidney Stones
    • 1 Edición
    • Oktay Ozman + 1 más
    • Inglés
    Insights for Researchers and Clinicians to Navigating Kidney Stone Surgery: A Comparative Narrative of Percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery for Kidney Stones is the ultimate resource for healthcare professionals seeking to excel in the field of kidney stone surgery. The book provides a comparative history of RIRS and PCNL, exploring their evolution from early attempts at endoscopic stone removal to the development of flexible ureteroscopy and technique refinement. It covers instrumentation, including access sheaths, ureteroscopes, energy sources, and fluoroscopy. Patient selection criteria, anesthesia techniques, and intraoperative monitoring are thoroughly examined.The book offers detailed guidance on kidney access, including transureteral and percutaneous approaches, and discusses fragmentation and stone retrieval methods, comparing their efficacy and outcomes. Complications, management strategies, postoperative care, and long-term outcomes assessment are extensively discussed, ensuring a comprehensive understanding of patient care. With its comprehensive coverage and contributions from renowned experts, the book equips healthcare professionals with the knowledge and skills needed to excel in the rapidly evolving field of minimally invasive kidney stone management.

  • Smart Hospital Anatomy with Advanced Sensors

    Innovations in Patient Care
    • 1 Edición
    • Amit Kumar Tyagi + 1 más
    • Inglés
    Smart Hospital Technology with Advanced Sensors: Innovations in Patient Care explores the transformative role of advanced sensor systems in modern healthcare environments. This book presents a comprehensive overview of smart hospital technologies, emphasizing the integration of AI, IoT, and automation to enhance patient care and hospital operations. Topics covered include wearable and implantable sensors, AI-driven diagnostics, robotic surgery, smart ICUs, and cybersecurity in healthcare. It also addresses emerging trends such as blockchain for medical data, ethical AI, and the convergence of smart hospitals with smart cities. Content is supported by global case studies and expert contributions.Design... for students, researchers, and academics in bioinformatics, this book offers foundational knowledge, current applications, and future directions in digital healthcare. It serves as a valuable resource for understanding the challenges and opportunities in building intelligent, data-driven hospital systems that improve outcomes and redefine patient experiences.

  • Hormones in Neuroscience

    The Pancreas and Pancreatic Hormones
    • 1 Edición
    • Victor R. Preedy + 3 más
    • Inglés
    Hormones in Neuroscience: The Pancreas and Pancreatic Hormones explores the latest research in neuroendocrinology in relation to the pancreas and pancreatic hormones. This volume aims to cover the deficiencies in existing literature on the link between hormones and neurological tissues. This book offers a translational context and seeks to address the behavioral consequences of altered endocrine gland pathology while also addressing causative and modulating influences.

  • Carbon Incentives, Plans, and Policies in Agriculture

    • 1 Edición
    • Ram Swaroop Meena + 3 más
    • Inglés
    Economic incentives intended to catalyze environmentally responsible behavior have assumed a central role in confronting climate change, food insecurity, and natural resource degradation. Notwithstanding their promise, many programs underperform owing to methodological gaps, limited transparency, and insufficient regulatory oversight. Carbon Incentives, Plans, and Policies in Agriculture undertakes a critical appraisal of these constraints and advances evidence‑based propositions for strengthening carbon credit mechanisms across agricultural systems and value chains.The volume assembles a globally diverse authorship to synthesize emergent strategies and forward trajectories in carbon financing and monetization, green accounting, ecological and environmental economics, and carbon credit trading, while situating these within the broader sustainability imperatives of agroecosystems. Distinctive emphasis is placed on measurement and methodological rigor, including quantification protocols, MRV frameworks, and domain‑specific estimation approaches for soils, croplands, grasslands, and agroforestry, together with field-level interventions (e.g., energy and water use efficiency, best management practices, and green manuring) and technological enablement (notably, AI-supported assessment). Integrating scientific, policy, and economic perspectives, this book furnishes a conceptual and operational foundation for scholars, researchers, industry practitioners, and policymakers seeking to design effective, transparent, and equitable governance and planning protocols for a low‑carbon agricultural transition.

  • Meat Preservation and Packaging Techniques

    • 1 Edición
    • Lin Lin
    • Inglés
    Meat Preservation and Packaging Techniques covers a range of conventional and state-of-the-art techniques for preservation of meat and meat products to reduce spoilage and waste. Packaging, which plays a key role in preservation, is covered in-depth, including novel intelligent meat packaging materials, such as biopolymer-based edible coating and films. This interdisciplinary work will cover food quality assurance, safety, shelf-life extension, nanotechnologies, nano and biomaterials, and more. Written and edited by experts at the forefront of this field and its technology, this book is a key resource for researchers in both industry and academic settings.

  • Model Validation and Uncertainty Quantification in Biomechanics

    From Soft Biological Tissue to Blood Flow
    • 1 Edición
    • Gerhard A. Holzapfel + 2 más
    • Inglés
    Model Validation and Uncertainty Quantification in Biomechanics: From Soft Biological Tissue to Blood Flow provides a comprehensive overview of the latest technology in biomechanical modeling and analysis. Part I presents the foundational principles of modeling primary biomechanical systems, including the intricate workings of the cardiovascular system. This section also provides invaluable insights into essential topics such as sensitivity analysis, uncertainty quantification, machine learning, and surrogate modeling. In Part 2, the book transitions into an in-depth examination of the current state-of-the-art in model validation techniques across a diverse array of biomechanical disciplines, including the latest advancements and best practices. Part 3 introduces current and innovative approaches for quantifying uncertainties inherent in biomechanical modeling. Chapters range from established methodologies to emerging techniques, providing a comprehensive overview of the various strategies employed in addressing uncertainty in biomechanical studies. Finally, in Part 4, the book concludes with a focus on cutting-edge methods, specifically spotlighting the utilization of machine learning and surrogate modeling for both model validation and uncertainty quantification. Through real-world applications and case studies, this book provides an in-depth understanding of how these advanced techniques are reshaping the landscape of biomechanics research.

  • Metabolic Memory

    Past, Present and Future Implications
    • 1 Edición
    • Jeena Gupta
    • Inglés
    Metabolic Memory: Past, Present and Future Implications delves into the emerging concept of metabolic memory, exploring how our body's metabolic processes retain a 'memory' of past experiences and how this impacts our current and future health. Drawing on the latest scientific research this book aims to bridge the gap between complex scientific concepts and their practical implications for everyday health and wellness. Metabolic memory has profound implications for understanding chronic diseases, particularly diabetes, cardiovascular diseases, and obesity. Despite its significance, there is a lack of comprehensive resource that make this information accessible to both professionals and the general public. This book fills that gap, providing a detailed yet understandable exploration of how past metabolic states influence present and future health outcomes.

  • Nanophytomedicine

    Harnessing Phytochemicals for Advanced Therapeutics
    • 1 Edición
    • Ali Zarrabi + 2 más
    • Inglés
    Nanophytomedicine: Harnessing Phytochemicals for Advanced Therapeutics explores the integration of phytochemicals and nanotechnology to develop advanced therapeutic solutions. The book offers an extensive overview of phytochemicals, explaining their sources, extraction methods, classifications, and applications in medicine. This emerging field aims to utilize the natural properties of phytochemicals to create innovative treatments for various diseases, with a particular focus on hard-to-treat conditions such as cancer. By combining plant-derived compounds with nanomaterials, researchers are unlocking new potential in precision medicine, seeking to enhance the efficacy of treatments while minimizing side effects and improving patient outcomes.In 18 comprehensive chapters, the book delves into the therapeutic properties of phytochemicals, such as their antioxidant, antifungal, and anti-inflammatory effects. It highlights the role of these compounds in combating diseases including cancer, neurological disorders, diabetes, and cardiovascular diseases. The use of nano drug delivery systems is emphasized, showcasing how these technologies can improve the delivery and effectiveness of phytochemicals.

  • Medical and Health Genomics of South Asia

    • 1 Edición
    • Dhavendra Kumar + 1 más
    • Inglés
    Medical and Health Genomics of South Asia, a new volume in the Genomic and Precision Medicine in Clinical Practice series, offers a thorough discussion of medical genomics as applied across South Asian nations, from India to Pakistan, Bangladesh, Sri Lanka, and Nepal, as well as in South Asian populations abroad. Here, global chapter authors consider genomic variation and the population heterogeneity of genetic, infectious, and lifestyle diseases in South Asia, along with successful modes of population health management for these inherited disorders and other applications of clinical genomics for improved individual health in the region. Adopting an applied approach, this book first reviews basic genomic models and population study formats, as well as the anthropological and genetic history of South Asia. The following sections examine genomic epidemiology and population health in the South Asian context; examples of genomic medicine's use in combating major health challenges in the region; genomic healthcare infrastructure; and related social, ethical, legal, and economic aspects central to impactful genomic medicine.

  • Smart Aquaponic Farming

    An Intelligent Production System for Aquaponics
    • 1 Edición
    • Daoliang Li
    • Inglés
    Smart Aquaponic Farming: An Intelligent Production System for Aquaponics describes the aquaponics AI factory, an ecologically efficient and sustainable multitrophic production model. While traditional aquaculture systems produce farming waste with environmental and food safety implications, the aquaponics model offers a circular organic production method that recycles and reuses aquatic waste to expand the ecological planting scene. Given recent developments in intelligent sensing, information processing, and agricultural equipment technologies, this book provides a much-needed technical guide for industry scientists and technicians. Written by leading experts in aquaculture biosystems engineering, this book reviews technology assembly, system realization, and industrial development of intelligent aquaponics AI factory models. Early chapters introduce the concept of AI factory infrastructure before exploring recirculating aquaculture systems, hydroponic planting systems, and various control systems to maintain air quality, water quality, and fish nutrition. Concluding chapters discuss AI factory system integration, sustainability evaluation, and global case studies of proof-of-concept systems. Smart Aquaponic Farming provides in-depth conceptual analyses, technical overviews, and case presentations to demonstrate the characteristics, advantages, and significance of industrial scale-up for aquaponics. It bridges the gap in disseminated knowledge on analysis, design, and implementation of aquaponics AI factories, making it an indispensable resource for aquaponics producers, technicians, industry scientists, and academics alike.

  • Navigating Tuberculosis

    Insights into Host-Pathogen Protein Interactions
    • 1 Edición
    • Mohammad Shariq + 2 más
    • Inglés
    Navigating Tuberculosis: Insights into Host-Pathogen Protein Interactions, the latest release in the Foundations and Frontiers in Enzymology series, explores the interactions between host proteins and the tuberculosis pathogen, Mycobacterium tuberculosis (M. tb), emphasizing their roles in virulence and pathogenesis. The book delves into mechanistic insights, focusing on their roles in modulating innate and adaptive immunity and understanding TB pathomechanisms by elucidating the interplay between host defenses and M. tb infection. It provides a foundation for developing targeted mitigation strategies and discusses key regulatory pathways and protein factors involved in host-pathogen interactions, informing the design and implementation of innovative approaches to combat TB.This comprehensive volume aims to advance knowledge and strategies to combat tuberculosis, aligning with the World Health Organization's goal of eradicating TB by 2035 by addressing the need for up-to-date information on host-pathogen interactions in tuberculosis and incorporating the latest research findings and advancements. It highlights emerging therapeutic targets among host and TB pathogen proteins and integrates multidisciplinary approaches from microbiology, immunology, and molecular biology, offering a holistic perspective on TB pathophysiology. Researchers will find detailed discussions on key host proteins involved in tuberculosis pathogenesis, the molecular tactics employed by M. tb to subvert host defenses, and host-mediated inhibition strategies targeting M. tb.

  • Harnessing Plant-Stimulating Molecules

    Innovations in Stress Biology and Crop Resilience
    • 1 Edición
    • M. Iqbal R. Khan + 1 más
    • Inglés
    Harnessing Plant-Stimulating Molecules serves as an authoritative reference on the multifaceted molecular regulators and biotechnological innovations underpinning plant resilience to environmental stressors. This volume delivers an exhaustive treatment of diverse classes of signaling entities—including phytohormones, secondary messengers, secondary messengers, reactive oxygen and nitrogen species, and heterotrimeric G proteins—elucidating their roles in complex stress adaptation pathways.In addition to molecular and biochemical foundations, this book explores advanced methodologies such as nanoparticle-facilit... metabolic modulation, RNA interference, and gene-editing strategies aimed at optimizing nutrient utilization. It also highlights the emerging significance of biostimulants in modulating plant–microbe interactions and interplant signaling networks. Detailed discussions on systemic signaling mediated by mobile molecules and photoreceptor-mediat... photomorphogenic responses further enrich the scope.By integrating cutting-edge approaches, particularly CRISPR–Cas systems, with computational modeling for simulating metabolic networks, the volume facilitates accelerated crop improvement strategies essential for addressing contemporary challenges in food security and agroecosystem sustainability.Desig... as an indispensable resource for researchers, advanced graduate students, and industry professionals, Harnessing Plant-Stimulating Molecules bridges fundamental plant molecular biology with translational biotechnology, fostering the development of resilient, high-performance crops adapted to the challenges of a changing climate.

  • Pharmacological Approaches in Cancer Treatment

    A Comprehensive Guide
    • 1 Edición
    • Sadhna Aggarwal + 1 más
    • Inglés
    Pharmacological Approaches in Cancer Treatment: A Comprehensive Guide presents an in-depth exploration of pharmacological approaches utilized in cancer treatment. The book's overarching theme revolves around understanding the intricate mechanisms and applications of various therapies, ranging from targeted treatments to immunotherapies. Through examination and analysis, the content sheds light on emerging trends and breakthroughs in the field, providing a comprehensive overview of cancer pharmacology. Sections target therapies, chemotherapy agents, immunotherapy, personalized medicine, combination therapies, drug resistance, novel drug delivery systems, palliative care in oncology, adverse effects of cancer pharmacotherapy, and preclinical studies.Each chapter provides the nuances of its respective subject matter, providing readers with a thorough understanding of the scientific underpinnings and practical applications of cancer pharmacology. Designed to cater to both oncology professionals and patients, this book serves as a valuable resource for enhancing understanding and informing treatment decisions.

  • Contemporary Research Methods in Pharmacy and Health Services - Volume 2

    • 1 Edición
    • Aleda M. H. Chen + 5 más
    • Inglés
    Contemporary Research Methods in Pharmacy and Health Services, Volume Two is an essential resource for researchers and practitioners in the field of pharmaceutical science. Building on the groundbreaking work published in the esteemed journals Research in Social and Administrative Pharmacy (RSAP) and Exploratory Research in Clinical and Social Pharmacy (ERCSP), this volume addresses the critical need for comprehensive and structured methodologies in evaluating and implementing pharmacy services. By transforming selected articles into fully developed chapters, the book enriches the discourse surrounding contemporary research methods, making it an invaluable tool for advancing knowledge and practice.The volume features a diverse array of chapters that cover a wide range of topics, including the use of the Consolidated Framework for Implementation Research (CFIR) to evaluate telepharmacy services for outpatient cancer patients, the translation and validation of adherence measurement tools, and the application of network analysis in health code systems. Other notable contributions explore innovative strategies for improving clinical pharmacy services, conducting scoping reviews in pharmacy education, and employing mixed-methods approaches to enhance medication counseling.

  • Emotional Artificial Intelligence

    Practical Challenges and Applications
    • 1 Edición
    • Rajesh Kumar Dhanaraj + 4 más
    • Inglés
    Emotional Artificial Intelligence: Practical Challenges and Applications explores the intersection of artificial intelligence and human emotions, challenging the myth that AI will replace humans. Instead, it emphasizes how emotional AI can enhance collaboration, improving efficiency across fields like healthcare, transportation, and space exploration. The book explores foundational theories such as Goleman’s emotional model and Ekman’s emotion theory, discussing methodologies for understanding human emotions through natural language processing and the ethical implications of AI in decision-making. It showcases real-world applications, from virtual nurses to emotion-aware driving systems, illustrating how these technologies can improve daily interactions and outcomes.This essential resource equips researchers, practitioners, and policymakers with practical insights for integrating emotional AI into diverse domains. By addressing the complexities of human emotion recognition and ethical frameworks, it provides a forward-looking perspective on enhancing collaboration between humans and AI, ultimately driving improved productivity and efficiency.

  • BioMEMS Devices

    • 1 Edición
    • Azrul Azlan Hamzah + 2 más
    • Inglés
    BioMEMS Devices covers the fundamentals of bioMEMS and discusses how MEMS are implemented into biomedical devices. The book discusses the most up-to-date technologies, including the various types of electrochemical, optical, and mechanical MEMS sensors. Other topics include bio cell and particle separation and filtration using microfluidic platform such as dielectrophoresis (DEP) and microfilters. MEMS devices for drug mixing, pumping and transdermal drug delivery using microneedles and micropumps are also discussed, along with recent advances in point-of-care diagnostics and MEMS in medical implantsThe book concludes with a discussion on integration of bioMEMS system with IoT, medical practitioners’ adaptation of the devices, market penetration, emerging technologies, and future outlooks.

  • The Immunology of Horses and Donkeys

    • 1 Edición
    • Ian R. Tizard
    • Inglés
    The Immunology of Horses and Donkeys offers a comprehensive overview of the immune systems of equids, bridging a critical gap by combining current research with foundational concepts and emphasizing both mechanisms and practical applications. The book covers immune development, disease resistance, vaccination, and immune disorders, supporting improved health management in horses and donkeys. Organized logically, it begins with the evolutionary history and domestication of equids and then explores immune ontogeny, innate and adaptive responses, and lymphoid tissue structure. Chapters detail the major histocompatibility complex, cytokine signaling, antigen-presenting cells, and mucosal immunity.Additional sections address the microbiota, vaccine strategies, and immune responses to bacterial, viral, and parasitic infections, providing a holistic view of equine immune health. Users will find content that advances understanding in immunology, biomedical research, and veterinary medicine, supporting the development of better diagnostics, vaccines, and therapies. The book's clear, thorough approach benefits both scientific discovery and clinical application, ultimately improving equine health and informing broader mammalian immunology studies.

  • Aquaculture with Artificial Intelligence

    Emerging Technologies for Sustainable Industry Development
    • 1 Edición
    • Baskaralingam Vaseeharan + 3 más
    • Inglés
    Aquaculture with Artificial Intelligence: Emerging Technologies for Sustainable Industry Development will play in aquaculture and aquaculture-adjacent sectors in the coming years. The aquaculture industry faces various challenges, including environmental concerns, disease management, and resource optimization, and integrating AI into aquaculture practices can improve industry efficiency, sustainability, and overall productivity. This book explores how AI technologies such as machine learning for predictive analytics, computer vision for monitoring aquatic environments, and robotics for automated tasks can streamline various aspects of aquaculture requiring monitoring, management, and decision-making. Aquaculture with Artificial Intelligence: Smart Aquaculture is co-authored by a diverse team of experts bridging disciplines in aquaculture, aquatic immunology, biotechnology, and artificial intelligence. Early chapters provide a thorough introduction to the aquaculture industry to provide critical context for all audiences. Central chapters explore machine learning, bioimaging, drone technology, bioengineering, OMICs technologies, big data, and other AI technologies emerging in aquaculture. Global case studies highlight the practical applications of AI to various aspects of aquaculture operations, including automated feeding, water quality monitoring, disease protection, and precision aquaculture. The book concludes with a look to the future of the industry, research gaps, and opportunities for continued research. This is an essential read for aquaculturists, environmental scientists, data scientists, and roboticists interested in the intersection of aquaculture and AI.

  • Advanced Insights into Acute Pancreatitis

    Integrating Research, Diagnosis, and Pathophysiology for Enhanced Clinical Strategies
    • 1 Edición
    • Hiroyuki Tomita + 1 más
    • Inglés
    Advanced Insights into Acute Pancreatitis: Integrating Research, Diagnosis, and Pathophysiology for Enhanced Clinical Strategies offers a comprehensive exploration of acute pancreatitis, merging cutting-edge research with clinical practices. This essential resource equips medical professionals with the latest findings on pathophysiological mechanisms, diagnostic criteria, and treatment strategies, including advancements in intensive care management, fluid resuscitation, nutrition, and surgical interventions. The book covers critical topics such as the epidemiology of pancreatitis, diagnostic criteria, radiological assessments, and the management of complications. It provides in-depth insights into pharmacotherapy, endoscopic interventions, and minimally-invasive surgical approaches, ensuring that readers are well-informed about best practices and innovations in the field.This book serves a diverse audience, including intensivists, internists, radiologists, pathologists, and basic research physicians. It is an invaluable tool for clinicians seeking to enhance their understanding of acute pancreatitis and improve patient outcomes, while also offering researchers the most current information to inform their studies. Whether you are treating patients or advancing research, this book is a vital addition to your library, bridging the gap between clinical practice and scientific inquiry in the management of acute pancreatitis.

  • Geomicrobiology of Río Tinto

    A Terrestrial Mars Analogue
    • 1 Edición
    • Ricardo Amils
    • Inglés
    Geomicrobiology of Río Tinto: A Terrestrial Mars Analogue provides the most detailed biological and geological characterizations of one of Earth's best terrestrial Mars analogues. The acidic waters of Río Tinto and the high metal content of its sediments have given rise to a unique biodiversity. Understanding the geochemical and mineralogical conditions that have shaped the evolution of these extremophiles is essential to guiding the selection of sites for meaningful missions to Mars. Edited by a renowned astrobiologist with contributions from global experts with applied experience in Mars exploration missions, this book is systematically structured for a wide audience. Sections delve into the physical characteristics and biological diversity of Río Tinto, its suitability as a terrestrial Mars analogue, and the fundamentals and applications of geomicrobiology. Geomicrobiology of Río Tinto: A Terrestrial Mars Analogue provides its interdisciplinary audiences with the fundamentals to understand the paleontological record of the system, the diversity existing in its water column, the biological activities responsible for its extreme conditions, and their biotechnological applications and relevance to future exploration missions to the red planet. This is an essential read for astrobiologists, aquatic biologists, geomicrobiologists, paleontologists, and biotechnologists alike.

  • Mitochondrial Genomics

    Insights into Dysfunction and Disease
    • 1 Edición
    • Aruna Pal + 1 más
    • Inglés
    Mitochondrial Genomics and Mitochondrial Dysfunction in Diseases all 37 mitochondrial genes and their role in immunity. It describes mitochondrial genetics, organization of mitochondrial genes, and their role in immunity against various disease states in animal models. This title also discusses the role of nuclear genes involved in mitochondrial function, as well as numtogenesis and its role in immune function. It provides a holistic introduction to the study of mitochondrial genomics, or mitogenomics. Co-authored by two experts in mitochondrial determinants of health, early chapters describe the structural organization of mitochondria and mitochondrial genetics using different animal models. Central chapters discuss the role of mitogenomics in metabolic, viral, bacterial, and parasitic diseases, fungal infestations, neurodegenerative disorders, and cancer. The book concludes with the prospects of studying mitochondrial genes using next generation sequencing and the various methodologies for correction of genetic defects in mitochondria. Mitochondrial Genomics and Mitochondrial Dysfunction in Diseases offers a strong foundation for academic researchers, industry scientists, and students interested in disease resistance, immunology, and mitogenomics.

  • Native and Modified Starches for Food Applications

    • 1 Edición
    • Pothiyappan Karthik + 2 más
    • Inglés
    Native and Modified Starches for Food Applications, a volume in the Applications of Starches in Food and Packaging series, provides an in-depth exploration of the diverse types and sources of starches, their functional properties, and their applications in various culinary contexts. Chapters cover the gelatinization process, texture modification, and sustainable utilization of starches in addition to exploring future directions in starch research and applications. As the food industry continues to seek natural, functional ingredients, this resource meets the demand for a comprehensive and up-to-date exploration of the use of starches in food applications.Users will find this to be a great resource for facilitating informed decision-making in recipe development, processing techniques, and the creation of innovative, sustainable, and gluten-free food products.

  • Photonic Sensors for Detection of VOC Biomarkers

    Technological Principles and Medical Applications
    • 1 Edición
    • Sridhar Krishnaswamy + 2 más
    • Inglés
    VOCs available in exhaled human breath are the products of metabolic activity in the body and, therefore, any changes in their control level can be utilized to diagnose specific diseases. More than 1000 VOCs have been identified in exhaled human breath along with the respiratory droplets which provide rich information on overall health conditions. Photonic Sensors for Detection of VOC Biomarkers: Technological Principles and Medical Applications cover the introductory information on VOCs, their source in the human body, associated diseases, potential sensing materials used for selective detection, and the advancement in their sensing technology. These VOCs offer great potential as a biomarker for a disease that can be sampled non-invasively from exhaled breath with breath biopsy. However, it is still a great challenge to develop a rapid responsive, highly selective, and sensitive VOC-sensing system. This book analyzes all the challenges and their possible solutions that can be used to achieve target-specific detection and real-time monitoring of the VOC molecules in the exhaled breath. It also covers a detailed discussion of all the sensing materials developed for selective and sensitive detection of VOC molecules and their integration with photonic devices in order to develop miniature technology. It covers various miniature sensing systems that are being exploited in VOC sensing such as interferometer, Bragg grating, microstructured fiber, 3D printed optical sensing systems, etc. The book will also provide an overview of the FEM technique and computation methods used to optimize the optical sensing devices before their practical realization. Photonic sensors for detection of VOC biomarkers aims to provide comprehensive information to early career professionals and boost their existing knowledge in the area of Chemistry and Biomedical Engineering.

  • Drug Targeting Complexity

    Tissue-Specific Regulation and Molecular Paradigms in Cancer Therapy
    • 1 Edición
    • Lalit Kumar + 2 más
    • Inglés
    Drug Targeting Complexity: Tissue-Specific Regulation and Molecular Paradigms in Cancer Therapy presents a rigorous examination of advanced strategies for the selective targeting of neoplastic cells and their distinct microenvironments. This comprehensive volume elucidates both tissue-specific and tumor-specific molecular targets, clarifying how these methodologies can significantly enhance therapeutic precision while mitigating off-target effects. The initial section of the text provides an in-depth analysis of tissue-specific regulatory targets across various organs, including the liver, lungs, brain, skin, and bones. It delineates the critical mediators and mechanisms that govern tumor immunity, thereby identifying novel therapeutic avenues.Each chapter meticulously evaluates key regulatory molecules such as TGF-β, CTLA-4, and IL-10, exploring their roles in tumorigenesis and the potential for targeted interventions across a spectrum of malignancies. Subsequent sections focus on tumor tissue-specific molecular targets, encompassing immunological checkpoints, growth factors, and signaling pathways pertinent to cancers of the liver, stomach, ovary, prostate, and colon. The text provides insights into the application of monoclonal antibodies and molecular inhibitors as strategies to impede cancer progression and address therapeutic resistance. Concluding chapters address emerging therapeutic paradigms, including precision medicine and nanotechnology.

  • Artificial Intelligence in Behavioral and Mental Health Care

    • 2 Edición
    • David D. Luxton
    • Inglés
    "Artificial Intelligence in Behavioral and Mental Healthcare", Second Edition, focuses on modern developments in AI and their specific application in mental health practice and research. AI technologies are transforming how mental and behavioral health care is provided and conducted. This updated edition summarizes recent advances in artificial intelligence in mental health clinical practice and research. Each chapter provides a technical description of the advance, a review of application in clinical practice, and empirical data on clinical efficacy. In addition, each chapter includes a discussion of practical issues in clinical settings, ethical considerations, and use limitations. New to this edition are chapters on topics such as machine learning in clinical and research settings, workflow efficiency through task automation, and how AI can be used to aid in precision health and medicine. This book will be helpful to mental health practitioners interested in learning about or incorporating AI advances into their practice and for researchers interested in a comprehensive review of these advances in one source. This book helps solve the problem of disparate, non-specific, or overgeneralized information by consolidating need-to-know information in one comprehensive reference volume specific to behavioral and mental health.

  • How Plant-Based Fermented Foods are Shaping the Future of Health and Sustainability

    • 1 Edición
    • Volumen 120
    • Inglés
    How Plant-Based Fermented Foods are Shaping the Future of Health and Sustainability, Volume 120 in the Advances in Food and Nutrition Research series, presents interesting chapters on topics such as What is the role of fermented plant foods in sustainable and secure food systems?, Recent trends in plant-based fermented foods: fermentation technologies and their impacts on phytochemicals and health benefits, Beyond dairy: The science and sustainability of plant-based yogurt alternatives, Designing fermentation to enhance oat and faba bean properties, The role of fermentation in digestion of plant-based food, Fermented Plant-Based Diets and Gut Health: A Critical Evaluation, and much more.Additional chapters cover B vitamins bioavailability in plant-based fermented foods: Beyond content to nutritional impact and Legume Fermentation: Nutritional Benefits and Emerging Applications.

  • The Metallome in Motion

    Insights into Ecosystem and Food Chain Toxicodynamics
    • 1 Edición
    • Vandana Singh + 3 más
    • Inglés
    The Metallome in Motion: Insights into Ecosystem and Food Chain Toxicodynamics fills a vital gap by integrating multidisciplinary research on how metals influence biological systems, food safety, and environmental health. The book’s contents span a wide range of interrelated topics, beginning with metal-mediated epigenetic modifications and toxicodynamics at the molecular and cellular levels. Other sections explore the geochemical and anthropogenic origins of contaminants, factors affecting metal bioavailability, and the synergistic effects of metal-radical interactions. In addition, detailed chapters address the roles of metalloproteins, pathways of bioaccumulation and trophic transfer, transgenerational toxicity, and hidden reservoirs such as soil microaggregates.Adva... analytical methods, the emerging field of toxicometallomics, impacts of metals in agriculture, quantum effects of nanoparticles, and global regulatory frameworks are also thoroughly discussed, making this an essential reference for postgraduate students in food science, as well as academics and researchers in agriculture, plant science, environmental science, and biotechnology.

  • Advances in Rice Research for Abiotic Stress Tolerance

    • 2 Edición
    • Mirza Hasanuzzaman + 3 más
    • Inglés
    Rice production is increasingly challenged by abiotic stresses—such as extreme temperatures, drought, salinity, and flooding—which undermine both yield and grain quality. Tackling these constraints is crucial for global food security and depends on improved farming practices, the development of resilient cultivars, and the adoption of emerging technologies.Advance... of Rice Research for Abiotic Stress Tolerance, Second Edition, integrates new research across multiple fronts, including advances in genetic markers, modern breeding approaches, and biotechnological tools. It updates readers on cutting‑edge methodologies to mitigate climate‑related impacts and introduces expanded content on microbiome‑driven resilience, sustainable cultivation and intensification techniques, and genome editing applications that enhance crop performance under environmental stress. By capturing current global trends alongside practical solutions in rice science, the volume serves researchers, educators, and professionals working across agronomy, plant physiology, molecular biology, soil science, and related disciplines.

  • Whey

    Composition, Processing, Applications, Health Benefits and Waste Utilization
    • 1 Edición
    • Bhavbhuti M. Mehta + 1 más
    • Inglés
    Whey: Composition, Processing, Applications, Health Benefits and Waste Utilization covers the basics of its chemistry and composition and its more advanced aspects and applications. The nutritive, bioactive, and functional properties covered, as well as whey's uses in the texture and stability of dairy foods. Finally, whey is discussed as a by-product of foods such as cheese and yogurt, along with methods for responsible conversion into valuable products to minimize environmental impact. Written with a student and early-career audience in mind, this work offers a one-stop-shop to all aspects of a key dairy component that has exciting potential for future research.This book will particularly benefit graduate and post graduate students, as well as post docs and early career researchers in dairy science, food science, and nutrition. Experienced scientists will also find this book useful as a starting point for new research projects.

  • Advancements in Personalized Cellular Immunotherapy

    A Comprehensive Guide to Cancer Treatment
    • 1 Edición
    • Arun Kumar Singh + 3 más
    • Inglés
    Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment is an authoritative guide that delves into the foundational principles, recent advancements, and clinical applications of this innovative treatment approach, aiming to bridge the gap between research and clinical practice. It offers a thorough analysis of the mechanisms of action, therapeutic efficacy, and safety profiles of various cellular immunotherapy modalities, enabling clinicians to make well-informed treatment decisions and optimize patient outcomes. The book promotes interdisciplinary collaboration by bringing together experts from oncology, immunology, molecular biology, and translational medicine. Through detailed case studies, clinical guidelines, and practical insights, it provides healthcare professionals with the knowledge and tools needed to effectively incorporate cellular immunotherapy into standard oncology practice. Additionally, the book addresses key challenges and future directions in the field, such as strategies to enhance treatment efficacy, overcome resistance mechanisms, and broaden the accessibility of cellular immunotherapy to more patients. Advancements in Personalized Cellular Immunotherapy: A Comprehensive Guide to Cancer Treatment aims to educate and empower healthcare professionals, fostering continued innovation and collaboration to improve cancer care and patient outcomes.

  • Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research

    • 1 Edición
    • Frederic Sampedro
    • Inglés
    Advances in Diffusion Magnetic Resonance Imaging for Neurodegenerative Diseases Research covers how diffusion MRI has contributed to our understanding of common neurodegenerative diseases, bridging common microstructural changes across symptoms and disorders. Sections cover the technical basis of diffusion MRI, focusing on the interpretation of its imaging-derived metrics in terms of neuronal damage. Subsequent chapters are organized by disease, taking an in-depth look at how the use of diffusion MRI has contributed to recent understanding, and how it has motivated potential new therapeutic structures for Alzheimer’s disease, frontotemporal dementia, primary aggressive aphasia, Parkinson’s disease, progressive supranuclear palsy, Huntington’s disease, and more.The book concludes with implications for future research, making it a must-have reference for researchers and clinicians interested in the field of neuroimaging for neurodegenerative disorders.

  • Advanced MR Techniques for Neurodegenerative Diseases

    • 1 Edición
    • Volumen 14
    • Kannie Wy Chan + 3 más
    • Inglés
    Advanced MR Techniques for Neurodegenerative Diseases covers state of the art developments in physiologic, metabolic, functional, and microstructural MRI of the brain. It provides an overview of these approaches and includes dynamic contrast enhanced (DCE) MRI, dynamic susceptibility contrast (DSC) MRI, arterial spin labeling (ASL), chemical exchange saturation transfer (CEST) MRI, magnetic resonance spectroscopy (MRS), resting state functional MRI (rsfMRI), microscopic diffusion imaging, and quantitative susceptibility mapping (QSM). Chapters then follow that present the application of these methods to Alzheimer’s Disease and vascular dementia, small vessel disease, Parkinson’s Disease, Lewy body dementia, Huntington’s Disease, Amyotrophic Lateral Sclerosis, and Multiple Sclerosis.Advanced MR Techniques for Neurodegenerative Diseases is a comprehensive resource on the latest advanced MR techniques and their application to neurodegenerative diseases, suitable for MR engineers and physicists as well as clinicians and neuroscientists who use MR techniques for diagnosis and research.

  • Microglial Advances in Neurodegenerative Diseases

    • 1 Edición
    • Volumen 171
    • Inglés
    Microglial Advances in Neurodegenerative Diseases, Volume 170 in the Advances in Immunology series, presents current developments and comprehensive reviews focused on the role of microglia and neuroinflammation in neurological and psychiatric disorders. This volume brings together contributions from leading researchers, offering up-to-date insights into microglial biology in health and disease, as well as their involvement in major neurodegenerative conditions. Chapters in this new release explore Cross-talk between Tau and Neuro-glia Axis of Alzheimer’s Disease, Microglia in Health and Disease, Amyloid-beta (Aβ) and Neuroinflammation in Microglia, Chemokine Receptor CX3CR1 Interacts with Tau and Regulates Microglial Activity in Alzheimer’s Disease, and much more.Additional chapters explore Human-Induced Pluripotent Stem Cells in Psychiatric Disorders, GPCR-Mediated Internalization and Endosomal Sorting of the Tau–GPCR Complex in Microglia, iPSC-Derived Microglia: A Cellular Platform for Tau and Alzheimer’s Disease Immunotherapy, Advancements in Invasive and Non-Invasive Neuromodulation for Parkinson’s Disease, LRRK2-I1371V Disrupts Microglial Membrane Homeostasis and Enhances α-Synuclein Toxicity, Microglial Advances in Parkinson’s Disease, Microglial Advances in Alzheimer’s Disease, and more.

  • Microbiome in Head and Neck Cancer: Pathogenesis, Diagnosis and Therapeutic Implications

    Part B
    • 1 Edición
    • Volumen 170
    • Inglés
    Advances in Immunology, Volume 170 presents current developments and comprehensive reviews in immunology. This volume focuses on mechanisms of gasdermin activation and pyroptosis, providing insights into inflammatory cell death and immune signaling, and serving as a valuable reference for researchers in the field.

  • Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease

    • 1 Edición
    • Dibyajyoti Banerjee
    • Inglés
    Insights and Implications of Pseudo Esterase Activity of Human Serum Albumin in Diabetic Kidney Disease provides a comprehensive exploration of diabetic nephropathy, emphasizing the critical need for early detection methods prior to the onset of microalbuminuria. The book's primary focus is on the study of pseudoesterase activity in urinary albumin and other proteins as a potential biomarker for early diagnosis of diabetic kidney disease. This resource bridges a significant gap in current literature by providing an in-depth analysis of how this enzymatic activity can inform the classification and management of diabetic nephropathy.Chapters cover foundational knowledge of diabetes and its complications, the mechanisms of diabetic nephropathy, and detailed discussions on human serum albumin and its enzymatic activities. Each chapter covers the biochemical characterization of pseudoesterase activity, methods for its detection, and the significance of urinary proteomic profiling. Final chapters highlight future research opportunities and the potential for developing point-of-care testing tools, positioning this work as a critical resource for advancing the field of diabetic kidney disease research and clinical practice.

  • Diagnostic Reasoning

    Laboratory-Based Case Studies in Clinical Chemistry
    • 1 Edición
    • Ibrahim A. Hashim
    • Inglés
    Training in clinical chemistry is acquired via different avenues that include didactic lectures on pathophysiology of disease, methodologies and practical aspects of testing, and through attendance of operations meetings, sign-out sessions, seminars and tutorials. There is little instruction on how to apply the vast amount of knowledge gained in the process to practice. In other branches of medicine, cases are regularly presented with clinical information and therapeutic interventions which form the basis of training. Diagnostic Reasoning: Laboratory-Based Case Studies in Clinical Chemistry fills this gap for clinical chemistry. The concise and practical approach of the book, including real-life scenarios, is an excellent resource for pathology trainees, clinical laboratory science students, clinical chemistry fellows, clinical laboratory professionals, and clinicians. These cases help professionals remain competent in the field and be successful in their board exams. The cases are stated as they present, often with no or few clinical details accompanying the sample request with only barcoded samples arriving into the laboratory. In a busy laboratory, thousands of these cases are received daily and it is impossible to review the clinical information associated with the specimens.

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