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Elsevier

Libros en Ciencias de la Vida

  • Biomembrane Vesicles: Scientific, Clinical and Technological Considerations

    • 1 Edición
    • Volumen 32
    • Inglés
    Biological Membrane Vesicles: Scientific, Biotechnological and Clinical Considerations, Part 1 Volume 32 in the Advances in Biomembranes and Lipid Self-Assembly series, highlights new advances in the field, with this release presenting chapters written by an international board of authors. Topics in this new release include Amyloid β-peptide interaction with GM1 containing model membrane, The Human EV Membranome, Protocol for isolation of Microvesicles form blood plasma, Urinary Extracellular Vesicles: Single patient analysis for clinical applications, Treatment of chronic wounds with platelet and extracellular vesicles enriched plasma, Liposome loading and imaging, Standardization and reproducibility in EV research: the support of a Quality management system, and much more.

  • Considering the Patient in Pediatric Drug Development

    How Good Intentions Turned Into Harm
    • 1 Edición
    • Klaus Rose
    • Inglés
    Considering the Patient in Pediatric Drug Development: How Good Intentions Turned into Harm addresses a fundamental challenge in drug development and healthcare for young patients. In clinical trials and clinical practice, the term "children" is used ambiguously to confer physiological characteristics to a chronological age limit, which in reality does not exist. This book outlines why the United States (US) and European Union's (EU) regulatory authorities, pediatric academia, and the pharmaceutical industry demand, support and perform pediatric drug studies, along with the key flaws of this demand that blurs the different administrative and physiological meanings of the term "child." In addition, the book covers why most pediatric regulatory studies lack medical sense and many even harm young patients and the conflicts of interest behind pediatric drug studies. It includes relevant information about the maturation of the human body regarding absorption, distribution, metabolism and excretion of food and drugs as well as key differences between newborns, infants, older children and adolescents.

  • Trends in Wheat and Bread Making

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Trends in Wheat and Bread Making provides a comprehensive look at the state-of-the-art in bread making from ingredient to shelf-life, with a focus on the impact of processing on the nutritional value and consumer acceptability of this global staple. The book also includes chapters on new breads and bakery products fortified with plant-processing-by-... and/or natural antioxidants, and explores efforts to improve biotechnological processes and fermentation for bread making. It is an excellent resource for researchers, industry professionals and enterprises hoping to produce enhanced bread products through processing-related nutritional and quality improvements.

  • Improving Cereal Productivity through Climate Smart Practices

    • 1 Edición
    • Sindhu Sareen + 5 más
    • Inglés
    Improving Cereal Productivity through Climate Smart Practices is based on the presentations of the 4th International Group Meeting on "Wheat productivity enhancement through climate smart practices," and moves beyond the presentations to provide additional depth and breadth on this important topic. Focused specifically on wheat, and with chapters contributed by globally renowned pioneers in the field of cereal science, the book helps readers understand climate change and its effects on different aspects of wheat production in different parts of the world. This book will be important for those in research and industry seeking to contribute to the effective feeding of the world’s population.

  • Food Authentication and Traceability

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Food Authenticity and Traceability covers the most recent trends and important topics in food authentication, with an emphasis on the components of a food traceability systems. The book discusses techniques such as omics-based technologies, chromatographic methods, mass spectrometry, hyperspectral and chemical imaging, molecular and DNA-based techniques, chemometrics and data mining algorithms, high-throughput sequencing, and non-targeted fingerprinting approaches and proteomics.

  • Design and Optimization of Innovative Food Processing Techniques Assisted by Ultrasound

    Developing Healthier and Sustainable Food Products
    • 1 Edición
    • Francisco J. Barba + 4 más
    • Inglés
    Design and Optimization of Innovative Food Processing Techniques Assisted by Ultrasound: Developing Healthier and Sustainable Food Products is a useful tool in understanding the innovative applications derived from the use of ultrasound technology. The book is a starting point for product development, covering technological, physicochemical and nutritional perspectives, as well as the reduction of food toxics and contaminants. Divided into three parts, sections cover ultrasound usage in obtaining functional foods, extracting bioactive compounds, the improvement of food quality, ultrasound use for the development of novel applications, and more. As the definitive resource in new innovative ultrasound-based emerging processes, this book is a necessity for food scientists and technologists, nutrition researchers, and those working in the food manufacturing industry.

  • Pulse Foods

    Processing, Quality and Nutraceutical Applications
    • 2 Edición
    • Brijesh K. Tiwari + 2 más
    • Inglés
    Pulse Foods: Processing, Quality and Nutraceutical Applications, Second Edition, provides up-to-date information on emerging technologies for the processing of whole pulses, techniques for fractionating pulses into ingredients, their functional and nutritional properties, as well as their potential applications, so that the food industry can incorporate pulses into new food products. Since the first edition, significant developments have occurred in various aspects of pulse, pulse chemistry, processing and applications. This second edition provides thorough and authoritative coverage of pulse quality, technology and nutraceutical applications. Pulse Foods: Processing, Quality and Nutraceutical Applications, Second Edition, will continue to be an important resource for academics, students, researchers and industry professionals in providing essential details on various aspects of pulse foods.

  • Artificial Intelligence to Solve Pervasive Internet of Things Issues

    • 1 Edición
    • Gurjit Kaur + 2 más
    • Inglés
    Artificial Intelligence to Solve Pervasive Internet of Things Issues discusses standards and technologies and wide-ranging technology areas and their applications and challenges, including discussions on architectures, frameworks, applications, best practices, methods and techniques required for integrating AI to resolve IoT issues. Chapters also provide step-by-step measures, practices and solutions to tackle vital decision-making and practical issues affecting IoT technology, including autonomous devices and computerized systems. Such issues range from adopting, mitigating, maintaining, modernizing and protecting AI and IoT infrastructure components such as scalability, sustainability, latency, system decentralization and maintainability. The book enables readers to explore, discover and implement new solutions for integrating AI to solve IoT issues. Resolving these issues will help readers address many real-world applications in areas such as scientific research, healthcare, defense, aeronautics, engineering, social media, and many others.

  • Agricultural Water Management

    Theories and Practices
    • 1 Edición
    • Prashant K. Srivastava + 3 más
    • Inglés
    Agricultural Water Management: Theories and Practices advances the scientific understanding, development and application of agricultural water management through an integrated approach. This book presents a collection of recent developments and applications of agricultural water management from advanced sources, such as satellite, mesoscale and climate models that are integrated with conceptual modeling systems. Users will find sections on drought, irrigation scheduling, weather forecasting, climate change, precipitation forecasting, and more. By linking these systems, this book provides the first resource to promote the synergistic and multidisciplinary activities of scientists in hydro-meteorological and agricultural sciences. As agricultural water management has gained considerable momentum in recent decades among the earth and environmental science communities as they seek solutions and an understanding of the concepts integral to agricultural water management, this book is an ideal resource for study and reference.

  • Environmental Impact of Agro-Food Industry and Food Consumption

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Environmental Impact of Agro-Food Industry and Food Consumption covers trends associated with the impact of food production on the environment using lifecycle analysis and the standard methods used to estimate the food industry’s environmental impact. The book discusses city-scale actions to estimate the environmental impact of food systems, including the meat chain, feeding crops to farmed fish, the confectionary industry, agriculture, tea processing, cheese production, the dairy industry, cold chain, and ice cream production. Food waste and consumption in hospitality and global diets round out these interesting discussions. Written for food scientists, technologists, engineers, chemists, governmental regulatory bodies, environmentalists, environmental technologists, environmental engineers, researchers, academics and professionals working in the food industry, this book is an essential resource on sustainability in the food industry.

  • Toxicology

    Oxidative Stress and Dietary Antioxidants
    • 1 Edición
    • Vinood B. Patel + 1 más
    • Inglés
    Toxicology: Oxidative Stress and Dietary Antioxidants examines the nature of oxidative stress as a consequence of exposure to toxins and how antioxidant approaches can mitigate the impact of toxicant exposures. Sections covers the basic biology of oxidative stress, from molecular biology, to physiological pathology, mechanisms of action of specific toxicants, metals and other chemicals/drugs, and antioxidant approaches and therapies for toxic exposures. With contributions from an international group of experts, useful summary sections, a dictionary of terms, and applications to other areas of toxicology, this book is an informative, consolidated reference that helps bridge the interrelationship between toxicology, oxidative stress and antioxidants.

  • Food Structure and Functionality

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Food Structure and Functionality helps users further understand the latest research related to food structuring and de-structuring, with an emphasis on structuring to achieve improved texture, taste perception, health and shelf-stability. Topics covered address food structure, nanotechnology and functionality, with an emphasis on the novel experimental and modeling approaches used to link structure and functionality in food. The book also covers food structure design across the lifespan, as well as design for healthcare and medical applications. Dairy matrices for oral and gut functionality is also discussed, as is deconstructing dairy matrices for the release of nutrient and flavor components. This book will benefit food scientists, technologists, engineers and physical chemists working in the whole food science field, new product developers, researchers, academics and professionals working in the food industry, including nutritionists, dieticians, physicians, biochemists and biophysicists.

  • Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance

    • 1 Edición
    • Volumen 12
    • Andrew Freywald + 1 más
    • Inglés
    Biological Mechanisms and the Advancing Approaches to Overcoming Cancer Drug Resistance, Volume 12, discusses new approaches that are being undertaken to counteract tumor plasticity, understand and tackle the interactions with the microenvironment, and disrupt the rewiring of malignant cells or bypass biological mechanism of resistance by using targeted radionuclide therapies. This book provides a unique opportunity to the reader to understand the fundamental causes of drug resistance and how different approaches are applied. It is a one-stop-shop to understand why it is so difficult to treat cancer, and why only a very few patients respond to therapy and a significant portion develop resistance. Despite a rapid development of more effective anti-cancer drugs and combination therapies, cancer remains the leading cause of lethality in the developed world. The main reason for this is the ability of heterogeneous subpopulations of tumor cells interacting with constantly evolving tumor microenvironment to resist elimination and eventually, trigger cancer relapse. In this book, experts review current concepts explaining molecular and biological mechanisms of cancer drug resistance and discussing advancing approaches for overcoming these therapeutic challenges.

  • Digital Health

    Mobile and Wearable Devices for Participatory Health Applications
    • 1 Edición
    • Shabbir Syed-Abdul + 2 más
    • Inglés
    Digital Health: Mobile and Wearable Devices for Participatory Health Applications is a key reference for engineering and clinical professionals considering the development or implementation of mobile and wearable solutions in the healthcare domain. The book presents a comprehensive overview of devices and appropriateness for the respective applications. It also explores the ethical, privacy, and cybersecurity aspects inherent in networked and mobile technologies. It offers expert perspectives on various approaches to the implementation and integration of these devices and applications across all areas of healthcare. The book is designed with a multidisciplinary audience in mind; from software developers and biomedical engineers who are designing these devices to clinical professionals working with patients and engineers on device testing, human factors design, and user engagement/complianc...

  • Population Dynamics of the Reef Crisis

    • 1 Edición
    • Volumen 87
    • Inglés
    Population Dynamics of the Reef Crisis, Volume 87 in the Advances in Marine Biology series, updates on many topics that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. Chapters in this new release cover SCTL disease and coral population dynamics in S-Florida, Spatial dynamics of juvenile corals in the Persian/Arabian Gulf, Surprising stability in sea urchin populations following shifts to algal dominance on heavily bleached reefs, Biophysical model of population connectivity in the Persian Gulf, Population dynamics of 20-year decline in clownfish anemones on coral reefs at Eilat, northern Red Sea, and much more.

  • Herbal Medicine in Andrology

    • 1 Edición
    • Ralf Henkel + 1 más
    • Inglés
    Herbal Medicine in Andrology: An Evidence-Based Update provides a comprehensive overview of ethnomedical approaches in andrology, including ethnopharmacology of plant extracts and relevant bioactive compounds. It highlights information on the availability of medicinal plants and the legal and procedural processes involved in developing a marketable product. This reference helps clinicians and scientists develop an understanding on how herbal medicine can be used to treat andrological patients in practice. Only a limited number of journal articles are available on this topic, making this reference a valuable source of information for a large audience, including urologists, andrologists, gynecologists, reproductive endocrinologists and basic scientists.

  • Pediatric Reference Intervals

    • 8 Edición
    • Edward C.C. Wong + 4 más
    • Inglés
    Pediatric Reference Intervals, Eighth Edition, is a must-have for clinical chemists, hematologists, pathologists, endocrinologists and pediatricians. This trusted source enhances interpretation of patient results, allows comparison of test results using different methods, and helps optimize patient care. This updated edition is a valuable reference, providing instant and accurate reference intervals for over 250 chemistry and hematology analytes in an alphabetized, user-friendly format. Changes to this edition include Age- and Sex-Related Reference Ranges, Methodologies, Type of Specimen, References, Statistical Basis and Population Sources.

  • Long Noncoding RNAs in Plants

    Roles in Development and Stress
    • 1 Edición
    • Santosh Kumar Upadhyay
    • Inglés
    The growth of human population has increased the demand for improved yield and quality of crops and horticultural plants. However, plant productivity continues to be threatened by stresses such as heat, cold, drought, heavy metals, UV radiations, bacterial and fungal pathogens, and insect pests. Long noncoding RNAs are associated with various developmental pathways, regulatory systems, abiotic and biotic stress responses and signaling, and can provide an alternative strategy for stress management in plants. Long Noncoding RNAs in Plants: Roles in development and stress provides the most recent advances in LncRNAs, including identification, characterization, and their potential applications and uses. Introductory chapters include the basic features and brief history of development of lncRNAs studies in plants. The book then provides the knowledge about the lncRNAs in various important agricultural and horticultural crops such as cereals, legumes, fruits, vegetables, and fiber crop cotton, and their roles and applications in abiotic and biotic stress management.

  • Biocontrol Agents and Secondary Metabolites

    Applications and Immunization for Plant Growth and Protection
    • 1 Edición
    • Sudisha Jogaiah
    • Inglés
    Biocontrol and Secondary Metabolites: Applications and Immunization for Plant Growth and Protection covers established and updated research on emerging trends in plant defense signaling in, and during, stress phases. Other topics cover growth at interface as a sustainable way of life and the context of human welfare and conservation of fungi as a group of organisms. Further, the book explores induced systemic resistance using biocontrol agents and/or secondary metabolites as a milestone for sustainable agricultural production, thus providing opportunities for the minimization or elimination of the use of fungicides.

  • Clinical Bioenergetics

    From Pathophysiology to Clinical Translation
    • 1 Edición
    • Sergej M. Ostojic
    • Inglés
    Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others.

  • Developmental Human Behavioral Epigenetics

    Principles, Methods, Evidence, and Future Directions
    • 1 Edición
    • Volumen 23
    • Livio Provenzi + 1 más
    • Inglés
    Developmental Human Behavioral Epigenetics: Principles, Methods, Evidence, and Future Directions, Volume 23, a new volume in the Translational Epigenetics series, offers the first systematic account of theoretical G79 frameworks, methodological approaches, findings, and future directions in the field of human behavioral epigenetics. Featuring contributions from leading scientists and international researchers, this book provides a comprehensive overview of human behavioral epigenetics, with a close examination of evidence gathered to-date from animal models, challenges of human-based research and clinical translation, pathways towards drug discovery, and next steps in research. Areas of focus include prenatal stress exposures, preterm behavioral epigenetics, intergenerational exposures, trauma and neglect, socio-economic conditions, maternal caregiving and attachment, study design, and epigenetics and psychotherapy.

  • Protocols in Biochemistry and Clinical Biochemistry

    • 1 Edición
    • Shweta Pandey + 2 más
    • Inglés
    Protocols in Biochemistry and Clinical Biochemistry offers clear, applied instruction to fundamental biochemistry methods and protocols, from buffer preparation to nucleic acid purification, protein, lipid, carbohydrate, and enzyme testing, and clinical testing of vitamins, glucose and cholesterol levels, among other diagnostics. Each protocol is illustrated with step-by-step instructions, labeled diagrams, and color images, as well as a thorough overview of materials and equipment, precursor techniques, safety considerations and standards, analysis and statistics, alternative methods and troubleshooting.

  • Advances in Immunology

    • 1 Edición
    • Volumen 148
    • Inglés
    Advances in Immunology, Volume 148 offers the latest release in a long-established and highly respected publication, presenting current developments and comprehensive reviews in immunology. Sections in this new volume include chapters on histone deacetylases as targets in autoimmune and autoinflammatory diseases, the role of NK cell as central communicators in cancer immunity, and the mechanism and regulation of class switch recombination by transcriptional control element.

  • Nutraceuticals in Brain Health and Beyond

    • 1 Edición
    • Dilip Ghosh
    • Inglés
    Nutraceuticals in Brain Health and Beyond focuses on a variety of health disorders where intervention with nutritional supplements prove valuable, such as Alzheimer’s, Parkinson’s, autism, and attention-deficit disorder in children. In addition, Nutraceuticals in Brain Health and Beyond addresses "herb-nutra psychiatry" which is a field of research focused on developing a comprehensive, cohesive, and scientifically rigorous evidence base to shift conceptual thinking around the role of diet and nutrition in mental health.Intended for nutrition researchers, nutritionists, dieticians, regulatory bodies, health professionals, and students studying related fields, Nutraceuticals in Brain Health and Beyond will be a useful reference in understanding the links between nutrition and brain health.

  • Handbook of Deep Learning in Biomedical Engineering

    Techniques and Applications
    • 1 Edición
    • Valentina Emilia Balas + 2 más
    • Inglés
    Deep Learning (DL) is a method of machine learning, running over Artificial Neural Networks, that uses multiple layers to extract high-level features from large amounts of raw data. Deep Learning methods apply levels of learning to transform input data into more abstract and composite information. Handbook for Deep Learning in Biomedical Engineering: Techniques and Applications gives readers a complete overview of the essential concepts of Deep Learning and its applications in the field of Biomedical Engineering. Deep learning has been rapidly developed in recent years, in terms of both methodological constructs and practical applications. Deep Learning provides computational models of multiple processing layers to learn and represent data with higher levels of abstraction. It is able to implicitly capture intricate structures of large-scale data and is ideally suited to many of the hardware architectures that are currently available. The ever-expanding amount of data that can be gathered through biomedical and clinical information sensing devices necessitates the development of machine learning and AI techniques such as Deep Learning and Convolutional Neural Networks to process and evaluate the data. Some examples of biomedical and clinical sensing devices that use Deep Learning include: Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Ultrasound, Single Photon Emission Computed Tomography (SPECT), Positron Emission Tomography (PET), Magnetic Particle Imaging, EE/MEG, Optical Microscopy and Tomography, Photoacoustic Tomography, Electron Tomography, and Atomic Force Microscopy. Handbook for Deep Learning in Biomedical Engineering: Techniques and Applications provides the most complete coverage of Deep Learning applications in biomedical engineering available, including detailed real-world applications in areas such as computational neuroscience, neuroimaging, data fusion, medical image processing, neurological disorder diagnosis for diseases such as Alzheimer’s, ADHD, and ASD, tumor prediction, as well as translational multimodal imaging analysis.

  • Food Toxicology and Forensics

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Food Toxicology and Forensics presents an overview on these subjects, along with the analytical tools necessary to handle the complexity of the issues at play between them. The book discusses the presence of foreign substances in food despite forensic analysis and supports the scientific community, laboratories and regulatory bodies in their aim to identify food fraud. Topics include the forensic attribution profiling of food by liquid chromatography (LC), contemporary mass spectrometry (MS), tandem mass spectrometry (MS/MS) and liquid chromatography coupled to mass spectrometry (LC-MS), the application of ambient ionization mass spectrometry (AIMS) techniques for the analysis of food samples, and more.

  • Steviol Glycosides

    Production, Properties, and Applications
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Steviol Glycosides: Production, Properties, and Applications illustrates the health effects of steviol glycosides, presenting methods to preserve their stability, bioactivity and bioavailability during handling, extraction and processing. Beginning with biosynthesis, metabolism and health uses, the book also explores agronomic practices, toxicology and pharmacology, leaf drying, conventional techniques, non-thermal technologies, green recovery, membrane clarification technologies, chemical and enzymatic modifications, stability studies and food applications. This book is an excellent resource for food scientists, technologists, engineers, chemists, nutritionists, new product developers, researchers and academics with an interest in understanding steviol glycoside applications in the development of functional foods, nutraceuticals and pharmaceuticals.

  • Neuro-Oncology for the Clinical Neurologist

    • 1 Edición
    • Roy E. Strowd
    • Inglés
    In the growing field of neuro-oncology, the past few years have witnessed rapid advances in tumor classification, treatment modalities, and the role of neurologists and neuro-oncologists. Neuro-Oncology for the Clinical Neurologist is a first-of-its-kind resource that focuses on patient-clinical scenarios relevant to the practicing neurologist—bringing you up to date with everything from basic principles and neuro-oncology imaging consults to neurologic complications of radiation, systemic, and immune-based therapies, and much more.

  • Comprehensive Foodomics

    • 1 Edición
    • Alejandro Cifuentes
    • Inglés
    Comprehensive Foodomics, Three Volume Set offers a definitive collection of over 150 articles that provide researchers with innovative answers to crucial questions relating to food quality, safety and its vital and complex links to our health. Topics covered include transcriptomics, proteomics, metabolomics, genomics, green foodomics, epigenetics and noncoding RNA, food safety, food bioactivity and health, food quality and traceability, data treatment and systems biology. Logically structured into 10 focused sections, each article is authored by world leading scientists who cover the whole breadth of Omics and related technologies, including the latest advances and applications. By bringing all this information together in an easily navigable reference, food scientists and nutritionists in both academia and industry will find it the perfect, modern day compendium for frequent reference. List of sections and Section Editors: Genomics - Olivia McAuliffe, Dept of Food Biosciences, Moorepark, Fermoy, Co. Cork, Ireland Epigenetics & Noncoding RNA - Juan Cui, Department of Computer Science & Engineering, University of Nebraska-Lincoln, Lincoln, NE Transcriptomics - Robert Henry, Queensland Alliance for Agriculture and Food Innovation, The University of Queensland, St Lucia, Australia Proteomics - Jens Brockmeyer, Institute of Biochemistry and Technical Biochemistry, University Stuttgart, Germany Metabolomics - Philippe Schmitt-Kopplin, Research Unit Analytical BioGeoChemistry, Neuherberg, Germany Omics data treatment, System Biology and Foodomics - Carlos Leon Canseco, Visiting Professor, Biomedical Engineering, Universidad Carlos III de Madrid Green Foodomics - Elena Ibanez, Foodomics Lab, CIAL, CSIC, Madrid, Spain Food safety and Foodomics - Djuro Josić, Professor Medicine (Research) Warren Alpert Medical School, Brown University, Providence, RI, USA & Sandra Kraljević Pavelić, University of Rijeka, Department of Biotechnology, Rijeka, Croatia Food Quality, Traceability and Foodomics - Daniel Cozzolino, Centre for Nutrition and Food Sciences, The University of Queensland, Queensland, Australia Food Bioactivity, Health and Foodomics - Miguel Herrero, Department of Bioactivity and Food Analysis, Foodomics Lab, CIAL, CSIC, Madrid, Spain

  • Technical Aspects of Modern Coronary Artery Bypass Surgery

    • 1 Edición
    • Mario Gaudino
    • Inglés
    Coronary surgery encompasses two thirds of all adult cardiac surgery cases. With the endless pursuit of better outcomes, modern coronary artery bypass grafting (CABG) has become technically more complex in ways that are well beyond the training of the average cardiac surgeon. The old concept of "one-technique-fits-... has been abandoned in favour of a specialized approach tailored to the individual patient. In fact, in recent years, there is a growing movement towards establishing coronary surgery as a super-specialization of cardiac surgery. Technical Aspects of Modern Coronary Artery Bypass Surgery aims to expand on both the basics and complexities of the technical aspects of coronary surgery. It serves as an up to date resource that illustrates and details the advancement and techniques in this field which may soon become a separate super-specialty. With a particular emphasis on illustrations, the book will be an essential reference book for both established surgeons that have no experience in advanced CABG, and the new generation of CABG surgeons.

  • Healthcare Paradigms in the Internet of Things Ecosystem

    • 1 Edición
    • Valentina Emilia Balas + 1 más
    • Inglés
    Health Care Paradigms in the Internet of Things Ecosystem brings all IoT-enabled health care related technologies into a single platform so that undergraduate and postgraduate students, researchers, academicians and industry leaders can easily understand IoT-based healthcare systems. The book uses data and network engineering and intelligent decision support system-by-design principles to design a reliable IoT-enabled health care ecosystem and to implement cyber-physical pervasive infrastructure solutions. It takes the reader on a journey that begins with understanding the healthcare monitoring paradigm in IoT-enabled technologies and how it can be applied in various aspects. In addition, the book walks readers through real-time challenges and presents a guide on how to build a safe infrastructure for IoT-based health care. It also helps researchers and practitioners understand the e-health care architecture through IoT and the state-of-the-art in IoT countermeasures. Readers will find this to be a comprehensive discussion on functional frameworks for IoT-based healthcare systems, intelligent medicine, RFID technology, HMI, Cognitive Interpretation, Brain-Computer Interface, Remote Health Monitoring systems, wearable sensors, WBAN, and security and privacy issues in IoT-based health care monitoring systems.

  • Drug Delivery Devices and Therapeutic Systems

    • 1 Edición
    • Eric Chappel
    • Inglés
    Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.

  • Pediatric Endocrinology, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1 Edición
    • Volumen 49-4
    • Andrea Kelly
    • Inglés
    This issue of Endocrinology and Metabolism Clinics will cover Pediatric Endocrinology. Curated by Dr. Andrea Kelly, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series Consulting Editor, Adriana G. Ioachimescu. The volume will include articles on: Endocrine Sequelae in Childhood Cancer Survivors, Bone Health in Childhood Chronic Disease, Advances in Bone Health Assessment, Inhaled Glucocorticoids and Endocrine Outcomes, Atypical DM (mitochondrial, transplant, CFRD, monogenic), Pediatric Thyroid Cancer (outcomes, genetics, therapeutics), New Technologies in Type 1 diabetes (bionic pancreas, insulin, mobile health), Precocious and Delayed Puberty—Genetic Underpinnings and treatments (various GNRH formulations, implant), Pediatric Type 2 diabetes, Adolescent health outcomes in relation to phthalates.

  • Galapagos Giant Tortoises

    • 1 Edición
    • Inglés
    Galapagos Giant Tortoises brings together researchers and conservationists to share the most up-to-date knowledge of Galapagos giant tortoises. Despite being icons of the world-famous Galapagos Archipelago and the target of more than 50 years of conservation research and management, Galapagos giant tortoise evolution and much of their ecology remained unknown until recently. This book documents the history, the pressing conservation issues, and success stories recovering several of the 15 different species of Galapagos tortoises from near extinction.The book begins with an overview of the history of the relationship between humans and Galapagos giant tortoises, starting from initial heavy exploitation of tortoises by pirates and whalers, and extending to the start of the modern conservation era in the 1960s. The book then shifts to biology, describing Galapagos tortoise evolution, taxonomy, ecology, habitats, reproduction, and behavior. Next the decades of conservation efforts and their results are reviewed, including issues　of captive breeding, invasive species, introduced diseases, and de-extinction, as well as the current status and distribution of every species. The final portion of the book turns to four case studies of restoration, and then looks ahead to the future of all tortoise populations.The latest volume in the Biodiversity of the World: Conservation from Genes to Landscape series, Galapagos Giant Tortoises is a valuable resource for researchers and conservationists, as well as students of biology, wildlife conservation, and herpetology.

  • Overcoming Ovarian Cancer Chemoresistance

    • 1 Edición
    • Volumen 11
    • Goli Samimi + 1 más
    • Inglés
    Overcoming Ovarian Cancer Chemoresistance presents non-overlapping review chapters that discuss the state of the field in overcoming chemoresistance of ovarian cancer and treatment options before and following recurrence, considering the genetic makeup of the ovarian cancer patient and her tumor. With the uptake of both germline and somatic gene testing, clinicians can obtain a more comprehensive understanding of ovarian tumors and this book provides information to link the genetic makeup of a tumor (or patient) with the best available treatment. The book discusses topics such as strategies to fight chemo-resistance in ovarian cancer, circulating DNA as a monitor of response, BRCA mutations, ovarian cancer stem cells, immunotherapy and vaccines. Additionally, it brings a list of promising agents at clinical and pre-clinical stage that will impact the treatment in the near future. This book is a valuable source for cancer researchers, oncologists and several members of biomedical field who need to understand how to battle chemoresistance in ovarian cancer.

  • Origins of Human Socialization

    • 1 Edición
    • Donald W. Pfaff
    • Inglés
    Origins of Human Socialization introduces a new concept on the origins of basic human instinct. The book combines the three disciplinary approaches, including neuroscience, paleoanthropology and developmental psychology as an intertwined foundation for prosocial behavior. It argues that humans have the basic brain mechanisms for prosocial activity, offering new insights into more sophisticated social behavior. It also examines both visual and auditory systems in both humans and animals to explain the evolution of social interactions. Written by world-renowned researcher Dr. Donald Pfaff, this book is the first to explore why we have basic social instinct and how it works. For centuries, researchers have argued over the foundations of human behavior in society. Anthropologists point to transitions from hunter/gathers to urban dwellers leading to human domestication. Developmental psychologists highlight social competences in babies. Neuroscientists focus on specific genetic and neurochemical mechanisms that attribute to social behavior. This book brings all of these important areas together in an interdisciplinary approach that helps readers understand how they are linked.

  • A Theranostic and Precision Medicine Approach for Female-Specific Cancers

    • 1 Edición
    • Rama Rao Malla + 1 más
    • Inglés
    A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of biomedical field who need to understand the most recent and promising approaches to manage FSCs.

  • Handbook of Hydrocolloids

    • 3 Edición
    • Glyn O. Phillips + 1 más
    • Inglés
    Handbook of Hydrocolloids, Third Edition is a must-have substantive reference on hydrocolloids, helping food industry scientists ever since its first edition was published and well received. This thoroughly updated and expanded edition reviews the structure, function, properties, and applications of a broad range of hydrocolloids used in food and related industries. The third edition updates existing chapters on developments and theories on the structure and functional characteristics of individual hydrocolloids. The book provides additional chapters on new techniques for the chemical and physicochemical characterization of hydrocolloids, and applications technologies for encapsulation and controlled release of active compounds. Edited by two leading international authorities in the field, this third edition continues to be relevant to food industry researchers, food manufacturers, graduate and postgraduate students, particularly in food, pharmaceutical, and cosmetic sciences.

  • Bio-economy and Agri-production

    Concepts and Evidence
    • 1 Edición
    • Dionysis Bochtis + 3 más
    • Inglés
    Bio-Economy and Agri-Production: Concepts and Evidence bridges the knowledge gap between sustainability and bio-economy aspects of agri-production. It complements traditional perspectives of agri-production with advanced engineering, information and communication technologies recently applied in agri-business. Including knowledgebased agriculture and reflecting sustainability and circular economy principles, the book presents a holistic view of sustainable bio-economy, contributing to the development of integrated agricultural systems. As technology advances, agricultural production management practices are now being called upon to address the need for sustainability in the bio-economy. Bio-Economy and Agri-Production: Concepts and Evidence presents information to broaden the awareness and promotion of practices and technology to reduce the use of inputs, protect health and environment and improve resource-use efficiency. Topics that are addressed include circular economy in agri-business, lifecycle thinking, lean management, agri-chains, green production, and waste management. Bio-Economy and Agri-Production: Concepts and Evidence is a valuable reference for professionals, consultants, and policy making stakeholders in biosystems engineering and agricultural industries

  • Concepts and Experimental Protocols of Modelling and Informatics in Drug Design

    • 1 Edición
    • Om Silakari + 1 más
    • Inglés
    Concepts and Experimental Protocols of Modelling and Informatics in Drug Design discusses each experimental protocol utilized in the field of bioinformatics, focusing especially on computer modeling for drug development. It helps the user in understanding the field of computer-aided molecular modeling (CAMM) by presenting solved exercises and examples. The book discusses topics such as fundamentals of molecular modeling, QSAR model generation, protein databases and how to use them to select and analyze protein structure, and pharmacophore modeling for drug targets. Additionally, it discusses data retrieval system, molecular surfaces, and freeware and online servers. The book is a valuable source for graduate students and researchers on bioinformatics, molecular modeling, biotechnology and several members of biomedical field who need to understand more about computer-aided molecular modeling.

  • Side Effects of Drugs Annual

    • 1 Edición
    • Volumen 42
    • Inglés
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 42, first published in 1977, and continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered in this new release include Central Nervous System Stimulants and Drugs that Suppress Appetite, Antidepressants, Lithium, Drugs of Abuse, Hypnotics and Sedatives, Antipsychotic Drugs, Antiepileptics, Opioid Analgesics and Narcotic Antagonists, Anti-Inflammatory and Antipyretic Analgesics and Drugs Used in Gout, and much more.

  • Saffron

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Saffron explores the properties, metabolism and health effects of saffron ingredients, along with processing issues and the industrial applications that are affected by these aspects. The book addresses the in vitro and in vivo antioxidant activities of bioactive compounds found in saffron and investigates recovery methods for the extraction of these target ingredients, as well as their encapsulation. Each of these methods aims to prevent the degradation of saffron's bioactive compounds by environmental factors and to improve their bioavailability in different applications. The book is an excellent reference for food scientists, technologists, chemists, new product developers, researchers, academics, professionals working in the food industry, and pharmacologists, pharmacists and clinicians interested in nutrition and metabolism.

  • Preparation of Phytopharmaceuticals for the Management of Disorders

    The Development of Nutraceuticals and Traditional Medicine
    • 1 Edición
    • Chukwuebuka Egbuna + 2 más
    • Inglés
    Preparation of Phytopharmaceuticals for the Management of Disorders: The Development of Nutraceuticals and Traditional Medicine presents comprehensive coverage and recent advances surrounding phytopharmaceuticals... nutraceuticals and traditional and alternative systems of medicines. Sections cover the concepts of phytopharmaceuticals... their history, and current highlights in phytomedicine. Also included are classifications of crude drugs, herbal remedies and toxicity, traditional and alternative systems of medicine, nanotechnology applications, and herbal cosmeticology. Final sections cover applications of microbiology and biotechnology in drug discovery. This book provides key information for everyone interested in drug discovery, including medicinal chemists, nutritionists, biochemists, toxicologists, drug developers and health care professionals. Students, professors and researchers working in the area of pharmaceutical sciences and beyond will also find the book useful.

  • Innovation in Clinical Trial Methodologies

    Lessons Learned during the Corona Pandemic
    • 1 Edición
    • Peter Schueler
    • Inglés
    Innovation in Clinical Trial Methodologies: Lessons Learned during the Corona Pandemic presents a selection of updated chapters from Re-Engineering Clinical Trials that feature innovative options and methods in clinical trials. The Coronavirus pandemic is an accelerator for digitalization in many industries, including clinical trials. This book considers best practices, alternative study concepts requiring fewer patients, studies with less patient interaction, the design of "virtualized" protocols, and moving from data to decisions. This book will be helpful to pharmacologists, physicians and clinical researchers involved in the process of clinical development and clinical trial design.

  • Remington

    The Science and Practice of Pharmacy
    • 23 Edición
    • Adeboye Adejare
    • Inglés
    The PCP's Bicentennial Edition Remington: The Science and Practice of Pharmacy, Twenty Third Edition, offers a trusted, completely updated source of information for education, training, and development of pharmacists. Published for the first time with Elsevier, this edition includes coverage of biologics and biosimilars as uses of those therapeutics have increased substantially since the previous edition. Also discussed are formulations, drug delivery (including prodrugs, salts, polymorphism. With clear, detailed color illustrations, fundamental information on a range of pharmaceutical science areas, and information on new developments in industry, pharmaceutical industry scientists, especially those involved in drug discovery and development will find this edition of Remington an essential reference. Intellectual property professionals will also find this reference helpful to cite in patents and resulting litigations. Additional graduate and postgraduate students in Pharmacy and Pharmaceutical Sciences will refer to this book in courses dealing with medicinal chemistry and pharmaceutics.

  • Advances in Insect Physiology

    • 1 Edición
    • Volumen 59
    • Inglés
    Advances in Insect Physiology, Volume 59, examines the molecular and developmental origins of insect extended phenotypes, their diverse physiological functions, their consequences for the ecology and evolution of insects, and their biotic partners. Chapters cover recent ideas about the significance and roles of extended phenotypes and provide overviews of the latest advances. Written for a broad audience of researchers and students, the book's chapters establish extended phenotypes as focal structures for understanding genotype-to-phenotyp... maps, the origins and consequences of complex traits among multiple interacting partners, and the roles they may play in providing resilience against climate change.

  • Advanced Methods in Molecular Biology and Biotechnology

    A Practical Lab Manual
    • 1 Edición
    • Khalid Z. Masoodi + 2 más
    • Inglés
    Advanced Methods in Molecular Biology and Biotechnology: A Practical Lab Manual is a concise reference on common protocols and techniques for advanced molecular biology and biotechnology experimentation. Each chapter focuses on a different method, providing an overview before delving deeper into the procedure in a step-by-step approach. Techniques covered include genomic DNA extraction using cetyl trimethylammonium bromide (CTAB) and chloroform extraction, chromatographic techniques, ELISA, hybridization, gel electrophoresis, dot blot analysis and methods for studying polymerase chain reactions. Laboratory protocols and standard operating procedures for key equipment are also discussed, providing an instructive overview for lab work. This practical guide focuses on the latest advances and innovations in methods for molecular biology and biotechnology investigation, helping researchers and practitioners enhance and advance their own methodologies and take their work to the next level.

  • Advances in Microbial Physiology Volume 77

    • 1 Edición
    • Volumen 77
    • Robert K. Poole
    • Inglés
    Advances in Microbial Physiology, Volume 77, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The updated release contains updates in the field, with comprehensive chapters covering Microbubble Intensification of Bioprocessing, Bacterial cellulose: biosynthesis, production, and applications, Microbial energy management – a product of three broad tradeoffs, and more.

  • Soils and Landscape Restoration

    • 1 Edición
    • John A. Stanturf + 1 más
    • Inglés
    Soils and Landscape Restoration provides a multidisciplinary synthesis on the sustainable management and restoration of soils in various landscapes. The book presents applicable knowledge of above- and below-ground interactions and biome specific realizations along with in-depth investigations of particular soil degradation pathways. It focuses on severely degraded soils (e.g., eroded, salinized, mined) as well as the restoration of wetlands, grasslands and forests. The book addresses the need to bring together current perspectives on land degradation and restoration in soil science and restoration ecology to better incorporate soil-based information when restoration plans are formulated.

  • Fungi Bio-prospects in Sustainable Agriculture, Environment and Nano-technology

    Volume 2: Extremophilic Fungi and Myco-mediated Environmental Management
    • 1 Edición
    • Vijay Kumar Sharma + 3 más
    • Inglés
    Fungi Bio-prospects in Sustainable Agriculture, Environment and Nanotechnology, Volume Two: Extremophilic Fungi and Myco-mediated Environmental Management explores varied aspects of fungal biology and their relevance in microbiology and agriculture, thus allowing for better insights on basic and advanced biotechnological application in human welfare and sustainable agriculture. Chapters throw light on different sectors of fungi, including fungi in extreme circumstances, bioremediation, complex and toxic effluents, and mycoremediation. The book was designed to explore the possibility of huge fungal diversity for present and future generation in different sectors of human life. Volume Two focuses on extremophilic fungi and myco-mediated environmental management.

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