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Elsevier

Libros en Ciencias de la Vida

  • Translational Systems Medicine and Oral Disease

    • 1 Edición
    • Stephen T. Sonis + 1 más
    • Inglés
    Translational Systems Medicine and Oral Disease bridges the gap between discovery science and clinical oral medicine, providing opportunities for both the scientific and clinical communities to understand how to apply recent findings in cell biology, genomic profiling, and systems medicine to favorably impact the diagnosis, treatment and management of oral diseases. Fully illustrated chapters from leading international contributors explore clinical applications of genomics, proteomics, metabolomics, microbiomics and epigenetics, as well as analytic methods and functional omics in oral medicine. Disease specific chapters detail systems approaches to periodontal disease, salivary gland diseases, oral cancer, bone disease, and autoimmune disease, among others. In addition, the book emphasizes biological synergisms across disciplines and their translational impact for clinicians, researchers and students in the fields of dentistry, dermatology, gastroenterology, otolaryngology, oncology and primary care.

  • Mosquitoes, Communities, and Public Health in Texas

    • 1 Edición
    • Mustapha Debboun + 2 más
    • Inglés
    Mosquitoes, Communities, and Public Health in Texas focuses on 87 known species of mosquitoes found throughout Texas. It includes information on the ecology, medical and public health importance, and biological diversity of each species. In addition, it provides detailed identification keys for both larval and adult stages of all mosquito genera and species known to occur in Texas, along a review of surveillance and control strategies. The expansion of invasive mosquitoes from other regions (including Mexico), together with climate change occurrences increase the likelihood for an increase in diseases, such as West Nile Virus, Yellow Fever, Dengue, Chikungunya and Zika. This unique work is the first unified reference and resource rich in mosquito information for medical entomologists, mosquito and vector control professionals, pest management professionals, biologists, environmentalists, wildlife professionals, government regulators, instructors of medical entomology and public health professionals who have disease or vector responsibilities, mosquito taxonomists, epidemiologists, entomology students, academia, pest control industry, and libraries, etc., with utility for medical, veterinary and health professionals.

  • Therapeutic Drug Monitoring Data

    A Concise Guide
    • 4 Edición
    • Amitava Dasgupta + 1 más
    • Inglés
    Therapeutic Drug Monitoring Data: A Concise Guide, Fourth Edition serves as a ready resource of information on commonly monitored drugs that will help readers make decisions relating to the monitoring and interpretation of results. It is an easy-to-read source of information on intended use, pharmacokinetics, therapeutic range, and toxic concentrations, as well as bioavailability, disposition, metabolism and the excretion of commonly monitored therapeutic drugs. This fully updated fourth edition includes sections on new anticonvulsants, anti-depressant and anti-HIV drugs, new drugs for advanced cancer treatment, and thoroughly updated chapters that address new pitfalls and problems in the lab.

  • Emerging and Reemerging Viral Pathogens

    Volume 2: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens
    • 1 Edición
    • Moulay Mustapha Ennaji
    • Inglés
    Emerging and Reemerging Viral Pathogens: Applied Virology Approaches Related to Human, Animal and Environmental Pathogens, Volume Two presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control.

  • Complementary Strategies to Study Virus Structure and Function

    • 1 Edición
    • Volumen 105
    • Inglés
    Complementary Strategies to Study Virus Structure and Function, Volume 104, the latest release in the Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters on X-ray structures from crystals of viral proteins grown in cellula, NMR and SAXS to study protein dynamics and natively disordered viral proteins, Mass spectrometry to study virus particle assembly, Atomic force microscopy to study virus particles, Non-enveloped viruses and interactions with antibodies, Non-enveloped viruses and their mechanism of entry into cells, Structures of enveloped virions by electron cryo-microscopy and cryo-tomography, and many other interesting topics.

  • Emergence of Pharmaceutical Industry Growth with Industrial IoT Approach

    • 1 Edición
    • Valentina Emilia Balas + 2 más
    • Inglés
    Emergence of Pharmaceutical Industry Growth with Industrial IoT Approach uses an innovative approach to explore how the Internet of Things (IoT) and big data can improve approaches, create efficiencies and make discoveries. Rapid growth of the IoT has encouraged many companies in the manufacturing sector to make use of this technology to unlock its potential. Pharmaceutical manufacturing companies are no exception to this, as IoT has the potential to revolutionize aspects of the pharmaceutical manufacturing process, from drug discovery to manufacturing. Using clear, concise language and real world case studies, this book discusses systems level from both a human-factors point-of-view and the perspective of networking, databases, privacy and anti-spoofing. The wide variety of topics presented offers readers multiple perspectives on a how to integrate the Internet of Things into pharmaceutical manufacturing.

  • Coffee Consumption and Industry Strategies in Brazil

    A Volume in the Consumer Science and Strategic Marketing Series
    • 1 Edición
    • Luciana Florêncio de Almeida + 1 más
    • Inglés
    Coffee Consumption and Industry Strategies in Brazil, the latest release in the Consumer Science and Strategic Marketing series, provides an overview of the coffee sector, focusing on marketing strategies, consumer behavior, and strategies for transforming coffee consumption, production and retailing. The book presents the importance of an academician-practiti... perspective to bridge the gap between scholars and managers, and between business schools and the entrepreneurial world. Appropriate for researchers in the fields of food retail and producing, food marketing, consumer behavior, consumer science, agribusiness marketing and strategy, food industry strategy, undergraduate and post-graduate students studying marketing, consumer behavior, strategy, agribusiness marketing and strategy, practitioners in the food industry, marketing managers, and marketing and strategy consultants, this book is a must-read for those contributing to the coffee industry.

  • Regional Network for Asian Schistosomiasis and Other Helminthic Zoonoses

    • 1 Edición
    • Volumen 105
    • X. Zhou + 2 más
    • Inglés
    Regional Network for Asian Schistosomiasis and Other Helminthic Zoonoses, Volume 105, the latest release in the Advances in Parasitology series, captures the journey of RNAS+ from its early beginnings, to its current state, marking its accomplishments and impacts in research. Sections in this updated volume include Milestones of networking and global engagements for the RNAS+, Priorities and outcomes of collaborative researches for the RNAS+, Needs and coordination mechanism for capacity building by the RNAS+, Translational research and contributions to country control, Multi-disciplinary integration of networking through the RNAS+, Impact assessment of RNAS+ outcomes, and more.

  • Gases in Agro-food Processes

    • 1 Edición
    • Remy Cachon + 2 más
    • Inglés
    Gases in Agro-food Processes is the ultimate reference covering all applications of gases in agro-Food processes, from farm to fork. Divided into 11 sections, the book covers chemical and physical gas properties, gas monitoring, regulation, heat and mass transfers. Sections are dedicated to agriculture and food processing, wastewater treatment, safety applications and market trends. Users will find this to be a valuable resource for industrial scientists and researchers in technical centers who are developing agro-food products. In addition, the book is ideal for graduate students in agro-food science, chemistry and the biosciences.

  • Genetics and Genomics of Eye Disease

    Advancing to Precision Medicine
    • 1 Edición
    • Xiaoyi Raymond Gao
    • Inglés
    Genetics and Genomics of Eye Disease: Advancing to Precision Medicine thoroughly examines the latest genomics methods for studying eye disease, including complex eye disorders associated with multiple genes. GWAS, WES, WGS, RNA-sequencing, and transcriptome analysis as employed in ocular genomics are discussed in-depth, as are genomics findings tied to early-onset glaucoma, strabismus, age-related macular degeneration, adult-onset glaucoma, diabetic retinopathy, keratoconus, and leber congenital amaurosis, among other diseases. Research and clinical specialists offer guidance on conducting preventative screenings and counseling patients, as well as the promise of machine learning, computational statistics and artificial intelligence in advancing ocular genomics research.

  • Dancing protein clouds: Intrinsically disordered proteins in health and disease, Part A

    • 1 Edición
    • Volumen 166
    • Inglés
    "Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology" represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.

  • Disorders of Sleep and Wakefulness in Parkinson's Disease

    A Case-Based Guide to Diagnosis and Management
    • 1 Edición
    • Lana Chahine
    • Inglés
    Patients with Parkinson’s disease commonly struggle with sleep disorders that which negatively affect their quality of life. Sleep Considerations in the Management of Parkinson's Disease provides a comprehensive overview of common sleep issues and related topics in in this complex field. Each chapter begins with a case that describes a typical scenario related to a sleep problem in Parkinson’s disease, followed by a discussion of both the sleep problem and the specifics of the case, providing practical, real-world information to help you provide better patient care.

  • Urban Landscape Entomology

    • 1 Edición
    • David Held
    • Inglés
    Urban Landscape Entomology provides readers with the background needed to adequately understand and manage many of the complexities of urban landscape pest management. For those who need training in landscape entomology, this work serves as a practical guidebook and resource. Its chapters include quality color images of pests, along with pest management tactics, such as tree injection procedures. This topical arrangement facilitates easy extraction of information relevant to a particular situation (e.g., management of borers) and uses practical terms without oversimplifying the subject matter. This work is an invaluable resource for practitioners of landscape entomology, including technicians and operations that service local landscape management needs, such as horticultural and turfgrass management. In addition, it is also a useful reference for advanced courses in landscape entomology.

  • GPCRs

    Structure, Function, and Drug Discovery
    • 1 Edición
    • Beata Jastrzebska + 1 más
    • Inglés
    GPCRS: Structure, Function, and Drug Discovery provides a comprehensive overview of recent discoveries and our current understanding of GPCR structure, signaling, physiology, pharmacology and methods of study. In addition to the fundamental aspects of GPCR function and dynamics, international experts discuss crystal structures, GPCR complexes with partner proteins, GPCR allosteric modulation, biased signaling through protein partners, deorphanization of GPCRs, and novel GPCR-targeting ligands that could lead to the development of new therapeutics against human diseases. GPCR association with, and possible therapeutic pathways for, retinal degenerative diseases, Alzheimer’s disease, Parkinson’s disease, cancer and diabetic nephropathy, among other illnesses, are examined in-depth.

  • Design and Operation of Human Locomotion Systems

    • 1 Edición
    • Marco Cecarelli + 1 más
    • Inglés
    Design and Operation of Locomotion Systems examines recent advances in locomotion systems with multidisciplinary viewpoints, including mechanical design, biomechanics, control and computer science. In particular, the book addresses the specifications and requirements needed to achieve the proper design of locomotion systems. The book provides insights on the gait analysis of humans by considering image capture systems. It also studies human locomotion from a rehabilitation viewpoint and outlines the design and operation of exoskeletons, both for rehabilitation and human performance enhancement tasks. Additionally, the book content ranges from fundamental theory and mathematical formulations, to practical implementations and experimental testing procedures.

  • The Theory of Endobiogeny

    Volume 3: Advanced Concepts for the Treatment of Complex Clinical Conditions
    • 1 Edición
    • Kamyar M. Hedayat + 1 más
    • Inglés
    Theory of Endobiogeny, Volume 3: Advanced Concepts for Treatment of Complex Clinical Conditions explains complex and multi-factorial disorders and diseases using the theory of endobiogeny. It provides detailed applications of biological modeling, in-depth assessment into common disorders, an endobiogenic analysis, guidance on using biological modeling tools, and suggestions for treatment using standard of care treatments that also take into account diet, lifestyle and medicinal plants. This approach is an evolution in thinking from reductionism to holism, offering advice for symptomatic treatments that can be used in conjunction with a new way of thinking about diseases and disease management.

  • Hematology and Coagulation

    A Comprehensive Review for Board Preparation, Certification and Clinical Practice
    • 2 Edición
    • Amer Wahed + 2 más
    • Inglés
    Hematology and Coagulation: A Comprehensive Review for Board Preparation, Certification and Clinical Practice, Second Edition, takes a practical and easy-to-read approach to understanding hematology and coagulation at an appropriate level for both board preparation and refresher courses. The book bridges the gap between large textbooks and medical technology books written for laboratory technicians, providing the sufficient background in genetics, toxicology and immunology that residents and medical students need to know in order to become successful physicians. Readers will use this quick reference to understand how tests are performed and how to interpret results. This clear and easy-to-read presentation of core topics and detailed case studies illustrates the application of hematopathology on patient care.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 108
    • Geoffrey M. Gadd + 1 más
    • Inglés
    Advances in Applied Microbiology, Volume 108, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas, with this updated volume including chapters covering phenotypic instability in fungi, selection criteria for probiotics for use in swine production, microalgae for biofuel production, and bacterial nanoorganelles, amongst other discussions.

  • Wearable and Implantable Medical Devices

    Applications and Challenges
    • 1 Edición
    • Nilanjan Dey + 3 más
    • Inglés
    Wearable and Implantable Medical Devices: Applications and Challenges, Fourth Edition highlights the new aspects of wearable and implanted sensors technology in the healthcare sector and monitoring systems. The book's contributions include several interdisciplinary domains, such as wearable sensors, implanted sensors devices, Internet-of-Things (IoT), security, real-time medical healthcare monitoring, WIBSN design and data management, encryption, and decision-support systems. Contributions emphasize several topics, including real-world applications and the design and implementation of wearable devices. This book demonstrates that this new field has a brilliant future in applied healthcare research and in healthcare monitoring systems.

  • Collective Behavior In Systems Biology

    A Primer on Modeling Infrastructure
    • 1 Edición
    • Assaf Steinschneider
    • Inglés
    Collective Behavior In Systems Biology: A Primer on Modeling Infrastructure offers a survey of established and emerging methods for quantifying process behavior in cellular systems. It introduces and applies mathematics and related abstract methods to processes in biological systems - why they are used, how they work, and what they mean. Emphasizing differential equations in an interdisciplinary approach, this book discusses infrastructure for kinetic modeling, technological system and control theories, optimization, and process behavior in cellular networks. The knowledge that the reader gains will be valuable for entering and keeping up with a rapidly developing discipline.

  • Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics

    Cardiovascular, Respiratory, and Gastrointestinal Disorders
    • 7 Edición
    • Reed E. Pyeritz + 2 más
    • Inglés
    Emery and Rimoin’s Principles and Practice of Medical Genetics and Genomics: Cardiovascular, Respiratory, and Gastrointestinal Disorders, Seventh Edition includes the latest information on seminal topics such as prenatal diagnosis, genome and exome sequencing, public health genetics, genetic counseling, and management and treatment strategies. This comprehensive, yet practical, resource emphasizes theory and research fundamentals relating to applications of medical genetics across the full spectrum of inherited disorders and applications to medicine. Updated sections in this release cover the genetics of cardiovascular, respiratory and gastrointestinal disorders, with an emphasis on genetic determinants and new pathways for diagnosis, prevention and disease management. In addition, genetic researchers, students and health professionals will find new and fully revised chapters on the molecular genetics of congenital heart defects, inherited cardiomyopathies, hypertension, cystic fibrosis, asthma, hereditary pulmonary emphysema, inflammatory bowel disease, and bile pigment metabolism disorders among other conditions.

  • European Whales, Dolphins, and Porpoises

    Marine Mammal Conservation in Practice
    • 1 Edición
    • Peter G. H. Evans
    • Inglés
    European Whales, Dolphins, and Porpoises: Marine Mammal Conservation in Practice presents an intimate view of the workings of international conservation agreements to protect marine mammals, detailing achievements over the last 25 years, identifying weaknesses and making recommendations that governments, scientists, marine stakeholders and the public can take to improve conservation efforts. The book is written by an experienced marine mammal scientist and award-winning conservationist, providing a unique synthesis on their status, distribution and ecology. In addition, it presents information on various conservation threats, including fisheries by catch, contaminants, noise disturbance, plastic ingestion and climate change. This comprehensive resource will appeal to marine mammal conservationists and researchers, as well as environmental and wildlife practitioners at all levels.

  • Emerging and Reemerging Viral Pathogens

    Volume 1: Fundamental and Basic Virology Aspects of Human, Animal and Plant Pathogens
    • 1 Edición
    • Moulay Mustapha Ennaji
    • Inglés
    Emerging and Reemerging Viral Pathogens: Fundamental and Basic Virology Aspects of Human, Animal and Plant Pathogens, Volume One presents new research information on viruses and their impact on the scientific community. It provides a reference book on certain viruses in humans, animals and vegetal, along with a comprehensive discussion on interspecies interactions. The book then looks at the drug, vaccine and bioinformatical strategies that can be used against these viruses, giving the reader a clear understanding of transmission. The book's end goal is to create awareness that the appearance of newly transmissible pathogens is a global risk that requires shared/adoptable policies for prevention and control.

  • Lipids and Edible Oils

    Properties, Processing and Applications
    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Lipids and Edible Oils: Properties, Processing and Applications covers the most relevant topics of lipids and edible oils, especially their properties, processing and applications. Over the last years, researchers have investigated lipid bioavailability, authentication, stability and oxidation during processing and storage, hence the development of food and non-food applications of lipids and edible oils has attracted great interest. The book explores lipid oxidation in foods, the application of lipids as nano-carriers of food bioactive compounds, and their bioavailability, metabolism and nutritional genomics. Regarding edible oils, the book thoroughly explores their triacylglycerols content, biodiesel and energy production from vegetable oils, refining and lifecycle assessment. Written by a team of interdisciplinary experts that research lipids and edible oils, the book is intended for food scientists, technologists, engineers and chemists working in the whole food science field.

  • Innovation in Health Informatics

    A Smart Healthcare Primer
    • 1 Edición
    • Miltiadis Lytras + 1 más
    • Inglés
    Innovation in Health Informatics: A Smart Healthcare Primer explains how the most recent advances in information and communication technologies have paved the way for new breakthroughs in healthcare. The book showcases current and prospective applications in a context defined by an imperative to deliver efficient, patient-centered and sustainable healthcare systems. Topics discussed include big data, medical data analytics, artificial intelligence, machine learning, virtual and augmented reality, 5g and sensors, Internet of Things, nanotechnologies and biotechnologies. Additionally, there is a discussion on social issues and policy- making for the implementation of smart healthcare. This book is a valuable resource for undergraduate and graduate students, practitioners, researchers, clinicians and data scientists who are interested in how to explore the intersections between bioinformatics and health informatics.

  • Valorization of Fruit Processing By-products

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Valorization of Fruit Processing By-products covers the most recent advances in the field of fruit processing by-products following sustainability principles. The urgent need for sustainability within the food industry necessitates research to investigate the handling of by-products with another perspective, e.g. by adapting more profitable options. This book covers the latest developments in this particular direction. It promotes success stories and solutions that ensure the sustainable management of different fruit processing by-products (namely apple, apricot, avocado, Castanea sativa, citrus, date, mango, melon, passion fruit, pineapple, pink guava, pomegranate and watermelon), giving emphasis on the recovery of polyphenols, antioxidants and dietary fiber. Written by a team of experts in food processing and engineering, chemistry and food waste, this title is the definite guide for all the involved partners, engineers, professionals and producers active in the field.

  • Methods in Kidney Cell Biology Part B

    • 1 Edición
    • Volumen 154
    • Inglés
    Methods in Kidney Cell Biology, Part B, Volume 154 represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics – a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary calcium in live cells, Differentiation of human kidney organoids from pluripotent stem cells, Quantifying autophagic flux in kidney tissue using structured illumination microscopy, the Generation of primary cells from ADPKD and normal human kidneys, ADPKD cell proliferation and Cl-dependent fluid secretion, In vitro cyst formation of ADPKD cells, and much more.

  • Real-Time Data Analytics for Large Scale Sensor Data

    • 1 Edición
    • Himansu Das + 2 más
    • Inglés
    Real-Time Data Analytics for Large-Scale Sensor Data covers the theory and applications of hardware platforms and architectures, the development of software methods, techniques and tools, applications, governance and adoption strategies for the use of massive sensor data in real-time data analytics. It presents the leading-edge research in the field and identifies future challenges in this fledging research area. The book captures the essence of real-time IoT based solutions that require a multidisciplinary approach for catering to on-the-fly processing, including methods for high performance stream processing, adaptively streaming adjustment, uncertainty handling, latency handling, and more.

  • Brain Imaging

    • 1 Edición
    • Volumen 165
    • David B. Teplow
    • Inglés
    Brain Imaging, Volume 164, the latest release in the Progress in Molecular Biology and Translational Science series, provides informative monographs on a variety of research topics related to neuroimaging in aging and neurodegenerative disease. Topics covered in this new release include FTD spectrum, Cerebrovascular disease, HIV, Huntington’s Disease, Development of brain PET imaging agents, and Disclosure of imaging biomarker results.

  • Trends in Non-alcoholic Beverages

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Trends in Nonalcoholic Beverages covers the most recent advances, production issues and nutritional and other effects of different nonalcoholic beverages, such as carbonated beverages, cereal-based beverages, energy drinks, fruit punches, non-dairy milk products, nonalcoholic beer, ready-to-drink products (e.g. tea, coffee), smoothies, sparkling and reduced water beverages. In addition, it covers relevant issues, such as traditional non-alcoholic beverages, labeling and safety issues during production, as well as the intake of functional compounds in particular applications. This is an essential resource for food scientists, technologists, engineers, nutritionists and chemists as well as professionals working in the food/beverage industry.

  • Advances in Clinical Chemistry

    • 1 Edición
    • Volumen 92
    • Inglés
    Advances in Clinical Chemistry, Volume 92, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry. It is the benchmark publication for novel analytical approaches in the clinical laboratory.

  • Nocturia

    Etiology, Pathology, Risk Factors, Treatment and Emerging Therapies
    • 1 Edición
    • King C. Lee + 1 más
    • Inglés
    Nocturia: Etiology, Pathology, Risk Factors, Treatment and Emerging Therapy includes the background, prevalence, etiology, risk factors, adverse effects and morbidity, as well as current and emerging treatments related to nocturia. Often considered a normal part of aging, nocturia can often be overlooked as a risk factor associated with serious outcomes such as mortality, morbidity, negative economic implications and decreased quality of life. This book provides comprehensive information on all aspects of nocturia as well as how the emerging therapies can provide safe, effective and low-cost treatment. This is an important reference for researchers, urologists and clinicians interested in improving diagnosis and treatment of nocturia.

  • Chronic Renal Disease

    • 2 Edición
    • Paul L. Kimmel
    • Inglés
    Chronic Renal Disease, Second Edition, comprehensively investigates the physiology, pathophysiology, treatment and management of chronic kidney disease (CKD). This translational reference takes an in-depth look at CKD with no coverage of dialysis or transplantation. Chapters are devoted to the scientific investigation of chronic kidney disease, the most common problems faced by nephrologists in the management of chronic kidney disease, specific illnesses in the CKD framework, and how the management of CKD in a polycystic kidney disease patient differs from other CKD patients. This award-winning reference features a series of case studies, covering both clinical aspects and pathophysiology. Questions are open ended, progressively more difficult, and repetitive across different patient clinical problems and different chapters. The cases and questions included will be useful for medical students, residency board reviews, and clinician teaching or conference preparation.

  • Principles of Heart Valve Engineering

    • 1 Edición
    • Arash Kheradvar
    • Inglés
    Principles of Heart Valve Engineering is the first comprehensive resource for heart valve engineering that covers a wide range of topics, including biology, epidemiology, imaging and cardiovascular medicine. It focuses on valves, therapies, and how to develop safer and more durable artificial valves. The book is suitable for an interdisciplinary audience, with contributions from bioengineers and cardiologists that includes coverage of valvular and potential future developments. This book provides an opportunity for bioengineers to study all topics relating to heart valve engineering in a single book as written by subject matter experts.

  • Dental Implants and Bone Grafts

    Materials and Biological Issues
    • 1 Edición
    • Hamdan Alghamdi + 1 más
    • Inglés
    Dental Implants and Bone Grafts: Materials and Biological Issues brings together cutting-edge research to provide detailed coverage of biomaterials for dental implants and bone graft, enabling scientists and clinicians to gain a thorough knowledge of advances and applications in this field. As tooth loss and alveolar bony defects are common and pose a significant health problem in dental clinics, this book deals with timely topics, including alveolar bone structures and pathological changes, reviews of indications and advantages of biomaterials for dental implants and bone graft, design and surface modification, biological interaction and biocompatibility of modern dental implants and bone graft, and new frontiers.This book is a highly valuable resource for scientists, clinicians and implantologists interested in biomaterial and regenerative strategies for alveolar bone reconstruction.

  • Cardiovascular Implications of Stress and Depression

    • 1 Edición
    • Paul D. Chantler + 1 más
    • Inglés
    Cardiovascular Implications of Stress and Depression provides an in-depth examination on how exposure to stress influences risk for cardiovascular disease and how depression is associated with this relationship. This authoritative volume examines causal pathways linking stress, depression and cardiovascular disease. In addition, it provides mechanistic insights into how environmental stress can lead to cardiovascular diseases. Current information about mechanistic factors, clinical and epidemiological aspects, and management issues associated with stress/depression are presented. These insights demonstrate how the mechanisms behind chronic stress and depression lead to cardiovascular diseases. In addition, their role in existing diseases (such as obesity, hypertension, and diabetes) is explored.

  • Carotenoids: Properties, Processing and Applications

    • 1 Edición
    • Charis M. Galanakis
    • Inglés
    Carotenoids: Properties, Processing, and Applications fills the gap of transfer knowledge between academia and industry, covering integral information in three critical dimensions: properties, recovery and applications. At the moment, carotenoid research is directed at particular applications, including colorants, antioxidants and recovery from plant processing by-products. These trends take into account the health, nutrition and functions of carotenoids, the new recovery efforts from underutilized sources, the extraction procedures using green solvents and technologies, and their sustainability aspects. Written by a team of experts in the field of food chemistry, food science and technology, as well as bioresource technologists mainly from academia, the book covers the most recent advances in the field of carotenoids, while also analyzing the potential of already commercialized processes and products.

  • DNA Sensors and Inflammasomes

    • 1 Edición
    • Volumen 625
    • Inglés
    DNA Sensors and Inflammasomes, Volume 625, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New sections in this release include Phosphorylation and dimerization of STING and IRF3, cGAS enzymology, Synthesis and identification of immuno-stimulatory CDNs, Tracking cGAS activity/ cGAMP formation using SPR/NMR, Using an enzyme coupled assay to track cGAS activity under steady states, Tracking the polymerization of DNA sensors, inflammasome receptors, and downstream signaling partners using FRET, NLRC4 structure, Tracking TREX1 activity, DNA association and dissociation kinetics of PARP1, and more.

  • Sports, Exercise, and Nutritional Genomics

    Current Status and Future Directions
    • 1 Edición
    • Debmalya Barh + 1 más
    • Inglés
    Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions is the first reference volume to offer a holistic examination of omics-driven advances across different aspects of exercise and sports physiology, biochemistry, sports medicine, psychology, anthropology, and sports nutrition; and highlighting the opportunities towards advance personalized training and athlete health management. More than 70 international experts from 14 countries have discussed key exercise and sport-related themes through the prism of genomics, epigenomics, transcriptomics, proteomics, metabolomics, telomere biology, talent in sport, individual differences in response to regular physical activity, that in the future may empower coaches, sports physicians, fitness experts, genetic counselors, and translational scientists to employ various omics data and approaches in improving health and physical performance of people participating in sports and exercise activities. Contributors address current knowledge of genetic influence on athletic performance, individual responses to exercise training, as well as the genetics of musculoskeletal phenotypes, exercise-related injuries, flexibility, and neurodegenerative disorders in athletes. Finally, performance-related and psychological traits associated with epigenetic, transcriptomic and metagenomic biomarkers are also considered, along with nutritional and pharmacogenomic aids in sports medicine and personalized nutrition.

  • Safety Issues in Beverage Production

    Volume 18: The Science of Beverages
    • 1 Edición
    • Alexandru Grumezescu + 1 más
    • Inglés
    Safety Issues in Beverage Production, Volume 18, in the Science of Beverages series, offers a multidisciplinary approach to the complex issues emerging in the beverage industry. The book is broad in coverage and provides the necessary foundation for a practical understanding of the topics that includes recent scientific industry developments that are explained to improve awareness, educate and create communication. The latest trends in legislation, safety management and novel technologies specific to beverages are discussed. This resource is ideal as a practical reference for scientists, engineers and regulators, but can also be used as a reference for courses.

  • Difficult to Diagnose Rare Diffuse Lung Disease

    • 1 Edición
    • Alexander V. Averyanov
    • Inglés
    Difficult to Diagnose Rare Diffuse Lung Disease presents the theoretical basis and practical aspects of differential diagnoses of rare lung diseases with the use of new method of probe-based confocal laser endomicroscopy (alveoscopy) of the distal respiratory region. Each chapter describes signs and symptoms of the disease and its typical and atypical manifestations. The book contains full color illustrations, including high-resolution histological microphotographs, CT-scans and confocal laser endomicroscopy images. In combination, these elements make this book an invaluable reference and guide for pulmonary researchers, pulmonologists, radiologists, and pathologists who wish to broaden their spectrum of knowledge in rare lung diseases.

  • Nanomycotoxicology

    Treating Mycotoxins in the Nano Way
    • 1 Edición
    • Mahendra Rai + 1 más
    • Inglés
    Nanomycotoxicology: Treating Mycotoxins in Nanoway discusses the role of nanotechnology in the detection, toxicity and management of different types of mycotoxins. Sections cover the topic of nanomycotoxicology, the application of nanotechnology for quicker, more cost-effective and precise diagnostic procedures of mycotoxins and toxicogenic fungi, and the application of nanotechnology for the management of mycotoxigenic fungi. New topics, such as the application of nanotechnology in disease management, disease forecasting, and disease resistance, mycotoxin detection, and nanodiagnostic and molecular techniques are also presented. With chapter contributions from an international group of experts, this book presents an interdisciplinary reference for scientists and researchers working in mycotoxicology, nanotechnology, mycology, plant science, and food safety. In addition, it will be a useful tool for industrial scientists investigating technologies to update their nanotoxicology and nanosafety knowledge.

  • Cellular Nutrient Utilization and Cancer

    • 1 Edición
    • Volumen 347
    • Inglés
    Cellular Nutrient Utilization and Cancer, Volume 347 in the International Review of Cell and Molecular Biology (IRCMB) series maintains a high standard by publishing invited articles on timely topics that are authored by prominent cell and molecular biologists. Sections in this new release include Sulfur metabolism and cancer, The interplay of genetic drivers of cancer and cellular nutrients to support oncogenesis, The diet’s impact on nutrient availability for cancer cells, Nutrients as determinants of redox balance in cancer, The role of dietary lipids in colon cancer pathogenesis, The influence of diet on nutrient utilization by cancer cells and immune-surveillance, and more.

  • Physics of Biological Action and Perception

    • 1 Edición
    • Mark L. Latash
    • Inglés
    Physics of Biological Action and Perception helps researchers interested in exploring biological motor control from a physics or alternative viewpoint perspective. The book introduces the idea of parametric control as a distinguishing feature of living systems. Sections cover how the CNS creates stable percepts based on fuzzy and continuously changing signals from numerous receptors and the variable processes related to ongoing actions. The author also develops the idea of control with referent coordinates to stability of salient variables in fields typically united under the label of "cognition." Examples of this include communication (how the gist of a message is preserved despite variability of phrases), thought processes (how one can solve a mental problem via different logical routes), and playing chess (how one selects an optimal move given a position on the board). The book is written for researchers, instructors, clinicians and other professionals in all the fields related to biological movement and perception.

  • How to Integrate Quality by Efficient Design (QbED) in Product Development

    • 1 Edición
    • Bhavishya Mittal
    • Inglés
    The development of a robust drug product requires juggling many competing priorities such as overcoming scientific challenges, following regulatory requirements, and managing business-related concerns. Unfortunately, despite large resources spent on R&D, multifactor productivity of pharmaceuticals is on the decline for several years now. Because of this business reality, pharmaceutical companies have seen a notable change in the traditional operating model and footprint over the past couple of decades. Outsourcing, in particular, has emerged as a successful business model for many pharmaceutical companies looking for ways to strategically increase their R&D capabilities and to augment their in-house resources. How to Integrate Quality by Efficient Design (QbED) in Product Development bridges the gap between theory and practice when it comes to strategic decision-making in a pharmaceutical research scenario. This book will introduce the concept of QbED and focus on various aspects such as patient-centric product designs, platform-based manufacturing technologies, business acuity, and regulatory strategies to balance the challenges in outsourcing with the need for strategic and statistically sound experiments rooted in good science. Detailed discussions will cover pharmaceutical business models, regulatory approval process, quality by design (QbD), business analytics, and manufacturing excellence specifically for small molecules and solid oral dosage forms. With the addition of case studies, flowcharts, diagrams, and data visualizations, How to Integrate Quality by Efficient Design (QbED) in Product Development will be a practical reference to help professionals working in the area of pharmaceutical drug development, strategy, and outsourcing management.

  • Molecular Nutrition

    Vitamins
    • 1 Edición
    • Vinood B. Patel
    • Inglés
    Molecular Nutrition: Vitamins presents the nutritional and molecular aspects of vitamins with a specific focus on vitamins A, B1 (thiamine), B2 (riboflavin), B# (niacin), B5 (pantothenic acid), B6, (pyridoxine), B7 (biotin), B9 (folate), B12 (colbamin), C, D, E, and K. As part of the Molecular Nutrition series, this book discusses introductory aspects and general coverage of vitamins and nutrition, the molecular biology of the cell, including signaling, transporters, oxidative stress, receptors, uptake, immunity, proliferation, endoplasmic reticulum, differentiation, carcinogenesis and apoptosis. Final sections cover genetic machinery and its function, transcriptional processes, homeostasis genes, cancer, gene expression, mutations, and more. Emerging fields of molecular biology and important discoveries related to diet and nutritional health are also covered, rounding out the book.

  • Patent Foramen Ovale Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia

    • 1 Edición
    • M. Khalid Mojadidi + 2 más
    • Inglés
    Patent Foramen Ovale (PFO) Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia is a complete reference covering the association between PFO and numerous medical conditions. It provides a background on the topic including embryology, anatomy, and physiology. This book fully examines the diagnosis and imaging assessment of PFO and discusses the data linking PFO to various clinical pathologies. It details technical aspects of PFO closure and includes perspectives on future outlooks and where the field is headed in terms of device closure indications. This is a complete reference book for cardiologists, interventional cardiologists, neurologists, pulmonologists, general practitioners, medical professionals, and researchers who are interested in PFO-associated pathologies, technical aspects, safety, and future outlooks of PFO device closure.

  • Management Strategies for Sustainable Cattle Production in Southern Pastures

    • 1 Edición
    • Monte Rouquette Jr. + 1 más
    • Inglés
    Management Strategies for Sustainable Cattle Production in Southern Pastures is a practical resource for scientists, students, and stakeholders who want to understand the relationships between soil-plant interactions and pasture management strategies, and the resultant performance of cow-calf and stocker cattle. This book illustrates the importance of matching cattle breed types and plant hardiness zones to optimize cattle production from forages and pastures. It explains the biologic and economic implications of grazing management decisions made to improve sustainability of pastures and cattle production while being compliant with present and future environmental concerns and cattle welfare programs.

  • Functional Food Ingredients from Plants

    • 1 Edición
    • Volumen 90
    • Inglés
    Functional Food Ingredients from Plants, Volume 90, the latest release in the Advances in Food and Nutrition Research series, provides updated knowledge about nutrients in foods and how to avoid their deficiency, especially for those essential nutrients that should be present in the diet to reduce disease risk and optimize health. Updates to this release include sections on Natural antioxidants of plant origin, Dietary fiber sources, The impact of molecular interactions with phenolic compounds on food polysaccharides functionality, Plant phenolics as functional ingredients, Pigments and vitamins from plants as functional ingredients, Glucosinolates fate from plants to consumer, and more.

  • Principles of Bone Biology

    • 4 Edición
    • John P. Bilezikian + 3 más
    • Inglés
    Preface from the first edition (1996): "The world of modern science is undergoing a number of spectacular events that are redefining our understanding of ourselves. As with any revolution, we should take stock of where we have been, where we are, and where we are going. Our special world of bone biology is participating in and taking advantage of the larger global revolution in modern science… we assembled experts from all over the world and asked them to focus on the current state of knowledge and the prospects for new knowledge in their area of expertise. To this end,　Principles of Bone Biology　was conceived." - John P. Bilezikian, Lawrence G. Raisz, Gideon A. Rodan Praise for the previous edition: "Students, teachers, and practitioners will benefit from reading it, and investigators will use it as a reference work; it will certainly be consulted frequently." --The New England Journal of Medicine For over two decades, "Big Gray" has been the go-to repository of knowledge in the disciplines related to bone and mineral metabolism. The fourth edition is a must-have for students new to the field; young investigators at the graduate or postgraduate level beginning their research careers; established scientists who need to keep up with the changing nature of the field, looking to enrich their own research programs, or who are changing their career direction; clinicians who want ready access to up-to-date relevant basic science. This new edition builds on the successful formula from previous editions, taking the reader from the basic elements of fundamental research to the most sophisticated concepts in therapeutics. Principles of Bone Biology, Fourth Edition provides the most comprehensive, authoritative reference on the study of bone biology and related diseases. Bone research continues to generate enormous attention, due to the broad public health implications of osteoporosis and related bone disorders. This classic, fully updated, two volume reference is designed for anyone involved in the study of bone biology.

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