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Elsevier

Libros en Ciencias de la Vida

  • Insect Pathology

    • 3 Edición
    • Nemat Keyhani + 2 más
    • Inglés
    Insect Pathology, Third Edition offers the most comprehensive research on the topic of insect pathology, spanning the diversity of insects with a more diverse array of microbes. This book provides a full update on new approaches for studying the genetics, development, evolution, and ecology of insect pathogens. Written by leading researchers and experts, the book includes coverage of revolutionary genome editing tools, such as CRISPR-Cas9, which have been developed for multiple insect pathogen systems and provides insights into the molecular underpinnings of insect pathogens and their hosts. This book also updates modern molecular techniques, “omics” approaches, and newly applied findings. These new and revised topics are critical for understanding current perspectives in the field, making this book a needed reference for insect pathologists, entomologists, microbiologists, mycologists, nematologists, protistologists, ecologists, and practitioners of biological control of insect pests. New and long-time students of insect pathology will also find this new edition useful.

  • Decision Neuroscience

    • 2 Edición
    • Jean-Claude Dreher
    • Inglés
    Decision Neuroscience: An Integrative Perspective, Second Edition, Volume Two presents the most recent and compelling lesional, neuroimaging, electrophysiological... and computational studies in combination with hormonal and genetic studies that have led to a clearer understanding of the neural mechanisms behind reward and decision-making. The neural bases of reward and decision-making processes are of critical interest to scientists because of the fundamental role that reward plays in a number of behavioral processes (such as motivation learning, and cognition), and because the neural bases have theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders.This book provides a comprehensive update on groundbreaking work that addresses fundamental questions about the nature of behavior, including how does the brain process reward and how does it make decisions when facing multiple options? It features entirely new content, as well as expanded coverage on drug and behavioral addiction and the role of subthalamus stimulation in neurological disorders and neuroeconomics.

  • Blood-Based Biomarkers for Alzheimers and Parkinsons Disease

    • 1 Edición
    • Volumen 191
    • Inglés
    Blood-Based Biomarkers for Alzheimer’s and Parkinson’s Disease, Volume 191 in the International Review of Neurobiology series, presents current advances and comprehensive reviews on the development and application of circulating biomarkers in neurodegenerative disorders. It brings together contributions from an international panel, highlighting emerging strategies for early detection, diagnosis, and monitoring of Alzheimer’s and Parkinson’s diseases. Chapters explore a wide range of topics, including the Diagnostic Potential of Exosomes in Neurodegenerative Diseases and Cancer, Blood Biomarkers of Oxidative Stress and Mitochondrial Dysfunction in Alzheimer’s and Parkinson’s Diseases, GFAP and the Genetic Code of Astrocyte Activation in Alzheimer’s Disease, and much more.Additional chapters cover Blood-Based Emerging Biomarkers in Early Detection and Diagnosis of Alzheimer’s Disease, Advances in Nanomaterial-Based Biomarker Detection for Neurodegenerative Diseases, Blood-Based Biomarkers in Alzheimer’s and Parkinson’s Disease: From Molecular Pathology to Therapeutic Potential, Blood-Based Biomarkers and Their Role in AD/PD Diagnosis, The Emerging Landscape of Circulatory Biomarkers in Alzheimer’s Disease, Biofluid-Based Biosensors, Biomarkers of Vascular Dementia and Alzheimer’s Disease, Silent Clues in Blood: Proteomic Approach for Alzheimer’s Disease, and more.

  • Biosimilars in Cancer

    • 1 Edición
    • Ranjita Shegokar + 1 más
    • Inglés
    Biosimilars in Cancer is a comprehensive resource on the role of biosimilars in treating various cancer types. The book offers a succinct yet thorough overview of current trends in oncology, covering 21 different cancers from liver to breast cancer. Chapters provide detailed insights into trends, fundamental facts, and practical and clinical data, making it an invaluable tool for academics and practitioners. The book empowers researchers and clinicians to enhance understanding and improve patient outcomes through the effective use of biosimilars in oncology. Targeted primarily at pharmaceutical researchers, biomedical scientists, and clinicians, it supports the growing oncology biosimilars market.In addition, the book provides critical insights for those involved in cancer diagnostics and clinical trials, helping them stay ahead in this rapidly progressing field.

  • Cell Death Part F

    • 1 Edición
    • Volumen 211
    • Inglés
    Cell Death: Part F, Volume 211 presents the latest advances and comprehensive reviews in the rapidly evolving field of cell death. This volume explores Methods to Assess BAX Conformation, Activation, Translocation, and Mitochondrial Outer Membrane Permeabilization, Proximity biotin labelling identification of Bcl-2 protein interactions in live cells, Bimolecular fluorescence complementation assays for investigating Bcl-2 family protein interactions, Assessing apoptotic sensitivity in primary mouse B cells by BH3 profiling, Liposome permeabilization assays to monitor pore formation by cell death proteins, Flow Cytometry Assessment of Mitochondrial Membrane Potential, Biomass, and ROS in OXPHOS-Dependent and Glycolytic Cancer Cells during Cell Death Induction, and much more.Additional chapters cover Assessment of Viability Versus Cell Death: What is What?, Flow cytometry-based drug response profiling of primary B-precursor ALL cells in co-culture with bone marrow-derived stromal cells, An in vitro model of efferocytosis in macrophage foam cells to probe lipid-driven dysregulation of dead cell clearance, Measuring tumor cell killing using in vivo bioluminescence imaging, and more.

  • The Human Nervous System

    • 4 Edición
    • George Paxinos + 2 más
    • Inglés
    The 4th Edition of the classic book The Human Nervous System continues to assemble contributions from world leaders in research on the brain, spinal cord and peripheral nervous system. This book has been edited by the best-known team of brain cartographers, and it has been completely revised to present the cutting edge of human neuroscience. The structure, connections and function are explained in depth, making this book essential to any student or scientist interested in brain anatomy and function.

  • Geostatistical Approaches to Environmental and Public Health Issues

    • 1 Edición
    • Deepak Kumar + 4 más
    • Inglés
    Geostatistical Approaches to Environmental and Public Health Issues discusses how geostatistical techniques can be leveraged to better understand and respond to pressing environmental and public health challenges. The book showcases how techniques like kriging, spatial regression, Bayesian modeling, and space-time analysis offer powerful, nuanced insights into these issues. Emphasizing stochastic, non-deterministic approaches, it highlights the importance of modeling uncertainty in both environmental and health domains. Through case studies and research-driven chapters, sections demonstrate how integrating geospatial and statistical methods can enhance our understanding of where, why, and how events occur—ultimately improving the precision of health interventions and environmental policies.By aligning cutting-edge statistical approaches with the geospatial dimensions of health and environmental data, this book fills a critical gap in the literature and supports more targeted, data-driven decision-making in the face of global uncertainty. It bridges methodological innovation with applied research, making it an essential resource for scientists, policymakers, and public health practitioners.

  • Electrocardiography of Laboratory Animals

    • 3 Edición
    • Meg M. Sleeper + 1 más
    • Inglés
    Electrocardiography of Laboratory Animals, Third Edition, provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book begins with the fundamental principles of electrocardiography and its applications in drug safety evaluation but then covers electrocardiography in a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees.Addition... it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. It is an essential resource for biological and medical researchers, veterinarians, zoologists, and students.

  • Personalized Cancer Medicine through Multiomics

    • 1 Edición
    • Mohammad Azhar Aziz + 1 más
    • Inglés
    Personalized Cancer Medicine through Multiomics explores the integration of multiomics to transform cancer diagnosis and treatment. The book delves into how the convergence of genomics, transcriptomics, proteomics, and metabolomics offers a comprehensive understanding of cancer biology, surpassing traditional single-omics approaches. Sections detail advancements in high-throughput technologies and computational methods, including machine learning, that enable the analysis of complex cancer datasets. Additional content discusses how multiomics identifies unique molecular signatures, novel therapeutic targets, and biomarkers, facilitating precise and individualized treatment strategies, particularly for a heterogeneous cancers.For academics, this book serves as an essential resource, compiling fragmented research into a single, coherent volume. It provides foundational knowledge, the latest advancements, and practical applications of multiomics in personalized medicine. Researchers will benefit from interdisciplinary approaches, real-world examples, and cutting-edge methodologies, making it an invaluable reference for advancing their work in oncology.

  • Understanding Molecular Processes using Electrochemical Methods

    • 1 Edición
    • Ashis Kumar Satpati + 1 más
    • Inglés
    Understanding Molecular Processes using Electrochemical Methods offers a detailed compendium of techniques for molecular analysis. The book considers step and sweep techniques, scanning electrochemical microscopy, spectroelectrochemic... techniques, electrochemiluminesc... and scanning probe techniques while also exploring COSMOL multiphysics simulation, electroanalysis in biomedical and clinical applications, and future prospects for electrochemical techniques. Chapters focus on evaluating redox reactions, biological interactions, kinetics, quorum sensing, biofilm formation, surface modification and more molecular aspects. This volume offers a deep-dive into the fundamental principles behind the latest electrochemical techniques, equipping researchers with practical guidance for their own experiments.Users will find this to be an ideal reference for researchers working across a range of disciplines including molecular biology, bioanalytical chemistry, biomedical science, and translational medicine.

  • Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases

    • 1 Edición
    • Meenakshi Dhanawat + 4 más
    • Inglés
    Diagnostic Application of Blood-based Biomarkers for Neurodegenerative Diseases is a comprehensive exploration of the pivotal role blood-based biomarkers play in diagnosing and managing neurological disorders. This comprehensive guide emphasizes the need for early detection and intervention in conditions such as Alzheimer’s disease, Parkinson’s disease, and neuroinflammation. Each chapter delves into specific biomarkers, including glial fibrillary acidic protein and neurofilaments, elucidating their diagnostic potential. This book highlights recent advancements in the application of blood biomarkers across various neurodegenerative diseases, underscoring the integration of artificial intelligence in biomarker discovery. By bridging research and clinical practice, it serves as an essential resource for professionals in diagnostic sciences, pharmaceutical research, and clinical pharmacology. Ultimately, this volume aims to reshape the landscape of early diagnosis, offering insights that promise to enhance personalized treatment strategies and improve patient outcomes in the fight against debilitating neurological disorders.

  • Biopolymer Based Nano Drug Delivery for Cancer Wound Healing

    • 1 Edición
    • Vipan Kumar + 5 más
    • Inglés
    Biopolymer Based Nano Drug Delivery for Cancer Wound Healing explores groundbreaking advancements in nanomedicine's role in treating cancer and promoting wound healing. The book delves into the pathophysiology of cancerous wounds, introduces biopolymer-based nanomedicine, and examines drug delivery systems using biopolymer-based nanoparticles. It concludes with future prospects of biopolymers in antitumor drug delivery systems. This resource is invaluable for researchers, advanced students, and R&D personnel across various fields, including cancer research, polymer science, biomaterials, biomedicine, pharmaceutics, biotechnology, and chemistry. Each chapter bridges theoretical concepts with practical applications, providing examples to illustrate key points.The book covers the pathophysiology of cancer and wounds, biopolymer-based nanomedicine for cancerous wounds, and drug delivery systems for healing. This is an essential reference for scientists and students focusing on pharmacy, drug delivery, and biomedicine.

  • Bio-Click Chemistry

    Expanding Horizons Beyond the Click
    • 1 Edición
    • Flavia Zacconi + 2 más
    • Inglés
    Bio-Click Chemistry: Expanding Horizons Beyond the Click delves into the dynamic intersection of biocatalysis and click chemistry, providing a comprehensive exploration of these rapidly evolving fields. This book offers in-depth insights into both historical perspectives and the latest advancements, ensuring readers gain a thorough understanding of fundamental principles, practical applications, and future directions. Readers will discover the versatile applications of biocatalysis and click chemistry in pharmaceuticals, biotechnology, biology, biomedicine, nanomedicine, and materials science, equipping researchers, educators, and industry professionals with the tools and techniques needed to foster innovation and real-world impact. Furthermore, the book investigates the emerging trends, challenges, and opportunities in biocatalysis and click chemistry, empowering readers to stay ahead of the curve and drive transformative developments in chemical synthesis and enzymatic engineering. This indispensable guide is designed for researchers, educators, and industry professionals dedicated to advancing their work and exploring new frontiers in chemical synthesis and biocatalytic processes.

  • The Potential of Extracellular Vesicles from Plant and Animal Sources for Improving Human Beauty and Health

    • 1 Edición
    • Khalid Rehman Hakeem + 2 más
    • Inglés
    The Potential of Extracellular Vesicles from Plant and Animal Sources for Improving Human Beauty and Health is a comprehensive resource that consolidates the latest research on the mechanisms of extracellular vesicles (EVs) and their applications in the cosmetic industry. The book explores a range of topics, including the latest techniques in isolation and characterization of EVs, safety considerations, methods, and challenges associated with large-scale production, and recent advancements in biomedical applications. The therapeutic potential of EVs for age-related neurological conditions and autoimmune skin diseases is investigated, as well as the application of EVs for skincare, hair loss and anti-aging products.The book considers EVs from a variety of sources, including humans, plants, animals and bacteria, highlighting their major differences. It also includes a discussion of market trends and the global impact for EV products in cosmetic and anti-aging industries. With growing interest in the role of extracellular vesicles in enhancing health and beauty, this book provides invaluable insights to researchers working in this field, equipping them with the knowledge to leverage EVs for innovative cosmetic applications and natural solutions.

  • Network Pharmacology

    Exploring New Horizons in Drug Discovery
    • 1 Edición
    • Veeranoot Nissapatorn + 4 más
    • Inglés
    Network Pharmacology: Exploring New Horizons in Drug Discovery explores the innovative network pharmacology approach—which examines the intricate interactions between disease targets and metabolites—offering a systems-based perspective that is essential for modern drug discovery. Readers will find in-depth discussions on metabolite databases, computational tools, and the role of natural products in drug discovery. Notable topics include network-based approaches to drug repurposing, personalized medicine, and the implications of traditional medicine in pharmacological research, all supported by real-world case studies and advanced computational methodologies.By integrating multiomics data, including metabolite profiling, the book addresses the limitations of conventional methods and opens new pathways for understanding disease mechanisms and therapeutic responses. This is a foundational guide for researchers, pharmaceutical scientists, and academic scholars across diverse fields such as pharmacology, metabolomics, and systems biology.

  • PACAP

    From Discovery to Function
    • 1 Edición
    • David Vaudry + 1 más
    • Inglés
    PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Advances in Applied Microbiology

    • 1 Edición
    • Volumen 136
    • Inglés
    Advances in Applied Microbiology provides a comprehensive overview of the latest research, innovations, and practical applications in the field of microbiology. Covering a broad spectrum of topics, this book explores recent advances in microbial biotechnology, environmental and industrial microbiology, medical and food microbiology, and emerging technologies. Each chapter highlights significant developments, challenges, and future directions, making it an invaluable resource for researchers, students, and professionals seeking to stay updated on the dynamic landscape of applied microbiology. With contributions from leading experts, this volume offers insights into the vital roles microorganisms play in various sectors, including health, agriculture, industry, and the environment.

  • Brain Point-of-Care Ultrasound

    Practical Guide and Protocols
    • 1 Edición
    • Camilo N. Rodríguez + 6 más
    • Inglés
    Brain Point-of-Care Ultrasound: Practical Guide and Protocols explores brain hemodynamics and parenchyma examination, providing an orderly and protocolized approach that facilitates individualized clinical decisions with ease. Covering ultrasound configuration, in-depth anatomical knowledge, and advanced parameters, this guide aims to integrate brain ultrasound seamlessly into the Point-of-Care Ultrasound (POCUS) modality, addressing the critical need for comprehensive patient assessment. From basic principles to specialized clinical situations, each section of this guide is meticulously crafted to empower practitioners with practical insights. Chapters explore Doppler spectral wave interpretation, angle correction nuances, autoregulation dynamics, and non-invasive pressure estimations, among others, thus enabling precise monitoring and targeted decision-making. With a focus on integration across disciplines and specialties, this book bridges the gap between classical pathology and contemporary practice, positioning brain ultrasound as a pivotal tool in the armamentarium of modern critical care.

  • Computational and Experimental Approaches in Protein Engineering and Design

    • 1 Edición
    • Aditya Kumar Padhi + 1 más
    • Inglés
    Computational and Experimental Approaches in Protein Engineering and Design offers a one-stop resource for students, researchers, and practitioners. Cutting-edge techniques in AI and machine learning applications are expertly covered in the book, empowering readers with the tools they need to tackle modern challenges in biotechnology and therapeutics. Step-by-step protocols provide readers with actionable guidance to transition smoothly from computational modelling to laboratory implementation. The inclusion of real-world case studies makes the theoretical concepts relatable and actionable and immediately applicable to solving complex problems, such as producing protein-based vaccines for immunotherapy.The book’s focus on synthetic biology positions it at the forefront of innovation, appealing to a broad audience, from those involved in tissue engineering to those exploring next-generation therapeutics. With its forward-looking approach, emphasizing machine-learning-dri... protein design and nanobody engineering, this book is an indispensable resource for researchers preparing to navigate the future of biotechnology.

  • Nano Meets Micro

    Revolutionizing Medicine through Microfluidic Devices
    • 1 Edición
    • Fatemeh Hataminia + 1 más
    • Inglés
    Nano Meets Micro: Revolutionizing Medicine through Microfluidic Devices explores the transformative potential of integrating nanotechnology with microfluidics to revolutionize medical diagnostics, treatment, and personalized medicine. The book provides a detailed examination of how these cutting-edge technologies are making healthcare more precise, efficient, and personalized. Sections highlight nanomedicine and microfluidics, highlighting their importance in healthcare and their intersection with advanced healthcare solutions. It covers traditional and emerging fabrication techniques for microfluidic devices, the design and synthesis of nanoparticles, and the integration of nanomedicine into microfluidic systems. Examples and case studies illustrate how these technologies are used in drug delivery, disease diagnosis, and rapid diagnostics.With a strong focus on future implications, the book discusses emerging trends and potential advances in microfluidics and nanotechnology, including the integration of artificial intelligence and data analytics. It addresses the challenges and future directions in the commercialization of nanomedicine and microfluidic devices, providing a roadmap for translating laboratory innovations into clinical applications.

  • The Fauna of Australia’s Tropical Savanna Biome

    Biodiversity, Biogeography, and Conservation
    • 1 Edición
    • Alan Andersen + 1 más
    • Inglés
    The Fauna of Australia's Tropical Savanna Biome: Biodiversity, Biogeography and Conservation considers the full range of vegetation types and freshwater systems that occur within the dominant savanna matrix in Australia's monsoonal tropics. Edited by renowned experts of tropical ecology, it provides descriptions of diversity, taxonomic, functional composition and endemism, and ecological and biogeographical questions of wide interest. Chapters explore how diversity and composition vary among different habitats in a savanna landscape and along the savanna rainfall gradient. The book also considers how distinctive savanna fauna is within Australia and compared with tropical savannas elsewhere in the world. The book considers the unique biogeographic and evolutionary history of this highly diverse and distinctive biome, building on a rich foundation of knowledge accrued over decades of research on many aspects of the region's biodiversity, conservation values, and challenges. This is an indispensable resource for students and researchers studying tropical biodiversity, as well as conservationists and land managers of Australia's tropical savanna biome and those found across the globe.

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1 Edición
    • Lara Scheherazade Milane + 1 más
    • Inglés
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered.Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Pulse Breeding, Processing, Functionality, and Products

    • 1 Edición
    • Fatma Boukid + 3 más
    • Inglés
    Pulse Breeding, Processing, Functionality, and Products reflects the shift from animal- to plant-based foods, addressing increased interest in pulses due to their higher protein contents when compared to most cereals. The book provides comprehensive coverage of a wide range of knowledge related to pulses, from breeding approaches and market landscapes to extraction and fractionization, post- treatments for improved ingredients, their nutritional and compositional qualities, advances in testing methods, and their potential industrial applications in food and pet food. With its inclusion of problems/solutions and issues-focused insights, the book's content is valuable for immediate application and for inspiring additional research. The book offers the food industry and researchers the necessary insights to know the latest developments and emerging uses of pulse ingredients. As pulses have high adaptability, versatility, and offer potentially significant contributions to the human diet and pulse ingredient flours, proteins, fibers, and starches, they are increasingly being used in food formulations, hence this book covers the topic with a wide breadth of knowledge. Challenges, including taste, color, bite, mouthfeel, and texture are also covered for innovative products.

  • Membrane Transporters and Drug Delivery

    A Comprehensive and Multidisciplinary Guide
    • 1 Edición
    • Elena Puris + 3 más
    • Inglés
    Membrane Transporters and Drug Delivery: A Comprehensive and Multidisciplinary Guide is a comprehensive reference on the rapidly evolving field of membrane transporters and their role in drug delivery. The book begins with a comprehensive introduction to membrane transporters and their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery, examines the roles of both efflux and influx transporters in drug pharmacokinetics, and covers different strategies for utilizing membrane transporters for drug delivery and targeting specific tissues and cell types.It concludes with a discussion on the regulatory and industrial aspects of transporter-related projects, explores the potential of artificial intelligence in transporter and drug delivery research, and offers a glimpse into future challenges and perspectives in this field.

  • Molecular Tools and Infectious Disease Epidemiology

    • 2 Edición
    • Betsy Foxman + 1 más
    • Inglés
    Molecular Tools and Infectious Disease Epidemiology, Second Edition examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology.Section... discuss how using molecular tools in epidemiologic research affects program design and conduct, consider the ethical concerns that arise in molecular epidemiologic studies, and provide a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory, and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into their studies.

  • Advances in Virus Research

    • 1 Edición
    • Volumen 126
    • Inglés
    Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Clinical Atlas of Gonioscopy

    • 1 Edición
    • Chunyan Qiao + 3 más
    • Inglés
    Clinical Atlas of Gonioscopy comprehensively and systematically covers all aspects of gonioscopy: from basic knowledge and common manifestations to characteristic signs of different diseases, and the application of gonioscopy in the laser and surgical treatment of glaucoma. Including over a thousand high-quality images, it helps clinicians explore the diverse and fascinating world of the anterior chamber angle, and deepens their understanding of the pathogenesis, classification, diagnosis, differential diagnosis, treatment and follow-ups of glaucoma.

  • Toxicology Disasters

    Causes and Consequences
    • 1 Edición
    • Sue Ford
    • Inglés
    Toxicology Disasters: Cause and Consequences, a volume in the History of Toxicology and Environmental Health series, provides an historical overview of significant toxicological disasters which involved chemical exposure of humans, animals or the environment. The book documents the timeline of events and the legacy of the resulting exposure which occurred within a specific period of time, but with long lasting consequences. Case studies of toxicological incidents and a wide range of categories, including environmental, industrial, pharmaceutical, domestic and international are not only discussed from a historical perspective but also regarding their impacted toxicology, regulation and our current use of these chemicals.The book will help toxicologists, academics and students from environmental health and toxicology departments, environmental/occupa... health regulators, and industrial hygiene/safety personnel gain a better understanding of the arc of a toxicological disaster from its origins, root causes of the problem, and initial and long-term assessments and management.

  • Gestational Diabetes Mellitus

    Epidemiology, Clinical Practice and Evidence-Based Guidelines
    • 1 Edición
    • Moshe Hod + 6 más
    • Inglés
    Gestational Diabetes Mellitus: Epidemiology, Clinical Practice and Evidence-Based Guidelines is an invaluable resource for healthcare professionals seeking to understand the latest developments in GDM. Over the past 20 years, significant progress has been made in the study of its epidemiology, mechanisms, diagnosis, management, and prevention. This book delves into these advancements, offering insights that are crucial for both researchers and clinicians. It explores potential therapeutic solutions to enhance patient care, and is essential reading for obstetricians, endocrinologists, diabetes researchers, maternal health specialists, and pediatric endocrinologists, as well as specialty fellows, residents, postdoctoral fellows, and graduate students in these fields.

  • Postharvest Loss and Waste Management of Horticultural Produce

    From Farm to Fork
    • 1 Edición
    • Zahra H. Mohammad + 2 más
    • Inglés
    Postharvest Loss and Waste Management of Horticultural Produce: From Farm to Fork addresses the major challenges and root causes of postharvest losses while also presenting solutions to reduce losses using innovative technologies. Sections introduce an overview of postharvest challenges, such as postharvest handling, storage, and transportation of fruits, vegetables, and berries, along with the impact of COVID-19 on postharvest losses. Other sections cover postharvest biological issues and control, such as postharvest diseases and microbiology issues of produce, novel technologies for reducing postharvest loss and waste in horticulture, like biological control, packaging, MAP films, etc., and mitigation strategies. A final section explores the environmental, economic, and social impact of postharvest losses across the food supply chain. Edited by a team of experts in the field, this is an excellent resource that brings sustainable solutions to reduce postharvest losses on a global level. Attracting a wider audience in the fields of food engineering and technology, as well as professionals, researchers, and academicians working in the fields of postharvest losses and their management, this book will be a welcomed resource.

  • Capsule Endoscopy in Pediatric Patients from Theory to Practice

    • 1 Edición
    • Thomas M. Attard
    • Inglés
    Capsule Endoscopy in Pediatric Patients from Theory to Practice is a practical and authoritative guide that empowers pediatric gastroenterologists, physicians, and trainees to navigate the complexities of Video Capsule Endoscopy (VCE) in children. With a focus on bridging knowledge gaps and providing practical insights, this book offers updated information on understanding and utilizing VCE in the pediatric population. The book covers the background and technical aspects of VCE, including guidance on setting up a pediatric VCE service and an overview of indications and limitations. It delves into practical aspects such as preprocedural preparation, artifact reduction techniques, and management of capsule retention. By exploring VCE in various disease conditions such as inflammatory bowel disease, gastrointestinal bleeding, hereditary polyposis syndromes, and chronic abdominal pain, readers gain a comprehensive understanding of diagnosis, surveillance, and management. Special content elements, including key terms, case studies, and a timeline of recent advances, enhance the learning experience. This essential resource empowers readers to optimize patient care, make informed decisions, and confidently navigate the realm of VCE in children.

  • Advances in Parasitology

    • 1 Edición
    • Volumen 134
    • Inglés
    Advances in Parasitology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Starch Blends and Their Applications

    Sustainable Packaging Solutions
    • 1 Edición
    • Rafael Audino Zambelli
    • Inglés
    Starch Blends and Their Applications: Sustainable Packaging Solutions, a new volume in the Applications of Starches in Food and Packaging series, discusses the latest advancements in production techniques and modification strategies for enhancing the functionality and compatibility of starch blends in multicomponent systems. The book presents case studies and real-world applications of starch blends in food processing, biodegradable materials, biomedical applications, and more, showcasing their diverse functionalities and potential benefits. Chapters also address challenges, opportunities, and future trends in starch blends research and development, offering insights into emerging technologies and areas for further exploration.Written by leading experts in the field, this book equips its audience with the knowledge, skills, and insights needed to navigate the complexities of starch blends and harness their potential in diverse applications.

  • Structural Biology of Ubiquitination

    From Mechanisms to Interventions
    • 1 Edición
    • Navaneet Chaturvedi + 1 más
    • Inglés
    Structural Biology of Ubiquitination: From Mechanisms to Interventions provides an in-depth exploration of the structural and biophysical principles governing ubiquitination and their implications in diseases such as cancer and neurodegeneration. The book seamlessly integrates experimental insights with advanced computational methods, including AI-driven drug discovery, molecular modeling, and biophysical simulations, offering a comprehensive toolkit for researchers and clinicians. By bridging fundamental science with translational applications, the book empowers readers to design targeted therapeutics, understand disease mechanisms at the molecular level, and accelerate progress toward personalized medicine.

  • Dry Eye Disease

    A Clinical Handbook
    • 1 Edición
    • James Stuart William Wolffsohn + 2 más
    • Inglés
    Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home.

  • Machine Learning and AI Technology for Agricultural Applications

    • 1 Edición
    • Kishore Chandra Swain + 5 más
    • Inglés
    Machine Learning and AI Technology in Agricultural Applications offers a comprehensive overview of how artificial intelligence and machine learning are transforming the agricultural industry. By delving into image processing and advanced data analysis, the book demonstrates how technology addresses modern agricultural challenges, including climate change, urbanization, and increasing global populations. It emphasizes the importance of integrating sensors and data collection methods to generate vast pools of information, which can be efficiently analyzed through AI-driven solutions. The text lays a strong foundation for understanding the role of technological innovation in supporting sustainable and secure food production.Beyond introducing core machine learning models such as random forest, support vector machines, logistic regression, and decision trees, the book highlights the centralization of critical agricultural data in the cloud. This resource benefits both students and seasoned agricultural scientists, providing practical insights for optimizing crop yields, monitoring soil and weather conditions, and managing resources like fertilizers and pesticides. The book also explores the rapid analysis of complex datasets, empowering users to make informed, timely decisions in real-world agricultural scenarios.

  • Practice of Neurocritical Care in Resource Limited Countries

    • 1 Edición
    • Hemanshu Prabhakar + 2 más
    • Inglés
    Practice of Neurocritical Care in Resource Limited Countries offers a comprehensive examination of the unique challenges and practical strategies for delivering neurocritical care in low- and middle-income countries (LMICs). As the prevalence of neurological emergencies continues to rise in these regions, this book addresses the critical need for effective management in resource constrained environments. It begins by exploring the landscape of neurocritical care, including common neurological emergencies and their epidemiology in LMICs. The content outlines foundational principles of patient assessment and monitoring, as well as advanced management strategies for conditions such as traumatic brain injury, stroke, and spinal cord injury. Special attention is given to the nuances of caring for diverse patient populations, including pediatric and geriatric patients. Additionally, this book highlights the essential role of pain management, and nutritional support, in neurocritical settings. With contributions from experts across various LMICs, this resource emphasizes innovative approaches to training and capacity building, empowering healthcare professionals to provide high-quality neurocritical care despite the challenges of limited resources. This book is an invaluable tool for clinicians and educators dedicated to improving outcomes for neurologically ill patients in lesser-resourced healthcare systems.

  • Plant Powered Probiotics

    Exploring Science and Health Behind Non-Dairy Fermented Beverages
    • 1 Edición
    • Pintu Choudhary + 2 más
    • Inglés
    Plant Powered Probiotics: Exploring Science and Health Behind Non-Dairy Fermented Beverages guides readers through the scientific aspects of fermentation, including detailing microbial roles, health benefits, and quality control. The book compares health advantages to other sources while emphasizing gut health and the importance of pro-and prebiotics for a healthy microbiome. Precision fermentation, strain selection, and optimized production processes are addressed, along with the safety of agro-waste of some common plant-based ingredients. The book concludes with the next generation and emerging trends in non-dairy probiotic beverage formulations.As the demand for foods containing probiotics coupled with an increased desire for dairy alternatives has opened the door for the creation of functional non-dairy beverages that have proven track records for gut and immune health, this book highlights fermentation origins, processes, and novel plant-based ingredients while also exploring health effects and digestive benefits.

  • Intelligent IoT-based Diagnostic and Assistive Systems for Neurological Disorders

    • 1 Edición
    • Hanif Heidari + 1 más
    • Inglés
    Intelligent IoT-based Diagnostic and Assistive Systems for Neurological Disorders discusses the latest developed methods in IoT and its applications in neurological disorders that emphasize end-user requirements. Intelligent IoT is used to explore the intersection between medicine, data science, biomedical engineering, and healthcare systems. A comprehensive overview of modelling and analyzing the requirements of people with neurological disorders is presented in this book. Signals and images of biological activity are collected and analyzed based on patient specifications to facilitate more accurate diagnosis and treatment. The book also discusses cutting-edge AI methods for IoT devices designed to treat neurological conditions.

  • The Analytical Chemistry of Cannabis

    Chemistry, Pharmacology, Manufacturing, Use, and Control of Medicinal Cannabis and Cannabinoid Dosage Formulations
    • 2 Edición
    • Brian F. Thomas + 2 más
    • Inglés
    The Analytical Chemistry of Cannabis: Chemistry, Pharmacology, Manufacturing, Use, and Control of Medicinal Cannabis and Cannabinoid Dosage Formulations: Second Edition presents advanced methods in analytical chemistry to address modern issues surrounding cannabis-based products. Since the first edition, the cannabis industry has rapidly expanded its array of recreational and medicinal products. This volume provides crucial methods to support the manufacturing, labeling, and distribution of safe, consistent products with known chemical content and performance. It offers updated information on the chemistry and pharmacology of cannabis and cannabinoids and aims to resolve industry challenges by fostering understanding among scientists, public health officials, and non-scientist stakeholders.The book is valuable for professionals in analytical chemistry, pharmacology, medicine, and law enforcement, as well as for advanced academic courses in related fields.

  • International Review of Neurobiology

    • 1 Edición
    • Volumen 190
    • Inglés
    International Review of Neurobiology, Volume 190 highlights new advances in the field, with this volume presenting an in-depth chapter on imaging the glymphatic system in Huntington’s disease. This contribution explores the benefits of multimodal imaging approaches and their clinical implications, offering insights into disease mechanisms and potential diagnostic strategies.This volume provides a focused and up-to-date perspective on neurobiological research, serving as a valuable resource for researchers and clinicians interested in neurodegenerative disorders and advanced imaging techniques.

  • Coral Reefs

    Their Complexity, Fragility and Future
    • 1 Edición
    • Robert Steneck
    • Inglés
    Coral Reefs: Their Complexity, Fragility and Future offers an introduction to tropical coral reef ecosystems. It explores the combined geological, physical, chemical, and biological factors that make coral reefs among the most diverse and productive systems in the world. To unpack these complex systems, this book outlines the major players that create coral reefs, reconsiders how environmental and human forces shape reefs in the Anthropocene and identifies best practices for sustainable tourism and management of reef systems. Written by a leading expert of tropical reef systems, this book covers the biology, taxonomy, and ecological interactions of dominant reef organisms. Chapters systematically discuss the diversity of corals and the reef communities that they support, the key geological and biological factors driving their development, and critical processes of primary productivity, competition, predation, and herbivory. The book ends with a look to the future of coral reefs considering global change in the Anthropocene.Coral Reefs: Their Complexity, Fragility and Future combines fundamental concepts with novel research advances to explore the forces that shape coral reefs and predict the future of these ecosystems in the coming century. In discussing both the successes and failures of modern conservation efforts, this book offers a roadmap to guide stakeholders and industry leaders in developing policies surrounding the sustainable visitation and conservation of coral reef ecosystems. It is an indispensable resource for the next generation of marine scientists, conservationists, and policymakers concerned with the future of these critical ecosystems.

  • Pharmaceutical QbD with Design of Experiments

    Statistical Tools and Applications in Drug Delivery Systems
    • 1 Edición
    • Khushwant Yadav
    • Inglés
    Pharmaceutical QbD with Design of Experiments: Statistical Tools and Applications in Drug Delivery Systems offers comprehensive coverage of best practices in pharmaceutical manufacturing. The first section discusses the principles and basics of Quality by Design (QbD). Part two covers the foundational statistical principles and tools for the Design of Experiments (DoE). Section three is dedicated to the applications of QbD for conventional formulations. The next section provides ample coverage of applications to Novel Drug Delivery Systems (NDDS), including micro and nano-particles. The final section discusses the application of QbD for the optimization of pharmaceutical processes and equipment.Researcher... in pharmaceutical manufacturing will benefit from this thorough statistical review, while students in this field will gain practical insights the experienced chapter authors provide in case studies. Industry professionals can find solutions to their particular problems within the insights and strategies shared in this book.

  • Applications of Microfluidics Device Technology

    • 1 Edición
    • Volumen 226
    • Inglés
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

  • Titanium Dioxide Nanoparticles and Aquatic Organisms

    From Molecular Mechanisms to Ecological Risks
    • 1 Edición
    • Youji Wang
    • Inglés
    Titanium Dioxide Nanoparticles and Aquatic Organisms: From Molecular Mechanisms to Ecological Risks provides a comprehensive examination of titanium dioxide nanoparticles in the aquatic environment. Despite the ubiquitous application of these nanoparticles in cosmetics, food, and industrial products, little is known about their potential long-term ecological impacts. Bioaccumulation of titanium dioxide has been widely observed, and this book summarizes the mechanisms and risks of biological uptake and dispersal through aquatic food webs. Written by a team of experts in aquatic toxicology, this book systematically explores the industrial sources of titanium dioxide nanoparticles, their introduction into the aquatic environment, and the physiological impacts to aquatic taxa spanning multiple trophic levels. Individual physiological impacts to algae, aquatic molluscs, crustaceans, and fish are explored before chapters turn to the compounding effects of climate change and natural organic matter. The book ends with an assessment of knowledge gaps and prospects for future studies. Titanium Dioxide Nanoparticles and Aquatic Organisms: From Molecular Mechanisms to Ecological Risks is an essential resource for students, young researchers, and professionals in the fields of marine biology, ecotoxicology, and materials science seeking to better understand the hazards of this pervasive pollutant and aquatic life.

  • The Renaissance in GPCR Research and Drug Discovery

    Receptor Function, Receptor Structure, New Techniques, and Characterization of Drug Activity
    • 1 Edición
    • Terry P. Kenakin
    • Inglés
    The Renaissance in GPCR Research and Drug Discovery: Receptor Function, Receptor Structure, New Techniques, Characterization of Drug Activity, Drug Discovery is a comprehensive reference for pharmacology researchers. It focuses on utilizing novel aspects of GPCR function for therapeutic advantage and applying new chemical types to modify GPCR behavior. Recent advancements have revitalized GPCR discovery, opening unexplored avenues for new drug development. The book's content is meticulously divided into five distinct parts, covering evolutionary perspectives, novel functions, investigative technologies, therapeutic modalities, and a broad range of GPCR ligands.Beyond these key topics, the book delves into the evolution of GPCRs as drug targets, the mechanisms behind their novel functions, and the latest technologies driving research and discovery. It also highlights new and recently approved therapeutic modalities and provides a broad coverage of GPCR ligands. Edited and authored by leading researchers, this book serves as an essential reference for drug discovery researchers and medicinal chemists, as well as AI researchers exploring this drug discovery space.

  • Cellular Therapies for Cancer Treatment

    Advancements in Drug Delivery Strategies
    • 1 Edición
    • Arun Kumar Singh + 3 más
    • Inglés
    Cellular Therapies for Cancer Treatment: Advancements in Drug Delivery Strategies explores the innovative use of cellular therapy to combat cancer, placing an emphasis on state-of-the-art delivery approaches. By covering a variety of cellular therapies for cancer, such as stem cells, immune cells, and others, this book provides a comprehensive introduction to the field. It describes ways to deliver drugs that target cancer cells more efficiently, decrease off-target effects, and enhance therapy outcomes. Sections provide a brief overview of cancer cell biology, describe the need for advance drug delivery systems, and address challenges and future directions.The book also goes into the ideas behind cellular therapies and how they may overcome drug resistance and make existing cancer treatments more effective. By elaborating on the value of diversity and inclusion in cancer research and treatment, the book also emphasizes the importance of all patients having equal access to innovative therapies. All things considered, this book is a great tool for researchers, doctors, and students in the cancer treatment sector.

  • Super-Resolution Nanoscopy for Protein Imaging

    • 1 Edición
    • Varun Vyas
    • Inglés
    Super-Resolution Nanoscopy for Protein Imaging decodes the intricate world of protein visualization using cutting-edge nanoscopic techniques. This comprehensive guide is crafted to equip master students, PhD candidates, and early-stage researchers with essential knowledge and practical insights into advanced protein imaging technologies. The book covers foundational principles, innovative methodologies, and real-world applications, providing a complete resource for mastering the complexities of protein imaging. This book offers a unique compilation of diverse nanoscopic methods, overcoming the limitation of technique-specific texts currently available.By collecting scattered information into a single volume, it delivers an in-depth exploration of imaging techniques, from Atomic Force Microscopy (AFM) to Electron Microscopy (EM), and Single Molecule Fluorescence Imaging. Each section delves into instrumentation, sample preparation, data analysis, and the latest developments, making it an indispensable reference for understanding how to visualize proteins in their natural environments.

  • Cultured Meat Production

    Advances, Challenges and Opportunities
    • 1 Edición
    • Zuhaib F. Bhat + 1 más
    • Inglés
    The ever-expanding human population calls for novel ways to produce protein of sufficient quality and quantity, however finite animal and land resources and increasing environmental concerns are already beginning to limit our capacity to produce an adequate protein supply. Novel technologies now allow for the production of cultured meat and seafood, offering a potentially lower carbon footprint and substantially eliminating animal suffering. Cultured Meat Production: Advances, Challenges, and Opportunities will discuss the existing technologies in this exciting field and the feasibility of the commercial production of fully structured cultured meat and seafood. In addition to covering the latest science, the book examines consumer perception, religious and cultural considerations, and regulatory aspects, such as quality assurance and food safety. The chapters are written by academic and industry experts from around the world at the forefront of this exciting field. Researchers, entrepreneurs, and advanced student audiences who are interested in getting up-to-speed on lab-grown meat won't want to miss this timely book.

  • Modern Food Preservation

    Intelligent and Sustainable Technologies for Safety and Shelf Life Extension
    • 1 Edición
    • Tanmay Sarkar
    • Inglés
    Modern Food Preservation: Intelligent and Sustainable Technologies for Safety and Shelf Life Extension addresses the evolving needs in food science research and industry for innovative, non-thermal, and sustainable preservation technologies. The book explores cutting-edge instrument-based methods that maintain food quality, safety, and nutritional integrity while aligning with global sustainability goals. It fills the critical gap between conventional preservation techniques and emerging smart technologies.It comprises detailed chapters authored by global experts covering topics such as cold plasma, pulsed electric fields, radio frequency pasteurization, nanozyme detection, and AI-integrated preservation systems. The comprehensive table of contents includes both fundamental principles and applied industrial perspectives, providing readers with technical guidance on the operation, scalability, and benefits of each technology. The inclusion of diverse tools reflects the latest advancements in precision, energy efficiency, and eco-friendly approaches in food preservation.Modern Food Preservation: Intelligent and Sustainable Technologies for Safety and Shelf Life Extension benefits food scientists, engineers, and industry professionals by equipping them with practical knowledge to implement next-generation preservation solutions. It empowers readers to future-proof their practices through sustainable, safe, and precise food preservation technologies essential for addressing food security and reducing waste.

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